Infections with bacteria of the order ACTINOMYCETALES.
An order of gram-positive, primarily aerobic BACTERIA that tend to form branching filaments.
A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
Cyanoacrylate tissue adhesive also used to occlude blood vessels supplying neoplastic or other diseased tissue.
A genus of gram-positive, aerobic bacteria whose species are widely distributed and are abundant in soil. Some strains are pathogenic opportunists for humans and animals.
A genus of gram-positive bacteria that forms a branched mycelium. It commonly occurs as a saprophytic form in soil and aquatic environments.
Class of BACTERIA with diverse morphological properties. Strains of Actinobacteria show greater than 80% 16S rDNA/rRNA sequence similarity among each other and also the presence of certain signature nucleotides. (Stackebrandt E. et al, Int. J. Syst. Bacteriol. (1997) 47:479-491)
Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.
A genus of gram-positive, rod-shaped bacteria whose organisms are nonmotile. Filaments that may be present in certain species are either straight or wavy and may have swollen or clubbed heads.
The relationships of groups of organisms as reflected by their genetic makeup.
The presence of bacteria, viruses, and fungi in the soil. This term is not restricted to pathogenic organisms.
DNA sequences encoding RIBOSOMAL RNA and the segments of DNA separating the individual ribosomal RNA genes, referred to as RIBOSOMAL SPACER DNA.
A genus of bacteria that form a nonfragmented aerial mycelium. Many species have been identified with some being pathogenic. This genus is responsible for producing a majority of the ANTI-BACTERIAL AGENTS of practical value.
A genus of asporogenous bacteria that is widely distributed in nature. Its organisms appear as straight to slightly curved rods and are known to be human and animal parasites and pathogens.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
The relative amounts of the PURINES and PYRIMIDINES in a nucleic acid.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Proteins found in any species of bacterium.

Case of sepsis caused by Bifidobacterium longum. (1/351)

We report a case of sepsis caused by Bifidobacterium longum in a 19-year-old male who had developed high fever, jaundice, and hepatomegaly after acupuncture therapy with small gold needles. Anaerobic, non-spore-forming, gram-positive bacilli were isolated from his blood and finally identified as B. longum. He recovered completely after treatment with ticarcillin and metronidazole. To our knowledge, this is the first report of incidental sepsis caused by B. longum.  (+info)

Movement disorders in encephalitis induced by Rhodococcus aurantiacus infection relieved by the administration of L-dopa and anti-T-cell antibodies. (2/351)

Mice injected with Rhodococcus aurantiacus by the intravenous (i.v.) route show neurological disorders, hemiparesis, vertical headshake and turn-round gait after day 7 postinfection (p.i.). Neurological symptoms caused by i.v. inoculation of R. aurantiacus were relieved by treatment with levodopa (l-dopa). R. aurantiacus was isolated from the brain and was found to be completely eliminated at day 7 p. i. Focal encephalitis was mainly observed in the brain stem, and T cells could be isolated from the brain after day 7 p.i. Administration of both an anti-CD4 monoclonal antibody (mAb) and an anti-CD8 mAb suppressed neurological symptoms. These results suggest that R. aurantiacus induces movement disorders in mice, and that the symptoms are mediated by T cells infiltrating the brain, rather than directly by the bacterium.  (+info)

Tumour necrosis factor and interferon-gamma are required in host resistance against virulent Rhodococcus equi infection in mice: cytokine production depends on the virulence levels of R. equi. (3/351)

Rhodococcus equi is a facultative intracellular bacterial pathogen that causes pneumonia in foals and immunosuppressed humans. There are at least three virulence levels of R. equi and these pathogenicities are associated, in mice, with the presence of virulence plasmids. This study focused on cytokine secretion, in mice, in the course of a primary infection with sublethal doses of R. equi strains of different virulence levels (virulent, intermediately virulent and avirulent). Tumour necrosis factor (TNF) and interferon-gamma (IFN-gamma), but not interleukin-4 (IL-4) and interleukin-10 (IL-10), were induced endogenously in mice in relation to the multiplication and clearance of virulent and intermediately virulent strains of R. equi. These cytokines were not detected in mice infected with avirulent R. equi. Deaths occurred among mice treated with monoclonal antibodies (mAbs) against either TNF or IFN-gamma prior to sublethal dose infection with virulent and intermediately virulent strains of R. equi, but not with avirulent R. equi. These results suggested that cytokine production depended largely on the virulence levels of R. equi: TNF and IFN-gamma were required early during infection with virulent R. equi to limit replication and clearance of bacteria within the organs, but they were not necessary for limiting infection with avirulent R. equi.  (+info)

Infection by Rhodococcus equi in a patient with AIDS: histological appearance mimicking Whipple's disease and Mycobacterium avium-intracellulare infection. (4/351)

Rhodococcus equi pneumonia with systemic dissemination is being reported increasingly in immunocompromised patients. This is the first case report of disseminated R equi infection with biopsy documented involvement of the large intestine. The patient was a 46 year old male with AIDS who was diagnosed with cavitating pneumonia involving the left lower lobe. R equi was isolated in culture from the blood and lung biopsies. Subsequently, the patient developed anaemia, diarrhoea, and occult blood in the stool. Colonoscopy revealed several colonic polyps. Histological examination of the colon biopsies showed extensive submucosal histiocytic infiltration with numerous Gram positive coccobacilli and PAS positive material in the histiocytes. Electron microscopy showed variably shaped intrahistiocytic organisms which were morphologically consistent with R equi in the specimen. Disseminated R equi infection may involve the lower gastrointestinal tract and produce inflammatory polyps with foamy macrophages which histologically resemble those seen in Whipple's disease and Mycobacterium avium-intracellulare infection.  (+info)

Role of the 85-kilobase plasmid and plasmid-encoded virulence-associated protein A in intracellular survival and virulence of Rhodococcus equi. (5/351)

Rhodococcus equi is a facultative intracellular pathogen of macrophages and a cause of pneumonia in young horses (foals) and immunocompromised people. Isolates of R. equi from pneumonic foals typically contain large, 85- or 90-kb plasmids encoding a highly immunogenic virulence-associated protein (VapA). The objective of this study was to determine the role of the 85-kb plasmid and VapA in the intracellular survival and virulence of R. equi. Clinical isolates containing the plasmid and expressing VapA efficiently replicated within mouse macrophages in vitro, while plasmid-cured derivatives of these organisms did not multiply intracellularly. An isolate harboring the large plasmid also replicated in the tissues of experimentally infected mice, whereas its plasmid-cured derivative was rapidly cleared. All foals experimentally infected with a plasmid-containing clinical isolate developed severe bronchopneumonia, whereas the foals infected with its plasmid-cured derivative remained asymptomatic and free of visible lung lesions. By day 14 postinfection, lung bacterial burdens had increased considerably in foals challenged with the plasmid-containing clinical isolate. In contrast, bacteria could no longer be cultured from the lungs of foals challenged with the isogenic plasmid-cured derivative. A recombinant, plasmid-cured derivative expressing wild-type levels of VapA failed to replicate in macrophages and remained avirulent for both mice and foals. These results show that the 85-kb plasmid of R. equi is essential for intracellular replication within macrophages and for development of disease in the native host, the foal. However, expression of VapA alone is not sufficient to restore the virulence phenotype.  (+info)

Disseminated Rhodococcus equi infection in two goats. (6/351)

Rhodococcus equi infection was diagnosed in two goats from the same herd. At necropsy, numerous caseating granulomas were disseminated throughout the liver, lungs, abdominal lymph nodes, medulla of right humerus, and the right fifth rib of goat No. 1, and the liver of goat No. 2. Histopathologic examination confirmed the presence of multiple caseating granulomas in these organs. Numerous gram-positive and Giemsa-positive coccobacilli were identified within the cytoplasm of macrophages. Aerobic bacterial cultures of the liver and lung from both goats yielded a pure growth of R. equi. R. equi antigens were immunohistochemically identified in caseating granulomas from both goats. However, the 15- to 17-kd virulence antigens of R. equi were not detected, suggesting possible infection by an avirulent strain of this organism.  (+info)

TNF receptor p55 is required for elimination of inflammatory cells following control of intracellular pathogens. (7/351)

The elimination of lymphocytes within inflammatory lesions is a critical component in the resolution of disease once pathogens have been cleared. We report here that signaling through the TNF receptor p55 (TNFRp55) is required to eliminate lymphocytes from lesions associated with intracellular pathogens. Thus, TNFRp55-/- mice, but not Fas-deficient mice, maintained inflammatory lesions associated with either Leishmania major or Rhodococcus equi infection, although they developed a Th1 response and controlled the pathogens. Inflammatory cells from either L. major- or R. equi-infected C57BL/6 mice were sensitive to TNF-induced apoptosis, and conversely the number of apoptotic cells in the lesions from TNFRp55-/- mice was dramatically reduced compared with wild-type mice. Furthermore, in vivo depletion of TNF in wild-type mice blocked lesion regression following R. equi infection. Taken together, our results suggest that signaling through the TNFRp55, but not Fas, is required to induce apoptosis of T cells within inflammatory lesions once pathogens are eliminated, and that in its absence lesions fail to regress.  (+info)

Modulation of cytokine response of pneumonic foals by virulent Rhodococcus equi. (8/351)

The ability of Rhodococcus equi to induce pneumonia in foals depends on the presence of an 85- to 90-kb plasmid. In this study, we evaluated whether plasmid-encoded products mediate virulence by modulating the cytokine response of foals. Foals infected intrabronchially with a virulence plasmid-containing strain of R. equi had similar gamma interferon (IFN-gamma) and interleukin-12 (IL-12) p35 but significantly higher IL-1beta, IL-10, IL-12 p40, and tumor necrosis factor alpha (TNF-alpha) mRNA expression in lung tissue compared to foals infected with the plasmid-cured derivative. IFN-gamma mRNA expression levels in CD4+ T lymphocytes isolated from bronchial lymph nodes (BLN) were similar for the two groups of R. equi-infected foals on day 3 postinfection. However, on day 14, in association with pneumonia and marked multiplication of virulent R. equi but with complete clearance of the plasmid-cured derivative, IFN-gamma mRNA expression in BLN CD4+ T lymphocytes was significantly (P < 0.001) higher in foals infected with the plasmid-cured derivative. These results suggests an immunomodulating role for R. equi virulence plasmid-encoded products in downregulating IFN-gamma mRNA expression by CD4+ T lymphocytes.  (+info)

Serum antibody titres to Dermatophilus congolensis demonstrated by an enzyme-linked immunosorbent assay (ELISA) in young steers and in adult cows from an Ayrshire herd showed a bimodal distribution and provided evidence of subclinical infection. Very high titres detected in sera from crossbred Galloway steers were indicative of recent or existing infection which may have been masked by concurrent ringworm. The ELISA is a sensitive and technically simple method which enables sera to be screened for evidence of infection by D congolensis which may otherwise pass unrecognised. Such infections may be of importance not only in the epidemiology of the disease in farm animals but also as a potential source of infection for man and his domestic pets.. ...
Mud fever, also known as scratches or pastern dermatitis, is a group of diseases of horses causing irritation and dermatitis in the lower limbs of horses. Often caused by a mixture of bacteria, typically Dermatophilus congolensis, and Staphylococcus spp, mud fever can also be caused by fungal organisms (dermatophytes). Photosensitization, chorioptic mange mites, contact dermatitis and other conditions also contribute to some cases. This condition is also known as dew poisoning, grease heel, or greasy heel. Mud fever affects most horses and ponies during winter and early spring, resulting in painful sores and scabs, which in severe cases can make a horse lame. Mud fever most commonly affects the pastern and heel area but can also affect the upper leg, the belly, and in some cases the neck area (also known as Rain Scald). Non-pigmented skin tends to be more severely affected. Mud fever is caused by an infection of the skin by bacteria, including Dermatophilus congolensis, and often Staphylococcus ...
An investigation into potential disinfectant agents that could be used on farms to reduce environmental virulent Rhodococcus equi burdens. - Research Supervisor Connect - University of Sydney, Australia
A new study challenges the belief that polysynovitis and uveitis are immune-mediated processes in foals infected with Rhodococcus equi.
Rhodococcus equi was previously thought to be exclusively an equine pathogen, but in recent years Rhodococcus equi infection is occurring with increasing frequency in humans [15]. Infection in a human was first reported in 1967 in a 29-year-old man with plasma cell hepatitis receiving immunosuppressant medications [10]. It is found exclusively in immunocompromised individuals, such as those with AIDS, small cell carcinoma of the lung, malignant lymphoma, or recipients of kidney or bone marrow transplants [19].. The organism is particularly susceptible to erythromycin and clindamycin; the aminoglycosides, amikacin, gentamycin, neomycin and tobromycin, rifampin and vancomycin [15]. It is moderately susceptible to penicillin G, ampicillin and tetracyclines, and is usually moderately susceptible or resistant to first and second generation cephalosporins [15].. As determined by FIC (fractional inhibitory concentration) indices, four combinations were synergistic: rifampin-erythromycin, ...
The conjugative virulence plasmid is a key component of the Rhodococcus equi accessory genome essential for pathogenesis. Three host-associated virulence plasmid types have been identified: the equine pVAPA and porcine pVAPB circular variants, and the linear pVAPN found in bovine (ruminant) isolates. We recently characterized the R. equi pangenome (Anastasi E, et al. 2016. Pangenome and phylogenomic analysis of the pathogenic actinobacterium Rhodococcus equi. Genome Biol Evol. 8:3140-3148.) and we report here the comparative analysis of the virulence plasmid genomes. Plasmids within each host-associated type were highly similar despite their diverse origins. Variation was accounted for by scattered single nucleotide polymorphisms and short nucleotide indels, while larger indels-mostly in the plasticity region near the vap pathogencity island (PAI)-defined plasmid genomic subtypes. Only one of the plasmids analyzed, of pVAPN type, was exceptionally divergent due to accumulation of indels in the ...
Rhodococcus equi, (previously known as Corynebacterium equi) causes a persistent bacterial pneumonia in foals, and may become established as an endemic disease on some breeding farms. It may result in considerable losses through costs of diagnosis and treatment, and in some cases, through death. A better understanding of the disease may reduce its significance.
Dermatophilus congolensis is a gram positive bacterium which causes a skin disease in a wide range of animals including man. This disease is called dermatophilosis, commonly known as rain rot. Dermatophilosis causes extensive damage within the animal industry, including loss of days at work, reduction in milk yield, and deterioriation of hide and meat quality. This disease requires quick diagnostic tools and sustainable treatment to avoid economic losses. ^ The 1029 bp DNA segment of the alkaline ceramidase gene of D. congolensis was targeted to develop a species-specific PCR to speed up the diagnostic and treatment process to minimize economic losses. The PCR is sensitive, specific and detects as low as 50 × 10-3µg of D. congolensis DNA within 4 hours. This PCR has potential clinical application for rapid diagnosis of dermatophilosis. ^ Caprylic acid is a medium chain fatty acid that contains 8 carbons in its structure. Caprylic acid and its derivatives, namely monocaprylin and sodium caprylate, are
Rhodococcus equi (R. equi) is an intracellular, gram-positive coccobacillus that causes pneumonia in foals aged 2 to 4 months. Neonatal foals are susceptible to R. equi infection probably due to inefficient Toll-like receptor (TLR)-2 signaling and inability to produce interferon gamma. One of the reasons for inefficient receptor signaling and recognition of R. equi by the foals immune system may be the inefficient sequestration of TLRs in lipid rafts, which act as signaling platforms. However, there are no protocols to isolate lipid rafts from equine cells and, therefore, no data on the association of TLRs with the lipid rafts in the lung cells of normal and infected foals. Because of the clinical importance of the disease, there is considerable interest in developing effective prophylactic methods, which in turn requires a better understanding of fundamental immunology of the foals. In this study, I have examined the effect of R. equi vaccination on the lung inflammation induced following ...
The response of the intracellular pathogen Rhodococcus equi to H(2)O(2) treatment, a situation potentially encountered after the oxidative burst of alveolar macrophages, was analyzed. Compared to other bacteria, including Deinococcus radiodurans, R. equi showed exceptionally high resistance to this stress. A proteomic approach showed that four polypeptides present in the wild-type strain (85F) are missing in the plasmid-cured strain 85F(P-), and by using a DNA macroarray, we identified two plasmid-encoded vap genes, vapA and vapG, whose expression was highly induced by H(2)O(2) treatment. Whereas the transcript size of vapA was compatible with a monocistronic mRNA, the transcript of vapG was considerably longer. Rapid amplification of cDNA ends PCRs showed that the transcriptional start sites of the two operons were 69 and 269 nucleotides (nt) upstream of the start codon, respectively. Analysis of these leader sequences revealed the presence of a small open reading frame named podG, which ...
Rhodococcus equi is a Gram-positive aerobic coccobacillus of the Corynebacteriales associated with chronic or subacute pyogenic infections (1, 2). A normal soil inhabitant, the bacterium uses manure as a growth substrate, multiplies in the herbivores large intestine, and is ubiquitous in the farm environment. Transmission occurs via contaminated dust particles, mostly through airborne exposure (3, 4). R. equi is the causative agent of a major infectious disease of horses that affects young foals worldwide. The infection is characterized by multifocal purulent bronchopneumonia, often accompanied by ulcerative or abcessating lesions in the intestine (1, 5). While best known as an equine pathogen, R. equi also infects other animal species (1, 6-8). In abattoir surveys, R. equi is frequently recovered from porcine submaxillary lymph nodes with granulomatous lesions as well as from apparently healthy pigs (9-11). In cattle, it is typically isolated from caseating abscesses in respiratory lymph nodes ...
A vaccine for Rhodococcus equi, the common bacteria that affects foals, often causing severe infections, pneumonia, and sometimes death, is in the final stages of development. Intervet/Schering-Plough Animal Health (ISPAH) said on Jan. 27 that a candidate vaccine for R. equi would be tested in a field trial in Germany in the near future.
Screening for Rhodococcus Equi ADRPresented by Dr. Richard MarkellCellulitisPresented by Dr. Phoebe SmithFoal DiarrheaPresented by Dr. Bonnie BarrLamin...
FINAL DIAGNOSIS. PNEUMONIA, HILAR LYMPHADENITIS, AND SEPSIS SECONDARY TO Rhodococcus equi. Rhodococcus equi, originally identified by Magnusson as an agent capable of causing a granulomatous infection in horses in 1923,1,2 is an increasingly recognized opportunistic pathogen of humans. Since the initial description by Golub et al 3 initial description of R. equi infection in humans in 1967, more than 100 cases have been reported in the literature.2 While the organism primarily afflicts patients with impaired cellular immunity, cases have been described in patients with no known underlying predisposing condition.. R. equi is a water and soil organism which is most commonly found in environments associated with domesticated animals, whose manure provide required nutritional support for these organisms.4 Human infection is believed to occur secondary to the exposure of a susceptible individual to the appropriate environment. In the present case, the patient had a farm where he raised 27 horses ...
Members of genus Gordonia are widely distributed in nature, and about 29 species have been identified. From 1996 to 2015, only 16 cases of infections caused by Gordonia sputi were reported worldwide, most of which were catheter related, such as contaminated central venous catheters and chest tubes, in a setting of immunocompromised status [7-9]. Gordonia spp. infection usually has a subacute or chronic course, sometimes resembling fungi infection. The patient in this case presented with vision blurred about 10 days after the iron foreign body penetrating, showing multiple clusters of white purulent lesions in the anterior chamber, vitreous cavity and on the retina, without obvious pain, which might clinically indicate a less virulent bacteria or fungi infection. According to the contemporary gram stain and its reaction to intravitreal antibiotic a gram-positive bacilli infection was presumed, and further molecular examinations confirmed the pathogen as Gordonia sputi. So, when facing a subacute ...
It isn't for lack of effort that the equine industry still doesn't have new options for treating Rhodococcus equi pneumonia in foals. According to Noah Cohen, VMD, MPH, PhD, Dipl. ACVIM, professor of equine medicine at Texas A&M University, he and his colleagues are well aware that veterinarians are in dire need of better antibiotic alternativ.... ...
Abstract: Aim: To study the prevalence of Theileria equi among horses in different age groups, both sexes, months and seasons of the year, and regions of Giza governourate. Studying the changes in the blood picture, blood chemistries, liver enzymes associate with T.equi infections in horses. Evaluating IFA and CFT at different dilutions in the serodiagnosis of T.equi infections in horses. Evaluating four anti-Theileria medication regimens (diminazine aceturate, imidiocarb 7%, buparvaquone and a combination of imidiocarb 7% and buparvaquone) in treatment of T.equi infections in horses. Materials and Methods: Total of 149 horses were examined by clinical signs and blood smears. Fortey whole blood samples from T.equi infected horses were examined to measure haemoglobin, total RBCs count and PCV. Fortey serum samples from T.equi infected horses were examined to measure total bilirubin, direct bilirubin, ALT and AST enzymes. Serum samples from T.equi infected (40) and non infected (14) horses were ...
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Jade L. L. Teng, Ying Tang, Tsz Ho Chiu, Candy L. W. Cheung, Antonio H. Y. Ngan, Cheung Ngai, Samson S. Y. Wong, Tak-Lun Que, Susanna K. P. Lau, Patrick C. Y. Woo ...
Arcanobacterium pyogenes Pyolysin: member of thiol-activated cytolysin family; isolated from Arcanobacterium pyogenes; amino acid sequence in first source; GenBank U84782
Arcanobacterium haemolyticum ATCC ® BAA-1784™ Designation: Vitek 1656 TypeStrain=False Application: Quality control strain
Arcanobacterium haemolyticum ATCC ® BAA-1784™ Designation: Vitek 1656 TypeStrain=False Application: Quality control strain
TY - JOUR. T1 - Sicca syndrome associated with Tropheryma whipplei intestinal infection. AU - Bosman, Cesare. AU - Boldrini, Renata. AU - Borsetti, Giuliana. AU - Morelli, Sergio. AU - Paglia, Maria Grazia. AU - Visca, Paolo. PY - 2002/8/1. Y1 - 2002/8/1. N2 - The case of a 61-year-old woman with Whipples disease-associated sicca complex is reported. Tropheryma whipplei infection was diagnosed by histological and ultrastructural examination of the jejunal mucosa and sequence analysis of the bacterial 16S ribosomal DNA. The role of vitamin A malabsorption in sicca complex secondary to Whipples disease is discussed.. AB - The case of a 61-year-old woman with Whipples disease-associated sicca complex is reported. Tropheryma whipplei infection was diagnosed by histological and ultrastructural examination of the jejunal mucosa and sequence analysis of the bacterial 16S ribosomal DNA. The role of vitamin A malabsorption in sicca complex secondary to Whipples disease is discussed.. UR - ...
As base substitutions within domain V of the 23S rRNA can result in ML resistance (17), sequencing of this gene region in these A. pyogenes isolates was undertaken. Primers 23S-1 (5′-AGTTCCGACCTGCACGAATGGC-3′) and 23S-2 (5′-GTTCGTCCGTCCCGGTCCTCTC-3′) were used to amplify a product of 728 bp, equivalent to bases 1953 to 2680 of the E. coli 23S rRNA gene (GenBank accession no. U70214 ), from the four macrolide-resistant and three macrolide-susceptible A. pyogenes isolates. The sequences of the PCR products were determined by using automated DNA sequencing.. Mutations were identified by aligning the sequences using CLUSTAL W (13), with the sequence of the MLsA. pyogenes isolate BBR1 being designated the wild type. Of the other MLs isolates, OX-5 has a wild-type sequence and OX-9 has a G2137T substitution (E. coli numbering). As OX-9 is MLs, it is unlikely that the G2137T change contributes to ML resistance, and it probably represents a naturally occurring polymorphism in the 23S rRNA ...
Enda joined the National Centre for Biomedical Engineering Science in 2005 from the School of Biomolecular and Biomedical Science and Conway Institute of Biomolecular and Biomedical Research at University College Dublin. He holds a B.Sc. in Industrial Microbiology and a Ph.D. in Molecular Microbiology from UCD, where he studied the regulation of virulence gene expression in the intracellular equine pathogen Rhodococcus equi.. In his role as Senior Technical Officer, Enda provides training and support for researchers in Functional Genomics and Molecular Biology techniques, to examine gene expression and regulation. These include Microarray and Real Time PCR technology, RNA Isolation and QC, Experimental Design and Microarray Data Analysis using the GeneSpring GX data analysis package.. Enda also provides support for the recently established NCBES High Throughput Screening facility, where Drug Discovery and Characterisation, Cellular, Enzymatic and Binding Assays, as well as Sample Analysis may be ...
Background:Tropheryma whipplei causes acute diseases, such as gastroenteritis, bacteremia, and pneumonia (1), as well as chronic Whipple disease (2). It can be cultivated from stool samples, which are a potential source of infection (3). Detection of T. whipplei DNA in saliva also suggests an oral-oral method of transmission. However, cultivation of T. whipplei from saliva has been impossible because of heavy contamination by other bacteria ...
The bacterium Rhodococcus equi has been a known cause of life-threatening pneumonia in foals for many years. But the ideal treatment for R. equi infection remains debatable because of the lack of research comparing the efficacy of each possible treat
A Guide for Adults with Kidney Disease, Kidney Failure, or a Kidney Transplant Why do I need a vaccination? English Spanish Vaccines help keep you from getting a serious disease. They protect you from many common diseases, like the flu, diphtheria, tetanus, hepatitis B and pneumonia. Many of these diseases can make you very sick and cause death.
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Cell and Molecular Biology. Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Cell and Molecular Biology. IMMUNOLOGY PROGRAMME. ...
Rhodococcus equi is a gram-positive, pleomorphic coccobacillus that is a frequent cause of pneumonia and enteritis in foals, especially before 6 months of age. It has also been linked to a variety of suppurative processes in immune-suppressed humans (Prescott, 1991). The organism has a worldwide distribution and can easily be isolated from soil and environmental samples (Barton and Hughes, 1984; Debey and Bailie, 1987; Takai et al., 1991). Pathogenic R. equi isolated from sick foals uniformly contain an 85- to 90-kb plasmid known as vapA, which carries a gene responsible for expression of a 15- to 17-kDa antigen of undetermined function (Takai et al., 1991, 1993). Environmental strains of R. equi not associated with equine disease do not contain this plasmid. ...
57) Abstract:. The invention relates to veterinary Microbiology and can be used in bacteriological laboratories for the preparation of diagnostic kits. The strain obtained using traditional microbiological techniques from the urine of pigs with clinical signs of urocystic and pyelonephritis. The strain is deposited in the Institute of culture collections of microorganisms GMCVB Vector number 0699. Expressed antigenic properties and the ability to quickly and easily multiply on artificial and natural environments make use of this strain as a reference strain in the preparation of diagnostic kits. The invention relates to the field of veterinary Microbiology, epizootiology and can be used in bacteriological laboratories.. In the claimed invention was set the task of finding a strain of bacteria, easy and fast breeding on natural and artificial nutrient media and has marked antigenic properties.. Known strains of Actinobaculum (Corynebacterium, Eubacterium, Actinomyces) suis allocated M. A. Soltys, ...
Liver abscesses containing hypervirulent Klebsiella pneumoniae have emerged during the past 2 decades, originally in Southeast Asia and then worldwide. We hypothesized that hypervirulent K. pneumoniae might also be emerging in France. In a retrospect ...
Functional Study 3: Elucidate the role and function of the Mycobacterium tuberculosis virulence-associated protein Rv0577.Project lead: Garry Buchko, PNNLProject collaborators: Chang Kim, Ph.D., Los Alamos National LaboratoryStatus: Project completed Link to original prooposal
Susceptibility to R. equi pneumonia in foals is exclusive to the first 2-3 months of life. This bacterium causes severe pneumonia, enteritis and occasionally joint infection, with significant economic losses to the horse industry, and critical concerns about equine health and well-being. R. equi is prevalent in the horse environment (soil), and foals are exposed to it immediately after birth. Importantly, R. equi survives and replicates inside immune cells (macrophages); therefore, this bacterium has developed a mechanism to escape the immune system and cause disease. Our hypothesis is that phagocytes of the susceptible foal have impaired killing activity against R. equi because of inadequate signaling from the airway epithelial cells. Our previous studies funded by the Harry M. Zweig Memorial Fund for Equine Research revealed that specialized phagocytes present an age-dependent limitation in their activation, which may be a consequence of inadequate stimulus. This age-dependent development of ...
3P-036 Rhodococcus属菌のフタル酸モノエステル加水分解酵素に重要なアルギニン残基(酵素学,酵素工学,一般講演)3P-036 Rhodococcus属菌のフタル酸モノエステル加水分解酵素に重要なアルギニン残基(酵素学,酵素工学,一般講演)AN10549378 ...
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Rhodococcus equi is a significant cause of pneumonia in foals and immunocompromised humans. Antimicrobial resistance among R. equi isolates has developed as a consequence of inappropriate stewardship and bacterial evolution, leading to an increased rate of treatment failures that typically result in foal fatality. In the current study, we evaluated the efficacy of antimicrobial silver nanoparticle (AgNP) complexes in controlling R. equi growth. Previous studies characterizing AgNP-induced antibacterial effects in other Gram-positive pathogens led us to hypothesize that silver nanoparticle antimicrobials impact R. equi viability and intracellular replication. We therefore investigated the effect of silver nanoparticle complexes on R. equi growth; assessed whether silver nanoparticle complexes prevent intracellular replication of R. equi; and evaluated the safety of silver nanoparticles in host cells. The results presented here demonstrate that silver nanoparticle complexes exhibit bactericidal activity
We investigated the effects of a chronic, progressive infection with Renibacterium salmoninarum (Rs), the causative agent of bacterial kidney disease (BKD), on selected aspects of smoltification in yearling juvenile spring chinook salmon (Oncorhynchus tshawytscha). After experimentally infecting fish with Rs using an immersion challenge, we sampled them every two weeks to monitor changes in gill Na+, K+-ATPase (ATPase), cortisol, infection level, mortality, growth, and other stress-related physiological factors during the normal time of parr-smolt transformation in fresh water (i.e., from winter to spring). A progressively worsening infection with Rs did not alter the normal changes in gill ATPase and condition factor associated with smoltification in juvenile chinook salmon. The infection did, however, lead to elevated levels of plasma cortisol and lactate and depressed levels of plasma glucose, indicating that the disease is stressful during the later stages. A dramatic proliferation of BKD was
Maulén, N. P., Morales, P. J., Aruti, D., Figueroa, J. E., Concha, M. I., Krauskopf, M. and León, G. (1996), Identification of a Renibacterium salmoninarum DNA fragment associated with bacterial internalization into CHSE-cultured cells. FEMS Microbiology Letters, 135: 37-43. doi: 10.1111/j.1574-6968.1996.tb07963.x ...
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Macrolide and rifampin resistance developed on a horse breeding farm after widespread use was instituted for treatment of subclinical pulmonary lesions in foals. Resistance occurred in 6 (24%) of 25 pretreatment and 8 (62%) of 13 (62%) posttreatment isolates from affected foals. Drug-resistant isolates formed 2 distinct genotypic clusters.
Fig. S1. Neighbour-joining unrooted trees of (A) DNA polymerase (E3 gp154) and (B) prohead protease (E3 gp77). Numbers in nodes are the percentage bootstrap values for 1000 replicates; values under 50% are not represented. Reference bacteriophages for accepted genera according to ICTV and NCBI taxonomy are indicated by asterisks. E3 proteins are indicated by arrows. The scale shows the number of amino acid substitutions per site. The topology of the phylogenetic trees (including the TerL tree; see Fig. ) reproduced the branching pattern of phage phylogenies based on whole genomes (Rohwer and Edwards, 2002; Glazko et al., 2007), and most well-supported clades grouped phages classified within an established genus.. Fig. S2. Alignment of the head morphogenesis module of R. equi phage E3, enterobacteriophage HK97 and mycobacteriophages Bxz1 and Myrna. Pairwise sequence similarity between adjacent genomes is indicated by shading. HP, hypothetical protein; PAP, protease-associated protein; ThyX, ...
ID BX251410; SV 1; linear; genomic DNA; STD; PRO; 324050 BP. XX AC BX251410; XX DT 17-FEB-2003 (Rel. 74, Created) DT 06-FEB-2015 (Rel. 123, Last updated, Version 4) XX DE Tropheryma whipplei TW08/27, complete genome; segment 1/3 XX KW complete genome. XX OS Tropheryma whipplei TW08/27 OC Bacteria; Actinobacteria; Micrococcales; Tropheryma. XX RN [1] RP 1-324050 RX DOI; 10.1016/S0140-6736(03)12597-4. RX PUBMED; 12606174. RA Bentley S.D., Maiwald M., Murphy L.D., Pallen M.J., Yeats C.A., Dover L., RA Norbertczak H.T., Besra G.S., Quail M.A., Harris D.E., von Herbay A., RA Goble A., Rutter S., Squares R., Squares S., Barrell B.G., Parkhill J., RA Relman D.A.; RT Sequencing and analysis of the genome of the Whipples disease bacterium RT Tropheryma whipplei; RL Lancet 361(9358):637-644(2003). XX RN [2] RP 1-324050 RA Bentley S.D.; RT ; RL Submitted (10-FEB-2003) to the INSDC. RL Submitted on behalf of the Pathogen Sequencing Unit, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, ...
Neonatal sepsis due to Rhodococcus equi in two preterm infants. Takçı, Şahin; Bildik, Hacer Neslihan; Yurdakök, Murat; Kara, Ateş // Turkish Journal of Pediatrics;Mar/Apr2013, Vol. 55 Issue 2, p229 We present two cases of Rhodococcus equi bacteremia as a cause of sepsis in premature infants who had increasing respiratory distress with multiple episodes of apnea. When we investigated these infants for apnea etiology, blood cultures were taken, and R. equi was confirmed based on the colony... ...
Statutory controls restrict the movement of live fish to and from the affected farm. Harvesting of clinically unaffected fish for human consumption is permissible but dead fish displaying clinical signs of disease should be disposed of by an approved method in accordance with the appropriate Animal By-Products Regulations. Under certain circumstances permission may be granted to move live fish from an affected farm to another farm subject to BKD controls if such a movement comprises part of a managed clearance and eradication programme and it poses no risk of further transmission of disease. Statutory controls are revoked when BKD is deemed to have been eradicated from the infected site. Eradication can be achieved by depopulating, cleaning and disinfecting an infected farm. Alternatively, eradication can also be achieved through a programme of progressive cleaning and disinfection along with careful management of infected stocks. This involves restocking with fish from a disease-free source and ...
The most common signs and symptoms of Whipples disease include:. The following signs and symptoms dont occur as frequently but can indicate that the condition is getting worse:. Infection with the T. whipplei bacteria is the one and only known cause of Whipples. The bacteria will lead to the development of internal sores and cause bodily tissues to thicken.. The villi are finger-like tissues that absorb nutrients in the small intestine. When the villi begin to thicken, their natural shape begins to change. This damages the villi and prevents them from effectively absorbing nutrients. This leads to many of the symptoms of Whipples disease.. A diagnosis of Whipples disease is complicated, especially because symptoms are similar to other more common conditions that range from celiac disease to neurological disorders. Your doctor will try to rule out these other conditions before diagnosing you with Whipples disease.. ...
Administration, Amino Acid Substitutions, Ciprofloxacin, Concentration, DNA, DNA Gyrase, Humans, Infection, Oral Administration, Rhodococcus, Rhodococcus Equi, Serum, Strains
Global Whipples Disease Market was around USD 206.2 million in 2016 and is expected to reach USD 255.3 million by 2023 at a projected CAGR of 3.1%,Whipples disease market by diagnosis,by treatment,by end use | Whipples Disease Industry
Estimating actual and ideal bodyweight of adult horses. New calculations more accurately estimate horse bodyweight without a livestock scale.
A typical case of Whipples disease is reported, substantiated by histopathologic study. Treatment with steroids has been used with good results. A prolonged clinical remission has occurred, although...
There are two groups of horses that are assessed and therefore valued to a large extent on their conformation and presentation-the halter horse and the sales weanling or yearling. Fat is a pretty color is an age-old adage, and some sales and halter horses are simply overfed, becoming too fat. In the modern sales and show arena, being fat is simply not enough. To be successful in preparing sales horses and halter horses, the fitter must be able to differentiate fat from fit.
ts very exciting to have the opportunity to school a young horse and see the progress through many hours of training, time and effort. However, all too often riders and trainers get carried away too quickly, and we subject the young horse to injury - not intentionally, but it can happen nonetheless. We explore the…
An im paired production of interleukin (IL)-12 and T cell interferon-γ (IFN-γ) of in vitro stimulated monocytes has been discussed as a pathogenic factor in Whi p ples disease (WD). It is unclear whe
விப்பிள் நோய் (Whipples disease) என்பது துரோபெரைமா விப்ளெய் எனும் பாக்டீரியாவினால் ஏற்படும் உடற்தொகுதி நோயாகும். சோர்ச் ஒய்ட் விப்பிள் 1907 இல் இதனை முதன்முதலில் கண்டறிந்தபோது இது சிறுகுடலில் உணவு அகத்துறிஞ்சாமையை ஏற்படுத்தும் இரையகக் குடலியநோய் என்று கருதினர். எனினும், மூட்டுக்கள், மைய நரம்புத் தொகுதி, குருதிச் சுற்றோட்டத் தொகுதி, நுரையீரல் தொகுதி போன்ற வேறு ஒருங்கியங்களையும் ...
All breeders hope to produce healthy, well-grown foals that continue to grow and thrive. It is known that larger mares tend to deliver larger foals and that a mares first foal may be somewhat smaller than her later foals.
Analysis of transcriptional responses of BMDMs to T. whipplei.BMDMs were stimulated with T. whipplei (50 bacteria/cell) for six hours and host responses were an
Acrorenoocular syndrome Acrospiroma ACTH deficiency ACTH resistance Actinic keratosis Actinomycetales causes anal infection ... propionic Acitretine antenatal infection Ackerman syndrome Acne rosacea Acne vulgaris; often called acne Acoustic neuroma ... syndrome Albright-Turner-Morgani syndrome Albright's hereditary osteodystrophy Albright's syndrome Alcohol antenatal infection ... neonatorum Aspiration pneumonia Asplenia Astasia-abasia Astasis Asthenia Asthma Astigmatism Astrocytoma Astrovirus infection ...
New Microbes and New Infections. 14: 8-9. doi:10.1016/j.nmni.2016.07.011. "Flaviflexus massiliensis". www.uniprot.org. v t e ( ... Articles with short description, Short description matches Wikidata, Articles with 'species' microformats, Actinomycetales, ...
"Varibaculum cambriense Infections in Hong Kong, China, 2006". Emerging Infectious Diseases. 15 (7): 1137-1139. doi:10.3201/ ... Actinomycetales, Bacteria genera, All stub articles, Actinomycetota stubs). ...
It has been known to cause head and neck infections, pharyngitis, and sinusitis (Arcanobacterium haemolyticum infections). It ... Actinomycetales, Bacteria described in 1946). ... A. haemolyticum infection is most common in 15- to 25-year-old ... The use of parenteral antimicrobial drugs must be limited to serious infections. Arcanobacterium haemolyticum infection Volante ... Symptoms look like those of β-hemolytic streptococci or viral infection. A rash of the chest and of the abdomen, neck, or ...
... vibrio infections MeSH C01.252.400.959.347 - cholera MeSH C01.252.410.040 - actinomycetales infections MeSH C01.252.410.040.137 ... bacteroides infections MeSH C01.252.400.126 - bartonellaceae infections MeSH C01.252.400.126.100 - bartonella infections MeSH ... moraxellaceae infections MeSH C01.252.400.560.022 - acinetobacter infections MeSH C01.252.400.610 - mycoplasmatales infections ... salmonella infections, animal MeSH C01.252.400.310.821.873 - typhoid fever MeSH C01.252.400.310.850 - serratia infections MeSH ...
"Varibaculum cambriense Infections in Hong Kong, China, 2006". Emerging Infectious Diseases. 15 (7): 1137-1139. doi:10.3201/ ... Actinomycetales, Bacteria described in 2003, All stub articles, Actinomycetota stubs). ...
Gomez-Garces, J. L.; Burillo, A.; Gil, Y.; Saez-Nieto, J. A. (2010). "Soft Tissue Infections Caused by Actinomyces neuii, a ... Actinomycetales, Gram-positive bacteria, Bacteria described in 1995, All stub articles, Actinomycetota stubs). ...
Actinomycetales, Bacteria described in 2002, All stub articles, Actinomycetota stubs). ... "Phenotypic and Genotypic Characterization of Arcanobacterium haemolyticum Isolates from Infections of Horses". Journal of ...
2003). "Characterization and clinical manifestations of Arcanobacterium phocae infections in marine mammals stranded along the ... Actinomycetales, Bacteria described in 1997, All stub articles, Actinomycetota stubs). ...
New Microbes and New Infections. 7: 21-22. doi:10.1016/j.nmni.2015.05.001. Silva, W. A.; Pinheiro, A. M.; Jahns, B.; Bögli- ... Actinomycetales, Bacteria described in 1997, All stub articles, Actinomycetota stubs). ... Stuber, K.; Droz, S.; Zimmerli, S. (June 2011). "Breast abscess due to Actinomyces europaeus". Infection. 39 (3): 255-258. doi: ...
Actinomycetales) with one new combination and six new species of the genus Frankia Brunchorst 1886, 174". Int J Syst Evol ... The first symptom of infection by Frankia alni is a branching and curling of the root hairs of the alder as the bacterium moves ... "Frankia infection process". Web.uconn.edu. Retrieved 2011-01-16. "Frankia nitrogen fixation". Web.uconn.edu. Retrieved 2011-01- ...
Infection is established first by a breach of the mucosal barrier during various procedures (dental, gastrointestinal), ... Actinomycetales, Gram-positive bacteria, Bacteria described in 1898). ... Wade, William G.; Könönen, Eija (2015-04-01). "Actinomyces and Related Organisms in Human Infections". Clinical Microbiology ... Valour, Florent (5 July 2014). "Actinomycosis: etiology, clinical features, diagnosis, treatment, and management". Infection ...
Actinomycetales, Gram-positive bacteria, Bacteria described in 2001, All stub articles, Actinomycetota stubs). ... detection of Propionibacterium propionicus and Actinomyces radicidentis in primary and persistent endodontic infections". Oral ...
It is often associated with vaginal infections. Spiegel, C. A.; Roberts, M. (1984). "Mobiluncus gen. nov., Mobiluncus curtisii ... Actinomycetales, Bacteria described in 1984, All stub articles, Actinomycetota stubs). ... Mayer, Jeanmarie; Hegewald, Susan; Sartor, Victor E.; Carroll, Karen (1994). "Extragenital infection due to Mobiluncus mulieris ...
258-261 M. F. Madelin "Virus infections of invertebrates" L.E. Hawker, A.H. Linton (Eds.), Micro-organisms: form, function and ... 251-256 M. F. Madelin, "Actinomycetales" L.E. Hawker, A.H. Linton (Eds.), Micro-organisms: form, function and environment, ... 233-271 M. F. Madelin, "Laboratory studies on the infection of Anopheles gambiae Giles by a species of Coelomomyces" World ... 473-480 M. F. Madelin, "Studies on the infection by Coelomomyces indicus of Anopheles gambiae" Journal of the Elisha Mitchell ...
... viscosus infection symptoms are indistinguishable from Actinomyces israelii infection symptoms or Actinomyces bovis infection ... Actinomycetales, Gram-positive bacteria). ... Infections are treatable with penicillin for three-week ... A. israelii and A. bovis infections usually cause actinomycotic infections, but sometimes and very rarely will the pathogen be ... Multiple-week antibiotic therapies have cured actinomycotic infections caused by A. viscosus in every recorded case. Therapies ...
Cattoir, Vincent (2012). "Actinobaculum schaalii: Review of an emerging uropathogen". Journal of Infection. 64 (3): 260-267. ... Actinomycetales, Bacteria described in 1997, All stub articles, Actinomycetota stubs). ... "Ten Cases of Actinobaculum schaalii Infection: Clinical Relevance, Bacterial Identification, and Antibiotic Susceptibility". ...
ISBN 978-0-531-09806-6. Wuerthele-Caspe, V (1955). "Neoplastic infections of man and animals". Journal of the American Medical ... attributing characteristics to Actinomycetales (the order Livingston believed P. cryptocides belonged to) shared by no other ... The microbe was classified under the order Actinomycetales. Livingston described Progenitor as an intermittently acid-fast ...
Infections of the mouth, face, and neck are the most commonly recognized infections; however, the thoracic region, abdomen, ... Actinomycetales, Bacterial vaginosis, Bacteria described in 1951, All stub articles, Actinomycetota stubs). ...
Infection leads to inflammation and the release of interleukin-6 (IL-6 ) which stimulates hepcidin expression. In humans, IL-6 ... Common Gram-positive species are those belonging to the Actinomycetales and species of the genera Bacillus, Arthrobacter and ... With bacterial vascular diseases, the infection is spread within the plants through the xylem. Once within the plant, the ... Lactoferrin is present in secretory fluids, such as sweat, tears and milk, thereby minimising bacterial infection. Ferritin is ...
Two Actinomycetales bacteria Streptomyces asiaticus and S. cangkringensis have been isolated from the rhizosphere soil ... "Initial infection of Falcataria moluccana leaves and Acacia mangium phyllodes by Uromycladium tepperianum fungi in a laboratory ...
To diagnose lumpy jaw, the fluids exuding from the bony lump or other abscesses are sampled or aspirated if the infection has ... Actinomycetales, Gram-positive bacteria, Bacteria described in 1877). ... The first is called the exogenous theory and was developed by Bostroem in 1891, when he suggested infection is caused by a ... The number and virulence of bacterial particles involved in the infection have been suggested to contribute to whether or not ...
Cell Biology and Infection, Developmental Biology, Genomes and Genetics, Immunology, Infection and Epidemiology, Microbiology, ... Having observed that most actinomycetales are saprophytes, that are able to survive outside of living organisms, with the help ... Yersin looked for the germ responsible for the infection specifically in these plague spots, tumors caused by the inflammation ... The discovery and use of sulfonamides in treating infections were another of its earlier breakthroughs. Some researchers ...
Some can cause disease in humans and other animals (for example, Arcanobacterium haemolyticum infections). As with various ... Actinomycetales). ...
Brakhage AA (December 2005). "Systemic fungal infections caused by Aspergillus species: epidemiology, infection process and ... Many Actinomycetales (Actinomycetota), a group with many filamentous bacteria, were also long believed to be fungi. Although ... Struck C (2006). "Infection strategies of plant parasitic fungi". In Cooke BM, Jones DG, Kaye B (eds.). The Epidemiology of ... Koeck, M.; Hardham, A.R.; Dodds; P.N. (2011). "The role of effectors of biotrophic and hemibiotrophic fungi in infection". ...
The bacterial order Actinomycetales, also share homologs of the 20S proteasome, whereas most bacteria possess heat shock genes ... The molecule ritonavir, marketed as Norvir, was developed as a protease inhibitor and used to target HIV infection. However, it ... the 11S may play a role in degradation of foreign peptides such as those produced after infection by a virus. The number and ... such as infection, heat shock, or oxidative damage - heat shock proteins that identify misfolded or unfolded proteins and ...
Clinical laboratories do culture and isolate them, but a negative result does not rule out infection, because it may be due ... Actinomycetales, Gram-positive bacteria, Bacteria genera). ... and refractory infection after a typical course of antibiotics ... As with other opportunistic infections, people with immunodeficiency are at higher risk. In all of the preceding traits and in ... Actinomycota are normally present in the gums, and are the most common cause of infection in dental procedures and oral ...
"First description of an Anaerobiospirillum succiniciproducens prosthetic joint infection". New Microbes and New Infections. 18 ... Pridham, T.G. (1970). "New names and new combinations in the order Actinomycetales Buchanan 1917" (PDF). Bulletin of the United ... It can be potentially lethal to humans, but infections are rare. † Archaeoacanthocircus angustiannulatus Kozur, Moix & Ozsvárt ...
Lan, R; Reeves, PR (2002). "Escherichia coli in disguise: molecular origins of Shigella". Microbes and Infection / Institut ... Actinomycetales, Streptomycetales, and Flexibacteriales. Walter Migula's system, which was the most widely accepted system of ... several orders such as Bacillales and Actinomycetales (now in the phylum Actinobacteria) Mollicutes (gram variable, e.g. ... classes Actinomycetales, Myxobacteriales, and Azotobacteriales) Algobacteriales (classes Siderobacteriales and Thiobacteriales ...
Results of search for su:{Actinomycetales infections} Refine your search. *. Availability. * Limit to currently available ...
Categories: Actinomycetales Infections Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Actinomycetales Infections. Gram-Positive Bacterial Infections. Bacterial Infections. Bacterial Infections and Mycoses. ... Infections. Respiratory Tract Infections. Lung Diseases. Respiratory Tract Diseases. Moxifloxacin. Rifampin. Isoniazid. ...
Bacteria in the order of Actinomycetales cause chronic infections. This order includes Mycobacteriaceae, Actinomycetaceae and ... Section 19: Infections. » Section 19, Chapter 1: Infections of the Spine. Section 19, Chapter 1: Infections of the Spine. ... Primary spinal infections are described as infections of the vertebrae that are not secondary to an operation. Such infections ... Postoperative surgical site infections may present as a superficial or deep infection. Superficial infections involve only the ...
... is the most common cause of infection-related death worldwide. In 1993, the World Health Organization (WHO) declared TB to be a ... Tubercle bacilli belong to the order Actinomycetales and family Mycobacteriaceae. Mycobacterium tuberculosis is the most common ... In fact, infection with human immunodeficiency virus (HIV) is one of the most significant risk factors for TB infection. Case ... Primary infection of the respiratory tract occurs as a result of inhalation of these aerosols. The risk of infection is ...
Acrorenoocular syndrome Acrospiroma ACTH deficiency ACTH resistance Actinic keratosis Actinomycetales causes anal infection ... propionic Acitretine antenatal infection Ackerman syndrome Acne rosacea Acne vulgaris; often called acne Acoustic neuroma ... syndrome Albright-Turner-Morgani syndrome Albrights hereditary osteodystrophy Albrights syndrome Alcohol antenatal infection ... neonatorum Aspiration pneumonia Asplenia Astasia-abasia Astasis Asthenia Asthma Astigmatism Astrocytoma Astrovirus infection ...
Infection caused by Actinomycetales (disorder). Code System Preferred Concept Name. Infection caused by Actinomycetales ( ... Infection caused by Actinomycetales (disorder) {721751007 , SNOMED-CT } Parent/Child (Relationship Type) Actinomycotic ... Infection caused by Mycobacteroides abscessus (disorder) {373029007 , SNOMED-CT } Infection caused by Rhodococcus hoagii ( ... Infection caused by Arcanobacterium pyogenes (disorder) {15246001 , SNOMED-CT } Infection caused by Corynebacterium (disorder ...
Actinomycetales. Copyright Restrictions:. None - This image is in the public domain and thus free of any copyright restrictions ...
Actinomycetales Infections * Animals * Horse Diseases * Horses * Immunoblotting * Incidence * Kentucky * Pneumonia, Bacterial * ...
Actinomycetales infections. Cholera. Dengue. Dengue fever. Diseases. Dysentery. Infectious diseases. Kala-azar. ...
Gram-Positive Bacterial Infections [C01.252.410]. *Actinomycetales Infections [C01.252.410.040]. *Mycobacterium Infections [ ... "Mycobacterium Infections" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Disseminated nontuberculous mycobacterial infections in sickle cell anemia patients. J Pediatr Hematol Oncol. 2006 Oct; 28(10): ... This graph shows the total number of publications written about "Mycobacterium Infections" by people in this website by year, ...
Actinomycetales Infections. *Antibodies, Bacterial. *Bacterial Vaccines. *Polysaccharides, Bacterial. *Pseudomonas aeruginosa. ... Disseminated Rhodococcus equi infection in a kidney transplant patient without initial pulmonary involvement. Diagn Microbiol ... It causes bronchopneumonia in foals and can be responsible for infection in humans compromised by immunosuppressive drug ... Is Associated with Protecting Newborn Foals against Intrabronchial Infection with Rhodococcus equi. Microbiol Spectr. 2021 09 ...
Actinomycosis is a subacute-to-chronic bacterial infection caused by filamentous, gram-positive, non-acid-fast, anaerobic-to- ... Actinomycosis in HIV infection: a review of a rare complication. Int J STD AIDS. 2000 Jun. 11(6):349-55. [QxMD MEDLINE Link]. ... They belong to the order of Actinomycetales, family Actinomycetaceae, genus Actinomyces. The continued development of advanced ... 5] Actinomyces and Actinomyces-like organisms emerging as potential causes of infection at various body sites. [6] Members of ...
... is the most common cause of infection-related death worldwide. In 1993, the World Health Organization (WHO) declared TB to be a ... Tubercle bacilli belong to the order Actinomycetales and family Mycobacteriaceae. Mycobacterium tuberculosis is the most common ... In fact, infection with human immunodeficiency virus (HIV) is one of the most significant risk factors for TB infection. Case ... Primary infection of the respiratory tract occurs as a result of inhalation of these aerosols. The risk of infection is ...
Actinomycotic infections Includes: actinomycotic mycetoma infection by Actinomycetales such as species of Actinomyces, ... infection Rat tapeworm (infection) 123.8 Other Diplogonoporus (grandis) infection Dipylidium (caninum) infection Dog tapeworm ( ... infection) Threadworm infection 127.5 Capillariasis Infection by Capillaria philippinensis Excludes: infection by Capillaria ... infection) Human T-cell lymphotropic virus-III (disease) (illness) (infection) HTLV-III (disease) (illness) (infection) HTLV- ...
Bacterial Infections [C01.252]. *Gram-Positive Bacterial Infections [C01.252.410]. *Actinomycetales Infections [C01.252.410.040 ... Anti-TNF-a agents Modulate SARS-CoV-2 Receptors and Increase the Risk of Infection Through Notch-1 Signaling. Front Immunol. ...
Actinomycetales Infections Animals Asymptomatic Infections Breeding Dispatch Drug Resistance, Multiple, Bacterial Genes, ...
... is an infection caused by a soil-borne aerobic filamentous bacterium in the genus Nocardia and the order Actinomycetales. ... Isolated infection of the sphenoid sinus is uncommon. It usually occurs in conjunction with infection of the other paranasal ... Penicillium marneffei is a dimorphic fungus that can cause infection in immunocompromised hosts. Reports on infection with this ... Disseminated Penicillium marneffei Infection: A Report of Five Cases in Singapore. A Kurup, Y S Leo, A L Tan, S Y Wong ...
Infections of the oral and cervicofacial regions are the most commonly recognized infections; however, the thoracic region, ... non-acid-fast anaerobic or microaerophilic bacilli of the genus Actinomyces and the order Actinomycetales cause actinomycosis. ... Pulmonary infections usually arise after aspiration of oropharyngeal or GI secretions. GI infection frequently follows loss of ... Funke G, von Graevenitz A. Infections due to Actinomyces neuii (former "CDC coryneform group 1" bacteria). Infection. 1995 Mar- ...
Russian Journal of Infection and Immunity , Peer-rewieved medical journal ... of cases detecting acid-fast microbial members from the order Actinomycetales while developing human bacterial infections has ... The frequency of infection has currently become a threat without tending to decline. Undoubtedly, Staphylococcus aureus is a ... Urinary tract infection (UTI) is one of the urgent problems in pediatric nephrology and pediatrics. Despite numerous works ...
C01.252 Bacterial Infections .. C01.252.410 Gram-Positive Bacterial Infections .. C01.252.410.040 Actinomycetales Infections . ... Mycobacterium tuberculosis Infection .. Infection, Mycobacterium tuberculosis .. Infections, Mycobacterium tuberculosis .. Koch ... C01.252.410.040.552 Mycobacterium Infections .. C01.252.410.040.552.846 Tuberculosis .. C01.252.410.040.552.846.719 ...
Bacterial Infections [C01.150.252] * Gram-Positive Bacterial Infections [C01.150.252.410] * Actinomycetales Infections [C01.150 ... Infection of the lymph nodes by tuberculosis. Tuberculous infection of the cervical lymph nodes is scrofula.. Entry Term(s). ... Infection of the lymph nodes by tuberculosis. Tuberculous infection of the cervical lymph nodes is scrofula.. Terms. ... Mycobacterium Infections [C01.150.252.410.040.552] * Tuberculosis [C01.150.252.410.040.552.846] * Latent Tuberculosis [C01.150. ...
Actinomycetales Infections * Addiction Medicine * Adenoma * Administration, Intravenous * Adolescent * Adolescent Medicine * ...
Bacterial Infections [C01.252]. *Gram-Positive Bacterial Infections [C01.252.410]. *Actinomycetales Infections [C01.252.410.040 ...
Bacterial Infections [C01.252]. *Gram-Positive Bacterial Infections [C01.252.410]. *Actinomycetales Infections [C01.252.410.040 ...
This organism has been isolated from cases of systemic infection, usually in association with other diseases.. ... Host Lineage: Tsukamurella paurometabola; Tsukamurella; Tsukamurellaceae; Actinomycetales; Actinobacteria; Bacteria. General ... Information: Isolation: Cases of systemic infection, usually in association with other diseases; Temp: Mesophile; Habitat: ...
  • Infections with bacteria of the genus MYCOBACTERIUM. (childrensmercy.org)
  • Gram-positive, pleomorphic non-spore-forming, non-acid-fast anaerobic or microaerophilic bacilli of the genus Actinomyces and the order Actinomycetales cause actinomycosis. (medscape.com)
  • A genus of obligate aerobic bacteria, family Mycobacteriaceae, order Actinomycetales. (thefreedictionary.com)
  • General Information: This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. (up.ac.za)
  • Mycobacterium Infections" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
  • This graph shows the total number of publications written about "Mycobacterium Infections" by people in this website by year, and whether "Mycobacterium Infections" was a major or minor topic of these publications. (childrensmercy.org)
  • Below are the most recent publications written about "Mycobacterium Infections" by people in Profiles. (childrensmercy.org)
  • A general term for MYCOBACTERIUM infections of any part of the UROGENITAL SYSTEM in either the male or the female. (nih.gov)
  • This category will also be used in primary coding to classify bacterial infections of unspecified nature or site. (cdc.gov)
  • Tubercle bacilli belong to the order Actinomycetales and family Mycobacteriaceae. (medscape.com)
  • Tuberculosis (TB) is the most common cause of infection-related death worldwide. (medscape.com)
  • For patient education information, see the Infections Center and Tuberculosis . (medscape.com)
  • See Medscape Drugs & Diseases articles Tuberculosis , Miliary Tuberculosis , Primary Tuberculosis Imaging , Pediatric HIV Infection , and HIV Disease for more information on these topics. (medscape.com)
  • Case rates for persons who are dually infected with HIV and M tuberculosis exceed the lifetime risk of persons with TB infection who are not infected with HIV. (medscape.com)
  • Infection of the lymph nodes by tuberculosis. (nih.gov)
  • Infection of the LIVER with species of MYCOBACTERIUM , most often MYCOBACTERIUM TUBERCULOSIS . (nih.gov)
  • nontuberculous mycobacteria mycobacteria other than M. tuberculosis or M. bovis, consisting of nonpathogens and pathogens causing opportunistic infections in immunocompromised patients and infections in otherwise normal individuals. (thefreedictionary.com)
  • While the majority of nocardial infections have been attributed to Nocardia asteroides , other pathogenic Nocardia species that have been described include Nocardia brasiliensis, Nocardia otitidiscaviarum , and Nocardia transvalensis . (pharmamicroresources.com)
  • Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. (up.ac.za)
  • Bt species are believed to be non-infectious and have only on rare occasions been associated with opportunistic infections in humans. (cyp17-signal.com)
  • Regardless of the source of the infection, an infection of the spine should be quickly diagnosed in order to prevent structural instability or neurologic compromise. (wheelessonline.com)
  • Among adults, persistent SARS-CoV-2 RNA was associated with an increased abundance of an unclassified member of the Actinomycetales order. (bvsalud.org)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
  • This organism has been isolated from cases of systemic infection, usually in association with other diseases. (up.ac.za)
  • Human infections can be persistent and may lead to systemic infection and arthritis. (up.ac.za)
  • Infection usually is caused by bacterial organisms, but can also be due to viral or fungal organisms. (wheelessonline.com)
  • Relevance of investigating the complement system components for diverse populations is tremendous, taking into consideration accumulated evidence regarding an important role of the lectin pathway in viral infections. (iimmun.ru)
  • Nasopharyngeal swabs were used to determine SARS-CoV-2 infection status, characterize the nasopharyngeal microbiota and determine common respiratory DNA/RNA viral co-infections. (bvsalud.org)
  • Kingdom case of bacteremia with Streptomyces acquired influenza B infection imme- thermovulgaris . (cdc.gov)
  • 5,14 That prevalence of this infection increases with age is possibly due to a number of factors: the increasing age of the population, increasing number of patients on renal replacement therapy, increasing number of patients with immunosuppressive medications and increasing rates of bacteremia due to intravascular devices and other forms of instrumentation. (wheelessonline.com)
  • The most common sources are urinary tract infections and the transient bacteremia caused by genitourinary procedures. (wheelessonline.com)
  • Although the aerobic actinomycetes are infrequently encountered in clinical practice, they are important potential causes of serious human and animal infections. (pharmamicroresources.com)
  • Many cause respiratory tract infections during the abdominal pain in the right lower pilgrims from throughout the world, pilgrimage (hajj) season in Makkah, Saudi quadrant and feculent vomitus. (cdc.gov)
  • M. ho´minis is a common inhabitant of the vagina and cervix and causes infections of the male and female reproductive tracts, as well as respiratory disease and pharyngitis. (thefreedictionary.com)
  • Disseminated nontuberculous mycobacterial infections in sickle cell anemia patients. (childrensmercy.org)
  • Spinal infections involve pyogenic or granulomatous infections of the vertebral column, intervertebral discs, the dural sac or the epidural space. (wheelessonline.com)
  • Gram-positive organisms such as Staphylococcus aureus and Streptococcus species are the most commonly isolated organisms in patients with pyogenic vertebral infections. (wheelessonline.com)
  • [ 5 ] Actinomyces and Actinomyces -like organisms emerging as potential causes of infection at various body sites. (medscape.com)
  • abstract = "Infection caused by methicillin‐resistant Staphylococcus aureus (MRSA) is an increasing societal problem. (dtu.dk)
  • Tuberculous infection of the cervical lymph nodes is scrofula. (nih.gov)
  • M. intracellula´re occasionally causes chronic pulmonary disease in adults and lymph node infection in children. (thefreedictionary.com)
  • Actinomyces radicidentis , a recently described species, has been isolated with polymerase chain reaction from patients with endodontic infections. (medscape.com)
  • Other bacterial species that often are copathogens to Actinomyces species may aid spread of infection by inhibiting host defenses and reducing local oxygen tension. (medscape.com)
  • Several of species are associated with infections in immunocompromised people, especially those with AIDS. (thefreedictionary.com)
  • other species being representatives of several human and other animal microbiotae, and some of them can act as opportunistic pathogens for animals including humans being usually responsible for polymicrobial infections and more rarely for monomicrobial severe infections like osteoarticular infections or endocarditis. (cfsremission.com)
  • Also, contacts of persons with sputum-positive smears have an increased prevalence of infection as opposed to contacts of those with sputum-negative smears. (medscape.com)
  • Cryptococcosis is a well-recognised infection in immunocompromised patients, although its prevalence varies with the type of immune defect. (annals.edu.sg)
  • Causes two types of food poisoning, the emetic and diarrheal syndromes, and a variety of local and systemic infections. (metapathogen.com)
  • Once the organism is established locally, it spreads to surrounding tissues in a progressive manner, leading to a chronic, indurated, suppurative infection often with draining sinuses and fibrosis. (medscape.com)
  • A chronic communicable infection which is a principal or polar form of LEPROSY . (liu.edu)
  • When pil- had influenza B infection. (cdc.gov)
  • Invasive infections tive effect of the influenza vaccine. (cdc.gov)
  • Pulmonary infections usually arise after aspiration of oropharyngeal or GI secretions. (medscape.com)
  • These converters are frequently excessive for veins of that mouth and semantically Given under structures and uses infection disorder. (bluescompanion.de)
  • Urinary tract infection (cystitis) and renal pelvic infection (pyelonephritis) mainly affect sows. (vetbact.org)
  • Sepsis is a condition with life-threatening organ dysfunction, resulting from abnormal responses of the host to various infections.1 The underlying pathogenic mechanisms include an. (annals.edu.sg)
  • The systematic monitoring of ethical contents and events related to COVID-19 pandemic, carried out over the last two years, serves to develop a multi-professional discussion on one of the most relevant platforms - Russian Journal Infection and Immunity. (iimmun.ru)
  • Osteomyelitis following hematogenous spread of infection is the major mechanism by which adults and children contract vertebral osteomyelitis. (wheelessonline.com)
  • The extent of this spreading is larger in pediatric spines due to their blood vessels extending into the intervertebral disc, permitting the direct spread of infection to the discs. (wheelessonline.com)
  • Such infections commonly originate from elsewhere in the body and spread to the spine and its musculoskeletal components. (wheelessonline.com)
  • Spinal infections can also develop postoperatively and most often develop secondary to direct inoculation of the wound. (wheelessonline.com)
  • Primary spinal infections are described as infections of the vertebrae that are not secondary to an operation. (wheelessonline.com)
  • Children with current SARS-CoV-2 infection presented higher bacterial richness and increased Fusobacterium, Streptococcus and Prevotella abundance than non-infected children. (bvsalud.org)
  • For patients with HIV infection, the risk of developing TB is 7-10% per year. (medscape.com)
  • Spine infections are rare infections that can involve the intervertebral disc space (discitis), the vertebral bones, the spinal canal or adjacent soft tissues. (wheelessonline.com)
  • Infection is followed by a 2-8 week incubation period resulting in suppuration (pus) and organized ulcerating granulomas (tumorous lesions), predominantly localized in lymphatic and tendon sheaths, and cooler body tissues in the extremities. (up.ac.za)
  • The objective of this study was to characterize the nasopharyngeal microbiota of children and adults and its relation to SARS-CoV-2 infection and COVID-19 severity during the pandemic lockdown in Spain. (bvsalud.org)
  • Three major routes of spread are: (1) hematogenous spread from a distant infection, (2) direct inoculation from trauma, (3) direct inoculation following invasive spinal diagnostic procedures and from spinal surgery. (wheelessonline.com)
  • Infection spreads into vertebral bodies by first seeding underneath vertebral end plates, which is followed by disc and nearby vertebrae involvement. (wheelessonline.com)
  • Risk factors for infections of the spine involve conditions that weaken the patient's immune system, such conditions include diabetes mellitus, use of immunosuppressant medications, cancer, HIV/AIDS, malnutrition, history of an organ transplant and intravenous drug abuse. (wheelessonline.com)
  • In fact, infection with human immunodeficiency virus (HIV) is one of the most significant risk factors for TB infection. (medscape.com)
  • Anti-TNF-a agents Modulate SARS-CoV-2 Receptors and Increase the Risk of Infection Through Notch-1 Signaling. (harvard.edu)
  • Predisposing risk factors are specific to the type of infection encountered. (medscape.com)
  • The most common primary spinal infection is pyogenic vertebral osteomyelitis. (wheelessonline.com)
  • One specimen contained two spacer sequence types, raising the possibility of a double infection. (edu.au)
  • In certain instances, such as extremes of age or defects in cell-mediated immune (CMI) response (eg, human immunodeficiency virus [HIV] infection , malnutrition , administration of chemotherapy, prolonged steroid use), TB may develop. (medscape.com)