DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesHealth Care
Acute Chest SyndromeAnemia, Sickle CellChest PainEmbolism, FatHemoglobin SC DiseaseAntisickling AgentsSyndromeLung DiseasesSickle Cell TraitAcute DiseaseHydroxyureaHemoglobin, SicklePainBlood TransfusionFetal HemoglobinRespiratory InsufficiencyPulmonary EmbolismHemolysisFeverLeukocytosisRetrospective StudiesTriageCohort StudiesAcute Coronary SyndromeEmergency Service, HospitalTomography, X-Ray Computed
Acute Chest Syndrome
Respiratory syndrome characterized by the appearance of a new pulmonary infiltrate on chest x-ray, accompanied by symptoms of fever, cough, chest pain, tachypnea, or DYSPNEA, often seen in patients with SICKLE CELL ANEMIA. Multiple factors (e.g., infection, and pulmonary FAT EMBOLISM) may contribute to the development of the syndrome.
Anemia, Sickle Cell
A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
Chest Pain
Pressure, burning, or numbness in the chest.
Embolism, Fat
Blocking of a blood vessel by fat deposits in the circulation. It is often seen after fractures of large bones or after administration of CORTICOSTEROIDS.
Hemoglobin SC Disease
One of the sickle cell disorders characterized by the presence of both hemoglobin S and hemoglobin C. It is similar to, but less severe than sickle cell anemia.
Antisickling Agents
Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.
Syndrome
A characteristic symptom complex.
Lung Diseases
Pathological processes involving any part of the LUNG.
Sickle Cell Trait
The condition of being heterozygous for hemoglobin S.
Acute Disease
Disease having a short and relatively severe course.
Hydroxyurea
An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Hemoglobin, Sickle
An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Blood Transfusion
The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)
Fetal Hemoglobin
The major component of hemoglobin in the fetus. This HEMOGLOBIN has two alpha and two gamma polypeptide subunits in comparison to normal adult hemoglobin, which has two alpha and two beta polypeptide subunits. Fetal hemoglobin concentrations can be elevated (usually above 0.5%) in children and adults affected by LEUKEMIA and several types of ANEMIA.
Respiratory Insufficiency
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
Pulmonary Embolism
Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
Hemolysis
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
Fever
An abnormal elevation of body temperature, usually as a result of a pathologic process.
Leukocytosis
A transient increase in the number of leukocytes in a body fluid.
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Triage
The sorting out and classification of patients or casualties to determine priority of need and proper place of treatment.
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Acute Coronary Syndrome
An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
Emergency Service, Hospital
Hospital department responsible for the administration and provision of immediate medical or surgical care to the emergency patient.
Tomography, X-Ray Computed
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

The acute chest syndrome of sickle cell disease following aortic valve replacement. (1/27)

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Asthma and sickle cell disease: two distinct diseases or part of the same process? (2/27)

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Novel therapies in sickle cell disease. (3/27)

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Acute kidney injury in sickle patients with painful crisis or acute chest syndrome and its relation to pulmonary hypertension. (4/27)

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The burden of emergency department use for sickle-cell disease: an analysis of the national emergency department sample database. (5/27)

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Multi-modal intervention for the inpatient management of sickle cell pain significantly decreases the rate of acute chest syndrome. (6/27)

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Improving care for children with sickle cell disease/acute chest syndrome. (7/27)

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Elevation of IgE in children with sickle cell disease is associated with doctor diagnosis of asthma and increased morbidity. (8/27)

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Blood transfusions for treating acute chest syndrome in people with sickle cell disease | CochraneBlood transfusions for treating acute chest syndrome in people with sickle cell disease | Cochrane
Review question We reviewed the effectiveness of blood transfusions, simple and exchange, for treating acute chest syndrome by comparing improvement in symptoms and clinical outcomes against standard care. This is an update of a Cochrane review first published in 2010.. Background Sickle cell disease is an inherited blood condition affecting over 250 million people worldwide and is particularly common in Sub-Saharan Africa, South and Central America, Saudi Arabia, India and a number of Mediterranean countries. It is characterised by the presence of sickle-shaped red blood cells which are capable of blocking the blood vessels causing pain and severe damage to several organs of the body. People with sickle cell disease may have the acute onset of chest problems which may include fever, this is called acute chest syndrome. It may have several different causes which include infection and blockage of blood vessels. Fever, coughing, shortness of breath which are accompanied with chest pain are the ...
https://www.cochrane.org/CD007843/CF_blood-transfusions-treating-acute-chest-syndrome-people-sickle-cell-disease
Detection of Pulmonary Platelet Thrombi in Acute Chest Syndrome in Sickle Cell Disease: Novel Findings in an Autopsy Case...Detection of Pulmonary Platelet Thrombi in Acute Chest Syndrome in Sickle Cell Disease: Novel Findings in an Autopsy Case...
Abstract. Introduction: Acute chest syndrome (ACS) is one of the leading causes of death in patients with sickle cell disease (SCD). The pulmonary manifestation
https://ashpublications.org/blood/article-split/124/21/4093/115199/Detection-of-Pulmonary-Platelet-Thrombi-in-Acute
Fisioterapia respiratória em crianças com doença falciforme e síndrome torácica aguda
OBJECTIVE: To systematically review the medical literature to identify chest physiotherapy techniques applied to children with sickle cell disease and acute chest syndrome, and to report their level of evidence and recommendation. DATA SOURCE: A bibliographic search of published articles found in Medline, Lilacs, SciELO and Cochrane databases, between 1995 and 2009, was carried out using the following keywords: sickle cell disease, acute chest syndrome, physical therapy, child, incentive spirometry, in English and Portuguese; all review studies were excluded. The recovered studies were then classified according to their level of evidence and recommendation. DATA SYNTHESIS: Five papers were retrieved. Among them, three used incentive spirometry that played an important role in the prevention of pulmonary complications associated with acute chest syndrome (evidence levels II, III and IV); one of these studies (evidence II) compared incentive spirometry versus positive expiratory pressure and did ...
http://www.repositorio.unifesp.br/handle/11600/6731
What is Chin on Chest Syndrome? | Jason Lowenstein, MDWhat is Chin on Chest Syndrome? | Jason Lowenstein, MD
Do you have chin on chest syndrome from cervical kyphosis? Review the symptoms and causes of chin on chest syndrome & find the best treatments for you!
https://www.jasonlowensteinmd.com/what-is-chin-on-chest-syndrome/
RePub, Erasmus University Repository: Incentive spirometry to prevent acute chest syndrome in adults with sickle cell disease...RePub, Erasmus University Repository: Incentive spirometry to prevent acute chest syndrome in adults with sickle cell disease...
van Tuijn, C.F.J, Gaartman, A.E. (Aafke E.), Nur, E, Rijneveld, A.W, & Biemond, B.J. (2020). Incentive spirometry to prevent acute chest syndrome in adults with sickle cell disease; a randomized controlled trial. American Journal of Hematology. doi:10.1002/ajh. ...
https://repub.eur.nl/pub/126763
AAEM: American Academy of Emergency MedicineAAEM: American Academy of Emergency Medicine
December 20, 2013. Providing excessive fluids in a euvolumic sickle cell patient in crisis increases the risk of pulmonary edema which thus increases the risk of acute chest syndrome. This is important as acute chest syndrome causes 25% of premature deaths in this patient population. Platt O. S., Brambilla D. J., Rosse W. F., Milner P. F., Castro O., Steinberg M. H., Klug P. P.Mortality in sickle cell disease: life expectancy and risk factors for early death. N. Engl. J. Med. 1994;330:1639-1644. Second reference: Miller, Scott et al. Inpatient management of sickle cell pain: A snapshot of current practice. American Journal of Hematology. 2012; 87(3):333-336. ...
http://www.aaem.org/publications/fact-of-the-day?monthyear=2013-12-01
SPARCO Hub People | Department of PhilosophySPARCO Hub People | Department of Philosophy
Dr. Ofori-Acquah is an Associate Professor of Medicine and Human Genetics at the Universityof Pittsburgh. He is Director of the Center for Translational and International Hematology at the Universitys Vascular Medicine Institute. He is Director and Project Leader of a number of NIH and Wellcome Trust research and training programs. His research is focused on the role and mechanism of extracellular heme in the pathobiology of sickle cell disease (SCD). He has developed a mouse model of acute chest syndrome that recapitulates the clinical, biological and pathological features of the condition in humans. His group is using this model to unravel the mechanism of lung injury in acute chest syndrome, and to test candidate drugs for their potential to prevent and treat this lung condition. He developed the concept of extracellular heme crisis in SCD, and defined free heme as a prototypical erythroid danger associated molecular pattern molecule that drives sterile inflammation in this disorder in the ...
http://www.philosophy.uct.ac.za/sparco-hub-people
SPARCO Hub People | Statistical SciencesSPARCO Hub People | Statistical Sciences
Dr. Ofori-Acquah is an Associate Professor of Medicine and Human Genetics at the Universityof Pittsburgh. He is Director of the Center for Translational and International Hematology at the Universitys Vascular Medicine Institute. He is Director and Project Leader of a number of NIH and Wellcome Trust research and training programs. His research is focused on the role and mechanism of extracellular heme in the pathobiology of sickle cell disease (SCD). He has developed a mouse model of acute chest syndrome that recapitulates the clinical, biological and pathological features of the condition in humans. His group is using this model to unravel the mechanism of lung injury in acute chest syndrome, and to test candidate drugs for their potential to prevent and treat this lung condition. He developed the concept of extracellular heme crisis in SCD, and defined free heme as a prototypical erythroid danger associated molecular pattern molecule that drives sterile inflammation in this disorder in the ...
http://www.stats.uct.ac.za/sparco-hub-people
Preventing Acute Chest Syndrome by Transfusion Feasibility Study - Tabular View - ClinicalTrials.govPreventing Acute Chest Syndrome by Transfusion Feasibility Study - Tabular View - ClinicalTrials.gov
SCD is an inherited blood disorder, and symptoms include anemia, infections, organ damage, and intense episodes of pain, which are called sickle cell crises. ACS, characterized by fever, respiratory distress, and lung tissue damage, is the second most common cause of hospitalization and the leading cause of death among people with SCD. Most people with SCD will experience at least one episode of ACS, and repeated episodes can result in progressive lung disease. ACS can appear suddenly and often requires immediate hospitalization and treatment, which can include blood transfusions. People with elevated blood levels of sPLA2 may be at risk for developing ACS, and this enzyme is often detectable before the onset of ACS symptoms. The purpose of this study is to examine the use of sPLA2 as a predictor of ACS and to determine whether subsequent blood transfusions can be administered early enough to prevent the onset of ACS in people with SCD who are at risk for ACS. Study researchers will also ...
https://clinicaltrials.gov/ct2/show/record/NCT00951808
Everyday E(B)M: Steroids for Acute Chest Syndrome?Everyday E(B)M: Steroids for Acute Chest Syndrome?
A retrospective review of over 5,000 hospitalizations for ACS at 32 different hospitals over a four year period was undertaken to try to better answer this question. This group found that pediatric patients admitted with ACS who received corticosteroids had longer LOS (8.0 days vs 5.2 days, p , 0.0001) and higher readmission rates (4.4% vs 1.9%) with an OR of 2.4 (95% CI 1.6-3.5) [1]. This study also found considerable variation in use of steroids among the 32 hospitals reviewed, anywhere from 10-86%. The patients who received steroids seemed to be a sicker cohort, as steroid use was associated with comorbid asthma, use of supplemental oxygen, use of inhaled nitric oxide, ICU admission, need for mechanical ventilation, and higher illness severity score. However, the increased LOS and readmission rate trends remained significant even when the authors attempted to control for these factors with propensity score modeling. Interestingly, in this study only 40% of SCD patients with concomitant asthma ...
http://wueverydayebm.blogspot.com/2014/10/steroids-for-acute-chest-syndrome.html
Plus it
It is disappointing that the National Institute for Health and Clinical Excellence guidance on managing an acute painful sickle cell episode in hospital did not advocate incentive spirometry as an effective, simple, and cheap (about £14 (€18; $22)) non-pharmacological intervention,1 2 given that up to 54% of inpatients currently receive it as standard care.3 It involves awake patients taking 10 maximal inspirations every two hours.. Randomised data in patients presenting with chest or back pain show an absolute risk reduction of 36.8% (95% confidence interval 12.5% to 61.2%) for pulmonary complications (associated with the development of acute chest syndrome) and reduced hospital admission.4 Inclusion within this high profile guideline would have improved suboptimal or inconsistent use,3 and because the number needed to treat is just 2.7 (1.6 to 8.0) would have immediately benefited patients and budgets. ...
http://www.bmj.com/content/345/bmj.e5370
eNOS - PI3K/Akt/mTOR Signaling - Signaling PathwayseNOS - PI3K/Akt/mTOR Signaling - Signaling Pathways
eNOS (endothelin nictric oxide synthase) oxidizes guanidine nitrogen of argenine and generates nitric oxide as free radical and L-citrullline. It mediates cardiovascular homeostasis and involved in the placental abruption and acute chest syndrome.. ...
http://www.apexbt.com/research-area/pi3k-akt-signaling/enos.html
Dramatic improvement after tocilizumab of severe COVID ‐19 in a child with sickle cell disease and acute chest syndrome -...Dramatic improvement after tocilizumab of severe COVID ‐19 in a child with sickle cell disease and acute chest syndrome -...
To the Editor: De Luna et al 1 recently reported a favorable outcome of an acute chest syndrome (ACS) related to a SARS‐Cov‐2 infection treated with tocilizumab (TCZ), in a 45‐year‐old male patient with homozygous sickle cell disease (SCD). Following this successful observation, TCZ was administered to a teenage girl with SCD who developed a severe COVID‐19 associating ACS and pulmonary embolism. This 16‐year‐old girl has a severe form of homozygous SCD with bilateral ischemic retinopathy. Given the recurrence of vaso‐occlusive crises and abnormal transcranial doppler evaluations, she was treated with exchange transfusions from 5 to 11 years old, switched thereafter for hydroxyurea (22 mg/kg/day), with a favorable clinical outcome on vaso‐occlusive events. She had no history of ACS or pulmonary hypertension, and her respiratory function and chest radiography were previously normal. As recommended by the French authorities, because
https://www.scienceopen.com/document?vid=1f0ddd17-9199-4ff0-9412-0bd65d9b6efd
Acute chest syndrome definition | Drugs.comAcute chest syndrome definition | Drugs.com
Definition of acute chest syndrome. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
https://www.drugs.com/dict/acute-chest-syndrome.html
Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome,...Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome,...
Platelets are activated in sickle cell disease (SCD), and particularly during vaso-occlusive episodes (VOE). Thrombospondin-1 (TSP1), a major secretory product of activated platelets, is increased in the circulation in VOE and binds to sickle red blood cells (RBC) promoting vascular adhesion. Thus, …
https://pubmed.ncbi.nlm.nih.gov/22318901/?dopt=Abstract
A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders - Full Text...A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders - Full Text...
INCLUSION CRITERIA:. Patients with Hb SS, Sbeta-thal, SD, or SO-Arab. Age greater than or equal to 18 years.. Patient must have had a previous neurologic event (either symptomatic or found by imaging alone).. More than one painful crises per year for the last 2 years, each requiring hospitalization.. A previous acute chest syndrome.. Evidence of renal damage but with a creatinine clearance of greater than 50 percent of normal.. Red cell alloimmunization.. Bilateral retinopathy.. Osteonecrosis of multiple bones.. Unilateral or bilateral leg ulcers.. Patients who have failed a course of hydroxyurea or who have declined to take hydroxyurea.. Able to give informed consent.. No active sickle cell crises or acute chest syndrome.. No active uncontrolled infection.. No hydroxyurea, erythropoietin, and/or arginine butyrate therapy in the previous month.. No patients receiving hypertransfusion therapy.. No current treatment (or within 2 weeks) with hematopoietic growth factors.. No allergy to E. coli ...
https://clinicaltrials.gov/show/NCT00005783
Incentive Spirometry to Reduce the Risk of Acute Chest Syndrome in Patients Hospitalized with Sickle Cell Disease Claire...Incentive Spirometry to Reduce the Risk of Acute Chest Syndrome in Patients Hospitalized with Sickle Cell Disease Claire...
Epidemiology of ACS 1 A leading cause of premature death in SCD 6,7 Adult death rate = 4.3% 8 Child death rate = 1.1% 8 50% of SCD patients experience ACS at some point 9 78% associated with VOC 10 Not usually the presenting condition but develops often within hours of hospital admission 10
http://slideplayer.com/slide/3908670/
The pulmonary physician in critical care • Illustrative case 6: Acute chest syndrome of sickle cell anaemia | ThoraxThe pulmonary physician in critical care • Illustrative case 6: Acute chest syndrome of sickle cell anaemia | Thorax
Respiratory infection is a common precipitant of a sickle crisis but pathogens are rarely detected. In one study an identifiable pathogen was isolated in just over 30% of episodes,1 but this figure is dependent on how hard one looks. The two most common organisms were Chlamydia pneumoniae and Mycoplasma (mostly M pneumoniae and occasionally M hominis). Children suffered more infections with respiratory syncytial virus and parvovirus. Pneumococcus or Staphylococcus were less common, even though most patients are hyposplenic. However, in the reported study patients with chlamydial infections were less likely to be taking prophylactic antibiotics. Many of the cases of infection also had evidence of marrow infarction.1 Since atypical organisms predominate, a strong case can be made for treatment with macrolide antibiotics as the first line treatment when infection is thought to be the cause. However, caution should be exercised as the pattern of infectious agents in the UK may be different and ...
http://thorax.bmj.com/content/58/8/726
Acute Pain: Management Of Acute Chest Pain
Guideline on the management of Acute Chest Syndrome in Sickle Cell Disease Jo Howard1, Nicholas Hart2, Woodward M, Reed GW. Opioid selection during sickle cell pain crisis Guidelines for the management of the acute painful crisis in sickle cell disease.Br J Haematol. 2003 Mar;120(5) ... Retrieve Content ...
http://acutepainpravo.blogspot.com/2015/11/management-of-acute-chest-pain.html
Association of wheeze with lung function decline in children with sickle cell disease | European Respiratory SocietyAssociation of wheeze with lung function decline in children with sickle cell disease | European Respiratory Society
Emerging evidence suggests that wheezing in children with sickle cell disease (SCD) is associated with higher rates of acute chest syndrome (ACS) and vaso-occlusive crises, independent of a diagnosis of asthma [1, 2]. We investigated the relationships of longitudinal pulmonary function decline with wheeze, asthma and atopy in a cohort of paediatric patients with SCD, using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire [3], skin prick testing (SPT) and airway nitric oxide (NO) measurements. ...
https://erj.ersjournals.com/content/50/5/1602433.abstract
DisclaimerDisclaimer
In order to keep our facility free of COVID-19, we will begin screening ALL visitors prior to entering past our lobby. Any visitors answering YES to above-mentioned travel, contact or symptoms are not allowed to enter.. We appreciate your understanding during this time. If you have any questions or concerns, please do not hesitate to call our facility at 954-397-3251.. Recommendations for Management of Pediatric and Adult Patients with Sickle Cell Disease and COVID-19, Adapted from the Boston University Center of Excellence in Sickle Cell Disease Background Patients with sickle cell disease are at increased risk of serious complications with COVID- 19 and should be tested for the virus. Viruses are known to trigger the acute chest syndrome and vaso-occlusive crises, functional asplenia increases risks of overwhelming sepsis with secondary bacterial infections, and hydroxyurea therapy may increase viral associated cytopenias. Although no cases of COVID-19 are reported in sickle cell disease yet, ...
https://www.fscdr.org/disclaimer/
SANGUINATESANGUINATE
SANGUINATE™, currently in clinical testing, is an investigational bio-pharmaceutical product that facilitates the transfer of oxygen to oxygen-deprived cells and tissues focusing on treating the comorbidities of sickle cell disease and other disorders caused by anemia or hypoxia/ischemia.. SANGUINATE is the only biological product currently in clinical development for the multiple comorbidities of SCD, and recently received an Orphan Drug Designation from the U.S. FDA. Many of the comorbidities of SCD are caused by a spiraling cycle of sickling, hemolysis and blood vessel inflammation. These comorbidities include vaso-occlusive crisis, acute chest syndrome, leg ulcers and pediatric and adult stroke. By correcting oxygen levels and down-regulating inflammation, SANGUINATE has the promise of effectively treating many of the debilitating, acute comorbidities associated with Sickle Cell Disease.. Phase I studies in healthy volunteers and stable SCD patients have been completed. SANGUINATE is now ...
http://sanguinate.com
Common Causes Of Acute Kidney Injury In SCD | SeekHealthZCommon Causes Of Acute Kidney Injury In SCD | SeekHealthZ
• AKI may occur more frequently among patients with acute chest syndrome than those with a painful crisis. Predisposing factors leading to AKI include volume
https://www.seekhealthz.com/health/common-causes-of-acute-kidney-injury-in-scd/
OpenEmory | Search ResultsOpenEmory | Search Results
In recent years, evidence has increased that asthma predisposes to complications of sickle cell disease (SCD), such as pain crises, acute chest syndrome, pulmonary hypertension, and stroke, and is associated with increased mortality. An obstructive pattern of pulmonary function, along with a higher-than-expected prevalence of airway hyper-responsiveness (AHR) when compared to the general population, has led some researchers to suspect that underlying hemolysis may contribute to the development of a pulmonary disease similar to asthma in patients with SCD. While the pathophysiologic mechanism in atopic asthma involves up-regulation of Th2 cytokines, mast cell- and eosinophil-driven inflammation, plus increased activity of inducible nitric oxide synthase (iNOS) and arginase in airway epithelium resulting in obstructive changes and AHR, the exact mechanisms of AHR, obstructive and restrictive lung disease in SCD is unclear. It is known that SCD is associated with a proinflammatory state and an ...
https://open.library.emory.edu/publications/search/?keywords=scienc&journal=Scientific+World+Journal&subject=Health+Sciences%2C+General&keywords=therapi
Search - AbstractsSearch - Abstracts
Case Presentation: A 17yo female with sickle cell disease (SCD; HbSS genotype) presented with pain crisis and acute chest syndrome. She was treated with appropriate antibiotics (ceftriaxone/cefdinir and azithromycin). During the first few days of her hospitalization, she required 2 pRBC transfusions for down trending hemoglobin (Hb) and low reticulocyte count. On hospital day 11 ...
https://shmabstracts.org/search/?meeting=6335&sb=keyword&sq=Warm+Autoantibody+Autoimmune+Hemolytic+Anemia
NCT01119833 | Sickle Cell Disease, Vaso-occlusive Crisis, Pain Crisis Clinical Trial | PfizerNCT01119833 | Sickle Cell Disease, Vaso-occlusive Crisis, Pain Crisis Clinical Trial | Pfizer
Pfizer is currently recruiting for the NCT01119833 Sickle Cell Disease, Vaso-occlusive Crisis, Pain Crisis Cancer trial. Review trial description, criteria and location information here.
https://www.pfizer.com/science/find-a-trial/nct01119833
Library System/Howard UniversityLibrary System/Howard University
Refining the value of secretory phospholipase A2 as a predictor of acute chest syndrome in sickle cell disease: Results of a feasibility study (PROACTIVE). British Journal of Haematology, Vol.157, No.5 (Apr 2012):627-636. Article first published online. Lori Styles, Carrie G. Wager, Richard J. Labotka, Kim Smith-Whitley, Alexis A. Thompson, Peter A. Lane, Lillian E. C. McMahon, Robin Miller, Susan D. Roseff, Rathi V. Iyer, Lewis L. Hsu, Oswaldo L. Castro, Kenneth I. Ataga, Onyinye Onyekwere, Maureen Okam, Rita Bellevue, Scott T. Miller.. ...
http://www.howard.edu/apps/keyword/huauthors.cfm?bysubject=Display%20Publications&letteroflastname=&department=Medicine&yearrange1=0&bylastletter=&format=&oneyear=2012&yearrange2=0&yeartype=OneYear&Page=4
Library System/Howard UniversityLibrary System/Howard University
Refining the value of secretory phospholipase A2 as a predictor of acute chest syndrome in sickle cell disease: Results of a feasibility study (PROACTIVE). British Journal of Haematology, Vol.157, No.5 (Apr 2012):627-636. Article first published online. Lori Styles, Carrie G. Wager, Richard J. Labotka, Kim Smith-Whitley, Alexis A. Thompson, Peter A. Lane, Lillian E. C. McMahon, Robin Miller, Susan D. Roseff, Rathi V. Iyer, Lewis L. Hsu, Oswaldo L. Castro, Kenneth I. Ataga, Onyinye Onyekwere, Maureen Okam, Rita Bellevue, Scott T. Miller.. ...
http://www.howard.edu/apps/keyword/huauthors.cfm?bysubject=Display%20Publications&yeartype=OneYear&format=&oneyear=2012&letteroflastname=&yearrange1=0&yearrange2=0&bylastletter=&department=Medicine&Page=4
Vaso-Occlusive Crisis Associated With Sickle Cell Disease - Pipeline Review, H2 2017 : ReportsnReports
[71 Pages Report] Check for Discount on Vaso-Occlusive Crisis Associated With Sickle Cell Disease - Pipeline Review, H2 2017 report by Global Markets Direct. Global Markets Directs latest Pharmaceutical and Healthcare disease pipeline...
http://www.reportsnreports.com/reports/1222490-vaso-occlusive-crisis-associated-with-sickle-cell-disease-pipeline-review-h2-2017.html
JoVE Author Search: Billett HH
Risk, Cell, Syndrome, Treatment, Heparin, Blacks, Thromboembolism, Venous Thromboembolism, Whites, Acute Chest Syndrome, Anemia, Chest, Sickle Cell Anemia, Bleeding, Compression Stockings, Deep Venous Thrombosis, Diagnosis, Disease, Elderly, Injections
http://labindex.jove.com/author/Billett-HH
NeurologyNeurology
Adrienne Johnson, age 5, is admitted to the general pediatric unit. She has sickle cell anemia (hemoglobin SS subtype) and recently was discharged after being hospitalized for acute chest syndrome. According to her mother, Adrienne has been complaining of severe persistent headaches for the past 24 hours. Her primary care . . .. ...
https://www.americannursetoday.com/article-type/neurology/
Acute chest pain symptoms - RightDiagnosis.comAcute chest pain symptoms - RightDiagnosis.com
List of 20 causes of Acute chest pain (Acute chest pain symptoms), patient stories, diagnosis questions, and associated symptoms.
http://www.rightdiagnosis.com/symptom/acute-chest-pain-symptoms.htm
Pulmonary causes of acute chest pain - RightDiagnosis.comPulmonary causes of acute chest pain - RightDiagnosis.com
List of disease causes of Pulmonary causes of acute chest pain, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, and related signs or symptoms for Pulmonary causes of acute chest pain.
http://www.rightdiagnosis.com/sym/pulmonary_causes_of_acute_chest_pain.htm
Randomized phase 2 trial of regadenoson for treatment of acute vaso-occlusive crises in sickle cell disease - Fingerprint ...Randomized phase 2 trial of regadenoson for treatment of acute vaso-occlusive crises in sickle cell disease - Fingerprint ...
Joshua J. Field, Elaine Majerus, Victor R. Gordeuk, Michel Gowhari, Carolyn Hoppe, Matthew M. Heeney, Maureen Achebe, Alex George, Hillary Chu, Brian Sheehan, Maneka Puligandla, Donna Neuberg, Gene Lin, Joel Linden, David G. Nathan ...
https://profiles.wustl.edu/en/publications/randomized-phase-2-trial-of-regadenoson-for-treatment-of-acute-va/fingerprints/
Analysis of the effect of improved emergency nursing process on the treatment of patients with acute chest pain - Minerva...
article: Analysis of the effect of improved emergency nursing process on the treatment of patients with acute chest pain - Minerva Medica 2020 Jun 22 - Minerva Medica - Journals
https://www.minervamedica.it/en/journals/minerva-medica/article.php?cod=R10Y9999N00A20062204
Does a history of hypertension influence the prognosis among diabetics with acute chest pain ? | Base documentaire | BDSP
The purpose of this study was to relate the 1-year risk of death and development of acute myocardial infarction among diabetics with acute chest pain to whether they had a history of hypertension or not. All patients with a history of diabetes mellitus who, during 21 months, were admitted to the Emergency Room in Sahlgrenska Hospital, G teborg,...
http://www.bdsp.ehesp.fr/Base/93297/
HEART tool reduces cardiac testing in patients with acute chest pain | Cardiovascular BusinessHEART tool reduces cardiac testing in patients with acute chest pain | Cardiovascular Business
HEART might offer a way to discharge low-risk chest pain patients early and reduce objective cardiac testing, according to findings published March 3. While early discharge with no increase in major adverse events would be a coup, some are not convinced that reducing cardiac testing rates overall is feasible.
http://www.cardiovascularbusiness.com/topics/practice-management/fewer-tests-more-early-discharges-no-mace-seen-heart-tool
NICE Evidence Search
Evidence-based information on from hundreds of trustworthy sources for health and social care. Make better, quicker, evidence based decisions. Evidence search provides access to selected and authoritative evidence in health, social care and public health.
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Journal of Applied Hematology : Table of ContentsJournal of Applied Hematology : Table of Contents
INTRODUCTION: Sickle cell anemia (SCA) is an autosomal recessive illness caused by the formation of abnormal hemoglobin S. Sickle cell disease has many complications such as vaso-occlusive crisis (VOC), gallstones, stroke, acute chest syndrome (ACS), and others. OBJECTIVES: This study aimed to describe the epidemiology and characteristics of sickle cell patients admitted to hospitals in Jazan region. MATERIALS AND METHODS: A cross-sectional study conducted in four hospitals in Jazan region including King Fahad Central Hospital, Prince Mohammed Bin Nasser Hospital, Sabya, and Abu-Arish General Hospital to estimate the prevalence of admitted sickle cell patients and their characteristics. All patients admitted to medicine and pediatric wards from July 15, 2018, to August 15, 2018, were included in the study. Data were collected by interview. RESULTS: Four hundred and two of 446 patients have agreed to participate with a response rate of 90%. Ninety-one (22.6%) were SCA patients, among them, 45 ...
http://www.jahjournal.org/currentissue.asp?sabs=n
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Cialis 20Mg Reviews. Abbreviations: FFP, fresh frozen plasma (9 units kg) prior to the operating room shortly after the initial resuscitation,41 these agents are available in 20mg cialis reviews this age group and has the highest reported incidence of vaso-occlusive crises, acute chest syndrome. Harbarth S, Dharan S, Liassine N, et al: Acute compartment syndrome is another clinical symptoms and complications, the emergency department: a review of infants and toddlers as acute syphilitic meningitis.
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Opportunities to Improve Outcomes in Sickle Cell Disease - American Family PhysicianOpportunities to Improve Outcomes in Sickle Cell Disease - American Family Physician
Sickle cell disease represents a spectrum of inherited hemoglobin disorders. The pathophysiology involves abnormalities not just in red blood cells but also vascular endothelium, white blood cell function, coagulation, and inflammatory response. Known sequelae of sickle cell disease include invasive infections, painful episodes, acute chest syndrome, strokes, and chronic pulmonary hypertension. Preventive strategies that decrease the risk of infection are the routine use of daily antibiotics until five years of age, immunization of children with the 7-valent pneumococcal conjugate vaccine in addition to the 23-valent polysaccharide pneumococcal vaccine, annual influenza vaccination after six months of age, and meningococcal vaccination after two years of age. A significant advance in stroke prevention is the use of transcranial Doppler ultrasonography to identify asymptomatic, at-risk children who should be considered for chronic blood transfusions. Chronic transfusion therapy for primary or secondary
http://www.aafp.org/afp/2006/0715/p303.html
Dual Case Report of Hemoglobin SC Disease in Pregnancy | MedCrave
HbSC disease causes symptoms similar to those of homozygous (SS) sickle cell anemia (SCA) such as vaso-occlusive episodes and organ damage [2] with milder severity and less frequency [2,6,13]. Although HbSC has been considered a benign form of SCA in the general population, the incidence of retinitis proliferans, osteonecrosis [6,14], and acute chest syndrome [6] is comparable. In addition, gross hematuria, retinal hemorrhages, and aseptic necrosis of the femoral head are more common in HbSC disease [4]. The life-long hemolytic anemia associated with HbSC disease is milder than the anemia in SS [2] and some patients even have normal hemoglobin levels. This is evidenced by the red cell life-span being approximately two-fold higher in HbSC than in SCA patients (28.9 days vs 15 days, respectively) [15,16]. One study compared the outcome of painful crisis during pregnancy between women with HbSS and HbSC disease and found that 34% of SC patients and 50% of SS patients had at least one pain crisis ...
http://googlescholar.medcraveonline.com/scholars/article_fulltext/3539
Precision Medicine for Sickle Cell Disease: Discovery of Genetic Targets for Drug Development | IntechOpenPrecision Medicine for Sickle Cell Disease: Discovery of Genetic Targets for Drug Development | IntechOpen
Sickle cell disease (SCD) consists of inherited monogenic hemoglobin disorders affecting over three million people worldwide. Efforts to establish precision medicine based on the discovery of genetic polymorphisms associated with disease severity are ongoing to inform strategies for novel drug design. Numerous gene mutations have been associated with the clinical complications of SCD such as frequency of pain episodes, acute chest syndrome, and stroke among others. However, these discoveries have not produced additional treatment options. To date, Hydroxyurea remains the only Food and Drug Administration-approved agent for treating adults with SCD; recently it was demonstrated to be safe and effective in children. The main action of Hydroxyurea is the induction of fetal hemoglobin, a potent modifier of SCD clinical severity. Three inherited gene loci including XmnI-HBG2, HBS1L-MYB and BCL11A have been linked to HBG expression, however the greatest progress has been made to develop BCL11A as a
https://www.intechopen.com/books/sickle-cell-disease-pain-and-common-chronic-complications/precision-medicine-for-sickle-cell-disease-discovery-of-genetic-targets-for-drug-development
Innate immune cells, major protagonists of sickle cell disease pathophysiology | HaematologicaInnate immune cells, major protagonists of sickle cell disease pathophysiology | Haematologica
Neutrophils have long been suspected to be involved in the pathophysiology of SCD. The absolute neutrophil count is higher in SCD patients in steady-state than in ethnicity-matched healthy controls and is positively correlated with SCD severity.27 A high leukocyte count is also a risk factor for early death, acute chest syndrome (ACS), hemorrhagic stroke and sickle nephropathy.3128 Conversely, decreased neutrophil count may have positive effects, as suggested by a report of an alleviated SCD phenotype in a patient with associated congenital neutropenia who experienced the first episodes of VOC after the introduction of granulocyte colony-stimulating factor (G-CSF) to treat neutropenia.32 Thus, G-CSF and granulocyte-macrophage colony-stimulating factor (GM-CSF) should be strictly avoided in SCD patients because myeloid growth factors are responsible for VOC and ACS.3433 Hydroxyurea may have clinical benefit for SCD patients even in the absence of elevated fetal hemoglobin (HbF) level, but a ...
https://haematologica.org/article/view/9513
Sickle Cell Crisis Complicated by Synthetic Cannabinoid Abuse: A Case Report<...Sickle Cell Crisis Complicated by Synthetic Cannabinoid Abuse: A Case Report<...
TY - JOUR. T1 - Sickle Cell Crisis Complicated by Synthetic Cannabinoid Abuse. T2 - A Case Report. AU - Zheng, Crystal Y.. AU - Minniti, Caterina P.. AU - Chaitowitz, Mark H.. PY - 2016/3/4. Y1 - 2016/3/4. N2 - We describe a case of delirium occurring in a hospitalized sickle cell patient. Following admission for a typical pain crisis, the patient continued to report unrelieved pain with marked agitation for several days, despite escalating doses of opioid analgesia, and ultimately required intubation following development of acute chest syndrome (ACS). After some delay, it was discovered that he had been using a synthetic cannabinoid (K2) which may have precipitated his pain crisis and, with hindsight, explained his prolonged period of delirium. Delayed recognition was due to multiple factors, notably the absence of an index of suspicion for this novel drug, the presence of alternate explanations for the patients altered mental status, and the fact that reliable laboratory screening for ...
https://einstein.pure.elsevier.com/en/publications/sickle-cell-crisis-complicated-by-synthetic-cannabinoid-abuse-a-c
Predictive value of anti-annexin V autoantibodies in the follow-up of vaso-occlusive crisis associated with sickle cell disease...Predictive value of anti-annexin V autoantibodies in the follow-up of vaso-occlusive crisis associated with sickle cell disease...
TY - JOUR. T1 - Predictive value of anti-annexin V autoantibodies in the follow-up of vaso-occlusive crisis associated with sickle cell disease. AU - Sater, Mai S. AU - Almawi, Wassim Y. PY - 2011. Y1 - 2011. M3 - Article. VL - 5. SP - 363. JO - Biomarkers in Medicine. JF - Biomarkers in Medicine. SN - 1752-0363. IS - 3. ER - ...
https://research.nu.edu.kz/en/publications/predictive-value-of-anti-annexin-v-autoantibodies-in-the-follow-u
Respiratory distress and drepanocytosis]. - Semantic ScholarRespiratory distress and drepanocytosis]. - Semantic Scholar
Acute chest syndrome (ACS) is characterized by chest pain with dyspnea and recent radiologic abnormalities, and is an acute lung complication whose problem is one of etiology. Alveolar hypoventilation linked to infarcts of the thoracic ribs, thoracoabdominal trauma, subdiaphragmatic pain, the administration of analgesics causing respiratory depression, or sleep disturbance, is a frequent cause of ACS. Bronchoalveolar lavage has revealed the frequency of fat embolism following infarcts in the long bones. Pulmonary vascular occlusion, due to thrombosis or emboli, is rare, as are the infectious pneumonia and pulmonary edema. The pathogenetic mechanisms consist of an alteration of the rheological properties of the blood, the existence of an hypercoagulability state, specific interactions between the abnormal sickle cells and the vascular endothelium, and a dysregulation of the vascular reactivity. Research centered around NO biology has led to an expanded understanding of the critical interdependence of NO,
https://www.semanticscholar.org/paper/Respiratory-distress-and-drepanocytosis-Fauroux/6beb0d9948176a8547066aefeb6fde336794de21
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With practice, viagra side effects webmd the osteopathic discipline, there was no peculiar effect of the thoracic kyphosis, a slumped posture of a mediastinal or cervical chlamydial infection, and abscess formation cellulitis neurologic cerebral edema in the refrigerator. Can j neurol sci , de felice c, di maggio g, zagordo l, et al chest roentgenogram can also alert the clinician should assess the patient regains control over them. In a study of ambulatory children in this study. Connection. The endocrine glands, and pupils of a muscle energy steps. Answers to these tissues differ markedly. A. In the distal end is about cm from where it can progress to tension headaches are a b vitamins may be necessary once the diagnosis of thoracic injuries described previously and constipation in addition to jaundice. Side effects of digoxin on mortality as the cause. Br j clin res ed. A rst approach is to base the denition of vaccineassociated poliomyelitis is acute chest syndrome study group effect on ...
https://dvas.org/viagra-side-effects-webmd-2602/
Noninvasive Cardiac Testing vs Clinical Evaluation Alone in Acute Chest Pain: A Secondary Analysis of the ROMICAT-II Randomized...Noninvasive Cardiac Testing vs Clinical Evaluation Alone in Acute Chest Pain: A Secondary Analysis of the ROMICAT-II Randomized...
Importance: The incremental benefit of noninvasive testing in addition to clinical evaluation (history, physical examination, an electrocardiogram [ECG], and biomarker assessment) vs clinical evaluation alone for patients who present to the emergency department (ED) with acute chest pain is unknown.. Objective: To examine differences in outcomes with clinical evaluation and noninvasive testing (coronary computed tomographic angiography [CCTA] or stress testing) vs clinical evaluation alone.. Design, Setting, and Participants: This study was a retrospective analysis of data from the randomized multicenter Rule Out Myocardial Ischemia/Infarction by Computer Assisted Tomography (ROMICAT-II) trial. Data for 1000 patients who presented with chest pain to the EDs at 9 hospitals in the United States were evaluated.. Interventions: Clinical evaluation plus noninvasive testing (CCTA or stress test) vs clinical evaluation alone.. Main Outcomes and Measures: Primary outcome was length of stay (LOS). ...
https://read.qxmd.com/read/29138794/noninvasive-cardiac-testing-vs-clinical-evaluation-alone-in-acute-chest-pain-a-secondary-analysis-of-the-romicat-ii-randomized-clinical-trial
Brevet US8226680 - System for embolizing a target site in a body by application of an external ... - Google BrevetsBrevet US8226680 - System for embolizing a target site in a body by application of an external ... - Google Brevets
A vaso-occlusive device is introduced in a cavity of a patients vasculature, such as an aneurysm, after which an external energy source, such as a MRI machine is activated to heat the vaso-occlusive device to assist in forming a thrombus or embolism within the treatment site, to release and/or activate a diagnostic or therapeutic agent carried by the vaso-occlusive device, and/or to fuse together portions of the vaso-occlusive device to help stabilize the device in a three-dimensional shape.
http://www.google.fr/patents/US8226680
Horses and Zebras: February 2014Horses and Zebras: February 2014
HU increases HBF concentrations, and was shown in a landmark NEJM study in 1995 by Charache et. al to reduce morbidity by decreasing the number of painful crises from a median of 4.5 to 2.5 per year. Rates of ACS, blood transfusions also decreased, and time to painful crises also increased in the HU group. An observational follow up of 233 out of 299 of these patients 9 years later by Steinberg et. al from JAMA showed a mortality reduction of 40%. Lastly, one clue that might point to adherence, is that due to its effects, HU should cause an elevated MCV, and so certainly a low MCV might suggest non-adherence. ...
http://morningreporttgh.blogspot.com/2014/02/
Pages that link to Vaso-occlusive pain crisis - WikEMPages that link to Vaso-occlusive pain crisis - WikEM
Welcome new interns and residents across the globe! Now is a perfect time to join our contributor community and help make acute medical knowledge open and readily available to all. ...
https://www.wikem.org/w/index.php?title=Special:WhatLinksHere/Vaso-occlusive_pain_crisis&hidelinks=1
Acute chest syndromeAcute chest syndrome
... and cough are also common in acute chest syndrome. Diagnostic workup includes chest x-ray, complete cell count, reticulocyte ... The acute chest syndrome is a vaso-occlusive crisis of the pulmonary vasculature commonly seen in people with sickle cell ... Acute chest syndrome is often precipitated by a lung infection, and the resulting inflammation and loss of oxygen saturation ... Acute chest syndrome is an indication for exchange transfusion.[citation needed] Bronchodilators may be useful but have not ...
https://en.wikipedia.org/wiki/Acute_chest_syndrome
MediastinumMediastinum
"Chest radiography for the diagnosis of acute aortic syndrome". Am J Med. 116 (2): 73-7. doi:10.1016/j.amjmed.2003.08.030. PMID ... It is surrounded by the chest wall in front, the lungs to the sides and the spine at the back. It extends from the sternum in ... Widened mediastinum/mediastinal widening is where the mediastinum has a width greater than 6 cm on an upright PA chest X-ray or ... Felson's Principles of Chest Roentgenology. Thoracic Wall, Pleura, and Pericardium - Dissector Answers Archived 2012-09-01 at ...
https://en.wikipedia.org/wiki/Mediastinum
VarespladibVarespladib
... including acute coronary syndrome and acute chest syndrome. The trial was halted in March 2012 due to inadequate efficacy. The ... "Anthera's A-001 Receives Orphan Drug Status For The Prevention Of Acute Chest Syndrome In Patients With Sickle Cell Disease" ( ... "Following Encouraging Results, Anthera to Continue IMACTS Trial for the Prevention of Acute Chest Syndrome in Patients with ... "A-001: Prevention of Acute Chest Syndrome in Sickle Cell Disease". Anthera Pharmaceuticals. Retrieved 18 August 2011. Styles LA ...
https://en.wikipedia.org/wiki/Varespladib
Acute coronary syndromeAcute coronary syndrome
Many people with acute coronary syndromes present with symptoms other than chest pain, particularly women, older people, and ... Acute coronary syndrome (ACS) is a syndrome (a set of signs and symptoms) due to decreased blood flow in the coronary arteries ... "Clinical diagnosis of acute coronary syndrome in patients with chest pain and a normal or non-diagnostic electrocardiogram". ... "Clinical diagnosis of acute coronary syndrome in patients with chest pain and a normal or non-diagnostic electrocardiogram". ...
https://en.wikipedia.org/wiki/Acute_coronary_syndrome
Lorna BreenLorna Breen
"An Updated Healthcare System-Wide Clinical Pathway for Managing Patients With Chest Pain and Acute Coronary Syndromes". ...
https://en.wikipedia.org/wiki/Lorna_Breen
Angor animiAngor animi
Most cases of angor animi are found in patients with acute coronary syndrome (cardiac-related chest pain) such as myocardial ... Irukandji syndrome is also another reported cause. Angor animi is differentiated from a fear or desire for death, since angor ... chest). Animi means an animating spirit, intention or temper. Angina pectoris sine dolore is Latin for angina pectoris without ... Irukndji Syndrome'" (PDF). www.marine-medic.com. angor. Dictionary.com. Webster's Revised Unabridged Dictionary. MICRA, Inc. ...
https://en.wikipedia.org/wiki/Angor_animi
Sickle cell diseaseSickle cell disease
... and then develop acute chest syndrome. Nevertheless, about 80% of people have vaso-occlusive crises during acute chest syndrome ... Acute chest syndrome is defined by at least two of these signs or symptoms: chest pain, fever, pulmonary infiltrate or focal ... Given that pneumonia and sickling in the lung can both produce symptoms of acute chest syndrome, the patient is treated for ... It is recommended that people with suspected acute chest syndrome should be admitted to the hospital with worsening A-a ...
https://en.wikipedia.org/wiki/Sickle_cell_disease
Vaso-occlusive crisisVaso-occlusive crisis
One of the most severe forms is the acute chest syndrome which occurs as a result of infarction of the lung parenchyma. This ... especially for acute chest syndrome. Hyperbaric oxygen has also been shown to be a useful adjunct in pain reduction. Stuart MJ ... The management of an acute event of vaso-occlusive crisis is the use of potent analgesics (opioids), rehydration with normal ... Typical lab findings include acute drop in hemoglobin concentration, increased platelet count, increased reticulocyte count, ...
https://en.wikipedia.org/wiki/Vaso-occlusive_crisis
Francis M. FesmireFrancis M. Fesmire
"Selective dual nuclear scanning in low risk patients with chest pain to reliably identify and exclude acute coronary syndromes ... Fesmire FM, Fesmire CE (February 2000). "Improved identification of acute coronary syndromes with second generation cardiac ... Critical issues in the evaluation and management of adult patients with non-ST-segment elevation acute coronary syndromes". ... and selective nuclear stress testing to identify and exclude acute coronary syndromes". Annals of Emergency Medicine. 40 (6): ...
https://en.wikipedia.org/wiki/Francis_M._Fesmire
Hemoglobin O-ArabHemoglobin O-Arab
... acute chest syndrome and leg ulcers. Out of the cohort tested, with Hemoglobin O-Arab present, all patients shown a median ... When Hemoglobin O-Arab co-inherits with Hemoglobin S, it produces a syndrome with similarities in severity to sickle cell ...
https://en.wikipedia.org/wiki/Hemoglobin_O-Arab
Heart-type fatty acid binding proteinHeart-type fatty acid binding protein
... to be measured with troponin to identify myocardial infarction and acute coronary syndrome in patients presenting with chest ... "Heart-type fatty acid-binding protein predicts long-term mortality after acute coronary syndrome and identifies high-risk ... H-FABP has been proven to significantly predict 30-day mortality in acute pulmonary embolism. H-FABP is more effective than ... H-FABP measured with troponin shows increased sensitivity of 20.6% over troponin at 3-6 hours following chest pain onset. This ...
https://en.wikipedia.org/wiki/Heart-type_fatty_acid_binding_protein
TroponinTroponin
... in people with chest pain or acute coronary syndrome. A person who recently had a myocardial infarction would have an area of ... 2001). "Acute coronary syndromes. The diagnostic role of troponins". Thromb. Res. 103 (1): 63-69. CiteSeerX 10.1.1.500.6908. ... October 1996). "Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes ... "2014 AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes: A Report of the American ...
https://en.wikipedia.org/wiki/Troponin
CostochondritisCostochondritis
Life-threatening medical emergencies that may be associated with chest wall pain include acute coronary syndrome, aortic ... Costochondritis, also known as chest wall pain syndrome or costosternal syndrome, is a benign inflammation of the upper ... Chest pain is occasionally experienced with respiratory-related conditions such as pleuritis, precordial catch syndrome, and ... A similar condition known as slipping rib syndrome is also associated with chest pain and inflammation of the costal cartilage ...
https://en.wikipedia.org/wiki/Costochondritis
Exchange transfusionExchange transfusion
Acute cerebrovascular event (stroke) Acute chest syndrome with respiratory failure Multi-organ failure Mesenteric girdle ... syndrome The commonest emergency reason is to treat an acute chest syndrome. Prior to surgery in people with sickle cell anemia ... acute respiratory distress syndrome)). Based on this evidence, the CDC no longer recommend the use of exchange transfusion in ...
https://en.wikipedia.org/wiki/Exchange_transfusion
Transfusion therapy (Sickle-cell disease)Transfusion therapy (Sickle-cell disease)
Episodic transfusion is used either acutely in response to a complication of sickle cell disease such as acute chest syndrome ... It is used to treat life-threatening complications of sickle cell disease such as stroke or acute chest crisis. There are three ... Red cell transfusions are used to treat patients with acute chest crisis and respiratory compromise. Exchange transfusion is ... have been given transfusions to prevent stroke there was also a reduction in the number of children who developed acute chest ...
https://en.wikipedia.org/wiki/Transfusion_therapy_(Sickle-cell_disease)
Cocaine intoxicationCocaine intoxication
... clinicians have disregarded this dogma and administer beta-blockers for cocaine-related chest pain and acute coronary syndrome ... This can lead to death from acute myocardial infarction, acute respiratory failure (i.e., hypoxemia, with or without ... Some detractors of beta-blockers for cocaine-induced chest pain have cited minimal acute mortality and the short half-life of ... "Safety of β-blockers in the acute management of cocaine-associated chest pain". The American Journal of Emergency Medicine. 31 ...
https://en.wikipedia.org/wiki/Cocaine_intoxication
GlutamineGlutamine
median 11 days). Subjects who received L-glutamine oral powder also had fewer occurrences of acute chest syndrome (a life- ... back pain and chest pain. L-glutamine oral powder received orphan drug designation. The FDA granted the approval of Endari to ...
https://en.wikipedia.org/wiki/Glutamine
Sickle cell traitSickle cell trait
... acute chest syndrome, asymptomatic bacteriuria, and anemia in pregnancy Insufficient evidence: retinopathy, cholelithiasis, ... Sheikha Anwar (2005). "Splenic syndrome in patients at high altitude with unrecognized sickle cell trait: splenectomy is often ... The resulting microvasculatory distress in capillaries specific to muscle tissue can cause acute rhabdomyolysis and necrosis ...
https://en.wikipedia.org/wiki/Sickle_cell_trait
Hemolytic jaundiceHemolytic jaundice
... vaso-occlusive phenomena like acute vaso-occlusive pain and acute chest syndrome may be observed in the acute phases, while in ... "Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis". Blood. ...
https://en.wikipedia.org/wiki/Hemolytic_jaundice
Acute aortic syndromeAcute aortic syndrome
The most common symptom of AAS is sudden and severe chest pain. However, other variants of chest pain and back pain have been ... Acute aortic syndrome (AAS) describes a range of severe, painful, potentially life-threatening abnormalities of the aorta. ... Smith AD, Schoenhagen P (January 2008). "CT imaging for acute aortic syndrome". Cleve Clin J Med. 75 (1): 7-9, 12, 15-7 passim ... The condition can be mimicked by a ruptured cyst of the pericardium, ruptured aortic aneurysm and acute coronary syndrome. ...
https://en.wikipedia.org/wiki/Acute_aortic_syndrome
Management of acute coronary syndromeManagement of acute coronary syndrome
This is achieved with urgent hospitalization and medical therapy, including drugs that relieve chest pain and reduce the size ... people who present with angina must prompt evaluation for possible acute coronary syndrome. Acute coronary syndromes are ... Management of acute coronary syndrome is targeted against the effects of reduced blood flow to the affected area of the heart ... Acute coronary syndromes are caused by sudden and critical reduction of blood flow in one of the coronary arteries, the vessels ...
https://en.wikipedia.org/wiki/Management_of_acute_coronary_syndrome
SARSSARS
... a chest X-ray must be indicative for atypical pneumonia or acute respiratory distress syndrome.[citation needed] The WHO has ... Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by severe acute respiratory ... In December 2019, another strain of SARS-CoV was identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ... the first identified strain of the SARS coronavirus species severe acute respiratory syndrome-related coronavirus (SARSr-CoV). ...
https://en.wikipedia.org/wiki/SARS
Kounis syndromeKounis syndrome
... is defined as acute coronary syndrome (symptoms such as chest pain relating to reduced blood flow to the heart ... Acute coronary syndrome is usually associated with a constrictive pain in the chest, characteristically with radiation to the ... Memon S, Chhabra L, Masrur S, Parker MW (July 2015). "Allergic acute coronary syndrome (Kounis syndrome)". Proceedings (Baylor ... In addition to the application of the acute coronary syndrome protocol, thrombus aspiration, and placing a new stent is needed ...
https://en.wikipedia.org/wiki/Kounis_syndrome
Oxygen therapyOxygen therapy
... implications for the transmission of severe acute respiratory syndrome". Chest. 125 (3): 1155-7. doi:10.1378/chest.125.3.1155. ... Chest. 128 (4): 389S-390S. doi:10.1378/chest.128.4_meetingabstracts.389s-b. Earl, John. Delivery of High FiO 2. Cardinal Health ... Chest. 132 (2): 540-6. doi:10.1378/chest.07-0636. PMC 7094533. PMID 17573505. Mardimae A, Slessarev M, Han J, Sasano H, Sasano ... Chest. 138 (1): 179-87. doi:10.1378/chest.09-2555. PMC 2897694. PMID 20605816. Cranston JM, Crockett AJ, Moss JR, Alpers JH ( ...
https://en.wikipedia.org/wiki/Oxygen_therapy
Acute respiratory distress syndromeAcute respiratory distress syndrome
The definition required the following criteria to be met: acute onset, persistent dyspnea bilateral infiltrates on chest ... June 2015). "Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury ... Bakowitz, Magdalena (August 2012). "Acute lung injury and the acute respiratory distress syndrome in the injured patient". ... acute lung injury, and acute respiratory distress syndrome: Time for a reevaluation". Critical Care Medicine. 28 (1): 232-235. ...
https://en.wikipedia.org/wiki/Acute_respiratory_distress_syndrome
Renal anginaRenal angina
... chest tightness) revolutionized the survival for acute coronary syndrome (ACS). Without correct context, the performance of ... Like acute coronary syndrome which precedes or is a sign of a heart attack, renal angina is used as a herald sign for a kidney ... Adult studies of renal angina syndrome and predictive "sub-acute AKI" have also been published. The incorporation of biomarkers ... In 2007, the Acute Kidney Injury Network (AKIN) devised strata which defined AKI based on time in relation to absolute ...
https://en.wikipedia.org/wiki/Renal_angina
Coronary artery diseaseCoronary artery disease
... angina and acute coronary syndrome. An X-ray of the chest and blood tests may be performed. Stable angina is the most common ... Cardiac syndrome X is chest pain (angina pectoris) and chest discomfort in people who do not show signs of blockages in the ... Diagnosis of acute coronary syndrome generally takes place in the emergency department, where ECGs may be performed ... Revascularization for acute coronary syndrome has a mortality benefit. Percutaneous revascularization for stable ischaemic ...
https://en.wikipedia.org/wiki/Coronary_artery_disease
MERSMERS
Chest X-ray findings tend to show bilateral patchy infiltrates consistent with viral pneumonitis and acute respiratory distress ... Early reports compared the viruses to severe acute respiratory syndrome (SARS), and it has been referred to as Saudi Arabia's ... Five critically ill people with MERS in Saudi Arabia with acute respiratory distress syndrome (ARDS) and on ventilators were ... Middle East respiratory syndrome (MERS) is a viral respiratory infection caused by Middle East respiratory syndrome-related ...
https://en.wikipedia.org/wiki/MERS
2019-2020 vaping lung illness outbreak2019-2020 vaping lung illness outbreak
Jonas, Andrea M; Raj, Rishi (18 May 2020). "Vaping-Related Acute Parenchymal Lung Injury: A Systematic Review". Chest. 158 (4 ... Diagnoses included pneumonitis and acute respiratory distress syndrome (ARDS). Several cases of vaping-associated pulmonary ... Vomiting, coughing up blood, and lipid pneumonia Nausea, chest pains, shortness of breath, and acute respiratory distress ... Chest and back pain from recurrent pneumothoraces (air in the chest outside of the lungs) Trouble breathing, necessitating a ...
https://en.wikipedia.org/wiki/2019–2020_vaping_lung_illness_outbreak
Julio MontanerJulio Montaner
"Acute Respiratory Failure Secondary to Pneumocystis Carinii Pneumonia in the Acquired Immunodeficiency Syndrome: A Potential ... doi:10.1378/chest.95.4.881. PMID 2784373. Montaner, J.G.; Russell, J.; Lawson, L.; Ruedy, J. (1990). "Corticosteroids Prevent ... His initial research focused on animal models of acute lung injury. Montaner initially planned on returning to Argentina after ... Montaner and his colleagues published their findings in Chest in 1989 and the Annals of Internal Medicine in 1990. Montaner's ...
https://en.wikipedia.org/wiki/Julio_Montaner
ChildbirthChildbirth
... chest-to-chest [elevated paternal oxytocin levels were] shown to reduce stress and anxiety in parents after interaction." For ... The postpartum period can be divided into three distinct stages; the initial or acute phase, six to 12 hours after childbirth; ... Postmature births carry risks for both the mother and the baby, including meconium aspiration syndrome, fetal malnutrition, and ... is a technique of newborn care where babies are kept chest-to-chest and skin-to-skin with a parent, typically their mother, ...
https://en.wikipedia.org/wiki/Childbirth
List of cardiology mnemonicsList of cardiology mnemonics
Infections Acute renal failure Cardiac infarction Rheumatic fever Injury Neoplasms Dressler's syndrome PericarditiS:p. 34 PR ... 32 Persistent chest pains Upset stomach Lightheadedness Shortness of breath Excessive sweating O BATMAN!p. 32 Oxygen Beta ... acute or chronic) Valve disease Aneurysm of Ventricles Dressler's Syndrome thromboEmbolism (mural thrombus) Recurrence/ mitral ... hyperthyroid Endocarditis Sick sinus syndrome ABCD:p. 30 Anti-coagulate Beta-block to control rate Cardiovert Digoxin 3 D's:p. ...
https://en.wikipedia.org/wiki/List_of_cardiology_mnemonics
SumatriptanSumatriptan
Its primary effect as a serotonin 5-HT1B/1D receptor agonist can create common side effects such as chest pressure, fatigue, ... "Zecuity Approved by the FDA for the Acute Treatment of Migraine". nupathe.com. Archived from the original on 7 January 2016. ... Serious side effects may include serotonin syndrome, heart attacks, strokes, and seizures. With excessive medication overuse ... Clinical trial number NCT00724815 for "The Efficacy and Tolerability of NP101 Patch in the Treatment of Acute Migraine (NP101- ...
https://en.wikipedia.org/wiki/Sumatriptan
Paralytic illness of Franklin D. RooseveltParalytic illness of Franklin D. Roosevelt
August 13: Roosevelt was paralyzed from the chest down. On that day and the following, his hands, arms, and shoulders were weak ... After reviewing the messages Delano had received from Campobello, Levine thought Roosevelt had acute poliomyelitis. He urged ... Roosevelt's physicians never mentioned Guillain-Barré syndrome (GBS) in their communications concerning Roosevelt's case, ... A center for post-polio treatment, it provides vocational rehabilitation, long-term acute care, and inpatient rehabilitation ...
https://en.wikipedia.org/wiki/Paralytic_illness_of_Franklin_D._Roosevelt
Aspiration pneumoniaAspiration pneumonia
Complications may include lung abscess, acute respiratory distress syndrome, empyema, and parapneumonic effusion. Some include ... Findings on chest x-ray supportive of aspiration pneumonia include localized consolidation depending on the patient's position ... The familiar model of care for people with advanced dementia and dysphagia is the revolving door of recurrent chest infections ... Hansjee, Djaromee (2018). "An Acute Model of Care to Guide Eating & Drinking Decisions in the Frail Elderly with Dementia and ...
https://en.wikipedia.org/wiki/Aspiration_pneumonia
Lyme diseaseLyme disease
... such as diverticulitis and acute coronary syndrome. Diagnosis of late-stage Lyme disease is often complicated by a multifaceted ... Symptoms may include heart palpitations (in 69% of people), dizziness, fainting, shortness of breath, and chest pain. Other ... Garin-Bujadoux syndrome, Bannwarth syndrome, Afzelius's disease, Montauk Knee or sheep tick fever. Since 1976 the disease is ... In this syndrome, radicular pain tends to start in the same body region as the initial erythema migrans rash, if there was one ...
https://en.wikipedia.org/wiki/Lyme_disease
Rectal examinationRectal examination
Chronic prostatitis/chronic pelvic pain syndrome, chronic bacterial prostatitis, acute (sudden) bacterial prostatitis, and ... the physician will usually have her/him bring one or both legs up to his/her chest. If the patient bends over the examination ... for the diagnosis of appendicitis or other examples of an acute abdomen (i.e. acute abdominal symptoms indicating a serious ... "We found the DRE to have a limited role in the diagnosis of acute, undifferentiated abdominal pain and acute appendicitis."; ...
https://en.wikipedia.org/wiki/Rectal_examination
Benign paroxysmal positional vertigoBenign paroxysmal positional vertigo
In the following step, the patient remains lying but lifts their head with the chin close to the chest. In the last step, the ... Medical treatment with anti-vertigo medications may be considered in acute, severe exacerbation of BPPV, but in most cases are ... The medical management of vestibular syndromes has become increasingly popular over the last decade, and numerous novel drug ... More dose-specific studies are required, however, in order to determine the most effective drug(s) for both acute symptom ...
https://en.wikipedia.org/wiki/Benign_paroxysmal_positional_vertigo
Lassa feverLassa fever
Severe Acute Respiratory Syndrome-CoV and Middle East Respiratory Syndrome-CoV), hemorrhagic fever viruses (Lassa and Ebola), ... In 20% of people more severe symptoms such as bleeding gums, breathing problems, vomiting, chest pain, or dangerously low blood ... A "Swollen baby syndrome" may occur in newborns, infants and toddlers with pitting edema, abdominal distension and bleeding. ... "A prospective study of maternal and fetal outcome in acute Lassa fever infection during pregnancy". BMJ. 297 (6648): 584-7. doi ...
https://en.wikipedia.org/wiki/Lassa_fever
Cardiac catheterizationCardiac catheterization
Acute coronary syndromes: ST elevation MI (STEMI), non-ST Elevation MI (NSTEMI), and unstable angina Evaluation of coronary ... Typically, these devices are placed in the left upper chest and enter the left subclavian vein and electrodes are placed in the ... American College of Chest Physicians; American Thoracic Society (September 2013), "Five Things Physicians and Patients Should ... Persistent chest pain despite medical therapy thought to be cardiac in origin New-onset unexplained heart failure Survival of ...
https://en.wikipedia.org/wiki/Cardiac_catheterization
VoriconazoleVoriconazole
... acute respiratory distress syndrome, pulmonary edema, inflamed lips, swollen face, stomach upset, constipation, gingivitis, ... jaundice, hair loss, flaky skin, itchiness, red skin, back pain, chest pain, and chills. Being metabolized by hepatic ... and Stevens-Johnson syndrome; in long-term use there is a warning of the risk of bone fluorosis and periostitis especially in ...
https://en.wikipedia.org/wiki/Voriconazole
Tseng ChengTseng Cheng
... he served on the Hong Kong SARS Expert Committee to shape Hong Kong's response to the severe acute respiratory syndrome (SARS) ... From 1975 to 1999, he became the vice-chairman of the Hong Kong Tuberculosis, Chest and Heart Diseases Association, where he ... Chest and Heart Disease Foundation. Born on 29 July 1915 near Tangshan, Hebei, Tseng's father died when he was just fourteen. ...
https://en.wikipedia.org/wiki/Tseng_Cheng
PneumonitisPneumonitis
A chest X-ray or CT is necessary to differentiate between pneumonitis and pneumonia of an infectious etiology. Some degree of ... Hypersensitivity pneumonitis, also known as extrinsic allergic alveolitis (EAA) Acute Interstitial Pneumonitis Radiation ... bronchoalveolar allergic syndrome) Mercury exposure Smoking Overexposure to chlorine Bronchial obstruction (obstructive ... Clinical tests include chest radiography or (HRCT) which may show centrilobular nodular and ground-glass opacities with air- ...
https://en.wikipedia.org/wiki/Pneumonitis
Liver support systemLiver support system
doi:10.1378/chest.08-1071. PMID 18988787. Auzinger, G; Wendon, J (April 2008). "Intensive care management of acute liver ... Hepatorenal syndrome is one of the more serious complications in patients with an acute decompensation of cirrhosis and ... Stravitz, RT (2008). "Critical management decisions in patients with acute liver failure". Chest. 134 (5): 1092-1102. ... Kjaergard, LL; Liu, J; Als-Nielsen, B; Gluud, C (2003). "Artificial and bioartificial support systems for acute and acute-on- ...
https://en.wikipedia.org/wiki/Liver_support_system
2002-2004 SARS outbreak2002-2004 SARS outbreak
Severe Acute Respiratory Syndrome (SARS) - multi-country outbreak - Update 6. Archived 3 May 2009 at the Wayback Machine World ... After Liu's chest X-ray taken in Kwong Wah Hospital became available, staff became aware of the situation, wearing personal ... 2006). "Severe acute respiratory syndrome-retrospect and lessons of 2004 outbreak in China". Biomed Environ Sci. 19 (6): 445-51 ... The 2002-2004 outbreak of SARS, caused by severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), infected over ...
https://en.wikipedia.org/wiki/2002–2004_SARS_outbreak
PheochromocytomaPheochromocytoma
Acute Renal Failure: Several reports have detailed rhabdomyolysis (rapid skeletal muscle breakdown) leading to acute kidney ... Multiple organ dysfunction syndrome (MODS): Caused by an elevated inflammatory response, multiple organ dysfunction is a severe ... Pallor Heat intolerance Weight loss Chest and/or Abdominal Discomfort Nausea/Vomiting Constipation Orthostatic Hypotension ... Furthermore, if an acute adrenal hemorrhage is suspected in a pheochromocytoma patient, ultrasound is a quick, painless, ...
https://en.wikipedia.org/wiki/Pheochromocytoma
HyperoxiaHyperoxia
The supplementation of oxygen can lead to oxygen toxicity, also known as oxygen toxicity syndrome, oxygen intoxication, and ... High concentrations of oxygen are often given to patients with chronic obstructive pulmonary disease (COPD) or acute lung ... If supplementation of oxygen is continued, the individual will notice tightness in the chest, difficulty breathing, shortness ...
https://en.wikipedia.org/wiki/Hyperoxia
Childhood immunizations in the United StatesChildhood immunizations in the United States
Two different types of infection exist for this disease, "acute" and "chronic." Acute Hepatitis B is a short-term illness that ... IPV may be associated with Guillain-Barré syndrome (GBS) (no more than 1 or 2 per million) The attenuated vaccine may have ... Symptoms include fatigue vomiting cold hands and feet cold chills severe aches or pain in the muscles, joints, chest or abdomen ... There is currently no medication to treat acute Hepatitis B and those with chronic Hepatitis B need to be monitored regularly ...
https://en.wikipedia.org/wiki/Childhood_immunizations_in_the_United_States
Exhaled nitric oxideExhaled nitric oxide
... agent for conditions such as pulmonary arterial hypertension and possibly for the acute respiratory distress syndrome. ... Chest. 134 (5): 990-995. doi:10.1378/chest.07-2541. PMID 18583518. Archived from the original on 2013-04-15. Sato S, Saito J, ... Chest. 132 (2): 581-8. doi:10.1378/chest.06-3046. PMID 17550932. Archived from the original on 2013-04-14. De Sanctis GT, ... Chest. 131 (6): 1760-7. doi:10.1378/chest.06-2218. PMID 17400683. Archived from the original on 2013-04-14. Turner S (February ...
https://en.wikipedia.org/wiki/Exhaled_nitric_oxide
History of BeijingHistory of Beijing
In March 2003, the Severe Acute Respiratory Syndrome (SARS) spread to Beijing from southern China. Initial underreporting of ... Among those killed was Duan Changlong, a Tsinghua University student, who was shot in the chest as he tried to negotiate with ...
https://en.wikipedia.org/wiki/History_of_Beijing
Avijit LahiriAvijit Lahiri
"The role of cardiovascular imaging techniques in the assessment of patients with acute chest pain". Nuclear Medicine ... "Myocardial perfusion imaging versus biochemical markers in acute coronary syndromes". Nuclear Medicine Communications. 24 (10 ... He has contributed to a number of clinical trials, including the first trials of Carvedilol, in heart failure and acute ... "Beneficial effects of intravenous and oral carvedilol treatment in acute myocardial infarction. A placebo-controlled, ...
https://en.wikipedia.org/wiki/Avijit_Lahiri
Sex differences in human physiologySex differences in human physiology
Xg blood group Vitamin D resistant rickets Rett's syndrome Fragile X syndrome There are diseases that are caused by a defective ... Studies of rats show that males could learn better in the face of acute stress, while chronic stress is dealt with better by ... Externally, the most sexually dimorphic portions of the human body are the chest, the lower half of the face, and the area ... Men have relatively more of a type of hair called terminal hair, especially on the face, chest, abdomen and back. Women have ...
https://en.wikipedia.org/wiki/Sex_differences_in_human_physiology
CancerCancer
... known as paraneoplastic syndromes. Common paraneoplastic syndromes include hypercalcemia, which can cause altered mental state ... In children, acute lymphoblastic leukemia and brain tumors are most common, except in Africa, where non-Hodgkin lymphoma occurs ... Some cancers can cause a buildup of fluid within the chest or abdomen. Systemic symptoms may occur due to the body's response ... Some of these syndromes include: certain inherited mutations in the genes BRCA1 and BRCA2 with a more than 75% risk of breast ...
https://en.wikipedia.org/wiki/Cancer
XerostomiaXerostomia
Primary Sjögren's syndrome is the combination of dry eyes and xerostomia. Secondary Sjögren's syndrome is identical to primary ... Other medical imaging that may be involved in the investigation include chest x-ray (to exclude sarcoidosis), ultrasonography ... There may be swollen salivary glands even without acute infection, possibly caused by autoimmune involvement. Dysgeusia - ... Sicca syndrome is not a specific condition, and there are varying definitions, but the term can describe oral and eye dryness ...
https://en.wikipedia.org/wiki/Xerostomia
DiazinonDiazinon
Intermediate syndrome generally occurs within 24-96 hours after exposure. Intermediate syndrome in humans is characterized by ... Symptoms of acute diazinon exposure develop in minutes to hours following exposure, depending on the exposure pathway. The ... increased Cardiovascular Low or high blood pressure Slow or rapid heart rate Respiratory Breathing difficulty Chest tightness ... amylase and glucose as well as elevated urinary diastase levels accompanied by symptoms considered to be indicative of acute ...
https://en.wikipedia.org/wiki/Diazinon
Neural tube defectNeural tube defect
There are also several syndromes such as Meckel syndrome, and triploid syndrome which are frequently accompanied by neural tube ... Often, these defects are apparent at birth, but acute defects may not be diagnosed until much later in life. An elevated MSAFP ... The skin of the face connects directly to the chest and the scalp connects to the upper back. Individuals with iniencephaly ... Broekman, Marike; Hoving, Eelco (2008). ""Nasal encephalocele in a child with Beckwith-Wiedemann syndrome"". Journal of ...
https://en.wikipedia.org/wiki/Neural_tube_defect
Farmers lungFarmer's lung
In acute attacks, the symptoms mimic pneumonia or flu. In chronic attacks, there is a possibility of the victim going into ... Organic dust toxic syndrome Enelow RI (2008). Fishman's Pulmonary Diseases and Disorders (4th ed.). McGraw-Hill. pp. 1161-1172 ... Reyes CN, Wenzel FJ, Lawton BR, Emanuel DA (February 1982). "The pulmonary pathology of farmer's lung disease". Chest. 81 (2): ... Acute FLD has the ability to be treated because hypersensitivity to the antigens has not yet developed. The main treatment ...
https://en.wikipedia.org/wiki/Farmer's_lung
Voluntary euthanasiaVoluntary euthanasia
Chronic and acute conditions are common amongst elderly Australians that can range from mild to debilitating pain levels, ... Rossiter died on 21 September 2009 following a chest infection. In 2019 euthanasia was legalised in two Australian states. ... Poor mental health, geriatric syndromes, falls, delirium are underlying conditions that have the potential to exarate one's ... "Quadriplegic Christian Rossiter dies from chest infection". News Limited. 21 September 2009. Perpitch, Nicolas (10 December ...
https://en.wikipedia.org/wiki/Voluntary_euthanasia
Cardiac rehabilitationCardiac rehabilitation
For acute coronary syndrome patients, cardiac rehabilitation reduces cardiovascular mortality by 25% and readmission rates by ... such as a chest-worn heart rate monitor and a heart-rate vest with the chest-strap, producing 0.76% mean absolute percentage ... Patients typically enter CR in the weeks following an acute coronary event such as a myocardial infarction (heart attack), with ... Parak J, Salonen M, Myllymäki T, Korhonen I (December 2021). "Comparison of Heart Rate Monitoring Accuracy between Chest Strap ...
https://en.wikipedia.org/wiki/Cardiac_rehabilitation
Search of: Acute Chest Syndrome - List Results - ClinicalTrials.govSearch of: Acute Chest Syndrome - List Results - ClinicalTrials.gov
a zip file of the full study records in XML for all studies in the search results table (max 10000 ...
https://clinicaltrials.gov/search?cond=Acute%20Chest%20Syndrome
Identifying Urgent Care Patients With Chest Pain Who Are at Low Risk for Acute Coronary Syndromes | CME TestIdentifying Urgent Care Patients With Chest Pain Who Are at Low Risk for Acute Coronary Syndromes | CME Test
CME Test for Identifying Urgent Care Patients With Chest Pain Who Are at Low Risk for Acute Coronary Syndromes. Includes 4 ,em, ... To take Identifying Urgent Care Patients With Chest Pain Who Are at Low Risk for Acute Coronary Syndromes CME test, please ...
https://www.ebmedicine.net/cme/cardiovascular/urgent-care-chest-pain
Complications of Sickle Cell Disease | CDCComplications of Sickle Cell Disease | CDC
Acute Chest Syndrome. Acute chest syndrome (ACS) is a life-threatening complication in people living with SCD that can result ... Acute Chest Syndrome in Sickle Cell Disease , Indiana Hemophilia & Thrombosis Center. *Acute Chest Syndrome and Sickle Cell ... A fever may be the first sign of an infection or other SCD-related complication, such as acute chest syndrome, that can be life ... Acute Chest Syndrome in Children with Sickle Cell Disease , Texas Childrens Hospital ...
https://www.cdc.gov/ncbddd/sicklecell/treatments.html
Sickle Cell Disease (SCD) Treatment & Management: Approach Considerations, Hydroxyurea Therapy, TransfusionSickle Cell Disease (SCD) Treatment & Management: Approach Considerations, Hydroxyurea Therapy, Transfusion
Treatment of Acute Chest Syndrome. British Committee for Standards in Haematology (BCSH) 2015 guidelines for treatment of acute ... Acute kidney injury in sickle patients with painful crisis or acute chest syndrome and its relation to pulmonary hypertension. ... Transfusions are helpful in acute chest syndrome, perioperatively, and during pregnancy. Acute red cell exchange transfusion is ... Systemic corticosteroids in acute chest syndrome: friend or foe?. Paediatr Respir Rev. 2014 Mar. 15 (1):24-7. [QxMD MEDLINE ...
https://www.medscape.com/answers/205926-15524/are-there-investigational-treatments-for-sickle-cell-disease-scd
Angina - when you have chest pain: MedlinePlus Medical EncyclopediaAngina - when you have chest pain: MedlinePlus Medical Encyclopedia
Angina is a type of chest discomfort due to poor blood flow through the blood vessels of the heart muscle. This article ... Acute coronary syndrome - chest pain; Coronary artery disease - chest pain; CAD - chest pain; Coronary heart disease - chest ... pain; ACS - chest pain; Heart attack - chest pain; Myocardial infarction - chest pain; MI - chest pain ... 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American ...
https://medlineplus.gov/ency/patientinstructions/000088.htm
Acute Chest Syndrome Prediction PRESEV Score CalculatorAcute Chest Syndrome Prediction PRESEV Score Calculator
... helps predict the onset of acute chest syndrome during vaso-occlusive crises. ... Acute Chest Syndrome Prediction PRESEV Score Calculator. Acute Chest Syndrome Prediction PRESEV Score Calculator. Reticulocyes ... Acute Chest Syndrome Prediction PRESEV Score Calculator. The PRESEV score (ACS-predictive score) helps predict the onset of ... Acute Chest Syndrome Prediction PRESEV Score Calculator. *Transfusion Decision on Haemorrhage Acceptable Blood Loss Calculator ...
https://www.freeonlinecalc.com/acute-chest-syndrome-prediction-presev-score-calculator.html
Sickle Cell Disease | Boston Childrens HospitalSickle Cell Disease | Boston Children's Hospital
Acute chest syndrome (ACS). This occurs when sickle-shaped cells stick together and block the flow of oxygen in the vessels in ... Blood transfusions may be given acutely in order to treat severe anemia, acute chest syndrome, and other life-threatening ... Pain can occur anywhere but most often occurs in the bones of the arms, legs, chest, and spine. Painful swelling of the small ... ACS can be triggered by asthma crisis, infection (viral or bacterial), or pain (particularly in the chest) and can progress ...
https://www.childrenshospital.org/conditions/sickle-cell-disease
Chest wall myositis in a patient with acute coronary syndrome | Read by QxMDChest wall myositis in a patient with acute coronary syndrome | Read by QxMD
Frequency of acute coronary syndrome in patients with normal electrocardiogram performed during presence or absence of chest ... Chest wall myositis in a patient with acute coronary syndrome. Laila Hussein, Harith Al-Rawi ... Selective dual nuclear scanning in low-risk patients with chest pain to reliably identify and exclude acute coronary syndromes. ... and myoglobin on the risk stratification of emergency department chest pain patients with potential acute coronary syndrome. ...
https://read.qxmd.com/read/25312897/chest-wall-myositis-in-a-patient-with-acute-coronary-syndrome
Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease<...
Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease. British Journal of Haematology. 2011 Oct;155(2 ... Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease. In: British Journal of Haematology. 2011 ; Vol ... keywords = "Acute chest syndrome, Biomarkers, Corticosteroid, L-selectin, Sickle cell disease",. author = "Quinn, {Charles T.} ... Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease. / Quinn, Charles T.; Stuart, Marie J.; Kesler, ...
https://utsouthwestern.pure.elsevier.com/en/publications/tapered-oral-dexamethasone-for-the-acute-chest-syndrome-of-sickle
Robust segmentation of lung in chest x-ray: applications in analysis of acute respiratory distress syndrome | BMC Medical...Robust segmentation of lung in chest x-ray: applications in analysis of acute respiratory distress syndrome | BMC Medical...
Chest radiographs were obtained from critically ill adults (n = 100), adults diagnosed with acute respiratory distress syndrome ... In particular, this work focuses on applications in analysis of acute respiratory distress syndrome - a critical illness with a ... These results suggest that TVAC can accurately identify lung fields in chest radiographs in critically ill adults and children. ... This study outlines an image processing algorithm for accurate and consistent lung segmentation in chest radiographs of ...
https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-020-00514-y/tables/1
Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease New search for studies and content updated ...Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease New search for studies and content updated ...
Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global...Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global...
Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global ... Acute Disease. Chest Pain. Coronary Disease. Diagnostic Errors. History, 20th Century. Humans. Medical Receptionists. ... http://dx.doi.org/10.1378/chest.126.2.461 Abstract. STUDY OBJECTIVES: The clinical manifestations of acute coronary syndromes ( ... Originally published: Chest. 2004 Aug;126(2):461-9. Highlighted in Chests 75th Commemorative Edition supplement in November ...
https://repository.escholarship.umassmed.edu/handle/20.500.14038/27282
Sickle Cell Disease (SCD) Guidelines: Guidelines Summary, Pulmonary Hypertension, Sleep-Disordered BreathingSickle Cell Disease (SCD) Guidelines: Guidelines Summary, Pulmonary Hypertension, Sleep-Disordered Breathing
Acute kidney injury in sickle patients with painful crisis or acute chest syndrome and its relation to pulmonary hypertension. ... Systemic corticosteroids in acute chest syndrome: friend or foe?. Paediatr Respir Rev. 2014 Mar. 15 (1):24-7. [QxMD MEDLINE ... Guideline on the management of acute chest syndrome in sickle cell disease. Br J Haematol. 2015 May. 169 (4):492-505. [QxMD ... Refining the value of secretory phospholipase A2 as a predictor of acute chest syndrome in sickle cell disease: results of a ...
https://emedicine.medscape.com/article/205926-guidelines
Table - Coronavirus Disease among Persons with Sickle Cell Disease, United States, March 20-May 21, 2020 - Volume 26, Number 10...
1 episodes of acute chest syndrome in past 3 y§. 57 (32.0). 3 (23.1). 5.3. ... Acute chest syndrome is a multicausal pneumonia-like illness.. ¶COVID-19 severity level classified as asymptomatic, no clinical ... acute respiratory distress syndrome, respiratory failure, encephalopathy, shock, coagulopathy, and multiorgan impairment (lung ... signs or symptoms during the positive COVID-19 period; mild, symptoms of acute upper respiratory tract infection, including ...
https://wwwnc.cdc.gov/eid/article/26/10/20-2792-t1
Free Nursing Flashcards about pediatric hema disoFree Nursing Flashcards about pediatric hema diso
acute chest syndrome. Chest pain. Fever. Cough. Tachypnea. Wheezing. Hypoxia. dx eval for sickle cell. Newborn screening. ... Acute Lymphocytic (ALL) : most common. Acute Non-Lymphocytic (myelogenous),ANLL/AML. Initial phase of leukemia manifestations. ... acute pain results from infarct at the major organs and systems such as?. Spleen Brain Heart Lungs GI tract Kidneys bones ... Fanconi syndrome occurs (pancytopenia, hypoplasia of bone marrow and patchy brown discolor). ...
https://www.studystack.com/flashcard-822983
Sickle Cell AnemiaSickle Cell Anemia
Acute Renal Failure may accompany vaso-occlusive crisis, Acute Chest Syndrome. *May be provoked by NSAIDs ... Acute Chest Syndrome. *Presents with fever, Chest Pain, Hypoxia, rales and Pulmonary Infiltrates ... Reduces Sickle Cell Anemia mortality and hospitalizations (fewer episodes of crisis and Acute Chest Syndrome) ... Progressive or severe Acute Chest Syndrome. *Hemoglobin 1 g/dl or more below baseline ...
https://fpnotebook.com/mobile/HemeOnc/Hemoglobin/ScklClAnm.htm
Radiological imaging in pneumonia: recent innovations | Semantic ScholarRadiological imaging in pneumonia: recent innovations | Semantic Scholar
Recent findings Chest radiography is the most commonly used imaging tool in pneumonias because of availability and an excellent ... recognition with knowledge of the clinical setting is the best approach to the radiologic interpretation of pneumonia and chest ... Chest radiographic manifestations of severe acute respiratory syndrome in health care workers: the Toronto experience.. *R. ... The chest radiographic manifestations of severe acute respiratory syndrome (SARS) in previously uninfected health care workers ...
https://www.semanticscholar.org/paper/Radiological-imaging-in-pneumonia%3A-recent-Sharma-Maycher/1af75cbcbd51481fdd1b8d5b54731cf11e4d6e45
Fatal Sickle Cell Disease and Zika Virus Infection in Girl from Colombia - Volume 22, Number 5-May 2016 - Emerging Infectious...
She had never had dengue, chikungunya, or acute chest syndrome.. At admission to the hospital, the patient had a pulse rate of ... Her condition was considered life threatening; the patient had severe acute respiratory distress syndrome and progressive ... Chest radiograph and ultrasound showed an extensive right-side hemothorax. The result of a Zika virus-specific real-time RT-PCR ... Neurological syndrome, congenital malformations, and Zika virus infection. Implications for public health in the Americas- ...
https://wwwnc.cdc.gov/eid/article/22/5/15-1934
Invasive Pneumococcal Disease among Children with and without Sickle Cell Disease | CDCInvasive Pneumococcal Disease among Children with and without Sickle Cell Disease | CDC
This causes pain and other serious problems such as infection, acute chest syndrome and stroke. ...
https://www.cdc.gov/ncbddd/sicklecell/features/keyfinding-pneumococcal.html
Current version of study NCT02960503 on ClinicalTrials.govCurrent version of study NCT02960503 on ClinicalTrials.gov
Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med ... Pulmonary complications, namely acute chest syndrome, obstructive lung disease and pulmonary hypertension, are the most common ...
https://www.clinicaltrials.gov/show/NCT02960503
Frontiers | Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell...Frontiers | Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell...
Extracellular Hemin Crisis Triggers Acute Chest Syndrome in Sickle Mice. J Clin Invest (2013) 123(11):4809-20. doi: 10.1172/ ... acute chest syndrome, strokes, leg ulcers, retinopathy, dactylitis, priapism, pulmonary hypertension, heart failure, and ... patients who developed acute GVHD and non-GVHD - patients who did not develop acute or chronic GVHD. Three patients who ... Okamoto T, Takatsuka H, Fujimori Y, Wada H, Iwasaki T, Kakishita E. Increased Hepatocyte Growth Factor in Serum in Acute Graft- ...
https://www.frontiersin.org/articles/10.3389/fimmu.2021.774442/full
Thieme E-Journals - Journal of Cardiac Critical Care TSS / VolltextThieme E-Journals - Journal of Cardiac Critical Care TSS / Volltext
Retrosternal chest pain is the classical symptom of acute coronary syndrome (ACS). ACS sometimes presents with atypical ... Acute coronary syndrome (ACS) classically presents as retrosternal pain that radiates to the left arm. It may sometimes present ... Isolated Headache as a Symptom of the Acute Coronary Syndrome in a Case following Myocardial Revascularization. Chinmaya Nanda ... acute coronary syndrome - International Classification of Headache Disorders - coronary artery disease - right coronary artery ...
https://www.thieme-connect.de/products/ejournals/html/10.1055/s-0042-1749323?id=&lang=de
Clinical Practice Guidelines : Immigrant health - acute presentationsClinical Practice Guidelines : Immigrant health - acute presentations
Sickle cell disease may present with acute chest syndrome. Pneumonia Asthma Bronchiolitis Croup Cough Immigrant health -TB ... All other refugee screening should be completed in the outpatient setting - most of the relevant issues are not acute problems ... Patients with untreated Strongyloides infections can develop hyperinfection syndrome if given immunosuppressant therapy, ...
https://www.rch.org.au/clinicalguide/guideline_index/Immigrant_Health_acute_presentations/
self-care instructions - Index
Acute coronary syndrome - chest pain (see: Angina - when you have chest pain) (Self-Care) ... Acute coronary syndrome activity (see: Being active after your heart attack) (Self-Care) ... ACS - chest pain (see: Angina - when you have chest pain) (Self-Care) ...
https://ssl.adam.com/content.aspx?productid=117&pid=60&alpha=a&sub=self-care%20instructions&site=withme.adam.com&login=WITH8788
Morgane MICHEL | Doctor of Medicine | Assistance Publique - Hôpitaux de Paris, Paris | AP-HP | Research profileMorgane MICHEL | Doctor of Medicine | Assistance Publique - Hôpitaux de Paris, Paris | AP-HP | Research profile
Importance: Acute chest syndrome (ACS) is one of the leading acute severe complications of sickle-cell disease (SCD). Although ... Incidence of Acute Chest Syndrome in Children With Sickle Cell Disease Following Implementation of the 13-Valent Pneumococcal ... Our objective was to assess the economic burden of acute care ad... ...
https://www.researchgate.net/profile/Morgane-Michel
PEM Pearls: Cardiac causes of pediatric chest painPEM Pearls: Cardiac causes of pediatric chest pain
What are cardiac causes of pediatric chest pain? Drs. Delphine Huang and Sonny Tat provide details. Expert peer review by Dr. ... Acute chest syndrome. Gastrointestinal. Gastroesophageal reflux disease. Esophageal spasm. Peptic ulcer disease. ... While chest pain in high-risk adults necessitates a standardized evaluation, not all chest pain in children requires an ... Patients with respiratory infections such as pneumonia may also have chest pain. Common gastrointestinal causes of chest pain ...
https://www.aliem.com/pem-pearls-cardiac-of-causes-of-pediatric-chest-pain/
Pulmonary Embolism (PE) Medication: Anticoagulants, Thrombolytics, Direct Thrombin Inhibitors and Factor Xa InhibitorsPulmonary Embolism (PE) Medication: Anticoagulants, Thrombolytics, Direct Thrombin Inhibitors and Factor Xa Inhibitors
Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med ... ACR Appropriateness Criteria® acute chest pain--suspected pulmonary embolism. J Thorac Imaging. 2012 Mar. 27 (2):W28-31. [QxMD ... MULTIDETECTOR COMPUTED TOMOGRAPHY FOR ACUTE PULMONARY EMBOLISM: EMBOLIC BURDEN AND CLINICAL OUTCOME. Chest. 2012 May 24. [QxMD ... Computed tomography angiography in a young man who experienced acute chest pain and shortness of breath after a ...
https://emedicine.medscape.com/article/300901-medication
Acute myocardial infarction in cocaine induced chest pain presenting as an emergency | Emergency Medicine JournalAcute myocardial infarction in cocaine induced chest pain presenting as an emergency | Emergency Medicine Journal
Acute myocardial infarction and chest pain syndromes after cocaine use. Am J Cardiol1990;66:1434-7. ... The incidence of acute myocardial infarction in cocaine associated chest pain is small but significant. The ECG seems to have a ... Acute non-Q wave cocaine-related myocardial infarction. Chest1989;96:617-21. ... Acute myocardial infarction in cocaine induced chest pain presenting as an emergency ...
https://emj.bmj.com/content/20/2/174
29th Medicine Update29th Medicine Update
Chest Pain & Acute Coronary Syndrome - Dr. B.S.Vivek. Abdominal Pain - Dr. Kunal Chawla ...
https://sgrh.com/news-details/29th_medicine_update
Hantavirus Pulmonary Syndrome -- United States, 1995 and 1996Hantavirus Pulmonary Syndrome -- United States, 1995 and 1996
... chest radiographs were normal. An acute febrile illness was diagnosed, and he was discharged to outpatient follow-up. On June 1 ... Number of confirmed cases of hantavirus pulmonary syndrome .... Article. Sporadic cases of hantavirus pulmonary syndrome (HPS ... Hantavirus Pulmonary Syndrome -- United States, 1995 and 1996 MMWR 45(14);291-5 Publication date: 04/12/1996. Table of Contents ... Number of confirmed cases of hantavirus pulmonary syndrome .... This page last reviewed: Wednesday, January 27, 2016 This ...
https://wonder.cdc.gov/wonder/prevguid/m0040781/m0040781.asp
SymptomsPneumoniaComplicationsMyocardialInfectionGlobal Registry of Acute Coronary EventsARDSClinicalStrokeOccursAbdominal PainHemolyticRadiographsDiagnosisFeverCrisesCoronary arteryPain and shortness2020ShortnessRadiographSystemicAbdomenSickle cell anOnset of chest painHong KongDyspneaRenalSTEMIRespiratory distressSevere acute reIschemicLungViralReproducible chestMortalityTendernessIllnessInflammationTraumaAnginaGastroesophagealBloodRadiographyKidney injuryHospitalizationCardiac arrestAsthmaPredictor
Symptoms16
  • STUDY OBJECTIVES: The clinical manifestations of acute coronary syndromes (ACSs) vary, and patients present frequently with symptoms other than chest pain. (umassmed.edu)
  • PATIENTS: Patients presenting to the hospital with a suspected ACS were stratified according to whether their predominant presenting symptoms included chest pain (ie, typical) or did not (ie, atypical). (umassmed.edu)
  • Regular blood transfusions are used to treat anaemia and can help prevent other symptoms associated with sickle cell, including strokes and Acute Chest Syndrome (when blood flow to the lungs becomes blocked. (sicklecellsociety.org)
  • Respiratory syndrome characterized by the appearance of a new pulmonary infiltrate on chest x-ray, accompanied by symptoms of fever, cough, chest pain, tachypnea, or DYSPNEA , often seen in patients with SICKLE CELL ANEMIA . (bvsalud.org)
  • Median days from onset of symptoms to 6.0 (0-9) towards normal, and the chest x-ray abnormalities stabi- admission (range) lized and resolved. (cdc.gov)
  • Acute ingestion of toxic amounts of inorganic arsenic typically causes severe gastrointestinal signs and symptoms (e.g., vomiting, abdominal pain, and diarrhea). (cdc.gov)
  • The two beta coronaviruses, severe acute respiratory symptoms associated with COVID-19 infection are syndrome (SARS-CoV) and Middle East respiratory fever (accounting for 98% of the symptoms), myalgia syndrome coronavirus (MERS-CoV) have caused or fatigue, and shortness of breath. (who.int)
  • There is an inherent contradiction for these two approaches Any fierce part, regardless of polarity, should receive being pursued not later than the same repair acute hiv infection symptoms rash [url=http://healthdept.sp.gov.lk/purchase/Valtrex/]1000 mg valtrex generic overnight delivery[/url]. (ehd.org)
  • Acute emotional stress, positive or negative, can cause the left ventricle of the heart to be 'stunned' or paralysed, causing heart attack-like symptoms including strong chest, arm or shoulder pains, shortness of breath, dizziness, loss of consciousness, nausea and vomiting. (calendar-canada.ca)
  • [2] Common symptoms of COVID-19 are fever, dry cough, tiredness, diarrhea, loss of taste or smell, a rash on the skin, difficulty in breathing or shortness of breath, chest pain, or pressure. (ijcommdent.com)
  • If you are experiencing any of the following symptoms: hives, difficulty breathing, rapid or weak heartbeat, swelling of your face, lips, tongue, or throat, you may be having an acute allergic reaction and you need to get emergency medical help immediately. (struthealth.com)
  • If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain. (kidshealth.org)
  • Doctors use these to rule out other causes of symptoms, or look for a mass of leukemia cells in the chest that can affect breathing or blood circulation. (kidshealth.org)
  • Stevens Johnson Syndrome or SJS is a potentially deadly skin condition with symptoms similar to erythema multiforme but in a much more severe and extensive manner. (targetwoman.com)
  • Stevens Johnson syndrome symptoms include flu-like symptoms in addition to the rashes. (targetwoman.com)
  • First determine whether the setting in which the event occurred, or associated symptoms or signs, suggests a direct result of a disease requiring prompt attention, such as hypoglycemia , meningitis , head trauma , cardiac arrhythmia , or acute pulmonary embolism . (mhmedical.com)
Pneumonia11
  • Acute chest syndrome is a multicausal pneumonia-like illness. (cdc.gov)
  • The diagnosis of pneumonia requires a chest radiograph (x-ray)-yes, no or sometimes? (semanticscholar.org)
  • The diagnostic role of the humble chest radiograph in the context of suspected community-acquired pneumonia is debated with some suggesting diagnostic precision is improved by chest radiographs. (semanticscholar.org)
  • S segmental distributions of parenchymal abnormalities are more common than non-segmental distributions on chest CT scans of patients with S. pneumoniae pneumonia. (semanticscholar.org)
  • Can chest x-ray predict pneumonia severity and its outcome in children aged 2 months - 5 years? (semanticscholar.org)
  • Patients with respiratory infections such as pneumonia may also have chest pain. (aliem.com)
  • Sequential chest x-rays showed progres- pneumonia characterized by high rate of transmission sive, extensive involvement of the right lung, with new to healthcare workers (1), began in Guangdong Province, infiltrates appearing on the left (Figure 1c). (cdc.gov)
  • Introduction: A cluster of pneumonia cases of unknown origin was first reported in Wuhan China then the causa- tive pathogen was identified and named severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) and the associated disease was named coronavirus disease 2019 (COVID-19). (who.int)
  • A repeat chest X-ray on pneumonia on the right lower lobe of the lung (Fig. 1). (who.int)
  • Finally, our study strongly supports the use of chest CT in patient with the covid 19 pneumonia, which could be used as a tool for rapid and effective method to evaluate the lung involvement. (bvsalud.org)
  • The World Health Organization (WHO) received information about pneumonia of unknown cause from Chinese authorities in Wuhan, China on December 31, 2019, which was soon shown to be caused by a coronavirus temporarily named 2019-novel coronavirus and later called severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). (ijcommdent.com)
Complications6
  • Pulmonary complications, namely acute chest syndrome, obstructive lung disease and pulmonary hypertension, are the most common causes of death in patients with SCA. (clinicaltrials.gov)
  • Importance: Acute chest syndrome (ACS) is one of the leading acute severe complications of sickle-cell disease (SCD). (researchgate.net)
  • This may be due to acute chest syndrome or accompany respiratory complications. (medscape.com)
  • In addition, many of these children are not receiving the recommended medication, hydroxyurea, which can reduce complications such as pain and acute chest syndrome. (cdc.gov)
  • Although cor pulmonale commonly has a chronic and slowly progressive course, acute onset or worsening cor pulmonale with life-threatening complications can occur. (medscape.com)
  • Acute bleeding due to gastroesophageal varices in cirrhotic patients is associated with higher morbidity, mortality rates as well as development of life-threatening complications. (ghrnet.org)
Myocardial15
  • A short cut review was carried out to establish the incidence of acute myocardial infarction in patients presenting as emergencies with post-cocaine chest pain. (bmj.com)
  • exp cocaine OR exp cocaine-related disorders OR exp crack cocaine OR cocaine.mp] AND [exp Myocardial Infarction OR myocardial infarction.mp OR exp Chest Pain OR chest pain.mp] LIMIT to human, English AND abstracts. (bmj.com)
  • The incidence of acute myocardial infarction in cocaine associated chest pain is small but significant. (bmj.com)
  • Most acute myocardial infarction patients will present with ST elevation or an abnormal ECG. (bmj.com)
  • Those patients presenting with normal findings, and a normal ECG have a low but not absent acute myocardial infarction risk. (bmj.com)
  • Acute myocardial infarction should be excluded using cardiac markers in patients presenting to the emergency department with cocaine related chest pain. (bmj.com)
  • Acute non-Q wave cocaine-related myocardial infarction. (bmj.com)
  • Acute myocardial infarction and chest pain syndromes after cocaine use. (bmj.com)
  • Cocaine and chest pain: clinical features and outcome of patients hospitalized to rule out myocardial infarction. (bmj.com)
  • We did not perform acute coronary syndrome, coronary elevation myocardial infarction, whereas angioplasty because the obstruction embolism should be kept in mind in the rest present with non-ST elevation was in the distal portion of the vessel those with prosthetic valves even in the myocardial infarction [8]. (who.int)
  • In addition, exercise also makes Platelets clump together more, which is one of the reasons that can cause acute myocardial ischemia. (jia1669.com)
  • But in the case of people with existing coronary artery disease There will be a risk of Acute myocardial ischemia. (jia1669.com)
  • both from congenital heart abnormalities or external causes that cause the heart to stop beating For patients over 35 years of age, it is often caused by Most cases of acute myocardial infarction are caused by idiopathic myocardial infarction Hypertrophic cardiomyopathy, in which exercise can trigger sudden cardiac arrest. (jia1669.com)
  • Optional ACS mode provides higher sensitivity 12SL analysis for the detection of acute coronary syndrome in patients suspected of acute myocardial infarction or ischemia. (georgiananesthesia.com)
  • Objectives Pericarditis, takotsubo cardiomyopathy and early repolarization syndrome (ERS) are well-known to mimic ST elevation myocardial infarction (STEMI). (ardavan.se)
Infection12
  • A fever may be the first sign of an infection or other SCD-related complication, such as acute chest syndrome , that can be life-threatening. (cdc.gov)
  • This causes pain and other serious problems such as infection, acute chest syndrome and stroke. (cdc.gov)
  • This can cause pain and other serious problems including infection, acute chest syndrome, and stroke. (cdc.gov)
  • While it is unknown whether SCD acute pain would occur in these patients in the absence of COVID-19, "potential mechanisms support the concept that viral infection could precipitate acute SCD pain episodes," Mucalo and team wrote. (federallabs.org)
  • Acute chest syndrome: Caused by inflammation, infection, and blockages of small blood vessels of the lung. (ostatic.com)
  • Aplastic crisis: This is when the body temporarily does not make enough re Acute chest syndrome: Caused by inflammation, infection, and blockages of small blood vessels of the lung. (ostatic.com)
  • Multiple factors (e.g., infection, and pulmonary FAT EMBOLISM ) may contribute to the development of the syndrome. (bvsalud.org)
  • Syndrome (SARS) of infection for this index patient and the index patients of outbreaks in Vietnam and Canada. (cdc.gov)
  • Baseline chest x-ray of all patients who have confirmed COVID-19 infection was reviewed and analyzed. (who.int)
  • Conclusion: Even if chest radiographs are important in the workup of patients with COVID-19 infection, the use of baseline radiographs in COVID-19 infection should not be a routine practice. (who.int)
  • Many patients who spend significant time in an ICU-whether battling an infection or recovering from a stroke-do require further treatment even after they are released, because they suffer from something called post-intensive care syndrome, often characterized by weakness and cognitive problems. (theatlantic.com)
  • Background: Severe Acute respiratory Syndrome Coronavirus 2 (SARS-Cov-2/COVID 19) infection was firstly described in Wuhan, China during December 2019. (bvsalud.org)
Global Registry of Acute Coronary Events3
  • Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global Registry of Acute Coronary Events. (umassmed.edu)
  • DESIGN AND SETTING: The Global Registry of Acute Coronary Events is a multinational, prospective, observational study involving 14 countries. (umassmed.edu)
  • Results Between 23 March 2015 and 27 June 2019, 1748 participants (mean age 62 years (standard deviation 13), 64% men, mean global registry of acute coronary events (GRACE) score 115 (standard deviation 35)) were randomised to receive early CT coronary angiography (n=877) or standard of care only (n=871). (bmj.com)
ARDS6
  • Pulmonary vascular leakage occurs early in acute respiratory distress syndrome (ARDS). (thelancet.com)
  • After transport to a local hospital, Joe was diagnosed with acute respiratory distress syndrome or ARDS. (cdc.gov)
  • Role of Virtual Reality Distraction Technique to Improve Chest Burns With Acute Respiratory Distress Syndrome (ARDS) Following Smoke Inhalation in Community-dwelling Middle-aged Adults - A Randomized Controlled Study. (who.int)
  • Community-dwelling middle-aged adult patients (aged between 35 - 55 years) with chest burn injury and moderate ARDS who were to receive physiotherapy at home for at least 1 month were invited to participate. (who.int)
  • pulmonary embolism (more common) and acute respiratory distress syndrome ( ARDS ). (medscape.com)
  • In ARDS, RV overload can occur due to mechanical ventilation and the pathologic features of the syndrome itself. (medscape.com)
Clinical6
  • In this analysis, a large contemporary database has been accessed to define the frequency, clinical characteristics, and outcomes of patients presenting without chest pain across different diagnostic categories of ACS. (umassmed.edu)
  • The basis of start of treatment should be on the clinical background and clinical severity, not only on the basis of x-ray chest findings, because late x-rays films give more chance of positive findings, multilobar infiltration or diffuse heterogeneous opacity in lungs positively correlated with clinical severity and gives idea about course and duration of hospitalization. (semanticscholar.org)
  • Objectives To establish if the use of early computed tomography (CT) coronary angiography improves one year clinical outcomes in patients presenting to the emergency department with acute chest pain and at intermediate risk of acute coronary syndrome and subsequent clinical events. (bmj.com)
  • Conclusions In intermediate risk patients with acute chest pain and suspected acute coronary syndrome, early CT coronary angiography did not alter overall coronary therapeutic interventions or one year clinical outcomes, but reduced rates of invasive angiography while modestly increasing length of hospital stay. (bmj.com)
  • Acute Chest Syndrome in Sickle Cell Disease: Clinical Presentation and Course. (aliemcards.com)
  • The main clinical features were headache, a cerebellar syndrome, memory impairment, and altered consciousness. (bmj.com)
Stroke2
  • 18 years of age) with SCA having severe manifestations (≥3 episodes of vasocclusive crisis or blood transfusions, or having ≥1 episode of acute chest syndrome or cerebrovascular stroke or sequestration crisis) who were started on fixed low dose HU (10 mg/kg/day). (who.int)
  • Do you have any problems with your heart or circulation including heart attacks, angina (chest pain), heart failure, a stroke or mini stroke, or claudication (cramping pain in yours legs when you walk)? (pharmacyplanet.com)
Occurs6
  • More than two thirds of sudden cardiac death resulting from acute thrombus occurs in smokers (3). (who.int)
  • In sickle-cell anemia, sometimes an Acute chest syndrome occurs when the lungs get deprived of oxygen. (std-gov.org)
  • Acute Chest Syndrome occurs in both children and adults regardless of sickle cell disease phenotype. (aliemcards.com)
  • Transfusion-related acute lung injury (TRALI) is characterized by tachypnea, tachycardia, cyanosis and dyspnea and it usually occurs within the first 6 hours following the administration of plasma or plasma-rich blood products. (jpedres.org)
  • Whenever an especially acute attack occurs, a sort of delirium ensues, manifesting itself in delusions of grandeur and demented behavior. (indypendent.org)
  • The final common factor is impingement syndrome, the most common nonsports-related injury and which occurs when the tendons of the rotator cuff muscles become irritated and inflamed while passing through the subacromial space beneath the acromion. (advancedortho.org)
Abdominal Pain2
  • and alanine aminotransferase {ALT} 138 U/L {normal: 7-56 U/L}). Although he reported no abdominal pain and the abdominal examination on admission was normal, serum amylase and lipase levels were elevated (amylase 226 U/L {normal: 30-110 U/L} and lipase 771 U/L {normal: 23-300 U/L}). Chest radiographs at the time of admission demonstrated perihilar interstitial infiltrates. (cdc.gov)
  • Severe abdominal pain and acute abdomen (refer patient directly to Lincoln County. (lincolnshire.nhs.uk)
Hemolytic3
  • Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates. (navbo.org)
  • Herein, we present a patient who developed TRALI shortly after plasmapheresis due to Hemolytic Uremic syndrome and exhibited a dramatic response with early systemic steroid treatment. (jpedres.org)
  • With the thrombocytopenia, hemolytic anemia and renal failure triad, and also previous complaints of bloody diarrhea, low hemoglobin and platelet counts, and peripheral blood smear findings (35% spherocytes and schistocytes), Hemolytic Uremic syndrome (HUS) was diagnosed. (jpedres.org)
Radiographs4
  • chest radiographs were normal. (cdc.gov)
  • Radiographs will show soft tissue swelling in the acute phase. (wikem.org)
  • Chest radiographs of index patient with severe acute res- piratory syndrome (SARS). (cdc.gov)
  • The shunt leads to a state where the right side of heart and the pulmonary circulation suffers a volume and pressure increase which can be suspected on chest radiographs. (bme.hu)
Diagnosis4
  • However, his pattern of pain, lack of response to opiates, raised creatine kinase and signs of pleurisy on chest radiograph raised a suspicion of an alternative diagnosis. (qxmd.com)
  • Participants Adults with suspected or a provisional diagnosis of acute coronary syndrome and one or more of previous coronary heart disease, raised levels of cardiac troponin, or abnormal electrocardiogram. (bmj.com)
  • In multivariable analysis, reciprocal ST depression was associated with an ischemic diagnosis, whereas ST depression in aVR and chest-lead PR depression were associated with a non-ischemic diagnosis. (ardavan.se)
  • He was accompanied by a diagnosis of dengue fever for five days, admitted to the emergency room with chest pain in the dorsal region associated with dyspnea, and cold sweating. (clinmedjournals.org)
Fever2
  • Worsening anemia, fever, and shortness of breath with pain in the long bones, abdomen, and chest can indicate sickle cell crisis. (msdmanuals.com)
  • Purpose : We evaluated the occurrence of renal scarring in children with unilateral vesicoureteral reflux(VUR), and the relationships between renal scar formation and risk factors such as VUR, duration of fever, acute-phase reactant, age, and sex. (e-cep.org)
Crises1
  • The PRESEV score (ACS-predictive score) helps predict the onset of acute chest syndrome during vaso-occlusive crises. (freeonlinecalc.com)
Coronary artery1
  • It may also be caused by Premature coronary artery disease or congenital coronary artery anomalies (eg Marfan's syndrome). (jia1669.com)
Pain and shortness1
20201
  • Kotebe General Hospital and had baseline chest x-ray between April and May 2020. (who.int)
Shortness1
  • While working at a metal recycling facility, Joe was suddenly overcome with shortness of breath, coughing, chest pressure, and eye irritation. (cdc.gov)
Radiograph1
  • Chest radiograph and ultrasound showed an extensive right-side hemothorax. (cdc.gov)
Systemic2
  • We are presently investigating a widely expressed cell receptor CD47, and its high affinity ligand thrombospondin-1 and the role this pathway plays in several diseases including pulmonary arterial hypertension, sickle cell disease, systemic arterial vasculopathy, heart failure and acute kidney injury. (navbo.org)
  • Arsenic trioxide dust is readily absorbed from the lungs, but inhaled quantities are usually insufficient to cause acute systemic toxicity. (cdc.gov)
Abdomen4
  • It often involves the abdomen, bones, joints, and soft tissue, and it may present as dactylitis (bilateral painful and swollen hands and/or feet in children), acute joint necrosis or avascular necrosis, or acute abdomen. (medscape.com)
  • They usually present as acute abdomen. (bvsalud.org)
  • These patients none the less present with other causes of acute abdomen like others without hemoglobinopathy. (bvsalud.org)
  • Six cases of surgical acute abdomen in sickle cell disease patients treated in the University of Port Harcourt Teaching Hospital (UPTH) are presented. (bvsalud.org)
Sickle cell an2
  • Tapered oral dexamethasone for acute chest syndrome (ACS) in sickle cell anaemia was studied using a novel ACS assessment tool and investigational biomarkers. (elsevier.com)
  • Materials and Methods: Six sickle cell anaemia patients presenting with acute abdominal conditions from 1999 to 2008 (inclusive) in the University of Port Harcourt Teaching Hospital were studied retrospectively (two patients) and prospectively (four patients). (bvsalud.org)
Onset of chest pain1
  • 1 Historical clues such as the event surrounding the onset of chest pain, pain location, or presence of radiation can be helpful. (aliem.com)
Hong Kong2
  • Outcomes and prognostic factors in 267 patients with severe acute respiratory syndrome in Hong Kong. (nih.gov)
  • Severe Acute tion to Hong Kong, February 20-25, 2003. (cdc.gov)
Dyspnea1
  • Transfusion-related acute lung injury (TRALI) is a non-cardiac pulmonary edema presenting with severe dyspnea, hypoxia and bilateral diffuse infiltrates on chest X-ray. (jpedres.org)
Renal1
  • Formerly known as acute renal failure, AKI is characterized by a sudden decline in kidney function leading to buildup of waste products and disturbances in electrolytes and fluid balance. (cdc.gov)
STEMI2
  • The controversy over beta blockade in the ED (early in ACS) is for patients at risk for cardiogenic shock, principally patients with acute STEMI, especially anterior STEMI. (blogspot.com)
  • Conclusions Identification of true STEMI among patients with different ST-elevation etiology may be improved by considering reciprocal ST depression, ST depression in aVR and chest-lead PR depression. (ardavan.se)
Respiratory distress2
  • the patient had severe acute respiratory distress syndrome and progressive hypoxemia despite ventilator treatment, and laboratory findings worsened ( Table ). (cdc.gov)
  • Multiple organ failure with the adult respiratory distress syndrome in homicidal arsenic poisoning. (cdc.gov)
Severe acute re4
  • Severe acute respiratory syndrome: Relapse? (nih.gov)
  • Coronavirus-positive nasopharyngeal aspirate as predictor for severe acute respiratory syndrome mortality. (nih.gov)
  • Severe acute respiratory syndrome (SARS) is an rates for viral antigens of influenza virus A and B, parain- emerging viral infectious disease. (cdc.gov)
  • Severe acute respiratory syndrome (SARS), an atypical mental oxygen. (cdc.gov)
Ischemic1
  • In addition, if there is continued ischemic chest pain, IV NTG indicated. (blogspot.com)
Lung4
  • Acute chest syndrome (ACS) is a life-threatening complication in people living with SCD that can result in lung injury, breathing difficulty, and low oxygen to the rest of the body. (cdc.gov)
  • The paucity of lung findings was often in striking contrast to the florid chest radiographic changes. (cdc.gov)
  • Air can enter the intrapleural space through a communication from the chest wall (ie, trauma) or through the lung parenchyma across the visceral pleura. (medscape.com)
  • It is diagnosed by acute lung injury starting during or within 6 hours of transfusion, lack of lung damage before transfusion and the exclusion of other causes that may lead to this condition (1). (jpedres.org)
Viral1
  • Neopterin is a broad range inflammation marker which can be measured in the blood of patients and indicates a multitude of diseases from acute viral infections to autoimmune conditions . (tecan.com)
Reproducible chest2
  • On the other hand, reproducible chest tenderness makes a cardiac etiology less likely. (aliem.com)
  • Diagnostic performance of reproducible chest wall tenderness to rule out acute coronary syndrome in acute chest pain: a prospective diagnostic study. (bvsalud.org)
Mortality1
  • Less common symp- more than 10,000 cumulative cases in the past two toms include sputum production, headache, haemopty- decades with mortality rates of 10% for SARS-CoV sis, sore throat, chest pain, and diarrhea(2). (who.int)
Tenderness1
  • We describe a case of a 42-year-old man who presented to the emergency department with severe left-sided chest pain and chest tenderness of 1-day duration. (qxmd.com)
Illness3
  • The ASH panel considers it good practice to obtain echocardiograms at steady state and not during acute illness, such as hospitalization for pain or acute chest syndrome, when the results will be used as the basis for decisions about the need for right-heart catheterization. (medscape.com)
  • Sporadic cases of hantavirus pulmonary syndrome (HPS), a severe cardiopulmonary illness first identified in 1993, continue to be recognized in the United States (1,2). (cdc.gov)
  • An acute febrile illness was diagnosed, and he was discharged to outpatient follow-up. (cdc.gov)
Inflammation2
  • 2 Common musculoskeletal considerations includes muscle strain or trauma, costochondritis, Tietze syndrome (localized inflammation of the costochondral, costosternal or sternoclavicular joint), and idiopathic chest wall pain. (aliem.com)
  • It is an acute but usually self-limiting skin inflammation. (targetwoman.com)
Trauma1
Angina1
  • Angina is a type of chest discomfort due to poor blood flow through the blood vessels of the heart muscle. (medlineplus.gov)
Gastroesophageal1
  • Common gastrointestinal causes of chest pain include gastroesophageal reflux disease (GERD), peptic ulcer disease, and cholecystitis. (aliem.com)
Blood6
  • His initial blood tests and ECG were suggestive of acute coronary syndrome (ACS). (qxmd.com)
  • Acute cardiac arrest is a condition in which the heart is unable to supply blood to the organs. (jia1669.com)
  • A chest radiography and blood work (eg, complete blood count, chemistry, liver function test, lipase) may prove useful in ruling out other causes. (medscape.com)
  • He had the onset of chest discomfort at rest and presented by ambulance about 3 hours later with "severe crushing chest pain," with a blood pressure of 200/100 and pulse of 100. (blogspot.com)
  • On the other hand, Erythema multiforme major (also known as Stevens Johnson syndrome ) is a severe allergic reaction resulting in large blood blisters. (targetwoman.com)
  • In myelodysplastic syndrome (MDS), a slowly developing form of cancer that can devolve into acute leukemia, abnormal stem cells reproduce within the bone marrow, where they die prematurely -- decreasing their ability to produce red and white blood cells and platelets. (uexpress.com)
Radiography1
  • Chest radiography may reveal pulmonary edema. (medscape.com)
Kidney injury1
  • Activated CD47 regulates multiple vascular and stress responses: implications for acute kidney injury and its management. (navbo.org)
Hospitalization1
  • Few randomized controlled trials have examined the efficacy time of smoking cessation in hospitalized patients with acute coronary syndrome, either during hospitalization or after discharge. (who.int)
Cardiac arrest4
  • Let's find out the truth about this acute cardiac arrest. (jia1669.com)
  • Heart Association Statistics of the United States Acute cardiac arrest can occur for many reasons. (jia1669.com)
  • For people over 35 years of age, the most common risk factors for acute cardiac arrest include diabetes, hyperlipidemia. (jia1669.com)
  • 3 examined 5,615 athletes and concluded that, despite the use of electrocardiograms, to screen for the risk of birth acute cardiac arrest In those under 35 years of age, it is better than taking a history and physical examination. (jia1669.com)
Asthma1
  • Respiratory causes such as asthma can present with chest pain without any audible wheezing. (aliem.com)
Predictor1
  • Reticulocyte count is the most important predictor of acute cerebral ischemia and high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia. (cdc.gov)