Activation analysis in which the specimen is bombarded with neutrons. Identification is made by measuring the resulting radioisotopes. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A method of chemical analysis based on the detection of characteristic radionuclides following a nuclear bombardment. It is also known as radioactivity analysis. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Determination of the energy distribution of gamma rays emitted by nuclei. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.
A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Stable zinc atoms that have the same atomic number as the element zinc, but differ in atomic weight. Zn-66-68, and 70 are stable zinc isotopes.
A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002,1985), chromium and some of its compounds have been listed as known carcinogens.
An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.
A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.
The relative amounts of various components in the body, such as percentage of body fat.
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.

A bone calcium index based on partial-body calcium measurements by in vivo activation analysis. (1/35)

Measurements of partial-body calcium by in vivo neutron activation analysis have been carried out on normal and osteoporotic subjects. Based on measurements on 16 normal subjects (volunteers less than 55 years of age), a calcium index has been established that takes into account variation in skeletal frame size. On the basis of this index, all osteoporotic patients have bone mineral content less than any of the normal subjects. The normal calcium indices range from 0.9 to 1.2, and the osteoporotic indices ranged from 0.41 to 0.83. Thirteen of 22 volunteers over 55 years of age had calcium indices less than 0.9 in agreement with the expected loss of calcium with age. Measurements of total-body potassium were also made on these same subjects and the calcium/potassium ratios calculated. Although as groups the older volunteers and older osteoporotic subjects had mean calcium/potassium ratios similar to the mean for the normal subjects, the osteoporotic subjects under 55 years of age had a mean calcium/potassium ratio significantly lower, indicationg that for this latter group the loss in bone mineral was not associated with a corresponding loss in muscle mass.  (+info)

Phonton absorptiometry and skeletal mass in the treatment of osteoporosis. (2/35)

Thirty-six osteoporotic patients who underwent several therapeutic regimes were studied on two occasions by photon absorptiometry and total-body neutron activation analysis (TBNAA). These determinations were made at a mean interval of 8.9 plus or minus 0.8 months. The 8-cm radial site was chosen for the photon absorptiometry which was performed with the Norland-Instruments Densitometer. Mean initial bone mineral content (BMC) was 0.724 plus or minus 0.069 gm/cm and mean bone width was 1.235 plus or minus 0.072 cm. The mean percent change in BMC (%deltaBMC) was 1.02 plus or minus 4.2. The initial total-body calcium (TBCa) as determined by TBNAA was reduced when compared with values that would be expected from empirically derived formulas. The mean percent change in TB-Ca (%deltaTB-Ca) was -3.2 plus or minus 4.7. Most patients displayed a change in BMC and TB-Ca that was at least 2 s.d. greater than the precision of the methods used (%deltaTB-Ca greater than 2). No relationship was found between the deltaBMC and the deltaTB-Ca (r = 0.17). These findings suggest that changes in the radical BMC at the 8-cm site cannot be extrapolated to indicate changes in skeletal mass in response to treatment of osteoporosis. Whether photon absorptiometry at other sites or at multiple sites provides a closer relationship to changes in skeletal mass (TB-Ba) remains to be determined.  (+info)

Preliminary observations on excretion of 37Ar from man following whole-body neutron activation--an indicator of total-body calcium. (3/35)

Measurements of exhaled 37-Ar produced by total-body neutron irradiation of 40-Ca were used to determine total-body calcium in 16 human subjects. There was a good correlation between body calcium using the 30-min postirradiation breath sample of 37-Ar and body calcium determined by measurement of 49-Ca.  (+info)

Effects of activation sequence on the local recovery of ventricular excitability in the dog. (4/35)

We measured refractory periods at ventricular sites in the dog heart during drive from ventricular test sites and during combined drive from the test sites and other ventricular sites or the atrium. We found that ventricular activation sequence caused significant alterations on refractory period. Combined drive from two sites which resulted in fusion complexes was associated with shorter refractory periods at the test sites than those observed during drive at the test sites only. Our findings are explicable because earlier excitation and consequent earlier recovery of surrounding areas during fusion beats exerts an electrotonic influence on test sites.  (+info)

Length-induced changes in activation during contraction. A study of mechanical oscillations in strontium-mediated contractions of cat and frog heart muscle. (5/35)

The plateau phase of prolonged Sr-mediated contractions of preparations of cat and frog heart muscle was used to study the transient response to abrupt changes in load or length. An oscillatory response (total amplitude equal to or less than 5% Lmax) was obtained. Isotonic oscillations were less damped than their isometric counterparts, implying positive feedback and thus a causal role of the perturbation in length. Oscillation frequency was 2-3 HZ at 29 degrees C (Q 10, 2-3); it could be increased by epinephrine or caffeine, independently of their effects on extent of shortening; it otherwise changed as a generally constant function of the length at which the oscillation occurred, whether this was altered by changes in extracellular [Sr], frequency of contraction, or load (independent of the direction and magnitude of the preceding load step). Similar oscillatory responses were induced during Sr- or Ca-mediated contractures. Cat muscles showed an additional slower component to the oscillatory response. Transient augmentation of the velocity-length relationship after abrupt reduction in load, previously described for twitch contractions under certain conditions, appears to be analogous to the first phase of the oscillatory response studied here. Our findings indicate that the oscillation is not attributable to any mechanism intrinsic to myofilament interaction, but rather that it involves length-induced changes in the level of activation, probably mediated by Ca2+ or Sr2+. We conclude that length influences the level of activation during contraction of heart muscle.  (+info)

MICROSCOPIC DETERMINATION OF BONE PHOSPHORUS BY QUANTITATIVE AUTORADIOGRAPHY OF NEUTRON-ACTIVATED SECTIONS. (6/35)

Longitudinal sections of human cortical bone were submitted to thermal neutrons. gamma-ray spectra were recorded repeatedly during 15 days following irradiation. They showed that Na(24) is predominant as early as 3 hours after activation and that all the gamma-emitters have decayed on the 15th day. When the gamma-rays have disappeared, beta-rays are still produced by the sections. It was proved by the absorption curve in aluminium that all these beta-rays are issued from the P(32) induced in the sections by activation of P(31). Therefore autoradiograms registered 15 days after activation reveal the distribution of P(32) in the sections. gamma-ray spectra and beta-ray absorption curves of neutron activated sections of ivory demonstrated a mineral composition similar to that of bone. Autoradiograms of ivory sections activated for various times were used to establish the relation between the optical density of the autoradiograms and the radioactivity in P(32). When the bone autoradiograms are compared with the ivory standards of known radioactivity, the optical densities of single osteons (Haversian systems), can be related to their phosphorus contents. Autoradiograms and microradiograms of the same sections were examined side by side. The least calcified osteons, that contain 80 per cent of the calcium of the fully calcified osteons, also contain about 80 per cent of the phosphorus of the fully mineralized osteons. It is concluded that the Ca:P ratio remains constant while mineralization of bone tissue is being completed.  (+info)

Heparin-stimulated inhibition of factor IXa generation and factor IXa neutralization in plasma. (7/35)

Generation and inhibition of activated factor IXa was studied in factor XIa-activated plasma containing 4 mmol/L free calcium ions and 20 mumol/L phospholipid (25 mol% phosphatidylserine/75 mol% phosphatidylcholine). Interference of other (activated) clotting factors with the factor IXa activity measurements could be avoided by using a highly specific and sensitive bioassay. Factor IXa generation curves were analyzed according to a model that assumed Michaelis-Menten kinetics of factor XIa-catalyzed factor IXa formation and pseudo first order kinetics of inhibition of factor XIa and factor IXa. In the absence of heparin, factor IXa activity in plasma reached final levels that were found to increase with increasing amounts of factor XIa used to activate the plasma. When the model was fitted to this set of factor IXa generation curves, the analysis yielded a rate constant of inhibition of factor XIa of 0.7 +/- 0.1 min-1 and a kcat/Km ratio of 0.29 +/- 0.01 (nmol/L)-1 min-1. No neutralization of factor IXa activity was observed (the estimated rate constant of inhibition of factor IXa was 0). Thus, in the absence of heparin, the final level of factor IXa in plasma is only dependent on the initial factor XIa concentration. While neutralization of in situ generated factor IXa in normal plasma was negligible, unfractionated heparin dramatically enhanced the rate of inactivation of factor IXa (apparent second order rate constant of inhibition of 5.2 min-1/per microgram heparin/mL). The synthetic pentasaccharide heparin, the smallest heparin chain capable of binding antithrombin III, stimulated the inhibition of in situ generated factor IXa, but sevenfold less than unfractionated heparin (k = 0.76 min-1 per microgram pentasaccharide/mL). We found that free calcium ions were absolutely required to observe an unfractionated heparin and pentasaccharide-stimulated neutralization of factor IXa activity. Factor XIa inhibition (psuedo first order rate constant of 0.7 min-1) was not affected by unfractionated heparin or pentasaccharide in the range of heparin concentrations studied.  (+info)

Post-separation detection of nucleic acids and proteins by neutron activation. (8/35)

We describe approaches to neutron activation analysis and their application to post-separation autoradiographic detection of biological compounds. Specifically, we have extended the use of a "direct-labeling" method to the post-separation detection of DNA after gel electrophoresis and to the detection of nucleotides separated by TLC. In addition, we describe a more generally applicable "indirect-labeling" method in which separated compounds of interest are selectively bound to ligands containing highly neutron-activatable elements, such as manganese (55Mn), europium (151Eu), or dysprosium (164Dy), and then irradiated with thermal neutrons. This method is illustrated with nucleotides separated by TLC and with proteins separated by polyacrylamide gel electrophoresis. In contrast to the direct-labeling approach, the indirect-labeling method can be adapted to detect any class of substances for which a highly neutron-activatable, selectively binding ligand is available. The theoretically achievable sensitivity of the indirect-labeling method is in the attomole (10(-18) mol) range.  (+info)

... is used to measure bromide so that extraction is not necessary for analysis. NAA is used in geology ... this technique is known as Radiochemical Neutron Activation Analysis (RNAA). NAA can perform non-destructive analyses on solids ... Neutron activation analysis (NAA) is the nuclear process used for determining the concentrations of elements in many materials ... Neutron activation analysis is also used to create standards in the semiconductor industry. Semiconductors require a high level ...
Prompt-gamma neutron activation analysis (PGAA) is a very widely applicable technique for determining the presence and amount ... This article incorporates public domain material from Prompt-Gamma Activation Analysis (PGAA) Spectrometer. National Institute ... Harder, J. 2009, 'Material analysis for process control in cement plants', ZKG INTERNATIONAL, 6/7 - 2009, Volume 62, p. 64 ...
In this sense, neutron activation is a non-destructive analysis method. Neutron activation analysis can be done in situ. For ... Neutron activation analysis is one of the most sensitive and precise methods of trace element analysis. It requires no sample ... Neutron Activation Analysis web Handbook on Nuclear Activation Cross-Sections, IAEA, 1974 Decay Data in MIRD Format from the ... An example of 55Fe production from iron rebar activation is shown below: 54 26Fe + 1 0n → 55 26Fe Neutron activation is the ...
... (AEA), also known as large activation energy asymptotics, is an asymptotic analysis used in the ... This condition forms the basis for activation energy asymptotics. Denoting T u {\displaystyle T_{\rm {u}}} for unburnt gas ... Bush, W. B., & Fendell, F. E. (1970). Asymptotic analysis of laminar flame propagation for general Lewis numbers. Combustion ... Liñán, A. (1971). A theoretical analysis of premixed flame propagation with an isothermal chain reaction. AFOSR Contract No. ...
... with this LAG3 contributing to APC activation. In August 2002 the first phenotypic analysis of the murine LAG-3 was reported by ... "Biochemical analysis of the regulatory T cell protein lymphocyte activation gene-3 (LAG-3; CD223)". Journal of Immunology. 173 ... "Molecular cloning and expression analysis of pig lymphocyte activation gene-3 (LAG-3; CD223)". Veterinary Immunology and ... molecular analysis of the negative regulatory function of lymphocyte activation gene-3". Journal of Immunology. 169 (10): 5392- ...
Wang B, Mu Y, Ni F, Zhou S, Wang J, Cao Y, Ma X (April 2010). "Analysis of FOXO3 mutation in 114 Chinese women with premature ... The pathway is therefore implicated in the activation of ovarian primordial follicles. In in vitro activation of ovarian ... Ovarian follicle activation can be defined as primordial follicles in the ovary moving from a quiescent (inactive) to a growing ... In vitro activation (IVA) consists of the combination of disrupting the hippo signalling pathway and stimulation of Akt ...
"Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha". The Journal of ... in silico analysis of an mRNA expression database for fibroblast activation protein and endosialin". Cancer Immunity. 5: 10. ... "Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha". The Journal of ... Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that in humans is encoded ...
PAM was developed using qualitative methods, Rasch analysis, and classical test theory psychometric methods. Developed by ... "Measuring patient activation in the Netherlands: translation and validation of the American short form Patient Activation ... "Development of the Patient Activation Measure (PAM): Conceptualizing and measuring activation in patients and consumers". ... The Patient Activation Measure is being used in a number of ways to improve the delivery of health care, including: a metric to ...
"Neutron-Activation Analysis". Karws.gso.uri.edu. Archived from the original on May 20, 2010. Retrieved August 3, 2010. Rahn, K ... see section on neutron activation analysis). This "single bullet," which was full metal jacketed and specifically designed to ... According to the analysis done by the HSCA, the horizontal angle from the 6th floor window of the Texas School Book Depository ... D. M. Green, "Analysis of Earwitness Reports Relating to the Assassination of President John F. Kennedy", Report No. 4034, 8 ...
Activation analysis is one of the most sensitive and versatile techniques possible for elemental analysis. The technique ... Activation Analysis". In Alfassi, Zeev B. (ed.). Instrumental Multi-element Chemical Analysis. Dordrecht: Kluwer. p. 93. ... In a second type, Neutron activation analysis (NAA), a stream of neutrons generated in a particle accelerator is directed onto ... "activation analysis." The general method exploits two natural phenomena: the tendency to form stable atoms with a given energy ...
... or neutron activation analysis. Inductively coupled plasma atomic emission spectroscopy (ICP-AES) is used for zinc ... of zinc in urine samples requires extraction of the metals with a polydithiocarbamate resin prior to digestion and analysis ( ...
Because they outnumber by far the leucocytes they need to be removed to do a FACS analysis of the basophils. Innate immune ... Pilot study on basophil activation induced by contrast medium. Fundam Clin Pharmacol 2011;25:267 - 276 Janeway CA, Jr.; et al ... but the activation of basophilic granulocytes with anti-IgE, the expression of the CD63 antigen on the cell surface (plasma ...
Display of activation foci. Generation of flat, inflated, spherical surfaces. Mapping of fMRI volumes onto surfaces. Surface ... Image of CARET main window with functional and foci data on surface Analysis of group anatomical differences using sulcal depth ... CARET (Computerized Anatomical Reconstruction Toolkit) is a software application for the structural and functional analysis of ...
and SOMO-activation by organocatalysts Despite their shortcomings, these techniques may serve as excellent calibration methods ... Reaction progress kinetic analysis relies on the ability to accurately monitor the reaction conversion over time. This goal may ... Unlike more common pseudo-first-order analysis, in which an overwhelming excess of one or more reagents is used relative to a ... It is important to note that even while kinetic analysis is a powerful tool for determining the stoichiometry of the turn-over ...
Neutron activation analysis can be used to remotely detect the chemical composition of materials. This is because different ... Prompt Gamma-ray Neutron Activation Analysis. International Atomic Energy Agency D. Franklin; R. B. Adamson (1 January 1984). ...
WGA dubbed Windows Activation Technologies with Windows 7 "Ubuntu Linux Validates As Genuine Windows". Slashdot. 2007-06-18. ... Analysis, Comments and Product Reviews for IT Professionals The Ed Bott Report , Page 221 , ZDNet Dvorak, John C. (October 16, ... In Windows 7, WGA is renamed Windows Activation Technologies. Despite its name it does not actually evaluate the integrity or ... Office Genuine Advantage Windows Product Activation Digital rights management "The Windows Genuine Advantage (WGA) validation ...
Pulsed Fast Thermal Neutron Activation), the prompt gamma neutron activation analysis (PGNAA) and Laser-induced breakdown ... "Prompt gamma neutron activation analysis (PGNAA)." The Cement Plant Operations Handbook. Fifth ed. October 2007. Berg, Joel L ... The technology most frequently found in bulk material analysis and coal analysis are PFTNA ( ... Capitalizing on the unique gamma ray spectrum associated with each element, the instrument can perform an analysis each minute ...
Further analysis has shown that TAR is a pre-microRNA that produces mature microRNAs from both strands of the TAR stem-loop. ... The HIV trans-activation response (TAR) element is an RNA element which is known to be required for the trans-activation of the ... Page for Trans-activation response element (TAR) at Rfam miRBase page for hiv1-mir-TAR v t e (GO template errors, MicroRNA, Cis ... Krachmarov, Chavdar P.; Chepenik, Lara G.; Barr-Vagell, Sharon; Khalili, Kamel; Johnson, Edward M. (1996). "Activation of the ...
"Behavioural activation for depression; an update of meta-analysis of effectiveness and sub group analysis". PLOS ONE. 9 (6): ... Behavioral activation emerged from a component analysis of cognitive behavioral therapy. This analysis found that any cognitive ... Behavioral activation comes under the heading clinical behavior analysis or what is often termed third generation behavior ... A meta-analysis study comprising 34 Randomized Controlled Trials found that while Behavioral Activation treatment of adults ...
February 2014). "Transcriptome-based network analysis reveals a spectrum model of human macrophage activation". Immunity. 40 (2 ... M1-activation in vitro is evoked by treatment with TLR ligands such as bacterial lipopolysaccharide (LPS) - typical for Gram- ... The M2b macrophages produce IL-1, IL-6, IL-10, TNF-𝛼 as a response to immune complexes or LPS, leading to activation of Th2 ... Macrophage activation spectrum is thus considered to be wider, involving complex regulatory pathway to response to plethora of ...
Modern Genetic Analysis - via NCBI. Busby, Steve; Ebright, Richard H (1999-10-22). "Transcription activation by catabolite ... Activation domains also come in a variety of types that are categorized based on the domain's amino acid sequence, including ... The breakdown of maltose in Escherichia coli is controlled by gene activation. The genes that code for the enzymes responsible ... "activation domain". Most activators function by binding sequence-specifically to a regulatory DNA site located near a promoter ...
After activation, LysRS is phosphorylated on Serine 207 in a MAPK-dependent manner. This phosphorylation causes LysRS to change ... Although hUBC9 is known to act preferentially with SENTRIN/SUMO1, an in vitro analysis demonstrated greater actual association ... Activation of the LysRS-Ap4A-MITF signalling pathway by isoproterenol has been confirmed in cardiomyocytes. A heart specific ... Activation of this cis-regulatory sequences by DDX3X promotes MITF expression in melanoma cells. Microphthalmia Splashed white ...
Friston, K.; Poline, J-P.; Holmes, C.J.; Frith, C.D.; Frackowiak, R.S. (1996). "A multivariate Analysis of PET activation ... based on Principal Component Analysis or Independent Component Analysis decomposition. Polynomial kernel SVM has been shown to ... Manual analysis of these images can be time-consuming and unreliable. CAD has been employed to enhance the accuracy, ... Zhang, J.; Yu, C.; Jiang, G.; Liu, W.; Tong, L. (2012). "3d texture analysis on mri images of alzheimer's disease". Brain ...
In 1936, he invented Neutron Activation Analysis. In 1943 he fled to Stockholm (Sweden being neutral during the war), where he ...
Meinke, W. W.; Anderson, R. E. (1954). "Activation Analysis of Several Rare Earth Elements". Analytical Chemistry. 26 (5): 907- ... A larger amount of 154Eu is produced by neutron activation of a significant portion of the non-radioactive 153Eu; however, much ...
Activation kinetics are unaffected by RNA editing. Changes in inactivation kinetics affect the duration and frequency of the ... 2007). "Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymia". Neurogenetics. 8 (2): 131-5 ... 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... This was determined by electrophysiology analysis. The length of time the membrane is depolarised is decreased, which also ...
Performs security monitoring, security and data/logs analysis, and forensic analysis, to detect security incidents, and mount ... A multi-domain role activation model (PDF). ICC 2017 2017 IEEE International Conference on Communications. IEEE Press. pp. 1-6 ... "Analysis , The Cybersecurity 202: Agencies struggling with basic cybersecurity despite Trump's pledge to prioritize it". The ... A.C. O'Connor & R.J. Loomis (March 2002). Economic Analysis of Role-Based Access Control (PDF). Research Triangle Institute. p ...
Fernandez, I.; Bickelhaupt, F. M. (2012). "Alder-ene reaction: Aromaticity and activation-strain analysis". Journal of ... By computationally examining both the activation barriers and the activation strains of several different ene reactions ... This translates into a lowering of the activation barrier until 61,5 kJ/mol (M06-2X/def2-TZVPP), if S replaces O on the ... MINDO/3 calculations of activation parameters and primary kinetic isotope effects". Journal of the American Chemical Society. ...
Fazio, R. H., Sanbonmatsu, D. M., Powell, M. C., & Kardes, F. R. (1986). On the automatic activation of attitudes. Journal of ... Data re-analysis and commentary on Bargh, Chaiken, Govender, and Pratto (1992). Journal of Personality and Social Psychology, ... Fazio, R. H., Sanbonmatsu, D. M., Powell, M. C., & Kardes, F. R. (1986). On the automatic activation of attitudes. Journal of ... Fazio, R; Jackson, J.R.; Dunton, B.C.; Williams, C.J. (1995). "Variability in automatic activation as an unobtrusive measure of ...
After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and ... Available sequence data analyses indicate splice variants that encode different isoforms. Carboxypeptidase B GRCh38: Ensembl ... Mosnier LO, Meijers JC, Bouma BN (2002). "The role of protein S in the activation of thrombin activatable fibrinolysis ... 1997). "The gene for human carboxypeptidase U (CPU)--a proposed novel regulator of plasminogen activation--maps to 13q14.11". ...
Transition state analyses have used isotopic effects and quantum calculations to reveal a completely dissociated dianionic ... Zhang Y, Deng H, Schramm VL (Dec 2010). "Leaving group activation and pyrophosphate ionic state at the catalytic site of ... Nonetheless, crystallographic analyses and the lack of S. cerevisiae enzyme affinity to substrate analogues where the ... The first one is the substrate carboxyl activation through electrostatic stress. The phosphoryl group binding entails ...
Xiao G, Tsai AL, Palmer G, Boyar WC, Marshall PJ, Kulmacz RJ (February 1997). "Analysis of hydroperoxide-induced tyrosyl ... Minghetti L, Pocchiari M (2007). "Cyclooxygenase‐2, Prostaglandin E2, and Microglial Activation in Prion Diseases". ... Cyclooxygenase-2, prostaglandin E2, and microglial activation in prion diseases. Int. Rev. Neurobiol. International Review of ...
Apt D, Liu Y, Bernard HU (1994). "Cloning and functional analysis of spliced isoforms of human nuclear factor I-X: interference ... "DNA binding and transcriptional activation by the Ski oncoprotein mediated by interaction with NFI". Nucleic Acids Res. 25 (19 ... "DNA binding and transcriptional activation by the Ski oncoprotein mediated by interaction with NFI". Nucleic Acids Res. 25 (19 ... with transcriptional activation by NFI/CTF in a cell-type specific manner". Nucleic Acids Res. 22 (19): 3825-3833. doi:10.1093/ ...
The activation of the c-Src pathway has been observed in about 50% of tumors from colon, liver, lung, breast and the pancreas. ... An immunohistochemical and biochemical analysis". J. Pathol. 180 (4): 383-8. doi:10.1002/(SICI)1096-9896(199612)180:4. 3.0.CO;2 ... The activation of c-Src causes the dephosphorylation of the tyrosine 527. This induces long-range allostery via protein domain ... Since the activation of c-Src leads to the promotion of survival, angiogenesis, proliferation and invasion pathways, the ...
No color after installing S&T 2013 "Review: Microsoft Streets and Trips 2014 - Laptop GPS World". Product activation FAQ and ... In 2000, Microsoft also developed Microsoft MapPoint as a business mapping program for geographic analysis, based on this ... Since version 2008, Microsoft started requiring Product Activation for the retail versions of Streets & Trips, although Volume ... License (VL) versions available through MSDN did not require activation. Microsoft announced the discontinuation of Streets & ...
... after performing analysis on ImageNet data, researchers from Google indicated that using the function as an activation function ... This function uses non-monotonicity, and may have influenced the proposal of other activation functions with this property such ... Ramachandran, Prajit; Zoph, Barret; Le, Quoc V. (2017-10-27). "Searching for Activation Functions". arXiv:1710.05941v2 [cs.NE ... Serengil, Sefik Ilkin (2018-08-21). "Swish as Neural Networks Activation Function". Machine Learning, Math. Archived from the ...
Caspase-3 activation is a cell requirement during early stages of the skeletal myoblast differentiation. Its catalytic site ... "Structure and mutation analysis of the gene encoding DNA fragmentation factor 40 (caspase-activated nuclease), a candidate ... Liu X, Zou H, Widlak P, Garrard W, Wang X (May 1999). "Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase ... Caspase signals resulting from the activation of nuclease CAD indicate that the cell differentiation is due to a CAD ...
A latent variable analysis". Cognitive Psychology. 41 (1): 49-100. CiteSeerX 10.1.1.485.1953. doi:10.1006/cogp.1999.0734. PMID ... behavioral activation, cognitive therapy, interpersonal psychotherapy), flexibility is such an integral part of psychological ...
Factor analysis was also brought into play by both psychologists and sociologists of religion, to establish a fixed core of ... Three main pathways to explain this trend have been offered: placebo effect, focus and attitude adjustment, and activation of ... Gary Leak's Faith Development Scale, or FDS, has been subject to factor analysis by Leak. Other theorists in developmental ... Leak, Gary K (2002). "Exploratory factor analysis of the religious maturity scale". BNET UK. CBS Interactive Inc. Retrieved 22 ...
These sensors can be employed for the analysis of organic and inorganic analytes in various matrices. The determination of ... activation overpotential (defined as η = E − E e q {\displaystyle {\displaystyle \eta =E-E_{\rm {eq}}}} ). At high ... ISBN 978-0-444-51958-0. Harris, Daniel C. (2016-01-01). Quantitative Chemical Analysis, Ninth Edition (9 ed.). W.H. Freeman and ... Skoog, Douglas A. (2018). Principles of instrumental analysis. F. James Holler, Stanley R. Crouch (7th ed.). Australia. ISBN ...
Himmelreich R, Hilbert H, Plagens H, Pirkl E, Li BC, Herrmann R (November 1996). "Complete sequence analysis of the genome of ... their activation into reactive forms using energy from ATP, and thirdly, the assembly of these precursors into complex ... These models are now used in network analysis, to classify human diseases into groups that share common proteins or metabolites ... ISBN 978-0-7167-4339-2. Kelleher JK, Bryan BM, Mallet RT, Holleran AL, Murphy AN, Fiskum G (September 1987). "Analysis of ...
"Shopper Innovation + Activation Awards". Shopper Innovation + Activation Awards. Retrieved May 21, 2020. "Marketing Awards 2020 ... naming Canada's Most Active Community Analysis of the state of physical activity among children & youth, adults and how this ...
January 2003). "Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis". Human ... Donlon TA, Krensky AM, Clayberger C (1990). "Localization of the human T lymphocyte activation gene 519 (D2S69E) to chromosome ... a human late T cell activation molecule with homology to small, lytic, granule proteins". Journal of Immunology. 158 (6): 2680- ... a human NK and T cell-specific activation gene". Immunogenetics. 37 (2): 102-107. doi:10.1007/BF00216832. PMID 8423048. S2CID ...
Gridley T, Gray DA, Orr-Weaver T, Soriano P, Barton DE, Francke U, Jaenisch R (May 1990). "Molecular analysis of the Mov 34 ... This activity is usually attributed to the role of proteasomes in the activation of NF-κB which further regulates the ... "HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation". The Journal of Biological Chemistry. 272 ( ...
... increases cyclic GMP levels in the brain and liver by activation of guanylate cyclase. Sodium azide solutions ... A Literature Review and Analysis". International Journal of Toxicology. 22 (3): 175-186. doi:10.1080/10915810305109. ISSN 1091- ...
1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807-28. doi:10.1101/gr.6.9.807. ... 2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 ( ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National ... "ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells". European ... analysis by computational, comparative, and microarray approaches". Genomics. 78 (3): 155-68. doi:10.1006/geno.2001.6655. PMID ... suggesting the proliferative defect is due either to ICOS-mediated IL-2 secretion or the activation of similar signaling ...
2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF- ... "Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of ...
... carbohydrate recognition and analysis of the b-prims fold". Protein Science. 8 (1): 13-24. doi:10.1110/ps.8.1.13. PMC 2144112. ... "Tyrosine 151 is part of the substrate activation binding site of bovine trypsin: identification by covalent labelling with p- ...
STAT activation initiates the most well-defined cell signaling pathway for all IFNs, the classical Janus kinase-STAT (JAK-STAT ... The analyses showed the reality of interferon activity by chemical verification. The purification of human alpha interferon was ... Minks MA, West DK, Benvin S, Baglioni C (October 1979). "Structural requirements of double-stranded RNA for the activation of 2 ... Knight E, Hunkapiller MW, Korant BD, Hardy RW, Hood LE (February 1980). "Human fibroblast interferon: amino acid analysis and ...
A clinical analysis of 17 cases". Cancer. 37 (3): 1571-1576. doi:10.1002/1097-0142(197603)37:3. 3.0.co;2-l. PMID 1260676. ... 2009). "Activation of sonic hedgehog signaling pathway in olfactory neuroblastoma". Oncology. 77 (3-4): 231-243. doi:10.1159/ ... December 2018). "Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma". Nature ... Dulguerov P, Allal AS, Calcaterra TC (November 2001). "Esthesioneuroblastoma: a meta-analysis and review". The Lancet. Oncology ...
Being infected with HIV increases the rate of activation of latent TB infections, and having TB, increases the rate of HIV ... Moss, Jennifer (2020-10-01). "Persistent Poverty and Cancer Mortality Rates: An Analysis of County-Level Poverty Designations ... Bentwich Z, Kalinkovich A, Weisman Z (April 1995). "Immune activation is a dominant factor in the pathogenesis of African AIDS ... At the same time, chronic worm infections can cause immune activation that increases susceptibility of HIV infection and ...
In Escherichia coli, replication proceeds unidirectionally from oriV after activation by TrfA. In E. coli, multiple plasmid ... Compilation and Comparative Analysis", Journal of Molecular Biology, Volume 239, Issue 5, 23 June 1994, Pages 623-663 Sequence ... sequence analysis and segregational stability.", Plasmid, 2005 Jul;54(1):86-91. Malgorzata Adamczyk and Grazyna Jagura-Burdzy ... comparative genome analysis and an improved genome-scale reconstruction of E. coli", BMC Genomics, 2011, http://www. ...
The usage of a route perspective has no influence on the survey perspective in the activation of the brain, and vice versa. A ... Nazareth, Alina; Huang, Xing; Voyer, Daniel; Newcombe, Nora (2019-10-01). "A meta-analysis of sex differences in human ... Egocentric navigation causes high levels of activation in the right parietal lobe and prefrontal regions of the brain that are ... A Meta-Analysis". Child Development. 56 (6): 1479-1498. doi:10.2307/1130467. ISSN 0009-3920. JSTOR 1130467. PMID 4075870. ...
Methods and Data Analysis for Cross-Cultural Research. Thousand Oaks, CA: Sage, 1997 Cherry, Kendra. "What is Cross Cultural ... Hong, Y. Y.; Chiu, C. Y.; Kung, T. M. (1997). "Bringing culture out in front: Effects of cultural meaning system activation on ... a failure of analysis". Human Relations. 55 (1): 89-118. doi:10.1177/0018726702551004. S2CID 145781752. Kim, U., Triandis, H. C ...
2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ...
These processes are influenced by microvesicles derived from platelets, which can contribute to the activation of fibroblast- ... Analysis of fibroblast-like synoviocytes". Arthritis Research & Therapy. 6 (2): R161-8. doi:10.1186/ar1153. PMC 400437. PMID ...
Zheng XF, Ruderman JV (1993). "Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25". ... 1991). "Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein". Nature. 351 (6323): ... 1994). "Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior ... 1996). "Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus ...
Ling X, Ma G, Sun T, Liu J, Arlinghaus RB (January 2003). "Bcr and Abl interaction: oncogenic activation of c-Abl by ... Takizawa Y, Kinebuchi T, Kagawa W, Yokoyama S, Shibata T, Kurumizaka H (September 2004). "Mutational analyses of the human ... Shaul Y (2000). "c-Abl: activation and nuclear targets". Cell Death Differ. 7 (1): 10-6. doi:10.1038/sj.cdd.4400626. PMID ... through the activation loop". FEBS Lett. 469 (1): 72-6. doi:10.1016/S0014-5793(00)01242-4. PMID 10708759. Yano H, Cong F, Birge ...
In a 2007 analysis it was shown that, when modern statistical methods for correcting for the effects of body size and phylogeny ... It is believed that the impact of alcohol on aging can be partly explained by alcohol's activation of the HPA axis, which ... January 2020). "Multifeature analyses of vascular cambial cells reveal longevity mechanisms in old Ginkgo biloba trees". ... de Magalhães JP, Costa J, Church GM (February 2007). "An analysis of the relationship between metabolism, developmental ...
... activation mechanism by running 7.2 µs of molecular dynamics (MD) simulations. Based on homology to G protein-coupled receptor ... Our MD analysis suggests that constitutive activation might arise from the D1073.49-R1083.50 ionic lock destabilization in R ... A3 adenosine receptor activation mechanisms: molecular dynamics analysis of inactive, active, and fully active states Antonella ... A3 adenosine receptor activation mechanisms: molecular dynamics analysis of inactive, active, and fully active states Antonella ...
Proteomic analysis of total and phosphorylated (pT68) Chk2 shows high endogenous levels of Chk2 activation in several cancer ... CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US ... CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US ... Exon array analysis of CHEK2 transcript in the NCI-60 reveals novel splice variants and premature transcript truncation in the ...
Emotion, Influence, Activation: The 2017 Sentiment Analysis Symposium. "Emotions give meaning and relevance to experiences and ... And sentiment analysis?. Sentiment analysis can "shine the spotlight on areas that a company can delight its customers" and "be ... Breakthrough Analysis. Seth Grimes on NLP, text analytics, sentiment analysis, BI, visualization and more. ... Posted in conference, emotion analytics, industry, innovation, sentiment analysis, text analyticsBy SethGrimesLeave a comment ...
... strongly associated with T cell activation in psoriasis. Functional analyses of the gene expression profiles also revealed new ... Using weighted correlation analysis we identified SPATS2L and KLF6 coexpression networks, which were also significantly ... The objective of the present study was to characterize the main genetic pathways associated with T cell activation in psoriasis ... Finally, using Gene Set Enrichment Analysis over the global T cell transcriptome we also found additional genetic pathways ...
Single-cell transcriptomics and protein expression analyses of salivary glands and gingiva, along with the detection of ... Immune cell activation analysis. Immune activation signatures were extracted from MSigDB and scored using scanpy.tl.score_genes ... Gene set (MSigDB) analysis for immune activation pathways (d) does not show clear enrichment, pointing to cells being in a ... MSigDB analysis revealed minimal activation of T, natural killer and B cell populations. For gene lists related to a-d, see ...
MMP9 mRNA and protein levels were measured by quantitative RT-PCR and Western blot analysis, respectively, and MMP9 activity ... Ligand activation of TLR4 activates nuclear factor-kappaB (NF-κB) and the transcription of NF-κB-regulated inflammatory ... However, the mechanism responsible for the effect of LPA on the expression and activation of MMP9 has not been fully elucidated ... of cells with TLR4-siRNA-2 or treatment with CAPE significantly inhibited the upregulated MMP9 expression and activation. This ...
Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID ... Using immunophenotyping, RNA sequencing, and serum cytokine analysis, we analyzed serial samples from 207 SARS-CoV2-infected ...
Analysis of Ashkenazi Jewish Cohort Uncovers New Genetic Loci Linked to Alzheimers Disease The study in Alzheimers & Dementia ... The analysis, the researchers noted, sheds light on the immune environment of the CSF, both in healthy individuals and in ... Sequencing Analysis Examines Gene Regulatory Networks of Honeybee Soldier, Forager Brains Researchers in Nature Ecology & ... T Cell Gene Expression In Multiple Sclerosis CSF Reflects Elevated Activation, Cytotoxicity Sep 18, 2020 , staff reporter ...
Peptide Fragments / analysis * Peptide Hydrolases / analysis * Proteoglycans / physiology * Prothrombin / analysis * Skin / ... Effects of skin mast cells on bleeding time and coagulation activation at the site of platelet plug formation Thromb Haemost. ...
An Activation Likelihood Estimation Meta-Analysis 의 이용 수, 등재여부, 발행기관, 저자, 초록, 목차, 참고문헌 등 논문에 관한 다양한 정보 및 관련논문 목록과 논문의 분야별 BEST ... Methods We performed the experiment by activation likelihood estimation (ALE) software to analysis the differences between ... Regional Homogeneity Brain Alterations in Schizophrenia: An Activation Likelihood Estimation Meta-Analysis ... 대한신경정신의학회 Psychiatry Investigation 제18권 제8호 Regional Homogeneity Brain Alterations in Schizophrenia: An Activation Likelihood ...
Quantitative real-time RT-PCR. Quantitative real-time RT-PCR analysis of the SMAD7 and PAI-1 genes was performed using total ... A key feature of TGF-β signaling activation in cancer cells is the sustained activation of SMAD complexes in the nucleus; ... Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis. Jianfei Xue,1 Xia Lin,2 Wen-Tai Chiu,1 ... Deletion of FOXM1 in Foxm1fl/fl MEFs abolished the effect of TGF-β1 on activation of SBE4-Luc, whereas reexpression of FOXM1 ...
Epithermal instrumental neutron activation analysis (EINAA) has been used to determine the iodine content of many individual ... Determination of iodine in Libyan food samples using epithermal instrumental neutron activation analysis.. ... epithermal instrumental neutron activation analysis (INAA). Link/DOI: http://journals.humanapress.com/index.php?option=com_ ...
Evaluation of a Reduced Pressure Backflow Preventer Using Activation Analysis Description: Report containing tests performed to ... Environmental Analysis of NS Savannah Operation at Camden Description: Report regarding the nuclear ship Savannah and the ...
... ... The time required for total dissolution of bovine tissue was measured and recorded for statistical analysis. Results and ... To analyze the time required to dissolute the pulp tissue under different methods of sodium hypochlorite activation. Material ... no difference between the use of ultrasound and manual activation of the irrigating solution was found. ...
Comparative analyses of length and thickness of filopodia show that our numerical simulations are in agreement with ... A Phenomenological Particle-Based Platelet Model for Simulating Filopodia Formation During Early Activation ... A Phenomenological Particle-Based Platelet Model for Simulating Filopodia Formation During Early Activation ... model can deform to emulate the complex shape change and filopodia formation that platelets undergo during activation. The ...
NEUTRON ACTIVATION ANALYSIS; SEAWATER; X-RAY FLUORESCENCE ANALYSIS; 540230; 540300; RADIOACTIVE MATERIALS MONITORING AND ... Analysis of such material is a routine matter for most geochemists but represents a ``baseline sample`` for marine pollution ... Analysis of such material is a routine matter for most geochemists but represents a ``baseline sample`` for marine pollution ... 54 ENVIRONMENTAL SCIENCES; SEDIMENTS; INTERLABORATORY COMPARISONS; ISOTOPE RATIO; CHEMICAL ANALYSIS; EXPERIMENTAL DATA; IAEA; ...
Importantly, we showed that EGFR-phosphorylated PFKP Y64 has a critical role in AKT activation and AKT-mediated β-catenin S552 ... Importantly, we showed that EGFR-phosphorylated PFKP Y64 has a critical role in AKT activation and AKT-mediated β-catenin S552 ... These findings highlight a novel mechanism underlying a glycolytic enzyme-mediated β-catenin activation and underscore the ... phosphorylation and subsequent β-catenin activation and tumor cell migration, invasion, proliferation, and brain tumor growth. ...
... ... Large-activation-energy asymptotic techniques are used to describe the effects of non-unity Lewis numbers of the fuel on strain ... In our asymptotic analysis the flame structure near extinction is, at leading order, given by the Burke-Schumann limit of ... diffusion-controlled combustion; activation-energy asymptotics; non-unity lewis number; diffusion-flame extinction; premixed- ...
Immune Cell Activation. Activation of Immune Cells for Cytokine Production. Explore ways to activate human and mouse T cells. ... Cell Fixation/Permeabilization Kits for Intracellular Cytokine Analysis. Find protocols for fixing and permeabilizing cells ... Choosing the Right Fix Perm Kits Cell Fixation/Permeabilization Kits for Intracellular Cytokine Analysis. Explore three cell ... Procedure for Manual Setting of Compensation for Multi-Color Flow Cytometric Analysis. Find detailed information on electronic ...
In vivo prompt gamma neutron activation analysis for the screening of boron-10 distribution in a rabbit knee: a simulation ... In vivo prompt gamma neutron activation analysis for the screening of boron-10 distribution in a rabbit knee: a simulation ...
Dive into the research topics of Study of CdTe/CdS-thin films by isotope dilution, neutron activation analysis, inductively ... Study of CdTe/CdS-thin films by isotope dilution, neutron activation analysis, inductively coupled plasma mass spectrometry and ...
Analysis of the Involvement of NMDA Receptors in Analgesia and Hypothermia Induced by the Activation of TRPV1 Ion Channels ... Analysis of the Involvement of NMDA Receptors in Analgesia and Hypothermia Induced by the Activation of TRPV1 Ion Channels - ... Analysis of the Involvement of NMDA Receptors in Analgesia and Hypothermia Induced by the Activation of TRPV1 Ion Channels , ...
Analysis of the pattern of subcellular force generation by corneal fibroblasts after Rho activation. In: Eye and Contact Lens. ... Analysis of the pattern of subcellular force generation by corneal fibroblasts after Rho activation. / Petroll, W. Matthew; Ma ... title = "Analysis of the pattern of subcellular force generation by corneal fibroblasts after Rho activation", ... Analysis of the pattern of subcellular force generation by corneal fibroblasts after Rho activation. ...
2018). MicroRNA expression analysis of in vitro dedifferentiated human pancreatic islet cells reveals the activation of the ... 2018). MicroRNA expression analysis of in vitro dedifferentiated human pancreatic islet cells reveals the activation of the ... MicroRNA expression analysis of in vitro dedifferentiated human pancreatic islet cells reveals the activation of the ... Bioinformatic analysis indicated that miR-302s are predicted to target several genes involved in the control of β-cell/ ...
Patient Activation for Self-Management of Chronic Conditions (R01 Clinical Trial Optional) PAR-19-381. NINR ... Data Management and Statistical Analysis Are planned analyses and statistical approach appropriate for the proposed study ... Yet how to increase patient activation, including the use of strategies that work within the context of social determinants of ... One means to address this problem is patient activation, a key behavioral indicator of self-management. Being activated refers ...
WHOLE ROCK ANALYSIS. XRF X-ray Fluorescence. INAA Instrumental Neutron Activation Analysis. ICP Inductively-coupled plasma ... FLUID ANALYSIS. Heating freezing microscope stage. Atomic Absorption spectrometer. Gas Chromatography. OTHER. Thermal Analysis ... Title of your instrument (e.g. "An Integrated AES, EDS,EBSD Imaging and Analysis System"). Manufacturer and Model. Instrument ... Trace element analysis. Structure (atomic) of minerals (diffraction methods). Surface chemistry (sorption, catalysis). Depth ...
Keyword:ReLU Activation Function. Papers. Acoustic Scene Analysis and Classification Using Densenet Convolutional Neural ...
  • We determined the element by neutron activation analysis in 30 individuals. (nih.gov)
  • Determination of iodine in Libyan food samples using epithermal instrumental neutron activation analysis. (lml.com.ly)
  • Epithermal instrumental neutron activation analysis (EINAA) has been used to determine the iodine content of many individual food materials that constitute the typical Libyan diet. (lml.com.ly)
  • In vitro transcriptional activation (TA) assays are based upon the production of a reporter gene product induced by a chemical, following binding of the chemical to a specific receptor and subsequent downstream transcriptional activation. (nih.gov)
  • Importantly, we showed that EGFR-phosphorylated PFKP Y64 has a critical role in AKT activation and AKT-mediated β-catenin S552 phosphorylation and subsequent β-catenin transactivation and promotion of tumor cell glycolysis, migration, invasion, proliferation, and brain tumor growth. (frontiersin.org)
  • In the present study, we apply the framework of transition path theory (TPT) to the previously constructed MSM to characterize the main features of the activation pathway. (nih.gov)
  • We developed a phenomenological three-dimensional platelet model to characterize the filopodia formation observed during early stage platelet activation. (nih.gov)
  • Systematic single-cell pathway analysis to characterize early T cell activation. (nih.gov)
  • Hepatocytes that were unable to attach to a collagen matrix showed many signs of cellular stress, including a glycolytic phenotype and activation of the heat shock response, ultimately leading to apoptosis activation. (springer.com)
  • Many of these genes were linked to T cell activation, cytotoxicity, and an effector phenotype. (genomeweb.com)
  • Kinetic and equilibrium isotope effects and entropies of activation and reaction were investigated as a function of the increasing size of the Hessian, as the system is expanded to include not only the atoms of chorismate/prephenate itself but also an increasing number of surrounding water molecules (up to 99) or active-site residues (up to 225 atoms). (bath.ac.uk)
  • The time required for total dissolution of bovine tissue was measured and recorded for statistical analysis. (bvsalud.org)
  • NIEHS is establishing an infrastructure, the Children's Health Exposure Analysis Resource (CHEAR), to provide the extramural research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research. (nih.gov)
  • The network has three units, a National Exposure Assessment Laboratory Network and an Exposure Data Repository and Resource for Statistical Analysis and Methods Development, as well as a coordinating center. (nih.gov)
  • MMP9 mRNA and protein levels were measured by quantitative RT-PCR and Western blot analysis, respectively, and MMP9 activity was measured by zymography. (medscimonit.com)
  • Results Thirteen functional imaging studies were included in quantitative meta-analysis. (kyobobook.co.kr)
  • Here, we demonstrate that phosphofructokinase 1 platelet isoform (PFKP), which catalyzes a rate-limiting reaction in glycolysis, promotes EGFR activation-induced nuclear translocation and activation of β-catenin, thereby enhancing the expression of its downstream genes CCND1 and MYC in human glioblastoma cells. (frontiersin.org)
  • The NEI Research Grant for Secondary Data Analysis (R21) program is designed to provide investigators with the support necessary to conduct secondary data analyses utilizing existing database resources. (nih.gov)
  • The purpose of this mechanism is to provide limited support for meritorious research projects that involve secondary data analyses using existing database resources. (nih.gov)
  • Each laboratory center (defined in this FOA as a Hub) within the network will provide analysis of environmental and endogenous exposures through both targeted and untargeted approaches. (nih.gov)
  • Magnetic Resonance Imaging of Human Brain Activation using Endogenous Susceptibility Contrast. (nih.gov)
  • EGFR activation-induced and CK2α-mediated α-catenin phosphorylation releases β-catenin from the β-catenin/α-catenin protein complex whereas nuclear pyruvate kinase M2 (PKM2) associates with β-catenin and induces gene expression by direct phosphorylation of histone H3 ( 12 - 17 ). (frontiersin.org)
  • To analyze the time required to dissolute the pulp tissue under different methods of sodium hypochlorite activation. (bvsalud.org)
  • Meta-Analysis by Marinovich et al . (nih.gov)
  • A comprehensive single cell data analysis of lymphoblastoid cells reveals the role of super-enhancers in maintaining EBV latency. (nih.gov)
  • Single-cell analysis of lizard blastema fibroblasts reveals phagocyte-dependent activation of Hedgehog-responsive chondrogenesis. (nih.gov)
  • The purpose of this Funding Opportunity Announcement is to encourage grant applications that address the influence of patient activation on self-management of chronic conditions. (nih.gov)
  • Here, we release a working version of TbCAPs, a new toolbox for CAP analysis , which includes all steps of the analytical pipeline, introduces new methodological developments that build on already existing concepts, and enables a facilitated inspection of CAPs and resulting metrics of brain dynamics. (bvsalud.org)
  • Departing from continuum mechanics based approaches, this coarse-grained molecular dynamics (CGMD) particle-based model can deform to emulate the complex shape change and filopodia formation that platelets undergo during activation. (nih.gov)
  • NEW YORK - T cells isolated from the cerebrospinal fluid of people with multiple sclerosis express higher levels of genes linked to T cell activation and cytotoxicity than those from the CSF of healthy people, according to a new single-cell RNA sequencing study. (genomeweb.com)
  • For instance, genes involved in TCR engagement and T cell activation were more highly expressed among MS patients compared to controls. (genomeweb.com)
  • Ligand activation of TLR4 activates nuclear factor-kappaB (NF-κB) and the transcription of NF-κB-regulated inflammatory cytokines, which are involved in the development of atherosclerosis. (medscimonit.com)
  • One notable instance is co-activation pattern (CAP) analysis , a frame-wise analytical approach that disentangles the different functional brain networks interacting with a user-defined seed region. (bvsalud.org)
  • The calculated vibrational entropy of activation for the enzymic reaction agrees well with an experimental value for E. coli chorismate mutase. (bath.ac.uk)
  • 17 β-estradiol (17β-E 2 ) protects human lens epithelial cells against oxidative stress by preserving mitochondrial function in part via the non-genomic rapid activation of prosurvival signal transduction pathways. (molvis.org)
  • Transfection of cells with TLR4-siRNA-2 or treatment with CAPE significantly inhibited the upregulated MMP9 expression and activation. (medscimonit.com)
  • Escapees are aggregates of cells (including positively labeled cells) that are excluded from the flow cytometric analysis gate, thus altering the results of the analysis. (bdbiosciences.com)
  • Methods We performed the experiment by activation likelihood estimation (ALE) software to analysis the differences between people with schizophrenia group (all schizophrenia group and chronic schizophrenia group) and healthy controls. (kyobobook.co.kr)
  • I realize that a group analysis would be preferable but I am looking at pilot data with one subject to get an idea of how this analysis works. (nih.gov)
  • The symposium opens with a day devoted to consumer, market, and media sentiment and emotion analysis presentations and panel - the business case, applications, and technologies - followed by a day of break-out workshops. (breakthroughanalysis.com)
  • In a previous study, we generated a Markov state model (MSM) to simulate the activation of c-Src catalytic domain, used as a prototypical tyrosine kinase. (nih.gov)
  • Large-activation-energy asymptotic techniques are used to describe the effects of non-unity Lewis numbers of the fuel on strain-induced extinction of axisymmetric counterflow diffusion flames. (uc3m.es)
  • The Collection and Preparation of Human Blood Plasma or Serum for Trace Element Analysis. (nih.gov)
  • The Children's Health Exposure Analysis Resource (CHEAR) is a multi-unit infrastructure to provide access to comprehensive exposure analysis that can be performed using biological samples collected in studies of children's health. (nih.gov)
  • Western blot analysis was used to examine the pattern of protein expression as influenced by 17β-E 2 treatment. (molvis.org)
  • TbCAPs: A toolbox for co-activation pattern analysis. (bvsalud.org)
  • Follow-up (~5 years) and primary data analysis (~1 year) will add ~6 years after enrollment i.e., completion and reporting of the data between 2029 and 2032 (vs. 2025). (nih.gov)
  • Analysis of such material is a routine matter for most geochemists but represents a ``baseline sample`` for marine pollution chemists. (osti.gov)
  • Multilevel analyses assessed cross-sectional associations between employee and job characteristics and health in analyses of 1,524 employees in 30 extended-care facilities in a single company. (cdc.gov)
  • However, the mechanism responsible for the effect of LPA on the expression and activation of MMP9 has not been fully elucidated. (medscimonit.com)
  • Moreover, no difference between the use of ultrasound and manual activation of the irrigating solution was found. (bvsalud.org)
  • I went through all of the steps to run context dependent correlation analysis on one subject. (nih.gov)
  • The analysis, the researchers noted, sheds light on the immune environment of the CSF, both in healthy individuals and in people with neuroinflammation. (genomeweb.com)