Acute Disease: Disease having a short and relatively severe course.Lentiviruses, Bovine: A subgenus of LENTIVIRUS comprising viruses that produce multi-organ disease with long incubation periods in cattle.Q Fever: An acute infectious disease caused by COXIELLA BURNETII. It is characterized by a sudden onset of FEVER; HEADACHE; malaise; and weakness. In humans, it is commonly contracted by inhalation of infected dusts derived from infected domestic animals (ANIMALS, DOMESTIC).Coxiella burnetii: A species of gram-negative bacteria that grows preferentially in the vacuoles of the host cell. It is the etiological agent of Q FEVER.Infectious Anemia Virus, Equine: A species of LENTIVIRUS, subgenus equine lentiviruses (LENTIVIRUSES, EQUINE), causing acute and chronic infection in horses. It is transmitted mechanically by biting flies, mosquitoes, and midges, and iatrogenically through unsterilized equipment. Chronic infection often consists of acute episodes with remissions.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Virulence: The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.Horses: Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.Encephalomyelitis, Autoimmune, Experimental: An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)Antibodies, Viral: Immunoglobulins produced in response to VIRAL ANTIGENS.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Virus Replication: The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.Mice, Inbred BALB CMolecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.T-Lymphocytes: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Lymphocyte Activation: Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Mice, Inbred C57BLBase Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Methimazole: A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.Antithyroid Agents: Agents that are used to treat hyperthyroidism by reducing the excessive production of thyroid hormones.DenmarkPancreatitis, Acute Necrotizing: A severe form of acute INFLAMMATION of the PANCREAS characterized by one or more areas of NECROSIS in the pancreas with varying degree of involvement of the surrounding tissues or organ systems. Massive pancreatic necrosis may lead to DIABETES MELLITUS, and malabsorption.Immunoglobulins, Thyroid-Stimulating: Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.BooksRespiration, Artificial: Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).Forced Expiratory Volume: Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.Respiratory Function Tests: Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.Electronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Food Dispensers, Automatic: Mechanical food dispensing machines.Editorial Policies: The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Postal Service: The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Leukemia, Myeloid: Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.MEDLINE: The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.Polycystic Kidney Diseases: Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.Nephrons: The functional units of the kidney, consisting of the glomerulus and the attached tubule.
Rational sequence of tests for pancreatic function. (1/20367)
Of 144 patients with suspected pancreatic disease in whom a 75Se-selenomethionine scan was performed, endoscopic retrograde pancreatography (ERP) was successful in 108 (75%). The final diagnosis is known in 100 patients and has been compared with scan and ERP findings. A normal scan reliably indicated a normal pancreas, but the scan was falsely abnormal in 30%. ERP distinguished between carcinoma and chronic pancreatitis in 84% of cases but was falsely normal in five patients with pancreatic disease. In extrahepatic biliary disease both tests tended to give falsely abnormal results. A sequence of tests to provide a rapid and reliable assessment of pancreatic function should be a radio-isotope scan, followed by ERP if the results of the scan are abnormal, and a Lundh test if the scan is abnormal but the findings on ERP are normal. (+info)Activation of alveolar macrophages in lung injury associated with experimental acute pancreatitis is mediated by the liver. (2/20367)
OBJECTIVE: To evaluate (1) whether alveolar macrophages are activated as a consequence of acute pancreatitis (AP), (2) the implication of inflammatory factors released by these macrophages in the process of neutrophil migration into the lungs observed in lung injury induced by AP, and (3) the role of the liver in the activation of alveolar macrophages. SUMMARY BACKGROUND DATA: Acute lung injury is the extrapancreatic complication most frequently associated with death and complications in severe AP. Neutrophil infiltration into the lungs seems to be related to the release of systemic and local mediators. The liver and alveolar macrophages are sources of mediators that have been suggested to participate in the lung damage associated with AP. METHODS: Pancreatitis was induced in rats by intraductal administration of 5% sodium taurocholate. The inflammatory process in the lung and the activation of alveolar macrophages were investigated in animals with and without portocaval shunting 3 hours after AP induction. Alveolar macrophages were obtained by bronchoalveolar lavage. The generation of nitric oxide, leukotriene B4, tumor necrosis factor-alpha, and MIP-2 by alveolar macrophages and the chemotactic activity of supernatants of cultured macrophages were evaluated. RESULTS: Pancreatitis was associated with increased infiltration of neutrophils into the lungs 3 hours after induction. This effect was prevented by the portocaval shunt. Alveolar macrophages obtained after induction of pancreatitis generated increased levels of nitric oxide, tumor necrosis factor-alpha, and MIP-2, but not leukotriene B4. In addition, supernatants of these macrophages exhibited a chemotactic activity for neutrophils when instilled into the lungs of unmanipulated animals. All these effects were abolished when portocaval shunting was carried out before induction of pancreatitis. CONCLUSION: Lung damage induced by experimental AP is associated with alveolar macrophage activation. The liver mediates the alveolar macrophage activation in this experimental model. (+info)Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni. (3/20367)
In murine schistosomiasis mansoni, CD4(+) Th1 and Th2 cells participate in the ovum-induced granulomatous inflammation. Previous studies showed that the interleukin-12 (IL-12)-induced Th1 response strongly suppressed the Th2-cell-mediated pulmonary granuloma development in naive or primed mice. However, liver granulomas were only moderately suppressed in egg-vaccinated, recombinant IL-12 (rIL-12)-treated infected mice. The present study shows that repeated rIL-12 injections given during early granuloma development at 5 to 7 weeks after infection prolonged the Th1 phase and resulted in gamma interferon-mediated suppression of liver granulomas. The timing is crucial: if given at 6 to 8 weeks, during the Th2-dominated phase of florid granuloma growth, the treatment is ineffective. Daily injections of rIL-12 given between 5 and 7.5 weeks during the period of granuloma growth achieved a somewhat-stronger diminution in granuloma growth with less deposition of collagen but caused 60% mortality and liver pathology. In contrast, combined treatment with rIL-12 and anti-IL-4-anti-IL-10 monoclonal antibody (MAb) injections given during the Th2 phase strongly inhibited liver granuloma growth without mortality. The diminished inflammatory response was accompanied by less deposition of collagen in the liver. Moreover, neutralization of endogenous IL-12 by anti-IL-12 MAbs effectively decreased the early Th1 phase (between 5 and 6 weeks after infection) but not the developing Th2 phase (5 to 7 weeks) of granuloma development. These studies indicate that the granulomatous response in infected mice can be manipulated by utilizing the Th1-Th2-subset antagonism with potential salutary results in the amelioration of fibrous pathology. (+info)Delay in presentation of patients with acute stroke to hospital in Oxford. (4/20367)
We identified prospectively all patients (181 patients, 183 episodes) admitted to hospital in Oxford with acute stroke from 1 January to 30 June 1997. Data were inadequate in 30, leaving 153 episodes in 151 patients (63 men, 90 women). Structured interviews were used to investigate the timing of events preceding admission. Most strokes (91%) occurred at home, and 36% of patients were alone. After a median delay of 15 min, 56% called a GP (median 30 min response), 41% an ambulance (median 48 min to admission), and 3% went directly to A&E. Median time from hospital admission to doctor assessment was 69 min. Factors reducing delay were: initially calling an ambulance rather than a GP (p < 0.0001); onset not at home (p < 0.001); symptoms improving between onset and admission (p < 0.002); and altered consciousness (p < 0.002). The stroke was not recognized by 44% of patients, but no significant delay resulted. Overall, 31% were admitted within 3 h of onset, 46% within 6 h. Initial contact with the GP is a major determinant of delay. If acute therapies for stroke become available, GPs should be the primary targets for an educational initiative. (+info)Assessment of swallowing and referral to speech and language therapists in acute stroke. (5/20367)
The best clinical assessment of swallowing following acute stroke, in order to decide whether to refer a patient to a speech and language therapist (SLT), is uncertain. Independently of the managing clinical team, we prospectively investigated 115 patients (51 male) with acute stroke, mean age 75 years (range 24-94) within 72 h of admission, using a questionnaire, structured examination and timed water swallowing test. Outcome variables included referral to and intervention by a speech and language therapist (SLT), dietary modification, respiratory complications and death. Of those patients in whom an SLT recommended intervention, 97% were detected by an abnormal quantitative water swallowing test; specificity was 69%. An SLT was very unlikely to recommend any intervention if the test was normal. Inability to perform a water test and/or abnormality of the test was associated with significantly increased relative risks of death, chest infection and dietary modification. A timed water swallowing test can be a useful test of swallowing and may be used to screen patients for referral to a speech and language therapist after acute stroke. (+info)Chlamydia pneumoniae and atherosclerosis. (6/20367)
OBJECTIVE: To review the literature for evidence that chronic infection with Chlamydia pneumoniae is associated with atherosclerosis and acute coronary syndromes. DATA SOURCES: MEDLINE and Institute of Science and Information bibliographic databases were searched at the end of September 1998. Indexing terms used were chlamydi*, heart, coronary, and atherosclerosis. Serological and pathological studies published as papers in any language since 1988 or abstracts since 1997 were selected. DATA EXTRACTION: It was assumed that chronic C pneumoniae infection is characterised by the presence of both specific IgG and IgA, and serological studies were examined for associations that fulfilled these criteria. Pathological studies were also reviewed for evidence that the presence of C pneumoniae in diseased vessels is associated with the severity and extent of atherosclerosis. DATA SYNTHESIS: The majority of serological studies have shown an association between C pneumoniae and atherosclerosis. However, the number of cases in studies that have reported a positive association when using strict criteria for chronic infection is similar to the number of cases in studies which found no association. Nevertheless, the organism is widely found in atherosclerotic vessels, although it may not be at all diseased sites and is not confined to the most severe lesions. Rabbit models and preliminary antibiotic trials suggest that the organism might exacerbate atherosclerosis. CONCLUSION: More evidence is required before C pneumoniae can be accepted as playing a role in atherosclerosis. Although use of antibiotics in routine practice is not justified, large scale trials in progress will help to elucidate the role of C pneumoniae. (+info)Painful incarcerated hernia following a rugby union lineout. (7/20367)
Discussion related to hernias in sport usually involves the diagnosis and treatment of chronic musculotendinous groin disruption. A case of acute trauma in an incarcerated inguinal hernia, occurring in a rugby union player during a lineout, is presented. The injury arose as a result of a change in the laws of the game. (+info)T lymphocyte adhesion mechanisms within inflamed human kidney: studies with a Stamper-Woodruff assay. (8/20367)
Renal inflammatory conditions are characterized by mononuclear cell recruitment to sites of inflammation. We have developed a modified Stamper-Woodruff assay system to analyze mechanisms of functional T cell adhesion to cryostat sections of renal biopsy material from patients with vasculitic glomerulonephritis (GN) and acute allograft rejection. Peripheral blood T cells adhered to intraglomerular, periglomerular, and tubulointerstitial regions of the cortex. Blocking monoclonal antibodies against tissue expressed ICAM-1, VCAM-1, and the CS-1 domain of fibronectin (CS-1Fn) differentially attenuated T cell adhesion. Glomerular adhesion in vasculitic GN and tubulointerstitial adhesion in acute rejection were particularly sensitive to both anti-ICAM-1 and anti-VCAM-1 antibodies, indicating a prominent role for ICAM-1 and VCAM-1 at glomerular sites in vasculitis and at tubulointerstitial sites in rejection. Furthermore, using KL/4 cells (LFA-1 expressing) and Jurkat cells (VLA-4 expressing), we demonstrated specific LFA-1/ICAM-1- and VLA-4/VCAM-1-mediated interactions within glomerular and tubulointerstitial compartments. Jurkat cells also adhered to VCAM-1-free sites, and binding was inhibitable by anti-CS-1Fn antibody, thereby demonstrating a role for VLA-4/fibronectin interactions especially at intraglomerular sites in acute rejection where VCAM-1 is notably absent. We therefore propose a prominent functional role for ICAM-1, VCAM-1, and CS-1 domain fibronectin in T cell recruitment to the inflamed kidney. (+info)Acute enterocolitis[edit]. Used in fixed combination with chlordiazepoxide in the treatment of acute enterocolitis. However, ... Peptic ulcer disease[edit]. Used in fixed combination with chlordiazepoxide as adjunctive therapy in the treatment of peptic ... With the advent of more effective therapies for the treatment of peptic ulcer disease, antimuscarinics have only limited ... ulcer disease; however, no conclusive data that antimuscarinics aid in the healing, decrease the rate of recurrence, or prevent ...
Juvenile joint diseases[edit]. *Acetylsalicylic acid (aspirin)[note 90]. Notes[edit]. An α indicates the medicine is only on ... For treatment of chronic pulmonary aspergillosis and acute invasive aspergillosis *^ For use in pregnant women and in second- ... Medicines for diseases of joints[edit]. Medicines used to treat gout[edit]. *Allopurinol ... In acute diarrhoea zinc sulfate should be used as an adjunct to oral rehydration salts ...
6.1 Acute attacks. *6.2 Disease-modifying treatments *6.2.1 Relapsing remitting multiple sclerosis ... After that, a whole spectrum of diseases named NMOSD (NMO spectrum diseases) or anti-AQP4 diseases has been accepted.[137] ... Disease-modifying treatments. Relapsing remitting multiple sclerosis. As of 2019, twelve disease-modifying medications are ... The expected future course of the disease depends on the subtype of the disease; the individual's sex, age, and initial ...
Acute disease. An acute disease is a short-lived disease, like the common cold.. Chronic disease. A chronic disease is one that ... but acquired disease can be primary disease.. Acute disease. An acute disease is one of a short-term nature (acute); the term ... hereditary diseases (including both genetic diseases and non-genetic hereditary diseases), and physiological diseases. Diseases ... Subclinical disease. Also called silent disease, silent stage, or asymptomatic disease. This is a stage in some diseases before ...
Acute disease. An acute disease is a short-lived disease, like the common cold.. Chronic disease. A chronic disease is one that ... It also sounds like it could imply secondary disease, but acquired disease can be primary disease.. Acute disease disease of a ... hereditary diseases (including both genetic diseases and non-genetic hereditary diseases), and physiological diseases. Diseases ... Chronic disease disease that is a long-term issue (chronic). Congenital disease disease that is present at birth. It is often, ...
... acute diarrhoeal disease; diabetes mellitus; worm infestation; rheumatic arthritis; and mental and nervous disorders. This ... diseases of pulmonary circulation and other forms of heart disease (6.6%); endocrine and metabolic diseases (5.5%); diseases of ... The leading causes of mortality for all age groups are cerebrovascular diseases (11.6%); ischemic heart disease (9.9%); ... and hypertensive diseases (3.9%). The ten leading causes of morbidity for all age groups are, in decreasing order: malaria; ...
Acute alcohol ingestion Adrenal cortical hyperactivity Cushing's syndrome Severe liver disease Adrenal cortical insufficiency ... Addison's disease Drugs: salicylates, antituberculosis agents Hyperthyroidism Acute stress reaction Hypopituitarism Severe ... Lawrence, Canada". Journal of Wildlife Diseases. 42 (1): 115-32. doi:10.7589/0090-3558-42.1.115. PMID 16699154.. ... Levine R (1986). "Monosaccharides in health and disease". Annual Review of Nutrition. 6: 211-24. doi:10.1146/annurev.nu. ...
Tendon xanthomas; elevated LDL cholesterol; premature heart disease *Fanconi anaemia. Predisposition of acute myeloid leukemia ... Specific diseases[edit]. This article includes a list of references, but its sources remain unclear because it has insufficient ... with the more common diseases consisting of heart disease and cancer.[2] The results of a genetic test can confirm or rule out ... "Orphanet Journal of Rare Diseases. 5: 11. doi:10.1186/1750-1172-5-11. ISSN 1750-1172. PMC 2893117. PMID 20492708.. ...
Indication/disease. Procedure. Acute limb ischaemia. Balloon embolectomy Thrombectomy. Vascular bypass grafting ... Arterial and venous disease treatment by angiography, stenting, and non-operative varicose vein treatment sclerotherapy, ... Vascular surgery is a surgical subspecialty in which diseases of the vascular system, or arteries, veins and lymphatic ... The vascular surgeon is trained in the diagnosis and management of diseases affecting all parts of the vascular system except ...
... acute; 610251; ALDH2 Aldosteronism, glucocorticoid-remediable; 103900; CYP11B1 Alexander disease; 203450; GFAP Alexander ... acute myeloid; 601626; FLT3 Leukemia, acute myeloid; 601626; KIT Leukemia, acute myeloid; 601626; LPP Leukemia, acute myeloid; ... RNF212 Refsum disease; 266500; PEX7 Refsum disease; 266500; PHYH Refsum disease, infantile form; 266510; PEX26 Refsum disease, ... PSEN1 Alzheimer disease-10; 104300; AD10 Alzheimer disease-2; 104310; APOE Alzheimer disease-4; 606889; PSEN2 Alzheimer disease ...
Acute paronychia is usually caused by direct or indirect trauma to the cuticle or nail fold, and may be from relatively minor ... Paronychia is a nail disease that is an often-tender bacterial or fungal infection of the hand or foot where the nail and skin ... Generally acute paronychia is a pyogenic paronychia as it is usually caused by a bacterial infection. When no pus is present, ... Acute paronychia is usually caused by bacteria. Claims have also been made that the popular acne medication, isotretinoin, has ...
"Acute Communicable Disease Control". lacounty.gov. ,first1= missing ,last1= in Authors list (help) "Meningitis , Viral , CDC". ... Bartt, R (December 2012). "Acute bacterial and viral meningitis". Continuum (Minneapolis, Minn.). 18 (6 Infectious Disease): ... While the disease can occur in both children and adults, it is more common in children. During an outbreak in Romania and in ... While the disease can occur in both children and adults it is more common in children. Viral meningitis characteristically ...
Journal of Acute Disease. 2 (2): 92-98. doi:10.1016/S2221-6189(13)60106-7. ...
Journal of Acute Disease. 2 (4): 253-261. doi:10.1016/S2221-6189(13)60140-7. ISSN 2221-6189. Discover Magazine (Nov 2000): The ...
Diseases and disorders[edit]. This list is incomplete; you can help by expanding it. ... The following diseases and disorders are some of those related to genes on chromosome 3: *3-methylcrotonyl-CoA carboxylase ... Acute Myeloid Leukemia (AML). *Alkaptonuria. *Arrhythmogenic right ventricular dysplasia. *Atransferrinemia. *Autism. * ...
"Addison's Disease". National Endocrine and Metabolic Diseases Information Service. Retrieved 14 August 2013. "Etiology of ... Acute adrenal crisis on PubmedHealth Adrenal Crisis on Patient.info Katherine White (28 July 2004). "What to do in an emergency ... This may be the result of either previously undiagnosed or untreated Addison's disease, a disease process suddenly affecting ... "Acute adrenal crisis (Addisonian crisis)". Endocrine Surgery Encyclopedia. UCLA Health System. Retrieved 14 August 2013. " ...
... cardiovascular diseases, inflammatory bowel diseases, and diabetes. Acute inflammation of the muscle cells, as understood in ... Acute appendicitis Acute dermatitis Acute infective meningitis Acute tonsillitis The Dietary Inflammatory Index (DII) is a ... Acne vulgaris Asthma Autoimmune diseases Autoinflammatory diseases Celiac disease Chronic prostatitis Colitis Diverticulitis ... Acute inflammation may be regarded as the first line of defense against injury. Acute inflammatory response requires constant ...
Regimen in Acute Diseases. The Sacred Disease. The Art. Breaths. Law. Decorum. Physician (Ch. 1). Dentition ... Diseases 1. Diseases 2. *L473) Volume VI. Diseases 3. Internal Affections. Regimen in Acute Diseases (Appendix) ...
"The global burden of ischemic heart disease in 1990 and 2010: the Global Burden of Disease 2010 study". Circulation. 129 (14): ... Acute and prolonged intake of high quantities of alcoholic drinks (3-4 or more) increases the risk of a heart attack. Family ... "Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life ... Atherosclerotic disease is not the only cause of myocardial infarction, and it may exacerbate or contribute to other causes. A ...
Hobler, K. (Spring 1998). "Acute and Suppurative Appendicitis: Disease Duration and its Implications for Quality Improvement" ( ... Hobler, K. (Spring 1998). "Acute and Suppurative Appendicitis: Disease Duration and its Implications for Quality Improvement" ( ... "Pelvic inflammatory disease (PID) Symptoms; Diseases and Conditions". Mayo Clinic. Archived from the original on 2015-05-07. ... Acute appendicitis seems to be the end result of a primary obstruction of the appendix. Once this obstruction occurs, the ...
... or acute or chronic ear disease. 4 - Functional level below the standards of "3". A3.1.1. Definition: Unaided hearing loss in ... metabolic and nutritional diseases; diseases of the blood and blood forming tissues; dental conditions; diseases of the breast ... E - The "E" stands for "Eyes". This factor concerns visual acuity and diseases and defects of the eye. S - The "S" stands for " ... H - The "H" stands for "Hearing and Ears". This factor concerns auditory acuity and disease and defects of the ear. ...
... will all help prevent the disease from being transmitted to HCWs and others in the future. Severe acute respiratory syndrome: ... They were therefore unable to adequately protect themselves from the disease, and communication surrounding disease treatment ... causing many HCWs to still get the disease. The study followed 17 HCWs in Toronto hospitals who had developed the disease and ... doctors were not quick to notice and diagnose the disease in its earliest stages, as they were still unsure about the disease's ...
Clinical Infectious Diseases. 49 (9): 1405-10. doi:10.1086/606060. PMID 19788357. Reingardiene, D; Lazauskas, R (2006). "[Acute ... About 1% of those with an acute overdose die while chronic overdoses may have worse outcomes. Older people are at higher risks ... Acute aspirin or salicylates overdose or poisoning can cause initial respiratory alkalosis though metabolic acidosis ensues ... Example of severe poisoning include people with high salicylate blood levels: 7.25 mmol/L (100 mg/dL) in acute ingestions or 40 ...
Lower respiratory infections include various pneumonias, influenzas and acute bronchitis. *^ Diarrheal diseases are caused by ... See also: Intestinal infectious diseases *^ Tropical diseases include Chagas disease, dengue fever, lymphatic filariasis, ... Sexual transmission, with the resulting disease being called sexually transmitted disease. *Oral transmission, Diseases that ... An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection ...
Hodgkin's disease, acute lymphocytic leukemia (ALL). Biological markers. Level lower than expected. 50% ... Health and disease management[edit]. A WHO study estimates that only 50% of patients suffering from chronic diseases in ... Leukemia, Hodgkin's disease, non Hodgkin's. Self-report and parent report. More than one missed dose per month. 35% ... 2002). "Adherence with statin therapy in elderly patients with and without acute coronary syndromes". JAMA. 288 (4): 462-467. ...
Mucosal-associated invariant T cells in autoimmunity, immune-mediated diseases and airways disease. Immunology. May 2016, 148 ( ... CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection. Nature Immunology ... Modulation of autoimmune diseases by interleukin (IL)-17 producing regulatory T helper (Th17) cells. The Indian Journal of ... Immunobiology: the immune system in health and disease 5th ed. New York: Garland Pub. 2001. ISBN 978-0-8153-3642-6. OCLC ...
Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... Acute bronchitis usually gets better on its own-without antibiotics. Antibiotics wont help you get better if you have acute ... Content source: Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases ( ... What is a chest cold (acute bronchitis)?. A chest cold occurs when the airways of the lungs swell and produce mucus in the ...
... disease and emphasizes multijurisdictional foodborne illness investigations in the United States. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... Pathogens that cause acute enteric disease outbreaks can spread by contaminated food or water, direct contact with an ill ... Investigating acute enteric disease outbreaks can be a dynamic and complex undertaking, often involving multiple public health ...
Management of acute graft-versus-host disease Andrea Bacigalupo Divisione Ematologia e Trapianto di Midollo, Ospedale San ... Management of acute graft-versus-host disease * 1. Management of acute graft-versus-host disease Andrea Bacigalupo Divisione ... Teshima, T., Ordemann, R., Reddy, P., Gagin, S., Liu, C., Cooke, K.R. & Ferrara, J.L. (2002b) Acute graft-versus-host disease ... Bolanos-Meade, J. & Vogelsang, G.B. (2005) Novel strategies for steroid-refractory acute graft-versus-host disease. Current ...
Malignant disease is the most common cause of pericardial effusion with tamponade in developed countries; However, tuberculosis ... Drugs & Diseases , Cardiology , Acute Pericarditis Q&A How common is malignant disease in acute pericarditis?. Updated: Apr 02 ... encoded search term (How common is malignant disease in acute pericarditis?) and How common is malignant disease in acute ... Soler-Soler J, Permanyer-Miralda G, Sagrista-Sauleda J. A systematic diagnostic approach to primary acute pericardial disease. ...
Cite this: Methimazole for Graves Disease Linked to Acute Pancreatitis - Medscape - Nov 04, 2019. ... Risk of Acute Pancreatitis Real With Methimazole To further investigate the risk in a large population of methimazole users and ... The frequency of acute pancreatitis in ongoing methimazole users is of a similar magnitude as reported for agranulocytosis," he ... Matching each case with four controls, there was no increased risk of acute pancreatitis for the highest vs lowest quartiles of ...
Murine models of acute neuronopathic Gaucher disease. Ida Berglin Enquist, Christophe Lo Bianco, Andreas Ooka, Eva Nilsson, Jan ... Murine models of acute neuronopathic Gaucher disease. Ida Berglin Enquist, Christophe Lo Bianco, Andreas Ooka, Eva Nilsson, Jan ... Murine models of acute neuronopathic Gaucher disease. Ida Berglin Enquist, Christophe Lo Bianco, Andreas Ooka, Eva Nilsson, Jan ... 2001) in The Metabolic and Molecular Bases of Inherited Disease, eds Scriver CR , Beaudet AL , Sly WS , Valle D (McGraw-Hill, ...
A: Radiograph at disease presentation showing no obvious abnormalities in the midfoot region. B: Fat suppression MRI performed ... Dennis McGonagle, Academic Unit of Musculoskeletal Disease, 2nd Floor, Chapel Allerton Hospital, Chapeltown Road, Leeds LS7 4SA ... 1Academic Unit of Musculoskeletal Disease, Chapel Allerton Hospital, Leeds, U.K. ...
... up-to-date reviews of both the clinical and pathophysiological aspects of acute respiratory failure (ARF) in chronic ... Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease. Lung Biology in Health and Disease. ... Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease. Jean-Philippe Derenne,Thomas Similowski,William A. Whitelaw ... Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease. Jean-Philippe Derenne, Thomas Similowski, William A. ...
Severe Acute Respiratory Syndrome-associated Coronavirus Disease (SARS-CoV) , 2003 Case Definition Revised Jul 1, 2003 (https ... Severe Acute Respiratory Syndrome-associated Coronavirus Disease * 2003 Case Definition Revised Jul 1, 2003 ... wwwn.cdc.gov/nndss/conditions/severe-acute-respiratory-syndrome-associated-coronavirus-disease/case-definition/2003/07/) ... Content source: Centers for Disease Control and Prevention. Office of Public Health Scientific Services (OPHSS). Center for ...
... and more.Discusses special considerations for the care of acute coronary syndromes in the ED and CCU.Offers guidance on the ... life-threatening syndromes.Examines the molecular mechanisms of acute coronary syndromes, inflammation and immunity. Explains ... provide all of the scientific and clinical information needed to facilitate rapid evaluation and immediate management of acute ... management of special populations and chronic patients.Includes guidelines for management of acute coronary syndromes from the ...
... director of the CDCs National Center for Immunization and Respiratory Diseases. ... More cases of a polio-like disease are affecting children, according to the Centers for Disease Control and Prevention. ... www.usatoday.com/story/news/nation-now/2018/10/18/parents-guide-polio-like-paralyzing-disease-acute-flaccid-myelitis/1680621002 ... www.usatoday.com/story/news/nation-now/2018/10/18/parents-guide-polio-like-paralyzing-disease-acute-flaccid-myelitis/1680621002 ...
Acute limb ischemia (ALI) is a pathological condition resulting from a sudden blood interruption (or, at least, from an ... 2018) Acute Peripheral Arterial Disease. In: Crucitti A. (eds) Surgical Management of Elderly Patients. Springer, Cham. * First ... Acute limb ischemia: role of preoperative and postoperative duplex in differentiating acute embolic from thrombotic ischemia. ... Acute limb ischemia ALI Embolectomy Aspiration system Vacuum therapy Hybrid surgery This is a preview of subscription content, ...
Elemental diets in treatment of acute Crohns disease Br Med J (Clin Res Ed) 1981; 282 :144 ... Elemental diets in treatment of acute Crohns disease. Br Med J (Clin Res Ed) 1981; 282 doi: https://doi.org/10.1136/bmj. ... Public Health England: Consultant Medical Virologist or Infectious Diseases Physician with a special interest in Virology ...
Evaluating measurable residual disease in acute myeloid leukemia.. Ravandi F1, Walter RB2,3, Freeman SD4. ... Mounting evidence indicates that the presence of measurable ("minimal") residual disease (MRD), defined as posttherapy ... independent prognostic marker of increased risk of relapse and shorter survival in patients with acute myeloid leukemia (AML) ...
Burden of acute respiratory disease of epidemic and pandemic potential in the WHO Eastern Mediterranean Region: A literature ... Burden of acute respiratory disease of epidemic and pandemic potential in the WHO Eastern Mediterranean Region: a literature ... 1991). Diarrhoeal and acute respiratory disease : the current situation. Geneva : World Health Organization. http://www.who. ... There are gaps in the knowledge about the burden of severe respiratory disease in the Eastern Mediterranean Region [EMR]. ...
... typical acute retroviral syndrome disease progression, with a wealth of fact sheets, expert advice, community perspective, the ... What Is Acute HIV Infection? Testing for Acute HIV Infection Risk of Immune Damage Risk of Infecting Others Treating Acute HIV ... Acute HIV infection or Disease progression?. Dr. Holodniy,My last negative HIV test was May of 1999. In November and December I ... Question regarding acute retroviral syndrome. To the person who wrote about acute HIV and possible infection with new and ...
Div of Viral Diseases, National Center for Immunization and Respiratory Diseases; Div of Healthcare Quality Promotion, National ... Epidemiology of acute, respiratory disease in military recruits. Am Rev Respir Dis 1968;97(Suppl):1--65. ... Van der Veen J, Kok G. Isolation and typing of adenoviruses recovered from military recruits with acute respiratory disease in ... Ad14 infection was described initially in 1955 (5) and was associated with epidemic acute respiratory disease in military ...
Comprehensive molecular panel for the diagnosis of various tick-borne diseases provides a solution for physicians in that such ... Comprehensive molecular panel for the diagnosis of various tick-borne diseases provides a solution for physicians in that such ... Lyme Disease (Borrelia spp) DNA, Qualitative, Real-Time PCR, Blood ...
Coronary artery disease. I. Management of the acute episode. Br Med J 1971; 1 :93 ... Coronary artery disease. I. Management of the acute episode.. Br Med J 1971; 1 doi: https://doi.org/10.1136/bmj.1.5740.93 ( ...
... M. S. Ahmed,1,2 A. B. Jadhav,1,2 A. Hassan,1 and Qing H. ... and cardiovascular disease in patients with chronic kidney disease," American Journal of Kidney Diseases, vol. 42, no. 1, pp. ... R. H. Falk and S. W. Dubrey, "Amyloid heart disease," Progress in Cardiovascular Diseases, vol. 52, no. 4, pp. 347-361, 2010. ... I. Kushner, M. L. Broder, and D. Karp, "Control of the acute phase response. Serum C-reactive protein kinetics after acute ...
Dammin, G. J. (1964). The pathogenesis of acute diarrhoeal disease in early life*. Bulletin of the World Health Organization ...
Treatment of Acute Canine Kidney Disease. Treatment of acute kidney disease in dogs includes administering fluids under the ... and progression of acute kidney disease. Symptoms of Chronic Canine Kidney Disease. Symptoms of chronic renal disease may not ... Chronic Canine Kidney Disease. Chronic canine kidney disease differs from the acute form in that the loss of kidney function ... Acute canine kidney disease is the sudden interruption of kidney function without time for adaptive mechanisms to begin. There ...
ACUTE DIARRHOEAL DISEASES: ACUTE DIARRHOEAL DISEASES DR.SUDHARSHINI. DIARRHOEA: DIARRHOEA DEFINITION The passage of loose , ... Leading Causes of Mortality and Burden of Disease world, 2004 % Ischaemic heart disease 12.2 Cerebrovascular disease 9.7 Lower ... Chrons disease Acute diarrhoea lasts a few days or up to a week X IMPORTANT !!! distinguish between acute and chronic ... ACUTE DIARRHOEA WITH SEVERE DEHYDRATION (Plan - C) : ACUTE DIARRHOEA WITH SEVERE DEHYDRATION (Plan - C) Rapid bolus of Ringer ...
Management of Acute Coronary Syndromes is the most up to date and comprehensive evidence-based guide to managing acute coronary ... Chapter 7 Post-hospitalization care of patients with acute coronary syndrome 173. Jersey Chen and Eli V. Gelfand ... Chapter 1 Pathophysiology of acute coronary syndromes 1. Alisa B. Rosen and Eli V. Gelfand ... Chapter 2 Diagnosis of acute coronary syndrome 13. Eli V. Gelfand and Alisa B. Rosen ...
Care guide for Acute Graft Versus Host Disease. Includes: possible causes, signs and symptoms, standard treatment options and ... They can spread disease and cause you to get an infection.. *Wear a mask as directed. You may need to wear a mask when you ... Acute GVHD happens in the first 100 days after your transplant.. What increases my risk for GVHD?. *Older age of you or the ... What are the signs and symptoms of acute GVHD?. Symptoms may be mild to severe. You may have any of the following:. *A skin ...
Graft-versus-GvHDChronic obstrucMyeloid leukemiaCases of acuteSyndromeCoronaryLiverRenal diseaseAGVHDCardiovascularPathogenesisInfectiousSymptoms of acuteTreatmentKidneyMyelogenous leukemiaRheumatic feverIntermittent PorphyriaInflammatoryCrohn's DiseaseCommunicable Disease2017ExacerbationsConclusionsDifferential diagnosis of acuteViralOutcomes2016Vasculitis of unknownHealthcareCenters for DiseasIncidenceMeningococcal diseaseAssociation with acuteMeSHOutbreakHepaticClinical trials
- 1. Management of acute graft-versus-host disease Andrea Bacigalupo Divisione Ematologia e Trapianto di Midollo, Ospedale San Martino, Genova, Italy Summary Acute graft-versus-host disease (GvHD) is a frequent compli- cation of allogeneic haemopoietic stem cell transplantation (HSCT) and donor lymphocyte infusions (DLI). (slideshare.net)
- Keywords: graft-versus-host disease, haemopoietic stem cell transplantation, donor lymphocyte infusion, immunosuppres- sive therapy, mesenchymal stem cells. (slideshare.net)
- Although the pathogenesis of graft-versus-host disease (GvHD) is not the aim of the present review, a few words are warranted: indeed some of the recent advances in understanding cellular and cytokine mechanisms leading to GvHD have been useful in the clinic. (slideshare.net)
- What is graft versus host disease (GVHD)? (drugs.com)
- Graft-versus-Host disease (GVHD) often occurs after allogeneic bone marrow transplants (BMT). (nationwidechildrens.org)
- RATIONALE: Mycophenolate mofetil added to immunosuppressive treatment regimens may be effective in treating newly diagnosed chronic graft-versus-host disease caused by stem cell transplant. (bioportfolio.com)
- RATIONALE: Giving different schedules of mycophenolate mofetil and cyclosporine may be effective in reducing graft-versus-host disease in patients undergoing donor peripheral stem cell tra. (bioportfolio.com)
- This pilot phase II trial studies how well high dose cyclophosphamide, tacrolimus, and mycophenolate mofetil work in preventing graft versus host disease in patients with hematological mal. (bioportfolio.com)
- Comparative analysis of calcineurin-inhibitor-based methotrexate and mycophenolate mofetil-containing regimens for prevention of Graft-versus-Host Disease after reduced intensity conditioning allogeneic transplantation. (bioportfolio.com)
- A pediatric case of squamous cell cancer in situ in the setting of sclerodermatous graft-versus-host disease and voriconazole treatment. (bioportfolio.com)
- Upper gastrointestinal acute graft-versus-host disease adds minimal prognostic value in isolation or with other graft-versus-host disease symptoms as currently diagnosed and treated. (bioportfolio.com)
- Upper gastrointestinal acute graft-versus-host disease is reported in approximately 30% of hematopoietic stem cell transplant recipients developing acute graft-versus-host disease. (bioportfolio.com)
- Major drivers for this transaction were Mesoblast's evaluation of the use of Prochymal® for inflammatory diseases of the bowel, including patients with Crohn's Disease who have failed other biologic agents and patients with potentially life-threatening Graft Versus Host Disease (GVHD) involving the gut and liver after a bone marrow transplant. (cnbc.com)
- Acute graft-versus-host disease (aGVHD) is the most common complication for patients undergoing allogeneic stem cell transplantation. (jci.org)
- Acute graft-versus-host disease (aCGVHD) is common after a transplant with donor cells. (bmtinfonet.org)
- A study of itacitinib or placebo in combination with corticosteroids for treatment of acute graft-versus-host disease. (rush.edu)
- A common side effect of allo-HSCTs is graft-versus-host disease (GVHD). (rush.edu)
- Acute graft-versus-host disease (aGvHD) is the most frequent and serious complication following hematopoietic stem cell transplantation (HSCT), with a high mortality rate. (frontiersin.org)
- However, up to 40% of HSCT patients will develop graft-versus-host disease (GvHD) in either an acute or a chronic form ( 2 ). (frontiersin.org)
- This study will explore the role of a bacterial toxin (endotoxin), which normally resides in the intestine but enters the bloodstream as a consequence of chemo- and radio-therapy in patients with leukemia or lymphoma undergoing bone marrow transplantation, in initiating Graft-versus-Host Disease (GVHD) in transplant recipients. (dana.org)
- However, HSCT is frequently complicated by acute graft-versus-host disease (aGVHD) wherein donor T lymphocytes target recipient tissue antigens. (dana.org)
- First-line treatment of acute GvHD is based on corticosteroids, and produce sustained responses in 50-80% of patients depending on the initial severity. (slideshare.net)
- Acute GvHD is complicated by severe immunodefi- ciency causing life-threatening infections. (slideshare.net)
- Acute GVHD happens in the first 100 days after your transplant. (drugs.com)
- What are the signs and symptoms of acute GVHD? (drugs.com)
- GVHD can be a minor, short-term problem or a serious, life-threatening disease. (nationwidechildrens.org)
- There are two types of GVHD: Chronic and Acute. (nationwidechildrens.org)
- Acute GVHD most often occurs in the first 100 days after a bone marrow transplant. (nationwidechildrens.org)
- Jaundice (yellow skin and eyes) can mean Acute GVHD has affected the liver. (nationwidechildrens.org)
- Acute GVHD may be mild, moderate, severe or life-threatening (see chart). (nationwidechildrens.org)
- To reduce the risk of acute GVHD, BMT patients are given special drugs before and after a transplant. (nationwidechildrens.org)
- Phase III , randomized double blind, placebo controlled, and trial evaluating the addition of MMF vs. placebo to systemic corticosteroids as initial therapy for acute GVHD. (bioportfolio.com)
- Corticosteroids have been used as primary therapy for acute GVHD for many years. (bioportfolio.com)
- corticosteroid therapy for previously untreated patients with acute GVHD. (bioportfolio.com)
- This trial will test the hypothesis that the combination of sirolimus and mycophenolate mofetil will be effective in preventing both acute and chronic GVHD after reduced intensity allogene. (bioportfolio.com)
- Mesoblast will meet with the United States Food and Drug Administration (FDA) shortly to discuss potential pathways for accelerated Prochymal® product approvals in the United States for the treatment of steroid-refractory acute GVHD, a disease with inflammatory etiology and a significant gastrointestinal component. (cnbc.com)
- Approximately 30-40 percent of patients who are transplanted with cells from a related donor develop acute GVHD. (bmtinfonet.org)
- Acute GVHD typically occurs during the first three months after transplant, although it can also occur later. (bmtinfonet.org)
- The risk of developing acute GVHD is highest in patients who were transplanted with a mismatched or unrelated donor. (bmtinfonet.org)
- In most patients, acute GVHD first affects the skin. (bmtinfonet.org)
- Tell your doctor immediately if you develop a skin rash or other symptoms of acute GVHD. (bmtinfonet.org)
- Although these symptoms may be caused by other health problems, early detection and treatment of acute GVHD is important to prevent other, serious complications. (bmtinfonet.org)
- If you develop acute GVHD, drugs such as prednisone or methylprednisolone may help control the disease. (bmtinfonet.org)
- Your doctor may also recommend that you enroll in a clinical trial that is testing a new therapy for acute GVHD. (bmtinfonet.org)
- It's important to continue taking your medications for acute GVHD, even if you are feeling better. (bmtinfonet.org)
- Rare causes of acute GVHD include maternal transfer of lymphocytes via the placenta to an immunodeficient infant, and transfusion of non-irradiated blood to a patient whose immune system cannot reject the donor lymphocytes, either due to immunodeficiency, histocompatibility, or transient immunocompromise from large volume transfusion or bypass. (renalandurologynews.com)
- Outside of these rare settings, acute GVHD is typically only seen in the context of allogeneic BMT (bone marrow transplantation). (renalandurologynews.com)
- Several studies have shown that peripheral blood stem cells carry greater risk for acute GVHD than bone marrow, but this finding is still controversial. (renalandurologynews.com)
- Children are at lower risk of developing acute GVHD than adults. (renalandurologynews.com)
- Older donor age has been associated with increased risk of acute GVHD. (renalandurologynews.com)
- Female donors increase the risk of acute GVHD in male recipients. (renalandurologynews.com)
- Reduced or non-myeloablative transplants reduce the incidence, and delay the onset of acute GVHD. (renalandurologynews.com)
- Ex vivo T-cell depletion or in vivo administration of anti-T-cell antibody therapies around the time of donor graft infusion (such as antithymocyte globulin or alemtuzumab) decreases the risk of acute GVHD. (renalandurologynews.com)
- Acute GVHD is staged on a scale of 0 to IV based on a composite score derived from each of the three target organs (skin, liver, GI [gastrointestinal] tract). (renalandurologynews.com)
- Although acute GVHD can develop at any time following allogeneic BMT, the clinical symptoms typically develop between 3 to 4 weeks after the transplant in one of the classic target organs - the skin, liver or GI tract. (renalandurologynews.com)
- Acute GVHD is a clinical diagnosis. (renalandurologynews.com)
- Acute GVHD biomarkers in the plasma may become useful for diagnostic and prognostic purposes in the next few years, but at present they are only used in research settings. (renalandurologynews.com)
- Acute GvHD (aGvHD) is a serious complication of HSCT and occurs when T cells in the graft elicit an immune response against the host, causing tissue damage in the skin, liver, and gastrointestinal tract ( 2 ). (frontiersin.org)
- They will use complementary areas of expertise, including oncology/hematology (Dana-Farber), infectious diseases (Children's Hospital Boston), and microbiology (University of Iowa), to examine how GVHD is initiated in bone marrow transplant recipients. (dana.org)
- I. Evaluate the effect of brentuximab vedotin on the clinical manifestations of acute GVHD of the liver and gastrointestinal tract. (clinicaltrials.gov)
- books.google.com - This unique, single-source volume--the only comprehensive, first-line reference available on the subject-provides in-depth, up-to-date reviews of both the clinical and pathophysiological aspects of acute respiratory failure (ARF) in chronic obstructive pulmonary disease (COPD). (google.com)
- Acute exacerbations of chronic obstructive pulmonary disease (COPD) are a frequent cause of hospitalization in the United States. (nih.gov)
- I read the position paper on acute exacerbations of chronic obstructive pulmonary disease (COPD) with great interest (1, 2) . (annals.org)
- Evaluating measurable residual disease in acute myeloid leukemia. (nih.gov)
- Mounting evidence indicates that the presence of measurable ("minimal") residual disease (MRD), defined as posttherapy persistence of leukemic cells at levels below morphologic detection, is a strong, independent prognostic marker of increased risk of relapse and shorter survival in patients with acute myeloid leukemia (AML) and can be used to refine risk-stratification and treatment response assessment. (nih.gov)
- Tamoxifen therapy has been associated with the development of acute myeloid leukemia during breast cancer treatment. (greenmedinfo.com)
- Objective: The mouse Shb gene coding for the Src Homology 2-domain containing adapter protein B has recently been placed in context of BCRABL1 -induced myeloid leukemia in mice and the current study was performed in order to relate SHB to human acute myeloid leukemia (AML). (diva-portal.org)
- Minimal Residual Disease in Acute Myeloid Leukemia: Still a Work in Progress? (mdpi.com)
- As such, its application in acute myeloid leukemia has greatly increased our ability to quantify treatment response, and to determine the chemosensitivity of the disease, as the final product of the drug schedule, dose intensity, biodistribution, and the pharmakogenetic profile of the patient. (mdpi.com)
- There is now consistent evidence for the prognostic power of minimal residual disease evaluation in acute myeloid leukemia, which is complementary to the baseline prognostic assessment of the disease. (mdpi.com)
- In this review, we will summarize the results of the major clinical studies evaluating minimal residual disease in acute myeloid leukemia in adults in recent years and address the technical and practical issues still hampering the spread of these techniques outside controlled clinical trials. (mdpi.com)
- Still, as final standardization and diffusion of the methods are sorted out, we believe that minimal residual disease will soon become the new standard for evaluating response in the treatment of acute myeloid leukemia. (mdpi.com)
- During the same period, there were 43,580 cases of acute pancreatitis in the overall population, including 226 cases (0.5%) among methimazole users and 19 cases (0.04%) among PTU users, with a case-crossover analysis showing an odds ratio (OR) of 1.51 (95% CI, 1.12 - 2.02) for acute pancreatitis among methimazole users and an OR of 1.16 (95% CI, 0.46 - 2.93) among PTU users, respectively. (medscape.com)
- The CDC has been investigating hundreds of possible cases of acute flaccid myelitis in multiple states. (usatoday.com)
- The CDC has been investigating at least 386 possible cases of acute flaccid myelitis dating to 2014 and recently confirmed 62 cases in 22 states this year. (usatoday.com)
- Since the early 1960s, a number of publications reported cases of acute oliguric kidney insufficiency complicating the course of MCD in adults. (springer.com)
- All cases of acute meningococcal disease should be managed in a facility with the capacity to provide paediatric intensive care. (rch.org.au)
- Familial histories of autoimmune disease in first- and second-degree relatives were compared in 279 incident cases, 240 cases of acute lymphocytic leukemia (ALL) and 39 cases of acute non-lymphoblastic leukemia (ANLL), and 285 controls. (aacrjournals.org)
- Finally, a total of 279 incident cases of acute leukemia confirmed by cytology and 285 controls were included in the study. (aacrjournals.org)
- Because of the recent increases in the number of cases of acute Chagas disease in the Amazon region, it is important to consider this disease in the differential diagnosis of acute febrile neurological syndromes in this region. (scielo.br)
- Most cases of acute kidney injury occur in people who are already in the hospital for other reasons. (lmh.org)
- There is no perfect, all-encompassing answer to what acute retroviral syndrome may consist of. (thebody.com)
- If your dates are correct, it sounds like acute retroviral syndrome . (thebody.com)
- Dear Dr. Gallant, If a person infected with HIV experiences acute retroviral syndrome, does that mean that s/he is in theprocess of seroconverting? (thebody.com)
- Yes, someone with the acute retroviral syndrome is in the process of seroconverting. (thebody.com)
- actually sounds more like you experienced a predictable rebound in your viral load after stopping your medications leading to an acute retroviral syndrome . (thebody.com)
- Autopsy and histologic findings at the Office of the Chief Medical Examiner in New York City included presence in the lung of chronic inflammatory cells with intranuclear inclusions, consistent with adenoviral bronchiolitis and acute respiratory distress syndrome. (cdc.gov)
- Elevated C-reactive protein in acute coronary syndrome presentation is an independent predictor of long-term mortality and heart failure," Clinical Biochemistry , vol. 40, no. 5-6, pp. 326-329, 2007. (hindawi.com)
- Inflammation and long-term mortality after non-ST elevation acute coronary syndrome treated with a very early invasive strategy in 1042 consecutive patients," Circulation , vol. 105, no. 12, pp. 1412-1415, 2002. (hindawi.com)
- Outcomes should include pain and adverse events such as acute chest syndrome. (nice.org.uk)
- Lowered protein content of tissue fluid in patients with the nephrotic syndrome: observations during disease and recovery. (springer.com)
- Hypersensitivity pneumonitis and acute respiratory distress syndrome from e-cigarette use. (greenmedinfo.com)
- Overtesting for Acute Coronary Syndrome(ACS) and Pulmonary Embolism (PE) in low risk Emergency Department(ED) patients can increase exposure of nondiseased patients to radiation, intravenous contrast and anticoagulation. (clinicaltrials.gov)
- The liver diseases unique to pregnancy include hyperemesis gravidarum, acute fatty liver of pregnancy (AFLP), intrahepatic cholestasis of pregnancy (ICP), and hemolysis and elevated liver enzymes and low platelets (HELLP) syndrome. (medscape.com)
- Acute transverse myelitis (ATM) is a rare, potentially devastating neurological syndrome that has variety of causes, infectious being one of them. (prohealth.com)
- Acute chest syndrome is a lung-related complication of sickle cell disease that can lower the levels of oxygen in the blood and can be life-threatening. (adventisthealthcare.com)
- Repeat occurrences of acute chest syndrome can cause lung damage. (adventisthealthcare.com)
- Because a person with acute chest syndrome can deteriorate rapidly, a hospital stay is usually needed. (adventisthealthcare.com)
- Monitoring the amount of fluids being consumed, because fluids may build up in the lungs ( pulmonary edema ) during acute chest syndrome. (adventisthealthcare.com)
- Methods and Results- The Get With the Guidelines-Coronary Artery Disease database was queried to determine whether compliance with quality-of-care treatments for acute coronary syndrome patients was associated with the extent of prior vascular disease. (ahajournals.org)
- Conclusions- Compared with acute coronary syndrome patients without prior vascular disease, those with prior atherosclerosis had higher in-hospital mortality yet were paradoxically less likely to receive specific evidence-based acute coronary syndrome treatments, which can form the basis for targeted intervention. (ahajournals.org)
- 1,2 Patients with acute coronary syndrome (ACS) and known prior vascular disease have a high risk of early and late complications, 3-8 especially if they have atherosclerosis in more than 1 vascular bed, 7 and may derive significant benefit from aggressive evidence-based treatment. (ahajournals.org)
- By mid-February 2003, Chinese health officials tracked more than 300 cases, including five deaths in Guangdong province from what was at the time described as an acute respiratory syndrome. (jrank.org)
- Unaware of the problems in China, Urbani's report drew increased attention among epidemiologists when coupled with news reports in mid-March that Hong Kong health officials had also discovered an outbreak of an acute respiratory syndrome among health care workers. (jrank.org)
- A 16-year-old female patient from Tefé (State of Amazonas) started with acute febrile syndrome on May 15, 2004. (scielo.br)
- What is acute chest syndrome? (stjude.org)
- Acute chest syndrome (ACS) is a complication (health problem) caused by sickle cell disease. (stjude.org)
- Can my child get acute chest syndrome more than one time? (stjude.org)
- Viral illnesses can progress to acute chest syndrome. (stjude.org)
- Acute Coronary Syndrome - Ischemic Heart Disease. (arupconsult.com)
- Though hepatorenal syndrome (HRS) is thought to be the most common entity in any kidney affection which takes place in patients with liver disease, it in fact is the least common amongst all causes of AKI in this patient population. (springer.com)
- Hepatorenal syndrome: the 8th international consensus conference of the Acute Dialysis Quality Initiative (ADQI) Group. (springer.com)
- Acute esophageal necrosis (AEN), also known as Gurvits syndrome, black esophagus, acute necrotizing esophagitis, and esophageal infarction is a rare esophageal disorder. (wikipedia.org)
- Advanced age (average patient aged 57 years old) Male sex (4 to 1 male dominance) Cirrhosis AIDS Herpes virus Atrial fibrilation Diabetes (currently the most prevalent out of all conditions in patients) Aortic dissection Anti-cardiolipin antibodies CMV infection Herpetic infection Hyperglycemia Hypersensitivity to broad-spectrum antibiotics Hypothermia Ischemia Gastric volvulus Posterior mediastinal haematoma Septic shock Steven Johnson syndrome Acute esophageal necrosis can only be diagnosed by an upper gastrointestinal endoscopy. (wikipedia.org)
- Frequency and predictors of urgent coronary angiography in patients with acute pericarditis. (medscape.com)
- books.google.com - One of the leading experts in the field and a stellar cast of contributors provide all of the scientific and clinical information needed to facilitate rapid evaluation and immediate management of acute coronary syndromes using today's full range of strategies-from pharmaceutical approaches to revascularization. (google.com)
- Coronary artery disease. (bmj.com)
- Pentecost B L . Coronary artery disease. (bmj.com)
- C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (monitoring trends and determinants in cardiovascular disease) Augsburg cohort study, 1984 to 1992," Circulation , vol. 99, no. 2, pp. 237-242, 1999. (hindawi.com)
- Serum amyloid A is a better predictor of clinical outcomes than C-reactive protein in non-ST-segment elevation acute coronary syndromes," Circulation Journal , vol. 71, no. 2, pp. 186-190, 2007. (hindawi.com)
- Management of Acute Coronary Syndromes is designed to provide busy clinicians with a comprehensive guide to the investigation, diagnosis and treatment of these syndromes. (wiley.com)
- Management of Acute Coronary Syndromes is the most up to date and comprehensive evidence-based guide to managing acute coronary syndromes, in a compact and usable format. (wiley.com)
- Although patients with chronic kidney disease were less likely to receive effective cardiac medications or undergo coronary interventional procedures than patients without kidney disease, we observed a marked increase in the use of effective cardiac medications and coronary interventional procedures in patients with chronic kidney disease during the period under study. (nih.gov)
- Thought you might appreciate this item(s) I saw at Coronary Artery Disease. (lww.com)
- 1 , 2 Although intravenous immunoglobulin (IVIG) has been shown to reduce both the duration of fever and the incidence of coronary artery abnormalities (CAAs) with the use of 2 g/kg in a single dose, 3 , 4 the role and appropriate dose of aspirin during the acute phase is still unclear. (aappublications.org)
- Background- Patients with prior atherosclerosis in 1 or more vascular territories (coronary, cerebrovascular, or peripheral arterial) who present with acute coronary syndromes have high cardiovascular risk and may benefit significantly from evidence-based therapies, yet whether these are used consistently is unknown. (ahajournals.org)
- The American Heart Association Get With The Guidelines-Coronary Artery Disease (GWTG-CAD) Program has been collecting a large amount of information on the in-hospital management of ACS patient since 2000 and offers a unique opportunity to examine patterns of in-hospital ACS treatment. (ahajournals.org)
- The GWTG is a registry and performance-improvement initiative undertaken by the American Heart Association to enhance guideline adherence among hospitalized patients with coronary artery disease (CAD). (ahajournals.org)
- Liver disease that occurs during pregnancy can present a challenge for healthcare providers. (medscape.com)
- Certain liver diseases are uniquely associated with pregnancy, whereas others are unrelated. (medscape.com)
- [ 1 ] Liver disease such as acute viral hepatitis can occur in pregnancy, and pregnancy may occur in a patient with underlying chronic liver disease, including patients with cirrhosis and portal hypertension, and patients who have undergone liver transplantation. (medscape.com)
- Ultrasonography is safe and the preferred imaging modality for the assessment of abnormal liver studies suggestive of biliary tract disease. (medscape.com)
- Pregnancy-related diseases are the most frequent causes of liver dysfunction during pregnancy and exhibit a trimester-specific occurrence during pregnancy. (medscape.com)
- Antioxidative status of patients with alcoholic liver disease in southeastern Taiwan. (biomedsearch.com)
- Acute liver failure is a rare, serious condition. (childliverdisease.org)
- Acute liver failure is when liver cells suddenly die or stop functioning normally. (childliverdisease.org)
- In the past acute liver failure has been called fulminant liver failure. (childliverdisease.org)
- What can cause acute liver failure? (childliverdisease.org)
- Your child will be transferred from a local hospital to a specialist centre so they can be looked after by a team who have more experience looking after children with acute liver failure. (childliverdisease.org)
- What are the complications of acute liver failure? (childliverdisease.org)
- Acute liver failure makes it more likely for a child to get an infection. (childliverdisease.org)
- Liver disease follows a fairly predictable course. (petwave.com)
- Causes & Prevention of Liver Disease in Dogs: Veterinarian reviewed information that explains the causes of dog Liver Disease, including how it may be prevented. (petwave.com)
- How Liver Disease in dogs is diagnosed: Underlying conditions associated with Liver Disease may create complications, so your veterinarian is always the best resource to successfully diagnose this condition. (petwave.com)
- Identifying the symptoms and signs of Liver Disease in dogs is the first step to knowing if your dog requires medical attention. (petwave.com)
- Treating Liver Disease in Dogs: Veterinarian reviewed information on the treatment options for dog Liver Disease. (petwave.com)
- However, AKI in the setting of liver disease has not been extensively studied. (springer.com)
- The peculiarities of liver disease, especially the fact that the usual criteria of diagnosing AKI in patients with non-liver disease (urine output and serum creatinine) cannot be accurately assessed in patients with liver disease, impedes diagnosis and follow up of kidney injury. (springer.com)
- Incidence, aetiology, pathogenesis and management of AKI will depend on the liver disease in question-acute liver failure, decompensated liver disease, acute-on-chronic liver failure or post liver transplantation. (springer.com)
- Therefore, AKI in liver disease can be a challenging entity for the treating clinician, right from diagnosing its aetiology to the management. (springer.com)
- In this chapter, we explore the existing pathophysiological basis, treatment modalities and controversies in the diagnosis and treatment of AKI in paediatric patients with liver disease and discuss our own personal practice in this condition. (springer.com)
- Factors related to post-liver transplantation acute renal failure. (springer.com)
- Risk factors and outcomes of acute kidney injury in patients with acute liver failure. (springer.com)
- Model for end-stage liver disease score and systemic inflammatory response are major prognostic factors in patients with cirrhosis and acute functional renal failure. (springer.com)
- Moore K. Renal failure in acute liver failure. (springer.com)
- Slack A, Yeoman A, Wendon J. Renal dysfunction in chronic liver disease. (springer.com)
- Inaccuracies of creatinine and creatinine-based equations in candidates for liver transplantation with low creatinine: impact on the model for end-stage liver disease score. (springer.com)
- The aim of this proposal is to examine the role of inflammatory signalling pathways in murine models of liver and biliary disease by application of conditional gene targeting using cre/loxP technology. (europa.eu)
- In the second part of this proposal, we will extend these studies by evaluating the function of NEMO/NF-kB in other hepatic cell compartments, specifically the function of NEMO in hepatic stellate cells and liver fibrosis, the endothelial function of NEMO/NF-kB in an in vivo model of hepatic ischemia-reperfusion injury and the role of the NF-kB pathway in biliary epithelial cells and inflammatory biliary diseases. (europa.eu)
- Finally, in the third part of this proposal we will analyse the unknown intrahepatic role of non-canonical, IKK1-dependent signalling pathways and the function of TAK1 - a molecule at the interface between inflammatory and developmental pathways - in liver injury, fatty-liver-disease and insulin-resistance. (europa.eu)
- Knowledge gained by these studies and the further understanding of the cell specific hepatic function of NF-kB and related pathways might build the basis for the development of novel pharmacological approaches for the future treatment of liver diseases and cancer in humans. (europa.eu)
- AHP is comprised of four subtypes, each resulting from a genetic defect leading to deficiency in one of the enzymes of the heme biosynthesis pathway in the liver: acute intermittent porphyria (AIP), hereditary coproporphyria (HCP), variegate porphyria (VP), and ALAD-deficiency porphyria (ADP). (businesswire.com)
- In addition, long-term complications of AHP and its treatment can include chronic neuropathic pain, hypertension, chronic kidney disease and liver disease, including iron overload, fibrosis, cirrhosis and hepatocellular carcinoma. (businesswire.com)
- Once symptoms are present, they are very similar to those of acute renal disease. (vetinfo.com)
- Infusion of donor ILC2s was effective in reducing the lethality of aGVHD and in treating lower GI tract disease. (jci.org)
- Selected microRNAs ( n = 10) were replicated in independent cohorts of serum samples taken at aGvHD diagnosis ( n = 42) and prior to disease onset (day 14 post-HSCT, n = 47) to assess their prognostic potential. (frontiersin.org)
- Effects of statins on nonlipid serum markers associated with cardiovascular disease: a systematic review," Annals of Internal Medicine , vol. 139, no. 8, pp. 670-682, 2003. (hindawi.com)
- Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the centers for disease control and prevention and the American Heart Association," Circulation , vol. 107, no. 3, pp. 499-511, 2003. (hindawi.com)
- Advance knowledge in biomarkers of acute cardiovascular disease through research and education, including the preanalytical, analytical, and post-analytical phases of testing. (aacc.org)
- Establish an international forum with a focus on laboratory medicine for laboratory professionals, physicians, individuals in industry, regulatory agencies and other stakeholders with an interest in biomarkers of acute cardiovascular diseases. (aacc.org)
- Establish a mechanism for young clinical laboratory professionals to gain clinical, research and development, and interpretive experience in the area of biomarkers of acute cardiovascular disease. (aacc.org)
- Toe brachial index predicts major acute cardiovascular events in patients with type 2 diabetes independently of arterial stiffness. (harvard.edu)
- It has been seen that periodontal disease can affect the course and pathogenesis of a number of systemic diseases such as cardiovascular disease, diabetes mellitus and cerebrovascular stroke. (omicsonline.org)
- Guilherme L, Ramasawmy R, Kalil J. Rheumatic fever and rheumatic heart disease: genetics and pathogenesis. (freemd.com)
- These inflammatory pathways are central to the pathogenesis of Crohn's Disease and inflammatory bowel diseases. (cnbc.com)
- Infectious and noninfectious acute pericarditis in children: an 11-year experience. (medscape.com)
- To prevent and control infectious disease (excluding TB , STD , and HIV/AIDS ) in Los Angeles County by implementing tools for surveillance, outbreak response, education, and preparedness activities. (lacounty.gov)
- The Pediatric Infectious Disease Journal22(10):874-878, October 2003. (lww.com)
- The association between a familial history of autoimmune disease and childhood acute leukemia was investigated in a French case-control study that, overall, was designed to assess the role of perinatal, infectious, environmental, and genetic factors in the etiology of childhood acute leukemia. (aacrjournals.org)
- SARS cases provided a test of recent reforms in International Health Regulations designed to increase surveillance and reporting of infectious diseases-and to enhance cooperation in preventing the international spread of disease. (jrank.org)
- Emerging Infectious Diseases , 9 (9), 1183-1184. (cdc.gov)
- Rapid isolation of the adult patients contributed to reduced frequency of exposure for children in that household, which is in contrast to the usual infectious diseases of childhood (since children do not have immunity against many age-old microbes). (cdc.gov)
- The most classic sign of AEN is the dark pigmentation of esophageal mucosa in an upper endoscopy, usually viewed as an ulcer or as an infectious disease. (wikipedia.org)
- Transplant Infectious Disease. (wikipedia.org)
- Here, we discuss the symptoms of acute vs chronic Lyme disease and how to get the help you need. (mindbodygreen.com)
- CHICAGO - The treatment of Graves disease with the antithyroid drug methimazole is associated with a significantly increased risk of acute pancreatitis, and although cases are rare, the risk justifies warnings about this potential adverse event, according to a nationwide controlled study in Denmark spanning more than 20 years. (medscape.com)
- Treatment of acute kidney disease in dogs includes administering fluids under the skin or by IV, diuretics to enhance urine output, medications to enhance blood flow to the kidneys and to control blood pressure, control of vomiting and diarrhea, and proper nutrition with high fat, high carbohydrate, and decreased protein diet. (vetinfo.com)
- Treatment of chronic canine kidney disease is aimed at controlling the symptoms of the disease and slowing the progression of the illness. (vetinfo.com)
- Why this is important:- Limited evidence is available on the effectiveness of different opioid formulations, routes of administration and adjunct therapies in the treatment of an acute painful sickle cell episode. (nice.org.uk)
- Supplementation with molasses may have therapeutic value in the treatment of acute myelogeneous leukemia. (greenmedinfo.com)
- Guidelines for treatment of acute lung diseases. (wikipedia.org)
- To evaluate the effect of treatment without aspirin in the acute phase of Kawasaki disease (KD) and to determine whether it is necessary to expose children to high- or medium-dose aspirin. (aappublications.org)
- The results of our study indicate that the treatment without aspirin in acute stage of KD had no effect on the response rate of IVIG therapy, duration of fever, or incidence of CAAs when children were treated with high-dose (2 g/kg) IVIG as a single infusion, despite treatment before or after day 5 of illness. (aappublications.org)
- 7 The purpose of this study was to evaluate the effect of treatment without aspirin in acute KD from 10 years' experience in a single medical center, and we discuss the need for adding aspirin to the initial treatment of acute KD. (aappublications.org)
- Further research into leukaemia, and indeed other cancers, will allow researchers to understand the patterns of how the disease develops and how patients are going to respond to treatment. (medicalnewstoday.com)
- A recently-completed internal review of the Crohn's Disease program reinforced Mesoblast's intention to complete the ongoing Phase 3 trial in adult patients with Crohn's Disease refractory to treatment with steroids, classic immunosuppressives and biologic therapy. (cnbc.com)
- Baiocco PJ, Korelitz B. The influence of inflammatory bowel disease and its treatment on pregnancy and fetal outcome. (springer.com)
- Over 40,000 hematopoietic stem cell transplants (HSCTs) are carried out in Europe each year ( 1 ) as curative treatment for a range of hematological diseases, including leukemia and lymphoma. (frontiersin.org)
- CAMBRIDGE, Mass.--( BUSINESS WIRE )-- Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY), the leading RNAi therapeutics company and Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD), a GI healthcare company, announced today a U.S. GI disease education and promotional agreement for Alnylam's givosiran, an investigational RNAi therapeutic targeting aminolevulinic acid synthase 1 (ALAS1) for the potential treatment of AHP. (businesswire.com)
- Nearly all patients living with AHP consult at least one, if not several, gastroenterologists due to the recurring abdominal pain associated with their disease and are often misdiagnosed due to minimal disease awareness and a limited number of treatment options," said Barry Greene, President of Alnylam. (businesswire.com)
- Ironwood will collaborate with Alnylam on AHP disease education designed to help ensure AHP patients are accurately diagnosed and to support access to treatment with givosiran once prescribed (assuming approval). (businesswire.com)
- Only treatment is for the underlying main diseases or conditions. (wikipedia.org)
- Acute canine kidney disease is the sudden interruption of kidney function without time for adaptive mechanisms to begin. (vetinfo.com)
- There can be many causes for acute kidney disease including toxic ingestion of food or chemicals (ingestion of antifreeze is a common one), dehydration, obstructions of the urinary tract from dog bladder stones or tumors, canine bladder infection, and by conditions or injuries that result in diminished blood flow to the kidney. (vetinfo.com)
- Chronic canine kidney disease differs from the acute form in that the loss of kidney function happens over weeks to months rather than suddenly. (vetinfo.com)
- With the chronic form of the disease, the kidneys will try to compensate for the damage to the functional cells of the kidney, called nephrons, by enlarging the remaining undamaged nephrons. (vetinfo.com)
- The prognosis for chronic canine kidney disease is poor. (vetinfo.com)
- In-hospital death rates declined over time among patients with chronic kidney disease, whereas these death rates remained unchanged among persons with normal kidney function. (nih.gov)
- To treat kidney failure effectively, it is important to know whether kidney disease has developed suddenly (acute) or over the long term (chronic). (lmh.org)
- Many conditions, diseases, and medicines can create situations that lead to acute and chronic kidney disease. (lmh.org)
- Acute kidney injury, also called acute renal failure, is more commonly reversible than chronic kidney failure. (lmh.org)
- Acute kidney injury (AKI) is usually caused by an event that leads to kidney malfunction, such as dehydration , blood loss from major surgery or injury, or the use of medicines . (lmh.org)
- Chronic kidney disease (CKD) is usually caused by a long-term disease, such as high blood pressure or diabetes , that slowly damages the kidneys and reduces their function over time. (lmh.org)
- The presence or lack of symptoms may help your doctor determine whether acute kidney injury or chronic kidney disease is present. (lmh.org)
- Symptoms of decreased kidney function, such as fluid buildup or electrolyte imbalance , are more likely to develop with acute kidney injury, regardless of how long the kidney has been malfunctioning. (lmh.org)
- Symptoms of chronic kidney disease may not develop until very little kidney function remains. (lmh.org)
- In these people, acute kidney injury is usually diagnosed when routine tests show a sudden increase in creatinine and blood urea nitrogen (BUN) levels. (lmh.org)
- Your doctor will compare these levels to previous tests to find out if kidney disease is acute or chronic. (lmh.org)
- An ultrasound of the kidneys also may help determine whether kidney problems are acute or chronic. (lmh.org)
- Normal-sized kidneys may be present in either condition, but when both kidneys are smaller than normal, chronic kidney disease is usually the problem. (lmh.org)
- Acute kidney injury (AKI) is a potentially lethal condition for which no therapy is available beyond replacement of renal function. (biologists.org)
- Kaddourah A, Basu RK, Bagshaw SM, Goldstein SL, Investigators A. Epidemiology of acute kidney injury in children and young adults. (springer.com)
- Garcia-Tsao G, Parikh CR, Viola A. Acute kidney injury in cirrhosis. (springer.com)
- Crude oil exposure has been linked to acute myelogenous leukemia and multiple myeloma, in part due to benzene. (greenmedinfo.com)
- Offshore workers have a higher risk of acute myelogenous leukemia, probably due to benzene exposure. (greenmedinfo.com)
- Research of Acute Interstitial Pneumonia has been linked to Pancreatitis, Autoimmune Reaction, Autoimmune Diseases, Disorders Of Porphyrin Metabolism, Acute Intermittent Porphyria. (novusbio.com)
- The incidence of inflammatory bowel disease is rising in general population, especially in adolescence and early adulthood, and consequently, it is rising in pregnant population. (springer.com)
- When inflammatory bowel disease during pregnancy is active, an additional problem is the use of immunomodulatory and biologic agents which can influence fetal development. (springer.com)
- Logan R. Inflammatory bowel disease incidence: up, down or unchanged? (springer.com)
- Review article: reproduction in the patient with inflammatory bowel disease. (springer.com)
- HLA disparity determines disease activity through pregnancy in women with inflammatory bowel disease. (springer.com)
- Role of smoking in inflammatory bowel disease: implications for therapy. (springer.com)
- Sorokin J. Pregnancy and inflammatory bowel disease. (springer.com)
- Pregnancy and inflammatory bowel disease in Greece: a prospective study of seven cases in a single hospital setting. (springer.com)
- Pathway analysis associated the candidate microRNAs with hematological and inflammatory disease. (frontiersin.org)
- Acute pancreatitis is an inflammatory condition of the pancreas. (diabetesjournals.org)
- Only few studies have highlighted the importance of inflammatory markers while assessing the association of periodontal disease and cerebrovascular stroke. (omicsonline.org)
- This paper highlights a clinico-biochemical study designed to investigate the role of periodontal disease as a risk factor for acute cerebrovascular stroke by assessing inflammatory markers such as C-reactive protein. (omicsonline.org)
- Patients entering this study had suffered from Crohn's Disease for an average of 14.2 years, and 80% of the patients required prior surgical intervention to treat their Crohn's disease. (cnbc.com)
- Incidence of Crohn's disease in Cardiff over 60 years: 1986-1990 an update. (springer.com)
- Incidence of juvenile-onset Crohn's disease in Scotland. (springer.com)
- The incidence of Crohn's disease in Cardiff over the last 75 years: an update for 1996-2005. (springer.com)
- Munkholm P. Crohn's disease-occurrence, course and prognosis. (springer.com)
- Munkholm P. Pregnancy, fertility, and disease course in patients with Crohn's disease and ulcerative colitis. (springer.com)
- Surgical resections in parous patients with distal ileal and colonic Crohn's disease. (springer.com)
- Multiple blood transfusions reduce the recurrence rate of Crohn's disease. (springer.com)
- Impact of pregnancy on the clinical activity of Crohn's disease. (springer.com)
- Acute pancreatitis complicating Crohn's disease: mere coincidence or causality? (bmj.com)
- This case report supports the concept of an association between acute pancreatitis and Crohn's disease. (bmj.com)
- Learn what the Acute and Communicable Disease Prevention section is doing to promote health equity. (oregon.gov)
- ACDC's mission is to reduce the incidence of communicable disease (other than TB , STDs , and HIV/AIDS ) in Los Angeles County through prevention, surveillance, and outbreak control. (lacounty.gov)
- Acute exacerbation of COPD also known as acute exacerbations of chronic bronchitis (AECB) is a sudden worsening of COPD symptoms (shortness of breath, quantity and color of phlegm) that typically lasts for several days. (wikipedia.org)
- As the lungs tend to be vulnerable organs due to their exposure to harmful particles in the air, several things can cause an acute exacerbation of COPD: Respiratory infection, being responsible for approximately half of COPD exacerbations. (wikipedia.org)
- Common bacterial pathogens of acute exacerbations include Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis. (wikipedia.org)
- Acute Exacerbations of Chronic Bronchitis. (wikipedia.org)
- Acute exacerbations of chronic bronchitis (AECB) Archived 2006-04-06 at the Wayback Machine. (wikipedia.org)
- To evaluate this potential association, the researchers performed a retrospective analysis of 67,898 patients discharged between 2008 and 2013 and confirmed the primary discharge diagnoses as acute exacerbations of respiratory diseases. (healio.com)
- CONCLUSIONS These data suggest that patients with type 2 diabetes may have an increased risk of acute pancreatitis and biliary disease. (diabetesjournals.org)
- Conclusions Obesity is an important risk factor in the development of acute high-altitude disease. (bmj.com)
- Differential diagnosis of acute pericarditis from normal variant early repolarization and left ventricular hypertrophy with early repolarization: an electrocardiographic study. (medscape.com)
- We report rare manifestation of a common disease and emphasize the importance of considering LD in the differential diagnosis of acute transverse myelitis, particularly in residents of endemic areas. (prohealth.com)
- Friman G, Fohlman J. The epidemiology of viral heart disease. (medscape.com)
- Acute Viral Diseases and Immune System Conference aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Acute Viral Diseases and Immune System Conference. (waset.org)
- It also provides a premier interdisciplinary platform for researchers, practitioners, and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields of Acute Viral Diseases and Immune System Conference. (waset.org)
- The combination of surgical embolectomy and endovascular techniques may improve outcomes of patients with acute lower limb ischemia. (springer.com)
- In the present study, the GWTG-CAD database was queried to determine outcomes and compliance with practice guidelines for ACS patients as a function of the presence and extent of prior vascular disease. (ahajournals.org)
- Trends in Capability of Hospitals to Provide Definitive Acute Care for Children: 2008 to 2016. (harvard.edu)
- Kawasaki disease (KD) is an acute vasculitis of unknown aetiology occurring mostly in infants and young children. (mja.com.au)
- Infection prevention and control measures aim to reduce the spread of disease to vulnerable individuals in both the general community and in healthcare facilities. (oregon.gov)
- Under the terms of the agreement, Ironwood will provide AHP disease education to gastroenterologists and other healthcare practitioners that Ironwood currently calls on for LINZESS ® (linaclotide). (businesswire.com)
- Centers for Disease Control and Prevention. (cdc.gov)
- Saving Lives, Protecting People Centers for Disease Control and Prevention. (cdc.gov)
- More cases of a polio-like disease are affecting children, according to the Centers for Disease Control and Prevention. (usatoday.com)
- Currently, the Centers for Disease Control and Prevention (CDC) estimates that 300,000 people contract Lyme disease in the U.S. every year-but many experts believe the true number of cases is much higher and that many people go undiagnosed (due, in part, to ineffective diagnostic tests ). (mindbodygreen.com)
- Incidence rates of disease and 95% CI were calculated per 100,000 person-years of exposure. (diabetesjournals.org)
- IV ceftriaxone / cefotaxime should be given as soon as meningococcal disease is suspected. (rch.org.au)
- The most recognisable presentations of acute meningococcal disease are sepsis with a progressive non-blanching petechial/purpuric rash, and meningitis with or without sepsis and rash. (rch.org.au)
- Meningococcal disease is spread person-to-person by respiratory droplets. (rch.org.au)
- All cases of suspected meningococcal disease in children. (rch.org.au)
- This is the first report of an orthoreovirus in association with acute human respiratory diseases. (pnas.org)
- Acute Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
- 6 In Japan, concern about hepatic toxicity has led to the use of moderate-dose (30-50 mg/kg per day) aspirin as a recommended standard therapy in the acute phase. (aappublications.org)
- A 65-year-old man known to be a chronic alcoholic and to have hepatic cirrhosis presented with an acute onset of altered mental status, seizures, and Parkinson-like movements. (ajnr.org)
- Acute hepatic porphyria (AHP) refers to a family of rare, genetic diseases characterized by potentially life-threatening attacks and for some patients chronic debilitating symptoms that negatively impact daily functioning and quality of life. (businesswire.com)
- Significant progress has been made in recent years in understanding the pathogen- esis of the disease, and some of these advances have been translated into clinical trials. (slideshare.net)
- Our goal was to produce a reliable, responsive instrument to quantify disease burden in children with acute sinusitis for use in clinical trials. (nih.gov)