Adamantinoma: A locally aggressive, osteolytic neoplasm of the long bones, probably of epithelial origin and most often involving the TIBIA.Fibrous Dysplasia of Bone: A disease of bone marked by thinning of the cortex by fibrous tissue containing bony spicules, producing pain, disability, and gradually increasing deformity. Only one bone may be involved (FIBROUS DYSPLASIA, MONOSTOTIC) or several (FIBROUS DYSPLASIA, POLYOSTOTIC).Ameloblastoma: An immature epithelial tumor of the JAW originating from the epithelial rests of Malassez or from other epithelial remnants of the ENAMEL from the developmental period. It is a slowly growing tumor, usually benign, but displays a marked propensity for invasive growth.Bone Diseases, DevelopmentalTibia: The second longest bone of the skeleton. It is located on the medial side of the lower leg, articulating with the FIBULA laterally, the TALUS distally, and the FEMUR proximally.Fibula: The bone of the lower leg lateral to and smaller than the tibia. In proportion to its length, it is the most slender of the long bones.Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Sarcoma, Ewing: A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females.Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.RNA-Binding Protein EWS: A ubiquitous hnRNP protein found in the CELL NUCLEUS and the CYTOPLASM. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS may play a role in neoplastic processes such as EWING SARCOMA.Proto-Oncogene Protein c-fli-1: A member of the c-ets family of transcription factors that is preferentially expressed in cells of hematopoietic lineages and vascular endothelial cells. It was originally identified as a protein that provides a retroviral integration site for integration of FRIEND MURINE LEUKEMIA VIRUS.Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.Sarcoma, Synovial: A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Spinal Curvatures: Deformities of the SPINE characterized by abnormal bending or flexure in the vertebral column. They may be bending forward (KYPHOSIS), backward (LORDOSIS), or sideway (SCOLIOSIS).Hammer Toe Syndrome: A condition characterized by a series of interrelated digital symptoms and joint changes of the lesser digits and METATARSOPHALANGEAL JOINTS of the FOOT. The syndrome can include some or all of the following conditions: hammer toe, claw toe, mallet toe, overlapping fifth toe, curly toe, EXOSTOSIS; HYPEROSTOSIS; interdigital heloma, or contracted toe.Knee Joint: A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA.Muscle Neoplasms: Tumors or cancer located in muscle tissue or specific muscles. They are differentiated from NEOPLASMS, MUSCLE TISSUE which are neoplasms composed of skeletal, cardiac, or smooth muscle tissue, such as MYOSARCOMA or LEIOMYOMA.Scoliosis: An appreciable lateral deviation in the normally straight vertical line of the spine. (Dorland, 27th ed)Athletic Injuries: Injuries incurred during participation in competitive or non-competitive sports.Foot Deformities: Alterations or deviations from normal shape or size which result in a disfigurement of the foot.Hamartoma: A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.Tissue Array Analysis: The simultaneous analysis of multiple samples of TISSUES or CELLS from BIOPSY or in vitro culture that have been arranged in an array format on slides or microchips.Femur: The longest and largest bone of the skeleton, it is situated between the hip and the knee.Radiology: A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease.Radiography: Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film).BooksAortic Valve Prolapse: The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to aortic regurgitation.Ion Exchange: Reversible chemical reaction between a solid, often one of the ION EXCHANGE RESINS, and a fluid whereby ions may be exchanged from one substance to another. This technique is used in water purification, in research, and in industry.Urodela: An order of the Amphibia class which includes salamanders and newts. They are characterized by usually having slim bodies and tails, four limbs of about equal size (except in Sirenidae), and a reduction in skull bones.Rats, Zucker: Two populations of Zucker rats have been cited in research--the "fatty" or obese and the lean. The "fatty" rat (Rattus norvegicus) appeared as a spontaneous mutant. The obese condition appears to be due to a single recessive gene.Growth Differentiation Factor 1: A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.Thionucleotides: Nucleotides in which the base moiety is substituted with one or more sulfur atoms.RNA Polymerase III: A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure where it transcribes DNA into RNA. It has specific requirements for cations and salt and has shown an intermediate sensitivity to alpha-amanitin in comparison to RNA polymerase I and II. EC 2.7.7.6.Craniopharyngioma: A benign pituitary-region neoplasm that originates from Rathke's pouch. The two major histologic and clinical subtypes are adamantinous (or classical) craniopharyngioma and papillary craniopharyngioma. The adamantinous form presents in children and adolescents as an expanding cystic lesion in the pituitary region. The cystic cavity is filled with a black viscous substance and histologically the tumor is composed of adamantinomatous epithelium and areas of calcification and necrosis. Papillary craniopharyngiomas occur in adults, and histologically feature a squamous epithelium with papillations. (From Joynt, Clinical Neurology, 1998, Ch14, p50)Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.Proto-Oncogene Proteins B-raf: A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.DNA Mutational Analysis: Biochemical identification of mutational changes in a nucleotide sequence.Pituitary Irradiation: Radiation therapy used to treat the PITUITARY GLAND.Stereotaxic Techniques: Techniques used mostly during brain surgery which use a system of three-dimensional coordinates to locate the site to be operated on.Dacarbazine: An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)Central Nervous System Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.Poly(ADP-ribose) Polymerases: Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.Antineoplastic Agents, Alkylating: A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.DNA Repair: The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.Leukocytes, Mononuclear: Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules.Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as flouride (FLUORIDES) to prevent dental caries.Positron-Emission Tomography: An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.Tomography, Emission-Computed: Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.Fluorodeoxyglucose F18: The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.Radiopharmaceuticals: Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)Fluorine Radioisotopes: Unstable isotopes of fluorine that decay or disintegrate emitting radiation. F atoms with atomic weights 17, 18, and 20-22 are radioactive fluorine isotopes.

Allograft reconstruction for bone sarcoma of the tibia in the growing child. (1/12)

The outcome of tibial allograft reconstruction after resection of a tumour is inconsistent and has a high rate of failure. There are few reports on the use of tibial allografts in children with open growth plates. We performed 21 allograft reconstructions (16 osteoarticular, five intercalary) in 19 consecutive patients between seven and 17 years of age. Two had Ewing's sarcoma, one an adamantinoma and 16 osteosarcoma, one with multifocal disease. Five patients have died; the other 14 were free from disease at the time of follow-up. Six surviving patients (eight allograft reconstructions) continue to have good or excellent function at a mean of 59 months (14 to 132). One patient has poor function at 31 months. The other seven patients have a good or excellent function after additional procedures including exchange of the allograft and resurfacing or revision to an endoprosthesis at a mean of 101 months (43 to 198). The additional operations were performed at a mean of 47 months (20 to 84) after the first reconstruction. With the use of allograft reconstruction in growing children, joints and growth plates may be preserved, at least partially. Although our results remain inconsistent, tibial allograft reconstruction in selected patients may restore complete and durable function of the limb.  (+info)

A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the literature. (2/12)

Adamantinoma is known as a low-grade malignant biphasic tumor. Classic adamantinoma is in general characterized by admixture of both epithelial and osteofibrous components that are associated with various proportions and differentiation patterns. Osteofibrous dysplasia (OFD) is a self-limited benign fibro-osseous lesion of bone during infancy and childhood. OFD-like adamantinoma is characterized by predominance of osteofibrous tissues, in which small groups of epithelial cells are only detected by careful search or immunohistochemistry. There have been controversies as to the potential correlation among OFD, OFD-like adamantinoma and classic adamantinoma. We report an unusual case of adamantinoma arising in the tibia, with an extensive review of the literature. The present findings suggest a direct correlation between OFD-like adamantinoma and classic adamantinoma. At the age of 12 years, the tibial biopsy lesion was diagnosed as OFD. At the age of 23, the lesion became larger and more destructive on x-ray films. The biopsy lesion was diagnosed as classic adamantinoma. Wide excision was performed. The primary lesion was retrospectively diagnosed as OFD-like adamantinoma because of presence of keratin-positive epithelial cells within the stroma. At five years after surgery, the patient was free from recurrence or metastasis. The retrospective histological findings of OFD-like adamantinoma in the original biopsy and of a classic adamantinoma in all sections of the later resection specimen raised the possibility of an unusual progression of OFD-like adamantinoma to a classic adamantinoma. The present case and the literature review suggest that an OFD-like adamantinoma may be a precursor lesion of classic adamantinoma. Therefore, the possibility of progression of OFD-like adamantinoma to a classic adamantinoma should be kept in mind, particularly when the destructive changes are seen radiologically.  (+info)

Osteofibrous dysplasia of the tibia. Is there a need for a radical surgical approach? (3/12)

Osteofibrous dysplasia is an unusual developmental condition of childhood, which almost exclusively affects the tibia. It is thought to follow a slowly progressive course and to stabilise after skeletal maturity. The possible link with adamantinoma is controversial and some authors believe that they are part of one histological process. We retrospectively reviewed 16 patients who were diagnosed as having osteofibrous dysplasia initially or on the final histological examination. Their management was diverse, depending on the severity of symptoms and the extent of the lesion. Definitive (extraperiosteal) surgery was localised "shark-bite" excision for small lesions in five patients. Extensive lesions were treated by segmental excision and fibular autograft in six patients, external fixation and bone transport in four and proximal tibial replacement in one. One patient who had a fibular autograft required further excision and bone transport for recurrence. Six initially underwent curettage and all had recurrence. There were no recurrences after localised extraperiosteal excision or bone transport. There were three confirmed cases of adamantinoma. The relevant literature is reviewed. We recommend extraperiosteal excision in all cases of osteofibrous dysplasia, with segmental excision and reconstruction in more extensive lesions.  (+info)

Fibular osteoadiposal flap for treatment of tibial adamantinoma: a case report. (4/12)

We treated a case with left tibial adamantinoma by use of a contralateral fibular osteoadiposal flap. The donor site of conventional fibular osteocutaneous flap must be covered with a skin graft because if we close the donor skin defect directly, compartment syndrome might occur. We were able to close the donor skin defect because this combined type flap included only a small monitoring skin paddle. We present herein the utility of the osteoadiposal flap and show the value of a skin-sparing approach with a minimal aesthetic defect.  (+info)

Preliminary report of expression of bax in oral cavity pathologies. (5/12)

Bax is considered one of major effectors of apoptosis--programmed cell death. Immunohistochemical analysis of in vitro patterns of bax expression was mostly investigated in mammalian cell lines and tissues. The present study is the first in vivo molecular analysis of bax expression in oral cavity pathologies. The study population consisted of 45 patients with hyperplasia, neoplasm in situ malignancy, and carcinoma. Biopsies were taken from incision line, tumour section, and healthy tissue. bax expression was investigated depending on the site of biopsy material sampling and final histopathology result. No statistically significant difference was demonstrated in bax expression between four hyperplasia subgroups. However, statistically significant differences in bax expression were found between the three basic study groups (P = 0.001). Statistically significant differences in bax expression were demonstrated depending on tissue collection site (P = 0.0002). We conclude that differences in bax expression may play a role in the pathogenesis of neoplastic disease.  (+info)

Adamantinoma of the tibia with late skeletal metastasis: an unusual presentation. (6/12)

Adamantinoma is a rare tumour of long bones that occurs most commonly in the tibia. Its pathogenesis is unknown. It is locally aggressive and recurrences are common after resection. Metastases have been reported in 10% to 20% of cases, most commonly in the lungs and rarely in the lymph nodes. We report a patient who developed a skeletal metastasis four years after resection of the primary tumour. There was no evidence of recurrence at the primary site or of secondary deposits in the lungs.  (+info)

Treatment of osteofibrous dysplasia and associated lesions. (7/12)

PURPOSE: To report long term treatment outcomes of osteofibrous dysplasia and association with adamantinoma. PATIENTS AND METHODS: From January 1984 to July 2001, 14 patients with osteofibrous dysplasia were followed for an average of 108 months (78 to 260 months). Our patient group consisted of 6 men and 8 women, with a mean age of 13.9 years (2 to 65 years). We reviewed the clinical and pathological features of all 14 patients. RESULTS: Thirteen patients had a lesion in the tibia, while one patient had lesions in both the tibia and the fibula. Initial treatments were observation after biopsy (6 patients), curettage with or without a bone graft (3 patients), resection followed by a free vascularized fibular bone graft (4 patients), or resection and regeneration with the Ilizarov external fixation (1 patient). Curettage was performed on 6 patients due to recurrence or progression after the initial treatment. Among these patients, one was diagnosed with AD from the biopsy of the recurrent lesion. This patient was further treated by segmental resection and pasteurization. After the initial pathology slides of the 13 patients were reviewed with immunohistochemical cytokeratin staining, one patient diagnosis was changed from osteofibrous dysplasia to osteofibrous dysplasia-like adamantinoma. CONCLUSION: Some patients with osteofibrous dysplasia require close observation because of the high association risk between osteofibrous dysplasia and adamantinoma, Immunohistochemical staining may be helpful in differentiating these two diagnoses.  (+info)

Analysis of stromal cells in osteofibrous dysplasia and adamantinoma of long bones. (8/12)

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MalaCards based summary : Adamantinoma of Long Bones, also known as long bone adamantinoma, is related to tibial adamantinoma and biphasic synovial sarcoma. An important gene associated with Adamantinoma of Long Bones is EGF (Epidermal Growth Factor), and among its related pathways/superpathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Lung fibrosis. Affiliated tissues include long bones, bone and eye, and related phenotypes are neoplasm and pathologic fracture ...
TY - JOUR. T1 - Adamantinoma of the distal femur diagnosed 5 years after initial surgery. T2 - A case report. AU - Cao, Kai. AU - Susa, Michiro. AU - Watanabe, Itsuo. AU - Nishimoto, Kazumasa. AU - Horiuchi, Keisuke. AU - Sasaki, Aya. AU - Hayashi, Yuichiro. AU - Emoto, Katsura. AU - Kameyama, Kaori. AU - Nakamura, Masaya. AU - Matsumoto, Morio. AU - Morioka, Hideo. PY - 2016/6/23. Y1 - 2016/6/23. N2 - Background: Adamantinoma arising in the femur is extremely rare. We report a case of an adamantinoma occurring in the right medial femoral condyle that was diagnosed 5 years after the primary surgery. Case presentation: A 74-year-old Asian woman first complained of right knee pain without any cause. Radiographs demonstrated a 4×4.5 cm osteolytic lesion in her medial femoral condyle. Magnetic resonance imaging revealed a lesion which showed low signal on both T1 and T2-weighted image, and enhanced signal with gadolinium contrast administration. She underwent a wide resection of the lesion and was ...
TY - JOUR. T1 - Frequent immunoexpression of TGF-β1, FGF-2 and BMP-2 in fibroblast-like cells in osteofibrous dysplasia. AU - Sakamoto, Akio. AU - Oda, Yoshinao. AU - Iwamoto, Yukihide. AU - Tsuneyoshi, Masazumi. PY - 2007/3. Y1 - 2007/3. N2 - Osteofibrous dysplasia (OFD) and fibrous dysplasia (FD) are both benign bone lesions which comprise the proliferation of fibroblast-like cells with bone formation, and these fibroblast-like cells have the phenotype of osteoprogenitor cells. The roentgenograph of OFD shows a heterogeneous osteolytic lesion with surrounding osteosclerosis, whereas FD is typically characterized by a rather homogeneous osteolytic lesion, or ground-glass appearance, with a smaller amount of surrounding osteosclerosis. Growth factors of transforming growth factor-β1 (TGF-β1), fibroblast growth factor-2 (FGF-2) and bone morphogenetic protein-2 (BMP-2) modulate bone differentiation. Expression of these growth factors was examined in the fibroblast-like cells of 16 cases of ...
Adamantinoma usually presents as an intraosseous, intracortical stage I-A sarcoma.. This low-grade, slowly-growing malignancy metastasizes in about 20 percent of cases by both hematogenous and lymphatic routes to other parts of the body, usually to the lungs or nearby lymph nodes. Of these cases, about 15 percent of the patients die.. Young females seem to be at the highest risk for early demise with the average age of death being 33 years compared to 48 years for men.. ...
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Memorial Sloan Kettering surgeon Nicola Fabbri has 20 years of experience in treating musculoskeletal cancers, including osteosarcoma, Ewing Sarcoma, chondrosarcoma, soft tissue sarcomas, giant-cell tumor, chordoma, adamantinoma, osteofibrous dysplasia, angiosarcoma, and other vascular tumors.
Poster: ECR 2015 / B-0912 / Can ultrasound replace MRI in assessment of nerve entrapment in osteofibrous tunnels in the upper extremity by: A. Abdel Maguid, Y. M. Tohamey, T. Taymour, L. Adel; Cairo/EG
Ameloblastoma (from the early English word amel, meaning enamel + the Greek word blastos, meaning germ) is a rare, benign or cancerous tumor of odontogenic epithelium (ameloblasts, or outside portion, of the teeth during development) much more commonly appearing in the lower jaw than the upper jaw. It was recognized in 1827 by Cusack. This type of odontogenic neoplasm was designated as an adamantinoma in 1885 by the French physician Louis-Charles Malassez. It was finally renamed to the modern name ameloblastoma in 1930 by Ivey and Churchill. While these tumors are rarely malignant or metastatic (that is, they rarely spread to other parts of the body), and progress slowly, the resulting lesions can cause severe abnormalities of the face and jaw. Additionally, because abnormal cell growth easily infiltrates and destroys surrounding bony tissues, wide surgical excision is required to treat this disorder. If an aggressive tumor is left untreated, it can obstruct the nasal and oral airways making it ...
Looking for odontogenic epithelioma? Find out information about odontogenic epithelioma. An epithelial tumor associated with the enamel organ; cells of basal layers resemble the ameloblast. Also known as adamantinoma Explanation of odontogenic epithelioma
Abdominal Aortic Aneurysm Imaging Abdominal Aortic Aneurysm Rupture Imaging Acalculous Cholecystitis Imaging Acetabulum Fracture Imaging Achalasia Imaging Achondroplasia Imaging Acquired Temporal-Bone Cholesteatoma Imaging Acute Cholecystitis Imaging Acute Epiglottitis Imaging Acute Myocardial Infarct Imaging Acute Obstructive Uropathy Imaging Acute Pancreatitis Imaging Acute Pulmonary Embolism (Helical CT) Acute Pyogenic Osteomyelitis Imaging Adamantinoma Imaging Adenomyomatosis Imaging Adenomyosis Imaging…
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This type of odontogenic neoplasm was designated as an adamantinoma in 1885 by the French physician Louis-Charles Malassez. It ...
"A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the ... Several authors have related this non-neoplastic lesion to adamantinoma - a tumor involving subcutaneous long bones - stating ...
... adamantinoma MeSH C05.116.231.343 --- femoral neoplasms MeSH C05.116.231.754 --- skull neoplasms MeSH C05.116.231.754.450 --- ...
... adamantinoma MeSH C04.588.149.276 --- femoral neoplasms MeSH C04.588.149.721 --- skull neoplasms MeSH C04.588.149.721.450 --- ...
... a bulky hydrocarbon Adamantinoma, a form of bone cancer. ...
Adamantinoma - Adhesive capsulitis of shoulder - Advanced trauma life support - Ainhum - Akin osteotomy - Albers-Schonberg ...
NOS Adamantinoma, NOS (except of long bones M9261/3) M9310/3 Ameloblastoma, malignant Adamantinoma, NOS (except of long bones ... malignant M9260/3 Ewing's sarcoma/tumor M9261/3 Adamantinoma of long bones M9262/0 Ossifying fibroma Fibro-osteoma Osteofibroma ...
Benign osteofibrous dysplasia may be a precursor of adamantinoma or a regressive phase of adamantinoma. Histologically, islands ... "A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the ... Adamantinoma (from the Greek word adamantinos, meaning "very hard") is a rare bone cancer, making up less than 1% of all bone ... "Adamantinoma: Overview - eMedicine". Archived from the original on 25 December 2008. Retrieved 2009-01-04. Fischer B. Uber ein ...
Adamantinoma. *Adams-Nance syndrome. *Adams-Oliver syndrome. *Adams-Stokes syndrome. *Addison's disease ...
Pain may be relieved by nonsteroidal anti-inflammatory drugs.. Treatment varies based on the health of the patient. If he/she is otherwise healthy and is not significantly bothered by the pain, the tumor is treated symptomatically with anti-inflammatories. If this therapy fails or the location of the tumor could lead to growth disturbances, scoliosis, or osteoarthritis, surgical or percutaneous ablation may be considered.[10] If surgery is preferred, the individual may be referred to a podiatrist or an orthopedic surgeon to perform the procedure. Post-surgery therapy and strengthening may be needed, depending on the tumor location and health of the individual. While shown to be effective, surgical resection has many potential complications, including difficult intraoperative identification of the tumor, local recurrence from incomplete resection, and resection of weight bearing bone that can necessitate prolonged hospital stays and complicate recovery.[11]. Recently, CT guided radiofrequency ...
MalaCards based summary : Adamantinoma of Long Bones, also known as long bone adamantinoma, is related to tibial adamantinoma ... MalaCards integrated aliases for Adamantinoma of Long Bones:. Name: Adamantinoma of Long Bones 56 58 43 ... MalaCards organs/tissues related to Adamantinoma of Long Bones:. 40 Bone, Eye, Testes, Colon, Breast, Skin ... Morphologic diversity of long bone adamantinoma. The concept of differentiated (regressing) adamantinoma and its relationship ...
Background: Adamantinoma arising in the femur is extremely rare. We report a case of an adamantinoma occurring in the right ... N2 - Background: Adamantinoma arising in the femur is extremely rare. We report a case of an adamantinoma occurring in the ... AB - Background: Adamantinoma arising in the femur is extremely rare. We report a case of an adamantinoma occurring in the ... abstract = "Background: Adamantinoma arising in the femur is extremely rare. We report a case of an adamantinoma occurring in ...
Adamantinoma. Neuroectodermal Tumors. Neoplasms, Germ Cell and Embryonal. Neoplasms by Histologic Type. Neoplasms. Neoplasms, ...
Kitsoulis P, Charchanti A, Paraskevas G, Marini A, Karatzias G: Adamantinoma. Acta Orthop Belg; 2007 Aug;73(4):425-31. [ ... Fujii H, Honoki K, Enomoto Y, Kasai T, Kido A, Amano I, Kumamoto M, Morishita T, Mii Y, Nonomura A, Takakura Y: Adamantinoma- ... Adamantinoma is one of the rarest low-grade malignant bone tumours, representing less than 1% of them. ... Title] Adamantinoma-like Ewings sarcoma with EWS-FLI1 fusion gene: a case report. ...
The differential diagnosis includes also nonossifying fibroma, osteofibrous dysplasia, aneurysmal bone cyst, adamantinoma, ...
... Albert N. Van Geel,1,2 Hans M. Hazelbag,3 Rob Slingerland,4 and Margit I. Vermeulen1 ... All types of adamantinoma should be treated by complete en bloc resection. For patients with metastatic spread to the lungs, ... This report describes a patient with a primary long bone adamantinoma. The lesion was initially wrongly diagnosed as fibrous ... the tumour had progressed from an osteofibrous dysplasia-like to a full-blown classic adamantinoma, with metastatic potential ...
Benign osteofibrous dysplasia may be a precursor of adamantinoma or a regressive phase of adamantinoma. Histologically, islands ... "A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the ... Adamantinoma (from the Greek word adamantinos, meaning "very hard") is a rare bone cancer, making up less than 1% of all bone ... "Adamantinoma: Overview - eMedicine". Archived from the original on 25 December 2008. Retrieved 2009-01-04. Fischer B. Uber ein ...
... adamantinoma explanation free. What is adamantinoma? Meaning of adamantinoma medical term. What does adamantinoma mean? ... Looking for online definition of adamantinoma in the Medical Dictionary? ... adamantinoma. /ad·a·man·ti·no·ma/ (ad″ah-man″tĭ-no´mah) ameloblastoma.. adamantinoma, adamantoblastoma. See ameloblastoma. ... Our understanding of the relationship among classic adamantinoma, differentiated adamantinoma (osteofibrous dysplasia-like ...
Adamantinoma of Long Bone (extragnathic adamantinoma): Adamantinoma is a rare primary low-grade malignant tumor of bone that is ... Adamantinoma of Long Bone (extragnathic adamantinoma): Adamantinoma is a rare primary low-grade malignant tumor of bone that is ... Adamantinoma at Orthonet Location: http://www.orthonet.on.ca/adamantinoma/ Adamantinoma - 1o bone tumor with predilection for ... Adamantinoma of the long bone is not related to adamantinoma or ameloblastoma of the mandible and maxilla, which is derived ...
... adamantoma explanation free. What is adamantoma? Meaning of adamantoma medical term. What does adamantoma mean? ... Looking for online definition of adamantoma in the Medical Dictionary? ... adamantoma. adamantoma. /ad·a·man·to·ma/ (ad″ah-man-to´mah) ameloblastoma.. adamantoblastoma, adamantoma. see ameloblastoma. ... Adamantoma , definition of adamantoma by Medical dictionary https://medical-dictionary.thefreedictionary.com/adamantoma ...
What is plexiform adamantinoma? Meaning of plexiform adamantinoma medical term. What does plexiform adamantinoma mean? ... Looking for online definition of plexiform adamantinoma in the Medical Dictionary? plexiform adamantinoma explanation free. ... redirected from plexiform adamantinoma) fibroma. [fi-bro´mah] (pl. fibromas, fibro´�mata) a tumor composed mainly of fibrous or ... Plexiform adamantinoma , definition of plexiform adamantinoma by Medical dictionary https://medical-dictionary. ...
Adamantinoma is low grade malignant tumor of fibroblast origin. Also called as primary epidermoid carcinoma of bone, malignan ... Rarely,(11;22) translocations have been reported in case of adamantinoma, and is termed adamantinoma-like ewings sarcoma.11 11 ... Pain may be present due to history of repetitive trauma associated with adamantinoma.7 Adamantinoma is low grade malignant ... Adamantinoma is low grade malignant tumor of fibroblast origin. Also called as primary epidermoid carcinoma of bone, malignant ...
Adamantinoma is a rare tumour of long bones, representing less than 1% of them. Adamantinoma commonly occurs in the tibia. It ... Adamantinoma of the tibia and fibula with pulmonary metastasis: an unusual presentation ... Adamantinoma of the tibia and fibula with pulmonary metastasis: an unusual presentation ...
Adamantinoma-like Ewing sarcoma (ALES) is a rare variant of Ewing sarcoma that is defined by complex epithelial differentiation ... Adamantinoma-like Ewings sarcoma and Ewings-like adamantinoma. The t(11; 22), t(21; 22) status. J Pathol. 2001;195(2):218-21. ... Adamantinoma-Like Ewings family tumor of the sino nasal region: a case report and a brief review of literature. Case Rep ... Adamantinoma-like Ewing family tumor of soft tissue associated with the vagus nerve: a case report and review of the literature ...
Todays topic is - ADAMANTINOMA ! (and no its not what would only happen to Wolverine! Haha see what I did there ?! ) ...
Adamantinoma Adamantinoma is a rare malignant bone tumor most commonly found in the tibia. Contact the Orthopaedic Oncology ...
Adamantinoma and hamartoma tissue array, 40 cases_80 cores \ MC804 for more molecular products just contact us ... Adamantinoma and hamartoma tissue microarray, containing 22 cases of bone adamantinoma, 18 hamartoma of kidney and liver, ... We have also other products like : Adamantinoma and hamartoma tissue array, 40 cases_80 cores. Related products : Adamantinoma ... Index / US Biomax / Adamantinoma and hamartoma tissue array, 40 cases_80 cores / Product Detail : MC804 Adamantinoma and ...
The name adamantinoma was given to this tumor because of its histologic resemblance to the more common adamantinoma ( ... Figure 24.2. Adamantinoma involving the tibia and fibula in a 19-year-old woman. A: Extensive involvement of the cortex of the ... Some cases of adamantinoma have also been reported in short tubular bones, but the diagnoses in these cases have to be ... Adamantinoma of long bones is a peculiar neoplasm that, on the basis of radiographic and pathologic features, arises within the ...
Tumor Library - Cancer Oncology - Welcome to the James O. Johnston Orthopaedic Oncology Tumor Library. This site is intended to offer the oppotunity to cancer research of Orthopaedic Oncology diagnosis slides and imagery from Dr. Johnson s personal library.
Adamantinoma-like Ewings sarcoma. Genomic confirmation, phenotypic drift. Julia A. Bridge, Mary E. Fidler, James R. Neff, ... Adamantinoma-like Ewings sarcoma: Genomic confirmation, phenotypic drift. American Journal of Surgical Pathology. 1999 Feb 1; ... Adamantinoma-like Ewings sarcoma : Genomic confirmation, phenotypic drift. / Bridge, Julia A.; Fidler, Mary E.; Neff, James R ... keywords = "Adamantinoma, EWS/FLI1, Ewings sarcoma, Karyotype, RT/PCR",. author = "Bridge, {Julia A.} and Fidler, {Mary E.} ...
1 adamantinoma of jaw 2005:2010[pubdate] *count=100 25 results Searchbox Export PDF RSS Email Delete Email this search result ... Kitsoulis P, Charchanti A, Paraskevas G, Marini A, Karatzias G: Adamantinoma. Acta Orthop Belg; 2007 Aug;73(4):425-31. [ ... Ameloblastoma (adamantinoma) is a benign neoplasm deriving from the enamel organ.. * About 20% of described cases of ... Adamantinoma is one of the rarest low-grade malignant bone tumours, representing less than 1% of them. ...
So-called "Adamantinoma of Long Bone". Zand, Abbas; Chambers, George H.; Street, Dana M. ...
Adamantinoma of Long Bone (extragnathic adamantinoma): Adamantinoma is a rare primary low-grade malignant tumor of bone that is ... Adamantinoma of the long bone is not related to adamantinoma or ameloblastoma of the mandible and maxilla, which is derived ... state that there is an entity known as osteofibrous dyplasia-like adamantinoma (differentiated adamantinoma) that may be a ... Adamantinoma usually presents as an intraosseous, intracortical stage I-A sarcoma.. This low-grade, slowly-growing malignancy ...
Preoperative radiographs show a teenage patient with a tibial adamantinoma (A-B). The decision was made to treat the patient ...
24.89 Adamantinoma of tibia. Lack of cohesiveness of tumor cells in some of the islands results in a pseudovascular appearance ... 24.91 Immunoreactivity for keratin in the tumor cells of adamantinoma of tibia. ...
  • The histological similarity of the lung tumor and the femoral tumor led to the diagnosis of adamantinoma arising in her right medial femoral condyle with metastasis to the upper lobe of her right lung. (elsevier.com)
  • We report a case of an adamantinoma occurring in the right medial femoral condyle that was diagnosed 5 years after the primary surgery. (elsevier.com)
  • Adamantinoma-like Ewing family tumors of the head and neck: a pitfall in the differential diagnosis of basaloid and myoepithelial carcinomas. (springer.com)
  • Ongkeko M, Zeck J, deBrito P. Molecular testing uncovers an adamantinoma-like ewing family of tumors in the thyroid: case report and review of literature. (springer.com)
  • 6 In this case study, we have presented a rare histological acanthomatous variant of adamantinoma of the right tibia with metastases to the right inguinal region. (ukessays.com)
  • 2 The exact origin of adamantinoma is unknown, the classic variant is composed of epithelial cells and osteofibrous components. (ukessays.com)
  • I joined CanTeen as a patient member after being diagnosed with a rare form of bone cancer called Adamantinoma. (scoop.co.nz)
  • Adamantinoma was considered, however, the diagnosis was inconclusive due to the unusual localization and her age. (elsevier.com)
  • Conclusion: In this case report, we report the clinical, radiographic, and histological features of an adamantinoma arising in the distal femur with a review of the literature. (elsevier.com)
  • This type of odontogenic neoplasm was designated as an adamantinoma in 1885 by the French physician Louis-Charles Malassez. (wikipedia.org)
  • Contact the Orthopaedic Oncology Service at Mass General for more information about treatment for Adamantinoma. (massgeneral.org)
  • Some cases of adamantinoma have also been reported in short tubular bones, but the diagnoses in these cases have to be considered suspect. (musculoskeletalkey.com)
  • The first theory, the embryogenetic theory, suggests that the adamantinomatous type (so-called adamantinoma) arises from epithelial remnants of the Rathke pouch or the craniopharyngeal duct (the embryonal structure along which the eventual adenohypophysis and infundibulum migrate). (medscape.com)