Identification of Actinobacillus suis genes essential for the colonization of the upper respiratory tract of swine. (1/8)Actinobacillus suis has emerged as an important opportunistic pathogen of high-health-status swine. A colonization challenge method was developed, and using PCR-based signature-tagged transposon mutagenesis, 13 genes belonging to 9 different functional classes were identified that were necessary for A. suis colonization of the upper respiratory tract of swine. (+info)
Enhanced resistance to bacterial infection in protegrin-1 transgenic mice. (2/8)(+info)
Prevalence of Actinobacillus pleuropneumoniae, Actinobacillus suis, Haemophilus parasuis, Pasteurella multocida, and Streptococcus suis in representative Ontario swine herds. (3/8)Tonsillar and nasal swabs were collected from weanling pigs in 50 representative Ontario swine herds and tested for the presence of 5 important bacterial upper respiratory tract pathogens. All but 1 herd (2%) tested positive for Streptococcus suis by polymerase chain reaction (PCR); 48% of herds were S. suis serovar 2, 1/2 positive. In all but 2 herds there was evidence of Haemophilus parasuis infection. In contrast, toxigenic strains of Pasteurella multocida were detected by a P. multocida--enzyme-linked immunosorbant assay (PMT-ELISA) in only one herd. Seventy-eight percent of the herds were diagnosed positive for Actinobacillus pleuropneumoniae by apxIV PCR. Sera from finishing pigs on the same farms were also collected and tested by ELISA for the presence of A. pleuropneumoniae antibodies. Seventy percent of the herds tested had evidence of antibodies to A. pleuropneumoniae including serovars 1-9-11 (2%), 2 (4%), 3-6-8-15 (15%), 5 (6%), 4-7 (26%), and 12 (17%). This likely represents a shift from previous years when infection with A. pleuropneumoniae serovars 1, 5, and 7 predominated. At least 16% and possibly as many as 94% of the herds tested were Actinobacillus suis positive; only 3 of the 50 herds were both A. pleuropneumoniae and A. suis negative as judged by the absence of a positive PCR test for apxII. Taken together, these data suggest that over the past 10 years, there has been a shift in the presence of pathogenic bacteria carried by healthy Ontario swine with the virtual elimination of toxigenic strains of P. multocida and a move to less virulent A. pleuropneumoniae serovars. As well, there appears to be an increase in prevalence of S. suis serovar 2, 1/2, but this may be a reflection of the use of a more sensitive detection method. (+info)
Common sialylated glycan in Actinobacillus suis. (4/8)(+info)
Structural variations within the transferrin binding site on transferrin-binding protein B, TbpB. (5/8)(+info)
Conserved interaction between transferrin and transferrin-binding proteins from porcine pathogens. (6/8)(+info)
Development of a real-time polymerase chain reaction assay for detection of Actinobacillus suis in porcine lung. (7/8)(+info)
Complete genome sequence of Actinobacillus suis H91-0380, a virulent serotype O2 strain. (8/8)(+info)
Actinobacillus suis is a gram-negative, facultative anaerobic bacterium that belongs to the family Pasteurellaceae. It is a common inhabitant of the upper respiratory tract and the genital tract of pigs, and it can also be found in the environment. In the medical field, A. suis is primarily associated with infections in pigs, particularly in the respiratory tract, where it can cause pneumonia, bronchitis, and tracheitis. It can also cause septicemia, meningitis, and endocarditis in pigs. In humans, A. suis infections are rare and are usually associated with close contact with infected pigs or exposure to contaminated animal products. Infections in humans can cause respiratory tract infections, skin and soft tissue infections, and septicemia. The diagnosis of A. suis infections is usually made based on clinical signs and symptoms, as well as laboratory tests such as culture and identification of the bacteria. Treatment typically involves antibiotics, such as penicillin or amoxicillin, and supportive care.
Actinobacillus is a genus of Gram-negative bacteria that are commonly found in the environment and in the upper respiratory tract of animals, including humans. Some species of Actinobacillus are pathogenic and can cause infections in humans and animals, particularly in the respiratory and urinary tracts. The most well-known species of Actinobacillus is Actinobacillus pleuropneumoniae, which is a major cause of respiratory disease in pigs. Other species of Actinobacillus that can cause infections in humans include Actinobacillus actinomycetemcomitans, which can cause periodontal disease, and Actinobacillus suis, which can cause respiratory and systemic infections in pigs. Actinobacillus bacteria are typically identified using microbiological techniques such as culture and biochemical testing. Treatment of Actinobacillus infections typically involves the use of antibiotics, although the choice of antibiotic may depend on the specific species of Actinobacillus involved and the severity of the infection.
Actinobacillus infections are bacterial infections caused by species of the genus Actinobacillus. These bacteria are gram-negative, rod-shaped bacteria that are commonly found in the environment and in the respiratory and gastrointestinal tracts of animals, including humans. Actinobacillus infections can affect a variety of organs and tissues in the body, including the lungs, urinary tract, skin, and joints. Some common types of Actinobacillus infections include: * Actinobacillosis: a severe infection that can affect the lungs, liver, and other organs, and is often seen in cattle and sheep. * Actinomycosis: a chronic infection that can affect the skin, bones, and other tissues, and is often seen in people with weakened immune systems. * Actinobacillary dysentery: a type of diarrhea that is caused by the bacterium Actinobacillus actinomycetemcomitans and is commonly seen in children in developing countries. Actinobacillus infections are typically treated with antibiotics, although the specific antibiotic used will depend on the type of infection and the location of the infection in the body. In severe cases, hospitalization may be necessary for intravenous antibiotics and supportive care.
Actinobacillus pleuropneumoniae is a gram-negative, non-motile, non-spore-forming bacterium that belongs to the family Pasteurellaceae. It is a major pathogen of pigs, causing a highly contagious respiratory disease known as porcine pleuropneumonia or porcine lung (PLD). The disease is characterized by acute or chronic inflammation of the lungs, pleura, and other organs, leading to coughing, difficulty breathing, and weight loss in affected pigs. Actinobacillus pleuropneumoniae is transmitted through the air, primarily by direct contact between infected and susceptible pigs, or by contaminated fomites such as feed and water. The bacteria can survive for long periods in the environment and on the skin and mucous membranes of infected pigs. There are 15 recognized serotypes of Actinobacillus pleuropneumoniae, each with different virulence characteristics. The severity of the disease and the response to treatment can vary depending on the serotype and the immune status of the pigs. Diagnosis of PLD is typically based on clinical signs, post-mortem examination, and laboratory tests such as bacterial culture and serotyping. Treatment of PLD involves the use of antibiotics, such as penicillin or tetracycline, to control the infection and prevent its spread. Prevention measures include vaccination, good hygiene practices, and the use of antibiotics in feed to control the carrier state of infected pigs.
Swine diseases refer to any illness or infection that affects pigs. These diseases can be caused by a variety of factors, including viruses, bacteria, parasites, fungi, and environmental factors. Swine diseases can range from mild to severe and can affect pigs of all ages and sizes. Some common swine diseases include: 1. Porcine Reproductive and Respiratory Syndrome (PRRS) 2. Swine Influenza (Swine Flu) 3. Porcine Circovirus Type 2 (PCV2) 4. Porcine Parvovirus (PPV) 5. Porcine Epidemic Diarrhea (PED) 6. Swine Leukosis Virus (SLV) 7. Porcine Dermatitis and Necrosis Syndrome (PDNS) 8. Porcine Enterotoxemia (PED) 9. Porcine Circovirus Type 1 (PCV1) 10. Porcine Circovirus Type 3 (PCV3) Swine diseases can have significant economic impacts on the pork industry, as well as on animal welfare and public health. Therefore, it is important for veterinarians, farmers, and other stakeholders to be aware of the signs and symptoms of swine diseases and to take appropriate measures to prevent and control their spread.
Aggregatibacter actinomycetemcomitans is a Gram-negative, facultative anaerobic bacterium that is commonly found in the oral cavity of humans and animals. It is a member of the normal oral microbiota and is often associated with periodontal disease, particularly aggressive periodontitis, which is a severe form of periodontal disease that affects young adults. A. actinomycetemcomitans is also associated with other infections, including endocarditis, brain abscesses, and infections of the skin and soft tissues. It has been classified as a group B streptococcus and is considered a potential pathogen in certain situations. The bacterium is known for its ability to form aggregates or biofilms, which can contribute to its virulence and resistance to antibiotics. It is also capable of producing a number of virulence factors, including toxins and enzymes that can damage host tissues and evade the immune system. In the medical field, A. actinomycetemcomitans is typically identified using culture and molecular techniques, such as polymerase chain reaction (PCR) and DNA sequencing. Treatment of infections caused by this bacterium typically involves antibiotics, although the effectiveness of these treatments can vary depending on the specific strain of the bacterium and the severity of the infection.
Brucella suis is a gram-negative, facultative intracellular bacterium that belongs to the genus Brucella. It is a zoonotic pathogen, meaning it can be transmitted from animals to humans. B. suis is primarily found in pigs and is responsible for causing brucellosis in pigs, which is also known as swine brucellosis. The bacteria can also infect other animals, including cattle, sheep, goats, and dogs. In humans, B. suis can cause a disease called brucellosis, which is also known as undulant fever. Symptoms of brucellosis in humans can include fever, sweats, headache, muscle and joint pain, fatigue, and weakness. In severe cases, the disease can cause more serious complications, such as endocarditis (inflammation of the heart valves) and meningitis (inflammation of the membranes surrounding the brain and spinal cord). Brucella suis is a highly contagious pathogen, and it can be transmitted to humans through direct contact with infected animals or their bodily fluids, such as milk or semen. It can also be transmitted through the consumption of contaminated food or water.
Pleuropneumonia is a type of lung infection that affects both the pleura (the lining of the lungs) and the parenchyma (the tissue of the lungs). It is caused by a variety of bacteria, viruses, or fungi, and can be acute or chronic in nature. The symptoms of pleuropneumonia can include fever, cough, chest pain, difficulty breathing, and fatigue. In severe cases, it can lead to pneumonia, which is an infection of the alveoli (tiny air sacs) in the lungs. Pleuropneumonia is typically diagnosed through a combination of physical examination, medical history, and diagnostic tests such as chest X-rays, blood tests, and sputum cultures. Treatment typically involves antibiotics or antifungal medications, depending on the cause of the infection. In some cases, hospitalization may be necessary for severe cases or to provide supportive care.
Actinobacillus equuli is a type of bacteria that is commonly found in the upper respiratory tract of horses. It is a Gram-negative, facultative anaerobic bacterium that can cause a variety of infections in horses, including pneumonia, endocarditis, and septicemia. Infections caused by Actinobacillus equuli are typically more common in young horses and horses with weakened immune systems. The bacteria can be transmitted from horse to horse through respiratory droplets or by direct contact with infected bodily fluids. Symptoms of Actinobacillus equuli infection can include fever, coughing, difficulty breathing, and rapid heart rate. Treatment typically involves the use of antibiotics, although the specific antibiotic used may depend on the severity of the infection and the resistance patterns of the bacteria. In some cases, Actinobacillus equuli infections can be life-threatening, particularly if they involve the heart or other vital organs. Therefore, prompt diagnosis and treatment are important for ensuring the best possible outcome for affected horses.
Aggressive periodontitis, also known as adult periodontitis, is a type of periodontal disease that is characterized by rapid and severe destruction of the gums and supporting bone around the teeth. It typically occurs in individuals under the age of 35 and is often familial, meaning that it runs in families. The exact cause of aggressive periodontitis is not fully understood, but it is believed to be related to a combination of genetic and environmental factors. Risk factors for aggressive periodontitis include smoking, poor oral hygiene, and certain medical conditions such as diabetes and HIV. Symptoms of aggressive periodontitis may include red, swollen, and bleeding gums, loose teeth, and persistent bad breath. Treatment typically involves scaling and root planing, which involves removing plaque and tartar from the teeth and smoothing the root surfaces to promote healing. In some cases, surgery may be necessary to remove infected tissue or to stabilize the teeth. Aggressive periodontitis can have serious consequences if left untreated, as it can lead to tooth loss and other complications. Early detection and treatment are important for managing this condition and preventing further damage to the teeth and gums.
Periodontitis is a chronic inflammatory disease that affects the gums and the tissues that support the teeth. It is caused by the buildup of plaque, a sticky film of bacteria that forms on the teeth and gums. Over time, plaque hardens into tartar, which can irritate the gums and cause them to become red, swollen, and tender. If left untreated, periodontitis can lead to the loss of teeth and bone. Periodontitis is typically divided into two stages: gingivitis and periodontitis. Gingivitis is the mildest form of the disease and is characterized by red, swollen gums that bleed easily when brushed or flossed. Periodontitis, on the other hand, is more severe and can cause the gums to pull away from the teeth, forming pockets that can become infected with bacteria. In advanced cases, periodontitis can lead to the loss of bone that supports the teeth, causing them to become loose and eventually fall out. Treatment for periodontitis typically involves a combination of professional cleanings, antibiotics, and surgery to remove infected tissue and bone. Good oral hygiene habits, such as brushing and flossing regularly, can help prevent the development of periodontitis.
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Actinobacillus suis - Wikipedia
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- Signs and necropsy findings may mimic diseases such as erysipelas, Glasser's disease, and Streptococcus suis or Actinobacillus pleuropneumoniae infection. (wikipedia.org)
- The objective of this study was to estimate the prevalence and changes in resistance to 13 antimicrobials in swine bacterial pathogens ( Streptococcus suis , Pasteurella multocida , Actinobacillus suis and Haemophilus parasuis ) in the U.S.A using data collected at University of Minnesota Veterinary Diagnostic Laboratory between 2006 and 2016. (umnswinenews.com)
- Tenotryl is also indicated for treatment and control of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, Streptococcus suis, Bordetella bronchiseptica, and Mycoplasma hyopneumoniae in swine. (valleyvet.com)
- In pigs: For the treatment of bacterial respiratory disease in which Actinobacillus (Haemophilus) pleuropneumoniae, Pasteurella multocida and Streptococcus suis sensitive to Ceftiofur are involved. (tdnid.com)
- 6. Ichikawa T, Oshima M, Yamagishi J, Muramatsu C, Asai T. Changes in antimicrobial resistance phenotypes and genotypes in Streptococcus suis strains isolated from pigs in the Tokai area of Japan. (gifu-u.ac.jp)
- AE24 ACIN2 Acinetobacter venetianus Aven Acrocarpospora corrugata Acor Acrocarpospora pleiomorpha Aple Actinoallomurus spadix Aspa Actinoalloteichus cyanogriseus Acya Actinobacillus capsulatus Acap1 Actinobacillus equuli Aequ Actinobacillus hominis Ahom Actinobacillus indolicus Aind Actinobacillus lignieresii Alig Actinobacillus minor Amin1 Actinobacillus muris Amur Actinobacillus pleuropneumoniae Aple1 Actinobacillus pleuropneumoniae serovar 1 str. (uni-freiburg.de)
- 4074 Aple1_A Actinobacillus pleuropneumoniae serovar 3 str. (uni-freiburg.de)
- JL03 Aple1_C Actinobacillus pleuropneumoniae serovar 5b str. (uni-freiburg.de)
- L20 Aple1_B Actinobacillus pleuropneumoniae serovar 7 str. (uni-freiburg.de)
- 18. Ito H, Takahashi S, Asai T, Tamura Y, Yamamoto K. Isolation and molecular characterization of a urease-negative Actinobacillus pleuropneumoniae mutant. (gifu-u.ac.jp)
- SHIC's Rapid Response Program investigation of the Actinobacillus pleuropneumoniae outbreak in the Midwest exposed deficiencies of wean-to-harvest biosecurity that contributed to disease spread. (swinehealth.org)
- For antimicrobial-bacterial combinations without available breakpoints, the odds of isolates being resistant increased by >10% annually for 7 and 1 antimicrobials in H. parasuis and S. suis isolates respectively, and decreased >10% annually for 4 and 1 antimicrobials in A. suis and H. parasuis isolates, respectively, according to the ordinal regression models. (umnswinenews.com)
- A species of gram-negative bacteria in the genus ACTINOBACILLUS . (nih.gov)
- HN - 2004 MH - Actinobacillus equuli UI - D044131 MN - B3.440.450.09.200 MN - B3.660.250.550.50.200 MS - A genus of gram-negative bacteria in the genus ACTINOBACILLUS, which is pathogenic for HORSES and PIGS. (nih.gov)
- AN - infection: coord IM with ACTINOBACILLUS INFECTIONS (IM) HN - 2004 MH - Actinobacillus seminis UI - D044133 MN - B3.440.450.09.675 MN - B3.660.250.550.50.675 MS - A species of gram-negative bacteria in the genus ACTINOBACILLUS, which causes EPIDIDYMITIS in SHEEP. (nih.gov)
- AN - infection: coord IM with ACTINOBACILLUS INFECTIONS (IM) + EPIDIDYMITIS (IM) if pertinent HN - 2004 MH - Actinobacillus suis UI - D044132 MN - B3.440.450.09.700 MN - B3.660.250.550.50.700 MS - A species of gram-negative bacteria in the genus ACTINOBACILLUS. (nih.gov)
- AN - infection: coord IM with ACTINOBACILLUS INFECTIONS (IM) HN - 2004 MH - Acyl-CoA Dehydrogenase UI - D042964 MN - D8.811.682.675.150.100 MN - D12.776.331.99 MS - A flavoprotein oxidoreductase that has specificity for medium-chain fatty acids. (nih.gov)