Acute Radiation Syndrome

Radioactive Hazard Release

Radiation Injuries, Experimental

Radiation Injuries

Whole-Body Irradiation

Radiation-Protective Agents

Radiation Dosage

Lethal Dose 50

Dose-Response Relationship, Radiation

Radiodermatitis

Syndrome

Radiation Pneumonitis

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Medical Countermeasures

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trichology | Amy Ellis Nutt - Part 2

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17 million grant to fund seizure, neurotoxin research

Acute radiation syndrome

Sunburn

Treatment of infections after exposure to ionizing radiation

Sargramostim

Rongelap Atoll

List of civilian radiation accidents

Chronic radiation syndrome

Background radiation

Louis Slotin

Radiation-induced lung injury

Fukushima Daiichi nuclear disaster casualties

Romiplostim

Nuclear testing at Bikini Atoll

Volodymyr Pravyk

Chernobyl disaster

Maria Orbeli

Louis Hempelmann

Effective dose (radiation)

Radiation-induced cancer

Radiobiology

Nuclear warfare

Dose fractionation

May 1953

Aleksandr Akimov

Committed dose

Oishi Matashichi

Daigo Fukuryū Maru

Capture of Chernobyl

Poisoning of Alexander Litvinenko

Pegfilgrastim

Cushing's syndrome

List of cardiology mnemonics

Gastrointestinal disease

Nuclear power

Cardiac catheterization

Vagotomy

Appendicitis

Peripheral neuropathy

Pneumonitis

Slipped capital femoral epiphysis

Pheochromocytoma

Linear no-threshold model

Telomerase

Sex differences in human physiology

Cancer

Xerostomia

Neural tube defect

List of Ig Nobel Prize winners

Spinal cord injury

MECOM

Circadian rhythm

Skin temperature

Sensory neuron

Influenza

MicroRNA

Head injury

Chronic lymphocytic leukemia

Exposure to ionizing2

• Effect on intelligence test score of prenatal exposure to ionizing radiation in Hiroshima and Nagasaki: A comparison of the T65DR and DS86 dosimetry systems. (cdc.gov)
• Exposure to ionizing radiation can be a source of anxiety for many pregnant women and their health care providers. (cmaj.ca)

Lymphoblastic Leukemia3

• IMSEAR at SEARO: Secondary Malignancies Developing After Acute Lymphoblastic Leukemia And Its TreatmentWith Constitutional Mismatch Repair Deficiency Syndrome In Siblings. (who.int)
• Background & Objectives: Acute Lymphoblastic Leukemia (ALL) is the most common childhood malignancy, with an annual rate of 3 to 4 cases per 1,00,000 children. (who.int)
• Acute lymphoblastic leukemia (ALL) / lymphoblastic lymphoma (LBL), also known as acute lymphocytic leukemia / lymphoma or acute lymphoid leukemia, is a cancer of precursor B-cell, T-cell, or other cell types in which immature lymphoid cells accumulate in blood, bone marrow, or other tissue. (logicalimages.com)

Sickness14

• Acute Radiation Syndrome (ARS) , or radiation sickness, is a serious illness that can happen when a person is exposed to very high levels of radiation, usually over a short period of time. (cdc.gov)
• Alternatively, cases of radiation sickness have occurred as a result of patients unwittingly handling discarded radiation sources. (emra.org)
• The prodromal phase of acute radiation sickness occurs within minutes to days of exposure to at least 1 Gy. (emra.org)
• Acute radiation syndrome (ARS) which is also referred to as radiation sickness is a rare type of illness that causes certain damage to the body by a large dosage of penetrating radiation in a short span of time. (syndromespedia.com)
• What are the treatments for acute radiation sickness? (medlineplus.gov)
• The Department of Health and Human Services (HHS) says it has spent $290 million on a drug to treat radiation sickness in the event of a nuclear emergency. (wlns.com)
• The Food and Drug Administration first approved the drug in 2008 to combat an autoimmune disorder that caused serious bleeding and extended another approv al in January of last year for use of the drug as a radiation sickness treatment. (wlns.com)
• ARS, also known as radiation sickness, occurs when a person s entire body is exposed to a high dose of penetrating radiation, reaching internal organs in a matter of seconds. (informationliberation.com)
• Did seven busloads of Russian soldiers really get acute radiation sickness? (codastory.com)
• The US has stocked up on radiation sickness drugs just weeks after Vladimir Putin threatened to use nuclear weapons against the West. (endoftheamericandream.com)
• According to the announcement, Amgen's development of Nplate for radiation sickness was supported by the Biomedical Advanced Research and Development Authority (BARDA) and the National Institute of Allergy and Infectious Diseases (NIAID). (ntd.com)
• Russian forces may be withdrawing from Chernobyl, the Pentagon has said, as nuclear experts dismissed claims that occupying soldiers were suffering from acute radiation sickness. (plainsmenpost.com)
• However, nuclear experts have pointed out that the likelihood of soldiers suffering from acute radiation sickness caused by the site today was low. (plainsmenpost.com)
• He added: "There are other reasons Russian forces might visit the medical radiation facility besides actual sickness. (plainsmenpost.com)

Subsyndrome of Acute Radiati1

• Udenyca (pegfilgrastim-cbqv) is a prescription medicine used to treat the symptoms of Hematopoietic Subsyndrome of Acute Radiation Syndrome and prevention of chemotherapy -induced Neutropenia . (medicinenet.com)

Chronic7

• MRLs are derived for acute (1-14 days), intermediate (15-364 days), and chronic (365 days and longer) durations and for the oral, inhalation, and external routes of exposure. (cdc.gov)
• Toscano also mentions Aastrom Biosciences for chronic limbischemia, Aldagen for ischemic stroke, AlloCure Inc. for kidney injury, StemCells Inc. for spinal cord injuries and Osiris Therapeutics forgraft-versus-host disease (GvHD), Crohn's disease and acute radiation syndrome. (drugdiscoverynews.com)
• Radiation-induced gene expression (GE) changes observed within hours and days after irradiation have shown potential to serve as biomarkers for either dose reconstruction (retrospective dosimetry) or the prediction of consecutively occurring acute or chronic health effects. (uwo.ca)
• Likewise, endodontic procedures and therapies can cause an endo-antral syndrome 6-8 , the spread of pulpal disease beyond supporting tissues into the maxillary sinus causing acute or chronic sinusitis 1,5,8 . (bvsalud.org)
• Acute kidney injury (AKI) is a life-threatening disease with high mortality characterized by an abrupt decrease of the kidney glomerular filtration rate, extra-kidney consequences (cardiovascular diseases, lung injury, neurological impairment) and high risk of secondary chronic kidney disease (CKD). (hrb.ie)
• It can be acute (fast-growing) or chronic (slow growing). (kidshealth.org)
• Follow patients closely for evidence of transplant-related complications, including hyperacute graft-versus-host disease (GVHD), acute GVHD, chronic GVHD, hepatic veno-occlusive disease (VOD) after reduced intensity conditioning, and steroid-requiring febrile syndrome (without an identified infectious cause), and intervene promptly. (tecentriq-hcp.com)

Nuclear20

• Although more than 119 million U.S. residents live within 50 miles of a nuclear power plant, most emergency physicians are unfamiliar with management of radiation-related injuries, including mass casualty from nuclear accidents. (emra.org)
• Examples of individuals who had suffered from acute radiation syndrome are the ones who survived the atomic bombings of Hiroshima and Nagasaki during World War II, the firefighters who first made a response after the Chernobyl Nuclear Power Plant event back in 1986, and those who accidentally got exposed to sterilization irradiators. (syndromespedia.com)
• Acute radiation syndrome in Russian nuclear workers. (cdc.gov)
• However, workers at nuclear facilities, irradiation facilities, or nuclear waste storage sites may be exposed to radiation from these sources. (cdc.gov)
• Further, this work begins to establish a foundation for the successful development of new and improved ways to deal with serious exposure to radiation, whether the result of a laboratory accident, a nuclear energy plant disaster, or a terrorist act. (sri.com)
• Examples of job industries considered high risk for radiation exposure include medical fields, nuclear power plants, and the airline industry. (forthepeople.com)
• Ukraine's capital of Kyiv is rea dying evacuation centers with potassium iodine pills, which can help against radiation absorption, prepping for a potential nuclear attack on the city. (wlns.com)
• The Biden regime is buying up $290 million in anti-radiation drugs for use in "nuclear emergencies" amid escalating tensions with Russia and heightened threats of a nuclear war. (informationliberation.com)
• Acute radiation syndrome and its possible consequences are in the center of interest in recent times because of the possible threat to human kind from nuclear weapons. (com.hr)
• CBLB502, a polypeptide drug derived from Salmonella flagellin that binds to Toll-like receptor 5 (TLR5) and activates nuclear factor-κB signaling, protected mice from both gastrointestinal and hematopoietic acute radiation syndromes and resulted in improved survival. (semanticscholar.org)
• In the case of developing MCMs for radiological and nuclear threats, exposing human subjects to radiation is not be ethical or feasible. (humaneticscorp.com)
• It also holds promise as a drug for use by first responders and civilians who face the threat of radiation exposure from a nuclear accident or terrorist threat. (humaneticscorp.com)
• It has now been over 60 years since U.S. nuclear testing was conducted in the Pacific islands and Nevada, exposing military personnel to varying levels of ionizing radiation. (allenpress.com)
• One Medical Hazards Manage- ated with acute chemical or radio-nuclear thyroid cancer mortality of an additional ment Team (HazMaT) has been estab- events. (who.int)
• A radiation emergency can be caused by an overturned truck hauling radioactive material, a nuclear power plant accident, "dirty bomb," or a nuclear explosion. (cdc.gov)
• Jeremy Gordon, nuclear commentator at Fluent in Energy and member of the World Nuclear Association, said: The most intense radiation comes from nuclear material with a short half-life - decaying fast and giving off all its radiation in a hurry. (plainsmenpost.com)
• To my knowledge people who developed acute radiation syndrome from a nuclear accident have been the ones on the spot, even in the room, when it took place. (plainsmenpost.com)
• Professor Claire Corkhill, Chair in Nuclear Material Degradation at the University of Sheffield, tweeted: "I am an expert in this field, and I have consulted other biological radiation experts who have intimate knowledge of Chernobyl. (plainsmenpost.com)
• Following a radiation incident such as an improvised nuclear device (IND) detonation, state and local response authorities will need to establish one or more population monitoring and decontamination facilities to assess people for radioactive exposure, contamination, and the need for decontamination or other medical follow-up. (cdc.gov)
• Being exposed to radiation in the environment (such as nuclear radiation) or to the chemical benzene . (cancer.gov)

Symptoms19

• If you have these symptoms after a radiation emergency, seek medical attention as soon as emergency officials determine it is safe to do so. (cdc.gov)
• After the initial symptoms, a person usually looks and feels healthy for a period of time, after which he or she will become sick again with variable symptoms and severity that vary depending on the radiation dose that he or she received. (cdc.gov)
• Rapidly proliferating cell lines such as intestinal mucosa and bone marrow are most immediately sensitive to radiation and manifest the symptoms of Acute Radiation Syndrome. (emra.org)
• 3 Increasing doses of radiation leads to acceleration of the timeline such that exposure to higher levels of radiation can lead to immediate prodromal symptoms as well as progression to the manifest phase within hours to days. (emra.org)
• Time to onset of symptoms can help estimate the exposed dose of radiation. (emra.org)
• Generally, the greater the radiation exposure is, the more severe the symptoms will be. (syndromespedia.com)
• Manifest illness stage - The symptoms vary on the specific ARS syndrome and could last for hours or months. (syndromespedia.com)
• The treatments for acute radiation syndrome aim on the prevention of further contamination of the radiation, treat fatal injuries, reduce symptoms, and control pain. (syndromespedia.com)
• How soon they get sick again, which symptoms they have, and how sick they get depends on the amount of radiation they received. (medlineplus.gov)
• They will ask about your symptoms, do blood tests, and may use a device that measures radiation. (medlineplus.gov)
• One of the worst things about radiation exposure is that the symptoms do not show immediately. (forthepeople.com)
• Because the first symptoms of radiation exposure usually seem like common symptoms of ordinary diseases, some people downplay the need for medical checkups. (forthepeople.com)
• Acute Radiation Syndrome, caused by exposure to a high dose of radiation, can cause a range of symptoms . (wlns.com)
• A period without symptoms depends of the radiation dosis. (com.hr)
• An individual who receives an acute, whole body (DDE) radiation exposure of approximately 8 Gy will likely suffer symptoms of up to which level of the Acute Radiation Syndrome? (nrrpt.org)
• The timing of the onset of these symptoms is subacute rather than acute. (medscape.com)
• Acute onset of symptoms suggests vascular or electrical etiology such as bleeding or seizure. (medscape.com)
• Stevens Johnson Syndrome or SJS is a potentially deadly skin condition with symptoms similar to erythema multiforme but in a much more severe and extensive manner. (targetwoman.com)
• Stevens Johnson syndrome symptoms include flu-like symptoms in addition to the rashes. (targetwoman.com)

Levels of radiation4

• Exposure to low levels of radiation in the environment does not cause immediate health effects. (medlineplus.gov)
• Exposure to high levels of radiation over a short period of time causes people to become very ill or to die, within minutes to months. (centerforhealthsecurity.org)
• Everyone needs to be inside a shelter during the first hour following the detonation, when the levels of radiation are at their most dangerous. (centerforhealthsecurity.org)
• Going outside to get loved ones could expose you and them to dangerous levels of radiation. (cdc.gov)

Hematopoietic2

• There are no radioprotectors currently approved by the United States Food and Drug Administration (US FDA) for either the hematopoietic acute radiation syndrome (H-ARS) or for the acute radiation gastrointestinal syndrome (GI-ARS). (nih.gov)
• There are currently, however, three US FDA-approved medicinals that serve to mitigate acute irradiation-associated hematopoietic injury. (nih.gov)

Leukemia6

• Adult acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes a large number of abnormal blood cells. (cancer.gov)
• It is the most common type of acute leukemia in adults. (cancer.gov)
• AML is also called acute myelogenous leukemia and acute nonlymphocytic leukemia. (cancer.gov)
• Acute promyelocytic leukemia (APL) is a subtype of AML. (cancer.gov)
• Others are Lymphoma, Acute Myeloid Leukemia (AML) and Thyroid Cancer. (who.int)
• Among those affected, the majority develop cancer , most often acute myelogenous leukemia (AML), and 90% develop aplastic anemia (the inability to produce blood cells) by age 40. (wikipedia.org)

Injuries2

• Nplate is approved to treat blood cell injuries that accompany acute radiation syndrome in adult and pediatric patients (ARS). (informationliberation.com)
• Nplate is the trade name of romiplostim, which was approved by the U.S. Food and Drug Administration (FDA) in January 2021 to treat blood cell injuries that accompany acute radiation syndrome (ARS) in adults and children. (ntd.com)

CHERNOBYL2

• Two Chernobyl plant workers died due to the explosion on the night of the accident, and a further 28 people died within a few weeks as a result of acute radiation syndrome. (world-nuclear.org)
• After the accident at Chernobyl in 1986, residents were evacuated from a 1,000-square-mile exclusion zone around the plant where the radiation levels were highest. (plainsmenpost.com)

Gastrointestinal1

• The consequence could be acute radiation syndrome, including central nervous system, gastrointestinal and hematological syndrome. (com.hr)

Doses of radiation5

• This is because defective radiation equipment can expose the user to high doses of radiation. (forthepeople.com)
• As mentioned before, high doses of radiation come with serious effects. (forthepeople.com)
• Another health effect-having a higher chance of developing cancer later in life-comes from long-term exposure to low doses of radiation. (centerforhealthsecurity.org)
• Two workers died in the immediate aftermath, and high doses of radiation to 134 plant staff and emergency personnel resulted in acute radiation syndrome that rapidly proved fatal for 28 of them. (cancer.gov)
• But exposure to high doses of radiation during a radiation emergency can cause a range of harmful health effects . (cdc.gov)

Renal failure1

• Minor elevations in these molecules can be detected in the blood of patients without ACS in the setting of myocarditis (pericarditis), sepsis, renal failure, acute congestive heart failure (CHF), acute pulmonary embolism, or prolonged tachyarrhythmias. (medscape.com)

Failure syndromes1

• Although it is a very rare disorder, study of this and other bone marrow failure syndromes has improved scientific understanding of the mechanisms of normal bone marrow function and development of cancer. (wikipedia.org)

Dose of radiation3

• Cutaneous Radiation Injury (CRI) happens when exposure to a large dose of radiation causes injury to the skin. (cdc.gov)
• Acute radiation syndrome can occur when high-dose of radiation causes some damage or destroys a number of cells in the body. (syndromespedia.com)
• Most researchers agree that babies who receive a small dose of radiation (equal to 500 chest x-rays or less) at any time during pregnancy do not have an increased risk for birth defects. (flutrackers.com)

Myelodysplastic1

• Having a personal history of a blood disorder such as myelodysplastic syndrome . (cancer.gov)

Amount of radiation5

• The amount of radiation that a person's body absorbs is called the radiation dose. (cdc.gov)
• In general, to reduce total radiation exposure, the longer you can wait in safety, the lower the amount of radiation you will receive. (centerforhealthsecurity.org)
• The possibility of severe health effects depends on the gestational age of the fetus at the time of exposure and the amount of radiation it is exposed to. (flutrackers.com)
• However, the increased risks depend on the amount of radiation to which the baby was exposed and the amount of time that it was exposed. (flutrackers.com)
• This depends on the amount of radiation absorbed by the body (the dose), the type of radiation, and for how long the person was exposed. (cdc.gov)

Tumor2

• It is also being developed for the prevention of radiation-induced toxicities associated with solid tumor radiotherapy and is the subject of two active Investigational New Drug (IND) applications. (nih.gov)
• Tumor-induced glaucoma may be produced by obstruction of outflow pathways by pigment cells (pigment dispersion syndrome), melanin-laden macrophages (melanomalytic glaucoma), or tumor cells. (medscape.com)

Prevention2

• The Centers for Disease Control and Prevention (CDC) has prepared this fact sheet to help you understand the possible health effects to your fetus from exposure to radiation. (flutrackers.com)
• In addition, BIO 300 has been granted an Orphan Drug Designation for the Prevention of Acute Radiation Syndrome. (humaneticscorp.com)

Bone2

• The most prone areas of the body to high-dose radiation are those cells in the lining of the intestinal tract which involves the blood cell-producing cells of the bone marrow and the stomach. (syndromespedia.com)
• People exposed to radioactive material often die weeks later of acute radiation syndrome, as blood cells vital to clotting and fighting infection die off, and bone marrow cells killed by radiation cannot replace them. (newscientist.com)

NAUSEA1

• This radiation can cause immediate effects such as nausea, performance degradation and other acute radiation syndromes, while long-term effects can include cancer, degenerative tissue damage, heart disease and damage to the central nervous system. (agu.org)

Known as acute1

• This injury is known as acute radiation syndrome (ARS). (centerforhealthsecurity.org)

Injury7

• Radiation injury is caused by deposition of energy in tissues, which promotes free radicals and disruption of DNA and other cellular structures. (emra.org)
• The new data were to be used to test the triage scheme that had been developed by Thoma and Wald in 1959 to provide clinicians without any special knowledge about radiation effects with early diagnostic and prognostic information about the severity of such injury as a basis for medical management. (cdc.gov)
• We found that 22 of the 59 cases had more than one blood count within the first 72 hours after the radiation exposure, a prerequisite for the triage injury classification method to be tested. (cdc.gov)
• Garg S, Garg TK, Wise SY, Fatanmi OO, Miousse IR, Savenka AV, Basnakian AG, Singh VK, Hauer-Jensen M. Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate. (uams.edu)
• Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol. (uams.edu)
• Departments of neurooncology, acute injury of the central and peripheral nervous system, neuro-vascular pathology, restorative neurosurgery and pediatric neurosurgery were created. (kiev.ua)
• Later, research efforts focused on issues of diagnosis and surgical treatment of acute traumatic brain injury, neurooncology, treatment of pain syndromes, study of the pathogenesis of edema-swelling, acute prolapse of the brain. (kiev.ua)

Severe acute re5

• The outbreak of severe acute respiratory syndrome in 2002-2003 exacted considerable human and economic costs from countries involved. (cdc.gov)
• The causal agent of this disease was found to be a coronavirus, and the disease was named severe acute respiratory syndrome (SARS) ( 1 ). (cdc.gov)
• For this example we will use: Wuhan, China, severe acute respiratory syndrome. (visiblelegacy.com)
• Background: Current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are administered systemically and typically result in poor immunogenicity at the mucosa. (irta.cat)
• A 2003 outbreak of severe acute respiratory syndrome (SARS) infected more than 8,000 people and killed almost 800. (wordpress.com)

Chemotherapy5

• Smoking, previous chemotherapy treatment, and exposure to radiation may affect the risk of AML. (cancer.gov)
• Having had treatment with chemotherapy or radiation therapy in the past. (cancer.gov)
• Before undergoing an allogeneic stem cell transplant, you'll receive high doses of chemotherapy or radiation to destroy your diseased cells and prepare your body for the donor cells. (beaconhealthsystem.org)
• During the conditioning process, you'll receive high doses of chemotherapy or radiation therapy to kill your cancer cells. (beaconhealthsystem.org)
• Because cancer is a process and not a thing, attempting to surgically remove it, poison it with chemotherapy or burn it with radiation doesn't work. (cancercaremalaysia.com)

Diagnosis2

• A serial change in hsTnI or cTnI levels from admission (using the 99th percentile diagnostic cutoff value) to 3 hours postadmission may aid in early diagnosis of acute myocardial infarction. (medscape.com)
• The advantage of GE markers lies in their capability for early (1-3 days after irradiation), high-throughput, and point-of-care (POC) diagnosis required for the prediction of the acute radiation syndrome (ARS). (uwo.ca)

Effects26

• We present the current status of a promising radiation countermeasure, BIO 300 (a genistein-based agent), that has been extensively investigated in murine models of H-ARS and models of the delayed effects of acute radiation exposure (DEARE) and is currently being evaluated in large animal models. (nih.gov)
• Radiation effects resulting from ARS leads to a cellular degradation from the DNA damage and certain molecular structures in various tissues or cells of the body. (syndromespedia.com)
• The main objective of the parent project, Joint Collaborative Committee for Radiation Effects Research (JCCRER) Project 2.3, is the development of a database of Mayak PA workers to use for such purposes as the verification of current dose-effect models for deterministic effects of acute exposure including the acute radiation syndrome or ARS. (cdc.gov)
• The pilot research was carried out with DOE support (January 1997) to evaluate the possibility of applying primary clinical and dosimetry data available at FIB-l and Mayak P A to the study of deterministic effects from occupational radiation exposures. (cdc.gov)
• What are the health effects of radiation exposure? (medlineplus.gov)
• A fetus is most vulnerable to the effects of radiation. (medlineplus.gov)
• A disaster of such magnitude has brought new focus and urgency to studying the effects of radiation, protection, and therapy against radiation and radionuclides. (sri.com)
• On the other hand, radiation also has harmful effects, especially when introduced into the human body at high dosages. (forthepeople.com)
• These patients often question the potential effects of the radiation on the developing fetus, and they may perceive radiation as being very harmful. (cmaj.ca)
• Ionizing radiation can cause two types of effects. (cmaj.ca)
• With the atomic bombings in World War II, the world became aware of the serious potential carcinogenic, teratogenic and mutagenic effects of ionizing radiation. (cmaj.ca)
• Despite the increase in concern about the health effects of ionizing radiation, the medical use of x-rays has continued to grow. (cmaj.ca)
• Ionizing radiation has several biological effects on reproduction. (cmaj.ca)
• Unborn babies are especially sensitive to the cancer-causing effects of radiation. (flutrackers.com)
• Health effects other than cancer from radiation exposure are not likely when the dose to the fetus is very low. (flutrackers.com)
• Effects depend on radiation levels and length of exposure and may include skin burns, acute radiation syndrome, cardiovascular disease, and changes to genetic material, which may lead to cancer. (ccohs.ca)
• The United Nations Scientific Committee on the Effects of Atomic Radiation has concluded that, apart from some 5000 thyroid cancers (resulting in 15 fatalities), 'there is no evidence of a major public health impact attributable to radiation exposure 20 years after the accident. (world-nuclear.org)
• The paper deals with primary and secondary effects on the whole human body or its greater great part due to the ionizing radiation in a short time. (com.hr)
• The late effects of radiation develop slowly due to the long latency phase, until the development of malignant diseases. (com.hr)
• Humanetics is developing BIO 300 as a MCM to treat the effects of DEARE, focusing on radiation-induced pneumonitis and pulmonary fibrosis. (humaneticscorp.com)
• Some health effects of radiation may start right away or within several days, while others may not be apparent for many years. (cdc.gov)
• Effects from exposure to radiation can range from mild, such as skin reddening, to serious effects such as skin damage, acute radiation syndrome (ARS), and death. (cdc.gov)
• Since the Biological Effects of Ionizing Radiation VII review of the epidemiological data in 2006, many subsequent publications have reported excess cancer risks from low-dose exposures. (cdc.gov)
• Since the Biological Effects of Ionizing Radiation report by the National Academies in 2006, new publications from large, well-powered epidemiological studies of low doses have reported positive dose-response relationships. (cdc.gov)
• 2. Provision of accurate epidemiological data that can be integrated into long-term registries for follow up of latent health effects after radiation exposure. (cdc.gov)
• Biological effects of low-level radiation : proceedings of an International Symposium on the Effects of Low-Level Radiation with Special Regard to Stochastic and Non-Stochastic Effects, held in Venice, Italy, 11-15 April 1983 / jointly organized by the International Atomic Energy Agency and the World Health Organization. (who.int)

Myocardial infarction2

• Peak A is the early release of myoglobin or creatine kinase isoenzyme MB (CK-MB) after acute myocardial infarction (AMI). (medscape.com)
• Keller et al suggest that among patients with suspected acute coronary syndrome, highly sensitive troponin I assay (hsTnI) or contemporary troponin I assay (cTnI) determination 3 hours after admission for chest pain may facilitate early rule-out of acute myocardial infarction. (medscape.com)

Promising radiation countermeasure1

• Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: a promising radiation countermeasure. (uams.edu)

Occur5

• Radiation exposure can occur through inhalation, ingestion, and transdermal absorption. (emra.org)
• Radiation can occur naturally or be man-made. (medlineplus.gov)
• This can occur when the mother's abdomen is exposed to radiation from outside her body. (flutrackers.com)
• Therefore, the types of ious forms of radiation, carcinogen ifested as a higher incidence of the tumours that occur during childhood ic infectious agents, and chemicals same kinds of tumours that occur in in humans, including various embry and chemical mixtures. (who.int)
• Burns commonly occur by direct or indirect contact with heat, electric current, radiation, or chemical agents. (stlukes-stl.com)

Exposures4

• Common radiation exposures to low dosage of radiation like CT scans or X-rays do not cause ACS. (syndromespedia.com)
• BACKGROUND: Ionizing radiation is an established carcinogen, but risks from low-dose exposures are controversial. (cdc.gov)
• Furthermore, the magnitude of the cancer risks from these low-dose radiation exposures was statistically compatible with the radiation dose-related cancer risks of the atomic bomb survivors. (cdc.gov)
• Exposures like these, especially internally from ingestion and inhalation, would raise their statistical chance of developing cancer, but it would not deliver the huge whole-body-at-once dose you need for acute radiation syndrome. (plainsmenpost.com)

Oncology1

• Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. (medscape.com)

Electromagnetic7

• Reduce electromagnetic radiation exposure from your cell phone. (medlineplus.gov)
• For the purpose of this review, "radiation" refers to ionizing radiation (e.g., x-rays, γ-rays, radionuclides) and not to other forms of radiation (e.g., long-wavelength electromagnetic waves such as radar, microwaves, diathermy and FM radio waves). (cmaj.ca)
• Ionizing radiation in the form of x-rays and γ-rays are short-wavelength electromagnetic rays. (cmaj.ca)
• Radiation energy is energy related to ionizing, low-frequency electromagnetic, optical, or radio-frequency electromagnetic radiation. (ccohs.ca)
• Red light therapy is a term that encompasses both visible red and invisible near-infrared (NIR) wavelengths of electromagnetic radiation. (juvawave.com)
• It's important to understand the differences between various types of electromagnetic radiation so you can give your clients the best physical therapy results. (juvawave.com)
• The term "radiation" can be scary, but all light (and all heat) is a form of electromagnetic radiation. (juvawave.com)

Type of radiation3

• Internal contamination treatment - These may include potassium iodide, Prussian blue, and diethylenetriamine pentaacetic acid depending on the specific type of radiation. (syndromespedia.com)
• They also try get more information about the exposure, such as what type of radiation it was, how far away you were from the source of the radiation, and how long you were exposed. (medlineplus.gov)
• It is determined by multiplying the number of rads by the quality factor, a number reflecting the potential damage caused by the particular type of radiation. (cdc.gov)

Person's3

• The time for skin to heal depends on the radiation dose the person's skin received. (cdc.gov)
• Complete healing of the skin may take from several weeks up to a few years depending on the radiation dose the person's skin received. (cdc.gov)
• Radiation exposure before birth can increase a person's risk of getting cancer later in life. (flutrackers.com)

Pathogenesis1

• New areas of neurosurgery were developed: further study of the etiology and pathogenesis of acute cerebrovascular disturbance, diagnostics and surgical treatment of cerebral hemorrhagic strokes (G.P.Pedachenko, L.Ye.Pelekh, O.P.Burlutskyi), study of the pathogenesis and treatment of spinal cord compression, study of the dynamics epileptogenic foci and epilepsy surgery, stereotactic surgery for extrapyramidal hyperkinesia. (kiev.ua)

Ionizing Radiation8

• Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal tissue can also be damaged, leading to toxicity. (nature.com)
• Since invention of the x-ray in 1895, ionizing radiation has been harnessed for diagnostic and therapeutic purposes. (cmaj.ca)
• The outcome of damage to the organism by ionizing radiation is directly related to the time when the treatment began. (com.hr)
• We have recently completed a two-year BARDA contract for the continued development of BIO 300 as a pharmacological medical countermeasure (MCM) to ionizing radiation. (humaneticscorp.com)
• Enhanced Survival in Mice Exposed to Ionizing Radiation by Combination of Gamma-Tocotrienol and Simvastatin. (uams.edu)
• We therefore conclude that these new epidemiological studies directly support excess cancer risks from low-dose ionizing radiation. (cdc.gov)
• Whether low-dose ionizing radiation can cause cancer is a critical and long-debated question in radiation protection. (cdc.gov)
• The cause of ALL / LBL is unknown, but it has been associated with ionizing radiation as well as certain genetic abnormalities. (logicalimages.com)

Cancer8

• 60 Co (read as cobalt sixty) is used for sterilizing medical equipment and consumer products, radiation therapy for treating cancer patients, manufacturing plastics, and irradiating food. (cdc.gov)
• Exposure to high levels of cobalt radiation can cause changes in the genetic materials within cells and may result in the development of some types of cancer. (cdc.gov)
• Other sources are man-made, such as x-rays, radiation therapy to treat cancer, and electrical power lines. (medlineplus.gov)
• For example, radiation helps medical professionals conduct diagnostic tests and treat certain health problems such as cancer in the health sector. (forthepeople.com)
• It should be noted that although radiation can help treat cancer, it can also cause cancer if administered into the human body in high amounts. (forthepeople.com)
• Co-developed by Israeli startup StemRad and US aerospace company Lockheed Martin, the vest is personal protective equipment for astronauts beyond low Earth orbit (LEO) that noticeably reduces Radiation Exposure Induced Death (REID) such as cancer while eliminating the possibility of Acute Radiation Syndrome (ARS) due to solar particles (SPE. (nocamels.com)
• The aim of this monograph was to systematically review the potential biases in these studies (including dose uncertainty, confounding, and outcome misclassification) and to assess whether the subset of minimally biased studies provides evidence for cancer risks from low-dose radiation. (cdc.gov)
• The researchers hope to learn if combining the study drugs with surgery and radiation will get rid of the cancer from participants' prostates and reduce their prostate-specific antigen (PSA) to an undetectable level. (dana-farber.org)

Burns1

• Being exposed to a lot of radiation over a short period of time, such as from a radiation emergency , can cause skin burns . (medlineplus.gov)

Therapy7

• The general population is rarely exposed to radioactive cobalt unless a person is undergoing radiation therapy. (cdc.gov)
• Alternative causes of ST-segment and T-wave changes are left ventricular aneurysm, pericarditis, Prinzmetal angina, early repolarization, Wolff-Parkinson-White syndrome, and drug therapy (eg, with tricyclic antidepressants, phenothiazines). (medscape.com)
• Étant donné la rareté de nouvelles études et la faible qualité de plusieurs d'entre elles, l'AETMIS a appuyé en grande partie son évaluation sur des consensus d'experts, dont les deux principaux sont issus de l'Hyperbaric Oxygen Therapy Committee de l'Undersea and Hyperbaric Medical Society (UHMS) et de l'European Committee for Hyperbaric Medicine (ECHM). (bvsalud.org)
• Based on the results from the Phase 3 KEYNOTE-775/Study 309 trial, KEYTRUDA plus LENVIMA has been approved in the U.S. for patients with advanced endometrial carcinoma that is not microsatellite instability-high or dMMR, who have disease progression following prior systemic therapy in any setting and are not candidates for curative surgery or radiation. (merck.com)
• Davidson T, Zhang H, Dong H , Grams MP, Park SS, Yan Y. Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint Blockade. (mayo.edu)
• A patient with impaired immune system like HIV, or one who is undergoing radiation therapy has higher chances of SJS. (targetwoman.com)
• This three-week study evaluated the intensity of pre- and post-therapy pain in 52 patients with shoulder periarthritis (frozen shoulder), myofascial pain syndrome, or lateral epicondylitis. (juvawave.com)

Damage7

• People who receive a high radiation dose also can have skin damage. (cdc.gov)
• Caused by a critical exposure to radiation, acute radiation syndrome includes neutropenia, nervous system damage, and pneumonia with high fatality rate. (enzychem.com)
• Exposure to large amounts of radiation from radioactive cobalt can damage cells in your body from the radiation. (cdc.gov)
• But too much radiation can damage tissues by changing cell structure and damaging DNA. (medlineplus.gov)
• Fallout that has settled on the ground and building roofs can release this penetrating radiation, and it can then damage cells and tissues in the human body. (centerforhealthsecurity.org)
• 80 years) veteran controls were collected and evaluated for radiation-induced chromosome damage utilizing directional genomic hybridization (dGH), a cytogenomics-based methodology that facilitates simultaneous detection of translocations and inversions. (allenpress.com)
• REM relates the absorbed dose in human tissue to the effective biological damage of the radiation. (cdc.gov)

Diffuse1

• ECG can be diagnostic in acute pericarditis and typically shows diffuse ST elevation. (medscape.com)

Myalgias1

• For many children and young adolescents, intermittent viral syndromes with myalgias or athletic overuse are common problems that may have similar presentations to growing pains. (pediatriceducation.org)

Countermeasure1

• Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. (uams.edu)

Irradiation1

• Radiation-induced pneumonitis in humans usually becomes apparent approximately two to four months after irradiation exposure, while radiation-induced fibrosis develops six months or more after exposure. (humaneticscorp.com)

Illness1

• Stage 4 electrocardiograph changes in the same patient as in the previous image, taken approximately 3 months after acute pericardial illness. (medscape.com)

Lethal1

• We have found that BIO 300 given prophylactically dramatically increases survival in animal models exposed to an acute dose of lethal radiation. (humaneticscorp.com)

Pericarditis2

• Stage 1 electrocardiograph changes in a patient with acute pericarditis. (medscape.com)
• The ratio of the amplitude of ST segment to the amplitude of the T wave in leads I, V4, V5, and V6 on electrocardiogram can be used to differentiate acute pericarditis (AP) from early repolarization (ER) and early repolarization of left ventricular hypertrophy (ERLVH), according to a recent study. (medscape.com)

MeSH1

• Acute Radiation Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)