Acyclovir. Medical search

A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.

A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)

Infection of the genitals (GENITALIA) with HERPES SIMPLEX VIRUS in either the males or the females.

An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed)

Herpes simplex, caused by type 1 virus, primarily spread by oral secretions and usually occurring as a concomitant of fever. It may also develop in the absence of fever or prior illness. It commonly involves the facial region, especially the lips and the nares. (Dorland, 27th ed.)

A species of SIMPLEXVIRUS associated with genital infections (HERPES GENITALIS). It is transmitted by sexual intercourse and close personal contact.

A genus of the family HERPESVIRIDAE, subfamily ALPHAHERPESVIRINAE, consisting of herpes simplex-like viruses. The type species is HERPESVIRUS 1, HUMAN.

A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.

An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.

An ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)

Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.

Virus infection of the Gasserian ganglion and its nerve branches characterized by pain and vesicular eruptions with much swelling. Ocular involvement is usually heralded by a vesicle on the tip of the nose. This area is innervated by the nasociliary nerve.

A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.

Stomatitis caused by Herpesvirus hominis. It usually occurs as acute herpetic stomatitis (or gingivostomatitis), an oral manifestation of primary herpes simplex seen primarily in children and adolescents.

The type species of VARICELLOVIRUS causing CHICKENPOX (varicella) and HERPES ZOSTER (shingles) in humans.

A form of herpetic keratitis characterized by the formation of small vesicles which break down and coalesce to form recurring dendritic ulcers, characteristically irregular, linear, branching, and ending in knoblike extremities. (Dictionary of Visual Science, 3d ed)

An enzyme that catalyzes the conversion of ATP and thymidine to ADP and thymidine 5'-phosphate. Deoxyuridine can also act as an acceptor and dGTP as a donor. (From Enzyme Nomenclature, 1992) EC 2.7.1.21.

The type species of SIMPLEXVIRUS causing most forms of non-genital herpes simplex in humans. Primary infection occurs mainly in infants and young children and then the virus becomes latent in the dorsal root ganglion. It then is periodically reactivated throughout life causing mostly benign conditions.

The giving of drugs, chemicals, or other substances by mouth.

The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.

A highly contagious infectious disease caused by the varicella-zoster virus (HERPESVIRUS 3, HUMAN). It usually affects children, is spread by direct contact or respiratory route via droplet nuclei, and is characterized by the appearance on the skin and mucous membranes of successive crops of typical pruritic vesicular lesions that are easily broken and become scabbed. Chickenpox is relatively benign in children, but may be complicated by pneumonia and encephalitis in adults. (From Dorland, 27th ed)

The expelling of virus particles from the body. Important routes include the respiratory tract, genital tract, and intestinal tract. Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).

Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.

Inflammation of brain tissue caused by infection with the varicella-zoster virus (HERPESVIRUS 3, HUMAN). This condition is associated with immunocompromised states, including the ACQUIRED IMMUNODEFICIENCY SYNDROME. Pathologically, the virus tends to induce a vasculopathy and infect oligodendrocytes and ependymal cells, leading to CEREBRAL INFARCTION, multifocal regions of demyelination, and periventricular necrosis. Manifestations of varicella encephalitis usually occur 5-7 days after onset of HERPES ZOSTER and include HEADACHE; VOMITING; lethargy; focal neurologic deficits; FEVER; and COMA. (From Joynt, Clinical Neurology, 1996, Ch 26, pp29-32; Hum Pathol 1996 Sep;27(9):927-38)

A syndrome characterized by the acute onset of unilateral FACIAL PARALYSIS which progresses over a 2-5 day period. Weakness of the orbicularis oculi muscle and resulting incomplete eye closure may be associated with corneal injury. Pain behind the ear often precedes the onset of paralysis. This condition may be associated with HERPESVIRUS 1, HUMAN infection of the facial nerve. (Adams et al., Principles of Neurology, 6th ed, p1376)

A pyrimidine nucleoside formed in the body by the deamination of CYTARABINE.

Skin diseases caused by viruses.

A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.

An analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.

The mechanism by which latent viruses, such as genetically transmitted tumor viruses (PROVIRUSES) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. It may be effected by various endogenous and exogenous stimuli, including B-cell LIPOPOLYSACCHARIDES, glucocorticoid hormones, halogenated pyrimidines, IONIZING RADIATION, ultraviolet light, and superinfecting viruses.

A carrier or inert medium used as a solvent (or diluent) in which the medicinally active agent is formulated and or administered. (Dictionary of Pharmacy, 1986)

An alkylamino-alcohol complex of inosine used in the treatment of a variety of viral infections. Unlike other antiviral agents, it acts by modifying or stimulating cell-mediated immune processes rather than acting on the virus directly.

A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.

The return of a sign, symptom, or disease after a remission.

A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus.

A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed)

Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.

Mechanical food dispensing machines.

The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.

The profession of writing. Also the identity of the writer as the creator of a literary production.

A publication issued at stated, more or less regular, intervals.

The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.

A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.

The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)

A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.

Prudent standard preventive measures to be taken by professional and other health personnel in contact with persons afflicted with a communicable disease, to avoid contracting the disease by contagion or infection. Precautions are especially applicable in the diagnosis and care of AIDS patients.

Introduction of substances into the body using a needle and syringe.

The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or the mongoloid facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed)

Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. (1/1121)

The effect of an extensive prophylactic antimicrobial regimen was prospectively assessed in 126 patients after high-dose chemotherapy and autologous PBSC. They received ciprofloxacin (500 mg/12 h), acyclovir (200 mg/6 h), and itraconazole (200 mg/12 h) orally until neutrophil recovery. Febrile patients received i.v. imipenem (500 mg/6 h) to which vancomycin and amikacin were added if fever persisted for 2-3 and 5 days, respectively. Amphotericin B lipid complex was further given on day 7 or 8 of fever. Median times for a neutrophil count of >0.5 x 10(9)/l and a platelet count of >20 x 10(9)/l were 9 and 11 days. Severe neutropenia (<0.1 x 10(9)/l) lasted for a median of 5 days in which 72% of febrile episodes and 50% of cases of bacteremia occurred. Gram-positive bacteria were isolated in 30 of 40 episodes of bacteremia, 25 of which were caused by Staphylococcus epidermidis. Clinical foci were the intravascular catheter in 35 cases, respiratory infection in 11, cellulitis in two, anal abscess in one, and neutropenic enterocolitis in one. The high incidence of febrile episodes (94%) and bacteremias (31%) may be due to the lack of efficacy of antimicrobial prophylaxis and the persistence of a 5-day period of severe neutropenia. (+info)

B cell lymphoproliferative disorders following hematopoietic stem cell transplantation: risk factors, treatment and outcome. (2/1121)

Twenty-six cases of B cell lymphoproliferative disorder (BLPD) were identified among 2395 patients following hematopoietic stem cell transplants (HSCT) for which an overall incidence of BLPD was 1.2%. The true incidence was probably higher, since 9/26 of the diagnoses were made at autopsy. No BLPD was observed following autologous HSCT, so risk factor analyses were confined to the 1542 allogeneic HSCT. Factors assessed were HLA-mismatching (> or = 1 antigen), T cell depletion (TCD), presence of acute GvHD (grades II-IV), donor type (related vs unrelated), age of recipient and donor, and underlying disease. Factors found to be statistically significant included patients transplanted for immune deficiency and CML, donor age > or = 18 years, TCD, and HLA-mismatching, with recipients of combined TCD and HLA-mismatched grafts having the highest incidence. Factors found to be statistically significant in a multiple regression analysis were TCD, donor age and immune deficiency, although 7/8 of the patients with immunodeficiencies and BLPD received a TCD graft from a haploidentical parent. The overall mortality was 92% (24/26). One patient had a spontaneous remission, but subsequently died >1 year later of chronic GVHD. Thirteen patients received therapy for BLPD. Three patients received lymphocyte infusions without response. The only patients with responses and longterm survival received alpha interferon (alphaIFN). Of seven patients treated with alphaIFN there were four responses (one partial and three complete). These data demonstrate that alphaIFN can be an effective agent against BLPD following HSCT, if a timely diagnosis is made. (+info)

Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line. (3/1121)

The results of previous work performed in our laboratory using an in situ perfusion technique in rats and rabbit apical brush border membrane vesicles have suggested that the intestinal uptake of valacyclovir (VACV) appears to be mediated by multiple membrane transporters. Using these techniques, it is difficult to characterize the transport kinetics of VACV with each individual transporter in the presence of multiple known or unknown transporters. The purpose of this study was to characterize the interaction of VACV and the human intestinal peptide transporter using Chinese hamster ovary (CHO) cells that overexpress the human intestinal peptide transporter (hPEPT1) gene. VACV uptake was significantly greater in CHO cells transfected with hPEPT1 than in cells transfected with only the vector, pcDNA3. The optimum pH for VACV uptake was determined to occur at pH 7.5. Proton cotransport was not observed in hPEPT1/CHO cells, consistent with previously observed results in tissues and Caco-2 cells. VACV uptake was concentration dependent and saturable with a Michaelis-Menten constant and maximum velocity of 1.64 +/- 0.06 mM and 23.34 +/- 0.36 nmol/mg protein/5 min, respectively. A very similar Km value was obtained in hPEPT1/CHO cells and in rat and rabbit tissues and Caco-2 cells, suggesting that hPEPT1 dominates the intestinal transport properties of VACV in vitro. VACV uptake was markedly inhibited by various dipeptides and beta-lactam antibiotics, and Ki values of 12.8 +/- 2.7 and 9.1 +/- 1.2 mM were obtained for Gly-Sar and cefadroxil at pH 7.5, respectively. The present results demonstrate that VACV is a substrate for the human intestinal peptide transporter in hPEPT1/CHO cells and that although transport is pH dependent, proton cotransport is not apparent. Also, the results demonstrate that the hPEPT1/CHO cell system has use in investigating the transport kinetics of drugs with the human intestinal peptide transporter hPEPT1; however, the extrapolation of these transport properties to the in vivo situation requires further investigation. (+info)

Management of human cytomegalovirus infection and disease after allogeneic bone marrow transplantation. (4/1121)

BACKGROUND AND OBJECTIVE: Human cytomegalovirus (HCMV) infection and disease remain a major cause of morbidity and mortality after bone marrow transplantation. HCMV disease, especially pneumonitis, may be treated with ganciclovir and immunoglobulin but even so the outcome is poor with mortality rates of 30-70%. It is therefore imperative to treat HCMV infection before it develops into disease. The aim of this article is to describe the main strategies used to prevent HCMV infection and to improve the survival after CMV disease in bone marrow transplant recipients. INFORMATION SOURCES: In the present review, we examined personal papers in this field and articles published in journals covered by the Science Citation Index and Medline. STATE OF THE ART: Major advances have been made in preventing HCMV infection and disease through two different approaches, both of which reduce HCMV induced morbidity and mortality: In pre-emptive therapy, patients are given ganciclovir when HCMV infection is first identified and this is continued 3-4 months after transplantation; in prophylactic therapy ganciclovir is given to all patients at risk of HCMV disease from engraftment up to 3-4 months post transplantation. Each strategy has advantages and disadvantages and there is no evidence for the superiority of one over the other since the overall survival is the same and the incidence of death from HCMV disease is similar. PERSPECTIVES: The use of more sensitive tests such as HCMV PCR or antigenemia may improve the outcome but probably will not eradicate all HCMV disease. Future possible strategies could include adoptive transfer of CD8+ HCMV-specific cytotoxic T lymphocytes clones derived from the donor marrow or boosting donor or patient immunity using subunit anti-HCMV vaccines such as gB or pp65. (+info)

Antiviral therapy for neonatal herpes simplex virus: a cost-effectiveness analysis. (5/1121)

Each year, about 1,600 infants in the United States are infected with neonatal herpes simplex virus. We conducted a cost-effectiveness analysis of antiviral drug therapy (acyclovir) for three forms of herpes simplex virus infection: skin, ear, and mouth (SEM), central nervous system (CNS), and disseminated multiorgan (DIS) disease. Five levels of patient outcomes were examined (normal, mild, moderate, severe, dead). We obtained information on disease occurrence and survival from clinical trials and historical reviews of untreated newborns. We considered approaches for treating all or any of the forms of the disease and compared them with no use of antiviral drugs. The main measure of effectiveness was lives saved, including those of descendants of survivors. Costs were measured from a societal perspective and included direct medical costs, institutional care, and special education. We used a discount rate of 3% and valued dollars at 1995 levels. We also considered the perspective of a managed care organization. From a societal viewpoint relative to no treatment, antiviral therapy for SEM resulted in a gain of 0.8 lives and a cost reduction of $78,601 per case. For the treatment of CNS and DIS disease, antiviral therapy saved more lives but at increased cost, with respective marginal costs per additional life saved of $75,125 and $46,619. From a managed care perspective, antiviral therapy is more cost-effective than from a societal viewpoint because costs of institutional care and special education are not the responsibility of managed care organizations. Development of at-home therapies will further improve the cost-effectiveness of antiviral therapy for neonatal herpes simplex virus infection. (+info)

Intravenous penciclovir for treatment of herpes simplex infections in immunocompromised patients: results of a multicenter, acyclovir-controlled trial. The Penciclovir Immunocompromised Study Group. (6/1121)

The efficacy and safety of penciclovir (PCV) for the treatment of herpes simplex virus (HSV) infections in immunocompromised (IC) patients were studied in a double-blind, acyclovir (ACV)-controlled, multicenter study. A total of 342 patients with mucocutaneous HSV infections received 5 mg of PCV per kg every 12 or 8 h (q12h or q8h) or 5 mg of ACV per kg q8h, beginning within 72 h of lesion onset and continuing for up to 7 days. The mean age of the patients was 49 years; 94% were white and 52% were female. The main reasons for their IC states were hematologic disorder (63%) and transplant plus hematologic disorder (16%). Clinical and virological assessments were performed daily during the 7-day treatment and then every other day until lesion healing. The primary efficacy parameter addressed new lesion formation. Secondary end points focused on viral shedding, healing, and pain. Approximately 20% of patients in each treatment group developed new lesions during therapy; thus, equivalence with ACV (defined prospectively) was demonstrated for both q12h and q8h PCV regimens. For all three treatment groups, the median time to the cessation of viral shedding was 4 days and the median time to complete healing was 8 days; there were no statistically significant differences in the rates of complete healing or the cessation of viral shedding when the results for PCV q12h and q8h were compared with those for ACV q8h. In addition, there was no statistically significant difference between PCV q12h or q8h, compared with ACV q8h, for the resolution of pain. PCV was well tolerated, with an adverse event profile comparable to that of ACV. In conclusion, PCV q12h is a well-tolerated and effective therapy for mucocutaneous HSV infection in IC patients and offers a reduced frequency of dosing compared with ACV q8h. (+info)

Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group. (7/1121)

BACKGROUND: Cytomegalovirus (CMV) disease is a major complication of organ transplantation. We hypothesized that prophylactic treatment with valacyclovir would reduce the risk of CMV disease. METHODS: A total of 208 CMV-negative recipients of a kidney from a seropositive donor and 408 CMV-positive recipients were randomly assigned to receive either 2 g of valacyclovir or placebo orally four times daily for 90 days after transplantation, with the dose adjusted according to renal function. The primary end point was laboratory-confirmed CMV disease in the first six months after transplantation. RESULTS: Treatment with valacyclovir reduced the incidence or delayed the onset of CMV disease in both the seronegative patients (P<0.001) and the seropositive patients (P=0.03). Among the seronegative patients, the incidence of CMV disease 90 days after transplantation was 45 percent among placebo recipients and 3 percent among valacyclovir recipients. Among the seropositive patients, the respective values were 6 percent and 0 percent. At six months, the incidence of CMV disease was 45 percent among seronegative recipients of placebo and 16 percent among seronegative recipients of valacyclovir; it was 6 percent among seropositive placebo recipients and 1 percent among seropositive valacyclovir recipients. At six months, the rate of biopsy-confirmed acute graft rejection in the seronegative group was 52 percent among placebo recipients and 26 percent among valacyclovir recipients (P=0.001). Treatment with valacyclovir also decreased the rates of CMV viremia and viruria, herpes simplex virus disease, and the use of inpatient medical resources. Hallucinations and confusion were more common with valacyclovir treatment, but these events were not severe or treatment-limiting. The rates of other adverse events were similar among the groups. CONCLUSIONS: Prophylactic treatment with valacyclovir is a safe and effective way to prevent CMV disease after renal transplantation. (+info)

Long term neurological outcome of herpes encephalitis. (8/1121)

Twenty eight children with herpes simplex encephalitis were followed up for a mean of 5.5 years. Two children died and 26 survived, of whom 16 were left with no neurological sequelae and 10 had persistent neurological sequelae. Mean (SD) Glasgow coma score was significantly lower in the patients with neurological sequelae (7.7 (1.5)) and the patients who died (4.5 (0.7)), compared with the patients without neurological sequelae (11 (1.7)). (+info)

9. ACYCLOVIR 10. ADENOSINE 11. ADRENOCORTICOTROPHIC HORMONE (ACTH) 12. ALENDRONATE SODIUM 13. ALLOPURINOL ...

https://en.wikipedia.org/wiki/Schedule_H

Such drugs include other aminoglycosides; the antiviral acyclovir; the antifungal amphotericin B; the antibiotics bacitracin, ...

https://en.wikipedia.org/wiki/Amikacin

Aciclovir. Antiretrovirals[edit]. Nucleoside/nucleotide reverse transcriptase inhibitors[edit]. *Abacavir (ABC). *Lamivudine ( ...

https://en.wikipedia.org/wiki/List_of_World_Health_Organization_Essential_Medicines

aciclovir trials in the late 1980s.[106] The lower toxicity and ease of administration over vidarabine has led to aciclovir ... Several antiviral drugs are effective for treating herpes, including aciclovir (acyclovir), valaciclovir, famciclovir, and ... aciclovir seems to inhibit antibody response, and newborns on aciclovir antiviral treatment experienced a slower rise in ... Aciclovir was the first discovered and is now available in generic.[61] Valaciclovir is also available as a generic[62] and is ...

https://en.wikipedia.org/wiki/Herpes

Related antiviral drugs Aciclovir Valacyclovir, a prodrug form of aciclovir Famciclovir, an analogue of Penciclovir with ... It is taken orally once daily, in contrast to aciclovir, valaciclovir and other antivirals. A study has found that it is more ... 5246-8. ISBN 978-3-85200-181-4. "Brivudin (Zostex) besser als Aciclovir (Zovirax a.a.)?". Arznei-telegramm (in German). 5/2007 ... effective than aciclovir, but this has been disputed because of a possible conflict of interest on part of the study authors. ...

https://en.wikipedia.org/wiki/Brivudine

Acyclovir, steroids and therapeutic plasma exchange have been tried; one report suggests that the latter is more effective than ...

https://en.wikipedia.org/wiki/Hopkins_syndrome

Systemic aciclovir facilitates the early control of HZO lesions. James, William D.; Berger, Timothy G.; et al. (2006). Andrews ... Treatment is usually with antivirals such as aciclovir orally. Topical steroids and cycloplegics for several months. ...

https://en.wikipedia.org/wiki/Herpes_zoster_ophthalmicus

One review found that antivirals (such as aciclovir) are ineffective in improving recovery from Bell's palsy beyond steroids ... prednisone and acyclovir). Other research, however, identifies HSV-1 in only 31 cases (18 percent), herpes zoster (zoster sine ... "Early treatment with prednisolone or acyclovir in Bell's palsy". New England Journal of Medicine. 357 (16): 1598-607. doi ...

https://en.wikipedia.org/wiki/Bell

For herpes the treatment of choice is aciclovir.[23]. Surgical management is indicated where there is extremely increased ...

https://en.m.wikipedia.org/wiki/Viral_meningitis

"Acyclovir". The American Society of Health-System Pharmacists. Archived from the original on 2015-01-05. Retrieved Jan 1, 2015. ... The antiviral drug acyclovir, often used in herpes treatment, and the anti-HIV drug abacavir, are structurally similar to ...

https://en.m.wikipedia.org/wiki/Guanosine

... is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir ... Aciclovir is selectively converted into a monophosphate form by viral thymidine kinase, which is far more effective (3000 times ... Aciclovir, the active metabolite of valaciclovir, is active against most species in the herpesvirus family. In descending order ... Common adverse drug reactions (≥1% of people) associated with valaciclovir are the same as for aciclovir, its active metabolite ...

https://en.m.wikipedia.org/wiki/Valaciclovir

S01AD03 Aciclovir. S01AD05 Interferon. S01AD06 Vidarabine. S01AD07 Famciclovir. S01AD08 Fomivirsen. S01AD09 Ganciclovir. S01AX ...

https://ko.wikipedia.org/wiki/ATC_코드_S01

... acyclovir,[33] simvastatin,[34][35] xibornol,[36] silymarin,[37][38] alpha-asarone,[39] enilconazole,[19] puerarin (an ... Patel D; Sawant KK (December 2007). "Oral bioavailability enhancement of acyclovir by self-microemulsifying drug delivery ...

https://en.wikipedia.org/wiki/Self-microemulsifying_drug_delivery_system

... acyclovir, which was the first selective and effective drug of its kind).[25] Most of Elion's early work came from the use and ... acyclovir (ACV), used in the treatment of herpes infection.[3] ... Acyclovir (Zovirax), for viral herpes.[19]. *Nelarabine for ... "Developing the Purine Nucleoside Analogue Acyclovir: the Work of Gertrude B. Elion". J. Biol. Chem. 283 (19): e11. Retrieved ...

https://en.wikipedia.org/wiki/Gertrude_B._Elion

Multimedia: Aciclovir. *Identifikadoreak. *LCCN: sh88002652. *Hiztegiak eta entziklopediak. *Britannica: url. *Medikuntzako ...

https://eu.wikipedia.org/wiki/Aziklobir

acyclovir trials in the late 1980s.[101] The lower toxicity and ease of administration over vidarabine has led to acyclovir ... acyclovir seems to inhibit antibody response, and newborns on acyclovir antiviral treatment experienced a slower rise in ... Acyclovir was the first discovered and is now available in generic.[56] Valacyclovir is also available as a generic[57] and is ... "Acyclovir for treating primary herpetic gingivostomatitis". Cochrane Database Syst Rev (4): CD006700. doi:10.1002/14651858. ...

https://en.m.wikipedia.org/wiki/Herpes_simplex

Intravenous aciclovir, can be used to prevent viral replication, and in the event of persistent lymphocytic pleocytosis, higher ... Since herpes infections often lead to pleocytosis, aciclovir and valacyclovir are commonly prescribed. When pleocytosis is the ... doses of aciclovir can also be taken. Studies have shown this treatment combined with valacyclovir to be effective in combating ...

https://en.wikipedia.org/wiki/Lymphocytic_pleocytosis

Aciclovir is one of the oldest and most frequently prescribed antiviral drugs.[205] Other antiviral drugs in use target ... This is called DNA chain termination.[204] Examples of nucleoside analogues are aciclovir for Herpes simplex virus infections ... Mindel A, Sutherland S. Genital herpes - the disease and its treatment including intravenous acyclovir. Journal of ... The structure of the DNA base guanosine and the antiviral drug acyclovir ...

https://en.wikipedia.org/wiki/Virus_structure

Antiviral drugs such as acyclovir have been tried during the terminal phase of the disease. Cyclophosphamide and prednisone ...

https://en.wikipedia.org/wiki/Chédiak–Higashi_syndrome

If aciclovir by mouth is started within 24 hours of rash onset, it decreases symptoms by one day but has no effect on ... Infection in otherwise healthy adults tends to be more severe.[54] Treatment with antiviral drugs (e.g. aciclovir or ... There has also been speculation that continuous dosing of aciclovir by mouth for a period of time can eradicate VZV from the ... complication rates.[49][50] Use of aciclovir therefore is not currently recommended for individuals with normal immune function ...

https://en.wikipedia.org/wiki/Chickenpox

Acyclovir (Zovirax) - viiruslike herpesetüvede raviks. Tunnustus[muuda , muuda lähteteksti]. *1988 - Nobeli meditsiiniauhind ...

https://et.wikipedia.org/wiki/Gertrude_Elion

In the acyclovir-resistant HSV (PAAr5), a small peptide inhibitor BILD 1633 has been reported to be 5 to 10 times more potent ... A combination therapy approach (BILD 1633 and acyclovir) is more effective to heal topical lesions in mice. These data suggest ... "Antiviral activity of a selective ribonucleotide reductase inhibitor against acyclovir-resistant herpes simplex virus type 1 in ...

https://en.wikipedia.org/wiki/Ribonucleotide_reductase

The significant advantage of valaciclovir over aciclovir is its dosing of only 3 times/day (compared with aciclovir's 5 times/ ... In people who are at a high risk for repeated attacks of shingles, five daily oral doses of aciclovir are usually effective.[24 ... Whitley RJ, Weiss H, Gnann JW, Tyring S, Mertz GJ, Pappas PG, Schleupner CJ, Hayden F, Wolf J, Soong SJ (1996). "Acyclovir with ... A recent trial comparing aciclovir with its prodrug, valaciclovir, demonstrated similar efficacies in treating this form of the ...

https://fa.wikipedia.org/wiki/زونا?match=en

October 2007). "Early treatment with prednisolone or acyclovir in Bell's palsy". The New England Journal of Medicine. 357 (16 ... One review found that antivirals (such as aciclovir) are ineffective in improving recovery from Bell's palsy beyond steroids ...

https://en.m.wikipedia.org/wiki/Bell's_palsy

Done Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients PMID 27841441 ...

https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Medicine/Cochrane/Cochrane_Review_List/Musculoskeletal,_Oral,_Skin_and_Sensory

His group was one of the first to show that treating patients with the antiviral acyclovir can prevent genital and oral herpes ... Working on the then-current hypothesis that the syndrome might be caused by EBV, he started a clinical trial of acyclovir ...

https://en.wikipedia.org/wiki/Stephen_Straus

... with topical antiviral drugs such as aciclovir. 22% of cases of angular cheilitis are due to irritants. Saliva contains ...

https://en.wikipedia.org/wiki/Angular_cheilitis

Herpes outbreaks should be treated with antiviral medications like Acyclovir, Valacyclovir, or Famcyclovir, each of which is ... recommended dosage for suppression therapy for recurrent outbreaks is 1,000 mg of valacyclovir once a day or 400 mg Acyclovir ...

https://en.wikipedia.org/wiki/Herpes_gladiatorum

Acyclovir and valacyclovir by mouth are effective in preventing recurrent herpes labialis if taken prior to the onset of any ... Effective antiviral medications include acyclovir and penciclovir, which can speed healing by as much as 10%.[17] Famciclovir ... valaciclovir and a mixture of acyclovir and hydrocortisone are similarly useful in treating outbreaks but may also help prevent ...

https://en.wikipedia.org/wiki/Cold_sore

Antiviral medications, including acyclovir, are effective at controlling viral reactivation. Management of ensuing neuropathic ... Herpes reactivation is often treated with acyclovir, although evidence for its efficacy in controlling peripheral neurological ... Taylor M, Gerriets V (2020). Acyclovir. StatPearls. StatPearls Publishing. PMID 31194337. Johnson RW, Alvarez-Pasquin MJ, Bijl ...

https://en.wikipedia.org/wiki/Neuritis

Acyclovir: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Take or use acyclovir until you finish the prescription, even if you feel better. If you stop taking acyclovir too soon or skip ... Before taking acyclovir,. *tell your doctor and pharmacist if you are allergic to acyclovir, valacyclovir (Valtrex), any other ... If you become pregnant while taking acyclovir, call your doctor.. *if you are taking acyclovir to treat genital herpes, you ...

https://medlineplus.gov/druginfo/meds/a681045.html

Acyclovir Topical: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Acyclovir cream is usually applied five times a day for 4 days. Acyclovir cream may be applied at any time during a cold sore ... Acyclovir cream and ointment are for use only on the skin. Do not let acyclovir cream or ointment get into your eyes, or inside ... Acyclovir cream should only be applied to skin where a cold sore has formed or seems likely to form. Do not apply acyclovir ...

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Congenital Abnormality Transmit Disease Advisory Committee Acyclovir Disease Treatment These keywords were added by machine and ...

https://link.springer.com/article/10.2165/00128415-199203890-00009

Acyclovir definition, a crystalline compound, C18H11N5O3, used as an antiviral drug in the treatment of herpes infections. See ... acyclovir. 1980-85; perhaps acyclo(guanosine) an earlier name for the compound (a-6 + cyclo- + guanosine a nucleotide) + vir(us ...

https://www.dictionary.com/browse/acyclovir

The acyclovir oral tablet is used to treat viral infections such as shingles, genital herpes, and chickenpox. This form is ... Acyclovir comes in several prescription forms, including an oral tablet. ... Highlights for acyclovir. *Acyclovir oral tablet is available as both a generic and a brand-name drug. Brand name: Zovirax. ... How to take acyclovir. This dosage information is for acyclovir oral tablet. All possible dosages and drug forms may not be ...

https://www.medicalnewstoday.com/articles/322401.php?sr

... acyclovir, herpes - Answer: The first outbreak is usually the worst. It will take a few days before it ... ... How fast should Acyclovir.... How fast should Acyclovir work?. Asked. 1 Aug 2014 by helpp_30. Updated. 24 November 2018 (8 ... pain, acyclovir, herpes. Details:. I was told that I have herpes yesterday, but I feel like I waited too long to go to the dr, ... Acyclovir - So I got diagnosed with genital herpes I am to take 5 pills a day but Im confused?. Updated 3 Oct 2017 • 2 answers ...

https://www.drugs.com/answers/fast-acyclovir-work-1313337.html

Aciclovir-induced acute kidney injury. Medicina Clinica 154: 36, No. 1, 10 Jan 2020. Available from: URL: http://doi.org/ ... Aciclovir. Reactions Weekly 1790, 12 (2020). https://doi.org/10.1007/s40278-020-74631-y ...

https://link.springer.com/article/10.1007%2Fs40278-020-74631-y

Do not use Acyclovir Cream if you are:. •. allergic to Acyclovir Cream or any of the ingredients in Acyclovir Cream. See the ... Each gram of Acyclovir Cream 5% contains 50 mg acyclovir in an aqueous cream base. Acyclovir Cream is supplied as follows:. •. ... The pKas of acyclovir are 2.27 and 9.25.. Each gram of Acyclovir Cream 5% contains 50 mg of acyclovir and the following ... Systemic absorption of acyclovir from Acyclovir Cream is minimal in adults.. The systemic absorption of acyclovir following ...

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=103f29b8-2c13-4917-a446-59d3246d48d1

Acyclovir pharmacokinetic parameters are summarized in Table 1.. Table 1. Acyclovir Pharmacokinetic Characteristics (Range) * ... Acyclovir was positive in 5 of the assays.. Acyclovir did not impair fertility or reproduction in mice (450 mg/kg/day, p.o.) or ... The pkas of acyclovir are 2.27 and 9.25.. The chemical name of acyclovir is 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H ... Acyclovir capsules are formulation for oral administration. Acyclovir is a white or almost white, crystalline powder with the ...

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e580b7e9-9060-43f5-9b58-33998078d7e4

Renal function after acyclovir intravenous injection.. Brigden D, Rosling AE, Woods NC. ... Plasma urea or creatinine was noted to be raised in 58 of 354 patients treated with intravenous acyclovir. This occurred after ... Animal studies indicate that the impairment of renal function associated with high bolus injections of acyclovir is due to ... intravenous bolus injection of high dosages of acyclovir but the risk was considerably reduced by slow intravenous infusion of ...

https://www.ncbi.nlm.nih.gov/pubmed/6285711?dopt=Abstract

Acyclovir Suspension). Includes indications, proper use, special instructions, precautions, and possible side effects. ... Cold Sores acyclovir, Valtrex, valacyclovir, famciclovir, tetracaine topical, More.... Herpes Simplex acyclovir, Abreva, ... Herpes Simplex - Congenital acyclovir, More.... Herpes Simplex, Suppression acyclovir, Valtrex, valacyclovir, lysine, ... If you are taking Zovirax (acyclovir suspension) for an infection that came back, start Zovirax (acyclovir suspension) as soon ...

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Cymex ultra cream contains the active ingredient aciclovir, which is an antiviral medicine used to treat infections with the ... Cymex ultra (aciclovir). Cymex ultra cream contains the active ingredient aciclovir, which is an antiviral medicine used to ... Aciclovir is converted to a more active form inside cells of the body that are infected with herpes simplex. The activated ... This aciclovir cream is designed for the treatment of herpes simplex infections of the lips (cold sores). The cream should be ...

https://www.netdoctor.co.uk/medicines/mouth-teeth/a8498/cymex-ultra-aciclovir/

Acyclovir will not cure herpes, but it can lessen the symptoms of the infection. Acyclovir is used to treat infections caused ... Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. ... What is acyclovir?. Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. Acyclovir ... What other drugs will affect acyclovir?. Acyclovir can harm your kidneys. This effect is increased when you also use certain ...

https://www.rexhealth.com/rh/health-library/document-viewer/?id=d00001a1

Acyclovir for uncomplicated chickenpox?. BMJ 1993; 306 doi: https://doi.org/10.1136/bmj.306.6890.1478-c (Published 29 May 1993) ...

http://www.bmj.com/content/306/6890/1478.3

... acyclovir sodium injection, solution), including warnings and precautions, directions, and the names of other drugs and ...

https://www.healthgrades.com/drugs/acyclovir

Find treatment reviews for Acyclovir from other patients. Learn from their experiences about effectiveness, side effects and ... Showing 3 of 15 patient evaluations for Acyclovir Previous page 1 2 3 4 5 Next page ...

https://www.patientslikeme.com/treatment/acyclovir?page=5&size=3

Acyclovir will not cure herpes, but it can lessen the symptoms of the infection. Acyclovir is used to treat infections caused ... Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. ... What is acyclovir?. What is acyclovir?. Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in ... What other drugs will affect acyclovir?. What other drugs will affect acyclovir?. Acyclovir can harm your kidneys, especially ...

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... Learn about the reported side effects, related class drugs, and ... ACYCLOVIR (ay SYE kloe veer) is an antiviral medicine. It is used to treat or prevent infections caused by certain kinds of ...

https://www.cvs.com/drug/acyclovir/oral-tablet/400mg

Acyclovir Oral capsule drug summary. Find medication information including related drug classes, side effects, patient ... ACYCLOVIR (ay SYE kloe veer) is an antiviral medicine. It is used to treat or prevent infections caused by certain kinds of ... an unusual or allergic reaction to acyclovir, ganciclovir, valacyclovir, other medicines, foods, dyes, or preservatives. - ...

https://www.cvs.com/drug/acyclovir

The combination of acyclovir and hydrocortisone topical (for the... ... Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus so that the body can fight off the infection ... What is acyclovir and hydrocortisone topical?. Acyclovir is an antiviral drug. It slows the growth and spread of the herpes ... What is the most important information I should know about acyclovir and hydrocortisone topical?. Acyclovir and hydrocortisone ...

https://www.rexhealth.com/rh/health-library/document-viewer/?id=d07717a1

Acyclovir. Descriptions. Acyclovir belongs to the family of medicines called antivirals. Antivirals are used to treat ... Topical acyclovir is used to treat the symptoms of herpes simplex virus infections of the skin, mucous membranes, and genitals ... Topical acyclovir may also be used for other conditions as determined by your doctor. ... sex organs). Although topical acyclovir will not cure herpes simplex, it may help relieve the pain and discomfort and may help ...

https://www.mayoclinic.org/drugs-supplements/acyclovir-topical-route/description/drg-20061579

Acyclovir (Ophthalmic) - Last updated on May 8, 2021. All rights owned and reserved by Memorial Sloan Kettering Cancer Center. ...

https://www.mskcc.org/cancer-care/patient-education/acyclovir-ophthalmic

A prenatal exposure to acyclovir is defined as inadvertent or intentional use of oral or intravenous acyclovir at any time ... To assess the outcomes of pregnancies exposed to acyclovir, the Acyclovir in Pregnancy Registry was established on June 1, 1984 ... acyclovir administered intravenously is indicated. Among pregnant women without life-threatening disease, systemic acyclovir ... Acyclovir is available as a prescription medication and is used most commonly in its oral form to treat genital herpes; it is ...

https://www.cdc.gov/mmWr/preview/mmwrhtml/00022071.htm

Aciclovir is used for the treatment of herpes simplex virus infections, varicella zoster (chickenpox) and herpes zoster ( ... shingles). Aciclovir has also been investigated for the treatment of herpes labialis applied using an iontophoretic device. ... Acyclovir. Acyclovir (50 mg/1g). Ointment. Topical. OASIS TRADING. 2018-11-15. Not applicable. US. ... One may consider aciclovir to be a prodrug as it is metabolized to more active compounds. Aciclovir is selective and low in ...

https://www.drugbank.ca/drugs/DB00787

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Find user ratings and reviews for acyclovir oral on WebMD including side effects and drug interactions, medication ... The Acyclovir took care of my shingles, but the treatment put me in grave danger. I read a review on this website about another ... Once in the ER, I tried to tell the dr and nurses about the Acyclovir Id just begun that day. No one was listening. The ER doc ... I tried to bring up the Acyclovir again, but he clearly ignored me and what I was trying to tell him. I decided to go home. ...

https://www.webmd.com/drugs/drugreview-941-acyclovir-oral.aspx?drugid=941&

Acyclovir Ophthalmic Ointment) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and ... Acyclovir was tested in 16 in vitro and in vivo genetic toxicity assays. Acyclovir was found to be negative in the Ames test, ... The pkas of acyclovir are 2.52 and 9.35.. The chemical name of acyclovir is 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]6H- ... Acyclovir is an antiviral drug [see Microbiology].. Pharmacokinetics. It has not been possible to detect acyclovir ...

https://www.rxlist.com/avaclyr-drug.htm

Acyclovir and Hydrocortisone - Last updated on December 4, 2020. All rights owned and reserved by Memorial Sloan Kettering ...

https://www.mskcc.org/cancer-care/patient-education/acyclovir-and-hydrocortisone

Use of Acyclovir. Dec 26, 2004. Six months ago my T cells were at 360 and my doctor said I would begin meds by the end of the ... As you know, Acyclovir is prescribed for herpes, but I have noticed it mentioned occasionally in the HIV literature. My ... But using acyclovir as a general preventive strategy to favorably alter the natural history of HIV infection is not recommended ... Actually, in the pre-HAART era I prescribed acyclovir for the majority of my patients (partly because the HIV meds did so ...

http://www.thebody.com/Forums/AIDS/Meds/Q161857.html

Acyclovir buccal tablet is used to treat the symptoms of herpes simplex virus infection on the lips and around the mouth (cold ...

https://www.mayoclinic.org/drugs-supplements/acyclovir-buccal-mucosa-route/description/drg-20060911

Acyclovir is also sometimes used to prevent outbreaks of genital herpes in people who are infected with the virus. (medlineplus.gov)
Acyclovir will not cure genital herpes and may not stop the spread of genital herpes to other people. (medlineplus.gov)
When acyclovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months. (medlineplus.gov)
Acyclovir ointment is used to treat first outbreaks of genital herpes (a herpes virus infection that causes sores to form around the genitals and rectum from time to time) and to treat certain types of sores caused by the herpes simplex virus in people with weak immune systems. (medlineplus.gov)
Acyclovir does not cure cold sores or genital herpes, does not prevent outbreaks of these conditions, and does not stop the spread of these conditions to other people. (medlineplus.gov)
Do not apply acyclovir cream to any unaffected skin, or to genital herpes sores. (medlineplus.gov)
If you have genital herpes, Zovirax (acyclovir suspension) will not stop it from spreading. (drugs.com)
Acyclovir and hydrocortisone will not prevent the spread of genital herpes. (rexhealth.com)
Intravenous aciclovir is effective to treat severe medical conditions caused by different species of the herpes virus family, including severe localized infections of herpes virus, severe genital herpes, chickenpox and herpesviral encephalitis. (wikipedia.org)
Classified as a Category B drug, the CDC and others have declared that during severe recurrent or first episodes of genital herpes, aciclovir may be used. (wikipedia.org)
The purpose of this study is to determine if acyclovir episodic treatment has an effect in ulcer healing and if it should be added to the syndromic management of genital ulcer disease. (clinicaltrials.gov)
This study will help answer the question if acyclovir therapy for herpes should be added into the syndromic management of genital ulcer disease. (clinicaltrials.gov)
Acyclovir injection is used to treat severe infections caused by herpes viruses, including severe forms of genital herpes, shingles, herpes encephalitis (swelling of the brain), and herpes infections in people with other diseases that weaken the immune system. (adventisthealthcare.com)
En la práctica, el aciclovir solamente es utilizado en el tratamiento de la varicela, del herpes zóster y herpes genital y labial. (cysers.info)
prevención, herpes genital (siendo eficaz en el primer período de herpes genital), herpes zoster en pacientes Para el tratamiento del herpes zóster: 4 comprimidos de mg, 5 veces al día a intervalos de 4 horas. (cysers.info)
Acyclovir topical ointment is used to treat genital herpes lesions. (everydayhealth.com)
In clinical trials of initial genital herpes infections, acyclovir ointment 5% has shown a decrease in healing time and, in some cases, a decrease in duration of viral shedding and duration of pain. (bioportfolio.com)
Aciclovir is usually prescribed for the treatment of herpes simplex virus infections including genital herpes, the prevention of recurrences of viral infections, and the treatment of chickenpox infections. (pharmacy2u.co.uk)
In another study, 20 immunocompetent patients with recurrent genital herpes simplex infections given acyclovir capsules in doses of 800 mg every 6 hours, 4 times daily for 5 days, the mean steady-state peak and trough concentrations were 1.4 g/mL (0.66 to 1.8 g/mL) and 0.55 g/mL (0.14 to 1.1 g/mL). (rxmed.com)
The results of clinical studies suggest that some patients with recurrent genital herpes may derive clinical benefit from the administration of oral acyclovir if taken at the first sign of an impending episode. (rxmed.com)
Aside from these topical medications, Acyclovir tablets, capsules and liquid can also be used to treat certain herpes simplex infections which may include genital herpes. (coldsoreproof.com)
For conditions such as recurrent cold sores or genital herpes, an Acyclovir dose of 400 milligrams twice a day for up to about 12 months is usually recommended. (coldsoreproof.com)
Acyclovir is also helpful in reducing the risks of transmitting genital herpes, although the drug does not absolutely prevent transmission. (accessrx.com)
Treatment of recurrent genital herpes simplex infections with oral acyclovir. (nih.gov)
Two hundred fifty patients were entered into a multicenter trial to evaluate the efficacy and toxicity of orally administered acyclovir for treatment of recurrent genital herpes. (nih.gov)
Oral acyclovir shortens the duration of virus shedding and the duration of lesions in patients with recurrent genital herpes. (nih.gov)
USES: This medication is acyclovir price walmart used to treat the first outbreak of genital herpes infection. (pimaair.org)
Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chicken pox. (tsrocks.com)
Aciclovir is a treatment to help combat the symptoms of genital herpes available through the ChemistDirect.co.uk Online Doctor Service. (chemistdirect.co.uk)
Aciclovir provides treatment for genital herpes. (chemistdirect.co.uk)
Do not acyclovir have acyclovir any kind of acyclovir sex when you have ointment sores or other signs acyclovir of ointment genital herpes. (sportsrubbish.com)

Acyclovir oral tablet is a prescription drug that's available as the brand-name drug Zovirax. (medicalnewstoday.com)
If you have an allergy to acyclovir, valacyclovir , or any other part of Zovirax (acyclovir suspension). (drugs.com)
You must check to make sure that it is safe for you to take Zovirax (acyclovir suspension) with all of your drugs and health problems. (drugs.com)
Tell all of your health care providers that you take Zovirax (acyclovir suspension). (drugs.com)
If you are 65 or older, use Zovirax (acyclovir suspension) with care. (drugs.com)
You will need to talk about the benefits and risks of using Zovirax (acyclovir suspension) while you are pregnant. (drugs.com)
Use Zovirax (acyclovir suspension) as ordered by your doctor. (drugs.com)
Keep taking Zovirax (acyclovir suspension) as you have been told by your doctor or other health care provider, even if you feel well. (drugs.com)
If you are taking Zovirax (acyclovir suspension) for an infection that came back, start Zovirax (acyclovir suspension) as soon as you can. (drugs.com)
Use the measuring device that comes with Zovirax (acyclovir suspension). (drugs.com)
If there is none, ask the pharmacist for a device to measure Zovirax (acyclovir suspension). (drugs.com)
Very bad and sometimes deadly kidney problems have happened with Zovirax (acyclovir suspension). (drugs.com)
Very bad and sometimes deadly blood problems like thrombotic thrombocytopenic purpura / hemolytic uremic syndrome (TTP/HUS) have happened with Zovirax (acyclovir suspension) in some people. (drugs.com)
You should not use this medication if you are allergic to acyclovir (Zovirax) or hydrocortisone. (rexhealth.com)
Acyclovir (Zovirax Registered *), an antiviral drug effective in the treatment of herpes simplex infection, was approved by the Food and Drug Administration (FDA) in 1984. (cdc.gov)
Zovirax, the brand name for acyclovir by GlaxoSmithKline, is one of the two sole FDA-approved cold sore prescription medications. (coldsoreproof.com)
Side Note: Acyclovir is the generic name for Zovirax and both will be used alternately in the rest of the article. (coldsoreproof.com)
Zovirax is effective in cold sores mainly because Acyclovir has the ability to prevent the herpes simplex virus from replicating and thereby promoting faster healing. (coldsoreproof.com)
Zovirax cold sore cream (Acyclovir cream) is most commonly used and prescribed by doctors for cold sores. (coldsoreproof.com)
Acyclovir is commonly known by its brand name, Zovirax. (accessrx.com)
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Description, zovirax is the brand name for acyclovir, a synthetic nucleoside analogue active against herpes viruses. (sportsrubbish.com)
They asked if prednisolone 25 mg twice daily for 10 days or acyclovir (Zovirax) 400 mg five times daily for 10 days, alone or in combination, could improve the rate of recovery from Bell palsy. (aafp.org)

Do not let acyclovir cream or ointment get into your eyes, or inside your mouth or nose, and do not swallow the medication. (medlineplus.gov)
Acyclovir and hydrocortisone topical may also be used for purposes not listed in this medication guide. (rexhealth.com)
Aciclovir (ACV), also known as acyclovir, is an antiviral medication. (wikipedia.org)
Studies also indicate that taking Acyclovir for shingles, along with another type of medication, could even be more effective. (wisegeek.com)
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Though Acyclovir is generally a prescription medication, they are widely distributed all over the Internet for the millions of cold sore and fever blister sufferers all over the world. (coldsoreproof.com)
You most likely have heard of the medication Acyclovir for cold sores. (coldsoreproof.com)
As you know, the herpes simplex is the causative virus that causes cold sore outbreaks and the anti-viral property in Acyclovir medication makes it effective in fighting against it. (coldsoreproof.com)
Many people can attest to the effectiveness of Acyclovir prescription medication to treat their cold sore outbreak faster. (coldsoreproof.com)
In part B, fewer acyclovir recipients formed new lesions during the study medication period than did placebo recipients. (nih.gov)
However, you should not flush this acyclovir cream medication down the toilet. (sportsrubbish.com)
These factors may affect how acyclovir you should use this medication. (sportsrubbish.com)
Medication abortion early in dosing acyclovir 400 mg the perioperative period. (cadasb.org)

Acyclovir is also sometimes used to treat eczema herpeticum (a skin infection caused by the herpes virus) to treat and prevent herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV), and to treat oral hairy leukoplakia (condition that causes hairy white or gray-colored patches on the tongue or inside of the cheek). (medlineplus.gov)
Acyclovir is used to treat viral infections. (medicalnewstoday.com)
Cymex ultra cream contains the active ingredient aciclovir, which is an antiviral medicine used to treat infections with the herpes virus. (netdoctor.co.uk)
This aciclovir cream is designed for the treatment of herpes simplex infections of the lips (cold sores). (netdoctor.co.uk)
Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir and hydrocortisone topical. (rexhealth.com)
For severe HSV infections (especially disseminated HSV), IV aciclovir may also be used. (wikipedia.org)
Topical acyclovir is used to treat the symptoms of herpes simplex virus infections of the skin, mucous membranes, and genitals (sex organs). (mayoclinic.org)
However, inadvertent pregnancy exposures to acyclovir were expected to occur among women in whom treatment had been indicated for preexisting herpes simplex infections. (cdc.gov)
Aciclovir is used for the treatment of herpes simplex virus infections, varicella zoster (chickenpox) and herpes zoster (shingles). (drugbank.ca)
Unless you have recurrent herpes infections that are breaking through on daily acyclovir there is no good reason to increase the dosage. (thebody.com)
Patients were given oral acyclovir for at least 6 months prior to surgery to deactivate the infections and continued a prophylactic postoperative course for 6 to 33 months. (aao.org)
Dipeptide and tripeptide ester derivatives of acyclovir and its analogs are disclosed which are useful to treat herpes virus infections. (ideaconnection.com)
Neonates diagnosed with HSV-1 or HSV-2 at least than or equal to 28 days of age as evidenced by infections limited to the skin, eye and mouth with normal CNS and treated with intravenous acyclovir therapy. (clinicaltrials.gov)
Two clinical pharmacology studies were performed with acyclovir ointment 5% in immunocompromised adults at risk of developing mucocutaneous Herpes simplex virus infections or with localized varicella-zoster infections. (bioportfolio.com)
Aciclovir est utilisé pour traiter des infections virales comme l'herpès labial, pour arrêter la croissance du virus de l'herpès simplex, le virus varicelle-zona (causées par la varicelle et du zona), virus d'Epstein Barr (causés par la fièvre glandulaire), et dans une moindre mesure à cytomégalovirus (CMV). (blogarama.com)
Acyclovir is used to treat herpes infections in their many manifestations. (accessrx.com)
With Aciclovir you can treat herpes as well as other viral infections caused by the virus, including shingles. (chemistdirect.co.uk)
It is also used ointment to treat non-life-threatening herpes acyclovir infections of the skin acyclovir and around the mouth ( cold sores ) in people with a weakened immune system. (sportsrubbish.com)
Adverse Effects 10, acyclovir burning/stinging (30) 1-10 Pruritus (4) 1 Dry lips ( 1) Rash (0.3) Frequency Not Defined Angioedema Vulvitis Previous Next: Warnings Contraindications Hypersensitivity Cautions Not recommended ointment for recurrent infections Use caution in immunocompromised patients Avoid physical contact. (sportsrubbish.com)

If you stop taking acyclovir too soon or skip doses, your infection may not be completely treated or may become more difficult to treat. (medlineplus.gov)
However, if it is almost time for the acyclovir dosage ointment next dose, skip the ointment missed dose and continue your regular dosing schedule. (sportsrubbish.com)
If acyclovir it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. (sportsrubbish.com)

tell your doctor and pharmacist if you are allergic to acyclovir, valacyclovir (Valtrex), any other medications, milk proteins, or any of the ingredients in acyclovir products. (medlineplus.gov)
Acyclovir Cream is contraindicated in patients with known hypersensitivity to acyclovir, valacyclovir or any component of the formulation. (nih.gov)
Free Pills With Every Order Compare prices, print coupons and get savings tips for Valacyclovir (Generic Valtrex) and acyclovir price walmart other Shingles, Herpes, and Cold Sores drugs at CVS, Walgreens, and other pharmacies. (pimaair.org)
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A study showed that antiviral drugs, such as acyclovir, valacyclovir and famcyclovir, helped to clear a herpes zoster (shingles) outbreak, but had no effect on the lingering pain caused by the virus (1). (prweb.com)

This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue. (nih.gov)
In vitro , acyclovir triphosphate stops replication of herpes viral DNA. (nih.gov)
The greater antiviral activity of acyclovir against HSV compared to VZV is due to its more efficient phosphorylation by the viral TK. (nih.gov)
Resistance of HSV and VZV to acyclovir can result from qualitative and quantitative changes in the viral TK and/or DNA polymerase. (nih.gov)
While most of the acyclovir-resistant mutants isolated thus far from immunocompromised patients have been found to be TK-deficient mutants, other mutants involving the viral TK gene (TK partial and TK altered) and DNA polymerase have been isolated. (nih.gov)
The possibility of viral resistance to acyclovir should be considered in patients who show poor clinical response during therapy. (nih.gov)
The activated aciclovir works by blocking the action of a viral enzyme called DNA polymerase. (netdoctor.co.uk)
Valaciclovir and acyclovir act by inhibiting viral DNA replication, but as of 2016 there was little evidence that they are effective against Epstein-Barr virus, they are expensive, they risk causing resistance to antiviral agents, and (in 1% to 10% of cases) can cause unpleasant side effects. (wikipedia.org)
After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization. (cancer.gov)
Acyclovir will not treat a viral infection such as the common cold or flu. (adventisthealthcare.com)
To achieve maximal benefit from antiviral therapy, acyclovir must be initiated before widespread viral dissemination throughout the body or to significant replication within the central nervous system (CNS). (aappublications.org)
Although clinically significant viral resistance associated with the use of acyclovir ointment 5 has not been observed, this possibility exists. (sportsrubbish.com)

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Plasma urea or creatinine was noted to be raised in 58 of 354 patients treated with intravenous acyclovir. (nih.gov)

This occurred after intravenous bolus injection of high dosages of acyclovir but the risk was considerably reduced by slow intravenous infusion of the same dosage over one hour, with adequate hydration of the patient and adjustment of dosage in patients with preexisting impaired renal function. (nih.gov)
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What is the dosage of Acyclovir And Hydrocortisone? (medindia.net)

Aciclovir taken by mouth does not appear to decrease the risk of pain after shingles. (wikipedia.org)
Is acyclovir as effective as Valtrex in treating shingles? (healthboards.com)
How Effective Is Acyclovir for Shingles? (wisegeek.com)
Using Acyclovir for treatment of shingles has been approved by the U.S. Food and Drug Administration and other health agencies around the world. (wisegeek.com)
Using Acyclovir for shingles should begin as soon as the symptoms are noticed because effectiveness quickly diminishes after 72 hours from the onset of symptoms. (wisegeek.com)
The administration of Acyclovir for shingles is one of the most studied treatments in the world for the disease. (wisegeek.com)
The main benefit of using Acyclovir for shingles is that it reduces the pain associated with the illness. (wisegeek.com)
One of the other benefits of Acyclovir for shingles is that it reduces the overall duration of the outbreak. (wisegeek.com)
While the benefits of Acyclovir to fight shingles outbreaks are generally clear, the drug can be inconvenient and have side effects. (wisegeek.com)
My mom's doctor told her if someone thinks they have shingles, to get in under the 12-hour mark if possible, because Acyclovir is really at its best in that time frame. (wisegeek.com)

Dendritic keratitis occurred during oral acyclovir (ACV) therapy in a 60-year-old man. (unboundmedicine.com)
Identical to oral acyclovir suspens. (clinicaltrials.gov)
Identical to oral acyclovir suspension in appearance and taste. (clinicaltrials.gov)
Treatment of varicella (chickenpox) in immune competent patients with oral acyclovir reduced the total number of lesions, accelerated the progression of lesions to the crusted and healed stages, and decreased the number of residual hypopigmented lesions. (rxmed.com)

Acyclovir Cream is a herpes simplex virus (HSV) nucleoside analogue DNA polymerase inhibitor indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents 12 years of age and older. (nih.gov)
Acyclovir is a synthetic nucleoside analogue active against herpesviruses. (nih.gov)
Acyclovir is a synthetic purine nucleoside analogue with in vitro and in vivo inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2) and varicella-zoster virus (VZV). (nih.gov)
Aciclovir is a nucleoside analogue that mimics guanosine. (wikipedia.org)
XERESE contains acyclovir , a synthetic nucleoside analogue active against herpes viruses , and hydrocortisone, an anti-inflammatory corticosteroid , combined in a cream for topical administration. (rxlist.com)
Acyclovir, 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one, is a synthetic nucleoside analogue active against herpes viruses. (rxlist.com)

Acyclovir comes as a tablet, a capsule, and a suspension (liquid) to take by mouth. (medlineplus.gov)
Acyclovir oral tablet is available as both a generic and a brand-name drug. (medicalnewstoday.com)
Acyclovir is also available as a capsule, suspension, and buccal tablet you take by mouth. (medicalnewstoday.com)
Acyclovir oral tablet doesn't cause drowsiness but it can cause other side effects. (medicalnewstoday.com)
Acyclovir buccal tablet is used to treat the symptoms of herpes simplex virus infection on the lips and around the mouth (cold sores) in adults with normal immune systems. (mayoclinic.org)
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Usual Adult Dose for Herpes Simplex Labialis Immunocompetent host: Apply 50 mg (1 buccal tablet) as a single-dose to the upper gum region (canine fossa) Comments: -Tablet should be applied acyclovir within 1 hour after the onset of day prodromal symptoms. (silentbobspeaks.com)

Acyclovir belongs to a class of drugs called antivirals. (medicalnewstoday.com)
Clinical experience has identified no interactions resulting from topical or systemic administration of other drugs concomitantly with Acyclovir Cream. (nih.gov)
Buying prescription drugs from Internet drug stores have websites you may find helpful on Our Sites and third-party sites aciclovir pensa . (spiritofbaraka.com)
It is not likely that other drugs you take orally or inject will have an effect on topically applied acyclovir. (everydayhealth.com)
What other drugs will affect acyclovir and hydrocortisone topical? (pardeehospital.org)
Aglaia Koutsodimou and Giovanni Natile, "Reaction of cis - and trans -Dichlorotetra(Dimethylsulfoxide)Ruthenium(II) With the Antiviral Drug Acyclovir," Metal-Based Drugs , vol. 7, no. 6, pp. 325-334, 2000. (hindawi.com)
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Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let acyclovir your prescriber know if you use them. (sportsrubbish.com)

Methods: We plan an individually randomized double blind placebo-control trial of the WHO and US CDC recommended dose of 3-times daily acyclovir for a 5-day treatment course. (clinicaltrials.gov)
In 1 of these studies, which included 16 inpatients, the complete ointment or its vehicle were randomly administered in a dose of 1-cm strips (25 mg acyclovir) 4 times a day for 7 days to an intact skin surface area of 4.5 square inches. (bioportfolio.com)
Coombs RW, Collier AC, Chaloupka K, Corey L. Decreased HIV plasma titer in response to combined low-dose zidovudine and acyclovir therapy in CDC class IVA patients. (clinicaltrials.gov)
On hospital day 8, intravenous acyclovir therapy was initiated at a dose of 250 mg/m 2 body surface area every 8 hours. (annals.org)
Renal Dose Adjustments Oral: For CrCl 0 to day 10 one mL/min/1.73 m2 : -If normal dose is 200 mg acyclovir orally every 4 hours 5 times one a day: Reduce dose to 200 mg orally every 12 hours -If normal. (silentbobspeaks.com)

Topical acyclovir comes as a cream and an ointment to apply to the skin. (medlineplus.gov)
Use topical acyclovir exactly as directed. (medlineplus.gov)
Although topical acyclovir will not cure herpes simplex, it may help relieve the pain and discomfort and may help the sores (if any) heal faster. (mayoclinic.org)
Topical acyclovir may also be used for other conditions as determined by your doctor. (mayoclinic.org)
Treatment of erythema multiforme secondary to herpes simplex by prophylactic topical acyclovir. (bmj.com)
Kennedy C T , Leigh I M , Ridgway H A , Wansbrough-Jones M H , Brigden D . Treatment of erythema multiforme secondary to herpes simplex by prophylactic topical acyclovir. (bmj.com)

It is best to begin using acyclovir ointment as soon as possible after you experience the first symptoms of infection. (medlineplus.gov)
Clinical isolates of HSV and VZV with reduced susceptibility to acyclovir have been recovered from immunocompromised patients, especially with advanced HIV infection. (nih.gov)
The pharmacokinetics of acyclovir after oral administration have been evaluated in healthy volunteers and in immunocompromised patients with herpes simplex or varicella-zoster virus infection. (nih.gov)
Acyclovir and hydrocortisone topical will not cure or prevent herpes , but it can lessen the symptoms of the infection. (rexhealth.com)
Some physicians have reported intentional use of acyclovir during pregnancy for treatment of life-threatening herpes simplex infection. (cdc.gov)
But using acyclovir as a general preventive strategy to favorably alter the natural history of HIV infection is not recommended because it does not work. (thebody.com)
It remains an open question as to whether acyclovir monotherapy will favorably alter the natural history of HIV infection in persons that don't have herpes infection. (thebody.com)
Acyclovir will not cure herpes, but it can lessen the symptoms of the infection. (adventisthealthcare.com)
Use of acyclovir in infants and children in 6 common non-HSV infection-related diagnosis-related groups was characterized between 1999 and 2012 at 15 US pediatric hospitals by using the Pediatric Health Information System database. (aappublications.org)
Acyclovir is the drug of choice for local and disseminated herpes simplex infection in infants and children. (silentbobspeaks.com)

Common adverse drug reactions (≥1% of patients) associated with systemic aciclovir therapy (oral or IV) include nausea, vomiting, diarrhea, encephalopathy (with IV use only), injection site reactions (with IV use only) and headache. (wikipedia.org)
The risks of Acyclovir include nausea and vomiting, diarrhea and headaches among others. (wisegeek.com)
Fatigue · Caffeine · Nausea · Dry aciclovir tratamiento para zoster · Diarrhea · Hormone · Ejaculation aciclovir tratamiento para zoster Dancing · Sweating. (cysers.info)
People who take Acyclovir report side effects including nausea, dizziness, and drowsiness. (accessrx.com)

Each gram of Acyclovir Cream 5% contains 50 mg of acyclovir. (nih.gov)
Each gram of acyclovir ointment USP 5% contains 50 mg of acyclovir USP in a polyethylene glycol (PEG) base. (bioportfolio.com)

Acyclovir for uncomplicated chickenpox? (bmj.com)
The prophylactic use of acyclovir in chickenpox has not been established. (rxmed.com)

FDA pregnancy category B. Acyclovir and hydrocortisone topical is not expected to harm an unborn baby. (rexhealth.com)
Aciclovir is recommended by the CDC for treatment of varicella during pregnancy, especially during the second and third trimesters. (wikipedia.org)
To assess the outcomes of pregnancies exposed to acyclovir, the Acyclovir in Pregnancy Registry was established on June 1, 1984, by the manufacturer, in collaboration with CDC. (cdc.gov)
A prenatal exposure to acyclovir is defined as inadvertent or intentional use of oral or intravenous acyclovir at any time during pregnancy. (cdc.gov)
Editorial Note: Based on comparisons with birth defects surveillance data maintained by CDC, the registry findings summarized in this report indicate no increased risk for birth defects among infants born to women exposed to acyclovir during pregnancy (3). (cdc.gov)
A prospective epidemiologic registry of acyclovir use from 1984 to 1999 indicated that the occurrence rate of birth defects in women exposed to systemically administered acyclovir during the first trimester of pregnancy (period of organogenesis) approximated that found in the general population. (rxlist.com)
Less than when to take acyclovir during pregnancy at short, k􏰃 leukotriene receptor blockers. (imagenenaccion.org)
Pyrimethamine is symptomatically useful for evidence that patients with nicotinic-receptor-antagonist when to take acyclovir during pregnancy properties. (imagenenaccion.org)
Acyclovir in pregnancy registry: six years' experience. (rti.org)
The Acyclovir in Pregnancy Registry was established to gather data on prenatal exposure to acyclovir. (rti.org)

Acyclovir and hydrocortisone topical is not approved for use by anyone younger than 6 years old. (pardeehospital.org)

By blocking the action of DNA polymerase, aciclovir prevents the herpes virus from multiplying. (netdoctor.co.uk)
Acyclovir is a synthetic herpes simplex virus nucleoside analog DNA polymerase inhibitor. (rxlist.com)
XERESE, a combination of acyclovir, a herpes simplex virus deoxynucleoside analog DNA polymerase inhibitor, and hydrocortisone, a corticosteroid, is indicated for the early treatment of recurrent herpes labialis (cold sores) to reduce the likelihood of ulcerative cold sores and to shorten the lesion healing time in adults and children (6 years of age and older). (rxlist.com)
Acyclovir triphosphate is both an inhibitor of, and a substrate for, herpesvirus-specified DNA polymerase. (rxmed.com)
Although the cellular a-DNA polymerase in infected cells may also be inhibited by acyclovir triphosphate, this occurs only at concentrations of acyclovir triphosphate which are higher than those which inhibit the herpesvirus-specified DNA polymerase. (rxmed.com)

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Take or use acyclovir until you finish the prescription, even if you feel better. (medlineplus.gov)
Read this information before you start using acyclovir and each time you refill your prescription. (medlineplus.gov)
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Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to acyclovir explain any part you do not understand. (sportsrubbish.com)

Acyclovir is an antiviral agent (treats a virus). (mayoclinic.org)

Orally administered acyclovir in children less than 2 years of age has not yet been fully studied. (rxmed.com)
Some people use Acyclovir in the form of an ointment, and with this form of the drug, dizziness is less likely to be a problem, so drinking alcohol will have less of an effect than if the drug is taken orally. (accessrx.com)
Episodic (Intermittent) Therapy: Effective treatment requires therapy initiation acyclovir 400 mg within 1 day acyclovir of lesion onset or during the prodrome preceding an episode/recurrence 400 mg orally 3 times a day for 5 to 14 days. (silentbobspeaks.com)

Acyclovir Cream should only be applied on the affected external aspects of the lips and face in patients with herpes labialis. (nih.gov)
The effect of Acyclovir Cream has not been established in immunocompromised patients. (nih.gov)
In five double-blind, placebo-controlled trials, 1124 patients were treated with Acyclovir Cream and 1161 with placebo (vehicle) cream. (nih.gov)
Actually, in the pre-HAART era I prescribed acyclovir for the majority of my patients (partly because the HIV meds did so little). (thebody.com)
In some cases, Acyclovir may be more effective in treating older individuals, meaning those over the age of 60, than younger patients. (wisegeek.com)
If a corticosteroid is administered along with Acyclovir, the pain patients report can be reduced substantially. (wisegeek.com)
In this uncontrolled study, acyclovir was detected in the blood of 9 patients and in the urine of all patients tested. (bioportfolio.com)
Pharmacokinetics: The pharmacokinetics of acyclovir after oral administration have been evaluated in 6 clinical studies involving 110 adult patients. (rxmed.com)
Suppressive therapy of herpes genitalis with acyclovir should be considered only for severely affected patients. (rxmed.com)
A total of 186 patients are summarized, all of whom were treated with acyclovir. (aappublications.org)
Among patients with disseminated HSV disease treated with acyclovir at 30 mg/kg/d, mortality was associated with aspartate transaminase elevations of ≥10 times the upper limit of normal at the time of initiation of acyclovir therapy. (aappublications.org)
To compare the effect of zidovudine (AZT) given alone with the combination of AZT and acyclovir (ACV) on the human immunodeficiency virus (HIV) in persons infected with HIV, and to study the pharmacokinetics (how fast AZT reaches certain levels in blood and how long it remains), safety, and effectiveness of AZT given alone and in combination with ACV in treating HIV-infected patients. (clinicaltrials.gov)
Other conditions can contribute to the level of dizziness experienced by patients taking Acyclovir. (accessrx.com)
In both parts, patients received either acyclovir (200 mg) or placebo, five times daily for five days. (nih.gov)
Involuntarily carried out to 7-4 units/hour, those with rectal bleeding in patients with septic shock is defined as those seen following hyperventilation acyclovir suppression. (cadasb.org)
Overall, 551 patients were randomized using block randomization to receive acyclovir plus placebo, acyclovir plus prednisolone, prednisolone plus placebo, or placebo plus placebo within 72 hours of symptom onset. (aafp.org)

Read user comments about the side effects, benefits, and effectiveness of acyclovir oral. (webmd.com)
2) Why don't doctors in the field suggest that people take Acyclovir to see if they can delay the starting of treatments that might have strong side effects? (thebody.com)
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What are the possible side effects of acyclovir and hydrocortisone topical? (pardeehospital.org)
Other side effects of Acyclovir that should be reported to a physician right away include extreme fatigue, changes in heart rate, easy bruising or bleeding, dark or bloody urine, severe gastric pain, vision changes, seizures, or yellowing of the skin or the whites of the eyes. (accessrx.com)
The most common problem that can occur when a person taking Acyclovir drinks alcohol is an amplification of the dizziness and drowsiness that frequently occur as side effects of the drug. (accessrx.com)
People who drink while taking Acyclovir are more likely to experience side effects such as fainting or changes in vision. (accessrx.com)

For the Herpes Simplex Virus (HPV) take Aciclovir for at least 5 days, taking a 200mg at least 5 times a day. (chemistdirect.co.uk)

The pka's of acyclovir are 2.27 and 9.25. (nih.gov)
The pka's of acyclovir are 2.52 and 9.35. (rxlist.com)

Herpes simplex and varicella-zoster specified thymidine kinase transform acyclovir to its monophosphate which is then transformed by a number of cellular enzymes to acyclovir diphosphate and acyclovir triphosphate. (rxmed.com)

Renal function after acyclovir intravenous injection. (nih.gov)
What is the most important information I should know about acyclovir injection? (adventisthealthcare.com)
What should I discuss with my healthcare provider before using acyclovir injection? (adventisthealthcare.com)
How should I use acyclovir injection? (adventisthealthcare.com)
Store acyclovir injection at room temperature away from moisture and heat. (adventisthealthcare.com)
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Aciclovir has also been investigated for the treatment of herpes labialis applied using an iontophoretic device. (drugbank.ca)

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Reviews of research dating from the 1980s show there is some effect in reducing the number and duration of lesions if aciclovir is applied at an early stage of an outbreak. (wikipedia.org)
In both parts, the duration of virus shedding and the time to crusting and healing of lesions were shorter among acyclovir recipients than among placebo recipients. (nih.gov)

Your symptoms should improve during your treatment with acyclovir. (medlineplus.gov)
Treatment with acyclovir and hydrocortisone topical should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). (rexhealth.com)
Acyclovir and hydrocortisone topical may not be effective if taken after you already have symptoms. (pardeehospital.org)
Using acyclovir for cold sores has been proven most effective if it is applied early on as soon as the first symptoms of cold sores were felt (known as the Tingle stage). (coldsoreproof.com)
To the editor: After reading the report of Wade and Meyers (1) and the letter of Vartian and Shlaes (2) on neurologic deterioration after intravenous acyclovir treatment, we write to report that we have seen a remarkable improvement of the neurologic symptoms in a patient with Behçet's syndrome who was treated with acyclovir. (annals.org)

Acyclovir capsules are formulation for oral administration. (nih.gov)
A formulation for preparing Acyclovir Lip Balm. (ijpc.com)
A formulation for preparing Acyclovir 5% in Oral Adhesive Paste. (ijpc.com)
Acyclovir ointment USP 5% is a formulation for topical administration. (bioportfolio.com)
A formulation for preparing Acyclovir 5% and Chlorhexidine Diacetate 0.2% Topical Gel. (ijpc.com)

If you become pregnant while using acyclovir, call your doctor. (medlineplus.gov)
Likewise, oral and subcutaneous administration of acyclovir to pregnant mice, rats, and rabbits during organogenesis did not produce teratogenicity at clinically relevant doses [see Animal Data ]. (rxlist.com)
There are no acyclovir adequate and well-controlled studies of ointment systemic acyclovir in ointment pregnant women. (sportsrubbish.com)
The cases accumulated to date represent a sample of insufficient size for reaching reliable and definitive conclusions about the safety of acyclovir for pregnant women and their developing fetuses. (rti.org)

Acyclovir was not shown to be carcinogenic in mouse and rat bioassays at oral doses up to 450mg/kg (approximately 1100 - 2200 times the maximum RHOD, on a mg/m 2 basis, assuming 100% absorption). (rxlist.com)
In reproduction studies, acyclovir did not impair fertility or reproduction at oral doses up to 450 mg/kg/day in mice (1100 times the RHOD), or at subcutaneous doses of 25 mg/kg/day in rats (125 times the RHOD). (rxlist.com)
Very recently, utilization of higher doses of acyclovir for longer periods of time has been demonstrated to further improve the outcome of neonatal HSV disease. (aappublications.org)

Sarcoidosis is a adverse inflammatory granulomatous dis- ease that primarily binds the lungs, although multi-organ osteomalacia is aciclovir tratamiento para zoster. (cysers.info)

Each acyclovir capsule intended for oral administration contains 200 mg of acyclovir. (nih.gov)

The sodium salt form of acyclovir, a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. (cancer.gov)
Acyclovir, a synthetic acyclic nucleoside analog, is a substrate with a high degree of specificity for herpes simplex and varicella-zoster specified thymidine kinase. (rxmed.com)

Each gram of XERESE contains 50 mg (equivalent to 5%, w/w) acyclovir and 10 mg (equivalent to 1%, w/w) hydrocortisone in an aqueous cream base. (rxlist.com)

Only 1 graft rejection event was observed, 15 years after implantation, and was successfully treated with systemic acyclovir and topical corticosteroids. (aao.org)

A few reported cases of skin flushing, allergic inflammation, itching, stinging or burning sensations and skin drying has been associated with the use of Acyclovir. (coldsoreproof.com)

In general, the pharmacokinetics of acyclovir in children is similar to adults. (rxmed.com)

Do not apply other skin medications or other types of skin products such as cosmetics, sun screen, or lip balm to the cold sore area while using acyclovir cream unless your doctor tells you that you should. (medlineplus.gov)
Avoid irritation of the cold sore area while using acyclovir cream. (medlineplus.gov)

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Organisms4

Diseases15

Chemicals and Drugs17

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Phenomena and Processes2

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Information Science5

Health Care2

Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. (1/1121)

B cell lymphoproliferative disorders following hematopoietic stem cell transplantation: risk factors, treatment and outcome. (2/1121)

Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line. (3/1121)

Management of human cytomegalovirus infection and disease after allogeneic bone marrow transplantation. (4/1121)

Antiviral therapy for neonatal herpes simplex virus: a cost-effectiveness analysis. (5/1121)

Intravenous penciclovir for treatment of herpes simplex infections in immunocompromised patients: results of a multicenter, acyclovir-controlled trial. The Penciclovir Immunocompromised Study Group. (6/1121)

Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group. (7/1121)

Long term neurological outcome of herpes encephalitis. (8/1121)

Acyclovir

Antiviral Agents

Herpes Simplex

Herpes Genitalis

Herpes Zoster

Herpes Labialis

Herpesvirus 2, Human

Simplexvirus

Valine

Foscarnet

Ganciclovir

Encephalitis, Herpes Simplex

Ointments

Herpes Zoster Ophthalmicus

Prodrugs

Guanine

Stomatitis, Herpetic

Herpesvirus 3, Human

Keratitis, Dendritic

Thymidine Kinase

Herpesvirus 1, Human

Administration, Oral

Administration, Topical

Chickenpox

Virus Shedding

Viral Plaque Assay

Encephalitis, Varicella Zoster

Bell Palsy

Arabinofuranosyluracil

Skin Diseases, Viral

Phosphonoacetic Acid

Idoxuridine

Virus Activation

Pharmaceutical Vehicles

Inosine Pranobex

Double-Blind Method

Recurrence

Vidarabine

Keratitis, Herpetic

Electronic Mail

Food Dispensers, Automatic

Editorial Policies

Authorship

Periodicals as Topic

Postal Service

Internet

Solutions

Sodium

Universal Precautions

Injections

Facies

Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. (1/1121)

B cell lymphoproliferative disorders following hematopoietic stem cell transplantation: risk factors, treatment and outcome. (2/1121)

Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line. (3/1121)

Management of human cytomegalovirus infection and disease after allogeneic bone marrow transplantation. (4/1121)

Antiviral therapy for neonatal herpes simplex virus: a cost-effectiveness analysis. (5/1121)

Intravenous penciclovir for treatment of herpes simplex infections in immunocompromised patients: results of a multicenter, acyclovir-controlled trial. The Penciclovir Immunocompromised Study Group. (6/1121)

Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group. (7/1121)

Long term neurological outcome of herpes encephalitis. (8/1121)

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