Activation analysis in which the specimen is bombarded with neutrons. Identification is made by measuring the resulting radioisotopes. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A method of chemical analysis based on the detection of characteristic radionuclides following a nuclear bombardment. It is also known as radioactivity analysis. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Determination of the energy distribution of gamma rays emitted by nuclei. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.
A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Stable zinc atoms that have the same atomic number as the element zinc, but differ in atomic weight. Zn-66-68, and 70 are stable zinc isotopes.
A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002,1985), chromium and some of its compounds have been listed as known carcinogens.
An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.
A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.
The relative amounts of various components in the body, such as percentage of body fat.
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules.
The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.
The systematic study of the complete complement of proteins (PROTEOME) of organisms.
Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions.
Substances that are toxic to the intestinal tract causing vomiting, diarrhea, etc.; most common enterotoxins are produced by bacteria.
Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.
Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include, but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
Plugs or cylinders made of cotton, sponge, or other absorbent material. They are used in surgery to absorb fluids such as blood or drainage.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.
A highly toxic gas that has been used as a chemical warfare agent. It is an insidious poison as it is not irritating immediately, even when fatal concentrations are inhaled. (From The Merck Index, 11th ed, p7304)
The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. Glycosyl transferases are used in this biochemical reaction.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.

A bone calcium index based on partial-body calcium measurements by in vivo activation analysis. (1/35)

Measurements of partial-body calcium by in vivo neutron activation analysis have been carried out on normal and osteoporotic subjects. Based on measurements on 16 normal subjects (volunteers less than 55 years of age), a calcium index has been established that takes into account variation in skeletal frame size. On the basis of this index, all osteoporotic patients have bone mineral content less than any of the normal subjects. The normal calcium indices range from 0.9 to 1.2, and the osteoporotic indices ranged from 0.41 to 0.83. Thirteen of 22 volunteers over 55 years of age had calcium indices less than 0.9 in agreement with the expected loss of calcium with age. Measurements of total-body potassium were also made on these same subjects and the calcium/potassium ratios calculated. Although as groups the older volunteers and older osteoporotic subjects had mean calcium/potassium ratios similar to the mean for the normal subjects, the osteoporotic subjects under 55 years of age had a mean calcium/potassium ratio significantly lower, indicationg that for this latter group the loss in bone mineral was not associated with a corresponding loss in muscle mass.  (+info)

Phonton absorptiometry and skeletal mass in the treatment of osteoporosis. (2/35)

Thirty-six osteoporotic patients who underwent several therapeutic regimes were studied on two occasions by photon absorptiometry and total-body neutron activation analysis (TBNAA). These determinations were made at a mean interval of 8.9 plus or minus 0.8 months. The 8-cm radial site was chosen for the photon absorptiometry which was performed with the Norland-Instruments Densitometer. Mean initial bone mineral content (BMC) was 0.724 plus or minus 0.069 gm/cm and mean bone width was 1.235 plus or minus 0.072 cm. The mean percent change in BMC (%deltaBMC) was 1.02 plus or minus 4.2. The initial total-body calcium (TBCa) as determined by TBNAA was reduced when compared with values that would be expected from empirically derived formulas. The mean percent change in TB-Ca (%deltaTB-Ca) was -3.2 plus or minus 4.7. Most patients displayed a change in BMC and TB-Ca that was at least 2 s.d. greater than the precision of the methods used (%deltaTB-Ca greater than 2). No relationship was found between the deltaBMC and the deltaTB-Ca (r = 0.17). These findings suggest that changes in the radical BMC at the 8-cm site cannot be extrapolated to indicate changes in skeletal mass in response to treatment of osteoporosis. Whether photon absorptiometry at other sites or at multiple sites provides a closer relationship to changes in skeletal mass (TB-Ba) remains to be determined.  (+info)

Preliminary observations on excretion of 37Ar from man following whole-body neutron activation--an indicator of total-body calcium. (3/35)

Measurements of exhaled 37-Ar produced by total-body neutron irradiation of 40-Ca were used to determine total-body calcium in 16 human subjects. There was a good correlation between body calcium using the 30-min postirradiation breath sample of 37-Ar and body calcium determined by measurement of 49-Ca.  (+info)

Effects of activation sequence on the local recovery of ventricular excitability in the dog. (4/35)

We measured refractory periods at ventricular sites in the dog heart during drive from ventricular test sites and during combined drive from the test sites and other ventricular sites or the atrium. We found that ventricular activation sequence caused significant alterations on refractory period. Combined drive from two sites which resulted in fusion complexes was associated with shorter refractory periods at the test sites than those observed during drive at the test sites only. Our findings are explicable because earlier excitation and consequent earlier recovery of surrounding areas during fusion beats exerts an electrotonic influence on test sites.  (+info)

Length-induced changes in activation during contraction. A study of mechanical oscillations in strontium-mediated contractions of cat and frog heart muscle. (5/35)

The plateau phase of prolonged Sr-mediated contractions of preparations of cat and frog heart muscle was used to study the transient response to abrupt changes in load or length. An oscillatory response (total amplitude equal to or less than 5% Lmax) was obtained. Isotonic oscillations were less damped than their isometric counterparts, implying positive feedback and thus a causal role of the perturbation in length. Oscillation frequency was 2-3 HZ at 29 degrees C (Q 10, 2-3); it could be increased by epinephrine or caffeine, independently of their effects on extent of shortening; it otherwise changed as a generally constant function of the length at which the oscillation occurred, whether this was altered by changes in extracellular [Sr], frequency of contraction, or load (independent of the direction and magnitude of the preceding load step). Similar oscillatory responses were induced during Sr- or Ca-mediated contractures. Cat muscles showed an additional slower component to the oscillatory response. Transient augmentation of the velocity-length relationship after abrupt reduction in load, previously described for twitch contractions under certain conditions, appears to be analogous to the first phase of the oscillatory response studied here. Our findings indicate that the oscillation is not attributable to any mechanism intrinsic to myofilament interaction, but rather that it involves length-induced changes in the level of activation, probably mediated by Ca2+ or Sr2+. We conclude that length influences the level of activation during contraction of heart muscle.  (+info)

MICROSCOPIC DETERMINATION OF BONE PHOSPHORUS BY QUANTITATIVE AUTORADIOGRAPHY OF NEUTRON-ACTIVATED SECTIONS. (6/35)

Longitudinal sections of human cortical bone were submitted to thermal neutrons. gamma-ray spectra were recorded repeatedly during 15 days following irradiation. They showed that Na(24) is predominant as early as 3 hours after activation and that all the gamma-emitters have decayed on the 15th day. When the gamma-rays have disappeared, beta-rays are still produced by the sections. It was proved by the absorption curve in aluminium that all these beta-rays are issued from the P(32) induced in the sections by activation of P(31). Therefore autoradiograms registered 15 days after activation reveal the distribution of P(32) in the sections. gamma-ray spectra and beta-ray absorption curves of neutron activated sections of ivory demonstrated a mineral composition similar to that of bone. Autoradiograms of ivory sections activated for various times were used to establish the relation between the optical density of the autoradiograms and the radioactivity in P(32). When the bone autoradiograms are compared with the ivory standards of known radioactivity, the optical densities of single osteons (Haversian systems), can be related to their phosphorus contents. Autoradiograms and microradiograms of the same sections were examined side by side. The least calcified osteons, that contain 80 per cent of the calcium of the fully calcified osteons, also contain about 80 per cent of the phosphorus of the fully mineralized osteons. It is concluded that the Ca:P ratio remains constant while mineralization of bone tissue is being completed.  (+info)

Heparin-stimulated inhibition of factor IXa generation and factor IXa neutralization in plasma. (7/35)

Generation and inhibition of activated factor IXa was studied in factor XIa-activated plasma containing 4 mmol/L free calcium ions and 20 mumol/L phospholipid (25 mol% phosphatidylserine/75 mol% phosphatidylcholine). Interference of other (activated) clotting factors with the factor IXa activity measurements could be avoided by using a highly specific and sensitive bioassay. Factor IXa generation curves were analyzed according to a model that assumed Michaelis-Menten kinetics of factor XIa-catalyzed factor IXa formation and pseudo first order kinetics of inhibition of factor XIa and factor IXa. In the absence of heparin, factor IXa activity in plasma reached final levels that were found to increase with increasing amounts of factor XIa used to activate the plasma. When the model was fitted to this set of factor IXa generation curves, the analysis yielded a rate constant of inhibition of factor XIa of 0.7 +/- 0.1 min-1 and a kcat/Km ratio of 0.29 +/- 0.01 (nmol/L)-1 min-1. No neutralization of factor IXa activity was observed (the estimated rate constant of inhibition of factor IXa was 0). Thus, in the absence of heparin, the final level of factor IXa in plasma is only dependent on the initial factor XIa concentration. While neutralization of in situ generated factor IXa in normal plasma was negligible, unfractionated heparin dramatically enhanced the rate of inactivation of factor IXa (apparent second order rate constant of inhibition of 5.2 min-1/per microgram heparin/mL). The synthetic pentasaccharide heparin, the smallest heparin chain capable of binding antithrombin III, stimulated the inhibition of in situ generated factor IXa, but sevenfold less than unfractionated heparin (k = 0.76 min-1 per microgram pentasaccharide/mL). We found that free calcium ions were absolutely required to observe an unfractionated heparin and pentasaccharide-stimulated neutralization of factor IXa activity. Factor XIa inhibition (psuedo first order rate constant of 0.7 min-1) was not affected by unfractionated heparin or pentasaccharide in the range of heparin concentrations studied.  (+info)

Post-separation detection of nucleic acids and proteins by neutron activation. (8/35)

We describe approaches to neutron activation analysis and their application to post-separation autoradiographic detection of biological compounds. Specifically, we have extended the use of a "direct-labeling" method to the post-separation detection of DNA after gel electrophoresis and to the detection of nucleotides separated by TLC. In addition, we describe a more generally applicable "indirect-labeling" method in which separated compounds of interest are selectively bound to ligands containing highly neutron-activatable elements, such as manganese (55Mn), europium (151Eu), or dysprosium (164Dy), and then irradiated with thermal neutrons. This method is illustrated with nucleotides separated by TLC and with proteins separated by polyacrylamide gel electrophoresis. In contrast to the direct-labeling approach, the indirect-labeling method can be adapted to detect any class of substances for which a highly neutron-activatable, selectively binding ligand is available. The theoretically achievable sensitivity of the indirect-labeling method is in the attomole (10(-18) mol) range.  (+info)

Calcium is an essential daily nutrient. Critical functions of life are dependent on narrow concentration limits for plasma calcium, which is subject to obligatory losses from the body requiring a complex homeostatic mechanism and a daily nutrient intake. Stringent regulation of plasma calcium homeostasis is maintained by an intricate pathway of agents for which the biologically active metabolite of vitamin D, 1,25-diydroxyvitamin D, is one component. Ninety nine per cent of total body calcium is present in the skeleton. One of its functions is as a store of body calcium. Vitamin D exerts activities as an endocrine agent at the intestine, kidney and bone tissues and as an autocrine/paracrine agent within bone tissue to both stimulate bone mineral resorption and inhibit bone formation or to inhibit bone resorption and stimulate bone formation. These activities are coordinated by a range of regulatory factors to maintain plasma calcium homeostasis with secondary effects on bone-mineral ...
Calcium is the most abundant mineral in the human body and has several important functions. More than 99% of total body calcium is stored in the bones and teeth where it supports the structure. The remaining 1% is found throughout the body in blood,
This blood test checks to see if your are deficient in any of the most common minerals in the body - calcium, iron, chromium, copper, magnesium, manganese and zinc. Order securely online today,
Neutron activation analysis (NAA) is a precise analytical method, which serves to establish the elemental composition of investigated samples, both quantitative and qualitative. The method is based on the transformation of originally stable atoms in the analysed substance into unstable isotopes, after interaction with neutrons produced in the reactor. The break-up of these unstable nuclides is usually accompanied by characteristic gamma radiation, which is possible to measure, and from its amount subsequently to ascertain a representation of the original mother element. The sensitivity of the method is different for different elements, depending on their atomic characteristics and neutron field parameters, in which the irradiation took place. To examine changes in the neutron field it is possible using NAA methods to use one of three types of standardisation: absolute, relative or comparative.. The LVR-15 reactor is equipped with one channel with pneumatic equipment which allows rapid transport ...
Research on the application of soluble, metal chelates for water tracing using thermal neutron activation analysis for tracer determination has led to the development of several tracers with promising solution stabilities (conservative behavior) and determination sensitivities. The solution stabilities of the ethylenediamine tetraacetic acid (EDTA) and the diethylenetriamine pentaacetic acid (DTPA) chelates of the activable elements Cr, Co, Eu, In, Sb, Sc and Tb were evaluated in a series of laboratory, radiotracer experiments conducted under simulated field conditions. They showed that 1) chelation of metals produces highly conservative solution behavior, 2) DTPA is generally better than EDTA for improving tracer behavior, 3) non-chelated metals are rapidly sorbed onto sediments and 4) chelation reduces sorption of metals onto sediments. Field tests of EuDTPA, TbDTPA, InDTPA and Rhodamine B fluorescent dye in a small eastern Washington stream demonstrated that the metal chelates have ...
Instrumental neutron activation analysis was used to assess the concentration of the inorganic trace elements in Korean womens blood serums. It was found that a high concentration of Na and Cl incurs an analytical interference, but the 12 elements such as Br, Ca, Cl, Co, Cr, Cs, Fe, K, Na, Rb, Se and Zn could be determined under the condition of an interference minimization. Serum samples collected from 63 women were analyzed and the concentration level and range of the elements were evaluated. NIST SRMs were analyzed simultaneously for quality control. The average values of the Na and Cl determined in the serum samples were 3,365 and 3,533 mg/l, Ca was 96.4 mg/l and K was 191 mg/l. Besides, Br, Se and Zn have a concentration level of 6.46, 0.13 and 0.98 mg/l, respectively. It was found that there is no significant difference between the present values and the reported values. ...
Accurate estimates for the molecular transport coefficients are critical to predicting the movement of gases in geological media. Here I present a novel methodology for using prompt gamma activation analysis to measure the effective diffusivity of noble gases in a porous medium. I also present a model to estimate the connectivity parameter of a soil from measurements of its saturated conductivity, macro porosity, and pore volume and pore surface fractal dimensions. Experiments with argon or xenon diffusing through a nitrogen saturated geological media were conducted. The noble gas concentration variations at its source were measured using prompt gamma activation analysis and later compared to a numerical diffusion model to estimate the effective diffusion coefficient. Numerical simulations using the estimated diffusivity and the experimental argon data produced results with a correlation parameter R² = 0.98. However, neglecting transport mechanisms other than diffusion largely under-predicted ...
An instrumental neutron activation method for V, Mn and W in alloy steels with a 241 Am/Be isotopic neutron source is described. The samples were irradiated to induce the nuclear reactions 51V(n, γ) 52V, 55Mn(n, γ)56Mn, and 186W(n, γ)187W. The activities were measured with a NaI(TI) detector. Interferences on the measured photopeaks were shown to be negligible by measuring the half-lives of 62V, 56Mn and 187W.These thre elementes were determined in the range 1.512.9% in special steels; manganese in the range 0.51.6% was measured in cast irons. Calibration was done by comparison with results from wet chemistry and x-ray fluorescence spectrometry. The processing times for the vanadium, manganese and tungsten determinations were 11 min, 3 h and 26.3 h, respectively, but these were reduced greatly by intoruding a scheme wherein six samples were simultaneously irradiated and the 56Mn and 187W nuclides were measured sequentially for a series of 66 samples. The average processing time was reduced to ...
Twenty-three (23) industrial, commercial and government laboratories participated in an interlaboratory measurement program using methods of their own choosing. The methods for zinc involved multi-acid digestions followed by iron separation, use of complexing agents and analysis of the filtrate by atomic absorption spectroscopy and fusion of the insoluble, ion exchange and solvent extraction. The determinations involved titrations with ethylenediaminetetraacetate and ferrocyanide, atomic absorption, and instrumental neutron activation analysis. Both fused pellet or fusion followed by X-ray fluorescence, as well as ISO 12739:2006 and ISO/TC 183 N 360 were used by some laboratories.. Other elements were determined by multi acid digestions, microwave digestion, fusion, fire assay (for gold and silver), flame atomic absorption spectroscopy, gravimetric analysis, inductively coupled plasma - optical emission spectroscopy, and instrumental neutron activation analysis. Some laboratories added bromine ...
TY - JOUR. T1 - Comparative PGAA and NAA results of geological samples and standards. AU - Gméling, K.. AU - Simonits, A.. AU - Sziklai László, I.. AU - Párkányi, D.. PY - 2014. Y1 - 2014. N2 - Concentrations of major and trace elements in volcanic rock and soil samples, including geological standard reference materials, were determined by neutron activation analysis (NAA) and prompt gamma activation analysis (PGAA), both using the k0-standardization method. The paper highlights the different experimental procedures, such as sample preparation, data collection and spectrum evaluation. In geological samples, PGAA gives precise results for major elements (Si, Ti, Al, Fe, Mn, Mg, Ca, Na, K and-as a unique method-for H), for some of the light trace elements as B and Cl, as well as for Sc, S, Cr, Co, Ni, Cd, Nd, Sm and Gd. NAA is sensitive for the rare earth elements, and for many major (Ti, Al, Fe, Mn, Mg, Ca, Na, K) and trace elements (e.g.: Sc, V, Cr, Co, Ni, Cu, Zn, As, Se, Rb, Sr, Zr, As, ...
This study compiles and evaluates data from many sources to expand a base of data from which to estimate the activity concentrations and volumes of greater-than-Class C low-level waste that the Department of Energy will receive from the commercial power industry. Sources of these data include measurements of irradiated hardware made by or for the utilities that was classified for disposal in commercial burial sites, measurements of neutron flux in the appropriate regions of the reactor pressure vessel, analyses of elemental constituents of the particular structural material used for the components, and the activation analysis calculations done for hardware. Evaluations include results and assumptions in the activation analyses. Sections of this report and the appendices present interpretation of data and the classification definitions and requirements.
BNA technology is based on a network model to depict functional connectivity. The descriptive network model approach provides insights regarding inter-connectivity of brain networks and can describe the temporal-spatial brain activation patterns applied to various types of data-sets including EEG, MEG and fMRI.. In this study it is proposed that synchronization in brain activity may be disrupted in patients who experience frequent seizures and may correspond to functional impairments (e.g., memory, processing speed). As such, BNA analysis may provide additional data that complement current functional assessments, inform clinical assessment and management of epilepsy, and identify subgroups of patients that might be at risk for poor treatment outcomes. ...
Thermoluminescence and optically stimulated luminescence techniques are used to assess absorbed dose in the components of personal electronics, along with other items such as plastic cards, fabrics, and clothing. There have also been similar efforts for teeth and dental repair ceramics. Since the above-listed techniques cannot distinguish between exposure to internal and external sources, bioassays may be used to assess exposure from internal contamination, including thyroid counting, chest counting, and excretion analysis methods. When a neutron exposure is expected, neutron activation analysis in blood, hair, or other non-biological items is useful. Radiation field mapping can be a useful method for determining locations where doses to individuals may be expected to be high and may complement radiation transport calculations performed for that purpose. Since immediate medical assessment is concerned with tissue reactions (deterministic effects), the quantity of interest for the above dosimetry ...
Coal is difficult to digest but neutron activation analysis (NAA) uses a direct measurement to avoid problems that are common when looking for trace elements in coal.
1. Iron absorption from 10 mg Fe (as ferrous sulphate), labelled with 1.3 mg 58Fe, was measured in fasting, non-anaemic adult subjects by the faecal-balance technique. The measurement was performed twice, each subject being given, in random order, either 50 mg Fe or a placebo 18 h before the 58Fe-labelled FeSO4. 2. The 50 mg Fe load significantly reduced Fe absorption the following day (P less than 0.01), from a mean of 35.4 (SEM 4.6)% to 29.0 (SEM 5.1)%. This points to the importance of strict dietary control during Fe-absorption studies to eliminate bias in results. 3. In a separate study, the feasibility of using 58Fe-enrichment of erythrocytes, measured by neutron activation analysis (NAA), 10 d after a meal labelled with 0.69 mg 58Fe as an index of Fe absorption was examined. The levels of 58Fe in the blood were detectable by NAA. Regression analysis showed a significant relation between 58Fe-enrichment of blood and 58Fe absorption, calculated as the difference between intake and faecal ...
Objectives-To study longitudinal biological monitoring data on urinary and blood cadmium collected in a small cohort of nine workers who had been brazing for several years with solders containing cadmium. Methods-Cadmium was measured by neutron activation analysis in livers and kidneys, and estimates of renal function were carried out in 1983...
Radiation chemistry,br,Topics:,br,- Irradiation methods,br,o Types of irradiation sources and devices,br,o Dosimetrics,br,o Effects of irradiation geometry, thickness of the target etc.,br,o Use of data basis and related computer programmes,br,- Reactions in radiation chemistry in various materials,br,o Basic reactions, formation of intermediates, excited states, ions, electrons and,br,radicals,br,o Reaction of intermediates, formation of stable products,br,o Radiation chemical yields,br,o Kinetics of radiolysis,br,o Reactions in water and water solutions, polymers, metals, nuclear fuel, nutrients,,br,cells etc.,br,- Analytical methods used in radiation chemistry,br,- Application of radiation chemistry,br,o radiation sterilization of medical equipment,br,o radiation sterilization of food stuffs,br,o polymerization and polymer functionalization,br,o etc.,br,12. Nuclear and radioanalytical methods,br,Topics:,br,- Radioimmunoassay (RIA),br,- Neutron activation analysis (NAA) - instrumental and ...
A far cry from the traditional archaeological methods, Dr Popelka-Filcoff, the President-Elect of the International Society for Archaeological Sciences, uses radio-analytical and spectroscopic methods such as neutron activation analysis (NAA) and X-ray fluorescence microscopy (XFM) to unravel the stories of the ochre trade.. Ochre is an iron oxide pigment naturally occurring in a range of red, brown, orange and yellow colours across Australia, and has featured in Aboriginal art for thousands of years.. Dr Popelka-Filcoff is examining the types of ochre used on boomerangs, shields and bark paintings, and matching it to the elemental composition of known ochre sources across the country. By examining the artefacts and researching the chemical and physical characteristics of the pigments, she can piece together key points in the ancient ochre exchange routes.. Ochre is a very culturally important material and because of that, people would travel to various sites to mine the material and would ...
1984) Cystic fibrosis in England and Wales and in Victoria, Australia 1976-1980. Arch. Dis. , 59, 71-83. 85. , Koch C. and H0iby, N. (1996) Improved survival in the Danish Center-treated cystic fibrosis patients: results of aggressive treatment. Pediatr. 273. 99. , Gurkan, M. and Pala, S. (1973) Newborn screening for cystic fibrosis with chloride electrode and neutron activation analysis. Helv. Paediatr. Acta, 28, 165-174. 100. O. ,68,113-119. , 21, 153-158. 86. A. (1998) Inferences for health provision from 101. CDNA copies of these transcripts could then be used as radioactively labeled probes to look for hybridization with DNA fragments from flow-sorted chromosome 7 libraries21. 11, and to look for sequences that were candidates for the CF gene. The task of moving from the genetic map of the region to the precise molecular definition of the disease was a very formidable one because of the physical distance involved. 11 was thought to represent 5000 kb of DNA sequence. A region of this size ...
In 1971 in the southwestern area of the Roman Forum of Corinth a round-bottomed drainage channel was discovered filled with the largest deposit of pottery of the 4th century ever found in the city, some coins, terracotta figurines, and metal and stone objects. This volume publishes the pottery and metal and stone objects, and includes a re-examination of the coins by Orestes Zervos. Some of the cooking ware has been subjected to neutron activation analysis, and a statistical analysis of all recovered pottery has been completed. The contents of Drain 1971-1 are important for the function of the Classical buildings in this part of Corinth, especially Buildings I and II, and for the chronology of the renovation program that included the construction of the South Stoa, which was probably not built before the last decade of the 4th century ...
Quantification of tissue bioaccumulation of titanium dioxide nanoparticles after oral delivery in rats, using a radiotracer approach, neutron activation analysis and mass spectroscopy ...
AA Stands For Alliteration and Assonance, Associate in Arts, Associate of Arts, Acetic Acid, Activation Analysis, Advanced Alloy, Amino Acid, Amino Acrylate, Arachidonic Acid, Ascorbic Acid, Atomic Absorption, Academic Affairs, Advanced Auditing, Alpha Alumni, Alumni Affairs, Ancient Arts, Active Active, Anti Aliasing, Atomic Absorption, Audio Animatronics, Automatic Adjust, Authors Addition, Authors Alteration, Adaptive Algorithm, Almost All, Angle Angle, Argument Analysis, Academic Alliance, Assistant Administrator, Achievement Age. ...
To determine the percent of patients with refractory breast cancer where molecular profiling and RPMA-based protein pathway activation analysis of their tumor, can change the clinical course of their disease (i.e. produce a Growth Modulation Index (GMI) ≥1.3). The GMI is calculated as the ratio of Progression-free survival (PFS) under molecular profiling and RPMA analysis selected treatment to the time to progression (TTP) for the most recent regimen the patient has progressed on ...
Survival analysis 生存分析 ; 生存分析法 ; 存活分析 ; 存活率分析 Job analysis [管理] 工作分析 ; [计] 作业分析 ; 职业分析 ; 职位分析 Factor Analysis [经] 因素分析 ; 因素分析法 ; 因子分析法 ; 因子生态分析 thermal analysis [冶] [分化] 热分析 ; 热分析法 ; 热学分析 ; 热力分析 Static analysis [计] 静态分析 ; 静强度分析 ; 静力学分析 ; 静力计算 modal analysis [力] 模态分析 ; 模式分析 ; 模态 ; 众数分析 activation analysis [分化] 活化分析 ; [核] 激活分析 Fault Analysis [科技] 故障分析 ; 失效分析 ; 事故分析 Reliability Analysis [计] 可靠性分析 ; 信度分析 ; 可靠度分析 ...
Mutations in sorting nexin 10 (Snx10) have recently been found to account for roughly 4% of all human malignant osteopetrosis, some of them fatal. To study the disease pathogenesis, we investigated the expression of Snx10 and created mouse models in which Snx10 was knocked down globally or knocked out in osteoclasts. Endocytosis is severely defective in Snx10-deficient osteoclasts, as is extracellular acidification, ruffled border formation, and bone resorption. We also discovered that Snx10 is highly expressed in stomach epithelium, with mutations leading to high stomach pH and low calcium solubilization. Global Snx10-deficiency in mice results in a combined phenotype: osteopetrosis (due to osteoclast defect) and rickets (due to high stomach pH and low calcium availability, resulting in impaired bone mineralization). Osteopetrorickets, the paradoxical association of insufficient mineralization in the context of a positive total body calcium balance, is thought to occur due to the inability of the
Healthy Care Super Calcium Complex, 400 Chewable TabletsCalcium is the most abundant mineral in the body, and approximately 99% of the bodys calcium exists in the bones. Calcium requirements increase with age, gender, post-menopause, a diet low in calcium, pregnancy and lactation.The major function of calcium is build
Calcium is an essential mineral needed every day for proper health.* 99% of the bodys calcium can be found in the bones and teeth. This mineral pr.... View full details ...
This is THE thread where you can post ANY question about macros like looking for a rogue macro..., what does this macro do..., or a macro that does this..., etc... Be descriptive of what you want. Use QUOTES when you reply to someone!
new op-tions: in-herit height, ver-ba-tim ig-nore per-cent - li-brary skins * new style en-hanced stan-dard jig-saw - li-brary mag-a-zine: * new macro: \if-boxar-rayempty - li-brary break-able: * op-tion break at al-lows neg-a-tive val-ues now. * the al-go-rithm for breaks in-side a mul-ti-col-umn en-vi-ron-ment was im-proved (user code may be af-fected by this change). * new macro: \tcb-break - li-brary minted: * the de-fault set-tings for minted op-tions are sup-ple-mented by break-lines,au-to-gob-ble - new li-brary poster * new macros and en-vi-ron-ments: tcb-poster, \tcb-poster-set, \poster-box, poster-box-env, tcb-poster-width, tcb-poster-height, tcb-poster-colspac-ing, tcb-poster-rows-pac-ing, tcb-poster-columns, tcb-poster-rows, tcb-poster-col-width, tcb-poster-rowheight * new op-tions: poster, columns, rows, colspac-ing, rows-pac-ing, spac-ing, showframe, width, height, pre-fix, cov-er-age, no cov-er-age, boxes, ...
It was found that trace amount of various ions could be effectively adsorbed onto hydrous magnesium oxide from aqueous solution. Attempts were made to investigate the feasibility of using hydrous...
Stability of Macro Creatine Kinases and Creatine Kinase Isoenzymes Compared: Heat Inactivation Test for Determination of Thermostable Creatine ...
Born in Johnsburg, Illinois, in 1925, Roman Schmitt attended the University of Chicago and completed his doctorate in 1953. Schmitt went on to work as an instructor of chemistry at the University of Illinois and pursued post-doc research in physics there. In 1956, Schmitt switched gears and left academia to work as a research staff scientist with General Atomic, a division of the General Dynamic Corporation. At General Atomic, Schmitt specialized in the study of the chemical composition of meteorites for the presence of rare earth elements. This research required the process of nuclear activation analysis, which entails the bombardment of an object with neutrons inside a nuclear reactor and subsequent measurement of the resulting radioactivity. The reactors used in this process had been developed and sold by General Atomic under the name TRIGA (Training, Research, Isotopes, General Atomic).. In 1966, Schmitt came to Oregon State University to develop a nuclear activation analysis laboratory to ...
UCL Discovery is UCLs open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
Continuous M-Reps. In earlier work [4], we developed a deformable modeling framework called the continuous medial representation (cm-rep), which, in simplest terms, is a continuous analog of the m-rep approach by Pizer et al . [3]. Cm-reps are deformable templates that have a special property that the skeleton (medial axis) of the template preserves its branching topology (number and configuration of its branches) during deformation. Furthermore, the skeleton of the deforming template is modeled explicitly as a continuous manifold and the exact geometric relationship between the skeleton and the templates boundary is captured. The skeleton-boundary relationship makes it possible to define a special shape-based coordinate system on the interior of the template. One of the coordinate axes connects points on the skeleton to the corresponding (nearest) points on the boundary, while the other two axes parameterize the skeleton as well as the boundary. As argued in [5], this coordinate system is a natural
The pneumatic fast transfer system position at KAMINI reactor, Indira Gandhi Centre for Atomic Research, India was characterized by determining the epithermal neutron flux shape factor (α) and the sub-cadmium to epithermal neutron flux ratio (f) for k 0-based Neutron Activation Analysis (k 0-NAA). For determination of α value, bare, Cd-ratio and Cd-cover methods were employed using dual and multi monitors namely Au, Zr and Zn. For calculation of f, Au and Zr monitors were used in the case of bare method and Au monitor was used for cadmium ratio and cadmium cover methods. The determined α-value of PFTS indicated a hard epithermal neutron spectrum and the f value indicated about 96 % thermal neutron component. For validation of k 0-NAA method, reference materials namely NIST SRM 1646a (Estuarine Sediment) and BCS Nb-stabilized Stainless Steel (BCS/SS No.261/1) were analyzed. The percentage errors of the determined concentration values of elements were within ±5 % with respect to the certified ...
Hyperkalemia in diabetes is not uncommon, and has been thought to reflect renal retention of potassium. The goal of this study was to test this hypothesis by measuring total body potassium in hyperkalemic diabetic patients and normokalemic diabetic controls. We measured total body potassium (whole body counting of 40K), total body sodium, calcium, and chloride by neutron activation analysis, total body carbon by inelastic neutron scattering, and total body water from the distribution of 3H20.
anganese (Mn) is an essential mineral but is toxic when taken in excess. However, whether its interactions with other minerals in organs and cells are involved in mechanisms underlying Mn toxicity is poorly understood. It was designed a developmental rat model of chronic Mn treatment (Group A: 1 mg MnCl2.4H2) per ml of drinking water; Group B: 10 mg MnCl2.4H2) per ml of drinking water; Group C: 20 mg MnCl2.4H20 per ml of drinking water; Control Group given water without Mn Addition). Employing the model and instrumental neutron activation analysis, two hypotheses were investigated: (i) chronic manganese treatment alters the brain regional distribution of manganese and this altered manganese distribution also leads to region-specific changes of other metals; (ii) chronic manganese treatment induces differential changes in subcellular distributions of metals and electrolytes. In the treated rats, brain Mn level showed dose-related increases, the most pronounced being noted in striatum, ...
Biochemical indicators of renal dysfunction have been compared with liver and kidney cadmium levels measured by neutron activation analysis in a group of 37 cadmium smelters. Higher than normal concentrations of cadmium in the liver reflect past expo
Twenty-one industrial, commercial and government laboratories participated in an interlaboratory measurement program using methods of their own choice.. Methods for the determination of the elements included digestion with various combinations of acids on a hot plate; and various types of fusions followed by the determination using inductively coupled plasma - atomic emission spectroscopy and inductively coupled plasma - mass spectrometry. Instrumental neutron activation analysis and X-ray fluorescence on a pressed powder pellet, fused pellet or after a fusion were used for many elements.. The concentration of carbon was determined using combustion followed by infrared spectrometry.. The concentration of sulphur was determined using combustion followed by infrared spectrometry; acid digestion using four acids or fusions followed by inductively coupled plasma - atomic emission spectroscopy, inductively coupled plasma - mass spectrometry or X-ray fluorescence.. ANOVA was used to calculate the ...
The problem of global contamination from uranium (U) is a difficult task. The present investigation was aimed to study the possibilities of using prostate tissue as a biological material for global environmental monitoring of U. The U content in non-hypertrophic prostate of apparently healthy 64 residents of uncontaminated territory was measured by instrumental neutron activation analysis and inductively coupled plasma mass spectrometry. Mean values (M  SΕΜ) for the mass fraction of U in prostate of all subjects taken together was 0.0049 ± 0.0014 mg/kg of dry tissue. In order to estimate the effect of age on the investigated parameter we used three age groups: 13-20 years, 21-40 years, and 41-60 year. Mean values (M  SΕΜ) for the mass fraction of U (mg/kg of dry tissue) in age groups were as follows: 0.0023 ± 0.0007, 0.0021 ± 0.0005, and 0.0077 ± 0.0026, respectively. For the first time statistically significant (p ï‚£ 0.05, t- test) and exponential increase of the U content in
Obsidian ; Prehistoric Central Europe ; Prehistoric Eastern Europe ; Trace element characterization ; Neutron activation analysis ; Zemplen Mountains, North Eastern Hungary ; Mousterian period ; Neolithic and Copper and Bronze Ages
Thermo Fisher Scientific announced the immediate availability of its new software, Thermo Scientific AccuLINK. This latest software offering provides cement manufacturers with a fully automatic means of continuously comparing the analysis values from an online prompt gamma neutron activation analysis (PGNAA) analyzer with laboratory x-ray fluorescence (XRF) analyses, ensuring unparalleled online accuracy and consistent and reliable calibrations. AccuLINK provides statistical and graphical data analysis so that operators and QC managers can ensure calibration adjustments are appropriate. Additionally, AccuLINK software automatically stores all performance and calibration data for future auditing, trending, and review. Having this new link assures our cement customers that their online system is performing just like their laboratory system and helps ensure that their kiln feed chemistry will be more consistent, said Jon Culbertson, global sales director and North American service manager, Thermo ...
The concentrations of I-129 and the ratios of I-129/I-127 in normal human thyroids collected in Tianjin, China, and some seaweed samples from the Chinese coast were determined by neutron activation analysis. The mean I-129/I-127 ratio in these thyroids was found to be 1.13 x 10(-9), which is two orders of magnitude higher than the level of the pre-nuclear era, but one order of magnitude lower than the level in Europe in the post-nuclear era. There is no significant difference between the ratio of I-129/I-127 in the thyroids for the post-nuclear era from China and other areas, which are considered not to have been directly exposed to 129I emission from a nuclear source, such as Chile, Taiwan and Tokyo. The mean I-129/I-127 ratio in seaweed from the Chinese coast is 2.35 x 10(-10), approximately two orders of magnitude higher than in seaweed collected in the pre-nuclear age, and similar to that from locations without direct exposure to the emission from nuclear installations, influenced only by ...
UWFDM-882 Pulsed/Intermittent Activation in Fusion Energy Reactor Systems; J.E. Sisolak, S.E. Spangler, D.L. Henderson, March 1992 [Prepared for the 10th Topical Meeting on the Technology of Fusion Energy, 7-12 June 1992, Boston MA (Fus. Tech. 21 (May 1992) 2145]. (10 pages, 592 kB) UWFDM-997 Qualitative Analysis of Physical and Mathematical Approximations Necessary for Induced Radioactivity Calculations in Fusion Devices; P.P.H. Wilson and D.L. Henderson, November 1995 [To be published in Fusion Engineering and Design]. (20 pages, 1.5 MB) UWFDM-980 RACC-Pulse: A Version of the RACC Radioactivity Code for Pulsed/Intermittent Activation Analysis; Q. Wang and D.L. Henderson, May 1995. (25 pages, 756 kB) UWFDM-628 Radioactivity in the Light Ion Fusion Target Development Facility; D.L. Henderson, R.R. Peterson, and G.A. Moses, February 1985 [Presented at the Sixth Topical Meeting on the Technology of Fusion Energy, San Francisco, CA, 3-7 March 1985; Fusion Tech. 8, (July 1985) 1396]. (9 pages, 809 ...
In July, 2012, four researchers at Ryerson University in Toronto, Canada, published a study in Bone entitled: Monitoring bone strontium levels of an osteoporotic subject due to self-administration of strontium citrate with a novel diagnostic tool, in vivo XRF: a case study. This study is significant because it used a non-invasive method (not an invasive method, such as bone biopsy) to analyze the strontium levels of bones in an osteoporotic patient who began taking strontium citrate for the study. Therefore, it was possible to obtain her baseline bone strontium levels prior to initiation of therapy with strontium citrate. The researchers wrote: By 120 hours, the increase (in bone strontium level) was statistically significant at 0.68 ± 0.07 and 0.93 ± 0.05 (for the finger and ankle), respectively. Further increases occurred within an interval of 90-180 days, with the most recent, after 800 days, at the finger and ankle being 7 and 15 times higher than the initial baseline reading. The ...
In July, 2012, four researchers at Ryerson University in Toronto, Canada, published a study in Bone entitled: Monitoring bone strontium levels of an osteoporotic subject due to self-administration of strontium citrate with a novel diagnostic tool, in vivo XRF: a case study. This study is significant because it used a non-invasive method (not an invasive method, such as bone biopsy) to analyze the strontium levels of bones in an osteoporotic patient who began taking strontium citrate for the study. Therefore, it was possible to obtain her baseline bone strontium levels prior to initiation of therapy with strontium citrate. The researchers wrote: By 120 hours, the increase (in bone strontium level) was statistically significant at 0.68 ± 0.07 and 0.93 ± 0.05 (for the finger and ankle), respectively. Further increases occurred within an interval of 90-180 days, with the most recent, after 800 days, at the finger and ankle being 7 and 15 times higher than the initial baseline reading. The ...
Carbon-14 (radiocarbon, 14C) is a long-lived radionuclide (5730 yr) of interest regarding the safety for the management of intermediate level wastes (ILW). The present study gives an overview of the release of 14C from irradiated Zircaloy cladding in alkaline media. 14C is found either in the alloy part of Zircaloy cladding due to the neutron activation of 14N impurities by 14N(n,p)14C reaction, or in the oxide layer (ZrO2) formed at the metal surface by the neutron activation of 17O from UO2 or (U-Pu)O2 fuel and water from the primary circuit in the reactor by 17O(n,α)14C reaction. Various irradiated and unirradiated Zircaloys have been studied. The total 14C inventory has been determined both experimentally and by calculations. The results seem to be in good agreement. Leaching experiments were conducted in alkaline media for several time durations. 14C was mainly released as carboxylic acids. Further, corrosion measurements were performed by using both hydrogen measurements and ...
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Phosphorus even works in our bodies to efficiently use carbohydrates and fat. Phosphorus is a dietary Gal Friday...wearing a dozen hats and ensuring that essential functions go off without a hitch.. Phosphorus is the second most abundant mineral in our bodies (calcium is the first). Luckily, phosphorus is found naturally in many food sources. Its prevalence is highest in animal products (fish, chicken and beef), but it can also be found in milk products, peanuts, tofu and soybeans. The recommended daily phosphorus intake for a healthy adult is about 700mg/day, and if youre meeting your daily protein requirements, chances are youre stocked up on phosphorus too.. Perhaps counterintuitively, the concern we need to have with phosphorus is that we may on occasion get too much. While the RDA is 700mg, the upper limit of daily phosphorus is 4,000mg/day. Thats a huge disparity, and it would be tough to eat that much protein in a single day to account for 4,000mg of phosphorus. The way you quadruple ...
Worried about your caffeine intake interfering with your bodys calcium absorption? Caffeine can slightly reduce calcium absorption, but this is significant only if you arent consuming adequate calcium.
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is defined, this macro expands to nothing. By default, the macro expands to const. The macro can be used in place of const for functions that return a value that should not be modified. The purpose of this macro is to allow us to turn on const for returned constant strings by default, while allowing programmers who find that annoying to turn it off. This macro should only be used for return values and for out parameters, it doesnt make sense for in parameters.. ...
In Access desktop databases, if you have set your document window options to use overlapping windows instead of tabbed documents, you can use the MoveAndSizeWindow macro action to move or resize the active window.
Excel & tiedonsyöttö Projects for $10 - $30. I have two files: 1) Export File 2) Formatted Export File I need a Macro that will take the exported file, and automatically format it to look like I need it to. I will provide a list of the formatti...
I have an excel file with two sheets: Contents of the first sheet: Column 1 Column 2 Column 3 Column 4 a 45 33 5423 d 66 66 4 f 2 2 1 g 2 2 3 s 33 3 2 Contents of the second sheet: Column 1 Column...
... and neutron activation analysis. Inductively coupled plasma-atomic emission spectroscopy (ICP-AES) is used for zinc ... of zinc in urine samples requires extraction of the metals with a polydithiocarbamate resin prior to digestion and analysis ( ...
Activation kinetics are unaffected by RNA editing.[11] Changes in inactivation kinetics affect the duration and frequency of ... This was determined by electrophysiology analysis.[14] The length of time the membrane is depolarised is decreased, which also ... "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A ... "Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymia". Neurogenetics. 8 (2): 131-5. doi ...
... the Journal of the Experimental Analysis of Behavior, the Journal of Applied Behavior Analysis, Division 25 of the APA, the ... Behavioral activation. ... Analysis of Verbal Behavior, the Cambridge Center for ... After his death, a memorial was held in San Francisco by the Association for Behavior Analysis, in which over two hundred ... In addition to providing a course that initiated the first use of experimental analysis of behavior during his time at Columbia ...
platelet activation. • Fc-epsilon receptor signaling pathway. • cellular response to mechanical stimulus. • phagocytosis, ... 1i4l: CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41) ... Di-Poï N, Fauré J, Grizot S, Molnár G, Pick E, Dagher MC (Aug 2001). "Mechanism of NADPH oxidase activation by the Rac/Rho-GDI ... Yang WH, Lan HY, Huang CH, Tai SK, Tzeng CH, Kao SY, Wu KJ, Hung MC, Yang MH (Apr 2012). "RAC1 activation mediates Twist1- ...
"Neutron-Activation Analysis". Karws.gso.uri.edu. Archived from the original on 2010-05-20. Retrieved 2010-08-03. Rahn, K. A.; ... see section on neutron activation analysis). This "single bullet," which was full metal jacketed and specifically designed to ... According to the analysis done by the HSCA, the horizontal angle from the 6th floor window of the Texas School Book Depository ... D. M. Green, "Analysis of Earwitness Reports Relating to the Assassination of President John F. Kennedy", Report No. 4034, 8 ...
1990). "Serum amyloid A, an acute phase protein, inhibits platelet activation". J. Lab. Clin. Med. 116 (2): 180-6. PMID 1697614 ... Five different variants from one individual demonstrated by cDNA sequence analysis". Biochem. J. 268 (1): 187-93. doi:10.1042/ ... mapping to chromosome 11p15.1 by physical and genetic linkage analysis". Genomics. 19 (2): 221-7. doi:10.1006/geno.1994.1051. ...
Activation analysis is one of the most sensitive and versatile techniques possible for elemental analysis. The technique ... Activation Analysis". In Alfassi, Zeev B. (ed.). Instrumental Multi-element Chemical Analysis. Dordrecht: Kluwer. p. 93. ... In a second type, Neutron activation analysis (NAA), a stream of neutrons generated in a particle accelerator is directed onto ... "activation analysis." The general method exploits two natural phenomena: the tendency to form stable atoms with a given energy ...
nitrogen catabolite activation of transcription from RNA polymerase II promoter. • negative regulation of tumor necrosis factor ... 1osh: A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR ... One of the primary functions of FXR activation is the suppression of cholesterol 7 alpha-hydroxylase (CYP7A1), the rate- ... 1osv: STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR ...
"Biochemical analysis of the regulatory T cell protein lymphocyte activation gene-3 (LAG-3; CD223)". Journal of Immunology. 173 ... "Entrez Gene: LAG3 lymphocyte-activation gene 3".. *^ a b c Triebel F, Jitsukawa S, Baixeras E, Roman-Roman S, Genevee C, Viegas ... with this LAG3 contributing to APC activation.[42] In August 2002 the first phenotypic analysis of the murine LAG-3 was ... molecular analysis of the negative regulatory function of lymphocyte activation gene-3". Journal of Immunology. 169 (10): 5392- ...
Katsafanas, GC; Schirmer, EC; Wyatt, LS; Frenkel, N (1996). "In vitro activation of human herpesviruses 6 and 7 from latency" ( ... Nicholas, John (September 1996). "Determination and analysis of the complete nucleotide sequence of human herpesvirus 7" (PDF ... "Metagenomic analysis of double-stranded DNA viruses in healthy adults". BMC Biology. 12: 71. doi:10.1186/s12915-014-0071-7. ... A 2014 Washington University School of Medicine's analysis of 102 healthy adults sampled at as many as five major body habitats ...
Display of activation foci. Generation of flat, inflated, spherical surfaces. Mapping of fMRI volumes onto surfaces. Surface ... Image of CARET main window with functional and foci data on surface Analysis of group anatomical differences using sulcal depth ... CARET (Computerized Anatomical Reconstruction Toolkit) is a software application for the structural and functional analysis of ...
Neutron activation analysis can be used to remotely detect the chemical composition of materials. This is because different ... Prompt Gamma-ray Neutron Activation Analysis. International Atomic Energy Agency D. Franklin; R. B. Adamson (1 January 1984). ...
WGA dubbed Windows Activation Technologies with Windows 7 "Ubuntu Linux Validates As Genuine Windows". Slashdot. 2007-06-18. ... Analysis, Comments and Product Reviews for IT Professionals The Ed Bott Report , Page 221 , ZDNet Dvorak, John C. (October 16, ... In Windows 7, WGA is renamed Windows Activation Technologies. Despite its name it does not actually evaluate the integrity or ... Office Genuine Advantage Windows Product Activation Digital rights management "The Windows Genuine Advantage (WGA) validation ...
da Silva Correia J, Miranda Y, Leonard N, Ulevitch R (April 2007). "SGT1 is essential for Nod1 activation". Proceedings of the ... "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology ...
Pulsed Fast Thermal Neutron Activation), the prompt gamma neutron activation analysis (PGNAA) and Laser-induced breakdown ... "Prompt gamma neutron activation analysis (PGNAA)." The Cement Plant Operations Handbook. Fifth ed. October 2007. Berg, Joel L ... The technology most frequently found in bulk material analysis and coal analysis are PFTNA ( ... Capitalizing on the unique gamma ray spectrum associated with each element, the instrument can perform an analysis each minute ...
February 2014). "Transcriptome-based network analysis reveals a spectrum model of human macrophage activation". Immunity. 40 (2 ... M1-activation in vitro is evoked by treatment with TLR ligands such as bacterial lipopolysaccharide (LPS) - typical for Gram- ... The M2b macrophages produce IL-1, IL-6, IL-10, TNF-𝛼 as a response to immune complexes or LPS, leading to activation of Th2 ... Macrophage activation spectrum is thus considered to be wider, involving complex regulatory pathway to response to plethora of ...
Modern Genetic Analysis - via NCBI. Busby, Steve; Ebright, Richard H (1999-10-22). "Transcription activation by catabolite ... Activation domains also come in a variety of types that are categorized based on the domain's amino acid sequence, including ... The breakdown of maltose in Escherichia coli is controlled by gene activation. The genes that code for the enzymes responsible ... "activation domain". Most activators function by binding sequence-specifically to a regulatory DNA site located near a promoter ...
After activation, LysRS is phosphorylated on Serine 207 in a MAPK-dependent manner. This phosphorylation causes LysRS to change ... Although hUBC9 is known to act preferentially with SENTRIN/SUMO1, an in vitro analysis demonstrated greater actual association ... Activation of the LysRS-Ap4A-MITF signalling pathway by isoproterenol has been confirmed in cardiomyocytes. A heart specific ... Activation of this cis-regulatory sequences by DDX3X promotes MITF expression in melanoma cells. Microphthalmia Splashed white ...
During 1936, he invented Neutron Activation Analysis. During 1943 he was domiciled in Stockholm and was an Associate of the ...
Meinke, W. W.; Anderson, R. E. (1954). "Activation Analysis of Several Rare Earth Elements". Analytical Chemistry. 26 (5): 907- ... A larger amount of 154Eu is produced by neutron activation of a significant portion of the non-radioactive 153Eu; however, much ...
A.C. O'Connor & R.J. Loomis (March 2002). Economic Analysis of Role-Based Access Control (PDF). Research Triangle Institute. p ... A multi-domain role activation model (PDF). ICC 2017 2017 IEEE International Conference on Communications. IEEE Press. pp. 1-6 ...
Performs security monitoring, security and data/logs analysis, and forensic analysis, to detect security incidents, and mounts ... A multi-domain role activation model (PDF). ICC 2017 2017 IEEE International Conference on Communications. IEEE Press. pp. 1-6 ... "Analysis , The Cybersecurity 202: Agencies struggling with basic cybersecurity despite Trump's pledge to prioritize it". The ... A.C. O'Connor & R.J. Loomis (March 2002). Economic Analysis of Role-Based Access Control (PDF). Research Triangle Institute. p ...
Neutron activation analysis, a nuclear process used for determining the concentrations of elements in materials ...
The bioelectrical impedance analysis (BIA) method is a lower-cost (from less than one to several hundred US dollars in 2006[12] ... In-vivo neutron activation can quantify all the elements of the body and use mathematical relations among the measured elements ... Siri WE (1961). "Body composition from fluid spaces and density: Analysis of methods". In Brozek J, Henzchel A (eds.). ... Brozek J, Grande F, Anderson JT, Keys A (September 1963). "Densitometric analysis of body composition: revision of some ...
Fazio, R. H., Sanbonmatsu, D. M., Powell, M. C., & Kardes, F. R. (1986). On the automatic activation of attitudes. Journal of ... Data re-analysis and commentary on Bargh, Chaiken, Govender, and Pratto (1992). Journal of Personality and Social Psychology, ... Fazio, R. H., Sanbonmatsu, D. M., Powell, M. C., & Kardes, F. R. (1986). On the automatic activation of attitudes. Journal of ... Fazio, R; Jackson, J.R.; Dunton, B.C.; Williams, C.J. (1995). "Variability in automatic activation as an unobtrusive measure of ...
After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and ... Available sequence data analyses indicate splice variants that encode different isoforms. Carboxypeptidase B GRCh38: Ensembl ... Mosnier LO, Meijers JC, Bouma BN (2002). "The role of protein S in the activation of thrombin activatable fibrinolysis ... 1997). "The gene for human carboxypeptidase U (CPU)--a proposed novel regulator of plasminogen activation--maps to 13q14.11". ...
Young KC, Shi GY, Wu DH, Chang LC, Chang BI, Ou CP, Wu HL (January 1998). "Plasminogen activation by streptokinase via a unique ... Mundada LV, Prorok M, DeFord ME, Figuera M, Castellino FJ, Fay WP (July 2003). "Structure-function analysis of the ... Wang H, Lottenberg R, Boyle MD (March 1995). "Analysis of the interaction of group A streptococci with fibrinogen, ... The usual activation of plasminogen is by proteolysis of the Arg561-Val562 bond. The amino group of Val562 then forms a salt- ...
Wayman, Michael L. (1989). Neutron Activation Analysis of Metals: A Case Study. MASCA Research Papers in Science and ...
Reuter CW, Catling AD, Jelinek T, Weber MJ (March 1995). "Biochemical analysis of MEK activation in NIH3T3 fibroblasts. ... It then binds key activation loop and DFG motif residues to stop the movement of the activation loop and DFG motif to the ... During B-Raf activation, the protein's autoinhibitory CR1 domain first binds Ras-GTP's effector domain to the CR1 Ras-binding ... "Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF". Cell. 116 (6): 855-67. doi:10.1016/ ...
H. J. Born Activation analysis, Technical Report Number BMBW-FBK-72-13, 1st Seminar on Activation Analysis, 8 December 1970, ... 1, 29-43 (1973) H. J. Born and J. L. Kim Monostandard activation analysis and its applications: analyses of kale powder and NBS ... P. Wilkniss and H. J. Born On the Activation Analysis of Oxygen with Help of the Reaction O16 (T,n) F18, Intern. J. Appl. ... H. J. Born and D. C. Aumann Activation Analysis Determination of Lithium with the Help of the Reaction Chain 6Li (n,d) 3H and ...
Activation of FXR in the liver inhibits synthesis of bile acids, and is one mechanism of feedback control when bile acid levels ... a meta-analysis". Obes Surg. 18 (12): 1532-8. doi:10.1007/s11695-008-9587-7. PMID 18574646. S2CID 207302960.. ... Secondly, FXR activation by bile acids during absorption in the intestine increases transcription and synthesis of FGF19, which ... Emerging evidence associates FXR activation with alterations in triglyceride metabolism, glucose metabolism, and liver growth.[ ...
... carbohydrate recognition and analysis of the b-prims fold". Protein Science. 8 (1): 13-24. doi:10.1110/ps.8.1.13. PMC 2144112. ... "Tyrosine 151 is part of the substrate activation binding site of bovine trypsin: identification by covalent labelling with p- ...
The meta-analysis showed greater muscle mass gain in the intervention groups compared with the control groups (standard mean ... During atrophy, there is a down-regulation of protein synthesis pathways, and an activation of protein degradation. The ... Based upon a meta-analysis of seven randomized controlled trials that was published in 2015, HMB supplementation has efficacy ... The studies included in the meta-analysis had durations of 2-12 months and the majority of studies lasted 2-3 months. Seene T ( ...
Three-dimensional images of tracer concentration within the body are then constructed by computer analysis. In modern PET ... One of the main advantages of using PET is that it can also provide muscle activation data about deeper lying muscles such as ... 2002). "Brain imaging of 18F-fallypride in normal volunteers: Blood analysis, distribution, test-retest studies, and ... A clear disadvantage is that PET provides no timing information about muscle activation because it has to be measured after the ...
This enables the virus to evade the immune system by inhibiting early steps of neutrophil activation.[medical citation needed] ... "Virological Analysis: no link between Ebola outbreaks in west Africa and Democratic Republic of Congo". World Health ... an analysis of Ebola virus RNA results and behavioural data". Lancet Global Health. 4 (10): e736-e743. doi:10.1016/S2214-109X( ... On TLR activation, proteins including interferon regulatory factor 3 and interferon regulatory factor 7 trigger a signalling ...
... a systematic review and meta-analysis". The British Journal of Dermatology (Systematic Review & Meta-Analysis). 173 (5): 1132- ... Activation of TLR2 and TLR4 by C. acnes leads to increased secretion of IL-1α, IL-8, and TNF-α.[45] The release of these ... "Journal of Zhejiang University Science B (Meta-analysis). 13 (3): 192-202. doi:10.1631/jzus.B1100285. PMC 3296070. PMID ... "Annals of Family Medicine (Systematic Review & Meta-Analysis). 17 (6): 545-553. doi:10.1370/afm.2445. PMC 6846280. PMID ...
PML is caused by activation of JC virus, a common virus in the brain which is usually latent. Reactivation of the JC virus ... "Treatment of neuromyelitis optica with rituximab: retrospective analysis of 25 patients". Arch Neurol. 65 (11): 1443-1448. doi ... maintaining intracellular Ca2+ concentration and allowing activation of B cells. ...
Mandler, G. & Shebo, B.J. (1982). "Subitizing: An analysis of its component processes". Journal of Experimental Psychology: ... This has been interpreted as evidence that shared processes are involved.[19] However, the existence of further activations ... Corbetta, M.; Shulman, G.L.; Miezin, F.M. & Petersen, S.E. (1995). "Superior parietal cortex activation during spatial ... Such research finds that within the subitizing and counting range activation occurs bilaterally in the occipital extrastriate ...
PML is caused by activation of JC virus, a common virus in the brain which is usually latent. Reactivation of the JC virus ... Kriston, Levente (2009). "Challenges in Reporting Meta-analyses of Diagnostic Accuracy Studies". Annals of Internal Medicine. ... maintaining intracellular Ca2+ concentration and allowing activation of B cells. ... "Treatment of neuromyelitis optica with rituximab: retrospective analysis of 25 patients". Arch Neurol. 65 (11): 1443-1448. doi ...
... as it orchestrates activation of cell cycle subsystems and Caulobacter crescentus asymmetric cell division. The proteins of the ... "The diversity and evolution of cell cycle regulation in alpha-proteobacteria: A comparative genomic analysis". BMC Systems ...
Activation of normal PPARy targets due to the over expression of the chimeric protein that contain all functional domains of ... "A comprehensive analysis of PAX8 expression in human epithelial tumors". The American Journal of Surgical Pathology. 35 (6): ... Re-activation of PAX8 (or Pax2) expression has been reported in pediatric Wilms Tumors, almost all subtypes of renal cell ... Activation of a set of genes unrelated to both wild-type PPARy and wild-type PAX8 pathways ...
Job Analysis of Chiropractic (PDF). Greeley, CO: National Board of Chiropractic Examiners. pp. 121-38. ISBN 1-884457-05-3. ... depending on duration and amplitude of the thrust are factors of the degree in paraspinal muscle spindles activation.[74] ... Analysis of a clinical and cost utilization data from the years 2003 to 2005 by an integrative medicine independent physician ... A 2011 systematic review and meta-analysis concluded that the addition of manual mobilizations to an exercise program for the ...
A Brdu analysis showed that excess testosterone did not increase this blocking effect against social isolation; that is, the ... Researchers also examined how mild exercise affected androgen synthesis which in turn causes AHN activation of N-methyl-D- ... Analysis showed that testosterone and dihydrotestosterone regulated adult hippocampal neurogenesis (AHN). Adult hippocampal ... Again it was noted that AHN was not increase via activation of the estrogen receptors.[13] ...
"Chemical risk analysis: a practical handbook. p. 215. ISBN 978-1-903996-65-2. .. ... This quantity decreases going down the group, and so does the activation energy; thus, chemical reactions can occur faster and ... Adding the atomisation and first ionisation energies gives a quantity closely related to (but not equal to) the activation ... MacPherson, H. G. (1934). "An Investigation of the Magneto-Optic Method of Chemical Analysis". Physical Review. American ...
The early Cubist explorations of Picasso were to uncover other aspects in the work of El Greco: structural analysis of his ... the process for the activation of the painterly values of El Greco which had been started by Manet and carried on by Cézanne".[ ... Comparative morphological analyses of the two painters revealed their common elements, such as the distortion of the human body ...
"Muscle Activation of Paraspinal Muscles in Different Types of High Heels during Standing." Journal of Physical Therapy Science ... An analysis of the dance-related injuries in 113,084 adolescents in US emergency rooms from 1991-2007 was conducted using data ... The results of the study indicated an increase in both cervical and lumbar muscle activation as heel height increased. The ... researchers wanted to investigate the effects of high heels on the activation of muscles in the cervical and lumbar portions of ...
Ishizuka O, Nishizawa O, Hirao Y, Ohshima S (2002). "Evidence-based meta-analysis of pharmacotherapy for benign prostatic ... induced release of gonadotropins and consequent activation of gonadal androgen production.[2][64] Examples include GnRH ... a meta-analysis of published randomized controlled trials using nonsteroidal antiandrogens". Urology. 49 (1): 71-8. doi:10.1016 ... AR NTD antagonists bind covalently to the NTD of the AR and prevent protein-protein interactions subsequent to activation that ...
a b c Paul, K. I., & Moser, K. (2009). Unemployment impairs mental health: Meta-analyses. Journal of Vocational Behavior, 74, ... rewards triggers high levels of activation in neurohormonal pathways that, cumulatively, are thought to exert adverse effects ... Meta-analyses have been used to aggregate data (modern approaches to meta-analyses rely on HLM), and draw conclusions across ... a b Raudenbush, S.W., & Bryk, A.S. (2001). Hierarchical linear models: Applications and data analysis methods (2nd ed.). ...
Wilson, R.H.; Bray, J.W.; Kosky, P.G.; Vakil, H.B.; Will, F.G. (1992), "Analysis of experiments on the calorimetry of LiOD-D2O ... Cold fusion setups utilize an input power source (to ostensibly provide activation energy), a platinum group electrode, a ... 2, pp.85-93 and "Atomic Structure Analysis of Pd Nano-Cluster in Nano-Composite Pd⁄ZrO2 Absorbing Deuterium" - Journal of High ... Miskelly, GM; Heben MJ; Kumar A; Penner RM; Sailor MJ; Lewis NL (1989), "Analysis of the Published Calorimetric Evidence for ...
... and the role of the smart wheelchair is to interpret small muscular activations as high-level commands and execute them. Such ... "Kinetic and physiological analysis of the GameWheels system". JRRD. 39 (6): 627-34. ISSN 0748-7711 ...
... functional magnetic resonance imaging with specialized multivariate analyses to study the temporal dimension in the activation ... The first part of their analysis (which the only relevant part to this section) was not meant to discover the types of free ... Without entering into metaphysical speculations, I may perhaps add that an analysis of the very concept of explanation would, ... More sophisticated analyses of compatibilist free will have been offered, as have other critiques.[110] ...
The pharmacodynamic action encompasses activation, elevation of mood, and improvement of symptoms like dysphoria, fatigue, and ... Angst, J; Amrein, R; Stabl, M (August 1995). "Moclobemide and tricyclic antidepressants in severe depression: meta-analysis and ... a meta-analysis of moclobemide studies". J Affect Disord. 35 (1-2): 21-30. doi:10.1016/0165-0327(95)00034-K. PMID 8557884.. ... Ghanbarpour A, Hadizadeh F, Piri F, Rashidi-Ranjbar P (April 1997). "Synthesis, conformational analysis and antidepressant ...
Music Therapists use lyric analysis in a variety of ways, but typically lyric analysis is used to facilitate dialogue with ... While results are somewhat contradictory, studies have in fact found increased right hemispheric activation in non-fluent ... A 2016 meta-analysis on the effects of music therapy in schizophrenic patients showed that the treatment in patients who ... Though lyric analysis is often and widely used, research that compares music therapy intervention has been inconclusive up to ...
"Analysis of essential elements in Pragya-peya-a herbal drink and its constituents by neutron activation". Journal of ... Pittler MH, Ernst E (2000). "Efficacy of kava extract for treating anxiety: systematic review and meta-analysis". Journal of ... Pharmaceutical and Biomedical Analysis. 37 (4): 631-828. doi:10.1016/j.jpba.2004.11.051. PMID 15797781.. ...
Nasuto, S.J., Bishop, J.M. & Lauria, S., Time complexity analysis of the Stochastic Diffusion Search, Proc. Neural Computation ... "Pattern Activation/Recognition Theory of Mind". Frontiers in Computational Neuroscience. 9 (90). doi:10.3389/fncom.2015.00090 ... microscopic derivation and stability analysis". J. Phys. A. 42 (44): 445001. arXiv:0907.4688 . Bibcode:2009JPhA...42R5001B. doi ...
Transactional analysis. *Transference focused psychotherapy. *Transpersonal psychology. *Transtheoretical model (TTM or "stages ... Behavioral activation. *Behavior modification. *Behavior therapy. *Bibliotherapy. *Biodynamic psychotherapy. *Bioenergetic ...
Kazerouni, N; Sinha, R; Hsu, CH; Greenberg, A; Rothman, N (2002). "Analysis of 200 food items for benzo[a]pyrene and estimation ... Stribinskis, Vilius; Ramos, Kenneth S. (2006). "Activation of Human Long Interspersed Nuclear Element 1 Retrotransposition by ... Kleiböhmer, W. (2001). "Polycyclic Aromatic Hydrocarbon (PAH) Metabolites". Environmental Analysis (Volume 3 of Handbook of ...
Arnott, S., Thaler, L., Milne, J., Kish, D., & Goodale, M. (n.d). Shape-specific activation of occipital cortex in an early ... a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545-1602. doi:10.1016/S0140-6736(16) ...
Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, Jones PA (2006). "Specific activation of microRNA-127 with ... Sarkisian CJ, Master SR, Huber LJ, Ha SI, Chodosh LA (Oct 2001). "Analysis of murine Brca2 reveals conservation of protein- ... "RAD51 localization and activation following DNA damage". Philosophical Transactions of the Royal Society of London. Series B, ...
Liu WS, Soldatov NM, Gustavsson I, Chowdhary BP (1999). "Fiber-FISH analysis of the 3'-terminal region of the human L-type Ca2+ ... These activation and inactivation mechanisms both involve Ca2+ binding to calmodulin (CaM) in the IQ domain in the C-terminal ... Large-scale genetic analyses have shown the possibility that CACNA1C is associated with bipolar disorder [21] and subsequently ... "Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder". Nature Genetics. 40 ...
Single-molecule imaging analysis of Ras activation in living cells. Hideji Murakoshi, Ryota Iino, Takeshi Kobayashi, Takahiro ... Single-molecule imaging analysis of Ras activation in living cells. Hideji Murakoshi, Ryota Iino, Takeshi Kobayashi, Takahiro ... Single-molecule imaging analysis of Ras activation in living cells Message Subject (Your Name) has sent you a message from PNAS ... Single-molecule imaging analysis of Ras activation in living cells. Hideji Murakoshi, Ryota Iino, Takeshi Kobayashi, Takahiro ...
Proteomic analysis of microtubule-associated proteins during macrophage activation.. Patel PC1, Fisher KH, Yang EC, Deane CM, ... Proteomic Analysis of Microtubule-associated Proteins during Macrophage Activation. Mol Cell Proteomics. 2009 Nov;8(11):2500- ... Proteomic Analysis of Microtubule-associated Proteins during Macrophage Activation. Mol Cell Proteomics. 2009 Nov;8(11):2500- ... Proteomic Analysis of Microtubule-associated Proteins during Macrophage Activation. Mol Cell Proteomics. 2009 Nov;8(11):2500- ...
Neutron activation analysis is used to measure bromide so that extraction is not necessary for analysis. NAA is used in geology ... this technique is known as Radiochemical Neutron Activation Analysis (RNAA). NAA can perform non-destructive analyses on solids ... Neutron activation analysis (NAA) is the nuclear process used for determining the concentrations of elements in a vast amount ... Neutron activation analysis is also used to create standards in the semiconductor industry. Semiconductors require a high level ...
The method of activation analysis not only increases the sensitivity for many trace elements1 but also eliminates the necessity ... for running blank analyses on the reagents since small amounts of impurities contained in the reagents will not be measured. ... Some Activation Analyses of Six Trace Elements in Marine Biological Ashes. *R. FUKAI1. ,2. nAff2 & ... The method of activation analysis not only increases the sensitivity for many trace elements1 but also eliminates the necessity ...
Data base analysis of protein expression patterns during T-cell ontogeny and activation.. S M Hanash, J R Strahler, Y Chan, R ... Data base analysis of protein expression patterns during T-cell ontogeny and activation. ... Data base analysis of protein expression patterns during T-cell ontogeny and activation. ... Data base analysis of protein expression patterns during T-cell ontogeny and activation. ...
Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway.. Lou H1, Villagran G2, Boland JF3 ... Analysis of 675 tumors revealed activation of PIK3CA and other PI3K/AKT pathway genes in 31% of squamous carcinomas and 24% of ... Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway ... Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway ...
Prompt-gamma neutron activation analysis (PGAA) is a very widely applicable technique for determining the presence and amount ... Harder, J. 2009, Material analysis for process control in cement plants, ZKG INTERNATIONAL, 6/7 - 2009, Volume 62, p. 64 http ...
... Tumour Biol. 2014 Jun;35(6 ... and with IDH1-R132H mutation were examined by global metabolome analysis using capillary electrophoresis time-of-flight mass ...
Analysis of Posttranslational Activation of Alternative Oxidase Isoforms. Jennifer Selinski, Andreas Hartmann, Adrian Kordes, ... Analysis of Posttranslational Activation of Alternative Oxidase Isoforms. Jennifer Selinski, Andreas Hartmann, Adrian Kordes, ... Analysis of Posttranslational Activation of Alternative Oxidase Isoforms Message Subject (Your Name) has sent you a message ... Analysis of Posttranslational Activation of Alternative Oxidase Isoforms. Jennifer Selinski, Andreas Hartmann, Adrian Kordes, ...
... PLoS One. 2008 Feb 20;3(2):e1628. doi: ... for the hypothesis that proteolytic cleavage of the propeptide by BMP-1/TLD proteases plays a critical role in the activation ...
on modern trends in activation analysis, Copenhagen, 1986, June 23-27 : Activation techniques ... Neutron activation analysis applied to the study of the composition of Cuban geological samples from petroleum ores [Text] : ... Proceedings of the 9th international conference on modern trends in activation analysis : MTAA-9,Sept.24-30,1995,Seoul,Korea ... Proceedings of the 9th international conference on modern trends in activation analysis : MTAA-9,Sept.24-30,1995,Seoul,Korea ...
... sup 232/Th in seawater has made possible rapid sampling and analysis of this long-lived, non-radiogenic thorium isotope on ... The recent development of neutron activation analysis and mass spectrometric methods for the determination of / ... Huh, Chih-An. Determination of thorium in seawater by neutron activation analysis and mass spectrometry, article, January 1, ... The recent development of neutron activation analysis and mass spectrometric methods for the determination of /sup 232/Th in ...
Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation.. [Stefano de Pretis, Theresia R ... Here, we present an integrated time-course analysis of transcription and mRNA dynamics following MYC activation in ... Transcriptional activation correlated with the highest increases in MYC binding at promoters. Repression followed a reciprocal ... MYC activation elicited immediate loading of RNA polymerase II (RNAPII) at activated promoters, followed by increases in pause- ...
Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. Giulia Fabbri, Silvia Rasi, ... Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation ... Genome-wide SNP analysis. Analysis of the same 5 CLL samples (and paired normal DNAs) by the Affymetrix SNP 6.0 platform ... FISH analysis.. The following probes were used for FISH analysis of CLL and RS cases: LSID13S319, CEP12, LSIp53, LSIATM, LSI ...
In the activation analysis method, molybdate and tungstate ions are added to samples containing phosphate ion to form ... After activation of an aliquot of the organic phase for 1 hour at a flux of 1013 neutrons per cm2, per second, the gamma ... If the ratio of phosphorus to sulfur or chlorine is small, as it is in most natural waters, accurate analyses by these methods ... Activation analysis may be used to determine quantitatively traces of phosphate in natural waters. Methods based on the ...
Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation ... Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation ... Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation ... Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation ...
Abstract: A5.00002 : Single molecule analysis of B cell receptor motion during signaling activation. 8:36 AM-8:48 AM ... During activation, BCR form signaling microclusters that later coalesce as the cell contracts. We have studied the dynamics of ... B cell receptor (BCR) binding to antigen induces a signaling cascade that leads to B cell activation and spreading. ... The tracks are analyzed using perturbation expectation-maximization (pEM), a systems-level analysis, which allows ...
At the same time, a novel result emerges from our analysis: the discovery of a dynamic transcritical bifurcation that exists in ... The general intermolecular mechanism for the autocatalytic activation of zymogens is governed by the single-enzyme, single- ... In this article we investigate the nonlinear chemical dynamics of the intermolecular autocatalytic zymogen activation reaction ... This is the first report of such a solution for the intermolecular and autocatalytic zymogen activation reaction. By extension ...
The activation of NEI system in shrimp hemocytes triggered by WSSV infection. After analysis of all DEGs from shrimp hemocytes ... Transcriptome analysis reveals the activation of neuroendocrine-immune system in shrimp hemocytes at the early stage of WSSV ... 5 for annotation analysis, and the best alignments were used for further analysis. The gene abundances were calculated and ... Analysis of acetylcholine and its pathway in L. vannamei Acetylcholine (ACh) is a component of the cholinergic system [74] and ...
The genetic analysis of snf: a Drosophila sex determination gene required for activation of Sex-lethal in both the germline and ... The genetic analysis of snf: a Drosophila sex determination gene required for activation of Sex-lethal in both the germline and ... The genetic analysis of snf: a Drosophila sex determination gene required for activation of Sex-lethal in both the germline and ... The genetic analysis of snf: a Drosophila sex determination gene required for activation of Sex-lethal in both the germline and ...
... are mediated by T cell activation or activation by MHC II-only, are unresolved and results are contradictory. We have addressed ... T cell activation has been assessed by lymphocyte proliferation and IL-2 gene expression after in vivo challenge with TSST-1 ... Staphylococcal Superantigen (TSST-1) Mutant Analysis Reveals that T Cell Activation Is Required for Biological Effects in the ... Staphylococcal Superantigen (TSST-1) Mutant Analysis Reveals that T Cell Activation Is Required for Biological Effects in the ...
Cutting Edge: Molecular Analysis of the Negative Regulatory Function of Lymphocyte Activation Gene-3. Creg J. Workman, Kari J. ... Cutting Edge: Molecular Analysis of the Negative Regulatory Function of Lymphocyte Activation Gene-3 ... Cutting Edge: Molecular Analysis of the Negative Regulatory Function of Lymphocyte Activation Gene-3 ... Cutting Edge: Molecular Analysis of the Negative Regulatory Function of Lymphocyte Activation Gene-3 ...
Systems-Level Analysis of Proteolytic Events in Increased Vascular Permeability and Complement Activation in Skin Inflammation ... Systems-Level Analysis of Proteolytic Events in Increased Vascular Permeability and Complement Activation in Skin Inflammation ... Systems-Level Analysis of Proteolytic Events in Increased Vascular Permeability and Complement Activation in Skin Inflammation ... Systems-Level Analysis of Proteolytic Events in Increased Vascular Permeability and Complement Activation in Skin Inflammation ...
"Activation Analysis" by people in this website by year, and whether "Activation Analysis" was a major or minor topic of these ... "Activation Analysis" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Activation Analysis" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Activation Analysis". ...
The activations elicited by these stimuli, each relative to a matched control, overlapped substantially in the group analysis. ... Here we applied this technique to the analysis of overlapping activations in the LOTC. The main approach of this study was as ... Pattern analyses. Combined ROIs. Pattern analyses were applied to a general region of the LOTC, defined in each subject by the ... Whole-brain analysis.. Whole-brain random-effects, group-average analyses were conducted on data from all four experiments. ...
Northern and 5′ RACE analysis of long-distance activation.To assay long-distance activation at the transcriptional level and to ... Analysis of Transcriptional Activation at a Distance in Saccharomyces cerevisiae Krista C. Dobi, Fred Winston ... Analysis of Transcriptional Activation at a Distance in Saccharomyces cerevisiae Message Subject (Your Name) has forwarded a ... Phenotypic analyses of mutants permissive for long-distance activation. (A) Growth of mutant strains with the HIS3 UAS 799 ...
In this study, we evaluated different advanced CID techniques (i.e., neutral-loss triggered MS3 and multi-stage activation) ... Overall, the multi-stage activation approach produced more glycated peptide identifications, while the neutral-loss triggered ... during LC-MSn analyses of Amadori-modified peptides enriched from human serum glycated in vitro. During neutral-loss triggered ... neutral losses of 3 H2O resulted in significantly more glycated peptide identifications during multi-stage activation ...
Molecular Dynamics Guided Analysis of Ligand Activation, Ion Permeation and Subtype-specific Ligand Interactions in P2X ... Molecular Dynamics Guided Analysis of Ligand Activation, Ion Permeation and Subtype-specific Ligand Interactions in P2X ... Molecular Dynamics Guided Analysis of Ligand Activation, Ion Permeation and Subtype-specific Ligand Interactions in P2X ... Molecular Dynamics Guided Analysis of Ligand Activation, Ion Permeation and Subtype-specific Ligand Interactions in P2X ...
Analysis of Multiple Sarcoma Expression Datasets: Implications for Classification, Oncogenic Pathway Activation and ... Analysis of multiple sarcoma expression datasets: Implications for classification, oncogenic pathway activation and ... Bayesian models of oncogenic pathway activation and chemotherapy response were applied to individual STS samples. A 170-gene ... Different sarcoma subtypes demonstrated distinct oncogenic pathway activation patterns, and reclassified MFH tumors shared ...
  • Proteomic analysis of microtubule-associated proteins during macrophage activation. (nih.gov)
  • More detailed analysis of one up-regulated protein revealed a role for HSP90beta in stabilization of the MT cytoskeleton during macrophage activation. (nih.gov)
  • In response to stimulation across all pairs of 9 cytokine inputs, the model predicted activation along the classic M1-M2 polarization axis but also a second axis of macrophage activation that distinguishes unstimulated macrophages from a mixed phenotype induced by conflicting cues. (biorxiv.org)
  • In summary, the computational model predicts that network crosstalk mediates a broadened spectrum of macrophage activation in response to mixed pro- and anti-inflammatory cytokine cues, making it useful for modeling in vivo scenarios. (biorxiv.org)
  • Summary sentence Network modeling of macrophage activation predicts responses to combinations of cytokines along both the M1-M2 polarization axis and a second axis associated with a mixed macrophage activation phenotype. (biorxiv.org)
  • Objectives Macrophage activation syndrome (MAS) is a severe, potentially life-threatening syndrome.Here we aim to review the precipitating events,clinical features, treatment, outcome and perforin A91V gene analysis in systemic onset juvenile idiopathic arthritis (SoJIA) children with MAS. (bmj.com)
  • Therefore, the objective of this study is to analyze macrophage activation patterns post-MI. (biomedcentral.com)
  • A set of differential equations were established to characterize the regulatory relationships for macrophage activation in the left ventricle post-MI based on the physical chemistry laws. (biomedcentral.com)
  • We have established and validated a mathematical model for macrophage activation post-MI. (biomedcentral.com)
  • A large amount of experimental research has been conducted to elucidate the underlying mechanisms of macrophage activation, and an abundant accumulation of experimental results define on macrophage responses to different stimuli. (biomedcentral.com)
  • However, most models do not consider the effect of macrophage activation patterns and ignore the differences between macrophage phenotypes. (biomedcentral.com)
  • Therefore, the aim of this study was to establish and validate a set of ordinary differential equations to characterize macrophage activation patterns post-MI. (biomedcentral.com)
  • Here, we used genome‐scale modeling and multi‐omics (transcriptomics, proteomics, and metabolomics) analysis to assess metabolic features that are critical for macrophage activation. (embopress.org)
  • Finally, underlying metabolic mechanisms of macrophage activation are identified by analyzing multi‐omic data obtained from LPS‐stimulated RAW cells in the context of our flux‐based predictions. (embopress.org)
  • Genome‐scale metabolic network reconstruction and analysis of the murine leukemic macrophage cell line RAW 264.7 reveal a complementary relationship between how known metabolic immunomodulators are biochemically processed and their role in macrophage activation. (embopress.org)
  • Three levels of high‐throughput data (transcriptomic, proteomic, and metabolomic) were analyzed in the context of the model‐based predictions to elucidate underlying metabolic mechanisms of macrophage activation. (embopress.org)
  • Results suggest a potential contending link between de‐novo nucleotide synthesis and macrophage activation phenotypes at a glutamine junction. (embopress.org)
  • 2014. A hydrophobic residue in position 15 of the rP2X3 receptor slows desensitization and reveals properties beneficial for pharmacological analysis and high-throughput screening. (ukaachen.de)
  • Along this second axis, combinations of conflicting stimuli, interleukin 4 (IL4) with lipopolysaccharide (LPS), interferon-γ (IFNγ), IFNβ, or tumor necrosis factor-α (TNFα), produced mutual inhibition of several signaling pathways, e.g. nuclear factor κB (NFκB) and signal transducer and activator of transcription 6 (STAT6), but also mutual activation of the phosphoinositide 3-kinases (PI3K) signaling module. (biorxiv.org)
  • Metabolic network‐based analyses identified well‐established critical metabolite effectors and intracellular pathways that impact activation or suppression of M1‐ and M2‐metabolic activation phenotypes. (embopress.org)
  • To understand the finely tuned process of neutrophil functioning in vivo, it is also necessary to define components of the signaling pathways responsible for the priming and activation of effector functions in granulocytes. (uu.nl)
  • The aims of our study were to investigate PIK3CA gene mutations on a large series of TNBC, to perform a wider analysis on genetic alterations involving PI3K/AKT and BRAF/RAS/MAPK pathways and to correlate the results with clinical-pathologic data. (uniss.it)
  • Deregulation of PI3K/AKT pathways was revealed by consistent activation of pAKT and p-p44/42 MAPK in all PIK3CA mutated TNBC. (uniss.it)
  • Analysis of microarray data demonstrated that the transcriptome of CD4 + CD154 + cells was distinct from that of CD154 - cells and showed major enrichment of transcripts encoding multiple cytokines and pathways of cellular activation. (elsevier.com)
  • A bistable switch has recently been found to regulate the activation of transforming growth factor-β1 (TGF-β1) in the context of liver fibrosis, and an ordinary differential equation (ODE) model was published showing that the net activation of TGF-β1 depends on the balance between two antagonistic sub-pathways. (biomedcentral.com)
  • FLT3 mutations result in constitutive activation of the FLT3 receptor kinase in the absence of FLT3 ligand and abnormal activation of downstream signaling pathways, including signal transducer and activator of transcription 5 (STAT5), mitogen-activated protein kinase kinase (Mek)/extracellular signal-regulated kinase (Erk) and phosphatidylinositol-3 kinase (PI3K). (bloodjournal.org)
  • Transcriptome analysis was performed in a subset of 14 of 50 Ewing sarcomas and DNA copy number gain and expression of FGFR1 in 63 of 116 Ewing sarcomas. (uzh.ch)
  • Analysis of Ag-specific CD4 + T cells in mycobacterial infections at the transcriptome level is informative but technically challenging. (elsevier.com)
  • The activations elicited by these stimuli, each relative to a matched control, overlapped substantially in the group analysis. (jneurosci.org)
  • Lipopolysaccharide (LPS) and interferon-γ (IFNγ) are the prototypical stimuli for M1-type activation, and interleukin(IL) 4 is a prototypical M2-type stimulus. (biorxiv.org)
  • While the number of studies eligible to be included in this meta-analysis was small, the results of this systematic review reveal that antisaccade and prosaccade trials consistently activate a distributed network of regions both within and outside the classic definition of the oculomotor network. (frontiersin.org)
  • 2-14 However, RRS activation in dialysis patients has not been studied before, and we hypothesised that such an analysis might reveal unique systemic problems. (bmj.com)
  • Statistical analyses reveal a significantly asymmetric facial muscle action in subjects with ASD compared to the typically-developing controls. (3dmd.com)
  • If NAA is conducted directly on irradiated samples it is termed Instrumental Neutron Activation Analysis (INAA). (wikipedia.org)
  • Chromium concentration in samples collected from local tanners who use tannins from Acacia nilotica as tanning agent was below the detection limit of Instrumental Neutron Activation Analysis (INAA) technique used in the study. (thescipub.com)
  • k 0 -Instrumental Neutron Activation Analysis ( k 0 -INAA) offers some intrinsic quality control opportunities for the determination of the tin content in samples since several monitoring radioisotopes are formed. (springer.com)
  • Instrumental Neutron Activation Analysis (INAA) is one of the most sensitive analytical techniques used for the quantitative multi-element analysis of major, minor, and trace elements in samples from almost every conceivable field of scientific or technical interest. (ncsu.edu)
  • Analysis of 675 tumors revealed activation of PIK3CA and other PI3K/AKT pathway genes in 31% of squamous carcinomas and 24% of adeno- and adenosquamous tumors, predominantly at two sites (E542K, E545K) in the helical domain of the PIK3CA gene. (nih.gov)
  • These analyses led to the discovery of several genes not previously known to be altered in CLL. (rupress.org)
  • C57BL/6J (B6) XY gonads showed a consistent ~5-hour delay in the activation of most male pathway genes and repression of female pathway genes relative to 129S1/SvImJ, which likely explains the sensitivity of the B6 strain to male-to-female sex reversal. (sigmaaldrich.com)
  • Several approaches have been used to successfully identify genes induced by p53 including differential display, representational difference analysis, cDNA microarrays, and serial analysis of gene expression ( 3 - 6 ). (aacrjournals.org)
  • Alternatively, p53 target genes should be identifiable using an in silico analysis of p53 response elements (p53RE) as probes ( 7 ). (aacrjournals.org)
  • Results: Genes with the strongest upregulation after receptor activation were FOS-like antigen 1 (Fosl1), early growth response 1 (Egr1), osteopontin (Opn), insulin-like growth factor binding protein 3 (Igfbp3), dual-specificity phosphatase 4 (Dusp4), and tumor-associated antigen L6 (Taal6). (uni-wuerzburg.de)
  • These data are the basis for future detailed analyses of the investigated target genes. (uni-wuerzburg.de)
  • In addition several genes of the IFN signaling pathway are up-regulated, indicating a strong antiviral response and activation of the negative feedback mechanism to limit type I IFN responses. (eur.nl)
  • Many genes induced by DAG/PKC signalling are associated with processes central for T cell activation. (uta.fi)
  • We found a significant overlap in differentially expressed genes (DEGs) with genes involved in regulating the extracellular matrix, and those that are activated or inhibited when macrophages and microglia are stimulated towards the M1 and M2 activation states. (springermedizin.de)
  • Principal components analysis (PCA) was carried out on the top 5000 most variable genes as defined by the software DESeq2. (springermedizin.de)
  • The results from the present study suggest that training blunts the transcriptional upregulation of immune activation by minimizing expression of genes involved in monocyte recruitment and enhancing gene expression involved in macrophage anti-inflammatory polarization. (elsevier.com)
  • However, neutral losses of 3 H2O resulted in significantly more glycated peptide identifications during multi-stage activation experiments. (unt.edu)
  • Furthermore, the delivery of active proteases to the phagosome is significantly reduced after the activation of DCs with lipopolysaccharide. (rupress.org)
  • As predicted, hope and patient activation were significantly related with each other, showing large positive concurrent correlations. (iupui.edu)
  • Demographics and background characteristics were not significantly related to patient activation or hope. (iupui.edu)
  • All p telomeres changed their position significantly during the activation process, although the effect was less pronounced for the q telomeres. (docphin.com)
  • This analysis revealed that the distribution of pp, qq and pq associations differs significantly among the 7 chromosomes. (docphin.com)
  • 12-14 Our recent article showed that Ang II content is significantly increased in the brain, as well as in plasma, in hRN/hANG-Tg mice, and that activation of the human RAS in the brain is involved in exaggeration of ischemic brain damage attributed partly to enhancement of oxidative stress. (ahajournals.org)
  • Activation by glutamate at CysI and CysII is consistent with the formation of the thiohemiacetal, while succinate activation after changing CysI to serine suggests hemiacetal formation. (plantphysiol.org)
  • Consistent with the association of NOTCH1 mutations with clinically aggressive forms of the disease, NOTCH1 activation at CLL diagnosis emerged as an independent predictor of poor survival. (rupress.org)
  • In S. cerevisiae , evidence consistent with tracking came from experiments in which LexA binding or a transcription terminator blocked transcriptional activation ( 8 ). (asm.org)
  • We present a quantitative meta-analysis of all published voxel-wise fMRI and PET studies (18) of the antisaccade task and show that consistent activation for antisaccades and prosaccades is obtained in a fronto-subcortical-parietal network encompassing frontal and supplementary eye fields (SEFs), thalamus, striatum, and intraparietal cortex. (frontiersin.org)
  • The activation likelihood estimation (ALE) was used, which is a quantitative voxel based meta-analysis method which can be used to estimate consistent activations across different imaging studies. (bmj.com)
  • Methods The present study is a quantitative meta-analysis of the current VBM findings aimed at delineating the cortical regions with consistently increased or reduced GM concentrations. (bmj.com)
  • A voxel quantitative meta-analysis technique called activation likelihood estimation (ALE) was used.The meta-analysis included six neuroimaging studies involving 247 TS patients and 236 healthy controls. (researchsquare.com)
  • Activation likelihood estimation (ALE), a quantitative meta-analysis for imaging studies, is a statistically-based approach that we used to analyze results of grey matter volumes across studies. (researchsquare.com)
  • Is the Subject Area "Meta-analysis" applicable to this article? (plos.org)
  • AIM: To undertake a meta-analysis on the value of urinary trypsinogen activation peptide (uTAP) in predicting severity of acute pancreatitis on admission. (pubmedcentralcanada.ca)
  • RESULTS: In total, six studies of uTAP with a cut-off value of 35 nmol/L were included in this meta-analysis. (pubmedcentralcanada.ca)
  • Boonekamp, J. J. , Ros, A. H.F. and Verhulst, S. (2008) Immune activation suppresses plasma testosterone level: a meta-analysis. (gla.ac.uk)
  • Many studies have investigated the ICHH by administrating testosterone, and a recent meta-analysis found little evidence that testosterone suppressed immune function. (gla.ac.uk)
  • We present a meta-analysis to test for this effect. (gla.ac.uk)
  • PDF] A meta-analysis of 25 years of mood-creativity research: hedonic tone, activation, or regulatory focus? (semanticscholar.org)
  • This meta-analysis synthesized 102 effect sizes reflecting the relation between specific moods and creativity. (semanticscholar.org)
  • This study was an unbiased statistical meta-analysis of published neuroimaging studies of TS structures. (researchsquare.com)
  • Our present meta-analysis primarily revealed significant increases in grey matter volumes in the thalamus and lentiform nucleus, and decreased grey matter volumes in the anterior cingulate gyrus, of TS patients compared to those in healthy controls. (researchsquare.com)
  • Therefore, in the present study, we performed a meta-analysis on the results of studies reporting grey matter abnormalities in TS patients. (researchsquare.com)
  • The recent development of neutron activation analysis and mass spectrometric methods for the determination of /sup 232/Th in seawater has made possible rapid sampling and analysis of this long-lived, non-radiogenic thorium isotope on small-volume samples. (unt.edu)
  • If the ratio of phosphorus to sulfur or chlorine is small, as it is in most natural waters, accurate analyses by these methods are difficult to achieve. (usgs.gov)
  • Our methodology combines energy methods and exploits the phase-plane geometry of the mathematical model, and we obtain sufficient conditions that support the validity of the standard, reverse and total quasi-steady-state approximations for the intermolecular autocatalytic zymogen activation reaction mechanism. (umich.edu)
  • EC Commission Regulation No 333/2007 of 28 March 2007, Laying down the methods of sampling and analysis for the official control of the levels of lead, cadmium, mercury, inorganic tin, 3-MCPD and benzo(a)pyrene in foodstuffs. (springer.com)
  • The aim of the study was to design and apply pre-processing and analysis methods for cDNA microarray data to explore changes caused by PKC and PKA activation on Jurkat T cell gene expression and the influence of Vpr therein. (uta.fi)
  • Methods: The microarray data analysis included removing missing and saturated intensity values. (uta.fi)
  • This unit describes three methods for the detection of caspase activation as cells undergo apoptosis. (elsevier.com)
  • The observation that the existing snf mutations present a lethal phenotype only in certain genetic backgrounds suggests that snf is required, but is not essential, for the activation of Sex-lethal in the soma. (genetics.org)
  • Mutations that suppressed RetGC activation by GCAP1 produced different effects on the ability of the mutant GUCY2D to bind GCAP1-GFP in HEK 293 cells: some of them suppressed GCAP1 GFP binding while the others had no effect on the binding and evidently caused the loss of GUCY2D activity in vitro through affecting its catalytic activity per se. (arvojournals.org)
  • Our data shows that PIK3CA mutations and PI3K/AKT pathway activation are common events in TNBC. (uniss.it)
  • Our data provide the first transcriptomic analysis of microglia at multiple stages after different SCI severities. (frontiersin.org)
  • Our results support the use of CD154 expression as a practical and reliable method to isolate live Ag-specific CD4 + T cells for transcriptomic analysis and potentially for a range of other studies in infected or previously immunized hosts. (elsevier.com)
  • Classical activation of macrophages induces a wide range of signaling and vesicle trafficking events to produce a more aggressive cellular phenotype. (nih.gov)
  • Bioinformatics analysis based on publicly available binary protein interaction data produced a putative interaction network of MAPs in activated macrophages. (nih.gov)
  • C , densitometric analysis revealed a substantial and significant increase in acetylated tubulin levels in IFN-γ/LPS-treated macrophages compared with control macrophages. (nih.gov)
  • SCI triggers microglia activation, peripheral macrophages and neutrophil infiltration that together govern neuroinflammation after central nervous system (CNS) injury ( David and Kroner, 2011 ). (frontiersin.org)
  • Macrophages are subject to a wide range of cytokine and pathogen signals in vivo, which contribute to differential activation and modulation of inflammation. (biorxiv.org)
  • Though experimental results have shown the transitions between these two types of macrophages, little is known about the dynamic progression of macrophages activation. (biomedcentral.com)
  • The stability analysis provided a possible strategy to intervene the balance of classically and alternatively activated macrophages in this study. (biomedcentral.com)
  • In addition to the elemental and isotopic analysis of samples, INAA permits the analysis of non-radioactive tracers introduced into biological, chemical, and/or industrial processes for process identification and optimization. (ncsu.edu)
  • For example, the effector molecule Raf-1 kinase is activated by Ras, but how this activation occurs is unknown, although a dimerization mechanism through Ras dimers and other protein factors has been proposed ( 3 ). (pnas.org)
  • Despite these intensive efforts to understand the signal-transduction mechanism from Ras to its effector molecules, the means by which these scaffolding proteins, specialized membrane domains, and oligomerization processes are involved, selected, and orchestrated for the activation of the Ras effector molecules have remained unknown. (pnas.org)
  • Surprisingly, in AOX1A, replacement of CysI by alanine, which cannot form a (thio)hemiacetal, led to even higher activities, pointing to an alternative mechanism of activation. (plantphysiol.org)
  • The general intermolecular mechanism for the autocatalytic activation of zymogens is governed by the single-enzyme, single-substrate catalyzed reaction following the Michaelis-Menten mechanism of enzyme action, where the substrate is the zymogen and the product is the same enzyme that is catalyzing the reaction. (umich.edu)
  • In this article we investigate the nonlinear chemical dynamics of the intermolecular autocatalytic zymogen activation reaction mechanism. (umich.edu)
  • The strongest evidence for this mechanism comes from analysis of a bacterial enhancer-like element ( 32 ). (asm.org)
  • In contrast to Bax, Bak is always present on the OMM, but it also undergoes a conformational change and oligomerises during apoptosis, suggesting similarities in the mechanism of activation [ 11 , 12 ]. (pubmedcentralcanada.ca)
  • Mechanism of activation by anions of phosphoglycolate phosphatases from spinach and human red blood cells. (scialert.net)
  • We have investigated 'Extended antigen presentation (EAP)', a new mechanism of naive T cell activation, using two pairs of cognate antigens and antigen-specific T cells, TEa and OT-II. (nii.ac.jp)
  • Until the introduction of ICP-AES and PIXE, NAA was the standard analytical method for performing multi-element analyses with minimum detection limits in the sub-ppm range. (wikipedia.org)
  • By suitable reagent purification, counting for longer times, and activation of larger aliquots, the detection limit could be lowered several hundredfold. (usgs.gov)
  • A method of chemical analysis based on the detection of characteristic radionuclides following a nuclear bombardment. (umassmed.edu)
  • Cellular expression of activation markers (CD38, HLA-DR), memory markers (CD27), and functional intracellular cytokine and proliferation (IFN-γ, Ki-67, TNF-α) markers were measured using multi-color flow cytometry. (whiterose.ac.uk)
  • These mechanisms have been reported that treatment with statins results in lowering intracellular cholesterol concentration, and then increasing a proteolytic activation of sterol responsive element-binding proteins (SREBPs) [ 1 ]. (hindawi.com)
  • Using blue native polyacrylamide gel electrophoresis (BN-PAGE) we show that Bax forms a 200 kDa complex before caspase activation. (pubmedcentralcanada.ca)
  • Analysis of caspase activation during apoptosis. (elsevier.com)
  • When coupled with subcellular fractionation, this method can provide large amounts of temporal and spatial information about caspase activation. (elsevier.com)
  • Activation strain analyses for the oxidative addition of methane to Ni(PH3)2, Pd(PH3)2, and Pt(PH3)2. (nih.gov)
  • These results suggest that continuous activation of the brain renin-angiotensin system impairs cognitive function via stimulation of the angiotensin II type 1 receptor with a decrease in cerebral surface blood flow and an increase in oxidative stress. (ahajournals.org)
  • The genetic analysis of snf: a Drosophila sex determination gene required for activation of Sex-lethal in both the germline and the soma. (genetics.org)
  • In the soma, activation of Sex-lethal appears to be sensitive to snf gene dosage only when the probability of Sex-lethal activation has been otherwise reduced. (genetics.org)
  • In S. cerevisiae , upstream activation sequences (UASs) are generally located within a few hundred base pairs of a target gene, while in Drosophila and mammals, enhancers are often several kilobases away. (asm.org)
  • As the S. cerevisiae genome is compact, and the majority of yeast promoters range from approximately 150 to 400 bp ( 28 , 59 ), it seems logical that there would be restrictions on activation distance in order to maintain specificity between a UAS and its target gene. (asm.org)
  • To elucidate the first steps of sexual fate specification, we profiled the XX and XY gonad transcriptomes at fine granularity during this period and resolved cascades of gene activation and repression. (sigmaaldrich.com)
  • VDR is induced by p53 as well as several other p53 family members, and analysis of chromatin immunoprecipitation showed that p53 protein binds to conserved intronic sequences of the VDR gene in vivo . (aacrjournals.org)
  • Background and aims: Protein kinases C (PKC) and A (PKA) are central signalling molecules in T cell activation and are involved in regulating gene expression. (uta.fi)
  • Exposure of neutrophils to cytokines or chemokines, results in their activation and changes in gene expression profiles. (uu.nl)
  • We examined the possibility that continuous activation of the human brain renin-angiotensin system causes cognitive impairment, using human renin (hRN) and human angiotensinogen (hANG) gene chimeric transgenic (Tg) mice. (ahajournals.org)
  • Analysis of apoptosis in lymph nodes of HIV-infected persons. (jimmunol.org)
  • Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. (jimmunol.org)
  • Furthermore, a significant correlation was observed between intensity of apoptosis and degree of activation of the lymphoid tissue associated with HIV infection. (jimmunol.org)
  • In most cells, apoptosis occurs when mitochondrial outer membrane permeabilisation (MOMP) releases into the cytosol factors, including cytochrome c and SMAC/Diablo, which result in the activation of caspases. (pubmedcentralcanada.ca)
  • 4 - 6 Activation of these downstream effectors up-regulates Mcl-1, Bcl-X L , and survivin, allowing leukemia cells to evade apoptosis. (bloodjournal.org)
  • We and others have recently reported that FLT3 inhibition has been shown to reduce Mcl-1 levels and induce Bax activation, resulting in mitochondrial apoptosis in FLT3/ITD AML cells. (bloodjournal.org)
  • There is evidence that transformed cells are more sensitive to p53-induced apoptosis than their normal counterparts, leading to the suggestion that activation of p53 may cause tumor-specific cell killing. (bloodjournal.org)
  • Complement activation is regulated by a complex group of membrane-bound and fluid-phase proteins ( 1 ). (pnas.org)
  • Factor H is an abundant serum complement regulatory protein that inhibits the alternative pathway of complement activation. (pnas.org)
  • Taken together, our results demonstrate that AOX isoforms are differentially activated and that activation at CysI and CysII is additive. (plantphysiol.org)
  • The question as to whether the biological activities of TSST-1, e.g., lymphocyte extravasation, toxicity and increased sensitivity to LPS, are mediated by T cell activation or activation by MHC II-only, are unresolved and results are contradictory. (mdpi.com)
  • Our results strongly suggest that long-distance activation in S. cerevisiae is normally limited by Sin4 and other factors and that this constraint plays a role in ensuring UAS-core promoter specificity in the compact S. cerevisiae genome. (asm.org)
  • Taken together, these results indicate that the increased intensity of the apoptotic phenomenon in HIV infection is caused by the general state of immune activation, and is independent of the progression of HIV disease and of the levels of viral load. (jimmunol.org)
  • Results Over a 64-month-period, 107 of 8928 patients undergoing haemodialysis on the dialysis unit required an RRS activation (12 events/1000 patients dialysed). (bmj.com)
  • The results support the previous knowledge that DAG/PKC signalling is involved in mediating processes important for T cell activation. (uta.fi)
  • The results demonstrate that tight complementarity of the protein sequences is necessary for NS2B-dependent activation of NS3. (pasteur.fr)
  • The results also determine residues in the ALKV NS2B cofactor essential for protease activation, giving new insights into protease function in flaviviruses. (pasteur.fr)
  • Results show that p53 activation in stroma cells blunts stroma cell-mediated resistance to FLT3 inhibition, in part through down-regulation of CXCL12. (bloodjournal.org)
  • Indeed, several functional magnetic resonance imaging (fMRI) studies have reported significant activation overlap among these regions. (jneurosci.org)
  • To distinguish these possibilities, we first analyzed the lateral occipitotemporal responses to motion, objects, bodies, and body parts with whole-brain group-average analyses and within-subjects functional region of interest (ROI) analyses. (jneurosci.org)
  • We comprehensively use MD simulations, ligand-docking, and virtual screening simulations along with site-directed mutagenesis and electrophysiological analysis at the macroscopic and single channel levels to understanding the functional dynamics of ligand binding-coupled ion flow in P2XRs in atomic detail. (ukaachen.de)
  • The experimental data for receptor activation by agonist combinations were in agreement with the established views of the overlap of binding sites for several pairs of orthosteric (GABA, β -alanine, and piperidine-4-sulfonic acid) and/or allosteric agents (propofol, pentobarbital, and several neuroactive steroids). (aspetjournals.org)
  • Mutational Analysis of the Critical Bases Involved in Activation of the AreR-Regulated σ54-Dependent Promoter in Acinetobacter sp. (asm.org)
  • Different sarcoma subtypes demonstrated distinct oncogenic pathway activation patterns, and reclassified MFH tumors shared oncogenic pathway activation patterns with their predicted subtypes. (harvard.edu)
  • Conclusions/Significance: STS profiling can aid in diagnosis through a predictor tracking distinct tissue differentiation in unclassified tumors, and in therapeutic management via oncogenic pathway activation and chemotherapy response assessment. (harvard.edu)
  • B cell receptor (BCR) binding to antigen induces a signaling cascade that leads to B cell activation and spreading. (aps.org)
  • Overall, the LPS-activation process induces only minor changes in these patterns of associations. (docphin.com)
  • The aim of this study was to validate previously described phenotypic, activation, and cytokine markers of treatment response in a West African cohort. (whiterose.ac.uk)
  • On activation, Ras diffusion was greatly suppressed/immobilized, suggesting the formation of large, activated Ras-signaling complexes. (pnas.org)
  • During activation, BCR form signaling microclusters that later coalesce as the cell contracts. (aps.org)
  • Several genetically encoded fluorescent biosensors for Ras family GTPases have been developed that permit spatiotemporal analysis of the activation of these signaling molecules in living cells. (semanticscholar.org)
  • Hence, insulin signaling bifurcates downstream of PI 3-kinase, one arm leading to actin remodeling and another to Akt activation, both converging to promote GLUT4 translocation. (diabetesjournals.org)
  • Conclusions: The methodology presented can assist in future design and analysis of microarray data. (uta.fi)
  • Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation. (sigmaaldrich.com)
  • Transcriptional activation correlated with the highest increases in MYC binding at promoters. (sigmaaldrich.com)
  • One striking difference between yeast Saccharomyces cerevisiae and metazoans, however, is the distance over which transcriptional activation occurs. (asm.org)
  • Neutron activation analysis (NAA) is the nuclear process used for determining the concentrations of elements in a vast amount of materials. (wikipedia.org)
  • The method is based on neutron activation and therefore requires a source of neutrons. (wikipedia.org)
  • In some cases irradiated samples are subjected to chemical separation to remove interfering species or to concentrate the radioisotope of interest, this technique is known as Radiochemical Neutron Activation Analysis (RNAA). (wikipedia.org)
  • Neutron activation analysis is a sensitive multi-element analytical technique used for both qualitative and quantitative analysis of major, minor, trace and rare elements. (wikipedia.org)
  • Prompt-gamma neutron activation analysis (PGAA) is a very widely applicable technique for determining the presence and amount of many elements simultaneously in samples ranging in size from micrograms to many grams. (wikipedia.org)
  • De Corte, F., Simonits, A.: Recommended nuclear data for use in the k0 standardization of neutron activation analysis. (springer.com)
  • In this study we measured the transfer of a range of elements measured by neutron activation analysis (NAA) and gamma analysis in four Barn owls (Tyto alba) and one Tawny owl (Strix aluco) from archived samples available from the Predatory Bird Monitoring Scheme, http://pbms.ceh.ac.uk. (nerc.ac.uk)
  • Inappropriate activation of complement is normally prevented by complement inhibitors. (biomedcentral.com)
  • Like Akt activation, Rac-GTP loading was largely prevented by inhibitors of PI 3-kinase, suggesting that Akt and Rac are downstream effectors of PI 3-kinase involved in insulin-induced GLUT4 translocation. (diabetesjournals.org)
  • Small molecule inhibitors have been described that disrupt HDM2-p53 binding, which liberate p53 from its inhibitor and enable p53 activation. (bloodjournal.org)
  • The main objectives of the project are to identify the dynamic molecular mechanisms of ligand activation and gating, along with the molecular mechanisms responsible for ion permeation, conductance, and selectivity. (ukaachen.de)
  • Analysis of Ras activation in living cells with GFP-RBD. (semanticscholar.org)
  • Analysis of activation of OVA-specific T cells. (nih.gov)
  • The regulation by the infused T cells impeded the development of fully competent OVA-specific effector/memory Th2 lymphocytes without inhibiting the initial proliferative response of T cells or promoting activation-induced cell death. (nih.gov)
  • Early T cell activation and proliferation was assessed by the counting of OVA-specific T cells, the determination of cell size, the expression of early activation markers such as CD25 and CD69, and the rate of cell division. (nih.gov)
  • Measurement of activation-induced expression of CD154 has been reported to detect live Ag-specific CD4 + T cells, but this approach remains underexplored and, to our knowledge, has not previously been applied in mycobacteria-infected animals. (elsevier.com)
  • p53 activation by Nutlin-3a was not cytotoxic to stromal cells, but reduced CXCL12 mRNA levels and secretion of CXCL12 partially through p53-mediated HIF-1α down-regulation. (bloodjournal.org)
  • These findings provide genetic support for the hypothesis that proteolytic cleavage of the propeptide by BMP-1/TLD proteases plays a critical role in the activation of latent myostatin in vivo and suggest that targeting the activities of these proteases may be an effective therapeutic strategy for enhancing muscle growth in clinical settings of muscle loss and degeneration. (nih.gov)
  • However, there is no clear understanding of the effect of distance on activation in S. cerevisiae in vivo and no knowledge concerning factors that might play a role in controlling this effect. (asm.org)
  • Specifically, activation maps and bipolar voltages were recorded in vivo from 6 pigs at ~5 weeks following infarct creation, as well as 6 control (normal) pigs. (springer.com)
  • Its critical importance as a regulator of C3 activation in vivo is illustrated by the complement profile reported in factor H-deficient individuals, where alternative pathway activation proceeds unhindered, resulting in markedly reduced C3 levels ( 4 ). (pnas.org)
  • The study design was a secondary analysis of controlled experimental studies. (meresearch.org.uk)
  • Overall, there was a strong suppressive effect of experimental immune activation on testosterone levels (r=−0.52), regardless of whether live pathogens or non-pathogenic antigens were used to challenge the immune system. (gla.ac.uk)
  • Data base analysis of protein expression patterns during T-cell ontogeny and activation. (pnas.org)
  • The data suggested that WSSV infection triggers the activation of NEI in shrimp, which throws a light on the pivotal roles of NEI system mediated by hemocytes in shrimp antiviral immunity. (springer.com)
  • Conclusion: Our pilot data show reductions in expression of T cell activation markers were seen with treatment, but this was not associated with fast or slow sputum conversion at 2 months. (whiterose.ac.uk)
  • Additional Possibility of Data Analysis of Enzyme Inhibition and Activation. (scialert.net)
  • Additional possibility of data analysis of enzyme inhibition and activation.1: Equations for calculation of the k a and k i constants of enzyme activation and nontrivial types of enzyme inhibition. (scialert.net)
  • This study was a secondary data analysis from a study on Illness Management and Recovery (IMR) - a curriculum-based approach to schizophrenia self-management. (iupui.edu)
  • These integrations pull data into Google Analytics for deeper analysis. (google.com.hk)
  • For data that has already been collected and processed, advanced filters on views or segmentation in reports can filter out unwanted data for analysis, including automated filters for excluding bot traffic and spam. (google.com.hk)
  • The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. (plos.org)
  • Immunoblotting is described for following the activation of specific caspases. (elsevier.com)
  • A comparative analysis of the AOX isoenzymes AOX1A, AOX1C, and AOX1D from Arabidopsis ( Arabidopsis thaliana ) revealed that cysteine residues, CysI and CysII, are both involved in 2-oxo acid activation, with AOX1A activity being more increased by 2-oxo acids than that of AOX1C and AOX1D. (plantphysiol.org)
  • A comparative genomic analysis of putative p53 binding sequences may thus be a way to identify the downstream mediators of p53 function. (aacrjournals.org)
  • Comparative analysis of GUCY2D activity and its ability to bind GCAP1-GFP in a cell-based assay provides a useful tool for distinguishing between the direct suppression of GUCY2D activity versus that of GCAP1 or RD3 binding. (arvojournals.org)
  • The method of activation analysis not only increases the sensitivity for many trace elements 1 but also eliminates the necessity for running 'blank' analyses on the reagents since small amounts of impurities contained in the reagents will not be measured. (nature.com)
  • Receiver operating curve analysis of these subsets resulted in 80% sensitivity and 70 and 100% specificity, respectively (AUC of 0.82, p = 0.0156 and 0.84, p = 0.0102). (whiterose.ac.uk)
  • Even drug cues presented outside of conscious awareness (i.e., subliminally) produce robust activation within this circuitry, indicating the sensitivity and vulnerability of the brain to potentially problematic reward signals. (jneurosci.org)
  • However, another component of the ICHH, which has received less empirical interest, suggests that there may also be an interaction in the other direction, with immune activation suppressing testosterone levels. (gla.ac.uk)
  • The latter is important because it shows that immune activation per se suppresses testosterone levels. (gla.ac.uk)
  • Thus, a trade-off between immunocompetence and sexual displays may primarily be generated by the effect of immune activation on testosterone, rather than the opposite effect that has received most attention. (gla.ac.uk)
  • The primary aim of this investigation was to evaluate the effect of training on the immune activation in skeletal muscle in response to an acute bout of resistance exercise (RE). (elsevier.com)
  • Here, we present an integrated time-course analysis of transcription and mRNA dynamics following MYC activation in proliferating mouse fibroblasts, based on chromatin immunoprecipitation, metabolic labeling of newly synthesized RNA, extensive sequencing, and mathematical modeling. (sigmaaldrich.com)
  • Pharmacologic activation of the transcription factor NRF2 has been suggested to offer a strategy for cancer prevention. (aacrjournals.org)
  • Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway. (nih.gov)
  • On these grounds, we have exploited an integrated approach based on next generation whole-exome sequencing (WES) and genome-wide high-density single-nucleotide polymorphism (SNP) analysis to investigate the CLL coding genome. (rupress.org)
  • We applied a Fab-based live endogenous modification labeling technique to monitor the changes in histone modification levels during zygotic genome activation (ZGA) in living zebrafish embryos. (biologists.org)
  • We constructed a genome‐scale metabolic network for the RAW 264.7 cell line to determine metabolic modulators of activation. (embopress.org)
  • Direct activation of the GABA A receptor and potentiation of transmitter-activated receptors underlie the clinical actions of GABAergic anesthetics. (aspetjournals.org)
  • Then, at each recording point, activation-recovery intervals ARIs (clinical surrogates of action potential duration) were found by subtracting activation times from repolarization times. (springer.com)
  • False Positive STEMI Activations in a Regional Network: Comprehensive Analysis and Clinical Impact. (revespcardiol.org)
  • We aimed to determine the prevalence, predictors, and clinical impact of false-positive activations within the Catalonian STEMI network ( Codi Infart ). (revespcardiol.org)
  • Code activations were classified as appropriate if they satisfied both electrocardiogram and clinical STEMI criteria. (revespcardiol.org)
  • Appropriate activations were classified as false positives using 2 nonexclusive definitions: a) "angiographic" if a culprit coronary artery was not identified, and b) "clinical" if the discharge diagnosis was other than STEMI. (revespcardiol.org)
  • Frequency distribution analysis of activation times and regional fibrosis in murine Scn5a+/- hearts: the effects of ageing and sex. (surrey.ac.uk)
  • The standard interpretation of this overlap would be that the common areas of activation reflect engagement of common neural systems. (jneurosci.org)
  • However, a plausible alternative account of the overlap between hMT, LO, and EBA (and perhaps also for overlapping activations in other brain areas) is that commonly activated voxels contain independent neural systems, each coding for a stimulus or task dimension but intermixed at a resolution below that of individual fMRI voxels. (jneurosci.org)
  • 2006). Analysis of the local patterns of neural activity on a voxelwise basis can detect small but stable variations in selectivity. (jneurosci.org)
  • We analyzed several independent microarray datasets, to identify a predictor, use it to classify unclassifiable sarcomas, and assess oncogenic pathway activation and chemotherapy response. (harvard.edu)
  • Bayesian models of oncogenic pathway activation and chemotherapy response were applied to individual STS samples. (harvard.edu)
  • A single-molecule fluorescence resonance energy transfer (FRET) method has been developed to observe the activation of the small G protein Ras at the level of individual molecules. (pnas.org)
  • Through analysis of the N-terminome by iTRAQ-TAILS, we identified cotranslational and posttranslational αN-acetylation motifs, quantitative increases in protein abundance, and qualitative changes in the proteolytic signature during inflammation. (sciencemag.org)
  • It is often inferred that Bax activation occurs in a single step, a conformational change in the protein bringing about its translocation and oligomerisation into high molecular weight membrane pores. (pubmedcentralcanada.ca)
  • The latter triggers activation of several serine/threonine kinases, notably Akt, which, through its substrate AS160, regulates GLUT4 vesicle mobilization to and/or fusion with the plasma membrane ( 2 ). (diabetesjournals.org)
  • Our study demonstrates metabolism's role in regulating activation may be greater than previously anticipated and elucidates underlying connections between activation and metabolic effectors. (embopress.org)
  • Analysis of interaction with synthesis and degradation in linear ubiquitin mediated NF-kappaB activation. (nii.ac.jp)
  • In contrast, multi-voxel analyses of variations in selectivity patterns revealed that visual motion, object form, and the form of the human body elicited three relatively independent patterns of fMRI activity in lateral occipitotemporal cortex. (jneurosci.org)
  • Regarding Raf activation, the further involvement of Raf-scaffolding proteins, such as KSR and 14-3-3, has been suspected ( 11 , 12 ). (pnas.org)
  • Overall the analysis identified 409 proteins that bound directly or indirectly to MTs. (nih.gov)
  • We describe a detailed immunohistochemical study to localise a strategically selected set of complement proteins, activation products and regulators in brain and spinal cord tissue of 17 patients with progressive multiple sclerosis and 16 control donors, including 9 with central nervous system disease. (biomedcentral.com)
  • B , Western blot analysis of total cell lysates. (nih.gov)
  • This observation is in agreement with the notion that DCs prevent the premature destruction of antigenic determinants to optimize T cell activation. (rupress.org)
  • These peptides are produced mainly from antigens that have been internalized and processed in the endocytic pathway of APCs, where they meet class II molecules en route to the cell surface ( 1 , 2 ). (rupress.org)
  • The macrophage cell line J774 is a well-characterized model for analysis of phagosome biogenesis ( 13 , 14 ). (rupress.org)
  • Analysis of T-cell activation after bronchial allergen challenge in patients with atopic asthma. (harvard.edu)
  • C) Analysis of cell division of OVA-specific CD4+ lymphocytes. (nih.gov)
  • Hope (goal-directed thinking) and patient activation (knowledge and skills to manage one's illness) are both important in managing chronic conditions like schizophrenia. (iupui.edu)
  • Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of mammalian sex determination. (sigmaaldrich.com)