A condition caused by a brief whole body exposure to more than one sievert dose equivalent of radiation. Acute radiation syndrome is initially characterized by ANOREXIA; NAUSEA; VOMITING; but can progress to hematological, gastrointestinal, neurological, pulmonary, and other major organ dysfunction.
Uncontrolled release of radioactive material from its containment. This either threatens to, or does, cause exposure to a radioactive hazard. Such an incident may occur accidentally or deliberately.
Experimentally produced harmful effects of ionizing or non-ionizing RADIATION in CHORDATA animals.
Harmful effects of non-experimental exposure to ionizing or non-ionizing radiation in VERTEBRATES.
Irradiation of the whole body with ionizing or non-ionizing radiation. It is applicable to humans or animals but not to microorganisms.
Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other, e.g. military, purposes.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.
A cutaneous inflammatory reaction occurring as a result of exposure to ionizing radiation.
A characteristic symptom complex.
Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.

Expression of phospho-Elk-1 in rat gut after the whole body gamma irradiation. (1/35)

Gastrointestinal form is the second stage of acute radiation syndrome (ARS) with a threshold dose of 8 Gy in man. It represents an absolutely lethal clinical-pathological unit, necro-hemorrhagic enteritis and proctocolitis, with unknown causal therapy. Elk-1 is a protein acting as a transcription factor activating specified genes. The purpose of our study was to examine the expression of phospho-Elk-1 in irradiated jejunum and transversal colon of rats with radiation-induced enterocolitis and to assess the importance of this transcriptional factor as a biodosimetric marker of radiation-induced enteropathy. The laboratory rats were randomly divided into 21 groups, 10 animals per group, and irradiated with whole body gamma-irradiation of 1, 5, 10, 15, and 20 Gy. Samples of jejunum and transversal colon were taken 24, 48, 72, and 96 hours later, immunohisto-chemically stained, and the phospho-Elk-1 expression was examined using computer image analysis. A group of 10 sham-irradiated animals was used as control. Significantly increased expression of phospho-Elk-1 in rat jejunum has been found in all time intervals after irradiation by sublethal doses of 1 and 5 Gy, whereas after the irradiation by lethal doses, the expression of phospho-Elk-1 in rat jejunum varied considerably. Significantly increased expression of phospho-Elk-1 in transversal colon has also been found in the first days after irradiation by sublethal doses of 1 and 5 Gy. After irradiation by lethal doses, there was no uniform pattern of the changes in the expression of phospho-Elk-1 in rat transversal colon. The detection of phospho-Elk-1 might be considered as a suitable and very sensitive biodosimetric marker of radiation-induced injury of small and large intestine. According to our knowledge, this is the first study on the phospho-Elk-1 expression in irradiated jejunum and transversal colon in the rat.  (+info)

Transient impairment of hippocampus-dependent learning and memory in relatively low-dose of acute radiation syndrome is associated with inhibition of hippocampal neurogenesis. (2/35)

Neurogenesis in the adult hippocampus, which occurs constitutively, is vulnerable to ionizing radiation. In the relatively low-dose exposure of acute radiation syndrome (ARS), the change in the adult hippocampal function is poorly understood. This study analyzed the changes in apoptotic cell death and neurogenesis in the DGs of hippocampi from adult ICR mice with single whole-body gamma-irradiation using the TUNEL method and immunohistochemical markers of neurogenesis, Ki-67 and doublecortin (DCX). In addition, the hippocampus-dependent learning and memory tasks after single whole-body gamma-irradiation were examined in order to evaluate the hippocampus-related behavioral dysfunction in the relatively low-dose exposure of ARS. The number of TUNEL-positive apoptotic nuclei in the dentate gyrus (DG) was increased 6-12 h after acute gamma-irradiation (a single dose of 0.5 to 4 Gy). In contrast, the number of Ki-67- and DCX-positive cells began to decrease significantly 6 h postirradiation, reaching its lowest level 24 h after irradiation. The level of Ki-67 and DCX immunoreactivity decreased in a dose-dependent manner within the range of irradiation applied (0-4 Gy). In passive avoidance and object recognition memory test, the mice trained 1 day after acute irradiation (2 Gy) showed significant memory deficits, compared with the sham controls. In conclusion, the pattern of the hippocampus-dependent memory dysfunction is consistent with the change in neurogenesis after acute irradiation. It is suggested that a relatively low dose of ARS in adult ICR mice is sufficiently detrimental to interrupt the functioning of the hippocampus, including learning and memory, possibly through the inhibition of neurogenesis.  (+info)

Dose estimation by chromosome aberration analysis and micronucleus assays in victims accidentally exposed to (60)Co radiation. (3/35)


The radiation protection and therapy effects of mesenchymal stem cells in mice with acute radiation injury. (4/35)


Amifostine ameliorates recognition memory defect in acute radiation syndrome caused by relatively low-dose of gamma radiation. (5/35)

This study examined whether amifostine (WR-2721) could attenuate memory impairment and suppress hippocampal neurogenesis in adult mice with the relatively low-dose exposure of acute radiation syndrome (ARS). These were assessed using object recognition memory test, the terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling assay, and immunohistochemical markers of neurogenesis [Ki-67 and doublecortin (DCX)]. Amifostine treatment (214 mg/kg, i.p.) prior to irradiation significantly attenuated the recognition memory defect in ARS, and markedly blocked the apoptotic death and decrease of Ki-67- and DCX-positive cells in ARS. Therefore, amifostine may attenuate recognition memory defect in a relatively low-dose exposure of ARS in adult mice, possibly by inhibiting a detrimental effect of irradiation on hippocampal neurogenesis.  (+info)

Radiation rescue: mesenchymal stromal cells protect from lethal irradiation. (6/35)


Radiation injury after a nuclear detonation: medical consequences and the need for scarce resources allocation. (7/35)


Hematopoietic cell infusion for the treatment of nuclear disaster victims: new data from the Chernobyl accident. (8/35)


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Synonyms for Acute radiation syndrome in Free Thesaurus. Antonyms for Acute radiation syndrome. 7 synonyms for syndrome: condition, complaint, illness, symptoms, disorder, ailment, affliction. What are synonyms for Acute radiation syndrome?
This article concisely summarizes data on the action of one of the principal and best known growth factors, the granulocyte colony-stimulating factor (G-CSF), in a mammalian organism exposed to radiation doses inducing acute radiation syndrome. Highlighted are the topics of its real or anticipated use in radiation accident victims, the timing of its administration, the possibilities of combining G-CSF with other drugs, the ability of other agents to stimulate endogenous G-CSF production, as well as of the capability of this growth factor to ameliorate not only the bone marrow radiation syndrome but also the gastrointestinal radiation syndrome. G-CSF is one of the pivotal drugs in the treatment of radiation accident victims and its employment in this indication can be expected to remain or even grow in the future.
HAIFA, Israel, Dec. 07, 2017 (GLOBE NEWSWIRE) -- Pluristem Therapeutics Inc. (NASDAQ:PSTI) (TASE:PSTI), a leading developer of placenta-based cell therapy products, announced today the company will present data from its Phase II-equivalent study of PLX-R18 cells for the treatment of acute radiation syndrome (ARS) at the American Society of Hematologys (ASH) 59th Annual Meeting to be held in Atlanta, Georgia, on December 9-12, 2017.. The results of the study will be presented during Program Session 506: Hematopoiesis and Stem Cells: Microenvironment, Cell Adhesion, and Stromal Stem Cells. The poster, Intramuscular Administration of Placenta-Derived Stromal Cells Enhances Survival of Rhesus Macaque Monkeys Exposed to Total Body Irradiation, will describe data from a recently announced Phase II-equivalent study under the U.S. Food and Drug Administration (FDA) Animal Rule. The data demonstrate improved survival and hematological recovery of NHPs exposed to different levels of radiation. This ...
Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome) - Pipeline Review, H1 2017, provides an overview of the Radiation Toxicity (Radiation Sic
Acute effects of ionizing radiation were first observed when Wilhelm Röntgen intentionally subjected his fingers to X-rays in 1895. He published his observations concerning the burns that developed that eventually healed, and misattributed them to ozone. Röntgen believed the free radical produced in air by X-rays from the ozone was the cause, but other free radicals produced within the body are now understood to be more important. D. Walsh first established the symptoms of radiation sickness in 1897. Ingestion of radioactive materials caused many radiation-induced cancers in the 1930s, but no one was exposed to high enough doses at high enough rates to bring on acute radiation syndrome. The Radium Girls were female factory workers who contracted radiation poisoning from painting watch dials with self-luminous paint at the United States Radium factory in Orange, New Jersey, around 1917. The atomic bombings of Hiroshima and Nagasaki resulted in high acute doses of radiation to a large number of ...
After irradiation with 2, 4, 7, or 12 Gy, changes in the bone marrow cells over time were examined through H&E staining and Ki-67 staining, a proliferation marker. In minipigs irradiated with 2 or 4 Gy, the myeloid hematopoietic cells disappeared drastically, starting at 30 minutes after irradiation; at the 17-hour point, only a minimal number of myeloid cells remained. On day 3 after irradiation, only some plasmacytoid cells and erythroblasts were observed; Ki-67 positive cells were hardly found (Figure 4A and B). For minipigs irradiated with 7 or 12 Gy, bone marrow tissues were obtained when they succumbed. In the histological analysis, we found that the bone marrow of these 2 minipigs was replaced with adipose cells, with a very small number of plasmacytoid myeloid cells. Moreover, few Ki-67 positive cells were found in the bone marrow (Figure 4C ...
Some may think that certain data are emphasized in this and other chapters in an attempt to minimize the dangers of exposure to radiation. This is not at all true. I am trying to put the dangers in perspective and eliminate the Pavlovian negative response to even the very mention of the subject. Table 8 shows the accepted syndrome from short-term exposures. Please note that this table is in rems (not millirems) and can be mentally converted to centisieverts (cSvs) of the same numerical value. Radiation can obviously be very dangerous. But so can an unreasonable fear of radiation ...
Online conversion from Nausea And Vomiting (Acute Radiation Syndrome) to Hourly Average Background Radiation (Radiation Dose Examples). Radiation Converter.
Online conversion from Death (Acute Radiation Syndrome) to Dental Radiology (Radiation Dose Examples). Radiation Converter.
Online conversion from Death (Acute Radiation Syndrome) to Sievert (Sv, Dose Equivalent Radiation). Radiation Converter.
Online conversion from Nausea And Vomiting (Acute Radiation Syndrome) to Millirem (Dose Equivalent Radiation). Radiation Converter.
Sixteen Lewis (RT1l) rats were exposed to sublethal dose (7Gy) of Cs-137 TBI. Irradiated rats were divided into 4 experimental groups (n=4 each) based on therapeutic approach: Group 1 - no intervention; Group 2 - normal saline injection; Group 3 - allogeneic bone marrow transplantation (BMT) [ACI (RT1a)]; and Group 4 - DRCC transplantation [ACI/LEW (RT1a/RT1l]. Saline as well as cellular therapeutics were delivered into the femoral bone at 6 hours following TBI. DRCC were created by ex-vivo fusion of bone marrow cells derived from fully MHC mismatched LEW (RT1l) and ACI (RT1a) donors. Briefly, donor and recipient cells were isolated, separately stained with the PKH26 and PKH67 fluorescent dyes, fused with polyethylene glycol (PEG) and sorted by flow cytometry. Cells presenting double staining were transplanted in a dose 10-12 x 106. All animals received supportive treatment with prophylactic antibiotics, fluids, and softened food during 90-days follow-up. Blood samples were evaluated using ...
Disaster Med Public Health Prep. 2011 Oct;5(3):202-12. doi: 10.1001/dmp.2011.68. Epub 2011 Oct 10. Research Support, Non-U.S. Govt; Review
Exposure to high doses of ionizing radiation in the event of therapeutic, accidental or intentional incident such as nuclear/radiological warfare can lead to debilitating injuries to multiple organs resulting in death within days depending on the amount of radiation dose and the quality of radiation. Unfortunately, there is not a single FDA-licensed drug approved against acute radiation injury.. Radiation damage to multiple organs often described as multiple organ dysfunction syndrome (MODS) or acute radiation syndrome (ARS) results from rapid depletion of radiosensitive cells, these cells are usually the stem or progenitor cells with high proliferative capacity; naturally, bone marrow stem cells (BMSC), and intestinal stem cells (ISC), which are extremely critical in maintaining a pool of peripheral blood cells and in maintaining villi for the absorption of nutrients are highly sensitive to radiation. One of the most efficient ways of rescuing MODS is to administer fresh cells that can repair, ...
Date: August 22, 2013. Company: BCN Biosciences, headquartered in Pasadena, Calif.. Cooperative agreement amount: BARDA will contribute $4 million over two years About the cooperative agreement: Through this cooperative agreement, BARDA will fund and collaborate on proof-of-concept studies by BCN Biosciences to determine how well a novel small molecule called Yel002, created by the company, protects DNA from damage after the bodys cells are exposed to damaging levels of radiation. This approach may increase the likelihood that cells in the gastrointestinal injury will survive exposure to acute radiation.. The GI tract is particularly sensitive to radiation but currently there is no treatment or preventive measure for this type of ionizing (damaging) radiation injury.. Acute Radiation Syndrome, also known as ARS, is a serious illness that occurs when all or most of the body receives a high dose of radiation, such as after the detonation of a nuclear device. ARS involves injuries to the bodys ...
Acute radiation syndrome ( ARS ), also known as radiation poisoning , radiation sickness or radiation toxicity , is a collection of health effects which present within 24 hours of exposure to high...
Purpose: Discovery of agents that protect or mitigate normal tissue from radiation injury during radiotherapy, accidents, or terrorist attacks is of importance. Specifically, bone marrow insufficiency, with possible infection due to immunosuppression, can occur after total body irradiation (TBI) or regional irradiation and is a major component of the acute radiation syndrome. The purpose of this study was to identify novel radioprotectors and mitigators of the hematopoietic system.. Experimental Design: High-throughput screening of small-molecule libraries was done using viability of a murine lymphocyte line as a readout with further validation in human lymphoblastoid cells. The selected compounds were then tested for their ability to counter TBI lethality in mice.. Results: All of two major classes of antibiotics, tetracyclines and fluoroquinolones, which share a common planar ring moiety, were radioprotective. Furthermore, tetracycline protected murine hematopoietic stem/progenitor cell ...
Exposure to a moderate to high dose of ionizing radiation (IR) not only causes acute radiation syndrome but also induces long-term (LT) bone marrow (BM) injury. The latter effect of IR is primarily attributed to the induction of hematopoietic stem cell (HSC) senescence. Granulocyte colony-stimulating factor (G-CSF) is the only treatment recommended to be given to radiation victims soon after IR. However, clinical studies have shown that G-CSF used to treat the leukopenia induced by radiotherapy or chemotherapy in patients can cause sustained low white blood cell counts in peripheral blood. It has been suggested that this adverse effect is caused by HSC and hematopoietic progenitor cell (HPC) proliferation and differentiation stimulated by G-CSF, which impairs HSC self-renewal and may exhaust the BM capacity to exacerbate IR-induced LT-BM injury. C57BL/6 mice were exposed to 4 Gy γ-rays of total body irradiation (TBI) at a dose-rate of 1.08 Gy per minute, and the mice were treated with G-CSF (1 μg/each
Mass casualty scenarios of radiation exposure require high throughput biological dosimetry techniques for population triage, in order to rapidly identify individuals, who require clinical treatment. Accurate dose estimates can be made by biological dosimetry, to predict the acute radiation syndrome (ARS) within days after a radiation accident or a malicious act involving radiation. Timely information on dose is important for the medical management of acutely irradiated persons [1]. The aim of the study was to evaluate the usefulness of the micronuclei (MNi) scoring procedure in an experimental mode, where 500 binucleated cells were analyzed in different exposure dose ranges. Whole-body exposure was simulated in an in vitro experiment by irradiating whole blood collected from one healthy donor with 60 MeV protons and 250 keV X-rays, in the dose range of 0.3-4.0 Gy. For achieving meaningful results, sample scoring was performed by three independent persons, who followed guidelines described in ...
Cancer is a stochastic effect of radiation, meaning that the probability of occurrence increases with effective radiation dose, but the severity of the cancer is independent of dose. The speed at which cancer advances, the prognosis, the degree of pain, and every other feature of the disease are not functions of the radiation dose to which the person is exposed. This contrasts with the deterministic effects of acute radiation syndrome which increase in severity with dose above a threshold. Cancer starts with a single cell whose operation is disrupted. Normal cell operation is controlled by the chemical structure of DNA molecules, also called chromosomes. When radiation deposits enough energy in organic tissue to cause ionization, this tends to break molecular bonds, and thus alter the molecular structure of the irradiated molecules. Less energetic radiation, such as visible light, only causes excitation, not ionization, which is usually dissipated as heat with relatively little chemical damage. ...
SIGNS AND SYMPTOMS/ /ACUTE RADIATION SYNDROME/ Fifty persons involved in the cesium-137 accident in Goiania showed symptoms of whole-body and local acute irradiation and also external or internal contamination mainly due to ingestion or absorption of cesium-137. Fourteen of the 50 developed severe bone marrow depression characterized by neutropenia and thrombocytopenia. Eight of these 14 received GM-CSF intravenously. None were submitted to bone marrow transplantation. Four of the 14 died due to hemorrhage and infection. For those with significant internal contamination evaluated by in-vitro and in-vivo assays, Prussian Blue was administered with doses ranging from 1.5 to 10 g/day. Besides Prussian Blue, other measures were taken to increase decorporation of cesium-137, including administration of diuretics, water overload, and ergometric exercises. From 50 to 100 persons are being followed in a medical protocol ...
BackgroundIonizing radiation induces lipid peroxidation and forms reactive oxygen species (ROS) within the cell. Due to their highly reactive state, ROS have short diffusion distances and quickly transfer unbalanced electrons to neighboring molecules. This transfer cycle continues until it finally culminates in the generation of reactive alkenals such as 4-hydroxynonenal (4HNE). Under normal conditions, intracellular 4HNE levels are controlled by conjugation to glutathione and are actively transported from the cell; RLIP76 protein has been determined to be the major transport protein involved in the efflux of 4HNE-conjugates. Radiation induces significant oxidative stress, and the increased levels of 4HNE conjugates overwhelm transport capacity. When this occurs, further conjugation is inhibited and free 4HNE levels rise, triggering apoptosis. It was hypothesized that adding exogenous RLIP76 protein would reduce 4HNE levels and correspondingly increase the recovery from acute radiation syndrome (ARS) or
HAIFA, Israel, July 18, 2013-- Pluristem Therapeutics Inc., a leading developer of placenta-based cell therapies, announced today that the U.S. National Institute of Allergy and Infectious Diseases, part of the U.S. National Institutes of Health, has recommended to Pluristem that NIAID expand the scope of its ongoing animal research using PLX-RAD cells for the treatment of acute radiation syndrome.
Appropriate models are essential for making the transition from scientific discoveries to meaningful applications of the knowledge for human use. Acute as well as delayed effects of ionising radiation to the biological systems develop hierarchically starting from damage to the vital macromolecules up to the disturbances caused at the whole organism level. In vitro models like bacteria, yeast, various mammalian cells cultured as monolayers (2-D) and spheroids (3-D) as well as cells with specific genetic alterations have provided insight into the complex relationships between damage induction and various signal transduction pathways, allowing identification of molecular and sub-cellular targets vital to the fate of irradiated cells. On the other hand, in vivo models (multicellular whole organisms), ranging from simple worms to non-human primates, have been gainfully employed to evaluate efficacy as well as toxicity of potential countermeasure agents (molecules, combinations and formulated ...
The study assessed the safety and efficacy of Pluristem Therapeutics PLX-R18 following intramuscular injection into irradiated and non-irradiated NHPs.
Growing concern over terrorism and the possible use of weapons of mass destruction, including nuclear and radiologic devices, has drawn attention to the need to prepare for potential, large-scale radiation incidents.
Degenerative changes occur as soon as 30 minutes after exposure of 500-1000 rad. Initial effects are: impaired secretion of necessary fluids: cell breakdown results in failure of food and water absorption leading to infection and dehydration from diarrhea ...
Radiation doses exceeding a threshold of about 500 millisieverts (mSv) can cause tissue reactions in the human body, also called deterministic effects. They are the result of a massive cell killing and the subsequent loss of function of the affected organs or tissues. Particularly ...
Radiation doses exceeding a threshold of about 500 millisieverts (mSv) can cause tissue reactions in the human body, also called deterministic effects. They are the result of a massive cell killing and the subsequent loss of function of the affected organs or tissues.
Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia. By Oksana O. Shevchuk, Elisaveta A. Snezhkova, Anatoliy G. Bilous, Veronika V. Sarnatskaya, Kvitoslava I. Badakhivska, Larysa A. Sakhno, Vasyl F. Chekhun and Volodymyr G. Nikolaev. Leukopenia is an essential part of the clinical course of acute radiation sickness and is a side effect of anti-cancer treatment. In both situations, the main factors which determine the survival are the degree of bone marrow suppression and gastrointestinal tract damage due to the presence of a large pool of fast-dividing cells. Leuko- and neutropenia are main limiting factors which may contribute to chemotherapy failure. Hematopoietic cytokines the part of conventional therapy in this field, but their effects require boosting. That is why the use of means and methods of adsorption therapy is considered promising. Sorption therapy creates a basis for sorption detoxification, a doctrine of curative ...
NSWP is publishing the results of a global consultation exercise, carried out with our members in every region, and now written up into all the five languages of NSWP, for December 17th, International Day to End Violence Against Sex Workers.
The rationale for the use of the Animal Rule must be supported by proof-of-concept animal studies designed to ensure animal welfare, demonstrate relevance of the animal model (species susceptibility to the toxic agent and toxic response similar to humans), define the endpoint used to assess efficacy and predict human clinical benefit (eg, relief or prevention of adverse effects), ensure data quality and integrity in a contained environment, and be conducted under Good Laboratory Practice (GLP) guidelines. When efficacy is demonstrated in a single study, conducted in a sufficiently well‑characterized animal model, it may be necessary to repeat the study, preferably in another laboratory for confirmation. The investigational drug/biologic used in the adequate and well-controlled animal efficacy studies and in the animal pharmacokinetics and/or pharmacodynamics studies used to select a dose and dosing regimen in humans, ideally should be manufactured under current GMP regulations and be as close ...
Read Transcript, Download (.mov, 14MB). This final segment introduces the Clinical Decision Guide, a critical benchmark that can be used by clinicians in addition to other factors to help determine if medical countermeasures are indicated for a particular patient.. The Clinical Decision Guide (CDG) is an operational quantity that is specific to a type of radionuclide and a route of exposure (e.g. cesium-137 inhalational exposure). The CDG of children (0-18 yrs) and pregnant women is 20% that of adults.. For most radionuclides, the CDG is defined by the amount (activity) of radioactive material delivering an effective dose of 0.25 Sieverts (Sv) after incorporation into the body. This dose represents about a 1.3% lifetime risk of fatal cancer attributable to the exposure. Radiation measurements from a urine sample above a CDG value suggest the potential for a higher attributable lifetime fatal cancer risk and may help clinicians decide whether or not to start countermeasure treatment.. The CDG can ...
The National Institutes of Health recently posted a solicitation for the development of medical countermeasures to enhance platelet regeneration and survival following radiation exposure from a nuclear or radiological incident.
NAM and EATG, Europes community group for people with HIV, have launched a consensus statement, for endorsement by the HIV community, on using HIV treatment to prevent the transmission of HIV. ART drugs if taken as prescribed can effectively render people non-infectious. This treatment has not already ended the HIV epidemic for several reasons including lack of access to drugs, no global consensus on who should get them,.... ...
Circulation and muscle tone.. Many skin conditions are a result of a poor moisture barrier. An essential focus is to support restoration of the skin barrier. Working with advanced microcurrent/LED technology that is teamed with professional products and treatment, the skin is gently encouraged the skin to become healthier. There are newer paradigm shifts when it comes to skin correction. When the underlying skin structures remain strong and healthy, it manifests in the skins appearance. We believe that there is a place for all technology and newer chemical procedures. The global consensus from scientists, and many medical and skin care professionals is to protect the integrity of the skin during all procedures. Being too aggressive with treatments may actually age the skin faster. Your program is based on your age, skin condition and history. It also may require patience and time.. ...
The Addressing Lupus Pillars for Health Advancement (ALPHA) project is a unique global consensus initiative that seeks to identify and prioritize the fundamental barriers or knowledge gaps that will allow providers, researchers and scientists to improve diagnosis, treatment and systems of care for people with lupus.
Aim 2: Perform preliminary countermeasure evaluation using radioprotective/chemopreventive agents that target common pathways of radiation induced injury (e.g. inflammation).. ...
The premier source of breaking business news for the government contracting industry, GovCon Wire provides informative, to-the-point stories of the most significant contract awards, top-level executive moves, M&A activities and financial results of the sectors most notable players.. GovCon Wire is always on top of the most recent contracting sector activity and is updated in real time as the news breaks. ...
Sherman & Stephanie Stephanie is the Founder & CFO of Animals Rule Placement Foundation. It was her vision of no more homeless pets and Dont buy, Dont breed, Adopt that spearheaded her idea to form a non profit 501 (C) 3 Animal Rescue and make a difference in her community. Stephanie and her husband Carl…
Illnesses collectively called acute radiation syndrome occur within a few hours to months after exposure to high-dose radiation (from approximately 1-2 Gy to 10 Gy). The principal signs and symptoms include vomiting within a few hours, followed within days to weeks by diarrhea, reduced blood cell counts, bleeding, hair loss (epilation), and temporary male sterility. Diarrhea results from damage to cells lining the intestines, reduction in blood cells from death of hematopoietic stem cells in bone marrow, and bleeding from declining blood platelets generated from such stem cells. Hair is lost due to damage to hair-root cells. Hairs do not fall out but rather become thinner and eventually break off. Sterility occurs in men from damage to sperm-generating stem cells ...
HealthDay News) -- Once astronauts leave the Earths protective magnetic field, their cancer risk would soar while traveling to Mars, new research indicates.. Scientists said radiation exposure during a long-term deep-space mission would not only affect already damaged cells but also healthy ones nearby, doubling cancer risk.. Cosmic rays cause significant cell damage due from exposure to radiation, protons and heavy ions, the authors explained. Previous research has shown the health risks of deep space travel include cancer, cataracts, acute radiation syndromes, and problems with circulation and the central nervous system.. Typical risk models, including those used by NASA, assume radiation cancers are caused by DNA damage and mutations. These models, however, are based on much shorter times than a Mars mission would require, researchers noted.. Exploring Mars will require missions of 900 days or longer and includes more than one year in deep space where exposures to all energies of galactic ...
Soligenix, Inc., a Princeton, N.J.-based biopharmaceutical company, announced on Sunday that the U.S. Food and Drug Administration reviewed and approved its investigational new drug application for its gastrointestinal acute radiation syndrome drug.
Purpose: Studies of the association between ataxia telangiectasia-mutated (ATM) gene polymorphisms and acute radiation injuries are often small in sample size, and the results are inconsistent. We conducted the first meta-analysis to provide a systematic review of published findings. Methods and Materials: Publications were identified by searching PubMed up to April 25, 2014. Primary meta-analysis was performed for all acute radiation injuries, and subgroup meta-analyses were based on clinical endpoint. The influence of sample size and radiation injury incidence on genetic effects was estimated in sensitivity analyses. Power calculations were also conducted. Results: The meta-analysis was conducted on the ATM polymorphism rs1801516, including 5 studies with 1588 participants. For all studies, the cut-off for differentiating cases from controls was grade 2 acute radiation injuries. The primary meta-analysis showed a significant association with overall acute radiation injuries (allelic model: ...
The purpose of the present study was twofold: (1) to determine if X-irradiation can be considered a direct stress agent, and if so, to what extent it differs from other stressors; and (2) to further elucidate the role of the adrenal cortex in the radiation syndrome by determining the more immediate responses of this system to X-irradiation.
56 representatives of 34 global organisations have come together to reach consensus on the management of endometriosis, published in Human Reproduction.
While the concept of brain death is widely accepted, no universal criteria exist for its determination. This study compared guidelines from 80 countries finding that all standards specified exclusion of confounders, irreversible coma, absent motor response, and lack of brain-stem reflexes (see Wijdicks, The Diagnosis of Brain Death for more information). The majority of countries had medical practice standards (88%), legal standards (69%), utilized some form of apnea testing (59%), and required more than one physicians declaration (50%). Specifics varied widely on the qualifications of the physician, methods of apnea testing, and observation time before pronouncement of death. Regional differences were also noted, such as mandatory laboratory tests in Europe and Asia. Within the United States, brain death determination has been left to each state to decide (44 states and the District of Columbia have guidelines) whereas most African countries do not. Even if guidelines are not standardized, ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
The threat of bioterrorism, long ignored and denied, has heightened over the past few years. Recent events in Iraq, Japan, and Russia cast an ominous shadow. Two candidate agents are of special concern: smallpox and anthrax. The magnitude of the problems and the gravity of the scenarios associated with release of these organisms have been vividly portrayed by two epidemics of smallpox in Europe during the 1970s and by an accidental release of aerosolized anthrax from a Russian bioweapons facility in 1979. Efforts in the United States to deal with possible incidents involving bioweapons in the civilian sector have only recently begun and have made only limited progress. Only with substantial additional resources at the federal, state, and local levels can a credible and meaningful response be mounted. For longer-term solutions, the medical community must educate both the public and policy makers about bioterrorism and build a global consensus condemning its use.
We are pleased to announce that our side event safety for the multi-transfused patients has been confirmed to take place on Friday 26 May 2017 at the 70th World Health Assembly. Linked to WHA70 agenda item of Principles for global consensus on the donation and management of ...
There is growing global consensus that the Information and communication technologies (ICTs), and particularly Internet are providing a new framework and huge opportunities for economic, political and social development. The World Summit for Social Development (WSSD, Copenhagen, 1995) recognized that the new information technologies and new approaches to access to and use of technologies by people living in poverty can help in fulfilling social development goals; and therefore recognize the need to facilitate access to such technologies. WSSD emphasized that promoting access for all to education, information, technology and know-how is an essential means for enhancing communication and participation in civil, political, economic, social and cultural life, and for ensuring respect for civil, political, economic, social and cultural rights. The World Summit on the Information Society (WSIS), Geneva 2003 - Tunis 2005, the Copenhagen Declaration and Tunis Commitment all recognized that ICTs is a key to
1. Promote safeguarding Remote learning creates new health and safety risks for children.. Online engagement by minors can lead to different forms of abuse. Some children and young people unable to attend school will be at a greater risk of harm at home. Governments have a fundamental responsibility to mitigate these risks and promote the importance of different forms of safeguarding.. 2. Make teaching engagement with vulnerable and disadvantaged students the top priority. The evidence relating to distance learning identifies student motivation, engagement and self-regulation as the single biggest challenge facing the remote teacher. This challenge is exacerbated in several ways by disadvantage. Insights from this Evidence Review are consistent with the global consensus that policymakers must make learning continuity with disadvantaged and vulnerable students the top priority during the period of school closure. At a local level, teachers should use all available means to keep in touch with ...
The National Institute of Allergy and Infectious Diseases (NIAID), an institute within the NIH, is hoping to stave off the rise of the mutant zombies in th
The expanded Center for Innovation in Advanced Development and Manufacturing (CIADM) in Baltimore helps the Nations pandemic preparedness.
CLT-008 is developed by the U.S. Food and Drug Administration Animal Rule for ARS. This approval pathway is available when human efficacy studies are neither ethical nor feasible and requires […]. ...
TOWNSEND: Well, the FDA Advisory Committee meets next week in this public hearing. Chimerix will be at it. If Chimerix can get their drug together, they can compete for it. They will look at the animal rule and the testing thats been -- thats gone on. And by the way, we talk about $433 million contract. If you look at the contract, you will see there are a number of milestones that the Siga as a company and the drug, SD-246, must meet in order to get payments along the way. This is not a guaranteed -- $433 million contract ...
A new $17 million research center dedicated to identifying medical countermeasures for neurotoxic chemicals that cause seizures in humans has been established by the U.S. National Institutes of Health at the University of California, Davis.
... (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that ... "Time Phases of Acute Radiation Syndrome (ARS) - Dose >8 Gy". Radiation Emergency Medical Management. Archived from the original ... CDC Radiation Emergencies Acute Radiation Syndrome. 22 April 2019. Retrieved 17 May 2019. "Beir VII: Health Risks from Exposure ... Donnelly, EH; Nemhauser, JB; Smith, JM; Kazzi, ZN; Farfán, EB; Chang, AS; Naeem, SF (June 2010). "Acute radiation syndrome: ...
... it can initially hide a severe exposure to radioactivity resulting in acute radiation syndrome or other radiation-induced ... Symptoms common to heat illness and the prodromic stage of acute radiation syndrome like nausea, vomiting, fever, weakness/ ... "Acute Radiation Syndrome , CDC". 23 October 2020. "Sun protection". World Health Organization. Retrieved 28 March 2018. " ... Broad-spectrum sunscreens contain filters that protect against UVA radiation as well as UVB. Although UVA radiation does not ...
Chapter 2 Acute radiation syndrome Reeves GI. Medical implications of enhanced radiation weapons. Mil Med. 2010 ;175:964-70. ... In addition to infections due to neutropenia, a patient with the Acute Radiation Syndrome will also be at risk for viral, ... Bader JL, Nemhauser J, Chang F, Mashayekhi B, Sczcur M, Knebel A, Hrdina C, Coleman N.Radiation event medical management (REMM ... Exposure to higher doses of radiation is associated with systemic anaerobic infections due to gram negative bacilli and gram ...
In March 2018 the label was extended to use as a countermeasure for acute radiation syndrome. "US Sargramostim label" (PDF). ... FDA approves Leukine for Acute Radiation Syndrome. Retrieved 29 March 2018. (Drugs with non-standard legal status, Chemicals ... It is also used to treat neutropenia induced by chemotherapy during the treatment of acute myeloid leukemia. It also used as a ... Schmeck HM (1987-11-02). "Radiation Team Sent to Brazil Saves Two With a New Drug". New York Times. Retrieved 2012-06-20. " ...
They were suffering from acute radiation syndrome. 1955-1957: Internally displaced Rongelapese inhabitants repeatedly request ... on Radiation, Joint Comm". Congress, U. S. At. Energy, 86th Congress, 1st session, Washington, US GPO, 1959. {{cite journal}}: ... page 436.) 9.107 A radiation dose of 700 rads over a period of 96 hours would probably prove fatal in the great majority of ... US scientists note: "The habitation of these people on the island will afford most valuable ecological radiation data on human ...
Ten of the adults developed acute radiation syndrome. One exposed 60Co source was retrieved, but the source from the other ... Three weeks later, the worker suffered symptoms typical of acute radiation syndrome (vomiting, loss of hair, fatigue). One ... February 1, 2000 - Samut Prakan radiation accident: The radiation source of an expired teletherapy unit was purchased and ... Although the source of radiation was never conclusively determined, the US Nuclear Radiation Commission strongly suspected that ...
"Acute radiation syndrome and chronic radiation syndrome" (PDF). Hellenic Journal of Nuclear Medicine. 16 (1): 56-9. PMID ... Chronic radiation syndrome (CRS), or chronic radiation enteritis, is a constellation of health effects of radiation that occur ... unlike radiation-induced cancer. It is distinct from acute radiation syndrome, in that it occurs at dose rates low enough to ... Chronic radiation syndrome develops with a speed and severity proportional to the radiation dose received (i.e., it is a ...
There were 28 deaths from acute radiation syndrome. Total doses from the Fukushima I accidents were between 1 and 15 mSv for ... However, background radiation for occupational doses includes radiation that is not measured by radiation dose instruments in ... Background radiation description from the Radiation Effects Research Foundation Environmental and Background Radiation FAQ from ... Record radiation levels were found in a house where the effective dose due to ambient radiation fields was 131 mSv (13.1 rem) ...
Young also suffered from acute radiation syndrome, but recovered. By 28 January 1948 Graves, Kline and Perlman sought ... and they are not considered as relevant to acute radiation syndrome as absorbed doses. Recent documents have made various ... He quickly collapsed with acute radiation poisoning and died 25 days later in the Los Alamos base hospital. After World War II ... Graves, who was standing the closest to Slotin, also developed acute radiation sickness and was hospitalized for several weeks ...
Radiation Emergency Medical Management. "Time Phases of Acute Radiation Syndrome - Radiation Emergency Medical Management". www ... radiation fibrosis). Pulmonary radiation injury most commonly occurs as a result of radiation therapy administered to treat ... Radiation-induced lung injury (RILI) is a general term for damage to the lungs as a result of exposure to ionizing radiation. ... "Radiation-induced lung injury". Seminars in Radiation Oncology. 13 (3): 333-345. doi:10.1016/S1053-4296(03)00034-1. ISSN 1053- ...
Despite this, there were no deaths caused by acute radiation syndrome. Given the uncertain health effects of low-dose radiation ... No radiation-related deaths or acute diseases have been observed among the workers and general public exposed to radiation from ... among them that this figure was based on an assumption of acute deaths from low radiation doses. There is no known mechanism ... and about 4 people out of 10 can be expected to develop cancer without exposure to radiation. Further, the radiation exposure ...
... may be used to treat acute radiation syndrome. "To reduce radiation-induced bleeding, Nplate stimulates the body's ... Roberts, Lizzie (5 October 2022). "US splashes $290m on anti-radiation drugs after Putin ups nuclear threats". The Daily ...
Many of them soon began to show symptoms of acute radiation syndrome. They returned to the islands three years later but were ... that the crew members were infected with hepatitis C through blood transfusions during part of their acute radiation syndrome ... but they all soon became ill with the effects of acute radiation sickness. One fisherman died about six months later while ... An 11-year-old boy who was born on Bikini in 1971 died from cancer that was linked to radiation exposure that he received on ...
Experiencing early symptoms of Acute Radiation Syndrome (ARS), Pravyk and his men were forced to descend from the roof. ... Following the event, he was hospitalized with acute radiation syndrome and died sixteen days later. He was posthumously awarded ... Radiation damage to his bone marrow had lowered his white blood cell count, leaving him extremely vulnerable to infection, and ... After the initial symptoms of his radiation exposure passed, Pravyk was optimistic, and hoped that he would recover and see his ...
Of the hospitalized workers, 134 exhibited symptoms of acute radiation syndrome (including one disputed case). 28 of the ... combining the deaths of approximately 50 emergency workers who died soon after the accident from acute radiation syndrome, 15 ... of which 134 exhibited symptoms of acute radiation syndrome. Among those hospitalized, 28 died within the following three ... ISBN 978-0-87371-996-4. Reported thus far are 237 cases of acute radiation sickness and 31 deaths. Mould (2000), p. 29. "The ...
During her work, she got sick with acute radiation syndrome, which lead to her death. Maria Orbeli was buried at the ...
Hempelmann, Louis H.; Lisco, Hermann; Hoffman, Joseph G. (February 1, 1952). "The Acute Radiation Syndrome: A Study of Nine ... In 1967 a student at Jefferson Medical College who wanted to study the effects of radiation on the human body was referred to ... Plutonium is similar to radium in that it is deposited in the bones, where its alpha radiation may cause sarcoma, but while ... Hempelmann then embarked on a series of studies of children who had been given radiation therapy for thymus enlargement. At the ...
High doses can cause visually dramatic radiation burns, and/or rapid fatality through acute radiation syndrome. Controlled ... Ionizing radiation is generally harmful and potentially lethal to living things but can have health benefits in radiation ... but only the radiation type. Various body tissues react to ionising radiation in different ways, so the ICRP has assigned ... of low levels of ionizing radiation. It takes into account the type of radiation and the nature of each organ or tissue being ...
... whereas the same amount of acute external dose would invariably cause an earlier death by acute radiation syndrome. Internal ... In addition to conventional fatalities and acute radiation syndrome fatalities, nine children died of thyroid cancer, and it is ... This contrasts with the deterministic effects of acute radiation syndrome which increase in severity with dose above a ... This effect is responsible for acute radiation syndrome, but these heavily damaged cells cannot become cancerous. Lighter ...
Acute radiation syndrome, by acute whole-body radiation Radiation burns, from radiation to a particular body surface Radiation- ... High doses can cause visually dramatic radiation burns, and/or rapid fatality through acute radiation syndrome. Controlled ... but no cases of acute radiation syndrome- popularized the warnings of occupational health associated with radiation hazards. ... a potential side effect from radiation treatment against hyperthyroidism Chronic radiation syndrome, from long-term radiation. ...
Acute radiation syndrome is a result of irreversible bone marrow damage from high-energy radiation exposure. Due to the ... they provide almost no protection from externally penetrating gamma radiation, which is the cause of acute radiation syndrome ... attenuation to only the most radio-sensitive organs and tissues in efforts to defer the onset of acute radiation syndrome, the ... The detonation of a "dirty bomb" would not cause a nuclear explosion, nor would it release enough radiation to kill or injure a ...
"Acute Radiation Syndrome: A Fact Sheet for Physicians". Centers for Disease Control and Prevention. 4 April 2018. Retrieved 7 ... Experiments in radiation biology have found that as the absorbed dose of radiation increases, the number of cells which survive ... Hyperfractionated radiation therapy is given over the same period of time (days or weeks) as standard radiation therapy. ... Hyperfractionated radiation therapy is given over the same period of time (days or weeks) as standard radiation therapy. ...
... acute radiation syndrome) Tony Blair, Prime Minister of the United Kingdom; in Edinburgh Michelle Courchesne, Canadian ...
Akimov eventually succumbed to acute radiation syndrome two weeks after the disaster at the age of 33. His family was informed ... during which time they began to notice acute radiation syndrome on themselves and were sent to the infirmary. Akimov was ... the symptoms of radiation sickness had mostly worn away. His wife visited him in hospital and while aware he might not survive ... exposed during his work to a lethal dose of 15-20 Gy of radiation.[page needed] He was admitted to Pripyat Hospital but was ...
Intake of very large amounts of radioactive material can cause acute radiation syndrome (ARS) in rare instances. Examples ... In summary, not all radiation is harmful. The radiation can be absorbed through multiple pathways, varying due to the ... The radiation risk proposed by the International Commission on Radiological Protection (ICRP) predicts that an effective dose ... The most harmful way to absorb radiation is that of absorption because it is almost impossible to control how much will enter ...
Members of the crew suffered from acute radiation syndrome, with Kuboyama Aikichi dying of a related infection six months later ... When the tuna fishermen returned home, they exhibited symptoms of what would later be called acute radiation syndrome. Geiger ... Their catch of tuna and shark was also found to be contaminated with radiation, resulting in two tons of tuna buried at Tsukiji ... Oishi believed that his exposure to radiation caused this tragedy as well. In the mid-1990s, Oishi began to speak publicly at ...
The crew suffered acute radiation syndrome (ARS) for a number of weeks after the Bravo test in March. All recovered except for ... were diagnosed with acute radiation syndrome. The US did not respond to Nishiwaki's letter or to letters from other Japanese ... High levels of radiation were found in the men's hair and nails, and so the hospital was forced to cut off the rest of their ... Radiation sickness symptoms appeared later that day. Due to this, the fishermen called the white ash shi no hai (死の灰, death ash ...
This rumor led to further speculation in the press that the soldiers were suffering from acute radiation syndrome. One Russian ... "Ionizing Radiation Dose Ranges (Rem and Sievert charts)" (PDF). United States Department of Energy. June 2010. Archived (PDF) ... Gill, Victoria (25 February 2022). "Chernobyl: Radiation spike at nuclear plant seized by Russian forces". BBC News. Archived ... Nevertheless, the agency recognised that lack of electricity was likely to deteriorate radiation safety, specifically through ...
He died on 23 November, becoming the first confirmed victim of lethal polonium-210-induced acute radiation syndrome. ... Unlike most common radiation sources, polonium-210 emits very little gamma radiation (the low intensity gamma ray at an energy ... Both gamma rays and alpha particles are classified as ionizing radiation which can cause radiation damage. An alpha-emitting ... "Radiation on airliners may be from poisoned spy". CNN. 29 November 2006. Archived from the original on 29 November 2006. ...
... hematopoietic subsyndrome of acute radiation syndrome). Ristempa was approved for medical use in Australia in January 2017. ... and to increase survival in people acutely exposed to myelosuppressive doses of radiation ( ...
If caused by a tumor, it may be treated by a combination of surgery, chemotherapy, and/or radiation. If the pituitary was ... Abruptly stopping the medication can thus result in acute and potentially life-threatening adrenal insufficiency and the dose ... Cushing's syndrome was first described by American neurosurgeon Harvey Cushing in 1932. Cushing's syndrome may also occur in ... "Cushing syndrome". mayoclinic.org. Mayo Clinic. Retrieved June 5, 2022. "Cushing's Syndrome". National Endocrine and Metabolic ...
Infections Acute renal failure Cardiac infarction Rheumatic fever Injury Neoplasms Dressler's syndrome PericarditiS:p. 34 PR ... PAID: Pulmonic & Aortic Insufficiency=Diastolic.p. 32 CARDIAC RIND:p. 34 Collagen vascular disease Aortic aneurysm Radiation ... acute or chronic) Valve disease Aneurysm of Ventricles Dressler's Syndrome thromboEmbolism (mural thrombus) Recurrence/ mitral ... hyperthyroid Endocarditis Sick sinus syndrome ABCD:p. 30 Anti-coagulate Beta-block to control rate Cardiovert Digoxin 3 D's:p. ...
In the acute setting, this may be a cause of hepatic encephalopathy and hepatorenal syndrome. Other causes of chronic liver ... Inflammation of the rectum is known as proctitis, one cause of which is radiation damage associated with radiotherapy to other ... When symptoms occur, such as in acute pancreatitis, a person may experience acute-onset, severe mid-abdominal pain, nausea and ... Peutz-Jeghers syndrome can cause dark spots on the oral mucosa or on the lips or the skin around the mouth. Several GI diseases ...
... and some temporary serious injuries from acute radiation syndrome. The future predicted mortality from increases in cancer ... ISBN 978-1-55022-562-4. Johnston, Robert (2007-09-23). "Deadliest radiation accidents and other events causing radiation ... Low-level waste can be stored on-site until radiation levels are low enough to be disposed of as ordinary waste, or it can be ... The average dose from natural background radiation is 2.4 millisievert per year (mSv/a) globally. It varies between 1 mSv/a and ...
Acute coronary syndromes: ST elevation MI (STEMI), non-ST Elevation MI (NSTEMI), and unstable angina Evaluation of coronary ... Ideal table positioning between the x-ray source and receiver, and radiation monitoring via thermoluminescent dosimetry, are ... "Optimizing Radiation Safety in the Cardiac Catheterization Laboratory: A Practical Approach". Catheterization and ... internal and external Infection Radiation burn Contrast induced nephropathy from contrast use The likelihood of these risks ...
In humans, the VMH is sometimes injured by ongoing treatment for acute lymphoblastic leukemia or surgery or radiation to treat ... although adverse events have included gastric dumping syndrome (n=3), wound infection (n=2), other (n=5), and diarrhea (n=6). ... The preferred operation for perforations in acute duodenal ulcer". Annals of Surgery. 208 (2): 169-74. doi:10.1097/00000658- ... with adrenergic or serotonergic agents have previously met with little or only brief success in treating this syndrome." The ...
The presentation of acute appendicitis includes acute abdominal pain, nausea, vomiting, and fever. As the appendix becomes more ... Concerns about radiation tend to limit use of CT in pregnant women and children, especially with the increasingly widespread ... distal intestinal obstruction syndrome in children with cystic fibrosis; typhlitis in children with leukemia. Women: A ... Perman's sign: In acute appendicitis palpation in the left iliac fossa may produce pain in the right iliac fossa. While there ...
Carpal tunnel syndrome, electric shock, HIV, malignant disease, radiation, shingles, MGUS (Monoclonal gammopathy of ... Peripheral neuropathy may be acute (with sudden onset, rapid progress) or chronic (symptoms begin subtly and progress slowly), ... Guillain-Barré syndrome, systemic lupus erythematosus, leprosy, Sjögren's syndrome, Babesiosis, Lyme disease, vasculitis, ... Carpal tunnel syndrome and axillary nerve palsy are examples. Direct injury to a nerve, interruption of its blood supply ...
Hypersensitivity pneumonitis, also known as extrinsic allergic alveolitis (EAA) Acute Interstitial Pneumonitis Radiation ... bronchoalveolar allergic syndrome) Mercury exposure Smoking Overexposure to chlorine Bronchial obstruction (obstructive ... Radiation, used to treat cancer, can cause pneumonitis when applied to the chest or full body. Radiation pneumonitis occurs in ... oxford) Radiation Pneumonitis, also known as Radiation Induced Lung Injury, describes the initial damage done to the lung ...
... practically defined as when the patient is unable to ambulate even with crutches Temporal Acute Chronic Acute-on-chronic ... Over half of cases may have involvement on both sides (bilateral). Legg-Calvé-Perthes syndrome - another cause of avascular ... Other risk factors include: family history, endocrine disorders, radiation / chemotherapy, and mild trauma. The left hip is ... 17-47 percent of acute cases of SCFE lead to the death of bone tissue (osteonecrosis) effects. In general, SCFE is caused by ...
Radiation Therapy - With regard to pheochromocytoma, radiation techniques are primarily used for pain control, specifically ... Acute Renal Failure: Several reports have detailed rhabdomyolysis (rapid skeletal muscle breakdown) leading to acute kidney ... Multiple organ dysfunction syndrome (MODS): Caused by an elevated inflammatory response, multiple organ dysfunction is a severe ... Furthermore, if an acute adrenal hemorrhage is suspected in a pheochromocytoma patient, ultrasound is a quick, painless, ...
In contrast, deterministic health effects are radiation-induced effects such as acute radiation syndrome, which are caused by ... In very high dose radiation therapy, it was known at the time that radiation can cause a physiological increase in the rate of ... In a 2009 study, cancer rates among UK radiation workers were found to increase with higher recorded occupational radiation ... II: Sources and Effects of Ionizing Radiation: Annex G: Biological effects at low radiation doses. page 160, paragraph 541. ...
Treatment with both the siRNA and radiation caused a greater reduction in tumor size in mice than treatment with radiation ... Premature aging syndromes including Werner syndrome, Progeria, Ataxia telangiectasia, Ataxia-telangiectasia like disorder, ... "Dynamics of telomerase activity in response to acute psychological stress". Brain, Behavior, and Immunity. 24 (4): 531-9. doi: ... Bloom syndrome, Fanconi anemia and Nijmegen breakage syndrome are associated with short telomeres. However, the genes that have ...
Xg blood group Vitamin D resistant rickets Rett's syndrome Fragile X syndrome There are diseases that are caused by a defective ... Studies of rats show that males could learn better in the face of acute stress, while chronic stress is dealt with better by ... and in the temporal stem and optic radiation, of the left hemisphere, whereas females have a larger amount of gray matter in ... Pregnancy in the 40s or later has been correlated with increased risk of Down syndrome in children. Males are capable of ...
Medical use of ionizing radiation is a small but growing source of radiation-induced cancers. Ionizing radiation may be used to ... known as paraneoplastic syndromes. Common paraneoplastic syndromes include hypercalcemia, which can cause altered mental state ... In children, acute lymphoblastic leukemia and brain tumors are most common, except in Africa, where non-Hodgkin lymphoma occurs ... Radiation therapy involves the use of ionizing radiation in an attempt to either cure or improve symptoms. It works by damaging ...
"Patients with head and neck cancer cured by radiation therapy: a survey of the dry mouth syndrome in long-term survivors", Head ... There may be swollen salivary glands even without acute infection, possibly caused by autoimmune involvement. Dysgeusia - ... Primary Sjögren's syndrome is the combination of dry eyes and xerostomia. Secondary Sjögren's syndrome is identical to primary ... Sicca syndrome is not a specific condition, and there are varying definitions, but the term can describe oral and eye dryness ...
There are also several syndromes such as Meckel syndrome, and triploid syndrome which are frequently accompanied by neural tube ... environmental agents such as UV radiation. In concern with the latter, the UV radiation-induced folate photolysis has been ... Often, these defects are apparent at birth, but acute defects may not be diagnosed until much later in life. An elevated MSAFP ... Melanin works as either an optical filter to disperse the incoming UV radiation rays or free radical to stabilize the hazardous ...
Lewis, M. S.; Snyder, P. J.; Pietrzak, R. H.; Darby, D.; Feldman, R. A.; Maruff, P. (2011). "The effect of acute increase in ... "Argon plasma coagulation in the treatment of hemorrhagic radiation proctitis is efficient but requires a perfect colonic ... "Didgeridoo playing as alternative treatment for obstructive sleep apnoea syndrome: randomised controlled trial". BMJ. 332 (7536 ... ISBN 978-0-932081-19-3 Nolan, J. F.; Stillwell, T. J.; Sands Jr, J. P. (1990). "Acute management of the zipper-entrapped penis ...
Anterior spinal artery syndrome also known as anterior spinal cord syndrome, due to damage to the front portion of the spinal ... Acute SCI merits treatment in an intensive care unit, especially injuries to the cervical spinal cord. People with SCI need ... CT gives greater detail than X-rays, but exposes the patient to more radiation, and it still does not give images of the spinal ... Of the incomplete SCI syndromes, Brown-Séquard and central cord syndromes have the best prognosis for recovery and anterior ...
c-Jun N-terminal kinase (JNK) is a MAP kinase activated by extracellular stress signals such as gamma-radiation, ultraviolet ... One major cause of EVI1 activation and consequent overexpression is a clinical condition called 3q21q26 syndrome from inv(3)( ... Overexpression and aberrant expression of EVI1 has been associated with human acute myelogenous leukemia (AML), myelodysplastic ... it has been shown that development of acute myelogenous leukemia is likely due to several sequential genetic changes, and that ...
This form of familial advanced sleep phase syndrome is caused by a single amino acid change, S662➔G, in the human PER2 protein ... A reversal[clarification needed] in the sleep-wake cycle may be a sign or complication of uremia, azotemia or acute kidney ... with the purpose of protecting replicating DNA from high levels of damaging ultraviolet radiation during the daytime. As a ... Sinert T, Peacock PR (10 May 2006). "Renal Failure, Acute". eMedicine from WebMD. Retrieved 2008-08-03. Maung SC, El Sara A, ...
Heat loss from the skin to the external environment is a significant factor contributing to acute hypothermia. As the barrier ... Raynaud's phenomenon (also known as Raynaud's disease or syndrome) is an important condition affecting skin temperature of many ... which are the result of several factors including heat loss from subcutaneous tissues via radiation, conduction and ...
Electromagnetic radiation receptors respond to electromagnetic radiation Infrared receptors respond to infrared radiation ... Phantom limb syndrome is a sensory system disorder in which amputees perceive that their amputated limb still exists and they ... which target the sensory neural receptor to produce acute pain and subsequent pain hypersensitivity. Information coming from ... The mirror box developed by V.S. Ramachandran, has enabled patients with phantom limb syndrome to relieve the perception of ...
Other complications of infection include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre- ... less ultraviolet radiation from the Sun, and crowding. Influenza viruses that infect the upper respiratory tract like H1N1 tend ... acute respiratory distress syndrome (ARDS), sepsis, or if encephalitis, myocarditis, or breaking down of muscle tissue occur. ... and Guillain-Barré syndrome. Additionally, febrile seizures and Reye syndrome can occur, most commonly in children. Influenza- ...
Fasanaro P, Greco S, Ivan M, Capogrossi MC, Martelli F (January 2010). "microRNA: emerging therapeutic targets in acute ... or gamma radiation exposure. Viral microRNAs play an important role in the regulation of gene expression of viral and/or host ... structure of the hairpins in a pri-miRNA is recognized by a nuclear protein known as DiGeorge Syndrome Critical Region 8 (DGCR8 ... Kyriakidis I, Kyriakidis K, Tsezou A (August 2022). "MicroRNAs and the Diagnosis of Childhood Acute Lymphoblastic Leukemia: ...
Rao V, Syeda A, Roy D, Peters ME, Vaishnavi S (March 2017). "Neuropsychiatric aspects of concussion: acute and chronic sequelae ... In all cases, the patients develop post concussion syndrome, which includes memory problems, dizziness, tiredness, sickness and ... which unnecessarily exposes patients to radiation and increase time in the hospital and cost of the visit, multiple clinical ... "punch-drunk syndrome", caused by repetitive head injuries, for example in boxing or other contact sports A severe injury may ...
Shapira T, Pereg D, Lishner M (September 2008). "How I treat acute and chronic leukemia in pregnancy". Blood Reviews. 22 (5): ... There is no clear association between ionizing radiation exposure and the risk of developing CLL. Blood transfusions have been ... "France - Lymphoproliferative Syndrome B-Cell Prolymphocytic Leukemia ,". icgc.org. Retrieved 2016-11-18. "Hairy Cell Leukemia ... CLL should not be confused with acute lymphoblastic leukemia, a highly aggressive leukemia most commonly diagnosed in children ...
Information on acute radiation syndrome, its symptoms and treatment. Provided by the Centers for Disease Control and Prevention ... Acute Radiation Syndrome (ARS), or radiation sickness, is a serious illness that can happen when a person is exposed to very ... Radiation Dictionary. *Radiation Emergencies & Your Healthplus icon *Possible Health Effectsplus icon *Contamination and ... Cutaneous Radiation Injury (CRI) happens when exposure to a large dose of radiation causes injury to the skin. A doctor will ...
Information on acute radiation syndrome, its symptoms and treatment. Provided by the Centers for Disease Control and Prevention ... Acute Radiation Syndrome (ARS), or radiation sickness, is a serious illness that can happen when a person is exposed to very ... Radiation Dictionary. *Radiation Emergencies & Your Healthplus icon *Possible Health Effectsplus icon *Contamination and ... Cutaneous Radiation Injury (CRI) happens when exposure to a large dose of radiation causes injury to the skin. A doctor will ...
Acute radiation syndrome; BIO 300; biomarkers; delayed effects of acute radiation exposure; estrogen receptor; radiation ... for either the hematopoietic acute radiation syndrome (H-ARS) or for the acute radiation gastrointestinal syndrome (GI-ARS). ... radiation countermeasure under advanced development for acute radiation syndrome and the delayed effects of acute radiation ... that has been extensively investigated in murine models of H-ARS and models of the delayed effects of acute radiation exposure ...
A targeted look at the effects of radiation sickness and what measures to take for decontamination and initial treatment. ... Medical management of the acute radiation syndrome: recommendations of the Strategic National Stockpile Radiation Working Group ... So I Watched CHERNOBYL… Now What? Revisiting Acute Radiation Syndrome 10/10/2019 Leslie Crosby, MD , Laura Roper, MD , Dorian ... Medical management of the acute radiation syndrome. Rep Pract Oncol Radiother. 2011;16(4):138-146.. 6. Radiation Emergency ...
"Acute Radiation Syndrome" by people in this website by year, and whether "Acute Radiation Syndrome" was a major or minor topic ... "Acute Radiation Syndrome" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Acute radiation syndrome is initially characterized by ANOREXIA; NAUSEA; VOMITING; but can progress to hematological, ... Acute Radiation Syndrome*Acute Radiation Syndrome. *Acute Radiation Syndromes. *Radiation Syndrome, Acute ...
It is also referred to as radiation sickness is a rare type of illness ... Acute radiation syndrome can occur when high-dose of radiation causes some damage or destroys a number of cells in the body. ... Acute radiation syndrome (ARS) which is also referred to as radiation sickness is a rare type of illness that causes certain ... Radiation itself is the energy freed from atoms, either through a small particle of matter or a wave. Acute radiation syndrome ...
Caused by a critical exposure to radiation, acute radiation syndrome includes neutropenia, nervous system damage, and pneumonia ... ENZYCHEM LIFESCIENCES ANNOUNCES THE FDA ORPHAN DRUG DESIGNATION GRANTED TO EC-18 ON ACUTE RADIATION SYNDROME (ARS) The US FDA ...
Radiation-contamination; Dosimetry; Occupational-exposure; Workers; Workplace-studies; Acute-radiation-syndrome ... Acute Radiation Syndrome. The initial focus of effort on the NIOSH ARS project, a component of Project 2.3, waS to add clinical ... verification of current dose-effect models for deterministic effects of acute exposure including the acute radiation syndrome ... carry out the descriptive analysis of the pilot project database and to verify the existing models of acute radiation syndrome ...
... the radiation. You might also experience acute radiation syndrome that includes nausea, vomiting, diarrhea, bleeding, coma, and ... It takes about 5.27 years for half of 60Co to give off its radiation and about 272 days for 57Co; this is called the half-life. ... One is to see if you have been exposed to a large dose of radiation, and the other is to see if radioactive cobalt is in your ... Exposure to high levels of cobalt radiation can cause changes in the genetic materials within cells and may result in the ...
Acute pericarditis is an inflammation of the pericardium characterized by chest pain, pericardial friction rub, and serial ECG ... Common causes include acute myocardial infarction (MI), postinfarction (including Dressler syndrome), uremia, radiation, RA, ... Dressler syndrome. Dressler syndrome is now considered rare. When pericarditis associated with Dressler syndrome does occur, it ... Postpericardiotomy syndrome is similar to Dressler syndrome, except that postpericardiotomy syndrome occurs after cardiac ...
HN - 2008 BX - Immune Reconstitution Disease BX - Immune Restoration Syndrome MH - Acute Radiation Syndrome UI - D054508 MN - ... sievert dose equivalent of radiation. Acute radiation syndrome is initially characterized by ANOREXIA; NAUSEA; VOMITING; but ... HN - 2008 MH - Acute Coronary Syndrome UI - D054058 MN - C14.280.647.124 MN - C14.907.585.124 MS - An episode of MYOCARDIAL ... These abnormalities occur as a syndrome without other birth defects (cobblestone complex) or in other syndromes associated with ...
A lot over a short time, causes burns or radiation sickness. ... Radiation exposure to even small amounts over a long time, ... such as from a radiation emergency, can cause skin burns. It may also lead to acute radiation syndrome (ARS, or "radiation ... Acute Radiation Syndrome (Centers for Disease Control and Prevention) Also in Spanish ... What is radiation?. Radiation is energy. It travels in the form of energy waves or high-speed particles. Radiation can occur ...
Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal tissue can also be damaged, leading to ... Mice lacking RIP3 kinase are not protected from acute radiation syndrome. Radiat. Res. 189, 627-633 (2018). ... p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis. Science 327, 593-596 (2010). ... Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br. J. Dermatol. ...
Russian Soldiers Suffer Acute Radiation Syndrome At Chernobyl Ed Scarce - Mar 31st, 2022 ...
Public policy and disaster planning - acute radiation syndrome and radiation effects. In the event of Fukushima-type incident ... Radiation-induced damage, including mutagenesis and carcinogenesis. *Radiobiology and radiation exposure models in general, ... Biodosimetry methods to measure levels of radiation exposure and the effects of radiation both on earth and in space, including ... Radiation Drugs - A Hot Topic. Drug Development Research 73:229-231.. This project has been funded in part or in full by SRI ...
"Acute Radiation Syndrome (ARS) is a collection of health effects that present within 24 hours of exposure to high doses of ...
Morgan and Morgan radiation exposure lawyers can fight for you or your loved one who has been exposed to radiation. We have the ... Causes Acute Radiation Syndrome (ARS). *Cutaneous Radiation Injuries (CRI). *Increased risk of cancer ... Radiation Exposure Lawyer. There is no doubt that radiation plays a vital role in various aspects of our day-to-day lives. For ... Signs of Radiation Exposure in the Workplace One of the worst things about radiation exposure is that the symptoms do not show ...
Acute coronary syndrome (ACS) refers to a spectrum of clinical presentations ranging from those for ST-segment elevation ... This imaging modality exposes the patient to very little radiation (1-2 msV). No contrast is needed, and the study does not ... encoded search term (Acute Coronary Syndrome) and Acute Coronary Syndrome What to Read Next on Medscape ... for the Acute Coronary Syndrome Chapter Collaborators. Part 5: Acute coronary syndromes: 2015 international consensus on ...
... evaluating the effects of radiation exposure (NPHI, Tokyo, Japan); identifying and controlling measles outbreaks (Institut de ... The causal agent of this disease was found to be a coronavirus, and the disease was named severe acute respiratory syndrome ( ... Koplan JP, Butler-Jones D, Tsang T, Yu W. Public Health Lessons from Severe Acute Respiratory Syndrome a Decade Later. Emerg ... Public Health Lessons from Severe Acute Respiratory Syndrome a Decade Later. Emerging Infectious Diseases. 2013;19(6):861-863. ...
... vesicles derived from mesenchymal stromal cells mitigate intestinal toxicity in a mouse model of acute radiation syndrome. Stem ... also reported that MSC microvesicles, which are secreted membrane vesicles of 80 nm to 1 μm, improve acute kidney injury in a ... Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J. Am. Soc. Nephrol. 2009, 20, 1053-1067. [ ... Serum interleukin 17, interleukin 23, and interleukin 10 values in children with atopic eczema/dermatitis syndrome (AEDS): ...
290 million on a drug to treat radiation sickness in the event of a nuclear emergency. The HHS Administration for Strategic ... Acute Radiation Syndrome, caused by exposure to a high dose of radiation, can cause a range of symptoms. Severe cases can wreak ... The Department of Health and Human Services (HHS) says it has spent $290 million on a drug to treat radiation sickness in the ... Ukraines capital of Kyiv is readying evacuation centers with potassium iodine pills, which can help against radiation ...
This injury is known as acute radiation syndrome (ARS). After a nuclear explosion, people can avoid ARS by immediately finding ... How long do I need to stay in my shelter before its safe to come out? In general, to reduce total radiation exposure, the ... Potential radiation exposure decreases by 55% in the first hour following a detonation. If you move to a different shelter, ... Is it safe to eat and drink after a nuclear explosion, or will I get radiation inside me? You can avoid ingesting fallout by ...
290 million on a drug to treat radiation sickness in the event of a nuclear emergency. The HHS Administration for Strategic ... Acute Radiation Syndrome, caused by exposure to a high dose of radiation, can cause a range of symptoms. Severe cases can wreak ... The Department of Health and Human Services (HHS) says it has spent $290 million on a drug to treat radiation sickness in the ... Ukraines capital of Kyiv is readying evacuation centers with potassium iodine pills, which can help against radiation ...
... is a prescription medication used to prevent infection caused by chemotherapy and treat Hematopoietic Subsyndrome of Acute ... Radiation Syndrome. Serious side effects of Udenyca include hives, difficulty breathing, swelling, skin rash, sweating, ... is a prescription medicine used to treat the symptoms of Hematopoietic Subsyndrome of Acute Radiation Syndrome and prevention ... What Does Radiation Do to Your Body?. Radiation is a type of energy. Frequent exposure to even small amounts of radiation could ...
290 million in anti-radiation drugs for use in nuclear emergencies amid escalating tensions with Russia and heightened ... Repurposing drugs for acute radiation syndrome that also are approved for a commercial indication helps to sustain availability ... Nplate is approved to treat blood cell injuries that accompany acute radiation syndrome in adult and pediatric patients (ARS). ... ARS, also known as radiation sickness, occurs when a person s entire body is exposed to a high dose of penetrating radiation, ...
High levels of acute exposure to radiation (as low as 100 rad, usually above 400 rad) can cause acute radiation syndrome and ... Most radiodiagnostic examinations result in less than 5 rads radiation to the fetus.2,3,5,10 An estimate of radiation doses ... Radiation exposure dose is inversely related to the distance (to the power of two) from the radiation source. A lead shield may ... National Council on Radiation Protection and Measurements (NCRP). Ionizing radiation exposure of the population of the United ...
  • Effect on intelligence test score of prenatal exposure to ionizing radiation in Hiroshima and Nagasaki: A comparison of the T65DR and DS86 dosimetry systems. (cdc.gov)
  • Exposure to ionizing radiation can be a source of anxiety for many pregnant women and their health care providers. (cmaj.ca)
  • IMSEAR at SEARO: Secondary Malignancies Developing After Acute Lymphoblastic Leukemia And Its TreatmentWith Constitutional Mismatch Repair Deficiency Syndrome In Siblings. (who.int)
  • Background & Objectives: Acute Lymphoblastic Leukemia (ALL) is the most common childhood malignancy, with an annual rate of 3 to 4 cases per 1,00,000 children. (who.int)
  • Acute lymphoblastic leukemia (ALL) / lymphoblastic lymphoma (LBL), also known as acute lymphocytic leukemia / lymphoma or acute lymphoid leukemia, is a cancer of precursor B-cell, T-cell, or other cell types in which immature lymphoid cells accumulate in blood, bone marrow, or other tissue. (logicalimages.com)
  • Acute Radiation Syndrome (ARS) , or radiation sickness, is a serious illness that can happen when a person is exposed to very high levels of radiation, usually over a short period of time. (cdc.gov)
  • Alternatively, cases of radiation sickness have occurred as a result of patients unwittingly handling discarded radiation sources. (emra.org)
  • The prodromal phase of acute radiation sickness occurs within minutes to days of exposure to at least 1 Gy. (emra.org)
  • Acute radiation syndrome (ARS) which is also referred to as radiation sickness is a rare type of illness that causes certain damage to the body by a large dosage of penetrating radiation in a short span of time. (syndromespedia.com)
  • What are the treatments for acute radiation sickness? (medlineplus.gov)
  • The Department of Health and Human Services (HHS) says it has spent $290 million on a drug to treat radiation sickness in the event of a nuclear emergency. (wlns.com)
  • The Food and Drug Administration first approved the drug in 2008 to combat an autoimmune disorder that caused serious bleeding and extended another approv al in January of last year for use of the drug as a radiation sickness treatment. (wlns.com)
  • ARS, also known as radiation sickness, occurs when a person s entire body is exposed to a high dose of penetrating radiation, reaching internal organs in a matter of seconds. (informationliberation.com)
  • Did seven busloads of Russian soldiers really get acute radiation sickness? (codastory.com)
  • The US has stocked up on radiation sickness drugs just weeks after Vladimir Putin threatened to use nuclear weapons against the West. (endoftheamericandream.com)
  • According to the announcement, Amgen's development of Nplate for radiation sickness was supported by the Biomedical Advanced Research and Development Authority (BARDA) and the National Institute of Allergy and Infectious Diseases (NIAID). (ntd.com)
  • Russian forces may be withdrawing from Chernobyl, the Pentagon has said, as nuclear experts dismissed claims that occupying soldiers were suffering from acute radiation sickness. (plainsmenpost.com)
  • However, nuclear experts have pointed out that the likelihood of soldiers suffering from acute radiation sickness caused by the site today was low. (plainsmenpost.com)
  • He added: "There are other reasons Russian forces might visit the medical radiation facility besides actual sickness. (plainsmenpost.com)
  • Udenyca (pegfilgrastim-cbqv) is a prescription medicine used to treat the symptoms of Hematopoietic Subsyndrome of Acute Radiation Syndrome and prevention of chemotherapy -induced Neutropenia . (medicinenet.com)
  • MRLs are derived for acute (1-14 days), intermediate (15-364 days), and chronic (365 days and longer) durations and for the oral, inhalation, and external routes of exposure. (cdc.gov)
  • Toscano also mentions Aastrom Biosciences for chronic limbischemia, Aldagen for ischemic stroke, AlloCure Inc. for kidney injury, StemCells Inc. for spinal cord injuries and Osiris Therapeutics forgraft-versus-host disease (GvHD), Crohn's disease and acute radiation syndrome. (drugdiscoverynews.com)
  • Radiation-induced gene expression (GE) changes observed within hours and days after irradiation have shown potential to serve as biomarkers for either dose reconstruction (retrospective dosimetry) or the prediction of consecutively occurring acute or chronic health effects. (uwo.ca)
  • Likewise, endodontic procedures and therapies can cause an endo-antral syndrome 6-8 , the spread of pulpal disease beyond supporting tissues into the maxillary sinus causing acute or chronic sinusitis 1,5,8 . (bvsalud.org)
  • Acute kidney injury (AKI) is a life-threatening disease with high mortality characterized by an abrupt decrease of the kidney glomerular filtration rate, extra-kidney consequences (cardiovascular diseases, lung injury, neurological impairment) and high risk of secondary chronic kidney disease (CKD). (hrb.ie)
  • It can be acute (fast-growing) or chronic (slow growing). (kidshealth.org)
  • Follow patients closely for evidence of transplant-related complications, including hyperacute graft-versus-host disease (GVHD), acute GVHD, chronic GVHD, hepatic veno-occlusive disease (VOD) after reduced intensity conditioning, and steroid-requiring febrile syndrome (without an identified infectious cause), and intervene promptly. (tecentriq-hcp.com)
  • Although more than 119 million U.S. residents live within 50 miles of a nuclear power plant, most emergency physicians are unfamiliar with management of radiation-related injuries, including mass casualty from nuclear accidents. (emra.org)
  • Examples of individuals who had suffered from acute radiation syndrome are the ones who survived the atomic bombings of Hiroshima and Nagasaki during World War II, the firefighters who first made a response after the Chernobyl Nuclear Power Plant event back in 1986, and those who accidentally got exposed to sterilization irradiators. (syndromespedia.com)
  • Acute radiation syndrome in Russian nuclear workers. (cdc.gov)
  • However, workers at nuclear facilities, irradiation facilities, or nuclear waste storage sites may be exposed to radiation from these sources. (cdc.gov)
  • Further, this work begins to establish a foundation for the successful development of new and improved ways to deal with serious exposure to radiation, whether the result of a laboratory accident, a nuclear energy plant disaster, or a terrorist act. (sri.com)
  • Examples of job industries considered high risk for radiation exposure include medical fields, nuclear power plants, and the airline industry. (forthepeople.com)
  • Ukraine's capital of Kyiv is rea dying evacuation centers with potassium iodine pills, which can help against radiation absorption, prepping for a potential nuclear attack on the city. (wlns.com)
  • The Biden regime is buying up $290 million in anti-radiation drugs for use in "nuclear emergencies" amid escalating tensions with Russia and heightened threats of a nuclear war. (informationliberation.com)
  • Acute radiation syndrome and its possible consequences are in the center of interest in recent times because of the possible threat to human kind from nuclear weapons. (com.hr)
  • CBLB502, a polypeptide drug derived from Salmonella flagellin that binds to Toll-like receptor 5 (TLR5) and activates nuclear factor-κB signaling, protected mice from both gastrointestinal and hematopoietic acute radiation syndromes and resulted in improved survival. (semanticscholar.org)
  • In the case of developing MCMs for radiological and nuclear threats, exposing human subjects to radiation is not be ethical or feasible. (humaneticscorp.com)
  • It also holds promise as a drug for use by first responders and civilians who face the threat of radiation exposure from a nuclear accident or terrorist threat. (humaneticscorp.com)
  • It has now been over 60 years since U.S. nuclear testing was conducted in the Pacific islands and Nevada, exposing military personnel to varying levels of ionizing radiation. (allenpress.com)
  • One Medical Hazards Manage- ated with acute chemical or radio-nuclear thyroid cancer mortality of an additional ment Team (HazMaT) has been estab- events. (who.int)
  • A radiation emergency can be caused by an overturned truck hauling radioactive material, a nuclear power plant accident, "dirty bomb," or a nuclear explosion. (cdc.gov)
  • Jeremy Gordon, nuclear commentator at Fluent in Energy and member of the World Nuclear Association, said: The most intense radiation comes from nuclear material with a short half-life - decaying fast and giving off all its radiation in a hurry. (plainsmenpost.com)
  • To my knowledge people who developed acute radiation syndrome from a nuclear accident have been the ones on the spot, even in the room, when it took place. (plainsmenpost.com)
  • Professor Claire Corkhill, Chair in Nuclear Material Degradation at the University of Sheffield, tweeted: "I am an expert in this field, and I have consulted other biological radiation experts who have intimate knowledge of Chernobyl. (plainsmenpost.com)
  • Following a radiation incident such as an improvised nuclear device (IND) detonation, state and local response authorities will need to establish one or more population monitoring and decontamination facilities to assess people for radioactive exposure, contamination, and the need for decontamination or other medical follow-up. (cdc.gov)
  • Being exposed to radiation in the environment (such as nuclear radiation) or to the chemical benzene . (cancer.gov)
  • If you have these symptoms after a radiation emergency, seek medical attention as soon as emergency officials determine it is safe to do so. (cdc.gov)
  • After the initial symptoms, a person usually looks and feels healthy for a period of time, after which he or she will become sick again with variable symptoms and severity that vary depending on the radiation dose that he or she received. (cdc.gov)
  • Rapidly proliferating cell lines such as intestinal mucosa and bone marrow are most immediately sensitive to radiation and manifest the symptoms of Acute Radiation Syndrome. (emra.org)
  • 3 Increasing doses of radiation leads to acceleration of the timeline such that exposure to higher levels of radiation can lead to immediate prodromal symptoms as well as progression to the manifest phase within hours to days. (emra.org)
  • Time to onset of symptoms can help estimate the exposed dose of radiation. (emra.org)
  • Generally, the greater the radiation exposure is, the more severe the symptoms will be. (syndromespedia.com)
  • Manifest illness stage - The symptoms vary on the specific ARS syndrome and could last for hours or months. (syndromespedia.com)
  • The treatments for acute radiation syndrome aim on the prevention of further contamination of the radiation, treat fatal injuries, reduce symptoms, and control pain. (syndromespedia.com)
  • How soon they get sick again, which symptoms they have, and how sick they get depends on the amount of radiation they received. (medlineplus.gov)
  • They will ask about your symptoms, do blood tests, and may use a device that measures radiation. (medlineplus.gov)
  • One of the worst things about radiation exposure is that the symptoms do not show immediately. (forthepeople.com)
  • Because the first symptoms of radiation exposure usually seem like common symptoms of ordinary diseases, some people downplay the need for medical checkups. (forthepeople.com)
  • Acute Radiation Syndrome, caused by exposure to a high dose of radiation, can cause a range of symptoms . (wlns.com)
  • A period without symptoms depends of the radiation dosis. (com.hr)
  • An individual who receives an acute, whole body (DDE) radiation exposure of approximately 8 Gy will likely suffer symptoms of up to which level of the Acute Radiation Syndrome? (nrrpt.org)
  • The timing of the onset of these symptoms is subacute rather than acute. (medscape.com)
  • Acute onset of symptoms suggests vascular or electrical etiology such as bleeding or seizure. (medscape.com)
  • Stevens Johnson Syndrome or SJS is a potentially deadly skin condition with symptoms similar to erythema multiforme but in a much more severe and extensive manner. (targetwoman.com)
  • Stevens Johnson syndrome symptoms include flu-like symptoms in addition to the rashes. (targetwoman.com)
  • Exposure to low levels of radiation in the environment does not cause immediate health effects. (medlineplus.gov)
  • Exposure to high levels of radiation over a short period of time causes people to become very ill or to die, within minutes to months. (centerforhealthsecurity.org)
  • Everyone needs to be inside a shelter during the first hour following the detonation, when the levels of radiation are at their most dangerous. (centerforhealthsecurity.org)
  • Going outside to get loved ones could expose you and them to dangerous levels of radiation. (cdc.gov)
  • There are no radioprotectors currently approved by the United States Food and Drug Administration (US FDA) for either the hematopoietic acute radiation syndrome (H-ARS) or for the acute radiation gastrointestinal syndrome (GI-ARS). (nih.gov)
  • There are currently, however, three US FDA-approved medicinals that serve to mitigate acute irradiation-associated hematopoietic injury. (nih.gov)
  • Adult acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes a large number of abnormal blood cells. (cancer.gov)
  • It is the most common type of acute leukemia in adults. (cancer.gov)
  • AML is also called acute myelogenous leukemia and acute nonlymphocytic leukemia. (cancer.gov)
  • Acute promyelocytic leukemia (APL) is a subtype of AML. (cancer.gov)
  • Others are Lymphoma, Acute Myeloid Leukemia (AML) and Thyroid Cancer. (who.int)
  • Among those affected, the majority develop cancer , most often acute myelogenous leukemia (AML), and 90% develop aplastic anemia (the inability to produce blood cells) by age 40. (wikipedia.org)
  • Nplate is approved to treat blood cell injuries that accompany acute radiation syndrome in adult and pediatric patients (ARS). (informationliberation.com)
  • Nplate is the trade name of romiplostim, which was approved by the U.S. Food and Drug Administration (FDA) in January 2021 to treat blood cell injuries that accompany acute radiation syndrome (ARS) in adults and children. (ntd.com)
  • Two Chernobyl plant workers died due to the explosion on the night of the accident, and a further 28 people died within a few weeks as a result of acute radiation syndrome. (world-nuclear.org)
  • After the accident at Chernobyl in 1986, residents were evacuated from a 1,000-square-mile exclusion zone around the plant where the radiation levels were highest. (plainsmenpost.com)
  • The consequence could be acute radiation syndrome, including central nervous system, gastrointestinal and hematological syndrome. (com.hr)
  • This is because defective radiation equipment can expose the user to high doses of radiation. (forthepeople.com)
  • As mentioned before, high doses of radiation come with serious effects. (forthepeople.com)
  • Another health effect-having a higher chance of developing cancer later in life-comes from long-term exposure to low doses of radiation. (centerforhealthsecurity.org)
  • Two workers died in the immediate aftermath, and high doses of radiation to 134 plant staff and emergency personnel resulted in acute radiation syndrome that rapidly proved fatal for 28 of them. (cancer.gov)
  • But exposure to high doses of radiation during a radiation emergency can cause a range of harmful health effects . (cdc.gov)
  • Minor elevations in these molecules can be detected in the blood of patients without ACS in the setting of myocarditis (pericarditis), sepsis, renal failure, acute congestive heart failure (CHF), acute pulmonary embolism, or prolonged tachyarrhythmias. (medscape.com)
  • Although it is a very rare disorder, study of this and other bone marrow failure syndromes has improved scientific understanding of the mechanisms of normal bone marrow function and development of cancer. (wikipedia.org)
  • Cutaneous Radiation Injury (CRI) happens when exposure to a large dose of radiation causes injury to the skin. (cdc.gov)
  • Acute radiation syndrome can occur when high-dose of radiation causes some damage or destroys a number of cells in the body. (syndromespedia.com)
  • Most researchers agree that babies who receive a small dose of radiation (equal to 500 chest x-rays or less) at any time during pregnancy do not have an increased risk for birth defects. (flutrackers.com)
  • Having a personal history of a blood disorder such as myelodysplastic syndrome . (cancer.gov)
  • The amount of radiation that a person's body absorbs is called the radiation dose. (cdc.gov)
  • In general, to reduce total radiation exposure, the longer you can wait in safety, the lower the amount of radiation you will receive. (centerforhealthsecurity.org)
  • The possibility of severe health effects depends on the gestational age of the fetus at the time of exposure and the amount of radiation it is exposed to. (flutrackers.com)
  • However, the increased risks depend on the amount of radiation to which the baby was exposed and the amount of time that it was exposed. (flutrackers.com)
  • This depends on the amount of radiation absorbed by the body (the dose), the type of radiation, and for how long the person was exposed. (cdc.gov)
  • It is also being developed for the prevention of radiation-induced toxicities associated with solid tumor radiotherapy and is the subject of two active Investigational New Drug (IND) applications. (nih.gov)
  • Tumor-induced glaucoma may be produced by obstruction of outflow pathways by pigment cells (pigment dispersion syndrome), melanin-laden macrophages (melanomalytic glaucoma), or tumor cells. (medscape.com)
  • The Centers for Disease Control and Prevention (CDC) has prepared this fact sheet to help you understand the possible health effects to your fetus from exposure to radiation. (flutrackers.com)
  • In addition, BIO 300 has been granted an Orphan Drug Designation for the Prevention of Acute Radiation Syndrome. (humaneticscorp.com)
  • The most prone areas of the body to high-dose radiation are those cells in the lining of the intestinal tract which involves the blood cell-producing cells of the bone marrow and the stomach. (syndromespedia.com)
  • People exposed to radioactive material often die weeks later of acute radiation syndrome, as blood cells vital to clotting and fighting infection die off, and bone marrow cells killed by radiation cannot replace them. (newscientist.com)
  • This radiation can cause immediate effects such as nausea, performance degradation and other acute radiation syndromes, while long-term effects can include cancer, degenerative tissue damage, heart disease and damage to the central nervous system. (agu.org)
  • Radiation injury is caused by deposition of energy in tissues, which promotes free radicals and disruption of DNA and other cellular structures. (emra.org)
  • The new data were to be used to test the triage scheme that had been developed by Thoma and Wald in 1959 to provide clinicians without any special knowledge about radiation effects with early diagnostic and prognostic information about the severity of such injury as a basis for medical management. (cdc.gov)
  • We found that 22 of the 59 cases had more than one blood count within the first 72 hours after the radiation exposure, a prerequisite for the triage injury classification method to be tested. (cdc.gov)
  • Garg S, Garg TK, Wise SY, Fatanmi OO, Miousse IR, Savenka AV, Basnakian AG, Singh VK, Hauer-Jensen M. Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate. (uams.edu)
  • Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol. (uams.edu)
  • Departments of neurooncology, acute injury of the central and peripheral nervous system, neuro-vascular pathology, restorative neurosurgery and pediatric neurosurgery were created. (kiev.ua)
  • Later, research efforts focused on issues of diagnosis and surgical treatment of acute traumatic brain injury, neurooncology, treatment of pain syndromes, study of the pathogenesis of edema-swelling, acute prolapse of the brain. (kiev.ua)
  • The outbreak of severe acute respiratory syndrome in 2002-2003 exacted considerable human and economic costs from countries involved. (cdc.gov)
  • The causal agent of this disease was found to be a coronavirus, and the disease was named severe acute respiratory syndrome (SARS) ( 1 ). (cdc.gov)
  • For this example we will use: Wuhan, China, severe acute respiratory syndrome. (visiblelegacy.com)
  • Background: Current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are administered systemically and typically result in poor immunogenicity at the mucosa. (irta.cat)
  • A 2003 outbreak of severe acute respiratory syndrome (SARS) infected more than 8,000 people and killed almost 800. (wordpress.com)
  • Smoking, previous chemotherapy treatment, and exposure to radiation may affect the risk of AML. (cancer.gov)
  • Having had treatment with chemotherapy or radiation therapy in the past. (cancer.gov)
  • Before undergoing an allogeneic stem cell transplant, you'll receive high doses of chemotherapy or radiation to destroy your diseased cells and prepare your body for the donor cells. (beaconhealthsystem.org)
  • During the conditioning process, you'll receive high doses of chemotherapy or radiation therapy to kill your cancer cells. (beaconhealthsystem.org)
  • Because cancer is a process and not a thing, attempting to surgically remove it, poison it with chemotherapy or burn it with radiation doesn't work. (cancercaremalaysia.com)
  • A serial change in hsTnI or cTnI levels from admission (using the 99th percentile diagnostic cutoff value) to 3 hours postadmission may aid in early diagnosis of acute myocardial infarction. (medscape.com)
  • The advantage of GE markers lies in their capability for early (1-3 days after irradiation), high-throughput, and point-of-care (POC) diagnosis required for the prediction of the acute radiation syndrome (ARS). (uwo.ca)
  • We present the current status of a promising radiation countermeasure, BIO 300 (a genistein-based agent), that has been extensively investigated in murine models of H-ARS and models of the delayed effects of acute radiation exposure (DEARE) and is currently being evaluated in large animal models. (nih.gov)
  • Radiation effects resulting from ARS leads to a cellular degradation from the DNA damage and certain molecular structures in various tissues or cells of the body. (syndromespedia.com)
  • The main objective of the parent project, Joint Collaborative Committee for Radiation Effects Research (JCCRER) Project 2.3, is the development of a database of Mayak PA workers to use for such purposes as the verification of current dose-effect models for deterministic effects of acute exposure including the acute radiation syndrome or ARS. (cdc.gov)
  • The pilot research was carried out with DOE support (January 1997) to evaluate the possibility of applying primary clinical and dosimetry data available at FIB-l and Mayak P A to the study of deterministic effects from occupational radiation exposures. (cdc.gov)
  • What are the health effects of radiation exposure? (medlineplus.gov)
  • A fetus is most vulnerable to the effects of radiation. (medlineplus.gov)
  • A disaster of such magnitude has brought new focus and urgency to studying the effects of radiation, protection, and therapy against radiation and radionuclides. (sri.com)
  • On the other hand, radiation also has harmful effects, especially when introduced into the human body at high dosages. (forthepeople.com)
  • These patients often question the potential effects of the radiation on the developing fetus, and they may perceive radiation as being very harmful. (cmaj.ca)
  • Ionizing radiation can cause two types of effects. (cmaj.ca)
  • With the atomic bombings in World War II, the world became aware of the serious potential carcinogenic, teratogenic and mutagenic effects of ionizing radiation. (cmaj.ca)
  • Despite the increase in concern about the health effects of ionizing radiation, the medical use of x-rays has continued to grow. (cmaj.ca)
  • Ionizing radiation has several biological effects on reproduction. (cmaj.ca)
  • Unborn babies are especially sensitive to the cancer-causing effects of radiation. (flutrackers.com)
  • Health effects other than cancer from radiation exposure are not likely when the dose to the fetus is very low. (flutrackers.com)
  • Effects depend on radiation levels and length of exposure and may include skin burns, acute radiation syndrome, cardiovascular disease, and changes to genetic material, which may lead to cancer. (ccohs.ca)
  • The United Nations Scientific Committee on the Effects of Atomic Radiation has concluded that, apart from some 5000 thyroid cancers (resulting in 15 fatalities), 'there is no evidence of a major public health impact attributable to radiation exposure 20 years after the accident. (world-nuclear.org)
  • The paper deals with primary and secondary effects on the whole human body or its greater great part due to the ionizing radiation in a short time. (com.hr)
  • The late effects of radiation develop slowly due to the long latency phase, until the development of malignant diseases. (com.hr)
  • Humanetics is developing BIO 300 as a MCM to treat the effects of DEARE, focusing on radiation-induced pneumonitis and pulmonary fibrosis. (humaneticscorp.com)
  • Some health effects of radiation may start right away or within several days, while others may not be apparent for many years. (cdc.gov)
  • Effects from exposure to radiation can range from mild, such as skin reddening, to serious effects such as skin damage, acute radiation syndrome (ARS), and death. (cdc.gov)
  • Since the Biological Effects of Ionizing Radiation VII review of the epidemiological data in 2006, many subsequent publications have reported excess cancer risks from low-dose exposures. (cdc.gov)
  • Since the Biological Effects of Ionizing Radiation report by the National Academies in 2006, new publications from large, well-powered epidemiological studies of low doses have reported positive dose-response relationships. (cdc.gov)
  • 2. Provision of accurate epidemiological data that can be integrated into long-term registries for follow up of latent health effects after radiation exposure. (cdc.gov)
  • Biological effects of low-level radiation : proceedings of an International Symposium on the Effects of Low-Level Radiation with Special Regard to Stochastic and Non-Stochastic Effects, held in Venice, Italy, 11-15 April 1983 / jointly organized by the International Atomic Energy Agency and the World Health Organization. (who.int)
  • Peak A is the early release of myoglobin or creatine kinase isoenzyme MB (CK-MB) after acute myocardial infarction (AMI). (medscape.com)
  • Keller et al suggest that among patients with suspected acute coronary syndrome, highly sensitive troponin I assay (hsTnI) or contemporary troponin I assay (cTnI) determination 3 hours after admission for chest pain may facilitate early rule-out of acute myocardial infarction. (medscape.com)
  • Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: a promising radiation countermeasure. (uams.edu)
  • Radiation exposure can occur through inhalation, ingestion, and transdermal absorption. (emra.org)
  • Radiation can occur naturally or be man-made. (medlineplus.gov)
  • This can occur when the mother's abdomen is exposed to radiation from outside her body. (flutrackers.com)
  • Therefore, the types of ious forms of radiation, carcinogen ifested as a higher incidence of the tumours that occur during childhood ic infectious agents, and chemicals same kinds of tumours that occur in in humans, including various embry and chemical mixtures. (who.int)
  • Burns commonly occur by direct or indirect contact with heat, electric current, radiation, or chemical agents. (stlukes-stl.com)
  • Common radiation exposures to low dosage of radiation like CT scans or X-rays do not cause ACS. (syndromespedia.com)
  • BACKGROUND: Ionizing radiation is an established carcinogen, but risks from low-dose exposures are controversial. (cdc.gov)
  • Furthermore, the magnitude of the cancer risks from these low-dose radiation exposures was statistically compatible with the radiation dose-related cancer risks of the atomic bomb survivors. (cdc.gov)
  • Exposures like these, especially internally from ingestion and inhalation, would raise their statistical chance of developing cancer, but it would not deliver the huge whole-body-at-once dose you need for acute radiation syndrome. (plainsmenpost.com)
  • Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. (medscape.com)
  • Reduce electromagnetic radiation exposure from your cell phone. (medlineplus.gov)
  • For the purpose of this review, "radiation" refers to ionizing radiation (e.g., x-rays, γ-rays, radionuclides) and not to other forms of radiation (e.g., long-wavelength electromagnetic waves such as radar, microwaves, diathermy and FM radio waves). (cmaj.ca)
  • Ionizing radiation in the form of x-rays and γ-rays are short-wavelength electromagnetic rays. (cmaj.ca)
  • Radiation energy is energy related to ionizing, low-frequency electromagnetic, optical, or radio-frequency electromagnetic radiation. (ccohs.ca)
  • Red light therapy is a term that encompasses both visible red and invisible near-infrared (NIR) wavelengths of electromagnetic radiation. (juvawave.com)
  • It's important to understand the differences between various types of electromagnetic radiation so you can give your clients the best physical therapy results. (juvawave.com)
  • The term "radiation" can be scary, but all light (and all heat) is a form of electromagnetic radiation. (juvawave.com)
  • Internal contamination treatment - These may include potassium iodide, Prussian blue, and diethylenetriamine pentaacetic acid depending on the specific type of radiation. (syndromespedia.com)
  • They also try get more information about the exposure, such as what type of radiation it was, how far away you were from the source of the radiation, and how long you were exposed. (medlineplus.gov)
  • It is determined by multiplying the number of rads by the quality factor, a number reflecting the potential damage caused by the particular type of radiation. (cdc.gov)
  • The time for skin to heal depends on the radiation dose the person's skin received. (cdc.gov)
  • Complete healing of the skin may take from several weeks up to a few years depending on the radiation dose the person's skin received. (cdc.gov)
  • Radiation exposure before birth can increase a person's risk of getting cancer later in life. (flutrackers.com)
  • New areas of neurosurgery were developed: further study of the etiology and pathogenesis of acute cerebrovascular disturbance, diagnostics and surgical treatment of cerebral hemorrhagic strokes (G.P.Pedachenko, L.Ye.Pelekh, O.P.Burlutskyi), study of the pathogenesis and treatment of spinal cord compression, study of the dynamics epileptogenic foci and epilepsy surgery, stereotactic surgery for extrapyramidal hyperkinesia. (kiev.ua)
  • Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal tissue can also be damaged, leading to toxicity. (nature.com)
  • Since invention of the x-ray in 1895, ionizing radiation has been harnessed for diagnostic and therapeutic purposes. (cmaj.ca)
  • The outcome of damage to the organism by ionizing radiation is directly related to the time when the treatment began. (com.hr)
  • We have recently completed a two-year BARDA contract for the continued development of BIO 300 as a pharmacological medical countermeasure (MCM) to ionizing radiation. (humaneticscorp.com)
  • Enhanced Survival in Mice Exposed to Ionizing Radiation by Combination of Gamma-Tocotrienol and Simvastatin. (uams.edu)
  • We therefore conclude that these new epidemiological studies directly support excess cancer risks from low-dose ionizing radiation. (cdc.gov)
  • Whether low-dose ionizing radiation can cause cancer is a critical and long-debated question in radiation protection. (cdc.gov)
  • The cause of ALL / LBL is unknown, but it has been associated with ionizing radiation as well as certain genetic abnormalities. (logicalimages.com)
  • 60 Co (read as cobalt sixty) is used for sterilizing medical equipment and consumer products, radiation therapy for treating cancer patients, manufacturing plastics, and irradiating food. (cdc.gov)
  • Exposure to high levels of cobalt radiation can cause changes in the genetic materials within cells and may result in the development of some types of cancer. (cdc.gov)
  • Other sources are man-made, such as x-rays, radiation therapy to treat cancer, and electrical power lines. (medlineplus.gov)
  • For example, radiation helps medical professionals conduct diagnostic tests and treat certain health problems such as cancer in the health sector. (forthepeople.com)
  • It should be noted that although radiation can help treat cancer, it can also cause cancer if administered into the human body in high amounts. (forthepeople.com)
  • Co-developed by Israeli startup StemRad and US aerospace company Lockheed Martin, the vest is personal protective equipment for astronauts beyond low Earth orbit (LEO) that noticeably reduces Radiation Exposure Induced Death (REID) such as cancer while eliminating the possibility of Acute Radiation Syndrome (ARS) due to solar particles (SPE. (nocamels.com)
  • The aim of this monograph was to systematically review the potential biases in these studies (including dose uncertainty, confounding, and outcome misclassification) and to assess whether the subset of minimally biased studies provides evidence for cancer risks from low-dose radiation. (cdc.gov)
  • The researchers hope to learn if combining the study drugs with surgery and radiation will get rid of the cancer from participants' prostates and reduce their prostate-specific antigen (PSA) to an undetectable level. (dana-farber.org)
  • Being exposed to a lot of radiation over a short period of time, such as from a radiation emergency , can cause skin burns . (medlineplus.gov)
  • The general population is rarely exposed to radioactive cobalt unless a person is undergoing radiation therapy. (cdc.gov)
  • Alternative causes of ST-segment and T-wave changes are left ventricular aneurysm, pericarditis, Prinzmetal angina, early repolarization, Wolff-Parkinson-White syndrome, and drug therapy (eg, with tricyclic antidepressants, phenothiazines). (medscape.com)
  • Étant donné la rareté de nouvelles études et la faible qualité de plusieurs d'entre elles, l'AETMIS a appuyé en grande partie son évaluation sur des consensus d'experts, dont les deux principaux sont issus de l'Hyperbaric Oxygen Therapy Committee de l'Undersea and Hyperbaric Medical Society (UHMS) et de l'European Committee for Hyperbaric Medicine (ECHM). (bvsalud.org)
  • Based on the results from the Phase 3 KEYNOTE-775/Study 309 trial, KEYTRUDA plus LENVIMA has been approved in the U.S. for patients with advanced endometrial carcinoma that is not microsatellite instability-high or dMMR, who have disease progression following prior systemic therapy in any setting and are not candidates for curative surgery or radiation. (merck.com)
  • Davidson T, Zhang H, Dong H , Grams MP, Park SS, Yan Y. Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint Blockade. (mayo.edu)
  • A patient with impaired immune system like HIV, or one who is undergoing radiation therapy has higher chances of SJS. (targetwoman.com)
  • This three-week study evaluated the intensity of pre- and post-therapy pain in 52 patients with shoulder periarthritis (frozen shoulder), myofascial pain syndrome, or lateral epicondylitis. (juvawave.com)
  • People who receive a high radiation dose also can have skin damage. (cdc.gov)
  • Caused by a critical exposure to radiation, acute radiation syndrome includes neutropenia, nervous system damage, and pneumonia with high fatality rate. (enzychem.com)
  • Exposure to large amounts of radiation from radioactive cobalt can damage cells in your body from the radiation. (cdc.gov)
  • But too much radiation can damage tissues by changing cell structure and damaging DNA. (medlineplus.gov)
  • Fallout that has settled on the ground and building roofs can release this penetrating radiation, and it can then damage cells and tissues in the human body. (centerforhealthsecurity.org)
  • 80 years) veteran controls were collected and evaluated for radiation-induced chromosome damage utilizing directional genomic hybridization (dGH), a cytogenomics-based methodology that facilitates simultaneous detection of translocations and inversions. (allenpress.com)
  • REM relates the absorbed dose in human tissue to the effective biological damage of the radiation. (cdc.gov)
  • ECG can be diagnostic in acute pericarditis and typically shows diffuse ST elevation. (medscape.com)
  • For many children and young adolescents, intermittent viral syndromes with myalgias or athletic overuse are common problems that may have similar presentations to growing pains. (pediatriceducation.org)
  • Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. (uams.edu)
  • Radiation-induced pneumonitis in humans usually becomes apparent approximately two to four months after irradiation exposure, while radiation-induced fibrosis develops six months or more after exposure. (humaneticscorp.com)
  • Stage 4 electrocardiograph changes in the same patient as in the previous image, taken approximately 3 months after acute pericardial illness. (medscape.com)
  • We have found that BIO 300 given prophylactically dramatically increases survival in animal models exposed to an acute dose of lethal radiation. (humaneticscorp.com)
  • Stage 1 electrocardiograph changes in a patient with acute pericarditis. (medscape.com)
  • The ratio of the amplitude of ST segment to the amplitude of the T wave in leads I, V4, V5, and V6 on electrocardiogram can be used to differentiate acute pericarditis (AP) from early repolarization (ER) and early repolarization of left ventricular hypertrophy (ERLVH), according to a recent study. (medscape.com)
  • Acute Radiation Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)