Acute Coronary Syndrome
Coronary Angiography
Myocardial Infarction
Coronary Artery Disease
Platelet Aggregation Inhibitors
Angioplasty, Balloon, Coronary
Coronary Disease
Ticlopidine
Coronary Thrombosis
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Risk Factors
Treatment Outcome
Platelet Glycoprotein GPIIb-IIIa Complex
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
Troponin T
Coronary Artery Bypass
Prospective Studies
Angina Pectoris
Percutaneous Coronary Intervention
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Myocardial Revascularization
Troponin I
Risk Assessment
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Purinergic P2Y Receptor Antagonists
Prognosis
Aspirin
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Enoxaparin
Follow-Up Studies
Coronary Care Units
Ultrasonography, Interventional
C-Reactive Protein
Troponin
Stents
Angina, Stable
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiovascular Agents
Rupture, Spontaneous
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Registries
Hirudins
Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.
Acetanilides
Coronary Aneurysm
Hospital Mortality
Heparin
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
Coronary Restenosis
Randomized Controlled Trials as Topic
Kaplan-Meier Estimate
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Severity of Illness Index
Multivariate Analysis
Coronary Occlusion
Triage
Hirudin Therapy
Drug Therapy, Combination
Cardiac Catheterization
Double-Blind Method
Chi-Square Distribution
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Creatine Kinase
A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Thrombolytic Therapy
Proportional Hazards Models
Pravastatin
Platelet Activation
Sensitivity and Specificity
Metabolic Syndrome X
A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
Natriuretic Peptide, Brain
Secondary Prevention
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Incidence
Logistic Models
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Vascular Calcification
Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
ROC Curve
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Immunoglobulin Fab Fragments
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
No-Reflow Phenomenon
Emergency Medical Services
Survival Analysis
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Adenosine
Platelet Function Tests
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Odds Ratio
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
Adrenergic beta-Antagonists
Epidemiologic Methods
Death, Sudden, Cardiac
Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
Heparin, Low-Molecular-Weight
Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.
Dalteparin
Tomography, X-Ray Computed
Practice Guidelines as Topic
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
Pregnancy-Associated Plasma Protein-A
A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa.
Myocardial Reperfusion
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
Receptors, Purinergic P2Y12
Cardiovascular Diseases
Emergency Service, Hospital
Cholesterol, LDL
Platelet Aggregation
Down Syndrome
A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
Cardiology Service, Hospital
Phospholipases A2, Secretory
A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes.
Sex Factors
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Regression Analysis
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Comorbidity
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Takotsubo Cardiomyopathy
Cardiac Imaging Techniques
Risk
Antithrombins
Blood Platelets
Heart Failure
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Drug-Eluting Stents
Echocardiography
Myocardium
Endpoint Determination
Atherosclerosis
Glycogen Phosphorylase, Brain Form
Point-of-Care Systems
Diabetes Complications
Postoperative Hemorrhage
Coronary Artery Bypass, Off-Pump
Survival Rate
Multidetector Computed Tomography
Peptide Fragments
Emergency Treatment
Growth Differentiation Factor 15
A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
Purinergic P2 Receptor Antagonists
Necrosis
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
Middle East
Prevalence
Inflammation
Patient Admission
Patient Readmission
Atherectomy, Coronary
Patient Discharge
Multicenter Studies as Topic
Endothelium, Vascular
Analysis of Variance
Diabetes Mellitus
Radial Artery
Neopterin
P-Selectin
Heart Diseases
Myocardial Perfusion Imaging
Patient Selection
Partial Thromboplastin Time
The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.
Angiotensin-Converting Enzyme Inhibitors
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
Evidence-Based Medicine
An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)
Statistics, Nonparametric
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
Diagnostic Techniques, Cardiovascular
Stroke Volume
Hypolipidemic Agents
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
CD40 Ligand
Thromboplastin
Thrombectomy
Guideline Adherence
Collateral Circulation
Dogs
Reference Values
Dose-Response Relationship, Drug
Exercise Test
Death
Hemodynamics
Nephrotic Syndrome
A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
Catha
Lipids
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Nadroparin
Coronary care medicine: it's not your father's CCU anymore. (1/1612)
The management of ST-elevation MI (STEMI) has gone through four phases: 1. The "clinical observation phase"; 2. the "coronary care unit phase"; 3. the "high-technology phase"; and 4. the "evidence-based coronary care phase". A significant advance in the care of patients with acute myocardial infarction that arose as an outgrowth of the evidence-based era was introduction of a lexicon that more accurately reflected contemporary concepts of the pathophysiology underlying myocardial ischemia and infarction. Although considerable improvement has occurred in the process of care for patient with STEMI, room for improvement exists. Despite strong evidence in the literature that prompt use of reperfusion therapy improves survival of STEMI patients such treatment is underutilized and often not administered in an expeditious timeframe relative to the onset of symptom. Even in the reperfusion era, left ventricular dysfunction remains the single most important predictor of mortality following STEMI. After administration of aspirin, initiating reperfusion strategies and, where appropriate, beta blockade all STEMI patients should be considered for inhibition of the renin-angiotensin-aldosterone system. Several adjunctive pharmacotherapies have been investigated to prevent inflammatory damage in the infarct zone. Contrary to earlier beliefs that the heart is a terminally differentiated organ without the capacity to regenerate, evidence now exists that human cardiac myocytes divide after STEMI and stem cells can promote regeneration of cardiac tissue. These observations open up the possibility of myocardial replacement therapy after STEMI. (+info)Gender differences in management and outcome in non-ST-elevation acute coronary syndrome. (2/1612)
OBJECTIVE: To study gender differences in management and outcome in patients with non-ST-elevation acute coronary syndrome. DESIGN, SETTING AND PATIENTS: Cohort study of 53 781 consecutive patients (37% women) from the Register of Information and Knowledge about Swedish Heart Intensive care Admissions (RIKS-HIA), with a diagnosis of either unstable angina pectoris or non-ST-elevation myocardial infarction. All patients were admitted to intensive coronary care units in Sweden, between 1998 and 2002, and followed for 1 year. MAIN OUTCOME MEASURES: Treatment intensity and in-hospital, 30-day and 1-year mortality. RESULTS: Women were older (73 vs 69 years, p<0.001) and more likely to have a history of hypertension and diabetes, but less likely to have a history of myocardial infarction or revascularisation. After adjustment, there were no major differences in acute pharmacological treatment or prophylactic medication at discharge. Revascularisation was, however, even after adjustment, performed more often in men (OR 1.15; 95% CI, 1.09 to 1.21). After adjustment, there was no significant difference in in-hospital (OR 1.03; 95% CI, 0.94 to 1.13) or 30-days (OR 1.07; 95% CI, 0.99 to 1.15) mortality, but at 1 year being male was associated with higher mortality (OR 1.12; 95% CI, 1.06 to 1.19). CONCLUSION: Although women are somewhat less intensively treated, especially regarding invasive procedures, after adjustment for differences in background characteristics, they have better long-term outcomes than men. (+info)Association between plasma adiponectin levels and unstable coronary syndromes. (3/1612)
AIMS: Obesity is a risk factor for an acute coronary syndrome (ACS). The association between elevated body mass index (BMI) and ACS is independent of most traditional risk factors, suggesting a possible contribution of other body fat-related mediators. This study evaluated the association between adiponectin and ACS. METHODS AND RESULTS: Four hundred and ninety-nine patients undergoing coronary angiography were divided into a subgroup without (n = 331) and with ACS (n = 168). In multiple regression analysis, higher adiponectin levels were independently associated with a lower risk of ACS [odds ratio (OR) = 0.61; 95% CIs: 0.46-0.81; P < 0.001]. In contrast, a higher BMI, a history of myocardial infarction, C-reactive protein, and angiographic coronary artery disease severity were all associated with a higher risk. The greatest increase in risk for ACS was seen at adiponectin levels < or = 5.5 microg/mL. CONCLUSION: Higher plasma adiponectin levels are independently associated with a lower risk of ACS. (+info)Pregnancy-associated plasma protein A and proform eosinophilic major basic protein in the detection of different types of coronary artery disease. (4/1612)
Kryptor system was proven to be a rapid, standard method for pregnancy-associated plasma protein A and proform eosinophilic major basic protein (PAPP-A/proMBP) complex detection in coronary artery disease (CAD). No age and/or gender differences in 51 controls and 110 stable coronary artery disease (SCAD) patients were found. SCAD patients did not differ from controls and no difference in PAPP-A/proMBP levels with regards to the number of affected vessels was found. In 21 unstable angina pectoris (UAP), in 35 without and 66 with ST elevation acute myocardial infarctions (NSTEMI, STEMI respectively) patients PAPP-A/proMBP levels were increased (P=0.004 and P<0.0005, respectively). PAPP-A/proMBP levels did not correlate with cardiac troponin I (cTnI) in STEMI and NSTEMI patients. PAPP-A/ proMBP increase was more frequent than cTnI (P=0.036) within the early phase of STEMI. In NSTEMI patients PAPP-A/proMBP positivity was present in 50% of cTnI negative cases. Receiver operating characteristic (ROC) analysis revealed the highest diagnostic accuracy of PAPP-A/proMBP (0.919) in STEMI cTnI positive cases. The highest specificity/sensitivity PAPP-A/proMBP levels for particular acute coronary syndrome (ACS) types were 10.65-14.75 mIU/l. Combination of PAPP-A/proMBP with cTnI increases their diagnostic efficacy within the early phase of ACS. Our results suggest that PAPP-A/proMBP complex is involved in processes preceding vulnerable plaque development in ACS. (+info)Effects of revascularization within 14 days of hospital admission due to acute coronary syndrome on 1-year mortality in patients with previous coronary artery bypass graft surgery. (5/1612)
AIMS: To determine whether revascularization within 14 days reduces 1-year mortality in patients with a previous CABG admitted for non-ST-elevation ACS. Current guidelines for patients with acute coronary syndrome (ACS) include early revascularization. The evidence is derived from studies, in which patients with previous coronary artery by-pass graft (CABG) surgery often were excluded and thus insufficient to support a similar strategy in these high-risk patients in whom coronary interventions are associated with lower success and higher complication rates. METHODS AND RESULTS: A cohort of 10 469 patients < 80 years old from a national registry, admitted to coronary care units in Sweden, was studied. We obtained 1-year mortality data from the Swedish National Cause of Death Registry. Relative risk (RR) in patients undergoing revascularization within 14 days (n = 4269) of admission compared to those who did not (n = 6200) was calculated by using multivariable logistic regression analyses and propensity scores for the likelihood of early revascularization. At 1-year, unadjusted mortality was 5.4% in the revascularized group and 13.1% in the conservatively treated group. In multiple regression analyses, revascularization was associated with a reduction of 1-year mortality (RR 0.67; 95% CI, 0.56-0.81; P < 0.001). CONCLUSION: In patients with a previous CABG admitted for ACS, revascularization within 14 days of hospital admission was associated with a marked reduction in 1-year mortality, supporting an early invasive approach also in this subset of patients. (+info)Clinical use of clopidogrel in acute coronary syndrome. (6/1612)
Several therapeutic approaches have been developed to improve the outcome among patients with acute coronary syndrome (ACS). However, treatment with antithrombotic therapies such as oral glycoprotein IIb/IIIa inhibitors has been limited by the lack of efficacy and excess bleeding complications. As the publication of the landmark study Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE), the clinical benefit of early and intermediate-term use of combined antiplatelet agents--clopidogrel plus aspirin--in non-ST-segment elevation myocardial infarction (NSTEMI) patients became evident. Pretreatment and intermediate-term therapy with clopidogrel in NSTEMI ACS patients undergoing percutaneous coronary intervention (PCI) was further supported by the PCI-CURE trial. Recently, the results of two major trials Clopidogrel as Adjunctive Reperfusion Therapy-Thrombolysis in Myocardial Infarction 28, Clopidogrel and Metoprolol in Myocardial Infarction Trial established the pivotal role of clopidogrel in the other spectrum of ACS-STEMI. Coupled with the results from previous multicentre trials, these two studies provide a guide for the early and long-term use of clopidogrel in the whole spectrum of ACS. A review summarising the results of the recent clinical trials and a discussion on its implications for the clinical management of ACS is presented. (+info)64-Slice CT coronary angiography in patients with non-ST elevation acute coronary syndrome. (7/1612)
BACKGROUND: A high diagnostic accuracy of 64-slice CT coronary angiography (CTCA) has been reported in selected patients with stable angina pectoris, but only scant information is available in patients with non-ST elevation acute coronary syndrome (ACS). OBJECTIVES: To study the diagnostic performance of 64-slice CTCA in patients with non-ST elevation ACS. PATIENTS AND METHODS: 64-slice CTCA was performed in 104 patients (mean (SD) age 59 (9) years) with non-ST elevation ACS. Two independent, blinded observers assessed all coronary arteries for stenosis, using conventional quantitative angiography as a reference. Coronary lesions with >or=50% luminal narrowing were classified as significant. RESULTS: Conventional coronary angiography demonstrated the absence of significant disease in 15% (16/104) of patients, and the presence of single-vessel disease in 40% (42/104) and multivessel disease in 44% (46/104) of patients. Sensitivity for detecting significant coronary stenoses on a patient-by-patient analysis was 100% (88/88; 95% CI 95 to 100), specificity 75% (12/16; 95% CI 47 to 92), and positive and negative predictive values were 96% (88/92; 95% CI 89 to 99) and 100% (12/12; 95% CI 70 to 100), respectively. CONCLUSION: 64-slice CTCA has a high sensitivity to detect significant coronary stenoses, and is reliable to exclude the presence of significant coronary artery disease in patients who present with a non-ST elevation ACS. (+info)Relationship between circulating endothelial cells and the predicted risk of cardiovascular events in acute coronary syndromes. (8/1612)
AIMS: The quantification of circulating endothelial cells (CECs) in whole blood is a novel marker of direct endothelial injury and shows promise as a potential biomarker of cardiovascular (CV) risk. The inter-relationship(s) between CECs and predicted CV risk has not been explored in large cohort of 'high-risk' patients. We hypothesized that there would be a significant relationship between increasing CEC counts and predicted CV risk in a broad spectrum of patients presenting with acute coronary syndrome (ACS). METHODS AND RESULTS: We studied 197 patients (aged 40-80 years) admitted with a confirmed diagnosis of unstable angina (UA), non-ST-elevation myocardial infarction (MI, NSTEMI), or ST-elevation MI (STEMI). CEC counts were performed on venous whole blood using the immunobead technique. Four well-validated ACS risk scores [(PURSUIT and TIMI for NSTEMI/UA) TIMI (STEMI) and GRACE (all ACS)] were calculated from the initial clinical history and electrocardiogram, as well as from values of laboratory parameters collected within 12 h of admission. We included a healthy control (HC) group of 50 matched patients in order to quantify the accuracy of CEC counts for the diagnosis of ACS and to compare disease vs. HC counts. CEC counts were significantly higher in the disease group when compared with the HC group. CEC counts significantly increased with increasing severity of disease (that is, UA vs. NSTEMI vs. STEMI; P = 0.002). CEC counts were higher among patients with clinical evidence of heart failure (Killip Class II-IV) when compared with those without (Killip Class I) on admission (P < 0.0001). There was a significant correlation between CEC counts and predicted CV risk for each of the four ACS risk scoring schemes (all P < 0.05). The area under the receiver-operating characteristic (ROC) curve (AUC) for the entire ACS cohort was 0.82 (95% CI: 0.76-0.88; P < 0.0001). A CEC count of >or=7/mL provided a positive predictive value of 90.6% (95% CI: 85.6-95.7%) and a negative predictive value of 53.5% (41.9-65.1%) for the diagnosis of MI (NSTEMI/STEMI) in the presence of an appropriate clinical presentation. CONCLUSION: There is a significant and positive correlation between increasing CECs and increasing CV risk in ACS. The diagnostic accuracy of CECs in this setting is only 'moderate'. Whilst it is good at confirming the presence of MI, a CEC value of <7.0/mL is less reliable at confidently excluding patients without disease. (+info)
Acute Coronary Syndrome: Current Treatment - - American Family Physician
Coronary CT Angiography in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome - Research - The Capital Region of...
Coronary CT Angiography in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome - Forskning - Region Hovedstaden
Association among leukocyte count, mortality, and bleeding in patients with non-ST-segment elevation acute coronary syndromes ...
Ticagrelor (Brilinta) for Secondary Prevention of Thrombotic Events Following Acute Coronary Syndrome
-...
Study Evaluating How Patients With Acute Coronary Syndrome Are Managed During 2 Years After Discharge - Full Text View -...
Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15years.
Predictors of stroke within 30 days in patients with non-ST-segment elevation acute coronary syndromes
PDF] Coronary CT Angiography in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome. | Scinapse
COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England. - Nuffield Department of...
Racial Differences Among High-Risk Patients Presenting With Non-ST-Segment Elevation Acute Coronary Syndromes (Results from the...
Effect of alirocumab, a monoclonal antibody to PCSK9, on long-term cardiovascular outcomes following acute coronary syndromes:...
Prediction of Cardiovascular Events in Vulnerable Patients Following Acute Coronary Syndrome - Tabular View - ClinicalTrials.gov
Immediate versus deferred coronary angioplasty in non-ST-elevation acute coronary syndromes
Multimorbidity, polypharmacy, and drug-drug-gene interactions following a non-ST elevation acute coronary syndrome: analysis of...
Vorapaxar in acute coronary syndrome patients undergoing coronary artery bypass graft surgery: Subgroup analysis from the...
Abstract 1588: Worldwide Gender Bias in Angiographic Obstructive Acute Coronary Syndromes? | Circulation
Prognostic relations between inflammatory markers and mortality in diabetic patients with non-ST elevation acute coronary...
Magnitude and consequences of undertreatment of high-risk patients with non-ST segment elevation acute coronary syndromes:...
Antiplatelet Agents in Acute Coronary Syndromes
Acute coronary syndrome - Answers on HealthTap
Sustained Ventricular Tachycardia and Ventricular Fibrillation Complicating Non-ST-Segment Elevation Acute Coronary Syndromes |...
Gender differences in management and outcome in non-ST-elevation acute coronary syndrome
Timing of Angiography With a Routine Invasive Strategy and Long-Term Outcomes in Non-ST-Segment Elevation Acute Coronary...
The paradoxical use of cardiac catheterization in patients with non-ST-elevation acute coronary syndromes: lessons from the Can...
New Educational Materials for Acute Coronary Syndrome | Thrombosis Canada - Thrombose Canada
High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study<...
Classification and regression tree analysis in acute coronary syndrome patients
Predictors of long-term outcome of percutaneous coronary intervention in elderly patients with acute coronary syndrome - a -...
Duration of eptifibatide infusion after percutaneous coronary intervention and outcomes among high-risk patients with non-ST...
Management of Acute Coronary Syndromes - Free PDF Ebooks Downloads
Surgical Versus Percutaneous Coronary Revascularization in Patients With Diabetes and Acute Coronary Syndromes<...
Acute Coronary Syndrome: Electrocardiogram
My Site - Chapter 27: Management of Acute Coronary Syndromes
Identifying mortality risk factors amongst acute coronary syndrome patients admitted to Arabian Gulf hospitals using machine...
Current evidence for monitoring platelet reactivity in acute coronary syndrome: A plea for individualized antiplatelet...
Current evidence for monitoring platelet reactivity in acute coronary syndrome: A plea for individualized antiplatelet...
Acute Coronary Syndromes | Medscape
Chest Pain Suggestive of Acute Coronary Syndrome - Premier Radiology Services
Coronary Artery Disease
Kidney Dysfunction and Long-Term Outcome in Post-PCI Acute Coronary Syndrome Patients Treated by High-Dose Tirofiban: The Role...
Acute Coronary Syndromes Clinical Care Standard | Safety and Quality
Cardiogenic shock in patients with acute coronary syndromes - Oxford Medicine
Hs-troponin i followed by CT angiography improves acute coronary syndrome risk stratification accuracy and work-up in acute...
Elevation of ceramide and activation of secretory acid sphingomyelinase in patients with acute coronary syndromes<...
Prognostic Significance of Relative Hyperglycemia after Percutaneous Coronary Intervention in Patients with and without...
Effect of revascularization on mortality associated with an elevated white blood cell count in acute coronary syndromes
Endotoxemia is associated with acute coronary syndrome in patients with end stage kidney disease<...
The cost of inpatient death associated with acute coronary syndrome | VHRM
Regional to tertiary inter-hospital transfer versus in-house percutaneous coronary intervention in acute coronary syndrome -...
Early and long-term outcomes after surgical and percutaneous myocardial revascularization in patients with non-st-elevation...
Cardiac Troponins in Suspected Acute Coronary Syndrome - ScienceOpen
Fasting Triglycerides Predict Recurrent Ischemic Events in Patients With Acute Coronary Syndrome Treated With Statins
Choosing between Enoxaparin and Fondaparinux for the management of patients with acute coronary syndrome: A systematic review...
Prognostic value of N-terminal pro-B-type natriuretic peptide in patients with acute coronary syndromes undergoing left main...
Serval - Prognostic value of elevated lipoprotein(a) in patients with acute coronary syndromes.
Risk stratification in acute coronary syndrome using cardiac troponin I. - Free Online Library
Inflammatory marker comparison between patients with acute coronary syndrome undergoing on-pump versus off-pump coronary artery...
Takotsubo cardiomyopathy-Differentiation from acute coronary syndrome by electrocardiography and biochemistry
Optical coherence tomography to reveal strut malapposition due to thrombus resolution 3 weeks after acute coronary syndrome -...
Acute esophageal necrosis masquerading acute coronary syndrome | Autopsy and Case Reports
Gender-specific 11-dehydro-thromboxane B2 levels in acute coronary syndrome and its association with clinical outcomes -...
Interactions between pro-inflammatory cytokines and statins on depression in patients with acute coronary syndrome - DRO
Acute Coronary Syndrome Screening and Diagnostic Practice Variation<...
Top Clinics for Acute Coronary Syndrome, Heart Care Surgery in Portugal
Best 50+ Clinics for Acute Coronary Syndrome in Malta
Abstract 256: Readmission Avoidability in Acute Coronary Syndrome Patients | Circulation: Cardiovascular Quality and Outcomes
Nadroparine calcium or enoxaparine in acute coronary syndrome patients suffering renal insufficiency: The nadroparin versus...
Frailty and quality of life in elderly patients with acute coronary sy | CIA
An evaluation of the effectiveness of self‐management interventions for people with type 2 diabetes after an acute coronary...
Safety and efficacy of bivalirudin in high-risk patients admitted through the emergency department<...
Erectile dysfunction: new research shows incidence rate linked to type and severity of coronary artery disease
Effects of colchicine on neutrophil function in acute coronary syndrome (ACS) patients • Heart Research Institute NZ
Commonly prescribed drugs
"ESC Guidelines on Acute Coronary Syndromes (ACS) in patients presenting without persistent ST-segment elevation (Management of ... "Acute Coronary Syndrome , Pharmacotherapy: A Pathophysiologic Approach, 11e , AccessPharmacy , McGraw-Hill Medical". ... "Meta-Analysis of the Relative Efficacy and Safety of Oral P2Y12 Inhibitors in Patients With Acute Coronary Syndrome". The ... This disease can be classified into acute and chronic coronary heart disease. This disease caused 8.9 million deaths in 2019 ...
Valentín Fuster
"The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes". New England Journal of Medicine. 326 (5): 310- ... Fuster, V.; Fayad, Z. A.; Badimon, J. J. (1999). "Acute coronary syndromes: biology". Lancet. 353 Suppl 2: SII5-9. doi:10.1016/ ... 1990s: Demonstrating that acute coronary events arise from small plaques, explaining their unpredictability, and developing ... 2000s: Following upon experience with CABG and DES for revascularization in patients with diabetes and multivessel coronary ...
Troponin
2001). "Acute coronary syndromes. The diagnostic role of troponins". Thromb. Res. 103 (1): 63-69. CiteSeerX 10.1.1.500.6908. ... October 1996). "Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes ... in people with chest pain or acute coronary syndrome. A person who recently had a myocardial infarction would have an area of ... "2014 AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes: A Report of the American ...
Heart
"Acute Coronary Syndrome Workup". Medscape. Archived from the original on 6 August 2016. Retrieved 14 August 2016. Davidson's ... These are the left main coronary artery and the right coronary artery. The left main coronary artery splits shortly after ... Long QT syndrome is the most common form of cardiac channelopathy. Long QT Syndrome (LQTS) - Mostly hereditary. On EKG can be ... A small amount of blood from the coronary circulation also drains into the right atrium via the coronary sinus, which is ...
Atherosclerosis
Didangelos A, Simper D, Monaco C, Mayr M (May 2009). "Proteomics of acute coronary syndromes". Current Atherosclerosis Reports ... A number of procedures may also be carried out such as percutaneous coronary intervention, coronary artery bypass graft, or ... A number of procedures may also be carried out such as percutaneous coronary intervention, coronary artery bypass graft, or ... Werner syndrome (WS) is a premature aging condition in humans. WS is caused by a genetic defect in a RecQ helicase that is ...
Béla Merkely
... arrhythmias and acute coronary syndromes; sport cardiology, cardiac remodelling of elite athletes. Since 1994, he has been ...
Chest pain
If acute coronary syndrome ("heart attack") is suspected, many people are admitted briefly for observation, sequential ECGs, ... Acute coronary syndrome Stable or unstable angina Myocardial infarction ("heart attack"): People usually complained of a ... However, both atypical and typical symptoms of acute coronary syndrome can occur, and in general a history cannot be enough to ... The rate of chest pain as a symptom of acute coronary syndrome varies among populations based upon age, sex, and previous ...
Rosuvastatin
Aggarwal RK, Showkathali R (June 2013). "Rosuvastatin calcium in acute coronary syndromes". Expert Opinion on Pharmacotherapy. ... April 2006). "Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial". JAMA ...
Door-to-balloon
Section 5. Initial management of acute coronary syndromes". Resuscitation. 67 Suppl 1: S87-96. doi:10.1016/j.resuscitation. ... expertly performed primary percutaneous coronary intervention over thrombolytic therapy for acute ST elevation myocardial ... American College of Cardiology (ACC) Door to Balloon (D2B) Initiative Q&A: Improving door-to-balloon time for acute MI - ... As of 2006 in the United States, fewer than half of STEMI patients received reperfusion with primary percutaneous coronary ...
Colchicine
Malik J, Javed N, Ishaq U, Khan U, Laique T (May 2020). "Is There a Role for Colchicine in Acute Coronary Syndromes? A ... Imazio M, Andreis A, Brucato A, Adler Y, De Ferrari GM (October 2020). "Colchicine for acute and chronic coronary syndromes". ... On 29 July 2009, colchicine won FDA approval in the United States as a stand-alone drug for the treatment of acute flares of ... According to one review, colchicine poisoning by overdose (range of acute doses of 7 to 26 mg) begins with a gastrointestinal ...
Health effects of tobacco
... in hospital admissions for acute coronary syndrome. 67% of the decrease occurred in non-smokers. Smoking most commonly leads to ... "Smoke-free legislation and hospitalizations for acute coronary syndrome" (PDF). The New England Journal of Medicine. 359 (5): ... in relation to reports that smokers appeared to have unexpectedly good short-term outcomes following acute coronary syndrome or ... Xu C, Lu HX, Wang YX, Chen Y, Yang SH, Luo YJ (2016). "Association between smoking and the risk of acute mountain sickness: a ...
Abid Ali (cricketer)
He was later diagnosed with acute coronary syndrome. The following day, he underwent an angioplasty. "Abid Ali". ESPN Cricinfo ...
Deaths in April 2021
Takashi Tachibana, 80, Japanese journalist, acute coronary syndrome. Chandro Tomar, 89, Indian sharpshooter, COVID-19. Jevgeni ...
Aly Saad
Prima- vista multi-vessel percutaneous coronary intervention in haemodynamically stable patients with acute coronary syndromes ... on Percutaneous Coronary Intervention (PCI) Registry (2008-2010) Euro Hear Survey (EHS) on Acute Coronary Syndrome III (ACS III ... "Predictors of hospital mortality in the elderly undergoing percutaneous coronary intervention for acute coronary syndromes and ... Acute Coronary Syndrome (ACS) snapshot Registry Puymirat, Etienne; Battler, Alex; Birkhead, John; Bueno, Hector; Clemmensen, ...
Darapladib
... and urgent coronary revascularization compared with placebo in acute coronary syndrome patients treated with standard medical ... "GSK announces phase III study with darapladib did not meet primary endpoint in patients following an acute coronary syndrome". ... Thompson PL, Nidorf SM, Eikelboom J (August 2013). "Targeting the unstable plaque in acute coronary syndromes". Clinical ... GSK announced that the drug had failed to meet Phase III endpoints in a trial of 16,000 patients with acute coronary syndrome ( ...
Glycogen phosphorylase isoenzyme BB
The enzyme is one of the "new cardiac markers" which are discussed to improve early diagnosis in acute coronary syndrome. A ... May 2005). "Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome". Clin. Chem. 51 (5 ... 2005). "Glycogen phosphorylase BB in acute coronary syndromes". Clin. Chem. Lab. Med. 43 (12): 1351-8. doi:10.1515/CCLM. ...
Alirocumab
"Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome". N Engl J Med. 379 (22): 2097-2107. doi:10.1056/ ...
Dyslipidemia
... and nonfatal stroke in patients after acute coronary syndromes. This agent consists of eicosapentaenoic acid (EPA), an omega-3 ... "Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes". New England Journal of Medicine. 372 (25): 2387-2397. doi: ... of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes". ... "The Lipid Research Clinics Coronary Primary Prevention Trial Results: I. Reduction in Incidence of Coronary Heart Disease". ...
Biological response modifier
Clinical use: Acute coronary syndromes, percutaneous transluminal coronary angioplasty. Toxicity: Bleeding, thrombocytopenia. ...
Troponin I
Danese, E; Montagnana, M (2016). "An historical approach to the diagnostic biomarkers of acute coronary syndrome". Annals of ... 59(3): p. 172-8. Tanindi, Asil; Cemri, Mustafa (2011). "Troponin elevation in conditions other than acute coronary syndromes". ... as a prognostic marker in patients with acute coronary syndrome and to identify the risk (low, moderate and elevated) of future ... 2016). "High-Sensitivity Cardiac Troponin, Statin Therapy, and Risk of Coronary Heart Disease". Journal of the American College ...
Prasugrel
... in people with acute coronary syndrome (ACS) who are to be managed with percutaneous coronary intervention (PCI). Prasugrel is ... November 2007). "Prasugrel versus clopidogrel in patients with acute coronary syndromes". The New England Journal of Medicine. ... "Reappraisal of thienopyridine pretreatment in patients with non-ST elevation acute coronary syndrome: a systematic review and ... "Pretreatment with Prasugrel in Non-ST-Segment Elevation Acute Coronary Syndromes". New England Journal of Medicine. 369 (11): ...
Phentolamine
"Phentolamine therapy for cocaine-association acute coronary syndrome (CAACS)". Journal of Medical Toxicology. 2 (3): 108-11. ... Rowbotham MC (June 2006). "Pharmacologic management of complex regional pain syndrome". The Clinical Journal of Pain. 22 (5): ... Phentolamine also has diagnostic and therapeutic roles in complex regional pain syndrome (reflex sympathetic dystrophy). ... as they can cause unopposed α-adrenergic mediated coronary vasoconstriction, worsening myocardial ischemia and hypertension. It ...
Vorapaxar
2012). "Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes". New England Journal of Medicine. 366 (1): 20-33. ... by a pooled analysis of data that studied 42000 patients with history of thrombotic vascular disease or acute coronary syndrome ... trial comparing vorapaxar with placebo in addition to standard therapy in 12,944 patients who had acute coronary syndromes, ... stroke or urgent coronary revascularization by 12 percent compared to placebo plus standard of care (11.2 percent vs. 12.4 ...
Fondaparinux
"Comparison of fondaparinux and enoxaparin in acute coronary syndromes". The New England Journal of Medicine. 354 (14): 1464- ... Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators) (April 2006). " ... February 2008). "The role of fondaparinux as an adjunct to thrombolytic therapy in acute myocardial infarction: a subgroup ...
Myocardial infarction
It is a type of acute coronary syndrome, which describes a sudden or short-term change in symptoms related to blood flow to the ... Unlike the other type of acute coronary syndrome, unstable angina, a myocardial infarction occurs when there is cell death, ... December 2014). "2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report ... August 2017). "Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome: a meta- ...
P2Y12
October 2019). "Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes". The New England Journal of Medicine. 381 ( ... October 2014). "Reappraisal of thienopyridine pretreatment in patients with non-ST elevation acute coronary syndrome: a ... remains the first-line treatment for acute coronary syndrome. A 2019 randomized trial suggested that prasugrel is superior to ... addition to aspirin should be administered for up to 12 months to most patients with non-ST-elevation acute coronary syndrome. ...
Deaths in July 2018
Takahiro Satō, 41, Japanese manga writer, acute coronary syndrome. Bradford A. Smith, 86, American astronomer, complications of ...
Avijit Lahiri
"Myocardial perfusion imaging versus biochemical markers in acute coronary syndromes". Nuclear Medicine Communications. 24 (10 ... He has contributed to a number of clinical trials, including the first trials of Carvedilol, in heart failure and acute ... Sabharwal, N K (2003). "Role of myocardial perfusion imaging for risk stratification in suspected or known coronary artery ... Coronary Artery Calcium Scanning) in the UK. Contributed in early diagnostic imaging in asymptomatic diabetes. Referenced in ...
Nitrous oxide
Its use for acute coronary syndrome is of unknown benefit. In Britain and Canada, Entonox and Nitronox are used commonly by ... 2010). "Part 10: acute coronary syndromes: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and ... oral surgery and acute coronary syndrome (includes heart attacks). Its use during labour has been shown to be a safe and ...
Ulf Landmesser
"2015 ESC Guidelines for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment ... "Swiss Working Group for Interventional Cardiology and Acute Coronary Syndromes". Retrieved 23 November 2016. "2016-2018 EAPC ... "Interventional Cardiology and Acute Coronary Syndrome" of the Swiss Society for Cardiology, board member of the group " ... Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the ...
Gallbladder disease
While in acute cases, patients take antibiotics for complications such as abscesses, pain control, and nothing to eat until a ... Postcholecystectomy syndrome (cholesterosis, hydrops, perforation, fistula). *Xanthogranulomatous cholecystitis is a rare form ... "Effect of estrogen plus progestin on risk for biliary tract surgery in postmenopausal women with coronary artery disease. The ... Additionally, in acute cases, a leukocytosis, an increase in white blood cell count, is found. In chronic cases, a ...
Pleural effusion
Meigs's syndrome (ascites and pleural effusion due to a benign ovarian tumor), and ovarian hyperstimulation syndrome.[6] ... coronary artery bypass surgery, abdominal surgery, endoscopic variceal sclerotherapy, radiation therapy, liver or lung ... Nephrotic syndrome, leading to the loss of large amounts of albumin in urine and resultant low albumin levels in the blood and ... Nephrotic syndrome. *Acute atelectasis[4]. *Myxedema. *Peritoneal dialysis. *Meigs's syndrome. *Obstructive uropathy ...
Mechanical ventilation
Acute renal failure. Acute respiratory distress syndrome. Acute liver failure. Respiratory failure. Multiple organ dysfunction ... Acute lung injury, including acute respiratory distress syndrome (ARDS),[7] trauma, or COVID-19[8] ... tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome". ... One of the primary complications that presents in patients mechanically ventilated is acute lung injury (ALI)/acute respiratory ...
Estradiol
"17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart ... Males with certain sex chromosome genetic conditions, such as Klinefelter's syndrome, will have a higher level of estradiol.[20 ... "Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent ... Improvement in arterial blood flow has been demonstrated in coronary arteries.[39] ...
Ateroskleroza - Wikipedija, prosta enciklopedija
"Proteomics of acute coronary syndromes" (PDF). Current atherosclerosis reports. 11 (3): 188-95. doi:10.1007/s11883-009-0030-x. ...
Stress (biology)
Specifically, acute and chronic stress have been shown to raise serum lipids and are associated with clinical coronary events.[ ... Acute stressors affect an organism in the short term; chronic stressors over the longer term. The general adaptation syndrome ( ... chronic fatigue syndrome,[57] depression,[58] as well as other mental illnesses[5] and functional somatic syndromes.[59] ... Acute time-limited stressors, or stressors that lasted less than two hours, results in an up regulation of natural immunity and ...
Arrhythmia
Acute coronary syndrome *Myocardial infarction. *Unstable angina. Sequelae. *hours *Hibernating myocardium. *Myocardial ... Sudden arrhythmic death syndrome[edit]. Sudden arrhythmic death syndrome (SADS), is a term used as part of sudden unexpected ... Causes of SADS in young people include viral myocarditis, long QT syndrome, Brugada syndrome, Catecholaminergic polymorphic ... Wolff-Parkinson-White syndrome is due to an extra pathway in the heart that is made up of electrical muscle tissue. This tissue ...
Utah - Wikipédia Sunda, énsiklopédi bébas
... acute coronary syndromes: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency ...
Anaphylaxis
Those with underlying coronary disease are at greater risk of cardiac effects from anaphylaxis.[17] The coronary spasm is ... "Acute symptoms of drug hypersensitivity (urticaria, angioedema, anaphylaxis, anaphylactic shock)" (PDF). The Medical Clinics ... Allergic reaction, angioedema, asthma exacerbation, carcinoid syndrome[2]. Treatment. Epinephrine, intravenous fluids[1]. ... Coronary artery spasm may occur with subsequent myocardial infarction, dysrhythmia, or cardiac arrest.[3][14] ...
Liver function tests
Gilbert's syndrome and Crigler-Najjar syndrome have defects in the UDP-glucuronyl-transferase enzyme, affecting bilirubin ... In acute appendicitis, total bilirubin can rise from 20.52 μmol/L to 143 μmol/L. In pregnant women, the total bilirubin level ... T and I and creatine kinase-MB as markers of myocardial injury and predictors of outcome following percutaneous coronary ... In hyperemesis gravidarum, GGT level value can reach 45 IU/L, 17 IU/L in pre-eclampsia, and 35 IU/L in HELPP syndrome.[7] ...
Acute eosinophilic leukemia
... acute eosinophilic leukemia have a propensity for developing bronchospasm as well as symptoms of the acute coronary syndrome ... Acute eosinophilic leukemia (AEL) is a rare subtype of acute myeloid leukemia with 50 to 80 percent of eosinophilic cells in ... "Acute Myeloid Leukemia (AML) Subtypes and Prognostic Factors". www.cancer.org. Retrieved 2022-02-03.. ... It can arise de novo or may develop in patients having the chronic form of a hypereosinophilic syndrome. Patients with ...
Junctional ectopic tachycardia
Acute coronary syndrome *Myocardial infarction. *Unstable angina. Sequelae. *hours *Hibernating myocardium. *Myocardial ... This syndrome, which may also referred to as His bundle tachycardia, is resistant to therapy and can be difficult to treat.[3][ ... Junctional ectopic tachycardia (JET) is a rare syndrome of the heart that manifests in patients recovering from heart surgery.[ ... a rough triangle with points at the coronary sinus, the tendon of Todaro, and the tricuspid valve).[4] ...
Aspirin
"Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation" (PDF). ... Reye's syndromeEdit. Main article: Reye's syndrome. Reye's syndrome, a rare but severe illness characterized by acute ... After percutaneous coronary interventions (PCIs), such as the placement of a coronary artery stent, a U.S. Agency for ... Aspirin overdose can be acute or chronic. In acute poisoning, a single large dose is taken; in chronic poisoning, higher than ...
மாரடைப்பு - தமிழ் விக்கிப்பீடியா
2003). "Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: ... "Symptom presentation of women with acute coronary syndromes: myth vs reality". Arch. Intern. Med. 167 (22): 2405-13. doi: ... acute coronary syndrome)[17]. நெஞ்சு வலி வெவ்வேறு சந்தர்ப்பங்களில் தோன்றலாம், எனவே நெஞ்சு வலியினை உருவாக்கும் பிற பெருங்கேடுகள் ... www.heart.org/HEARTORG/Conditions/HeartAttack/AboutHeartAttacks/Acute-Coronary-Syndrome_UCM_428752_Article.jsp#.T1HskxzCqYk. ...
List of ICD-9 codes 390-459: diseases of the circulatory system
Other acute and subacute forms of ischemic heart disease 411.0 Postmyocardial infarction syndrome 411.1 Intermediate coronary ... acute, inferoposterior 410.4 MI, acute, other inferior wall, NOS 410.5 MI, acute, other lateral wall 410.6 MI, acute, true ... benign 410 Acute myocardial infarction 410.0 MI, acute, anterolateral 410.1 MI, acute, anterior, NOS 410.2 MI, acute, ... acute, nonspecific 421 Acute and subacute endocarditis 421.0 Endocarditis, acute, bacterial 422 Acute myocarditis 422.9 Other ...
Sumatriptan
"Zecuity Approved by the FDA for the Acute Treatment of Migraine". nupathe.com. Archived from the original on 7 January 2016. ... Serious side effects may include serotonin syndrome, heart attacks, strokes, and seizures. With excessive medication overuse ... Events reported have included coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular ... Clinical trial number NCT00724815 for "The Efficacy and Tolerability of NP101 Patch in the Treatment of Acute Migraine (NP101- ...
Bilirubin glucuronide
In Dubin-Johnson syndrome, impaired biliary excretion of bilirubin glucuronide is due to a mutation in the canalicular multiple ... Press, Dove (2018-03-07). "Acute bilirubin encephalopathy and its progression to kernicterus: cur - RRN". Research and Reports ... there were some studies that showed an inverse correlation between serum bilirubin level and prevalences of ischemic coronary ... Dubin-Johnson syndrome is associated with inability of the hepatocytes to secrete conjugated bilirubin after it has been formed ...
Johann Bauersachs
"Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high‐risk combination. A statement from the Acute ... "Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high-risk combination. A statement from the Acute ... "Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high-risk combination. A statement from the Acute ... He is widely recognized for his scholarly contributions to the domains of acute coronary syndrome, left ventricular repair and ...
Levothyroxine
... starting at higher doses may cause an acute coronary syndrome or an abnormal heart rhythm. Hypothyroidism is common among ... Acute overdose may cause fever, hypoglycemia, heart failure, coma, and unrecognized adrenal insufficiency. Acute massive ... Levothyroxine absorption is increased by fasting and decreased in certain malabsorption syndromes, by certain foods, and with ... people with acute myocardial infarction, and people with thyrotoxicosis of any etiology. Levothyroxine is also contraindicated ...
Meldonium
... may be used to treat coronary artery disease. These heart problems may sometimes lead to ischemia, a condition where ... This, in summary, shows that meldonium given in acute doses could be beneficial for the treatment of seizures and alcohol ... It is also used in cases of cerebral ischemia, ocular ischemic syndrome and other ocular disease caused by disturbed arterial ... Zvejniece, L; Svalbe, B; Makrecka, M; Liepinsh, E; Kalvinsh, I; Dambrova, M (2010). "Mildronate exerts acute anticonvulsant and ...
Lyme disease
... such as diverticulitis and acute coronary syndrome. Diagnosis of late-stage Lyme disease is often complicated by a multifaceted ... Garin-Bujadoux syndrome, Bannwarth syndrome, Afzelius's disease, Montauk Knee or sheep tick fever. Since 1976 the disease is ... In this syndrome, radicular pain tends to start in the same body region as the initial erythema migrans rash, if there was one ... The full syndrome now known as Lyme disease was not recognized until a cluster of cases originally thought to be juvenile ...
Heart-type fatty acid binding protein
H-FABP is recommended to be measured with troponin to identify myocardial infarction and acute coronary syndrome in patients ... "Heart-type fatty acid-binding protein predicts long-term mortality after acute coronary syndrome and identifies high-risk ... protein predicts long-term mortality and re-infarction in consecutive patients with suspected acute coronary syndrome who are ... H-FABP has been proven to significantly predict 30-day mortality in acute pulmonary embolism. H-FABP is more effective than ...
List of circulatory system conditions
Ischemic heart diseases Angina pectoris Acute coronary syndrome Acute myocardial infarction See also Category:Valvular heart ... Angina Acute coronary syndrome Anomic aphasia Aortic dissection Aortic regurgitation Aortic stenosis Apoplexy Apraxia ... Lenegre-Lev syndrome) Long QT syndrome Lown-Ganong-Levine syndrome Multifocal atrial tachycardia Wolff-Parkinson-White syndrome ... Andersen syndrome, Long QT syndrome 7; Periodic paralysis, potassium-sensitive cardiodysrhythmic type) Ashman phenomenon ( ...
Effects of cannabis
Any episode of acute psychosis that accompanies cannabis use usually abates after six hours, but in rare instances, heavy users ... Chocron, Yaniv; Zuber, Jean-Philippe; Vaucher, Julien (2019). "Cannabinoid hyperemesis syndrome". BMJ. 366: l4336. doi:10.1136/ ... particularly those with some degree of coronary artery or cerebrovascular disease, poses greater risks due to the resulting ... Acute effects while under the influence can sometimes include euphoria. Although some assert that cannabidiol (CBD), another ...
Cardiac catheterization
Acute coronary syndromes: ST elevation MI (STEMI), non-ST Elevation MI (NSTEMI), and unstable angina Evaluation of coronary ... Coronary angiography is a diagnostic procedure that allows visualization of the coronary vessels. Fluoroscopy is used to ... A common example of cardiac catheterization is coronary catheterization that involves catheterization of the coronary arteries ... where it can be maneuvered into the coronary arteries through the coronary ostia. In this position, the interventional ...
Pheochromocytoma
Acute Renal Failure: Several reports have detailed rhabdomyolysis (rapid skeletal muscle breakdown) leading to acute kidney ... Multiple organ dysfunction syndrome (MODS): Caused by an elevated inflammatory response, multiple organ dysfunction is a severe ... Norepinephrine (a catecholamine) is hypothesized to result in damaged cardiac tissue by inhibiting coronary blood flow and ... Furthermore, if an acute adrenal hemorrhage is suspected in a pheochromocytoma patient, ultrasound is a quick, painless, ...
Alien hand syndrome
described the case of a woman with severe coronary heart disease. One week after undergoing coronary artery bypass grafting, ... Actually, when AHS originates from focal injury of acute onset, recovery usually occurs within a year. One theory is that ... Alien hand syndrome (AHS) or Dr. Strangelove syndrome is a category of conditions in which a person experiences their limbs ... Apraxia and Related Syndromes at eMedicine Kischka, U; Ettlin, TM; Lichtenstern, L; Riedo, C (1996). "Alien hand syndrome of ...
Telomerase
Premature aging syndromes including Werner syndrome, Progeria, Ataxia telangiectasia, Ataxia-telangiectasia like disorder, ... "Dynamics of telomerase activity in response to acute psychological stress". Brain, Behavior, and Immunity. 24 (4): 531-9. doi: ... they report that their emotional stress is at a maximum and that telomerase was active at the site of blockages in coronary ... Bloom syndrome, Fanconi anemia and Nijmegen breakage syndrome are associated with short telomeres. However, the genes that have ...
Health in Turkey
... caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was confirmed to have reached Turkey on 11 ... Reported mortality from coronary heart disease (CHD) amongst Turkish women is the highest in Europe. Despite the public health ... "Istanbul Journal; 'Natasha Syndrome' Brings On a Fever in Turkey". New York Times. 17 April 1993. Retrieved 1 March 2019. ...
Vulnerable plaque
Some of the CT derived plaque characteristics can help predict for acute coronary syndrome. In addition, because these lesions ... quantification of coronary artery disease using cardiac CT-angiography to predict for future acute coronary syndrome". J Am ... "Frequency of Cholesterol Crystals in Culprit Coronary Artery Aspirate During Acute Myocardial Infarction and Their Relation to ... While a single ruptured plaque can be identified during autopsy as the cause of a coronary event, there is currently no way to ...
Acute Coronary Syndrome Guidelines: Guidelines Summary
Acute coronary syndrome (ACS) refers to a spectrum of clinical presentations ranging from those for ST-segment elevation ... encoded search term (Acute Coronary Syndrome) and Acute Coronary Syndrome What to Read Next on Medscape ... for the Acute Coronary Syndrome Chapter Collaborators. Part 5: Acute coronary syndromes: 2015 international consensus on ... Fast Five Quiz: Atrial Fibrillation and Acute Coronary Syndrome * Fast Five Quiz: Test Your Knowledge of Acute Coronary ...
Acute coronary syndrome: MedlinePlus Medical Encyclopedia
Acute coronary syndrome is a term for a group of conditions that suddenly stop or severely reduce blood from flowing to the ... Acute coronary syndrome is a term for a group of conditions that suddenly stop or severely reduce blood from flowing to the ... Giugliano RP, Braunwald E. Non-ST elevation acute coronary syndromes. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, ... 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American ...
Browsing by Subject "Acute Coronary Syndrome"
Improving outcomes for acute coronary syndrome in the Russian Federation: an example of regionalization of services for ... In-hospital complications and 1-year outcome of acute coronary syndrome in patients with hypertension: findings from the 2nd ... Within the framework of the Federal Cardiovascular Programme, services for acute coronary syndrome (ACS) were transformed ... in 2008-09 we investigated the in-hospital complications and 1-year outcome of acute coronary syndrome [ACS] in patients with ...
Acute Coronary Syndrome: Practice Essentials, Background, Etiology
Acute coronary syndrome (ACS) refers to a spectrum of clinical presentations ranging from those for ST-segment elevation ... encoded search term (Acute Coronary Syndrome) and Acute Coronary Syndrome What to Read Next on Medscape ... for the Acute Coronary Syndrome Chapter Collaborators. Part 5: Acute coronary syndromes: 2015 international consensus on ... Fast Five Quiz: Atrial Fibrillation and Acute Coronary Syndrome * Fast Five Quiz: Test Your Knowledge of Acute Coronary ...
Browsing by Subject "Acute Coronary Syndrome"
Improving outcomes for acute coronary syndrome in the Russian Federation: an example of regionalization of services for ... In-hospital complications and 1-year outcome of acute coronary syndrome in patients with hypertension: findings from the 2nd ... Within the framework of the Federal Cardiovascular Programme, services for acute coronary syndrome (ACS) were transformed ... in 2008-09 we investigated the in-hospital complications and 1-year outcome of acute coronary syndrome [ACS] in patients with ...
Preventing Chronic Disease | Clean Indoor Air Regulation and Incidence of Hospital Admissions for Acute Coronary Syndrome in...
Laws and regulations prohibiting smoking in public areas and workplaces can reduce rates of acute myocardial infarction. ... Secondhand smoke is a risk factor for coronary heart disease. ... Table 1. Change in Rate of Acute Coronary Syndrome Hospital ... We obtained hospital admission data for acute coronary syndrome (ACS) and acute myocardial infarction from all acute care ... Figure 1. Age-adjusted rates of hospital admissions for acute coronary syndrome, by sex, 2000-2008. Data were obtained from the ...
WHO EMRO | Acute coronary syndrome: factors predicting smoking cessation | Volume 26 issue 3 | EMHJ volume 26 2020
Acute coronary syndrome among patients with chest pain: prevalence, incidence and risk factors. Int J Cardiol. 2016 Jul 1;214: ... Keywords: acute coronary syndrome, clinical trial, predictive factors, smoking cessation, Tunisia. Citation: Abroug H; El ... Rocha V, Guerra M, Lemos M, Maciel J, Williams G. Motivation to quit smoking after acute coronary syndrome. Acta Med Port. 2017 ... Aims: To assess smoking cessation rates at 24 weeks among patients with acute coronary syndrome. Group A had begun nicotine ...
Prehospital misdiagnosis of acute cerebral disease for acute coronary syndrome: a retrospective study. - International...
Prehospital misdiagnosis of acute cerebral disease for acute coronary syndrome: a retrospective study.. ... Prehospital misdiagnosis of acute cerebral disease for acute coronary syndrome: a retrospective study. ... Prehospital misdiagnosis of acute cerebral disease for acute coronary syndrome: a retrospective study. ... In cerebrovascular accidents symptoms, laboratory results and electrocardiogram (ECG) changes can mimic acute coronary syndrome ...
Mechanisms of acute coronary syndromes and their implications for therapy
Platelet Indices in Patients with Acute Coronary Syndrome
Platelets play a central role in the pathogenesis of acute coronary syndromes (ACS) and high MPV has been associated to more ... Platelet Indices in Patients with Acute Coronary Syndrome () Silvia Cristina Costa1, Carmen Guilherme de Matos Vinagre1,2, Ana ... Platelets play a central role in the pathogenesis of acute coronary syndromes (ACS) and high MPV has been associated to more ... Costa, S. , Vinagre, C. , Chacra, A. and Azevedo, M. (2015) Platelet Indices in Patients with Acute Coronary Syndrome. Journal ...
Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial ...
... acute coronary syndrome or those with a provisional diagnosis of acute coronary syndrome and one or more of previous coronary ... Conclusions In intermediate risk patients with acute chest pain and suspected acute coronary syndrome, early CT coronary ... to the emergency department with suspected acute coronary syndrome or with a provisional diagnosis of acute coronary syndrome. ... population of patients with suspected acute coronary syndrome or those with a provisional diagnosis of acute coronary syndrome ...
Acute coronary syndrome Information | Mount Sinai - New York
... recovery and follow-up care for Acute coronary syndrome. ... Learn about Acute coronary syndrome, find a doctor, ... Acute coronary syndrome. Heart attack - ACS; Myocardial infarction - ACS; MI - ACS; Acute MI - ACS; ST elevation myocardial ... Heart attack and unstable angina are both acute coronary syndromes (ACS).. Causes. A fatty substance called plaque can build up ... Acute coronary syndrome is a term for a group of conditions that suddenly stop or severely reduce blood from flowing to the ...
Non-ST Elevation Acute Coronary Syndromes - MDCalc
Official ACEP 2006 NSTEMI guideline summary for evaluation and management of patients suffering from non-ST elevation acute ... In adult patients with suspected acute non-ST-elevation acute coronary syndrome who are determined to be low risk based on ... In adult patients with suspected acute non-ST-elevation acute coronary syndrome, conventional troponin testing at 0 and 3 hours ... Non-ST Elevation Acute Coronary Syndromes. (beta). Official guideline from the American College of Emergency Physicians. ...
Acute Coronary Syndrome | AdventHealth Medical Group | AdventHealth
Risk of Acute Coronary Syndrome dramatically increases after mRNA jabs, new Study finds - David Icke
Risk of Acute Coronary Syndrome dramatically increases after mRNA jabs, new Study finds. ... Read More: Risk of Acute Coronary Syndrome dramatically increases after mRNA Covid Injections, a new Study finds ... to a study presented at the American Heart Association Scientific Sessions 2021 the risk of developing acute coronary syndrome ...
Video: Rapid Diagnostic Algorithms for Acute Coronary Syndromes
Efficacy and Safety of Intracoronary versus Intravenous Administration of Tirofiban during Percutaneous Coronary Intervention...
Finding Acute Coronary Syndromes (ACS) With Serial Troponin Testing for Rapid Assessment of Cardiac Ischemic Symptoms - Full...
Acute Coronary Syndrome. Syndrome. Disease. Pathologic Processes. Myocardial Ischemia. Heart Diseases. Cardiovascular Diseases ... Finding Acute Coronary Syndromes (ACS) With Serial Troponin Testing for Rapid Assessment of Cardiac Ischemic Symptoms (FAST- ... Acute Coronary Syndromes. Non ST-Segment Elevation Myocardial Infarction. ST-Segment Elevation Myocardial Infarction. Unstable ... The subject must present to the Emergency Department with symptoms consistent with acute coronary syndromes (e.g., chest ...
Acute Coronary Syndrome Symptoms - High Blood Pressure Symptoms | Causes | Diet | Treatment
Detail symptoms of acute coronary Syndrome ACS Angina Nono Q Wave MI and Myocardial infarction ... Acute Coronary Syndrome Symptoms. Detail symptoms of acute coronary Syndrome ACS Angina Nono Q Wave MI and Myocardial ... High Blood Pressure Symptoms , Causes , Diet , Treatment , Heart Diseases , Acute Coronary Syndrome Symptoms ... o Thought to be due to coronary vasospasm. * Elderly persons and those with diabetes may have particularly subtle presentations ...
Prasugrel for the treatment of acute coronary syndromes with percutaneous coronary intervention: NICE technology appraisal...
Prasugrel for the treatment of acute coronary syndromes with percutaneous coronary intervention: NICE technology appraisal ... Prasugrel for the treatment of acute coronary syndromes with percutaneous coronary intervention: NICE technology appraisal ... Prasugrel for the treatment of acute coronary syndromes with percutaneous coronary intervention: NICE technology appraisal ...
Acute Coronary Syndrome and Heart Attack : Medical Animation
... which is the main symptom of acute coronary syndrome. Other symptoms of acute coronary syndrome include shortness of breath, ... If you have acute coronary syndrome, blood flow through your coronary arteries is severely reduced or completely blocked. One ... If youve had a heart attack or have other types of acute coronary syndrome, your doctor may prescribe oxygen therapy to get ... MEDICAL ANIMATION TRANSCRIPT: If you have acute coronary syndrome, you have one or more conditions caused by a blockage of ...
2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment...
Clinical Twisters: Choosing a heparin for acute coronary syndrome
Sleep disturbance after acute coronary syndrome: A longitudinal study over 12 months - Docwire News
Home Cardiology Sleep disturbance after acute coronary syndrome: A longitudinal study over 12 months ... Sleep disturbance after acute coronary syndrome: A longitudinal study over 12 months. By ... BACKGROUND: Sleep disturbance has been associated with poor prognosis in patients with acute coronary syndrome (ACS). This ... with ACS admitted to a tertiary hospital to undergo acute coronary intervention. Sleep disturbance was interviewer-assessed at ...
Ticagrelor Compared to Clopidogrel in Acute Coronary Syndrome and Stable Coronary Artery Disease - TheNNTTheNNT
Ticagrelor Compared to Clopidogrel in Acute Coronary Syndrome and Stable Coronary Artery Disease Does not reduce heart attacks ... Study Population: Patients with acute coronary syndrome (ACS) who underwent percutaneous coronary intervention (PCI) ... clopidogrel in Japanese, Korean and Taiwanese patients with acute coronary syndrome -- randomized, double-blind, phase III ... non-ST-elevation acute coronary syndrome and ST-elevation myocardial infarction and patients who undergo percutaneous coronary ...
Prehospital aspirin administration for acute coronary syndrome (ACS) in the USA: an EMS quality assessment using the NEMSIS...
Prehospital aspirin administration for acute coronary syndrome (ACS) in the USA: an EMS quality assessment using the NEMSIS ... Prehospital aspirin administration for acute coronary syndrome (ACS) in the USA: an EMS quality assessment using the NEMSIS ... Introduction National practice guidelines recommend early aspirin administration to reduce mortality in acute coronary syndrome ...
Article | Reducing patient delay with symptoms of acute coronary syndrome: a research protocol for a systematic review of...
Reducing patient delay with symptoms of acute coronary syndrome: a research protocol for a systematic review of previous ... Reducing patient delay with symptoms of acute coronary syndrome: a research protocol for a systematic review of previous ... INTRODUCTION: Delay to presentation with symptoms of acute coronary syndrome (ACS) is common meaning many fail to achieve ... Development of Interventions to reduce patient delay with symptoms of Acute Coronary Syndrome: identifying optimal content and ...
Comparison of Diagnostic Criteria to Detect Undiagnosed Diabetes in Acute Coronary Syndrome Patients with Admission...
Acute Coronary Syndrome, Fasting blood sugar, Admission plasma sugar, Oral glucose tolerance test, Glycated haemoglobin, ... Admission hyperglycemia adversely influences the outcome of acute coronary syndrome patients. The study was conducted to ... Conclusion: Admission hyperglycaemia does not diagnose diabetes reliably in a stressful condition like acute coronary syndrome ... Comparison of Diagnostic Criteria to Detect Undiagnosed Diabetes in Acute Coronary Syndrome Patients with Admission ...
Outcomes in Women and Minorities After Everolimus-Eluting Stent Implantation | Acute Coronary Syndromes | JN Learning | AMA Ed...
Dimensional structure and correlates of posttraumatic stress symptoms following suspected acute coronary syndrome | Academic...
... the first examination of the latent structure of PTSD symptoms after suspected ACS in 399 adults in the REactions to Acute Care ... and some have suggested that PTSD triggered by acute coronary syndrome (ACS) may differ from PTSD due to prototypical traumas. ... Dimensional structure and correlates of posttraumatic stress symptoms following suspected acute coronary syndrome. Sumner, ... and some have suggested that PTSD triggered by acute coronary syndrome (ACS) may differ from PTSD due to prototypical traumas. ...
MyocardialPercutaneousAngiographyClinicalArteriesStable Coronary ArteryDiseaseUnstable anginaManagement of acute coronaryAntiplatelet TherapySymptoms of acute coronaryComputed tomographyElevationElectrocardiogramAmong patients with acuteArtery bypass graft surgeryDiagnosisDischargeCardiac careInterventionHeart failureRiskCardiologyMethodsRevascularizationMortalityOutcomeChronicObservationalHospitalizationAdverse outcomesChestAdmissionMedscapeDiabetesOutcomes in patientsClopidogrelPrognosisIntravascular
Myocardial23
- Acute coronary syndrome (ACS) refers to a spectrum of clinical presentations ranging from those for ST-segment elevation myocardial infarction (STEMI) to presentations found in non-ST-segment elevation myocardial infarction (NSTEMI) or in unstable angina. (medscape.com)
- Laws and regulations prohibiting smoking in public areas and workplaces can reduce rates of acute myocardial infarction. (cdc.gov)
- We obtained hospital admission data for acute coronary syndrome (ACS) and acute myocardial infarction from all acute care hospitals serving Kanawha County, West Virginia, for 2000 through 2008. (cdc.gov)
- Platelets play a central role in the pathogenesis of acute coronary syndromes (ACS) and high MPV has been associated to more reactive platelets and regarded as an independent risk factor for myocardial infarction. (scirp.org)
- Khode, V., Sindhur, J., Kanbur, D., Ruikar, K. and Nallulwar, S. (2012) Mean Platelet Volume and Other Platelet Volume Indices in Patients with Stable Coronary Artery Disease and Acute Myocardial Infarction: A Case Control Study. (scirp.org)
- In adult patients without evidence of ST-elevation acute coronary syndrome, other risk-stratification tools, such as Thrombolysis in Myocardial Infarction ( TIMI ), can be used to predict a rate of 30-day major adverse cardiac event. (mdcalc.com)
- Do not routinely use further diagnostic testing (coronary computed tomography [CT] angiography, stress testing, myocardial perfusion imaging) prior to discharge in low-risk patients in whom acute myocardial infarction has been ruled out to reduce 30-day major adverse cardiac events. (mdcalc.com)
- For patients presenting with clinical suspicion of Acute Coronary Syndromes (ACS), high sensitivity-cardiac Troponin I (hs-cTnI) provides improved diagnostic accuracy for ACS (including Acute Myocardial Infarction (AMI) and/or Unstable Angina (UA)) within the first two (2) hours after emergency department presentation when compared to currently available troponin assays. (clinicaltrials.gov)
- MI is caused by rupture of an atherosclerotic plaque in a coronary artery, leading to platelet aggregation and thrombus formation to an extent that oxygenation of the myocardial tissue is completely interrupted (i.e., total occlusion), with the occurrence of some degree of myocardial necrosis. (clinicaltrials.gov)
- The 2016 ACC/AHA Guideline "Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease," makes a class IIa recommendation that ticagrelor is preferential to clopidogrel for both non-ST-elevation acute coronary syndrome and ST-elevation myocardial infarction and patients who undergo percutaneous coronary intervention. (thennt.com)
- The PRECISE-DAPT, PARIS, and DAPT (bleeding component) risk scores were applied in the TRILOGY ACS population to evaluate their performance to predict adjudicated non-coronary artery bypass grafting-related GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries) severe/life-threatening/moderate and TIMI (Thrombolysis in Myocardial Infarction) major/minor bleeding with time-dependent c-indices. (duke.edu)
- Acute coronary syndrome (ACS) is a clinical entity that is characterized by the rupture of a vulnerable atheromatous plaque existing in a coronary vessel, accompanied by the formation of an intracoronary thrombus triggered by the processes of platelet aggregation, activation of the coagulation cascade, and thrombosis, all of which result in different degrees of myocardial ischemia. (anejo.eu)
- Due to the obstruction of coronary flow and the decrease in oxygen supply, the onset of unstable angina or acute myocardial infarction can be observed. (anejo.eu)
- Patients were divided into three groups based on final diagnosis of acute myocardial infarction or unstable angina and all others with noncardiac chest pain. (cdc.gov)
- There were no differences in time to ECG for women compared with men with acute myocardial infarction or unstable angina, but women received an ECG significantly slower than men for noncardiac chest pain. (cdc.gov)
- Was the death specific clinical conditions (i.e. acute myocardial infarction, coronary of this patient expected? (who.int)
- 2] A prediction model that and transparency of such risk adjustment models, and to widen uses a `history of coronary heart disease' as a risk factor to predict discussion on the strengths and limitations of risk adjustment models death from an acute myocardial infarction (AMI) is always going based on service claims data. (who.int)
- History of coronary heart disease (a condition caused by narrowing of the arteries that supply blood to the heart) included a reported history of coronary heart disease, myocardial infarction, or angina pectoris. (cdc.gov)
- For instance, lipid profiles are well acknowledged to be associated with the risk of coronary artery disease (CAD) and myocardial infarction (MI) [ 1 ]. (biomedcentral.com)
- Tako-tsubo-like left ventricular dysfunction': a clinical entity mimicking acute myocardial infarction with a favorable prognosis. (stanfordhealthcare.org)
- Acute hypoxia causes an increase in heart rate, myocardial contractility, and cardiac output. (marinemedicalsociety.in)
- Optional ACS mode provides higher sensitivity 12SL analysis for the detection of acute coronary syndrome in patients suspected of acute myocardial infarction or ischemia. (georgiananesthesia.com)
- Atherosclerotic cardiovascular disease (ASCVD) involves the buildup of cholesterol plaque in arteries and includes acute coronary syndrome, peripheral arterial disease, and events such as myocardial infarction and stroke. (kingfisherbeerusa.com)
Percutaneous13
- Yang, A., Pizulli, L. and Lüderitz, B. (2006) Mean Platelet Volume as Marker of Restenosis after Percutaneous Transluminal Coronary Angioplasty in Patients with Stable and Unstable Angina Pectoris. (scirp.org)
- Guan W, Lu H, Yang K. Choosing between ticagrelor and clopidogrel following percutaneous coronary intervention: A systematic review and Meta-Analysis (2007-2017). (thennt.com)
- Dual antiplatelet therapy with compared to aspirin alone after percutaneous coronary intervention modestly reduces nonfatal events like heart attack and stroke. (thennt.com)
- The systematic review summarized here 3 included 11 trials and 5 observational studies that in aggregate enrolled 25,805 subjects with acute coronary syndrome undergoing percutaneous coronary intervention as well as those with stable CAD. (thennt.com)
- Angioplasty (almost always with stenting), also called percutaneous coronary intervention (PCI), is a procedure that should be performed within 90 minutes of arriving at the hospital. (adam.com)
- BACKGROUND: Longitudinal bleeding risk scores have been validated in patients treated with dual antiplatelet therapy (DAPT) following percutaneous coronary intervention. (duke.edu)
- CONCLUSIONS: Among medically managed patients with ACS treated with DAPT, the performances of the PRECISE-DAPT, PARIS, and DAPT (bleeding component) scores were reasonable and similar to their performances in the derivation percutaneous coronary intervention populations. (duke.edu)
- Trans-radial approach versus trans-femoral approach in patients with acute coronary syndrome undergoing percutaneous coronary intervention: An updated meta-analysis of randomized controlled trials. (bvsalud.org)
- Trans-radial approach (TRA) is recommended over trans-femoral approach (TFA) in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). (bvsalud.org)
- Figure 4: Successful percutaneous coronary intervention for chronic total occlusion is associated with reduced angina frequency. (nature.com)
- Annual operator volume among patients treated using percutaneous coronary interventions with rotational atherectomy and procedural outcomes : analysis based on a large national registry. (krakow.pl)
- Clinical outcomes in patients undergoing complex, high-risk percutaneous coronary intervention and haemodynamic support with intra-aortic balloon versus Impella pump : real-life single-centre preliminary results. (krakow.pl)
- Comparison of safety and effectiveness between the right and left radial artery approach in percutaneous coronary intervention. (krakow.pl)
Angiography13
- Coronary CT angiography (CCTA) may be an option in those with a low-to-modest clinical likelihood of unstable angina as a normal scan excludes coronary artery disease (CAD): It has a high negative predictive value (NPV) to rule out ACS (by excluding CAD) and a positive outcome in patients presenting to the emergency department with a low-to-intermediate pretest probability for ACS and a normal CCTA. (medscape.com)
- Coronary angiography may be done right away or when you are more stable. (medlineplus.gov)
- Objectives To establish if the use of early computed tomography (CT) coronary angiography improves one year clinical outcomes in patients presenting to the emergency department with acute chest pain and at intermediate risk of acute coronary syndrome and subsequent clinical events. (bmj.com)
- Interventions Early CT coronary angiography and standard of care compared with standard of care only. (bmj.com)
- Results Between 23 March 2015 and 27 June 2019, 1748 participants (mean age 62 years (standard deviation 13), 64% men, mean global registry of acute coronary events (GRACE) score 115 (standard deviation 35)) were randomised to receive early CT coronary angiography (n=877) or standard of care only (n=871). (bmj.com)
- Median time from randomisation to CT coronary angiography was 4.2 (interquartile range 1.6-21.6) hours. (bmj.com)
- The primary endpoint occurred in 51 (5.8%) participants randomised to CT coronary angiography and 53 (6.1%) participants who received standard of care only (adjusted hazard ratio 0.91 (95% confidence interval 0.62 to 1.35), P=0.65). (bmj.com)
- Invasive coronary angiography was performed in 474 (54.0%) participants randomised to CT coronary angiography and 530 (60.8%) participants who received standard of care only (adjusted hazard ratio 0.81 (0.72 to 0.92), P=0.001). (bmj.com)
- Early CT coronary angiography was associated with a slightly longer time in hospital (median increase 0.21 (95% confidence interval 0.05 to 0.40) days from a median hospital stay of 2.0 to 2.2 days). (bmj.com)
- Conclusions In intermediate risk patients with acute chest pain and suspected acute coronary syndrome, early CT coronary angiography did not alter overall coronary therapeutic interventions or one year clinical outcomes, but reduced rates of invasive angiography while modestly increasing length of hospital stay. (bmj.com)
- These findings do not support the routine use of early CT coronary angiography in intermediate risk patients with acute chest pain and suspected acute coronary syndrome. (bmj.com)
- A coronary angiography test can show your doctor how well blood is moving through your heart. (mountsinai.org)
- Methods: A prospective study was conducted in patients ≥55 years old undergoing coronary angiography for an acute coronary syndrome. (elsevier.com)
Clinical6
- In adult patients without evidence of ST-elevation acute coronary syndrome, the History, electrocardiogram [ECG], Age, Risk factors, Troponin ( HEART ) score can be used as a clinical prediction instrument for risk stratification. (mdcalc.com)
- Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients with Non-ST-segment Elevation Acute Coronary Syndromes. (mdcalc.com)
- The MEDIMACS project is an academically funded, prospective, randomized, controlled and mechanistic clinical trial designed to address the effects of an active randomized intervention with the Mediterranean diet on atherosclerotic plaque vulnerability, coronary endothelial dysfunction and other mechanistic endpoints. (biomedcentral.com)
- Clinical predictors of future ischemic events in patients with acute coronary syndrome (ACS) are also risk factors for bleeding, with patients often at high-risk of both outcomes. (elsevier.com)
- Increases in CRP concentration are non-specific and should be used in conjunction with traditional clinical laboratory evaluation of acute coronary syndromes. (cdc.gov)
- includes background demographic and clinical information of the acute episode of COVID-19. (who.int)
Arteries12
- A hard substance called plaque can build up in the walls of your coronary arteries. (mountsinai.org)
- If blood moves slowly, or not at all through your coronary arteries, you have either a narrowed, or blocked artery. (mountsinai.org)
- Connected to your aorta are small arteries called coronary arteries. (smartimagebase.com)
- Blood flows from your aorta, through the coronary arteries, to supply your heart muscle with oxygen and nutrients. (smartimagebase.com)
- If you have acute coronary syndrome, blood flow through your coronary arteries is severely reduced or completely blocked. (smartimagebase.com)
- In this condition, a build-up of a fatty substance called plaque can narrow your coronary arteries. (smartimagebase.com)
- During a coronary artery dissection, the inside wall of one of your coronary arteries separates, which can block blood flow. (smartimagebase.com)
- Drugs such as nitroglycerin and morphine will relax your coronary arteries and relieve the pain of angina. (smartimagebase.com)
- CABG is a surgical procedure in which the blocked areas of the coronary arteries are bypassed with veins or artificial graft material. (smartimagebase.com)
- To perform this strenuous task, the heart muscle itself needs a plentiful supply of oxygen-rich blood, provided through a network of coronary arteries. (adam.com)
- Most heart attacks are caused by a blood clot that blocks one of the coronary arteries. (stlukes-stl.com)
- The coronary arteries bring blood and oxygen to the heart. (stlukes-stl.com)
Stable Coronary Artery1
- 16 STEMI and 12 NSTEMI, and 25 patients with stable coronary artery disease (CAD). (krakow.pl)
Disease26
- Secondhand smoke is a risk factor for coronary heart disease. (cdc.gov)
- Subsequently, other diseases and adverse effects of secondhand smoke were established, including increased risk for coronary heart disease (CHD) (2). (cdc.gov)
- Smoking is the main preventable cause of morbidity and premature death worldwide (1) and is a major and independent risk factor for coronary heart disease (CHD) (2). (who.int)
- Prehospital misdiagnosis of acute cerebral disease for acute coronary syndrome: a retrospective study. (iasp-pain.org)
- Participants Adults with suspected or a provisional diagnosis of acute coronary syndrome and one or more of previous coronary heart disease, raised levels of cardiac troponin, or abnormal electrocardiogram. (bmj.com)
- Diabetes mellitus is one of the most important risk factors of coronary artery disease. (banglajol.info)
- HIV-positive patients are increasingly being affected by non-communicable diseases such as coronary artery disease (CAD). (biomedcentral.com)
- Antiretroviral therapy (ART) treated HIV-positive patients are experiencing fewer HIV-related opportunistic infections and are increasingly being affected by the same age-associated spectrum of atherosclerotic disease, including coronary artery disease (CAD), as the general population [ 2 ]. (biomedcentral.com)
- MAIN OUTCOMES AND MEASURES: The primary end point (major coronary events)was the composite of coronary heart disease (CHD) death, MI, or urgent coronary revascularization formyocardial ischemia. (eur.nl)
- Atherosclerosis causes coronary artery disease (CAD), the most prevalent non-communicable disease in Western countries. (biomedcentral.com)
- Among adults at low risk, prevalence of coronary heart disease is low, and cardiac screening is of low predictive value. (medscape.com)
- Background: Epidemiological studies have shown a higher risk of cardiovascular mortality associated with early menopause, but the relation between menopausal age and extent of coronary artery disease after menopause is unknown. (elsevier.com)
- We assessed the relation between menopausal age and extent of coronary disease in postmenopausal women with an acute coronary syndrome. (elsevier.com)
- Both acute and long-term exposure to elevated levels of ozone in air are associated with negative health effects ranging from increased morbidity and mortality due to respiratory and cardiovascular disease (Crouse et al. (cdc.gov)
- A growing number of patients, particularly those with advanced, chronic coronary artery disease, experience symptoms of angina that are refractory to treatment with β-blockers, calcium-channel blockers, and long-acting nitrates, despite revascularization. (nature.com)
- In the United States, lipoprotein apheresis is potentially covered and can be considered for Lp(a) reduction among people with LDL≥100 mg/dL, Lp(a)≥60 mg/dL, and coronary or peripheral artery disease. (cdc.gov)
- The prevalences of awareness of all five common heart attack symptoms, as well as the appropriate response when recognizing a heart attack (unadjusted and adjusted for age, sex, race/ethnicity, level of education, history of coronary heart disease, and number of CVD risk factors) were estimated overall and by selected demographic characteristics and CVD risk factors in 2008, 2014, and 2017. (cdc.gov)
- Recent randomized controlled trials have challenged the concept that increased high density lipoprotein cholesterol (HDL-C) levels are associated with coronary artery disease (CAD) risk reduction. (biomedcentral.com)
- Coronary artery disease (CAD) is one of the leading causes of death worldwide. (who.int)
- The aim of this study was to explore the association between hepatitis C viral infection and coronary artery disease. (who.int)
- A consecutive sample of 50 patients with abnormal angiographic findings was matched with another 50 consecutive patients with normal angiographic findings regarding age, sex, and major risk factors for coronary artery disease (diabetes mellitus, hypertension and smoking). (who.int)
- The possible association between HCV positivity and extension of coronary artery disease may refer to the role of HCV in coronary artery disease pathology. (who.int)
- El Amroosy M. Association between coronary artery disease and hepatitis C virus seropositivity. (who.int)
- Objective: to assess the prevalence of pharmacological adherence in patients with coronary artery disease and to identify factors associated with adherence. (bvsalud.org)
- Method: a crosssectional, correlational study, including 198 patients with a previous diagnosis of coronary artery disease. (bvsalud.org)
- We are suspending all but the most urgent and emergent cardiac interventions, including surgery for coronary artery and valvular heart disease. (nwcdonline.com)
Unstable angina3
- Heart attack and unstable angina are both acute coronary syndromes (ACS). (medlineplus.gov)
- Acute coronary syndrome refers to a category of emergency heart conditions in which the blood supply to the heart muscle becomes suddenly obstructed - as occurs in a heart attack or when a blood clot causes chest pain called "unstable angina. (adventhealth.com)
- If you have angina when you're at rest, or frequent angina that prevents even moderate physical activity, you have unstable angina, which is the main symptom of acute coronary syndrome. (smartimagebase.com)
Management of acute coronary1
- This guideline covers the early and longer-term (rehabilitation) management of acute coronary syndromes. (bvsalud.org)
Antiplatelet Therapy1
- Long-Term Bleeding Risk Prediction with Dual Antiplatelet Therapy After Acute Coronary Syndromes Treated Without Revascularization. (duke.edu)
Symptoms of acute coronary4
- Other symptoms of acute coronary syndrome include shortness of breath, dizziness, nausea, and sweating. (smartimagebase.com)
- Seek treatment immediately if you have the symptoms of acute coronary syndrome. (smartimagebase.com)
- Farquharson B, Dombrowski SU, Pollock A, Johnston M, Treweek S, Williams B, Smith K, Dougall N, Jones C & Pringle S (2014) Reducing patient delay with symptoms of acute coronary syndrome: a research protocol for a systematic review of previous interventions to investigate which behaviour change techniques are associated with effective interventions. (stir.ac.uk)
- INTRODUCTION: Delay to presentation with symptoms of acute coronary syndrome (ACS) is common meaning many fail to achieve optimal benefit from treatments. (stir.ac.uk)
Computed tomography1
- [ 1 , 104 ] The updates place increased reliance on high-sensitivity cardiac troponin testing (hs-cTn) for diagnosis, embrace coronary computed tomography (CT) imaging to rule out lower-risk patients, as well as highlight the need for personalized antiplatelet regimens, systems of care, and quality improvement. (medscape.com)
Elevation7
- In late August 2020, the European Society of Cardiology (ESC) released their updated guidelines for the diagnosis and management of non ST-elevation (NSTE) acute coronary syndrome (ACS). (medscape.com)
- In adult patients with suspected acute non-ST-elevation acute coronary syndrome, conventional troponin testing at 0 and 3 hours among low-risk acute coronary syndrome patients (defined by HEART score 0 to 3) can predict an acceptable low rate of 30-day major adverse cardiac events. (mdcalc.com)
- In adult patients with suspected acute non-ST-elevation acute coronary syndrome who are determined to be low risk based on validated accelerated diagnostic pathways that include a nonischemic electrocardiogram (ECG) result and negative serial high-sensitivity troponin testing results both at presentation and at 2 hours can predict a low rate of 30-day major adverse cardiac events allowing for an accelerated discharge pathway from the emergency department. (mdcalc.com)
- Background: Little is known about the characteristics of patients who were admitted to the coronary care unit (CCU) in the 1990s with non-ST elevation acute coronary syndromes (ACS) compared with those admitted to medical and cardiology wards in hospitals in the United Kingdom (UK). (qub.ac.uk)
- The prognostic value of troponin in patients with non-ST elevation acute coronary syndromes: a meta-analysis. (medscape.com)
- Influence of comorbid conditions on one-year outcomes in non-ST-segment elevation acute coronary syndrome. (medscape.com)
- 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (dicardiology.com)
Electrocardiogram1
- In cerebrovascular accidents symptoms, laboratory results and electrocardiogram (ECG) changes can mimic acute coronary syndrome (ACS) and is subsumed as neurogenic stunned myocardium. (iasp-pain.org)
Among patients with acute1
- To assess smoking cessation rates at 24 weeks among patients with acute coronary syndrome. (who.int)
Artery bypass graft surgery1
- Performance could be further improved by using summary risk prediction scores such as the EUROSCORE II for coronary artery bypass graft surgery or the GRACE risk score for acute coronary syndrome. (who.int)
Diagnosis2
Discharge7
- Few randomized controlled trials have examined the efficacy time of smoking cessation in hospitalized patients with acute coronary syndrome, either during hospitalization or after discharge. (who.int)
- Pocock SJ et al.Predicting two-year mortality from discharge after acute coronary syndrome: An internationally-based risk score. (gpnotebook.com)
- Methods An initial prospective audit of 37 acute coronary syndrome patients admitted to Leeds General Infirmary in January 2013 assessed inpatient up-titration of bisoprolol and ramipril, discharge advice and doses at 6 weeks after discharge. (bmj.com)
- Following a collective multidisciplinary effort with education, posters and discharge advice templates, a re-audit of 34 acute coronary syndrome patients admitted from November to December 2014 assessed the impact of these interventions. (bmj.com)
- Acute coronary syndrome patients are precluded from maximum mortality benefit due to suboptimal dosing after discharge. (bmj.com)
- However, to support standardization and data comparability, it should preferably be completed 4 to 8 weeks and 6 months after hospital discharge from the acute ward or after acute il ness for individuals who have not been hospitalized. (who.int)
- In case of persistent symptoms/signs after hospital discharge or after acute il ness, it is recommended to complete the CRF at 3-month intervals, for as long as needed, or at 6 months interval, if no symptoms persist (see figure below). (who.int)
Cardiac care2
- Member of the European Society of Cardiology Working Group on Acute Cardiac Care. (amj.net.au)
- This new updated edition of the textbook continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care and addresses all those involved in intensive and acute cardiac care, not only cardiologists but also critical care specialists, emergency physicians and healthcare professionals. (harperandharley.org)
Intervention1
- METHODS: Study participants were 180 patients (mean age 59.6 years, 81.7% men) with ACS admitted to a tertiary hospital to undergo acute coronary intervention. (docwirenews.com)
Heart failure2
- Is my rate of heart failure readmissions artery bypass graft (CABG) surgery, pneumonia and acute stroke). (who.int)
- Acute coronary syndromes (ACS), acute decompensated heart failure (ADHF), and serious arrhythmias form SECTIONS 6-8. (harperandharley.org)
Risk13
- they are prognostic factors and key elements of the Global Registry of Acute Coronary Events (GRACE) risk score (superior assessment to subjective physician assessment for the occurrence of death or MI). (medscape.com)
- Last week, the Cardiology Advisor reported that according to a study presented at the American Heart Association Scientific Sessions 2021 the risk of developing acute coronary syndrome ("ACS") significantly increased in patients after receiving mRNA Covid injections. (davidicke.com)
- Dr. Rick Body, Professor of Emergency Medicine at the University of Manchester and Honorary Consultant in Emergency Medicine at Manchester University NHS Foundation Trust, describes the development and implementation of a rapid diagnostic algorithm* for acute coronary syndromes, and how it is helping to reduce unnecessary hospitalization of low-risk patients. (siemens-healthineers.com)
- This study will evaluate the ability of a high sensitivity cardiac troponin I (hs-cTnI) assay to detect and to rule-out high-risk ischemic cardiac injury in emergency room patients experiencing signs and symptoms consistent with acute coronary syndromes (ACS). (clinicaltrials.gov)
- Data from high-income countries (HICs) indicate that HIV-positive patients have different risk-factor profiles for acute coronary syndrome (ACS) as well as different cardiac manifestations of this syndrome compared to HIV-negative patients. (biomedcentral.com)
- CONCLUSIONS AND RELEVANCE: In patients who experienced an ACS event, direct inhibition of Lp-PLA2with darapladib added to optimal medical therapy and initiated within 30 days of hospitalization did not reduce the risk of major coronary events. (eur.nl)
- The results of this trial will address the key effects of dietary habits on atherosclerotic risk and will provide initial data on the complex interplay of immunological, microbiome-, proteome- and metabolome-related mechanisms by which non-pharmacological factors may impact the progression of coronary atherosclerosis after an ACS. (biomedcentral.com)
- Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. (medscape.com)
- IMSEAR at SEARO: Acute coronary syndromes: risk stratification. (who.int)
- ObjectiveTo summarize data on the prevalence/incidence, risk factors and prognosis of atrial fibrillation (AF) in patients with acute coronary syndromes (ACS).MethodsMEDLINE, Embase, and Web of Science were searched to identify all published studies providing relevant data through August 23, 2020. (ox.ac.uk)
- Acute exposure to elevated levels of PM2.5 can lead to irritation of eyes, nose, throat and lungs , and increases relative risk of acute cardiovascular events including admission to a hospital for stoke (Rajagopalan et al. (cdc.gov)
- An observational study to assesss the risk factors in acute coronary syndrome at a tertiary cate hospital. (kolkataheartdoctor.com)
- The controversy over beta blockade in the ED (early in ACS) is for patients at risk for cardiogenic shock, principally patients with acute STEMI, especially anterior STEMI. (blogspot.com)
Cardiology3
- Aim: To understand if there were systematic differences in the characteristics of patients who were admitted to UK critical care units (CCU), intermediate care environments (cardiology wards) or generalist wards (acute medical ward) in an observational study carried out in the 1990s. (qub.ac.uk)
- This analysis compares the characteristics of 860 of these patients dependent on whether they were cared for in a coronary care unit, acute medical ward or cardiology ward. (qub.ac.uk)
- This was discussed extensively during the acute coronary syndrome panel session on cardiology including Dr. Laila Abdel-Wareth of Cleveland Clinic Abu Dhabi, among others. (roche-middleeast.com)
Methods2
- The study was conducted to compare the various diagnostic methods for the detection of undiagnosed diabetes mellitus in acute coronary syndrome patients with admission hyperglycaemia in Bangladeshi population. (banglajol.info)
- METHODS AND RESULTS: TRILOGY ACS (Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes) was a double-blind, placebo-controlled randomized trial conducted from 2008 to 2012 over a median follow-up of 17.0 months in 966 sites (52 countries). (duke.edu)
Revascularization1
- How these scores apply to the population of patients with acute coronary syndrome (ACS) treated without revascularization remains unknown. (duke.edu)
Mortality3
- Introduction National practice guidelines recommend early aspirin administration to reduce mortality in acute coronary syndrome (ACS). (bmj.com)
- Objectives Suboptimal dosing of angiotensin-converting enzyme inhibitors and β-blockers limits the mortality benefit for acute coronary syndrome patients. (bmj.com)
- Due to the complex of vague sepsis syndrome definitions, unknown sources of infection and higher mortality, it is necessary to establish a reliable and effective prognostic model for sepsis. (biomedcentral.com)
Outcome1
- Admission hyperglycemia adversely influences the outcome of acute coronary syndrome patients. (banglajol.info)
Chronic3
- Comparison of acute coronary syndrome in patients receiving versus not receiving chronic dialysis (from the Global Registry of Acute Coronary Events [GRACE] Registry). (medscape.com)
- New treatment principles are emerging in current practice, such as metabolic modulation, therapeutic angiogenesis, and novel interventional techniques (coronary in-flow redistribution and approaches to chronic total occlusion). (nature.com)
- This guideline covers managing acute and chronic pancreatitis in children, young people and adults. (bvsalud.org)
Observational1
- We conducted the first examination of the latent structure of PTSD symptoms after suspected ACS in 399 adults in the REactions to Acute Care and Hospitalization (REACH) study, an observational cohort study of patients recruited from the emergency department during evaluation for ACS. (columbia.edu)
Hospitalization1
- The CRF can be administered either as part of routine fol ow up or at a specific time point to any patient in the post- acute phase of COVID-19, regardless of hospitalization. (who.int)
Adverse outcomes2
- Atrial fibrillation incidence, prevalence, predictors, and adverse outcomes in acute coronary syndromes: A pooled analysis of data from 8 million patients. (ox.ac.uk)
- IMSEAR at SEARO: Incidence of Impaired Glucose Tolerance Test in Non- Diabetic Patients of Acute Coronary Syndrome and its Adverse Outcomes. (who.int)
Chest2
- A blocked coronary artery may also cause you to feel sudden pain, discomfort, tightening, or a burning sensation in your chest called angina. (smartimagebase.com)
- Admission glycaemia and its association with acute coronary syndrome in Emergency Department patients with chest pain. (medscape.com)
Admission5
- Our objective was to describe hospital admission rates for acute coronary events, based on smoking status, diabetes status, and sex, in the presence of a long-standing (2000-2008) county clean indoor air regulation (CIAR). (cdc.gov)
- Therefore, the objective of our study was to describe hospital admission rates over time (2000-2008) for acute coronary events, by smoking status, diabetes status, and sex, in the presence of an existing county-wide clean indoor air regulation (CIAR or regulation). (cdc.gov)
- Admission hyperglycaemia does not diagnose diabetes reliably in a stressful condition like acute coronary syndrome. (banglajol.info)
- Although neither admission plasma glucose, fasting plasma glucose, nor HbA1c level were as good as oral glucose tolerance test in detecting true diabetes, but combined fasting plasma glucose & HbA1c were found to be more sensitive & specific screening tool for detecting unknown diabetes in acute coronary syndrome patients with admission hyperglycaemia. (banglajol.info)
- Conclusion: Patients with acute coronary syndrome who have IGT on admission have longer hospital stay and more complications related to acute MI. (who.int)
Medscape1
- Fast Five Quiz: Test Your Knowledge of Acute Coronary Syndrome - Medscape - Apr 26, 2017. (medscape.com)
Diabetes1
- Thiamine-responsive megaloblastic anaemia (TRMA) is a syndrome associated with megaloblastic anaemia, diabetes mellitus and sensorineural deafness, due to mutations in the SLC19A2 gene, which codes for a thiamine carrier protein. (bvsalud.org)
Outcomes in patients1
- Usefulness of elevations in serum choline and free F2)-isoprostane to predict 30-day cardiovascular outcomes in patients with acute coronary syndrome. (medscape.com)
Clopidogrel1
- Although clopidogrel is still frequently used in patients with acute coronary syndromes (ACS), its efficacy is hampered by interpatient response variability caused by genetic polymorphisms associated with clopidogrel's metabolism. (dundee.ac.uk)
Prognosis1
- BACKGROUND: Sleep disturbance has been associated with poor prognosis in patients with acute coronary syndrome (ACS). (docwirenews.com)
Intravascular1
- Intravascular imaging in acute coronary syndromes. (escardio.org)