A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
A diminution of the skeletal muscle tone marked by a diminished resistance to passive stretching.
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)
A species of ENTEROVIRUS which is the causal agent of POLIOMYELITIS in humans. Three serotypes (strains) exist. Transmission is by the fecal-oral route, pharyngeal secretions, or mechanical vector (flies). Vaccines with both inactivated and live attenuated virus have proven effective in immunizing against the infection.
Vaccines used to prevent POLIOMYELITIS. They include inactivated (POLIOVIRUS VACCINE, INACTIVATED) and oral vaccines (POLIOVIRUS VACCINE, ORAL).
A species of ENTEROVIRUS infecting humans and containing 11 serotypes, all coxsackieviruses.
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
WHO regional office for the Americas acting as a coordinating agency for the improvement of health conditions in the hemisphere. The four main functions are: control or eradication of communicable diseases, strengthening of national and local health services, education and training, and research.
Organized services to administer immunization procedures in the prevention of various diseases. The programs are made available over a wide range of sites: schools, hospitals, public health agencies, voluntary health agencies, etc. They are administered to an equally wide range of population groups or on various administrative levels: community, municipal, state, national, international.
A genus of the family PICORNAVIRIDAE whose members preferentially inhabit the intestinal tract of a variety of hosts. The genus contains many species. Newly described members of human enteroviruses are assigned continuous numbers with the species designated "human enterovirus".
A mild, highly infectious viral disease of children, characterized by vesicular lesions in the mouth and on the hands and feet. It is caused by coxsackieviruses A.
Inflammation of the spinal cord. Relatively common etiologies include infections; AUTOIMMUNE DISEASES; SPINAL CORD; and ischemia (see also SPINAL CORD VASCULAR DISEASES). Clinical features generally include weakness, sensory loss, localized pain, incontinence, and other signs of autonomic dysfunction.
Infectious disease processes, including meningitis, diarrhea, and respiratory disorders, caused by echoviruses.
A suspension of formalin-inactivated poliovirus grown in monkey kidney cell tissue culture and used to prevent POLIOMYELITIS.
The general name for NORTH AMERICA; CENTRAL AMERICA; and SOUTH AMERICA unspecified or combined.
A mosquito-borne viral illness caused by the WEST NILE VIRUS, a FLAVIVIRUS and endemic to regions of Africa, Asia, and Europe. Common clinical features include HEADACHE; FEVER; maculopapular rash; gastrointestinal symptoms; and lymphadenopathy. MENINGITIS; ENCEPHALITIS; and MYELITIS may also occur. The disease may occasionally be fatal or leave survivors with residual neurologic deficits. (From Joynt, Clinical Neurology, 1996, Ch26, p13; Lancet 1998 Sep 5;352(9130):767-71)
The ongoing, systematic collection, analysis, and interpretation of health-related data with the purpose of preventing or controlling disease or injury, or of identifying unusual events of public health importance, followed by the dissemination and use of information for public health action. (From Am J Prev Med 2011;41(6):636)
The non-profit, non-governmental organization which collects, processes, and distributes data on hospital use. Two programs of the Commission are the Professional Activity Study and the Medical Audit Program.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
A syndrome characterized by headache, neck stiffness, low grade fever, and CSF lymphocytic pleocytosis in the absence of an acute bacterial pathogen. Viral meningitis is the most frequent cause although MYCOPLASMA INFECTIONS; RICKETTSIA INFECTIONS; diagnostic or therapeutic procedures; NEOPLASTIC PROCESSES; septic perimeningeal foci; and other conditions may result in this syndrome. (From Adams et al., Principles of Neurology, 6th ed, p745)
Disease having a short and relatively severe course.
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.
Complete or severe weakness of the muscles of respiration. This condition may be associated with MOTOR NEURON DISEASES; PERIPHERAL NERVE DISEASES; NEUROMUSCULAR JUNCTION DISEASES; SPINAL CORD DISEASES; injury to the PHRENIC NERVE; and other disorders.
Congenital or acquired paralysis of one or both VOCAL CORDS. This condition is caused by defects in the CENTRAL NERVOUS SYSTEM, the VAGUS NERVE and branches of LARYNGEAL NERVES. Common symptoms are VOICE DISORDERS including HOARSENESS or APHONIA.
Refuse liquid or waste matter carried off by sewers.
A specialized agency of the United Nations designed as a coordinating authority on international health work; its aim is to promote the attainment of the highest possible level of health by all peoples.
A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481)
A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)
A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.
Severe or complete loss of facial muscle motor function. This condition may result from central or peripheral lesions. Damage to CNS motor pathways from the cerebral cortex to the facial nuclei in the pons leads to facial weakness that generally spares the forehead muscles. FACIAL NERVE DISEASES generally results in generalized hemifacial weakness. NEUROMUSCULAR JUNCTION DISEASES and MUSCULAR DISEASES may also cause facial paralysis or paresis.
The concept pertaining to the health status of inhabitants of the world.
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
A common condition characterized by transient partial or total paralysis of skeletal muscles and areflexia that occurs upon awakening from sleep or less often while falling asleep. Stimuli such as touch or sound may terminate the episode, which usually has a duration of seconds to minutes. This condition may occur in normal subjects or be associated with NARCOLEPSY; CATAPLEXY; and hypnagogic HALLUCINATIONS. The pathophysiology of this condition is closely related to the normal hypotonia that occur during REM sleep. (From Adv Neurol 1995;67:245-271)
An autosomal dominant familial disorder characterized by recurrent episodes of skeletal muscle weakness associated with falls in serum potassium levels. The condition usually presents in the first or second decade of life with attacks of trunk and leg paresis during sleep or shortly after awakening. Symptoms may persist for hours to days and generally are precipitated by exercise or a meal high in carbohydrates. (Adams et al., Principles of Neurology, 6th ed, p1483)
Paralysis caused by a neurotropic toxin secreted by the salivary glands of ticks.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
The relationships of groups of organisms as reflected by their genetic makeup.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
An infant during the first month after birth.
A country spanning from central Asia to the Pacific Ocean.
Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE). It can infect birds and mammals. In humans, it is seen most frequently in Africa, Asia, and Europe presenting as a silent infection or undifferentiated fever (WEST NILE FEVER). The virus appeared in North America for the first time in 1999. It is transmitted mainly by CULEX spp mosquitoes which feed primarily on birds, but it can also be carried by the Asian Tiger mosquito, AEDES albopictus, which feeds mainly on mammals.
A species of anaerobic, gram-positive, rod-shaped bacteria in the family Clostridiaceae that produces proteins with characteristic neurotoxicity. It is the etiologic agent of BOTULISM in humans, wild fowl, HORSES; and CATTLE. Seven subtypes (sometimes called antigenic types, or strains) exist, each producing a different botulinum toxin (BOTULINUM TOXINS). The organism and its spores are widely distributed in nature.
An autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. During attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. Episodes last from 15-60 minutes and typically occur after a period of rest following exercise. A defect in skeletal muscle sodium channels has been identified as the cause of this condition. Normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (Adams et al., Principles of Neurology, 6th ed, p1481)
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.
A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of SKELETAL MYOCYTES. Defects in the SCN4A gene, which codes for the alpha subunit of this sodium channel, are associated with several MYOTONIC DISORDERS.
Acute flaccid paralysis (AFP) is a clinical manifestation of poliomyelitis characterized by weakness or paralysis and reduced ... "Acute Flaccid Paralysis (AFP)". Public Health Notifiable Disease Management Guidelines. Alberta Government Health and Wellness ... Active surveillance for poliovirus through reporting and laboratory testing of all cases of acute flaccid paralysis. ... Two distinct methods are used in tandem: acute flaccid paralysis (AFP) surveillance and environmental surveillance. Monitoring ...
In 2019, a 4 year old boy was found with acute flaccid paralysis and was found to have an owl's eye appearance. The case also ... Ding, Joy Zhuo; McMillan, Hugh J. (29 July 2019). ""Owl's Eye" Sign in Acute Flaccid Paralysis". Canadian Journal of ... ISBN 978-1-107-63491-6. Sheerin, F.; Collison, K.; Quaghebeur, G. (January 2009). "Magnetic resonance imaging of acute ... "Specific MRI findings help distinguish acute transverse myelitis of Neuromyelitis Optica from spinal cord infarction". Multiple ...
... result in acute flaccid paralysis. This article lists people who had the paralytic form of polio. The extent of paralysis ... "Lis Hartel: Overcoming Paralysis". International Olympic Committee. Retrieved 20 May 2007. "Five Pros for the Future". TIME. 19 ... Symptoms include muscle pain, further weakening of muscles and paralysis. Surviving paralytic polio can be a life-changing ... ISBN 0-405-10224-0. Marc Shell (2005). Polio and its aftermath: the paralysis of culture. Cambridge: Harvard University Press. ...
... this condition is known as acute flaccid paralysis. Depending on the site of paralysis, paralytic poliomyelitis is classified ... Paralytic poliomyelitis may be clinically suspected in individuals experiencing acute onset of flaccid paralysis in one or more ... If poliovirus is isolated from a patient experiencing acute flaccid paralysis, it is further tested through oligonucleotide ... The degree of both acute paralysis and residual paralysis is likely to be proportional to the degree of viremia, and inversely ...
Singh, SS; Manimunda, SP; Sugunan, AP; Sahina, Vijayachari P (2008). "Four cases of acute flaccid paralysis associated with ...
Cases of acute flaccid paralysis (AFP) to be reported in time and stool specimens of them to be collected within 14 days. ... A study observing data till the end of 2017 correlates non-polio acute flaccid paralysis rates with pulse polio frequency in ... "Correlation between Non-Polio Acute Flaccid Paralysis Rates with Pulse Polio Frequency in India". International Journal of ... "Antigenic Diversity of Enteroviruses Associated with Nonpolio Acute Flaccid Paralysis, India, 2007-2009". Emerging Infectious ...
Centers for Disease Control and Prevention (CDC) (2001-10-12). "Public Health Dispatch: Acute Flaccid Paralysis Associated with ...
13 December 2018). "Acute flaccid paralysis (AFP) surveillance intensification for polio certification in Kaduna state, Nigeria ... where surveillance is further defined as the finding and examination of at least one case of nonpolio acute flaccid paralysis ...
No acute flaccid paralysis, no death and no acquisition from a blood transfusion has ever been reported. The Jamestown Canyon ... equal or more than 4-fold change in JCV-specific neutralizing antibody titers between acute and convalescent samples; or 3) JCV ...
... an acute flaccid paralysis syndrome associated with WNV infection, is less common than WNM or WNE. This syndrome is generally ... West-Nile reversible paralysis, Like WNP, the weakness or paralysis is asymmetric. Reported cases have been noted to have an ... Pain sometimes precedes the paralysis. The paralysis can occur in the absence of fever, headache, or other common symptoms ... flaccid paralysis, and hyporeflexia with no sensory abnormalities. West Nile meningitis (WNM) usually involves fever, headache ...
Acute - the most common diseases caused by acute viral infections are encephalitis, flaccid paralysis, aseptic meningitis, post ... and acute flaccid paralysis Poliomyelitis Herpes simplex encephalitis Enteroviral disease Most forms of aseptic meningitis are ... While acute viral diseases come on quickly, chronic viral conditions have long incubation periods inside the body. Their ... most cases occur in those with congenital rubella syndrome Varicella-zoster encephalitis Acute Measles encephalitis Mumps ...
... generally associated with respiratory symptoms while other HBoV tend to be associated with diarrhea and acute flaccid paralysis ... April 2007). "Human bocavirus and acute wheezing in children". Clin. Infect. Dis. 44 (7): 904-10. doi:10.1086/512196. PMID ... 2007). "Identification of a novel polyomavirus from patients with acute respiratory tract infections". PLOS Pathog. 3 (5): e64 ... "Detection of a bocavirus circular genome in fecal specimens from children with acute diarrhea in Beijing, China". PLOS One. 7 ( ...
Acute flaccid myelitis: a polio-like syndrome that causes muscle weakness and paralysis. Poliomyelitis: disease caused by viral ... Inflammation in the spinal cord, can cause the myelin and axon to be damaged resulting in symptoms such as paralysis and ... Particular benefit has been shown with patients who are in the acute or subacute stage of the myelitis showing active ... Thomas M, Thomas J (February 1997). "Acute transverse myelitis". J la State Med Soc. 149 (2): 75-7. PMID 9055531. Wasay M, Arif ...
... and is associated with acute flaccid paralysis (AFP) - a disease similar to polio. Enterovirus 70: causes outbreaks of acute ...
The number of affected districts declined from 23 (including WPV1-positive acute flaccid paralysis [AFP] cases and positive ... The most recent case had onset of paralysis on 8 August/2016, from Kabul. In Afghanistan, the mortality ratio for children ...
2007 to February 2016 and failure of acute flaccid paralysis surveillance to signal Zika emergence in this setting". Bulletin ... facial paralysis or myelitis in 25. However, there was only one laboratory confirmation of Zika virus infection using RT-PCR in ...
Some non-polio types of Enterovirus C have been associated with the polio-like condition AFP (acute flaccid paralysis), ...
They have been associated with gastroenteritis, influenza-like symptoms and non polio associated acute flaccid paralysis in ...
... team who implemented surveillance for acute flaccid paralysis, which is how polio is eradicated. From 2000 to 2003, Ryan was ...
... conducting surveillance through investigation of acute flaccid paralysis cases among children under 15 years old (in order to ...
... or acute flaccid paralysis. Non-neurologic complications such as inflammation of the heart, fluid in the lungs, or bleeding ... Other serious complications of HFMD include encephalitis (inflammation of the brain), or flaccid paralysis in rare ... Most cases of the disease are relatively harmless, but complications including encephalitis, meningitis, and paralysis that ... Identifying and managing an acute viral syndrome". Cleve Clin J Med. 81 (9): 537-43. doi:10.3949/ccjm.81a.13132. PMID 25183845 ...
Bengaluru is one of the centres under National Polio Surveillance Programme conducting surveillance of acute flaccid paralysis ... First detection of human meta-pneumovirus from acute pneumonia cases in India. Discovered Chandipura virus involvement in ... Subsequently, studies on Acquired Immune Deficiency Syndrome (AIDS), Rotavirus gastroenteritis, acute haemorrhagic ...
... demonstration of a novel SMS-based smartphone application to improve acute flaccid paralysis (AFP) surveillance in Nigeria" ( ...
... a family of proteins with fungicidal activity Atypical facial pain Acute flaccid paralysis, a clinical manifestation ... characterized by paralysis and reduced muscle tone Active fire protection Artilleriefährprahm, a German gunboat of World War II ...
... acute flaccid paralysis, and the related acute flaccid myelitis. Enteroviruses are members of the picornavirus family, a large ... Acute hemorrhagic conjunctivitis can be caused by enteroviruses. Herpangina is caused by Coxsackie A virus, and causes a ... Type B enteroviruses are responsible for a vast number of mild and acute infections. They have been reported to remain in the ... However genome mutations, which enterovirus B serotypes may acquire in the host during the acute phase, may transform these ...
... understanding the mechanism of enterovirus D68 associated acute flaccid myelitis suggests multiple means by which paralysis may ... These mice exhibited all symptoms and pathology of poliomyelitis observed in humans including flaccid paralysis and spinal cord ... "Transgenic Mouse Model for Echovirus Myocarditis and Paralysis". Proceedings of the National Academy of Sciences of the United ...
Guillian-Barré Syndrome is a class of acute polyneuropathies which present with flaccid paralysis, they include acute ... followed by an ascending flaccid paralysis caused by an acute inflammatory demyelinating neuropathy after several more weeks. ... AIDP, which represents the vast majority of Guillian-Barré cases, classically presents with an acute onset, ascending paralysis ... During acute infection both direct peripheral nervous involvement, most commonly bilateral facial palsy, and an acute ...
The term acute flaccid paralysis (AFP) is often used to describe an instance with a sudden onset, as might be found with polio ... "flaccid paralysis - definition of flaccid paralysis in the Medical dictionary - by the Free Online Medical Dictionary, ... Idris M, Elahi M, Arif A (Jan-Mar 2007). "Guillain Barre syndrome: the leading cause of acute flaccid paralysis in Hazara ... "Public Health Dispatch: Acute Flaccid Paralysis Associated with Circulating Vaccine-Derived Poliovirus --- Philippines, 2001". ...
"An Update on Outbreak of Paralysis in US: Acute Flaccid Myelitis". The transverse myelitis association. 2014-10-16. Archived ... Bitnun, A; Yeh, EA (29 June 2018). "Acute Flaccid Paralysis and Enteroviral Infections". Current Infectious Disease Reports. 20 ... Suresh, Sneha; Forgie, Sarah; Robinson, Joan (2018). "Non‐polio Enterovirus detection with acute flaccid paralysis: A ... Acute flaccid myelitis (AFM) is a serious condition of the spinal cord. Symptoms include rapid onset of arm or leg weakness and ...
Examination of these children showed that many of them had acute flaccid paralysis and areflexia but with little or no sensory ... Acute motor axonal neuropathy (AMAN) is a variant of Guillain-Barré syndrome. It is characterized by acute paralysis and loss ... She developed acute paralysis and respiratory failure. Investigators discovered that several of the chickens in the home ... Every summer, hundreds of children from rural China developed acute paralysis and respiratory failure. Hospitals were ...
Performance of acute flaccid paralysis (‎AFP)‎ surveillance and incidence of poliomyelitis (‎data received in WHO Headquarters ... PERFORMANCE OF ACUTE FLACCID PARALYSIS (‎AFP)‎ SURVEILLANCE AND INCIDENCE OF POLIOMYELITIS, 2004-2005 (‎DATA RECEIVED IN WHO ... Performance of acute flaccid paralysis (‎AFP)‎ surveillance and incidence of poliomyelitis, 2017- Fonctionnement de la ... 1993)‎. Acute onset flaccid paralysis. Geneva : World Health Organization. http://www.who.int/iris/handle/10665/61626 ...
... associated acute flaccid paralysis (AFP) due to spinal cord anterior horn cell disease. Emphasis is placed on the epidemiology ... Acute flaccid paralysis Acute flaccid myelitis Enterovirus D68 Enterovirus A71 Poliovirus Poliomyelitis Vaccine-derived ... Acute flaccid paralysis associated with novel enterovirus C105. Emerg Infect Dis. 2015;21(10):1858-60.CrossRefPubMed ... A cluster of acute flaccid paralysis and cranial nerve dysfunction temporally associated with an outbreak of enterovirus D68 in ...
Number of cases of acute flaccid paralysis with anterior myelitis (N = 23), by month of neurologic symptom onset - California, ... Acute Flaccid Paralysis with Anterior Myelitis - California, June 2012-June 2014. Patrick Ayscue, DVM1,2, Keith Van Haren, MD3, ... Acute flaccid paralysis (AFP) with anterior myelitis is not a reportable condition, and baseline rates of disease are unknown ... Alternate Text: The figure above is a bar chart showing the number of cases of acute flaccid paralysis with anterior myelitis ( ...
Acute Flaccid Paralysis Associated with Circulating Vaccine-Derived Poliovirus --- Philippines, 2001 Three cases of acute ... flaccid paralysis (AFP) associated with circulating vaccine-derived poliovirus (cVDPV) isolates were reported in the ... of paralysis on March 15. A second child, aged 3 years from Laguna province on Luzon island (60 miles south of Manila) who had ... had onset of paralysis on July 26. No patients had traveled outside of their province of residence since birth. ...
Trends in Nonpolio Acute Flaccid Paralysis Incidence in India 2000 to 2013. Neetu Vashisht, Jacob Puliyel, Vishnubhatla ... Although the incidence of polio acute flaccid paralysis (AFP) has decreased in India, the nonpolio AFP (NPAFP) rate has ... Trends in Nonpolio Acute Flaccid Paralysis Incidence in India 2000 to 2013 ... Trends in Nonpolio Acute Flaccid Paralysis Incidence in India 2000 to 2013 ...
... acute flaccid paralysis (AFP) - Raising our voices to improve health around the world. ... Tags acute flaccid paralysis (AFP), Africa, East Africa, FETP, IDSR, Kenya, routine immunization, South Sudan ...
Recent reports in the United States and Canada of acute flaccid paralysis (AFP) in children with detection of EV-D68 in ... Acute flaccid paralysis following enterovirus D68 associated pneumonia, France, 2014 * M Lang1, A Mirand2,3, N Savy1, C ... Acute flaccid paralysis following enterovirus D68 associated pneumonia, France, 2014. Euro Surveill. 2014;19(44):pii=20952. ... Recent reports in the United States and Canada of acute flaccid paralysis (AFP) in children with detection of EV-D68 in ...
SaneVax: Non-polio acute flaccid paralysis, clinically indistinguishable from polio, but twice as deadly. 47,500 new cases in ... Filed Under: India, Polio, Polio Vaccine Injuries, Vaccine Associated Disorders Tagged With: non polio acute flaccid paralysis ... Filed Under: India, Polio Vaccine Injuries, Vaccine Adverse Events Tagged With: non polio acute flaccid paralysis, polio ... SaneVax: Do the 47,500 new cases of acute flaccid paralysis in India mean they traded polio eradication for a disease with ...
There are many physicians who are witnessing an increasing number of children with complex inflammatory & autoimmune conditions, and are beginning to suspect that vaccines may be playing more of a contributing role in the development of these conditions, than what they were previously led to believe. Nonetheless, these physicians dont have a safe forum in which they can discuss their concerns. This film, "THE GREATER GOOD," may be the appropriate medium through which physicians can begin to open up the next phase of dialogue about their growing concerns of vaccine safety & efficacy. ...
Paediatric surveillance of Acute Flaccid Paralysis in the Netherlands in 1997. Pediatrische surveillance van acute slappe ... Home / Documents and publications / Paediatric surveillance of Acute Flaccid Paralysis in the Netherlands in 1997 ...
... ... 2007)‎. Report on the Regional workshop on acute flaccid paralysis and measles surveillance, Cairo, Egypt, 13-15 March 2007. ...
Initial clinical signs and symptoms in patients with acute flaccid paralysis associated with acute West Nile virus infection ... Serologic results for West Nile virus (WNV)-specific antibodies in patients with acute flaccid paralysis associated with acute ... Initial laboratory findings in patients with acute flaccid paralysis associated with acute West Nile virus infectiona ... we evaluated acute flaccid paralysis that developed in seven patients in the setting of acute WNV infection, consecutively ...
Acute Flaccid Paralysis. Figure 6: Saggital (A) and axial (B) T2-weighted magnetic resonance imaging of the cervical spinal ... The work completed by Saad et al. examined 3 individual case studies of acute flaccid paralysis and West Nile virus as well as ... They found that 86% of cases of acute flaccid paralysis due to West Nile virus occurred in people over the age of 40, and 35 ... "Acute Flaccid Paralysis of the Upper Limbs Associated with West Nile Virus Infection." Eur Neurol. 2005; 54(3):159-60. 7. ...
Our findings emphasize the need for active surveillance for acute flaccid myelitis. ... We tested for enterovirus D68 in fecal samples collected during June-September 2016 from 567 patients with acute flaccid ... paralysis in 7 West Africa nations. Children <5 years old comprised 64.3% of enterovirus D68 positive patients. ... Enterovirus D68 Subclade B3 in Children with Acute Flaccid Paralysis in West Africa, 2016 Amary Fall, Ndack Ndiaye, Kevin ...
Sudan , Information resources , Other publications , Weekly acute flaccid paralysis surveillance reports Section menu. You are ...
Dr. Benjamin Greenberg received his Bachelor of Arts degree from Johns Hopkins University and his Masters Degree in Molecular Microbiology and Immunology from the Johns Hopkins School of Public Health in Baltimore, Maryland. He attended medical school at Baylor College of Medicine in Houston, Texas. Then, he completed an internship in medicine at Rush Presbyterian-St. Lukes Medical Center in Chicago, Illinois before going on to his residency in neurology at The Johns Hopkins Hospital in Baltimore, MD. He then joined the faculty within the division of neuroimmunology at Hopkins and became the co-director of the Transverse Myelitis Center and director of the Encephalitis Center. In January of 2009 he was recruited to the faculty at the University of Texas Southwestern Medical Center where he was named Deputy Director of the Multiple Sclerosis Program and Director of the new Transverse Myelitis and Neuromyelitis Optica Program. That same year he established the Pediatric Demyelinating Disease ...
Surveillance of acute flaccid paralysis in Hong Kong: 1997 to 2002. RMK Lam, THF Tsang, KY Chan, YL Lau, WL Lim, TH Lam, NK ... The acute flaccid paralysis notification rate consistently exceeded 1.0 per 100 000 population below 15 years of age. The ... Of 120 children with acute flaccid paralysis reported between 1997 and 2002, 42% were younger than 5 years of age. None of the ... Hong Kong should remain vigilant for acute flaccid paralysis. The effective surveillance system and its evaluation may serve as ...
The WHO country office in Egypt organized training on acute flaccid paralysis (AFP) for surveillance officers under the ... 27 November 2016 - The WHO country office in Egypt organized training on acute flaccid paralysis (AFP) for surveillance ...
WHO in collaboration with partners rolls out a mobile-based surveillance application for Acute Flaccid Paralysis (AFP) to ... WHO in collaboration with partners rolls out a mobile-based surveillance application for Acute Flaccid Paralysis (AFP) to ... WHO in collaboration with partners rolls out a mobile-based surveillance application for Acute Flacc... ...
A 5-year study of human parechoviruses in children living in bad sanitation conditions and non-polio acute flaccid paralysis ... Ken Tyler, A New Polio? EVD68-Associated Acute Flaccid Myelitis (AFM). Date: Tuesday, 12 17, 2019; Speaker: Dr. Erin Beck, ...
A variety of viruses can cause acute flaccid paralysis (AFP). However, the causative agent, sometimes, remains undetermined. ... Ooi MH, Wong SC, Clear D et al (2003) Adenovirus type 21-associated acute flaccid paralysis during an outbreak of hand-foot-and ... Junttila N, Lévêque N, Kabue JP et al (2007) New enteroviruses, EV-93 and EV-94, associated with acute flaccid paralysis in the ... Saad M, Youssef S, Kirschke D et al (2005) Acute flaccid paralysis: the spectrum of a newly recognized complication of West ...
Molecular Characterization of Enteroviruses Isolated from Acute Flaccid Paralysis Cases in Poland, 1999-2014 ... Non-polio enteroviruses associated with acute flaccid paralysis (AFP) and facial paralysis (FP) cases in Romania, 2001-2008. ... Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis, 1998-1999 (as of 25 November 1999). ... Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis, 1998-1999 (as of 4 March 1999). ...
An acute flaccid paralysis surveillance-based serosurvey of poliovirus antibodies in Western Uttar Pradesh, India ... Serum IgG and IgA levels in polio and non-polio acute flaccid paralysis cases in western Uttar Pradesh, India. Indian ... Serum IgG and IgA levels in polio and non-polio acute flaccid paralysis cases in Western Uttar Pradesh, India. Indian ... Acute flaccid paralysis surveillance in bosnia and herzegovina: Recent isolation of two sabin like type 2 poliovirus. Journal ...
Performance of acute flaccid paralysis (‎AFP)‎ surveillance and incidence of poliomyelitis (‎data received in WHO Headquarters ... Performance of acute flaccid paralysis (‎AFP)‎ surveillance and incidence of poliomyelitis, 2017- Fonctionnement de la ... Performance of acute flaccid paralysis (‎AFP)‎ surveillance and incidence of poliomyelitis, 2017 -Fonctionnement de la ... 2001)‎. Sub-regional workshop on enhanced surveillance of acute flaccid paralysis and poliomyelitis : report on a WHO meeting, ...
... of wastewater has been expanded alongside surveillance for acute flaccid paralysis (AFP). ES is a... ... Surveillance for acute flaccid paralysis. Cases of AFP in all children aged , 15 years and suspected cases of poliomyelitis in ... Differential diagnosis of acute flaccid paralysis and its role in poliomyelitis surveillance. Epidemiol Rev. 2000;22(2):298-316 ... Population sensitivity of acute flaccid paralysis and environmental surveillance for serotype 1 poliovirus in Pakistan: an ...
Keywords: Acute flaccid paralysis, ELISA, ITD, RT-PCR, Poliovirus, Sabin Abstract. Background: Sensitive poliovirus ... Sabin and wild type polioviruses from children who presented with acute flaccid paralysis in Nigeria * AO Adedeji ... of 120 fecal samples were randomly collected from children under the age of five who presented with acute flaccid paralysis. ...
October 24, 2018 at 02:18 PM in Acute flaccid myelitis, Acute flaccid paralysis, Childrens health , Permalink , Comments (0) ... November 01, 2018 at 09:35 AM in Acute flaccid myelitis, Acute flaccid paralysis, Childrens health, Culture and health, Health ... July 13, 2018 at 06:50 AM in Acute flaccid paralysis, Cholera, Lassa fever, Measles, Meningitis , Permalink , Comments (0) ... July 11, 2018 at 07:04 AM in Acute flaccid paralysis, Polio, Public health, Surveillance, Vaccination, Vaccines , Permalink , ...
Ninety six health care professionals were registered to receive SMS reminders to report any case of acute flaccid paralysis. ... High quality acute flaccid paralysis (AFP) surveillance is required to maintain polio-free status of a country. Papua New ... From: Using short-message-service notification as a method to improve acute flaccid paralysis surveillance in Papua New Guinea ...
"Genomic characterization of coxsackievirus type A24 strains associated with acute flaccid paralysis and rarely identified ... New enteroviruses, EV-93 and EV-94, associated with acute flaccid paralysis in the Democratic Republic of the Congo ... Polioviruses and other enteroviruses isolated from faecal samples of patients with acute flaccid paralysis in Australia, 1996- ... Genomic characterization of coxsackievirus type A24 strains associated with acute flaccid paralysis and rarely identified ...
Surveillance for acute flaccid paralysis (AFP) is the foundation of the polio eradication initiative since it provides ... date of onset of paralysis, and date of investigation, respectively. Seventy-one percent of the clinicians at the AFP focal ... Table 4 Knowledge of clinicians (acute flaccid paralysis (AFP) focal persons) on case definition of AFP and procedures for ... From: Polio eradication in Nigeria: evaluation of the quality of acute flaccid paralysis surveillance documentation in Bauchi ...
  • In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior myelitis (i.e., evidence of inflammation of the spinal cord involving the grey matter including anterior horn cell bodies) and no history of international travel during the month before symptom onset. (cdc.gov)
  • Three cases of acute flaccid paralysis (AFP) associated with circulating vaccine-derived poliovirus (cVDPV) isolates were reported in the Philippines during March 15--July 26, 2001. (cdc.gov)
  • da Silva EE, Winkler MT, Pallansch MA (1996) Role of enterovirus 71 in acute flaccid paralysis after the eradication of poliovirus in Brazil. (springer.com)
  • In view of the recent circulation of imported wild poliovirus in Bulgaria, the WHO Regional Office for Europe convened a Subregional Workshop on Enhanced Surveillance of Acute Flaccid Paralysis (‎AFP)‎ and Poliomyelitis. (who.int)
  • Acute flaccid paralysis is the major clinical manifestation of poliovirus infection, occurring in 0.1 per cent to one per cent of infections. (health.gov.au)
  • The Australian National Poliovirus Reference Laboratory (NPRL) is accredited by the World Health Organization (WHO) for the testing of stool specimens from cases of acute flaccid paralysis (AFP), a major clinical presentation of poliovirus infection. (health.gov.au)
  • Poliovirus infection is confirmed by virus culture of stool specimens from AFP cases as other conditions that present with acute paralysis can mimic polio. (health.gov.au)
  • The World Health Organization (WHO) polio eradication program is based on maintaining high levels of polio vaccine coverage, clinical surveillance for cases of acute flaccid paralysis (AFP) in children less than 15 years of age and laboratory confirmation of poliovirus infection by testing stool specimens from AFP cases at a laboratory accredited by the WHO for the purpose. (health.gov.au)
  • Unvaccinated individuals who are exposed to poliovirus are at higher risk for acute flaccid myelitis. (medlineplus.gov)
  • Background: The Ministry of health in Oman routinely collects surveillance data for acute flaccid paralysis (AFP) as recommended by the World Health Organization (WHO) as part of polio eradication efforts to detect wild poliovirus infection. (jacobspublishers.com)
  • These vaccine-derived poliovirus infections were detected through the Acute Flaccid Paralysis Surveillance system, monitored by the World Health Organization (WHO). (vactruth.com)
  • to determine the place of acute flaccid paralysis (AFP) surveillance in children of Zaporizhzhia Oblast and laboratory control over the poliovirus circulation, comparing them with the activity of population immunity. (med-expert.com.ua)
  • Isolation of poliovirus from cases of acute flaccid paralysis. (bvsalud.org)
  • Even though poliovirus is still the most common etiologic agent for acute flaccid paralysis in northern India , non polio enteroviruses are also emerging as important causal pathogens in this condition. (bvsalud.org)
  • World Health Organization (WHO) targets for acute flaccid paralysis (AFP) surveillance, including the notification of a minimum rate of AFP among children, are used to assess the adequacy of AFP surveillance for the detection of poliovirus infection. (springer.com)
  • As a result, poliovirus infection is most commonly recognised by the onset of acute flaccid paralysis (AFP). (springer.com)
  • Active surveillance for poliovirus through reporting and laboratory testing of all cases of acute flaccid paralysis. (wikipedia.org)
  • 4 years of age are particularly susceptible to the most severe forms of EV71-associated neurological disease, including meningitis, brain-stem and/or cerebellar encephalitis, and poliomyelitis-like paralysis. (blogspot.com)
  • Whilst the recent EV71 epidemics in South-East Asia suggest a possible source, the acute myelitis observed in the Perth cases is clearly different from the brainstem encephalitis which characterised the severely affected cases in those epidemics. (health.gov.au)
  • The objective of this study is to evaluate the safety, efficacy, and pharmacokinetics of MGAWN1 in subjects with West Nile Fever or a syndrome compatible with West Nile Neuroinvasive Disease (WNND) [encephalitis, meningitis, or acute flaccid paralysis]. (clinicaltrials.gov)
  • To describe the characteristics of patients reported with acute flaccid paralysis between 1997 and 2002, and to evaluate the performance of the acute flaccid paralysis surveillance system using indicators recommended by the World Health Organization. (hkmj.org)
  • All except one of the performance indicators consistently met World Health Organization requirements and thus demonstrated the effectiveness of the acute flaccid paralysis surveillance programme. (hkmj.org)
  • Aim: To compare acute flaccid paralysis (AFP) surveillance systems used by members of the International Network of Paediatric Surveillance Units (INoPSU) across the five AFP surveillance performance indicators recommended by the World Health Organization (WHO) for the maintenance of polio-free certification. (edu.au)
  • Background: Acute Flaccid Paralysis (AFP) was adopted by World Health Organization (WHO) in 1988 as a key pillar used in monitoring progress towards the global polio eradication initiative. (oalibrary.org)
  • Objectives: The aim of this study is to identify the demographic, clinical and epidemiological attributes and quality of acute flaccid paralysis surveillance. (oalibrary.org)
  • Although the incidence of polio acute flaccid paralysis (AFP) has decreased in India, the nonpolio AFP (NPAFP) rate has increased. (aappublications.org)
  • SaneVax: Do the 47,500 new cases of acute flaccid paralysis in India mean they traded polio eradication for a disease with twice the risk of death? (sanevax.org)
  • To evaluate the frequency of isolation of polio and other viruses from fecal samples in subjects with acute flaccid paralysis in northern parts of India . (bvsalud.org)
  • citation needed] Historical records from the 1950s, modern CDC reports, and recent analysis of patterns in India suggest that flaccid paralysis may be caused in some cases by oral polio vaccinations. (wikipedia.org)
  • The controversial declaration comes at a time when India has been experiencing a huge increase in reported cases of non-polio acute flaccid paralysis (NPAFP). (globalresearch.ca)
  • Australia conducts surveillance for cases of acute flaccid paralysis (AFP) in children less than 15 years of age as part of the national polio surveillance program funded by the Australian government. (blogspot.com)
  • There were 60 unique notifications of acute flaccid paralysis (AFP) in 2001, of which 44 were classified by the polio expert committee as eligible non-polio AFP cases, that is, from patients resident in Australia and aged less than 15 years. (health.gov.au)
  • Acute flaccid paralysis (AFP) is defined as a sudden onset of paralysis/weakness in any part of the body of a child less than 15 years of age. (intellectualconcepts.com)
  • Acute flaccid paralysis (AFP) is a clinical syndrome characterized by rapid onset of weakness in a child aged less than 15 years due to any cause when polio is suspected(1). (aku.edu)
  • AFP case was defined as a child aged less than 15 years showing acute onset of flaccid paralysis in one or more limbs, or acute onset of bulbar paralysis [ 4 , 5 ]. (panafrican-med-journal.com)
  • An outbreak of acute flaccid paralysis among children in the United States during summer 2014 was tentatively associated with enterovirus D68 infection. (poliohealth.org.au)
  • In July-December 2018, an outbreak of polio-like acute flaccid myelitis (AFM) occurred in Zhejiang province, China. (frontiersin.org)
  • This includes collection of two stool samples within fourteen days of onset of paralysis and identification of virus, and control of the outbreak and strengthening immunization in that area. (wikipedia.org)
  • Children were recruited by age group (6-11 months, 12-24 months, and 25-69 months) from among cases reported through the acute flaccid paralysis surveillance system between November 2008 and August 2009. (eurekamag.com)
  • This paper accesses the quality of the Acute Flaccid Paralysis (AFP) surveillance system in Edo state using the May/June 2017 Rapid Surveillance Assessment tool for reviewing existing surveillance systems. (escipub.com)
  • Recognition and management of acute flaccid myelitis in children. (springer.com)
  • A second child, aged 3 years from Laguna province on Luzon island (60 miles south of Manila) who had received 3 OPV doses, presented with signs of meningitis but no paralysis on July 23. (cdc.gov)
  • EV-A71 has been shown to play a role as a major causative agent in most neurological diseases except for Guillain-Barré syndrome (GBS), acute disseminated encephalomyelitis (ADEM), and meningitis. (cdc.gov)
  • From 1988 to 2001, three of 186 pediatric patients with acute bacterial meningitis presented with acute flaccid paralysis due to myelopathy. (ncku.edu.tw)
  • Symmetric proximal muscle weakness without sensory symptoms or signs and with preserved reflexes:- Acute myopathy (eg. (docstudents.com)
  • Inflammation of the gray matter in the spinal cord leads to muscle weakness and paralysis. (medlineplus.gov)
  • [1] In about 0.5 percent of cases, it moves from the gut to affect the central nervous system and there is muscle weakness resulting in a flaccid paralysis . (wikipedia.org)
  • So far in 2018, there have been 28 cases of acute flaccid paralysis (AFP) in England, the majority of which have been reported since September. (telegraph.co.uk)
  • Aurora, Colo. (Feb. 26, 2018) - A team of doctors and scientists from the U.S. and Europe led by Kevin Messacar, MD , an infectious disease specialist from Children's Hospital Colorado (Children's Colorado), has found that Enterovirus D68 (EV-D68) is a likely cause of Acute Flaccid Myelitis (AFM), a rare illness that affects the nervous system of children. (evesdrift.com)
  • Surveillance for acute flaccid paralysis, a clinical manifestation of poliomyelitis, is coordinated at VIDRL in collaboration with the Australian Paediatric Surveillance Unit. (health.gov.au)
  • Acute flaccid paralysis (AFP) is a common clinical manifestation of poliomyelitis. (news-medical.net)
  • Acute flaccid paralysis (AFP) is a clinical manifestation of poliomyelitis characterized by weakness or paralysis and reduced muscle tone without other obvious cause (e.g., trauma) among children less than fifteen years old. (wikipedia.org)
  • SaneVax: Non-polio acute flaccid paralysis, clinically indistinguishable from polio, but twice as deadly. (sanevax.org)
  • In a 2012 article published in a medical ethics journal, the doctors stated, "Clinically indistinguishable from polio paralysis but twice as deadly, the incidence of NPAFP was directly proportional to doses of oral polio received. (globalresearch.ca)
  • Acute flaccid myelitis: a clinical review of US cases 2012-2015. (springer.com)
  • None of the cases were acute poliomyelitis or polio-compatible. (hkmj.org)
  • Singh SS, Manimunda SP, Sugunan AP et al (2008) Four cases of acute flaccid paralysis associated with chikungunya virus infection. (springer.com)
  • A serosurvey was conducted among cases of acute flaccid paralysis in the 25 high-polio-incidence districts of western Uttar Pradesh. (eurekamag.com)
  • A recent report on ProMED announced that the acute flaccid paralysis (AFP) surveillance program in Australia had identified EV71 in 36% of AFP cases referred, a finding that highlights the potential virulence of this emerging pathogen. (centerforhealthsecurity.org)
  • Secondly, at least 80% of AFP cases should have two specimens collected within 14 days of onset of paralysis, 24 hours apart, even if the clinician involved is confident of an alternative diagnosis. (health.gov.au)
  • Follow-up information on the presence of residual paralysis at 60-days after diagnosis is available on 50 (45%) of the 111 cases. (health.gov.au)
  • Of the 50 cases for whom follow-up information was available, 25 (50%) had residual paralysis at 60 days and one child with Transverse Myelitis died. (health.gov.au)
  • ProMed Mail carried a report over the weekend from Professor Bruce Thorley of the National Enterovirus Reference Laboratory in Australia that described 5 recent cases of acute flaccid paralysis ( AFP ) in children who tested positive for the EV71 virus . (blogspot.com)
  • According to the same report, there were also 175 cases of "vacine-derived polioviruses (cVDPVs)" detected in people with AVP (acute flaccid paralysis) in six countries. (vactruth.com)
  • In the United States there have been more than 400 cases of the disease - known as acute flaccid myelitis - since 2014. (telegraph.co.uk)
  • This article published in Communicable Diseases Intelligence Volume 23, No 7, 8 July 1999 contains a report on the 6 cases of acute flaccid paralysis identified in Perth, Western Australia since March 1999 (2 in March, 2 in April, 1 in May and 1 in June). (health.gov.au)
  • There have been 6 cases of acute flaccid paralysis (AFP) identified in Perth, Western Australia since March 1999 (2 in March, 2 in April, 1 in May and 1 in June). (health.gov.au)
  • Three of the 6 cases have residual weakness 1-2 months after illness onset and 1 case remains in hospital with prolonged flaccid paralysis requiring ventilation. (health.gov.au)
  • we reviewed all reported acute flaccid paralysis (AFP) cases from 19 countries in the ESA sub region with the date of onset of paralysis from 1 January 2012 to 31 December 2019. (cdc.gov)
  • Thus given the gaps in AFP surveillance as identified in the cases of late notification, this study was designed to explore the reasons and circumstances responsible for late notification of AFP and collection of inadequate stools (more than 14 days of onset of paralysis until collection of the 2nd stool specimen) of AFP cases in health facilities equipped to manage AFP cases. (panafrican-med-journal.com)
  • Despite the promising scenario, it is important to guarantee high quality acute flaccid paralysis surveillance, as there is a risk of importation of cases from areas where the disease is endemic [ 1 ]. (panafrican-med-journal.com)
  • Two stool samples 24 - 48 hours apart from a total of 1184 AFP cases were collected within 14 days of onset of paralysis with the prior oral/verbal informed consent and transported to the national polio laboratory under reverse cold chain. (oalibrary.org)
  • Three cases of acute flaccid paralysis (AFP) with preceding fever are described. (elsevier.com)
  • Due to the advanced stage of polio eradication, the possible role of non-polio enteroviruses (NPEVs) associated to acute flaccid paralysis (AFP) cases has been highlighted. (iec.gov.br)
  • Monitoring of suspected cases of poliomyelitis is carried out with Acute Flaccid Paralysis (AFP) surveillance in Turkey. (akjournals.com)
  • Methods: A data-linkage study for the period from 1 January 2005 to 31 December 2008 compared 165 non-polio AFP cases classified by the Polio Expert Panel with 880 acute neurological presentations potentially compatible with AFP documented in the Australian and New Zealand Paediatric Intensive Care (ANZPIC) Registry. (edu.au)
  • In 2004, 12,000 cases of non-polio paralysis were reported but that number had increased by 2012 to 53,563 cases for a national rate of 12 per 100,000 children. (globalresearch.ca)
  • Saeed M, Zaidi SZ, Naeem A et al (2007) Epidemiology and clinical findings associated with enteroviral acute flaccid paralysis in Pakistan. (springer.com)
  • Through this course, Occupational Therapists and Physical Therapists will develop an increased awareness of acute flaccid myelitis (AFM) including epidemiology, history, probable causative agents, pathogenesis and clinical manifestations. (ceufast.com)
  • The Atheltic Trainer who comes encounters a patient with Acute Flaccid Myelitis, either in their work setting or in the community, will develop an increased awareness including epidemiology, history, probably causative agents, pathogenesis and clinical manifestations allowing them to make the correct referrals to the appropriate healthcare professionals. (ceufast.com)
  • On 14 September 2019, VDPV2 was confirmed in one three-year-old child with Acute Flaccid Paralysis (AFP) symptoms, from Lanao del Sur (Mindanao). (typepad.com)
  • Flaccid symmetric quadriparesis (+/- bulbar and respiratory involvement) with areflexia and minimal to profound sensory loss (but often sensory symptoms)- Acute neuropathy or polyradiculopathy (esp. (docstudents.com)
  • Symptoms included acute flaccid limb weakness and cranial nerve dysfunction. (frontiersin.org)
  • Called acute flaccid paralysis, it can produce polio-like symptoms. (latimes.com)
  • Acute flaccid myelitis of unknown etiology in California, 2012-2015. (springer.com)
  • Recent reports in the United States and Canada of acute flaccid paralysis (AFP) in children with detection of EV-D68 in respiratory samples have raised concerns about the aetiological role of this EV type in severe neurological disease. (eurosurveillance.org)
  • While it is frequently linked to severe outbreaks of HFMD ( Hand, Foot, & Mouth Disease ), EV71 is capable of producing other serious neurological illnesses - including poliomyelitis-like paralysis - as well. (blogspot.com)
  • The neurological complications of EV71 infection may occasionally cause permanent paralysis or death. (blogspot.com)
  • Flaccid paralysis is a neurological condition characterized by weakness or paralysis and reduced muscle tone without other obvious cause (e.g., trauma). (wikipedia.org)
  • however, the exact etiology of this acute flaccid paralysis has not been systematically assessed. (cdc.gov)
  • Because understanding the clinical characteristics and underlying etiology of WNV-induced acute flaccid paralysis is critical for therapeutic decisions as well as prognosis, we describe the detailed clinical, laboratory, and electrophysiologic findings from these six patients and from one additional patient. (cdc.gov)
  • We analyzed the results of acute flaccid paralysis (AFP) surveillance in Korea to assess the quality of AFP surveillance and understand the etiology of non-polio enterovirus (NPEV)-associated central nervous system diseases in a polio-free area. (cdc.gov)
  • However, these reports describe clinical and laboratory features that seem inconsistent with such diagnoses, and the exact cause of acute flaccid paralysis has not been thoroughly assessed with rigorous electrophysiologic, laboratory, and neuroimaging data. (cdc.gov)
  • Accumulated evidence which supports Enterovirus D68 as a likely cause of acute flaccid myelitis will advance prevention and treatment efforts. (evesdrift.com)
  • This highlighted the importance of maintaining physicians' awareness of acute flaccid paralysis surveillance. (hkmj.org)
  • Conditions which may present as AFP include wild and vaccine-acquired poliomyelitis, Guillain-Barr syndrome or transverse myelitis or traumatic paralysis. (health.gov.au)
  • The focus of this review is on enterovirus (EV)-associated acute flaccid paralysis (AFP) due to spinal cord anterior horn cell disease. (springer.com)
  • Acute flaccid myelitis (AFM) is a polio-like disease that results in paralysis in previously healthy persons. (cdc.gov)
  • IMSEAR at SEARO: A Case of Acute Flaccid Paralysis: An Uncommon Presentation of a Common Disease. (who.int)
  • Acute flaccid myelitis (AFM) refers to a polio-like neurologic disease first reported in 2012 in California in a child with evidence of enterovirus D68 in the respiratory tract specimens. (ceufast.com)
  • Like that disease, it mainly strikes children and can cause debilitating paralysis when it infects the nervous system. (popsci.com)
  • A extremely rare tragic disease, acute flaccid paralysis, is played up by media with fear-mongering reporting and diminished perspective. (drbarrydworkin.com)
  • Alberta Government Health and Wellness (2005) Acute Flaccid Paralysis Public Health Notifiable Disease Management Guidelines. (wikipedia.org)
  • The virus "has to start out in your blood and then it gets to the brain, and wherever it stops on the way is what we see," said Dr. Laurene Mascola, chief of the acute communicable disease control program for the Los Angeles County Department of Health Services. (latimes.com)
  • In acute flaccid paralysis, West Nile attacks the same part of the brain that would be damaged by the polio virus, said Dr. Carol Glaser, acting chief of the viral disease section of the state health department. (latimes.com)
  • Acute flaccid paralysis (AFP) is a clinical syndrome characterized by rapid onset of weakness of lower motor neuron type, including weakness of the respiratory and pharyngeal muscles, progressing to maximum severity within several days to weeks. (outbreaknewstoday.com)
  • Of 120 children with acute flaccid paralysis reported between 1997 and 2002, 42% were younger than 5 years of age. (hkmj.org)
  • The most affected age group was children aged 0 to 3 years old where 19,740 children with acute paralysis were reported representing 42.9% of the total reported AFP for the period. (cdc.gov)
  • EV-D68 detection in fecal samples from patients with acute flaccid paralysis in 3 West Africa countries, June to September 2016. (cdc.gov)
  • Methods: A total of 120 fecal samples were randomly collected from children under the age of five who presented with acute flaccid paralysis. (ajol.info)
  • We tested for enterovirus D68 in fecal samples collected during June-September 2016 from 567 patients with acute flaccid paralysis in 7 West Africa nations. (cdc.gov)
  • To thoroughly describe the clinical, laboratory, and electrodiagnostic features of this paralysis syndrome, we evaluated acute flaccid paralysis that developed in seven patients in the setting of acute WNV infection, consecutively identified in four hospitals in St. Tammany Parish and New Orleans, Louisiana, and Jackson, Mississippi. (cdc.gov)
  • Less frequently, acute WNV infection has been associated with acute flaccid paralysis, which has been attributed to Guillain-Barré syndrome, motor axonopathy, or axonal polyneuropathy ( 4 - 6 ). (cdc.gov)
  • Brief descriptions of six patients have suggested that this flaccid paralysis is due to anterior horn cell involvement with a resultant poliomyelitis-like syndrome ( 7 - 9 ). (cdc.gov)
  • A common cause of flaccid paralysis is anterior spinal artery syndrome, in which the anterior spinal artery is blocked. (brainandspinalcord.org)
  • Acute flaccid paralysis (AFP) is a complex clinical syndrome with a broad array of potential etiologies that vary with age. (poliohealth.org.au)
  • Neuroparalytic snakebite and Guillain Barre syndrome were the most common causes of acute flaccid paralysis in adults in our study. (poliohealth.org.au)
  • In February 2014 I wrote about children in California who developed a poliomyelitis-like paralysis, also called acute flaccid paralysis or AFP. (virology.ws)
  • Microarray studies performed using RNA isolated from acute and convalescent whole blood and colon biopsy samples revealed higher but non-significant TNF-α messenger RNA (mRNA) levels in subjects with acute E. histolytica diarrhea compared with convalescence. (ajtmh.org)
  • AFP is defined as the sudden onset of flaccid paralysis in one or more limbs. (news-medical.net)
  • The term acute flaccid paralysis (AFP) is often used to describe an instance with a sudden onset, as might be found with polio. (wikipedia.org)
  • 27 November 2016 - The WHO country office in Egypt organized training on acute flaccid paralysis (AFP) for surveillance officers under the national Expanded Programme on Immunization, with the collaboration of the Ministry of Health and Population, in Sharm El-Sheikh, from 19 to 24 November 2016. (who.int)
  • 2016). Acute Myeloid Leukaemia complicated by myeloid sarcoma presenting as acute flaccid paralysis. (sljol.info)
  • 2016. Acute Myeloid Leukaemia complicated by myeloid sarcoma presenting as acute flaccid paralysis 20, no. 2: 39-41. (sljol.info)
  • Sensitivity of Acute Flaccid Paralysis Surveillance in Nigeria (2006-2015). (escipub.com)
  • Rapid assessments of acute flaccid paralysis surveillance in seven key polio high risk states in Northern Nigeria. (escipub.com)
  • 15 years) in Nigeria with acute flaccid paralysis (AFP). (researcherslinks.com)
  • All patients had acute onset of asymmetric weakness and areflexia but no sensory abnormalities. (cdc.gov)
  • One patient had a quadriparesis with a florid meningoencephalitic picture and the other two had asymmetric flaccid paralysis with fasciculations at the onset of illness. (elsevier.com)
  • Confirmed AFM is defined as acute focal limb weakness and evidence of distinct abnormalities of the spinal cord gray matter on magnetic resonance imaging (MRI) ( 4 ). (frontiersin.org)
  • In areas in which transmission is occurring, WNV infection should be considered in patients with acute flaccid paralysis. (cdc.gov)
  • Saad M, Youssef S, Kirschke D et al (2005) Acute flaccid paralysis: the spectrum of a newly recognized complication of West Nile virus infection. (springer.com)
  • Paralysis as result of EV71 infection has been a recognized complication of EV71 since at least 1984. (centerforhealthsecurity.org)
  • Acute flaccid myelitis (AFM) is usually caused by infection with a virus. (medlineplus.gov)
  • Acute paralysis in limbs that are flaccid (floppy or limp) are associated with this condition. (brainandspinalcord.org)
  • This report published in Communicable Diseases Intelligence Volume 23, No 5, 13 May 1999 contains information on the active surveillance of acute flaccid paralysis was initiated in Australia in March 1995. (health.gov.au)
  • Clinicians who treat a case of AFP are requested to arrange for collection of 2 stool specimens, due to intermittent virus shedding, within 14 days of the onset of paralysis, notify the case and complete a clinical questionnaire. (health.gov.au)
  • Patients typically had extended hospital stays (median = 17 days), and of 13 patients with available information, all had prolonged paralysis persisting at 60 days follow-up. (cdc.gov)
  • 35.2% of patients were found to have residual paralysis, and 8.5% had died. (aappublications.org)
  • The laboratory is also responsible for testing stool samples from all patients with acute flaccid paralysis (AFP) in Australia. (health.gov.au)
  • The first case-patient, a child aged 8 years from northern Mindanao island (500 miles south of Manila) who had received 3 doses of oral polio vaccine (OPV), had onset of paralysis on March 15. (cdc.gov)
  • Flaccid paralysis is a condition characterized by extreme weakness of muscles and loss of muscle tone. (brainandspinalcord.org)

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