Actinomyces: A genus of gram-positive, rod-shaped bacteria whose organisms are nonmotile. Filaments that may be present in certain species are either straight or wavy and may have swollen or clubbed heads.Actinomyces viscosus: A species of ACTINOMYCES found in the oral cavity of man and hamsters. It has been isolated from actinomycotic lesions in swine, cats, and dogs and has been identified as a causative agent of animal diseases.Actinomycosis: Infections with bacteria of the genus ACTINOMYCES.Streptococcus sanguis: A gram-positive organism found in dental plaque, in blood, on heart valves in subacute endocarditis, and infrequently in saliva and throat specimens. L-forms are associated with recurrent aphthous stomatitis.Dental Plaque: A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.Hydroxyapatites: A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)Mouth: The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.Actinomycetaceae: A family of bacteria including numerous parasitic and pathogenic forms.Streptococcus mutans: A polysaccharide-producing species of STREPTOCOCCUS isolated from human dental plaque.Saliva: The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.Fimbriae, Bacterial: Thin, hairlike appendages, 1 to 20 microns in length and often occurring in large numbers, present on the cells of gram-negative bacteria, particularly Enterobacteriaceae and Neisseria. Unlike flagella, they do not possess motility, but being protein (pilin) in nature, they possess antigenic and hemagglutinating properties. They are of medical importance because some fimbriae mediate the attachment of bacteria to cells via adhesins (ADHESINS, BACTERIAL). Bacterial fimbriae refer to common pili, to be distinguished from the preferred use of "pili", which is confined to sex pili (PILI, SEX).Streptococcus: A genus of gram-positive, coccoid bacteria whose organisms occur in pairs or chains. No endospores are produced. Many species exist as commensals or parasites on man or animals with some being highly pathogenic. A few species are saprophytes and occur in the natural environment.Proline-Rich Protein Domains: Protein domains that are enriched in PROLINE. The cyclical nature of proline causes the peptide bonds it forms to have a limited degree of conformational mobility. Therefore the presence of multiple prolines in close proximity to each other can convey a distinct conformational arrangement to a peptide chain.Veillonella: A genus of gram-negative, anaerobic cocci parasitic in the mouth and in the intestinal and respiratory tracts of man and other animals.Salivary Proteins and Peptides: Proteins and peptides found in SALIVA and the SALIVARY GLANDS. Some salivary proteins such as ALPHA-AMYLASES are enzymes, but their composition varies in different individuals.Dental Pellicle: A thin protein film on the surface of DENTAL ENAMEL. It is widely believed to result from the selective adsorption of precursor proteins present in SALIVA onto tooth surfaces, and to reduce microbial adherence to the TEETH.DextranaseSalivary Proline-Rich Proteins: A family of proline-rich proteins that constitute the majority of the protein component of SALIVA. Salivary proline-rich proteins occur as acidic, basic and glycosylated basic proteins. They perform a variety of functions such as adhering to the acquired ENAMEL PELLICLE, acting as lubricants and precipitating TANNINS.Adhesiveness: A property of the surface of an object that makes it stick to another surface.Tooth: One of a set of bone-like structures in the mouth used for biting and chewing.Lactobacillus casei: A rod-shaped bacterium isolated from milk and cheese, dairy products and dairy environments, sour dough, cow dung, silage, and human mouth, human intestinal contents and stools, and the human vagina.Lactose: A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.Bacterial Adhesion: Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.Agglutination: The clumping together of suspended material resulting from the action of AGGLUTININS.Hemagglutination: The aggregation of ERYTHROCYTES by AGGLUTININS, including antibodies, lectins, and viral proteins (HEMAGGLUTINATION, VIRAL).Bacteroides: A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.Adsorption: The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.Durapatite: The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.Carbohydrates: The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES. Carbohydrates are composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n.Sucrose: A nonreducing disaccharide composed of GLUCOSE and FRUCTOSE linked via their anomeric carbons. It is obtained commercially from SUGARCANE, sugar beet (BETA VULGARIS), and other plants and used extensively as a food and a sweetener.Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Cell Wall: The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents.Antigens, Bacterial: Substances elaborated by bacteria that have antigenic activity.Lectins: Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.Polysaccharides, Bacterial: Polysaccharides found in bacteria and in capsules thereof.Corynebacterium pyogenes: A species of CORYNEBACTERIUM isolated from abscesses of warm-blooded animals.Neuraminidase: An enzyme that catalyzes the hydrolysis of alpha-2,3, alpha-2,6-, and alpha-2,8-glycosidic linkages (at a decreasing rate, respectively) of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid, and synthetic substrate. (From Enzyme Nomenclature, 1992)Streptococcus oralis: A species of gram-positive, coccoid bacteria that is numerous in the mouth and throat. It is a common cause of endocarditis and is also implicated in dental plaque formation.Hot Temperature: Presence of warmth or heat or a temperature notably higher than an accustomed norm.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
(1/19) Addition of antibacterial agents to MMA-TBB dentin bonding systems--influence on tensile bond strength and antibacterial effect.

To produce a bonding system which has both high bond strength and antibacterial properties, an antibacterial agent (vancomycin: VCM or metronidazol: MN) was added to the PMMA powder of 4-META/MMA-TBB resin (CB). The influence of the addition of an antibacterial agent on tensile bond strength to dentin and the antibacterial effect were investigated in this study. Forty-seven freshly extracted bovine first or second incisors were used to measure the tensile bond strength to dentin. The bond strengths to bovine dentin were not significantly decreased by addition of VCM (1%, 2%, 5%), or MN (1%) to CB (p < 0.05). The antibacterial effect of CB containing antibacterial agent on six strains of bacteria was investigated by the agar plate diffusion method, analyzing the appearance of the inhibition zone around a resin disk following anaerobic culturing. The resin disks containing VCM showed antibacterial effects on all of the strains examined; the widths of the inhibition zones were 4-15 mm. The resin disks containing MN showed antibacterial effects on three strains; the widths of the inhibition zones were 0-4 mm. It was thus possible to produce a bonding system with both antibacterial effect and high tensile bond strength by addition of VCM to PMMA powder.  (+info)

(2/19) Different type 1 fimbrial genes and tropisms of commensal and potentially pathogenic Actinomyces spp. with different salivary acidic proline-rich protein and statherin ligand specificities.

Actinomyces spp. exhibit type 1 fimbria-mediated adhesion to salivary acidic proline-rich proteins (PRPs) and statherin ligands. Actinomyces spp. with different animal and tissue origins belong to three major adhesion types as relates to ligand specificity and type 1 fimbria genes. (i) In preferential acidic-PRP binding, strains of Actinomyces naeslundii genospecies 1 and 2 from human and monkey mouths displayed at least three ligand specificities characterized by preferential acidic-PRP binding. Slot blot DNA hybridization showed seven highly conserved type 1 fimbria genes (orf1- to -6 and fimP) in genospecies 1 and 2 strains, except that orf5 and orf3 were divergent in genospecies 1. (ii) In preferential statherin binding, oral Actinomyces viscosus strains of rat and hamster origin (and strain 19246 from a human case of actinomycosis) bound statherin preferentially. DNA hybridization and characterization of the type 1 fimbria genes from strain 19246 revealed a homologous gene cluster of four open reading frames (orfA to -C and fimP). Bioinformatics suggested sortase (orfB, orf4, and part of orf5), prepilin peptidase (orfC and orf6), fimbria subunit (fimP), and usher- and autotransporter-like (orfA and orf1 to -3) functions. Those gene regions corresponding to orf3 and orf5 were divergent, those corresponding to orf2, orf1, and fimP were moderately conserved, and those corresponding to orf4 and orf6 were highly conserved. Restriction fragment length polymorphism analyses using a fimP probe separated human and monkey and rat and hamster strains into phylogenetically different groups. (iii) In statherin-specific binding, strains of A. naeslundii genospecies 1 from septic and other human infections displayed a low-avidity binding to statherin. Only the orf4 and orf6 gene regions were highly conserved. Finally, rat saliva devoid of statherin bound bacterial strains avidly irrespective of ligand specificity, and specific antisera detected either type 1, type 2, or both types of fimbria on the investigated Actinomyces strains.  (+info)

(3/19) Isolation and characterization of Actinomyces viscosus mutants defective in binding salivary proline-rich proteins.

Recent studies have provided evidence for human salivary proline-rich proteins (PRPs) serving as potential receptors in the acquired pellicle for Actinomyces viscosus type 1 fimbriae. We report here the isolation of mutants derived from A. viscosus T14V-J1 which are defective in binding to PRPs partially purified from parotid gland saliva. Mutagenesis with ethyl methanesulfonate preceded enrichment for cells nonreactive with PRPs by successive adsorptions with PRP-treated latex beads. Screening was accomplished by random selection of 250 isolated colonies from each of four enrichment cycles and reaction with PRP-treated latex beads in microtiter plates. Two mutants of independent origin were examined for adherence to hydroxyapatite treated with either PRPs, proline-rich glycoproteins, deglycosylated proline-rich glycoproteins, or whole saliva. Additional surface properties that were examined included agglutination with polyclonal antisera to type 1 and type 2 fimbriae, agglutination by a monoclonal antibody to type 1 fimbriae that inhibits adherence of the parent strain to saliva-treated hydroxyapatite, the ability to bind monoclonal antibody to the type 1 fimbrial subunit, and lactose-reversible coaggregation with Streptococcus sanguis 34. Both mutants exhibited reduced binding to hydroxyapatite treated with whole saliva or salivary protein preparations but were still capable of reaction with antiserum to type 1 and type 2 fimbriae. In addition, these mutants possessed the ability to bind monoclonal antibody to the type 1 fimbrial subunit in amounts comparable to the amount bound by the parent strain but were not agglutinated by the adherence-inhibiting monoclonal antibody. When considered with previously published data, these results suggest that an adhesive molecule is probably associated with type 1 fimbriae and allows for the interaction of A. viscosus with constituents in the salivary pellicle.  (+info)

(4/19) Effects of cecropin-XJ on growth and adherence of oral cariogenic bacteria in vitro.

BACKGROUND: Cecropin-XJ belongs to cecropin-B, which is the most potent antibacterial peptide found naturally. The aim of this study was to investigate the effects of cecropin-XJ on growth and adherence of oral cariogenic bacteria. METHODS: Four oral cariogenic bacteria (Streptococcus mutans, Lactobacillus acidophilus, Actinomyces viscosus and Actinomyces naeslundii) were chosen for this experiment. The minimal inhibitory concentrations (MICs) and reductive percent of bacterial growth were used to assay the antibacterial activity of cecropin-XJ. Mammalian cytotoxicity of cecropin-XJ was tested with human periodontal membrane fibroblasts by tetrazolium (MTT) colorimetric assay. The bacterial morphological changes induced by cecropin-XJ were examined on scanning electron microscope (SEM). The influence of cecropin-XJ on bacterial adhesion to saliva-coated hydroxyapatite (S-HA) was measured by scintillation counting. RESULTS: The MICs of cecropin-XJ for inhibition of the growth of four bacteria ranged from 4.0 to 42.8 micromol/L with the highest susceptible to A. naeslundii and the lowest susceptible to L. acidophilus. At pH 6.8, 5.5 and 8.2, 1/2 MIC of cecropin-XJ reduced the number of viable bacteria by 40.9%, 67.8% and 32.8% for S. mutans and by 28.1%, 57.2% and 37.9% for L. acidophilus. The activities against S. mutans and L. acidophilus increased at pH 5.5 compared with pH 6.8 (P < 0.01, respectively). In present of 50% saliva, 1/2 MIC of the peptide decreased the direct count of viable cells by 29.2% and 14.4% for S. mutans and L. acidophilus, respectively (P < 0.01 and P > 0.05, respectively), whereas almost no reduction counts were detected in the presence of 20% serum for both bacteria (P > 0.05, respectively). Mammalian cytotoxicity of cecropin-XJ from 1.0 to 100 micromol/L exhibited no cytotoxicity against human periodontal membrane fibroblasts (P > 0.05). Bacterial morphological changes induced by MIC of cecropin-XJ examined on SEM showed cell surface disruption. Furthermore, the ability of A. naeslundii adhesion to S-HA decreased significantly with MIC of cecropin-XJ for 10 and 20 minutes (P = 0.001 and 0.000, respectively), and S. mutans, A. viscosus to S-HA decreased significantly with MIC of cecropin-XJ for 20 minutes (P = 0.000, respectively). CONCLUSIONS: Cecropin-XJ exhibited bactericidal action against cariogenic pathogens, and the antibacterial activity enhanced in the acid environment. The results also demonstrate that cecropin-XJ prevents S. mutans and actinomyces adsorption to S-HA. These findings suggest that Cecropin-XJ may have potential to prevent caries.  (+info)

(5/19) Immunochemical and functional studies of Actinomyces viscosus T14V type 1 fimbriae with monoclonal and polyclonal antibodies directed against the fimbrial subunit.

Each of five monoclonal antibodies (mAbs) prepared against the type 1 fimbriae of Actinomyces viscosus T14V reacted with a 54 kDa cloned protein previously identified as a fimbrial subunit. This purified protein completely inhibited the reaction of a specific anti-type-1-fimbria rabbit antibody with A. viscosus whole cells. Maximum values for the number of antibody molecules bound per bacterial cell ranged from 7 x 10(3) to 1.2 x 10(4) for the different 125I-labelled mAbs and was approximately 7 x 10(4) for 125I-labelled rabbit IgG or Fab against either type 1 fimbriae or the 54 kDa cloned protein. Although the different mAbs, either individually or as a mixture, failed to inhibit the type-1-fimbria-mediated adherence of A. viscosus T14V to saliva-treated hydroxyapatite, each rabbit antibody gave 50% inhibition of adherence when approximately 5 x 10(4) molecules of IgG were bound per cell. However, binding of each corresponding rabbit Fab had no significant effect on bacterial attachment unless much higher concentrations were used. These findings suggest that antibodies directed solely against the 54 kDa fimbrial subunit do not react with the putative receptor binding sites of A. viscosus T14V type 1 fimbriae. Instead, inhibition of attachment by the polyclonal antibodies may depend on an indirect effect of antibody binding that prevents the fimbria-receptor interaction.  (+info)

(6/19) Tyrosine sulfation of statherin.

Tyrosylprotein sulfotransferase (TPST), responsible for the sulfation of a variety of secretory and membrane proteins, has been identified and characterized in submandibular salivary glands (William et al. Arch Biochem Biophys 1997; 338: 90-96). In the present study we demonstrate the sulfation of a salivary secretory protein, statherin, by the tyrosylprotein sulfotransferase present in human saliva. Optimum statherin sulfation was observed at pH 6.5 and at 20 mm MnCl(2). Increase in the level of total sulfation was observed with increasing statherin concentration. The K(m)value of tyrosylprotein sulfotransferase for statherin was 40 microM. Analysis of the sulfated statherin product on SDS-polyacrylamide gel electrophoresis followed by autoradiography revealed (35)S-labelling of a 5 kDa statherin. Further analysis of the sulfated statherin revealed the sulfation on tyrosyl residue. This study is the first report demonstrating tyrosine sulfation of a salivary secretory protein. The implications of this sulfation of statherin in hydroxyapatite binding and Actinomyces viscosus interactions are discussed.  (+info)

(7/19) Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens.

Antimicrobial peptides (AMPs) are naturally occurring, broad-spectrum antimicrobial agents that have recently been examined for their utility as therapeutic antibiotics. Unfortunately, they are expensive to produce and are often sensitive to protease digestion. To address this problem, we have examined the activity of a peptide mimetic whose design was based on the structure of magainin, exhibiting its amphiphilic structure. We demonstrate that this compound, meta-phenylene ethynylene (mPE), exhibits antimicrobial activity at nanomolar concentrations against a variety of bacterial and Candida species found in oral infections. Since Streptococcus mutans, an etiological agent of dental caries, colonizes the tooth surface and forms a biofilm, we quantified the activity of this compound against S. mutans growing under conditions that favor biofilm formation. Our results indicate that mPE can prevent the formation of a biofilm at nanomolar concentrations. Incubation with 5 nM mPE prevents further growth of the biofilm, and 100 nM mPE reduces viable bacteria in the biofilm by 3 logs. Structure-function analyses suggest that mPE inhibits the bioactivity of lipopolysaccharide and binds DNA at equimolar ratios, suggesting that it may act both as a membrane-active molecule, similar to magainin, and as an intracellular antibiotic, similar to other AMPs. We conclude that mPE and similar molecules display great potential for development as therapeutic antimicrobials.  (+info)

(8/19) Isolation of a neuraminidase gene from Actinomyces viscosus T14V.

A genomic library of Actinomyces viscosus T14V DNA in lambda gt11 was screened for expression of neuraminidase activities. Four recombinant clones were detected that gave blue fluorescence upon incubation with a fluorogenic substrate, 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid. Of these, two were identical, and all of the neuraminidase-positive clones shared a common 3.4-kbp DNA region. Expression of the enzyme activities in Escherichia coli carrying the cloned DNA was independent of the lacZ promoter of the vector. Maxicell analysis revealed that the 3.4-kbp DNA insert directed synthesis of a protein with an apparent molecular mass of 100,000 Da. The protein from cell extracts of E. coli clones migrated as a single band that stained for enzyme activity after electrophoresis in a nondissociating polyacrylamide gel. Moreover, human erythrocytes incubated previously with cell lysates from neuraminidase-positive E. coli were hemagglutinated by Actinomyces spp. The enzyme expressed by E. coli was active on substrates containing alpha-2,3 and alpha-2,6 ketosidic linked sialyl residues. Similar substrate specificities were obtained for both the extracellular and cell-associated neuraminidases from A. viscosus T14V. The 3.4-kbp insert hybridized to DNA fragments in a Southern blot containing A. viscosus T14V chromosomal DNA that had been digested with various restriction endonucleases. Data from hybridization studies show that A. viscosus T14V contains a single copy of the neuraminidase gene.  (+info)

*  Actinomyces viscosus
"Oral bacterium - Actinomyces viscosus". Dennis Kunkel Microscopy, Inc. Retrieved 19 December 2015. "Actinomyces viscosus. (n.d ... Actinomyces viscosus is a human and animal pathogen/pathobiont which colonises the mouths of 70% of adult humans. A. viscosus ... A. viscosus infection symptoms are indistinguishable from Actinomyces israelii infection symptoms or Actinomyces bovis ... "Actinomyces viscosus". Retrieved 19 December 2015. Mardis, JS; Many, WJ Jr (February 2001). "Endocarditis ...
*  Actinomyces georgiae
... naeslundii serotypes II and III and Actinomyces viscosus serotype II in A. naeslundii Genospecies 2". International Journal of ... Actinomyces georgiae is a species in the genus of Actinomyces. It is a part of the human periodontal flora. Johnson, J. L.; ... Actinomyces georgiae at the Encyclopedia of Life LPSN Type strain of Actinomyces georgiae at BacDive - the Bacterial Diversity ... nov., Actinomyces gerencseriae sp. nov., Designation of Two Genospecies of Actinomyces naeslundii, and Inclusion of A. ...
*  Human microbiota
A number of types of bacteria, such as Actinomyces viscosus and A. naeslundii, live in the mouth, where they are part of a ... Anaerobic bacteria in the oral cavity include: Actinomyces, Arachnia, Bacteroides, Bifidobacterium, Eubacterium, Fusobacterium ...
*  List of MeSH codes (B03)
Actinomyces MeSH B03.510. --- Actinomyces viscosus MeSH B03.510. --- Mobiluncus MeSH B03.510. ... Actinomyces MeSH B03.510.460.400.400. --- Actinomyces viscosus MeSH B03.510.460.400.400.049.049.589 --- ...
*  Actinomyces gerencseriae
... naes.undii serotypes II and III and Actinomyces viscosus serotype II and A. naeslundii Genospecies 2" (PDF). International ... Actinomyces gerencseriae is a species in the genus Actinomyces once known as Actinomyces israelii serovar II. A. gerencseriae ... Type strain of Actinomyces gerencseriae at BacDive - the Bacterial Diversity Metadatabase Type strain of Actinomyces ... Johnson, J L; Moore, Lillian H; Kaneko, Beverly; Moore, W E C (July 1990). "Actinomyces georgiae, Actinomyces ...
*  Sagittaria sagittifolia
None of these displayed activity against A. actinomycetemcomitans, while four of the others were active against A. viscosus and ... exhibited antibacterial activity against Streptococcus mutans and Actinomyces naeslundii while another (Sagittine E) was only ...
Actinomyces viscosus bacteria, SEM - Stock Image F012/4031 - Science Photo Library  Actinomyces viscosus bacteria, SEM - Stock Image F012/4031 - Science Photo Library
Coloured scanning electron micrograph (SEM) of strands of Actinomyces viscosus. Actinomyces viscosus is a filamentous soil ... Actinomyces viscosus bacteria. Coloured scanning electron micrograph (SEM) of strands of Actinomyces viscosus. Actinomyces ... Keywords: actinobacteria, actinomyces viscosus, actinomyces viscosus bacteria, bacteria, bacterial, bacteriology, bacterium, ... viscosus is a filamentous soil bacterium, classified in the Actinobacteria.. Release details: Model release not required. ...
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Zoocin A and lauricidin in combination selectively inhibit Streptococcus mutans in a biofilm model  Zoocin A and lauricidin in combination selectively inhibit Streptococcus mutans in a biofilm model
A triple-species biofilm model was developed where S. mutans, Streptococcus oralis and Actinomyces viscosus were grown on glass ... viscosus remained elevated. Zoocin A and lauricidin also reduced biofilm formation and maintained the pH above 7.0, while the ...
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Actinomycosis  Actinomycosis
... refers to the disease entity caused by any one of the organisms of the genus Actinomyces. These organisms are ... viscosus, A. naeslundii). ... Actinomyces is universally exquisitely sensitive to penicillin ...
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Oral bacterium, Actinomyces viscosus, SEM - Stock Image - C032/2172 - Science Photo Library  Oral bacterium, Actinomyces viscosus, SEM - Stock Image - C032/2172 - Science Photo Library
Actinomyces viscosus. Actinomyces viscosus is a Gram-positive, anaerobic, filamentous bacterium that is part of the human oral ... Coloured scanning electron micrograph (SEM) of Oral bacterium, Actinomyces viscosus. Actinomyces viscosus is a Gram-positive, ... Actinomyces sp. normally are soil or aquatic fungi feeding off decaying matter (saprophytes). They resemble fungi and form ...
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Actinomyces viscosus - Wikipedia  Actinomyces viscosus - Wikipedia
"Oral bacterium - Actinomyces viscosus". Dennis Kunkel Microscopy, Inc. Retrieved 19 December 2015. "Actinomyces viscosus. (n.d ... Actinomyces viscosus is a human and animal pathogen/pathobiont which colonises the mouths of 70% of adult humans. A. viscosus ... A. viscosus infection symptoms are indistinguishable from Actinomyces israelii infection symptoms or Actinomyces bovis ... "Actinomyces viscosus". Retrieved 19 December 2015. Mardis, JS; Many, WJ Jr (February 2001). "Endocarditis ...
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Actinomyces viscosus | Article about Actinomyces viscosus by The Free Dictionary  Actinomyces viscosus | Article about Actinomyces viscosus by The Free Dictionary
Find out information about Actinomyces viscosus. The type genus of the family Actinomycetaceae; anaerobic to facultatively ... includes human and animal pathogens Explanation of Actinomyces viscosus ... Actinomyces. (redirected from Actinomyces viscosus). Also found in: Dictionary, Thesaurus, Medical.. Related to Actinomyces ... Actinomyces viscosus , Article about Actinomyces viscosus by The Free Dictionary ...
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Construction and use of integration plasmids to generate site-specific mutations in the Actinomyces viscosus T14V chromosome. |...  Construction and use of integration plasmids to generate site-specific mutations in the Actinomyces viscosus T14V chromosome. |...
Construction and use of integration plasmids to generate site-specific mutations in the Actinomyces viscosus T14V chromosome.. ... Stable transformants of Actinomyces viscosus T14V carrying heterologous DNA were obtained with the aid of integration plasmids ... Construction and use of integration plasmids to generate site-specific mutations in the Actinomyces viscosus T14V chromosome. ... Construction and use of integration plasmids to generate site-specific mutations in the Actinomyces viscosus T14V chromosome. ...
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By Organization / Company Page 1  By Organization / Company Page 1
Actinomyces viscosus (Howell et al.) Georg et al. (ATCC® 15987™) ATCC® Number: 15987™ Deposited As Odontomyces viscosus Howell ...
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Molecules  | Free Full-Text | The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic...  Molecules | Free Full-Text | The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic...
Actinomyces odontolyticus. 0. 1. 0. 1. 0. 0. 1. 1. Actinomyces viscosus. 1. 0. 0. 1. 0. 0. 1. 1. ... The number of Actinomyces israelii and Actinomyces naeslundii isolates in the control group was significantly higher in the ... The presence of Actinomyces spp. together with Actinomyces israelii, Capnocytophaga spp., Fusobacterium spp., Bacteroides spp. ... In our own study, a microflora of similar composition was isolated from the study subjects, while the number of Actinomyces spp ...
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Actinomycosis Treatment & Management: Medical Care, Surgical Care, Consultations  Actinomycosis Treatment & Management: Medical Care, Surgical Care, Consultations
Scarano FJ, Ruddat MS, Robinson A. Actinomyces viscosus postoperative endophthalmitis. Diagn Microbiol Infect Dis. 1999 Jun. 34 ... Disseminated Actinomyces meyeri infection resembling lung cancer with brain metastases. Am J Med Sci. 2003 Sep. 326(3):152-5. [ ... Hall V. Actinomyces--gathering evidence of human colonization and infection. Anaerobe. 2008 Feb. 14(1):1-7. [Medline]. ... Actinomyces and related organisms in human infections. Clin Microbiol Rev. 2015 Apr. 28 (2):419-42. [Medline]. ...
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CN104721063A - Dentifrice composition containing zinc oxide and zinc citrate 
        - Google Patents  CN104721063A - Dentifrice composition containing zinc oxide and zinc citrate - Google Patents
Actinomyces viscosus, Lactobacillus casei (Zac (oAaciBttscasei), Streptococcus oralis ora / is), Fusobacterium nucleatum (/ ...
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US4957686A - Use of bacteriophages to inhibit dental caries 
        - Google Patents  US4957686A - Use of bacteriophages to inhibit dental caries - Google Patents
Oral compositions comprising actinomyces viscosus fimbriae EP0776163A1 (en) * 1994-09-09. 1997-06-04. University Of Maryland. ... Oral compositions comprising actinomyces viscosus fimbriae EP0776163A4 (en) * 1994-09-09. 1999-11-24. Univ Maryland. ... The S. mutans and other acid producing bacteria such as Lactobacillae and Actinomyces sp and various anaerobic bacteria can act ...
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Magiran | مجله دانشگاه علوم پزشکی اراک، سال بیست و دوم شماره 4 (مهر و آبان 1398)  Magiran | مجله دانشگاه علوم پزشکی اراک، سال بیست و دوم شماره 4 (مهر و آبان 1398)
In concentration of 0.1 g/mL of Satureja plant, Actinomyces viscosus, Streptococcus sanguinis, Enterococcus faecalis, and ... and Actinomyces viscosus. We also used the disk diffusion test and broth microdilution method to evaluate the antimicrobial ...
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Evolution of substrate specificity in a retained enzyme driven by gene loss | eLife  Evolution of substrate specificity in a retained enzyme driven by gene loss | eLife
Isolation of a bacteriophage for Actinomyces viscosus. * AL Delisle. * RK Nauman. * GE Minah ... of Actinomyces naeslundii and Actinomyces oris, previously named 'Actinomyces naeslundii genospecies 1 and 2' * T Do ... Molecular and genetic analyses of Actinomyces spp * MK Yeung. (1999) Critical Reviews in Oral Biology and Medicine 10:120-138. ... Therefore, PriA homologs from Actinomyces have poor catalytic efficiencies when compared with bona fide PriAs from its closely ...
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The Genus Wolinella | SpringerLink  The Genus Wolinella | SpringerLink
Isolation of Wolinella recta and Actinomyces viscosus from an actinomycotic chest wall mass. J. Clin. Microbiol. 20: 1187-1189. ...
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Proteomic indicators of oxidation and hydration state in colorectal cancer [PeerJ]  Proteomic indicators of oxidation and hydration state in colorectal cancer [PeerJ]
3, revealing a higher ZC than any of the mean microbial proteins except for Actinomyces viscosus and Bifidobacterium animalis, ...
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DNA Pathogen Frequencies  DNA Pathogen Frequencies
Actinomyces viscosus. Tannerella forsythia (aka Tannerella forsythensis). Aggregatibacter actinomycetemeomitans. See also ... Actinomyces species (numerous). eMedicine. PMC4297926. 18222714. 25788515. African sleeping sickness. Trypanosoma brucei ...
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Oxygen metabolism, oxidative stress and acid-base physiology of dental plaque biofilms | SpringerLink  Oxygen metabolism, oxidative stress and acid-base physiology of dental plaque biofilms | SpringerLink
Membrane ATPases and acid tolerance ofActinomyces viscosus andLactobacillus casei. Appl Environ Microbiol 53: 2124-2128.PubMed ... 1990 Tetrameric manganese superoxide dismutases from anaerobicActinomyces. Arch Biochem Biophys 280: 192-200.PubMedGoogle ...
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  • In the transformant strain designated A. viscosus MY50D, the inactivated fimP replaced the wild-type fimP via allelic replacement. (
  • In contrast, strain MY52S synthesized the structural subunit protein, as detected by immunostaining with anti-A. viscosus T14V type 1 fimbria antibodies. (
  • These plasmids contained a kanamycin resistance (Kmr) gene flanked by A. viscosus T14V genomic DNA, including parts of the type 1 structural fimbrial subunit gene (fimP) on one or both sides of the antibiotic marker. (
  • Integration of this plasmid into the A. viscosus T14V genome affected the expression and function of type 1 fimbriae in the transformants. (
  • A. viscosus MY50D and MY51S lacked type 1 fimbriae and did not bind to proline-rich proteins (the fimbrial receptors) immobilized on nitrocellulose. (