Glucose: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.Blood Glucose: Glucose in blood.Glucose Tolerance Test: A test to determine the ability of an individual to maintain HOMEOSTASIS of BLOOD GLUCOSE. It includes measuring blood glucose levels in a fasting state, and at prescribed intervals before and after oral glucose intake (75 or 100 g) or intravenous infusion (0.5 g/kg).Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.Glucose Oxidase: An enzyme of the oxidoreductase class that catalyzes the conversion of beta-D-glucose and oxygen to D-glucono-1,5-lactone and peroxide. It is a flavoprotein, highly specific for beta-D-glucose. The enzyme is produced by Penicillium notatum and other fungi and has antibacterial activity in the presence of glucose and oxygen. It is used to estimate glucose concentration in blood or urine samples through the formation of colored dyes by the hydrogen peroxide produced in the reaction. (From Enzyme Nomenclature, 1992) EC 1.1.3.4.Glucose Transporter Type 1: A ubiquitously expressed glucose transporter that is important for constitutive, basal GLUCOSE transport. It is predominately expressed in ENDOTHELIAL CELLS and ERYTHROCYTES at the BLOOD-BRAIN BARRIER and is responsible for GLUCOSE entry into the BRAIN.Glucose Transporter Type 4: A glucose transport protein found in mature MUSCLE CELLS and ADIPOCYTES. It promotes transport of glucose from the BLOOD into target TISSUES. The inactive form of the protein is localized in CYTOPLASMIC VESICLES. In response to INSULIN, it is translocated to the PLASMA MEMBRANE where it facilitates glucose uptake.Monosaccharide Transport Proteins: A large group of membrane transport proteins that shuttle MONOSACCHARIDES across CELL MEMBRANES.Blood Glucose Self-Monitoring: Self evaluation of whole blood glucose levels outside the clinical laboratory. A digital or battery-operated reflectance meter may be used. It has wide application in controlling unstable insulin-dependent diabetes.Glucose 1-Dehydrogenase: A glucose dehydrogenase that catalyzes the oxidation of beta-D-glucose to form D-glucono-1,5-lactone, using NAD as well as NADP as a coenzyme.Deoxyglucose: 2-Deoxy-D-arabino-hexose. An antimetabolite of glucose with antiviral activity.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Glucose Transporter Type 2: A glucose transport facilitator that is expressed primarily in PANCREATIC BETA CELLS; LIVER; and KIDNEYS. It may function as a GLUCOSE sensor to regulate INSULIN release and glucose HOMEOSTASIS.Glucose Transporter Type 3: A major glucose transporter found in NEURONS.Fasting: Abstaining from all food.GlycogenDiabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.Glucagon: A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)Hypoglycemic Agents: Substances which lower blood glucose levels.Glucose Dehydrogenases: D-Glucose:1-oxidoreductases. Catalyzes the oxidation of D-glucose to D-glucono-gamma-lactone and reduced acceptor. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.47; EC 1.1.1.118; EC 1.1.1.119 and EC 1.1.99.10.Glycolysis: A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.Gluconeogenesis: Biosynthesis of GLUCOSE from nonhexose or non-carbohydrate precursors, such as LACTATE; PYRUVATE; ALANINE; and GLYCEROL.Islets of Langerhans: Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.Lactates: Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)Hexokinase: An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-Glucose, D-mannose, D-fructose, sorbitol, and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase. (From Enzyme Nomenclature, 1992) EC 2.7.1.1.Glucose-6-Phosphate: An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)Glucokinase: A group of enzymes that catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate. They are found in invertebrates and microorganisms, and are highly specific for glucose. (Enzyme Nomenclature, 1992) EC 2.7.1.2.Fructose: A monosaccharide in sweet fruits and honey that is soluble in water, alcohol, or ether. It is used as a preservative and an intravenous infusion in parenteral feeding.Biological Transport: The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.GlucosephosphatesGlucose Metabolism Disorders: Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology of these disorders varies. Plasma glucose concentration is critical to survival for it is the predominant fuel for the CENTRAL NERVOUS SYSTEM.3-O-Methylglucose: A non-metabolizable glucose analogue that is not phosphorylated by hexokinase. 3-O-Methylglucose is used as a marker to assess glucose transport by evaluating its uptake within various cells and organ systems. (J Neurochem 1993;60(4):1498-504)Fatty Acids, Nonesterified: FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.MethylglucosidesPhlorhizinKinetics: The rate dynamics in chemical or physical systems.Sodium-Glucose Transporter 1: The founding member of the sodium glucose transport proteins. It is predominately expressed in the INTESTINAL MUCOSA of the SMALL INTESTINE.Diabetes Mellitus, Experimental: Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Homeostasis: The processes whereby the internal environment of an organism tends to remain balanced and stable.Energy Metabolism: The chemical reactions involved in the production and utilization of various forms of energy in cells.Glycerol: A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.C-Peptide: The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.Postprandial Period: The time frame after a meal or FOOD INTAKE.Insulin-Secreting Cells: A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.Adipose Tissue: Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.Carbohydrate Metabolism: Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES.Dietary Carbohydrates: Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)Glucose Solution, Hypertonic: Solution that is usually 10 percent glucose but may be higher. An isotonic solution of glucose is 5 percent.Hemoglobin A, Glycosylated: Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.Glycosuria: The appearance of an abnormally large amount of GLUCOSE in the urine, such as more than 500 mg/day in adults. It can be due to HYPERGLYCEMIA or genetic defects in renal reabsorption (RENAL GLYCOSURIA).Obesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).Glucose-6-Phosphatase: An enzyme that catalyzes the conversion of D-glucose 6-phosphate and water to D-glucose and orthophosphate. EC 3.1.3.9.Carbon Isotopes: Stable carbon atoms that have the same atomic number as the element carbon, but differ in atomic weight. C-13 is a stable carbon isotope.Liver Glycogen: Glycogen stored in the liver. (Dorland, 28th ed)Uridine Diphosphate Glucose: A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.Glucagon-Like Peptide 1: A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
Active Ingredient: Menthol 7 mg. Inactive Ingredients: Eucalyptus Oil, FD&C Blue 2, FD&C Red 40, Flavors, Glucose Syrup, Soy ... Active Ingredient: Menthol 3.1 mg. Inactive Ingredients: FD&C red no. 40, Flavorings, Glucose Syrup, Sucrose, Water. *Wild ... Active Ingredients: Menthol 19.7 mg, Eucalyptus oil 9.8mg. Inactive Ingredients: Citric acid, FD&C Blue No.1, flavors, glucose ... Inactive Ingredients: Flavorings, Glucose Syrup, Red 40, Sucrose. *Sunshine Citrus. Active Ingredient: Menthol 2.5 mg. Inactive ...
Rather than oxidizing glucose for ATP production, glucose in cancer cells tends to be used for anabolic processes, such as ... They are also found to interact with arginine residues required for isocitrate binding in the active site of the proteins of ... p53 activates hexokinase 2 (HK2) that converts glucose to glucose-6-phosphate (G6P) which enters glycolysis to produce ATP, or ... Uridine diphosphate glucose-glucose synthesis, glycerol synthesis and Pentose phosphate pathway or PPP. It helps in generating ...
The body uses glucose for energy. Without insulin, glucose is unable to enter the cells where it will be used for this and ... Insulin is also an active preventor of the breakdown or catabolism of glycogen and fat. The absence of sufficient insulin ... Since the glucose that normally enters the cells is unable to do so without insulin, it begins to build up in the blood where ... Urine glucose testing strips have a negative result until the renal threshold of 10 mmol/L or 180 mg/dL is reached or exceeded ...
It can uptake both glucose and xylose simultaneously. When grown in old oil with high levels of polymerized triglyceride, the ... 2010) Molecular evidence that phylogenetically diverged ciliates are active in microbial mats of deep-sea cold-seep sediment. ...
If glucose is given, such as in hypoglycaemic alcoholics, thiamine must be given concurrently. If this is not done, the glucose ... Thiamine is first metabolised to its more active form, thiamine diphosphate (TDP), before it is used. The body only has 2-3 ... Thiamine, also called B1, helps to break down glucose. Specifically, it acts as an essential coenzyme to the TCA cycle and the ... requirement for IV glucose, signs of malnutrition, poor diet, recent diarrhea or vomiting, peripheral neuropathy, intercurrent ...
Products of the reaction are the constituent monosaccharides glucose and fructose. This glucose is added to a growing glucan ... Both sucrose breakdown and glucan synthesis occur in the same active site. The first step is carried out through a ... This occurred because the active sites of the two enzymes are nearly the same. Glucansucrase likely maintained a highly- ... Additional investigations pointed to a non-reducing mechanism with a single active site. Glucansucrase proteins likely evolved ...
The body's primary source of energy is glucose; however, when all the glucose in the body has been expended, a normal body ... Most individuals with a fatty-acid metabolism disorder are able to live a normal active life with simple adjustments to diet ... When in need of glucose the body of a person with a fatty-acid metabolism disorder will still send fats to the liver. The fats ... It is essential that the blood-glucose levels remain at adequate levels to prevent the body from moving fat to the liver for ...
Phosphorylase a serves as a glucose sensor in liver cells. When glucose levels are low, phosphorylase a in its active R state ... Therefore, there phosphorylase a will accelerate glycogen breakdown until adequate levels of glucose are achieved. When glucose ... PP1 plays a crucial role in the regulation of blood-glucose levels in the liver and glycogen metabolism. PP1 is important to ... When the muscles of the body signal for the need for glycogen degradation and increased glucose concentration, PP1 will be ...
... is active when blood glucose is high. The basic functions of insulin and glucagon are to maintain glucose ... The most active of these is monacolin K, or lovastatin (previously sold under the trade name Mevacor, and now available as ... Lin YL, Wang TH, Lee MH, Su NW (Jan 2008). "Biologically active components and nutraceuticals in the Monascus-fermented rice: a ... with the active site located in a long carboxyl terminal domain in the cytosol. More recent evidence shows it to contain eight ...
The Leloir pathway catalyzes the conversion of galactose to glucose. Galactose is found in dairy products, as well as in fruits ... Recently, the roles of active site residues in human galactokinase have become understood. Asp-186 abstracts a proton from C1- ... Galactokinase from S. cerevisiae, on the other hand, is highly specific for D-galactose and cannot phosphorylate glucose, ... As galactose is not being catabolized to glucose due to a galactokinase mutation, galactitol accumulates. This galactitol ...
Nerve cells require oxygen and glucose for energy. 2-deoxyglucose (2DG) is a radioactive glucose isotope that can be tracked in ... Today, one of the most active food psychologists, Paul Rozin has been the first to successfully map the role of retronasal ... After stimulation of a certain region of cells, X-ray photographs can be sliced to reveal which cells were active, particularly ... During quiet breathing, this cartridge directs the stream of air normally, but during active smelling, the rate of direction of ...
... glucose trimming is responsible for the conformational change needed for LPL to form homodimers and become catalytically active ... The active site of LPL is composed of the conserved Ser-132, Asp-156, and His-241 triad. Other important regions of the N- ... The glycerol backbone of the lipid is then able to enter the active site and is hydrolyzed. Two molecules of ApoC-II can attach ... The lipid interacts with both the lid region and the hydrophobic groove at the active site; this causes the lid to move, ...
... upregulates the GLUT1 glucose transporter, thereby contributing to the Warburg effect in cancer cells.[9] KRAS binds to ... 1lfd: CRYSTAL STRUCTURE OF THE ACTIVE RAS PROTEIN COMPLEXED WITH THE RAS-INTERACTING DOMAIN OF RALGDS ... 6q21: MOLECULAR SWITCH FOR SIGNAL TRANSDUCTION: STRUCTURAL DIFFERENCES BETWEEN ACTIVE AND INACTIVE FORMS OF PROTOONCOGENIC RAS ... "results indicate that oncrasin-1 or its active analogues could be a novel class of anticancer agents which effectively kill K- ...
One active compound is daphnin, a glycoside, combining glucose with daphnetin. Some species have been shown to contain a ...
It is a highly active carbonic anhydrase inhibitor. The molecule contains a gallagic acid component linked to a glucose. Zhang ...
The brain does not store glucose, its primary source of energy. When neurons become active, getting them back to their original ... Usually the brought-in oxygen is more than the oxygen consumed in burning glucose (it is not yet settled whether most glucose ... The energy for those ion pumps is mainly produced from glucose. More blood flows in to transport more glucose, also bringing in ... is active at that time point. One then assumes a specific shape for the HDR, leaving only its amplitude changeable in active ...
... is a carbohydrate-hydrolase that releases alpha-glucose as opposed to beta-glucose. Beta-glucose residues can ... It was shown that 1-deoxynojirimycin (DNJ) would bind the strongest of the sugars tested and blocked the active site of the ... linked alpha-glucose residues to release a single alpha-glucose molecule. ... This leads to a conclusion that the enzyme's active site conformation is less stable than the whole enzyme conformation in ...
A feature of many ß-glucosidases are catalytic glutamate residues at their active sites, but two of these have been replaced by ... However, myrosinase is the only known enzyme found in nature that can cleave a thio-linked glucose. Its known biological ... In the presence of water, myrosinase cleaves off the glucose group from a glucosinolate. The remaining molecule then quickly ... See Figure 2.) First, the β-thioglucoside linkage is cleaved by myrosinase, releasing D-glucose. The resulting aglycone ...
... of the glucose reabsorption in the kidney. Blocking this transporter causes blood glucose to be eliminated through the urine. ... The remaining structure, which is the active substance, is called sergliflozin. World Health Organization (2008). " ... validates the critical role of SGLT2 in renal glucose reabsorption and modulates plasma glucose level". J Pharmacol Exp Ther. ... It did not undergo further development after phase II.[citation needed] Sergliflozin inhibits subtype 2 of the sodium-glucose ...
The isotope is chemically incorporated into a biologically active molecule, such as glucose, which powers metabolic activity. ... For example, when a patient is asked to tap out a beat or try to reproduce a tone, this region is very active on fMRI and PET ... When neurons become active blood flow to those regions increases. This oxygen-rich blood displaces oxygen depleted blood in ... Some of the above-mentioned areas have been shown to be active in both music and language processing through PET and fMRI ...
Amylose is a linear polymer of glucose mainly linked with α(1→4) bonds. It can be made of several thousands of glucose units. ... which suits the active lives of moving animals. ... Starch is a glucose polymer in which glucopyranose units are ... The formations of starches are the ways that plants store glucose.. Glycogen[edit]. Glycogen serves as the secondary long-term ... Glycogen is analogous to starch, a glucose polymer in plants, and is sometimes referred to as animal starch,[13] having a ...
Hypoglycosylated IGFBP-3 may be seen after extended glucose starvation. Many proteases are known to cleave IGFBP-3 at single ... that together maintain an active IGF-binding site. IGFBP-3 mRNA is expressed in all tissue examined, with kidney, stomach, ...
Glucose crosses the apical membrane of the enterocyte using the sodium-glucose cotransporter. It moves through the cytosol ( ... This typically occurs through active transport. Water uptake. This follows the osmotic gradient established by Na+/K+ ATPase on ...
... has one primary advantage over regular insulin for postprandial glucose control. It has a shortened delay of ... This allows larger amounts of active monomeric insulin to be immediately available for postprandial injections. ...
When glucose levels are high, insulin and therefore IGF is produced. This signaling activates the PI3K/AKT pathway which works ... When there are low amounts of available energy, the PI3K/AKT pathway is less active and cells adopt a quiescent state. This ... In this way, when there is high glucose and abundant energy in the organism, the PI3K/AKT pathway is activated and NSCs tend to ...
Corn starch-filled, glucose-sweetened pie with made with sub-standard canned pineapple, artificial (citric acid) lemon flavor ... In the final analysis, the authors encourage consumers to be more active and questioning in their purchasing habits. Consumers ...
Transfection of primary human myotubes with a constitutively active AMPK adenovirus also stimulated GLUT4 mRNA, providing ... Glycogen availability can influence glucose transporter 4 (GLUT4) expression in skeletal muscle through unknown mechanisms. The ...
The liver can store glucose and can produce new glucose from various metabolic precursors. In response to the hormone glucagon ... The liver is the most metabolically active tissue in the human body accounting for 27% of basal metabolic rate (BMR).[7] The ... which signals low blood glucose concentrations, the liver can secrete glucose into the blood to reestablish normal values. ... The liver tops the heart (≈ 60 beats/min), the lungs, and brain, all of which are highly active body tissue. ...
Effects of several inhibitors on the glucose dehydrogenase (EC 1. 1.99.17) from Pseudomonas fluorescenswere studied. 2,3- ... An active site model and a possible reaction mechanism are proposed.. Keywords. Pseudomonas Fluorescens Glucose Dehydrogenase ... Imanaga Y., Suzuki S., Yoshitomi J., Murase H. and Minami Y.(1985) On the active site of membrane-bound glucose dehydrogenase ... Tsutsumi R., Ikawa K. and Imanaga Y.(1987) On the active site of membrane-bound glucose dehydrogenase from Pseudomonas ...
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An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate ... ACTIVE SITE MUTANT (D177->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES. ... Glucose 6-phosphate dehydrogenase-like Glucose 6-phosphate dehydrogenase Leuconostoc mesenteroides [TaxId: 1245] ... GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE (1E7M:A) * Glucose 6 Phosphate Dehydrogenase Activity ...
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as Particularly Active Glucose Assimilators in a Complex Murine Microbiota Cultured In Vitro. Elena Herrmann,1 Wayne Young,2 ... M. Egert, A. A. De Graaf, A. Maathuis et al., "Identification of glucose-fermenting bacteria present in an in vitro model of ... R. P. Ferraris, S. Yasharpour, K. C. K. Lloyd, R. Mirzayan, and J. M. Diamond, "Luminal glucose concentrations in the gut under ...
A Single Dose of Beetroot Gel Rich in Nitrate Does Not Improve Performance but Lowers Blood Glucose in Physically Active ... "A Single Dose of Beetroot Gel Rich in Nitrate Does Not Improve Performance but Lowers Blood Glucose in Physically Active ...
Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma Active Not Recruiting Phase 1 / 2 Trials for Beta-D-Glucose (DB02379) ...
Subjects were randomized to two groups: one group used a blood glucose-monitoring device, kept a blood glucose/eating diary, ... Active Low-Carber Forums , Main Low-Carb Diets Forums & Support , Low Carb Health & Technical Forums , Dr.Bernstein & Diabetes ... Welcome to the Active Low-Carber Forums. Support for Atkins diet, Protein Power, Neanderthin (Paleo Diet), CAD/CALP, Dr. ... Those in the intervention group used a blood glucose monitoring device before and after 3 main meals on 2 days a week, and kept ...
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The movement of glucose from the intestinal lumen into the blood stream requires secondary active transport. Which type of work ... The movement of glucose from the intestinal lumen into the blood stream requires secondary active transport. Which type of work ... The movement of glucose from the intestinal lumen into the blood stream requires secondary active transport. Which type of work ...
Aerobic glucose metabolism is normally indispensable for metabolically active cells; nevertheless,. February 13, 2018 4:41 am. ... Aerobic glucose metabolism is normally indispensable for metabolically active cells; nevertheless, the regulatory mechanism of ... Down-regulated PDH activity credited to knockdown inhibited glucose-stimulated oxidative tension in RPE cells. Our present data ...
Apple has reportedly hired a team of biomedical engineers to develop noninvasive glucose sensors for integration in Apple Watch ... Active Forum Topics. * 166. iPhone replacement cycles slowing down to four years, pose threat to services, analyst say... ... Apple working on breakthrough glucose sensors for Apple Watch, report says. By Mikey Campbell Wednesday, April 12, 2017, 06:30 ... Though his previous work focused on diabetes, it is unclear if Kumar is part of Apples glucose monitoring technology team. ...
Find out about prediabetes tests, such as the A1C test and the oral glucose tolerance test. Also learn how to manage ... Get active. Exercise is also important for managing your blood glucose. Aim for 30 minutes of exercise five days a week. ... Oral glucose tolerance test (OGTT). The oral glucose tolerance test (OGTT) takes a little more time than the other two glucose ... Random plasma glucose (RPG) test. A random blood glucose (RPG) test is a blood test thats performed any time of day that you ...
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  • Half a century later this idea has turned into one of the most studied of all transporter proteins (SGLT1), the sodium-glucose cotransporter. (wikipedia.org)
  • The SLC5A1 gene provides instructions for producing a protein called sodium/glucose cotransporter protein 1 (SGLT1). (medlineplus.gov)
  • Examples of facilitated diffusion are the passing of K+ ions through a membrane with an aid of a potassium transport protein and the passing of glucose and amino acids with the aid of proteins called permeases. (reference.com)
  • however, other proteins in the kidneys are able to absorb enough glucose into the bloodstream, so that glucosuria is mild, if present at all, in people with glucose-galactose malabsorption. (medlineplus.gov)
  • View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage) , the pathway pentose phosphate pathway and in Carbohydrate degradation . (uniprot.org)
  • Glucose is then exported from the cell via glucose transporter membrane proteins . (wikipedia.org)
  • Glucose 6-phosphatase is a complex of multiple component proteins, including transporters for G6P, glucose, and phosphate. (wikipedia.org)
  • RESULTS After 12 weeks, dapagliflozin induced moderate glucosuria (52-85 g urinary glucose/day) and demonstrated significant glycemic improvements versus placebo (ΔA1C −0.55 to −0.90% and ΔFPG −16 to −31 mg/dl). (diabetesjournals.org)
  • Falciparum malaria increases glucose production by approximately 25% in adult patients (E Dekker et al. (malariaworld.org)
  • In contrast, the adipocyte-secreted hormone resistin increases glucose production by the liver, probably by inactivating AMPK ( 4 ). (diabetesjournals.org)
  • In this context, CGM refers to the measurement of the level of glucose in the body on a regular (typically 5 minute) basis through a sensor continuously attached to the person. (ieee.org)
  • The Thermus thermophilus xylA gene encoding xylose (glucose) isomerase was cloned and expressed in Saccharomyces cerevisiae under the control of the yeast PGK1 promoter. (lu.se)
  • Mutations in the SLC5A1 gene cause glucose-galactose malabsorption. (medlineplus.gov)
  • We investigated the effect of a short-term overexpression of AMPK specifically in the liver by adenovirus-mediated transfer of a gene encoding a constitutively active form of AMPKα2 (AMPKα2-CA). Hepatic AMPKα2-CA expression significantly decreased blood glucose levels and gluconeogenic gene expression. (diabetesjournals.org)
  • The threshold below which parasite proliferation is impaired falls well in the range of normal blood glucose levels in vivo. (malariaworld.org)
  • A percutaneous device as model to study the in vivo performance of implantable amperometric glucose sensors. (semanticscholar.org)
  • An improved glucose sensor adapted for in vivo implantation includes one or more optical fiber optrodes mounted within a semipermeable probe housing designed for differential diffusion of glucose and oxygen. (google.com.au)
  • They were potent, systemically active NMDA receptor antagonists in vivo against responses of single neurons in the rat spinal cord to microelectrophoretic application of NMDA with ID 50 values in the low milligram per kilogram i.v. range. (aspetjournals.org)
  • Small amounts of the simple sugar glucose in the urine (mild glucosuria) may occur in this disorder. (medlineplus.gov)
  • Epithelial cells lining the gut need to bring glucose made available from digestion into the body and must prevent the reverse flow of glucose from body to gut. (phschool.com)