Infections with bacteria of the genus ACTINOBACILLUS.
A genus of PASTEURELLACEAE described as gram-negative, nonsporeforming, nonmotile, facultative anaerobes. Most members are found both as pathogens and commensal organisms in the respiratory, alimentary, and genital tracts of animals.
A species of gram-negative, facultatively anaerobic coccobacillus-shaped bacteria that has been isolated from pneumonic lesions and blood. It produces pneumonia with accompanying fibrinous pleuritis in swine.
A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.
A species of gram-negative bacteria in the genus ACTINOBACILLUS. It is mainly a pathogen of PIGS, but also can infect HORSES.
Inflammation of the lung parenchyma that is associated with PLEURISY, inflammation of the PLEURA.
A genus of gram-negative bacteria in the genus ACTINOBACILLUS, which is pathogenic for HORSES and PIGS.
Diseases of domestic swine and of the wild boar of the genus Sus.
A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.
Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
A genus of PASTEURELLACEAE. Members are nonmotile, Gram-negative, facultatively anaerobic rods or coccobacilli. Its members are X factor (HEMIN) independent and variably dependent on V factor (NAD).
Toxins produced, especially by bacterial or fungal cells, and released into the culture medium or environment.
A family of coccoid to rod-shaped nonsporeforming, gram-negative, nonmotile, facultatively anaerobic bacteria that includes the genera ACTINOBACILLUS; HAEMOPHILUS; MANNHEIMIA; and PASTEURELLA.
The oldest recognized genus of the family PASTEURELLACEAE. It consists of several species. Its organisms occur most frequently as coccobacillus or rod-shaped and are gram-negative, nonmotile, facultative anaerobes. Species of this genus are found in both animals and humans.
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
A disease characterized by suppurative and granulomatous lesions in the respiratory tract, upper alimentary tract, skin, kidneys, joints, and other tissues. Actinobacillus lignieresii infects cattle and sheep while A. equuli infects horses and pigs.
Proteins from BACTERIA and FUNGI that are soluble enough to be secreted to target ERYTHROCYTES and insert into the membrane to form beta-barrel pores. Biosynthesis may be regulated by HEMOLYSIN FACTORS.
A species of gram-negative bacteria in the genus ACTINOBACILLUS, which causes EPIDIDYMITIS in SHEEP.
Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Oral tissue surrounding and attached to TEETH.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Proteins found in any species of bacterium.
A class of carrier proteins that bind to TRANSFERRIN. Many strains of pathogenic bacteria utilize transferrin-binding proteins to acquire their supply of iron from serum.
A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
The functional hereditary units of BACTERIA.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A saclike, glandular diverticulum on each ductus deferens in male vertebrates. It is united with the excretory duct and serves for temporary storage of semen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Planning, organizing, staffing, direction, and control of libraries.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.
Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.
The heritable modification of the properties of a competent bacterium by naked DNA from another source. The uptake of naked DNA is a naturally occuring phenomenon in some bacteria. It is often used as a GENE TRANSFER TECHNIQUE.
Uncontrolled release of biological material from its containment. This either threatens to, or does, cause exposure to a biological hazard. Such an incident may occur accidentally or deliberately.
A species of parasitic protozoa found in the intestines of humans and other primates. It was classified as a yeast in 1912. Over the years, questions arose about this designation. In 1967, many physiological and morphological B. hominis characteristics were reported that fit a protozoan classification. Since that time, other papers have corroborated this work and the organism is now recognized as a protozoan parasite of humans causing intestinal disease with potentially disabling symptoms.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Vaccines used to prevent TYPHOID FEVER and/or PARATYPHOID FEVER which are caused by various species of SALMONELLA. Attenuated, subunit, and inactivated forms of the vaccines exist.
Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.
An acute systemic febrile infection caused by SALMONELLA TYPHI, a serotype of SALMONELLA ENTERICA.
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)
Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins.
That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.
A genus of GRAM-POSITIVE ENDOSPORE-FORMING RODS, in the family Alicyclobacillaceae, containing a unique lipid in their membranes.
Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.
Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified.

Pulmonary lesions in guinea pigs experimentally infected with Actinobacillus pleuropneumoniae (A.p.) serovar 1. (1/272)

Pathological studies were carried out on the lungs of guinea pigs intratracheally inoculated with 4.6 x 10(6-8) colony forming units (CFU)/head of Actinobacillus pleuropneumoniae serovar 1. All animals in the highest dose group died within 24 hr post inoculation (hpi) and showed pulmonary lesions being hemorrhagic in nature while all animals in the lowest dose group were killed as scheduled at 11 days post inoculation (dpi) and showed only hyperplasia of peribronchial lymphoid tissues. In the middle dose group, two died within 24 hpi, two died at 9 dpi, and the remaining one was killed at 11 dpi. Two guinea pigs which died at 9 dpi showed fibrinonecrotic pleuropneumonia which is the most characteristic acute pulmonary lesion in swine, and has not yet been reproduced in laboratory animals up to the present time. This suggests that guinea pigs may be a useful laboratory animal for studying the pathogenesis of Actinobacillus pleuropneumoniae infection in swine.  (+info)

Vaccination and protection of pigs against pleuropneumonia with a vaccine strain of Actinobacillus pleuropneumoniae produced by site-specific mutagenesis of the ApxII operon. (2/272)

The production of toxin (Apx)-neutralizing antibodies during infection plays a major role in the induction of protective immunity to Actinobacillus pleuropneumoniae reinfection. In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Expression of the structural toxin, ApxIIA, and of the two genes required for its secretion, apxIB and apxID, still occurs in this strain. The resulting mutant strain, HS93C- Ampr, was found to secrete the unactivated toxin. Pigs vaccinated with live HS93C- Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae. This is the first reported vaccine strain of A. pleuropneumoniae which can be delivered live to pigs and offers cross-serovar protection against porcine pleuropneumonia.  (+info)

Actinobacillus pleuropneumoniae osteomyelitis in pigs demonstrated by fluorescent in situ hybridization. (3/272)

Necrotizing osteomyelitis and fibrinopurulent arthritis with isolation of Actinobacillus pleuropneumoniae serotype 2 is reported in two pigs from a herd with lameness and mild coughing problems among 8 to 12-week-old pigs. Application of fluorescent in situ hybridization targeting 16S ribosomal RNA of A. pleuropneumoniae in formalin-fixed tissue was performed to verify the association of A. pleuropneumoniae with the bone and joint lesions. By in situ hybridization A. pleuropneumoniae was demonstrated as multiple microcolonies or single cells dispersed in focal fibrinonecrotizing pleuropneumonia, in joints with arthritis, and in bone necroses including lysis of growth plate and suppurative inflammation in the adjacent trabecular metaphysis, thus demonstrating that well-known infections manifest new, unusual lesions.  (+info)

Agents of the "suis-ide diseases" of swine: Actinobacillus suis, Haemophilus parasuis, and Streptococcus suis. (4/272)

In recent years, Actinobacillus suis, Haemophilus parasuis, and Streptococcus suis have emerged as important pathogens of swine, particularly in high health status herds. Their association with a wide range of serious clinical conditions and has given rise to the moniker "suis-ide diseases." These organisms are early colonizers and, for that reason, are difficult to control by management procedures such as segregated early weaning. Vaccination, serodiagnostic testing, and even serotyping are complicated by the presence of multiple serotypes, cross-reactive antigens, and the absence of clear markers for virulence. In this review, we discuss our current understanding of the pathogenesis, epidemiology, and management of the causative agents of the "suis-ide diseases" of swine.  (+info)

Phenotypic variation in Actinobacillus actinomycetemcomitans during laboratory growth: implications for virulence. (5/272)

This study examined alteration of specific virulence traits associated with phenotypic changes seen when a low-passage disease-associated and well maintained parent strain of Actinobacillus actinomycetemcomitans was compared to a laboratory-grown spontaneous variant/mutant. Clinical isolates of A. actinomycetemcomitans recovered from periodontitis patients typically grow as rough, adherent colonies on primary culture but undergo transformation to smooth, non-adherent colonies following repeated passage in vitro. The relationship of these phenotypic changes to the virulence of the organism or to the processes that underlie this transformation are not understood. A fresh clinical isolate, designated strain CU1000, was obtained from the first molar site of a patient with classical signs of localized juvenile periodontitis and used as the parent strain to study virulence-related phenotypes. Following several passages of CU1000 on selective agar, a spontaneous variant that demonstrated smooth, opaque, non-adherent colonies was isolated and designated strain CU1060. This study compared the properties of these two strains with respect to colony morphology, autoaggregation, surface appendages, adherence to saliva-coated hydroxyapatite (SHA), LPS chemotype and activity, induction of fibroblast proteinase activity and antigenic properties. CU1000 demonstrated rough, raised, star-positive colonies which upon electron microscopic examination revealed the presence of large, flexible, bundled fibrils. In addition, CU1000 showed adherence to SHA, several unique protein antigens and elevated endotoxin and fibroblast proteinase activity. CU1060, on the other hand, showed minimal adherence to SHA and fewer reactive proteins compared to the fresh clinical isolates. This strain formed smooth, opaque colonies on agar, showed minimal fibril formation and limited endotoxin and fibroblast-proteinase-inducing activity. These findings demonstrate that clinical isolates of A. actinomycetemcomitans undergo significant virulence-reducing phenotypic alterations during in vitro passage and support the need to study this organism in its clinical form.  (+info)

Detection of antibodies against Actinobacillus pleuropneumoniae serotypes 1, 2, 5 and 7 using the immunohistochemical staining. (6/272)

Whole cells of Actinobacillus pleuropneumoniae (A. pleuropneumoniae) serotype 1, 2, 5 or 7 attached to fibrins were fixed in 10% neutral buffered formalin and embedded in paraffin. The sections on a slide glass were stained by the avidin-biotin complex immunoperoxidase (ABC) method. Test sera were applied to sections as primary antibodies. The serum antibodies against A.pleuropneumoniae (serotypes 1, 2, 5 and 7) were measured by the ABC method and complement fixation (CF) test. There was good correlation between the ABC and CF tests. The present results indicate that the immunohistochemical staining is as useful as the CF test for the detection and quantification of antibody in swine sera.  (+info)

Characterization of apxIVA, a new RTX determinant of Actinobacillus pleuropneumoniae. (7/272)

A fourth type of RTX determinant was identified in Actinobacillus pleuropneumoniae and was designated apxIVA. When expressed in Escherichia coli, recombinant ApxIVA showed a weak haemolytic activity and co-haemolytic synergy with the sphingomyelinase (beta-toxin) of Staphylococcus aureus. These activities required the presence of an additional gene, ORF1, that is located immediately upstream of apxIVA. The apxIVA gene product could not be detected in A. pleuropneumoniae cultures grown under various conditions in vitro; however, pigs experimentally infected with A. pleuropneumoniae serotypes 1, 5 and 7 started to produce antibodies that reacted with recombinant ApxIVA 14 d post-infection, indicating that apxIVA is expressed in vivo. In addition, sera from pigs naturally and experimentally infected with any of the serotypes all reacted with recombinant ApxIVA. The apxIVA gene from the serotype 1 A. pleuropneumoniae type strain Shope 4074T encodes a protein with a predicted molecular mass of 202 kDa which has typical features of RTX proteins including hydrophobic domains in the N-terminal half and 24 glycine-rich nonapeptides in the C-terminal half that bind Ca2+. The glycine-rich nonapeptides are arranged in a modular structure and there is some variability in the number of modules in the ApxIVA proteins of different serotypes of A. pleuropneumoniae. The deduced amino acid sequences of the ApxIVA proteins have significant similarity with the Neisseria meningitidis iron-regulated RTX proteins FrpA and FrpC, and to a much lesser extent with other RTX proteins. The apxIVA gene could be detected in all A. pleuropneumoniae serotypes and seems to be species-specific. Although the precise role of this new RTX determinant in pathogenesis of porcine pleuropneumonia needs to be determined, apxIVA is the first in vivo induced toxin gene that has been described in A. pleuropneumoniae.  (+info)

Genomic relatedness among Actinobacillus pleuropneumoniae field strains of sterotypes 1 and 5 isolated from healthy and diseased pigs. (8/272)

Forty-four Actinobacillus pleuropneumoniae isolates recovered from both healthy and diseased pigs were characterized by random amplified polymorphic DNA analysis (RAPD), pulsed field gel electrophoresis (PFGE) and apx toxin gene typing. Nine RAPD types and 14 PFGE patterns were identified. No common RAPD or PFGE patterns were found between strains of serotype 1 and those of serotype 5. The RAPD analysis indicated that the 15 serotype 1 strains isolated from diseased pigs were assigned to 4 RAPD types, with 66% of strains characterized by the same RAPD type. By contrast, the 5 strains of serotype 1 isolated from healthy carriers were dispersed in 4 RAPD types. These data suggest that the diversity of strains isolated from healthy pigs could be higher than that of strains recovered from diseased pigs. In addition, all serotype 5 strains exhibited a unique RAPD type. Unlike RAPD, PFGE analysis allowed discrimination among isolates of serotype 1 and among those of serotype 5. All but 3 isolates showed the same apx genotype as their respective serotype reference strain. These data indicate that RAPD analysis is a valuable rapid tool for routine subtyping of strains of serotype 1. For strains of serotype 5, a combination of several typing methods, such as PFGE and apx gene typing, is needed to provide useful information on the molecular epidemiology of swine pleuropneumonia.  (+info)

TY - JOUR. T1 - Actinobacillus pleuropneumoniae serotypes in Hungary. AU - Sárközi, Rita. AU - Makrai, L.. AU - Fodor, L.. PY - 2018/9/1. Y1 - 2018/9/1. N2 - A total of 255 Actinobacillus pleuropneumoniae isolates were collected from 634 lung samples representing 70 swine herds in Hungary between January 2012 and June 2016. On the basis of the indirect haemagglutination test 77 independent strains were included in the evaluation after the elimination of duplicate or multiple serotypes from the same herd. In the case of 7 herds strains of two different serotypes were identified. Fourteen Hungarian A. pleuropneumoniae isolates from the culture collection of the Department of Microbiology and Infectious Diseases, isolated before 2012, were also included in the evaluation (one each from 12 herds and two each from two herds, where two serotypes occurred). Out of the altogether 91 A. pleuropneumoniae strains 72 strains belonged to biotype I and 19 strains could be allocated to biotype II. In ...
In Denmark porcine pleuropneumonia is most frequently caused by Actinobacillus pleuropneumoniae serotype 2 (60%). Isolation of A. pleuropneumoniae from nasal cavities or tonsils from carrier animals is complicated due to the mixed bacterial flora present. An immunomagnetic separation technique (IMS) using immunomagnetic beads (Dynabeads(R)) was developed for isolation of A. pleuropneumoniae serotype 2 from pure cultures and from heterogeneous suspensions. Different coating and washing procedures were evaluated in pure and mixed cultures using polyclonal (PAb) and monoclonal antibodies. The highest reisolation yield was achieved when the beads were coated with 1.5 mug PAb IgG/10(7) beads. After washing the beads for four times 9-24% of the bacteria could be reisolated depending on the amount of IgG attached to the beads and the number of beads used. The recovery was increased to 19-61% when only two washing steps were performed. The IMS was further evaluated using dilutions of A. pleuropneumoniae ...
article{176028, author = {Haesebrouck, Freddy and Chiers, Koen and Van Overbeke, Ingrid and Ducatelle, Richard}, issn = {0378-1135}, journal = {VETERINARY MICROBIOLOGY}, language = {eng}, number = {2-4}, pages = {239--249}, title = {Actinobacillus pleuropneumoniae infections in pigs: the role of virulence factors in pathogenesis and protection.}, volume = {58}, year = {1997 ...
Actinobacillus pleuropneumoniae serotype 3 UPF0263 protein APJL_1366 (APJL_1366) datasheet and description hight quality product and Backed by our Guarantee
Serotypes 3 and 8 of Actinobacillus pleuropneumoniae, the aetiological agent of porcine pleuropneumonia, have been reported to predominate in the UK. Direct serotyping of isolates of the organism is typically determined by the immunological reactivity of rabbit serum to its surface polysaccharides, but the method has limitations, for example, cross-reactions between serotypes 3, 6 and 8. This study describes the development of a serotype 3-specific PCR, based on the capsule locus, which can be used in a multiplex format with the organisms specific gene apxIV. The PCR test was evaluated on 266 strains of A pleuropneumoniae and 121 strains of other organisms, including all the major respiratory bacterial pathogens of pigs. The test was highly specific and sensitive and should be useful for differentiating strains of serotypes 3, 6 and 8, and in seroprevalence and epidemiological surveys in regions where serotype 3 is prevalent, such as the UK.. ...
Actinobacillus pleuropneumoniae is a Gram-negative bacterium and a member of the Pasteurellaceae family. This bacterium is the causative agent of porcine pleuropneumonia, which is a highly contagious respiratory disease causing important economical losses to the worldwide pig industry. It has been shown that A. pleuropneumoniae can form biofilms on abiotic surfaces (plastic and glass). Although in vitro models are extremely useful to gain information on biofilm formation, these models may not be representative of the conditions found at the mucosal surface of the host, which is the natural niche of A. pleuropneumoniae. In this paper, we describe a method to grow A. pleuropneumoniae biofilms on the SJPL cell line, which represents a biotic surface. A non-hemolytic, non-cytotoxic mutant of A. pleuropneumoniae was used in our assays and this allowed the SJPL cell monolayers to be exposed to A. pleuropneumoniae for longer periods. This resulted in the formation of biofilms on the cell monolayer after
Actinobacillus pleuropneumoniae (previously Haemophilus pleuropneumoniae), is a Gram-negative, facultative anaerobic, respiratory pathogen found in pigs. It was first reported in 1957, and was formally declared to be the causative agent of porcine pleuropneumonia in 1964. It was reclassified in 1983 after DNA studies showed it was more closely related to A. lignieresii. A. pleuropneumoniae is a nonmotile, Gram-negative, encapsulated coccobacillus bacterium found in the Pasteurellaceae family. It exhibits β-hemolysis activity, thus explaining its growth on chocolate or blood agar, but must be supplemented with NAD (V factor) to facilitate growth for one of its biological variants (biovar 1). As a facultative anaerobic pathogen, A. pleuropneumoniae may need CO2 to grow. Depending on the biovar, the bacteria may or may not be positive for urease; both biovars are positive for porphyrin. A. pleuropneumoniae was found to be the causative agent for up to 20% of all bacterial pneumonia cases in ...
Fifty randomly selected fattening pig herds were studied to investigate the epidemiological characteristics of infections with Actinobacillus pleuropneumoniae serovars 2, 3 and 9, and to identify risk factors for their within-herd seroprevalences. Information about 13 farm characteristics was obtained by means of a questionnaire and used to assess potential risk factors for the percentage of slaughter pigs with antibodies against each of the three serovars. The presence of antibodies was measured with an indirect ELISA. The median within-herd seroprevalence for serovar 2 was 58 per cent (range 0 to 100 per cent), for serovar 3, 53 per cent (range 10 to 95 per cent), and for serovar 9, 35 per cent (range 5 to 100 per cent). All but one farm tested positive for A pleuropneumoniae serovar 2, and all the farms were positive for A pleuropneumoniae serovars 3 and 9. There was a positive association (P<0.05) between each pair of serovars. The within-herd seroprevalence of serovar 2 was ...
Biomarkers of infection were screened for their possible role as evaluators of antibiotic treatment in an aerosol infection model of porcine pneumonia caused by Actinobacillus pleuropneumoniae (Ap). Following infection of 12 pigs, clinical signs of pneumonia developed within 20 h, whereafter the animals received a single dose of either danofloxacin (2.5 mg/kg) or tiamulin (10 mg/kg). To test the discriminative properties of the biomarkers, the dosage regimens were designed with an expected difference in therapeutic efficacy in favour of danofloxacin. Accordingly, the danofloxacin-treated pigs recovered clinically within 24h after treatment, whereas tiamulin-treated animals remained clinically ill until the end of the study, 48 h after treatment. A similar Picture was seen for the biomarkers of infection. During the infection period, plasma C-reactive protein (CRP), interleukin-6 and haptoglobin increased, whereas plasma zinc, ascorbic acid and alpha-tocopherol decreased. In the ...
Actinobacillus pleuropneumoniae ApaA protein: an antigenic membrane protein from Actinobacillus pleuropnemoniae homology to ABC transporters; amino acid sequence in first source
0004] It is commonly known how to produce the RTX-toxin ApxI by culturing Actinobacillus pleuropneumoniae in a culturing medium to which a calcium salt (i.e. a chemical compound, based on an acid, formed by replacing all or part of the hydrogen ions of the acid with one or more calcium ions) is added. In particular, EP 0 453 024 already describes such a method (see Example 2, paragraph 2 Purification and characterisation of hemolysin, subparagraph Methods). Note that ApxI used to be referred to as HLY (see Frey et al. in J Gen Microbiol. 1993 August; 139(8): 1723-8). From this EP patent it is known to add a calcium compound (CaCl2) to the medium. Indeed, in Microbiol Pathogenesis 37 (2004) 29-33 it is stated that transcriptional activity of the ApxI operon is enhanced by addition of calcium to the growth medium. This way, high levels of ApxI can be provided for. The medium should support the growth of APP bacteria. It is commonly known how to constitute a medium that supports growth of ...
Pleuropneumonia infectioasa a porcului (PIP), cauzata de Actinobacillus pleuropneumoniae (App), poate fi intalnita la porcii de toate varstele, inclusiv la mistreti, dar simptomele clinice cele mai frecvente sunt inregistrate la porcii in faza de finisare, in varsta de peste 12 saptamani. In formele clasice de boala animalele manifesta febra si simptome respiratorii, datorate leziunilor caracteristice de pneumonie hemoragico-necrotica sau pleuropneumonie fibrinoasa. Boala poate evolua supra-acut, fara semne clinice, animalele fiind gasite moarte, acut, mai ales in efectivele naive imunologic, cu pierderi prin mortalitate de 15-20%, sau sub-acut, cu mortalitate mai redusa dar variabila. In efectivele infectate endemic boala se cronicizeaza la animalele care au supravietuit, afectand starea lor de bine si producand o scadere a performantelor zootehnice. Porcii pot fi purtatori fara sa dezvolte vreun raspuns imun. Boala genereaza pierderi economice insemnate.. ...
MUNOZ, D; QUEZADA, M y RUIZ, A. Serological behaviour study of Actinobacillus pleuropneumoniae (App) in commercial swine herds from the central region of Chile. Arch. med. vet. [online]. 2008, vol.40, n.2, pp.147-153. ISSN 0301-732X. http://dx.doi.org/10.4067/S0301-732X2008000200006.. In Chile, there was only one existing study on App. This study was designed to determine the maternal immunity duration, the age of seroconversion and the apparent and true prevalence in animals from 7 swine commercial herds. 60 samples were taken per herd and divided into 10 serum samples from animals of 4, 6,10,14,18and21 weeks of age, which were analyzed by ELISA®. Out of the 420 samples, 134 were positive with 112 of them belonging to pigs under 10 weeks of age while only 22 were from animals over 10 weeks of age, which seroconverted presumably due to a natural infection. Regarding maternal immunity duration it was found that around the 10th week of age the animals lose their colostrum antibodies. In ...
Actinobacillus pleuropneumoniae ATCC ® 33590™ Designation: Femo TypeStrain=True Application: Characterization Respiratory research
Actinobacillus pleuropneumoniae, a Gram-negative, non-motile, facultatively anaerobic Pasteurellaceae, causes porcine pleuropneumonia, a highly contagious disease for which there is no effective vaccine. There are least twelve different serotypes, some of which produce no disease but others cause severe disease. Serotypes vary in different countries. Types 1, 5, 9, 11 and 12 are usually highly virulent and strains 3 and 6 are mild. The bacterium is carried in the tonsils and upper respiratory tract. It is transmitted short distances by droplet infection and only survives outside the pig for a few days.Actinobacillus pleuropneumoniae strain JL03 is an isolate of serotype 3 which is prevalent in China. Its genome is made up of a single circular chromosome encoding 2097 CDSs. It possesses a complete set of genes coding for enzymes of glycolysis, gluconeogenesis and non-oxidative pentose phosphate pathways. Genes coding for the key enzymes of the TCA cycle, citrate synthase, aconitase and isocitrate ...
ID ACTP7_1_PE100 STANDARD; PRT; 215 AA. AC ACTP7_1_PE100; B3GZU0; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE SubName: Full=Cytochrome c-type protein NrfB; (ACTP7_1.PE100). GN Name=nrfB; OrderedLocusNames=APP7_0100; OS ACTINOBACILLUS PLEUROPNEUMONIAE SEROVAR 7 STR. AP76. OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; OC Pasteurellaceae; Actinobacillus. OX NCBI_TaxID=537457; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACTP7_1.PE100. CC Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete genome. CC sequence. CC -!- ANNOTATIONS ORIGIN:B3GZU0_ACTP7 CC -!- GENE_FAMILY: HOG000278525 [ FAMILY / ALN / TREE ] DR UniProtKB/Swiss-Prot; B3GZU0; -. DR EMBL; CP001091; ACE60752.1; -; Genomic_DNA. DR RefSeq; YP_001967894.1; NC_010939.1. DR ProteinModelPortal; B3GZU0; -. DR STRING; B3GZU0; -. DR GeneID; 6397435; -. DR GenomeReviews; CP001091_GR; APP7_0100. DR ...
TY - JOUR. T1 - Enhancement of protective immune responses by oral vaccination with Saccharomyces cerevisiae expressing recombinant Actinobacillus pleuropneumoniae ApxIA or ApxIIA in mice. AU - Sung, Jae Shin. AU - Seung, Won Shin. AU - Mi, Lan Kang. AU - Deog, Yong Lee. AU - Yang, Moon Sik. AU - Jang, Yong Suk. AU - Han, Sang Yoo. PY - 2007/12. Y1 - 2007/12. N2 - We previously induced protective immune response by oral immunization with yeast expressing the ApxIIA antigen. The ApxI antigen is also an important factor in the protection against Actinobacillus pleuropneumoniae serotype 5 infection; therefore, the protective immunity in mice following oral immunization with Saccharomyces cerevisiae expressing either ApxIA (group C) or ApxIIA (group D) alone or both (group E) was compared with that in two control groups (group A and B). The immunogenicity of the rApxIA antigen derived from the yeast was confirmed by a high survival rate and an ApxIA-specific IgG antibody response (p , 0.01). The ...
Looking for Actinobacillus capsulatus? Find out information about Actinobacillus capsulatus. A genus of gram-negative, immotile and nonspore-forming, oval to rod-shaped, often pleomorphic bacteria which occur as parasites or pathogens in mammals ,... Explanation of Actinobacillus capsulatus
Pharmacokinetic-pharmacodynamic (PK/PD) integration and modelling were used to predict dosage schedules for florfenicol for two pig pneumonia pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida. Pharmacokinetic data were pooled for two bioequivalent products, pioneer and generic formulations, administered intramuscularly to pigs at a dose rate of 15 mg/kg. Antibacterial potency was determined in vitro as minimum inhibitory concentration (MIC) and Mutant Prevention Concentration in broth and pig serum, for six isolates of each organism. For both organisms and for both serum and broth MICs, average concentration:MIC ratios over 48 h were similar and exceeded 2.5:1 and times greater than MIC exceeded 35 h. From in vitro time-kill curves, PK/PD modelling established serum breakpoint values for the index AUC24h/MIC for three levels of inhibition of growth, bacteriostasis and 3 and 4log10 reductions in bacterial count; means were 25.7, 40.2 and 47.0 h, respectively, for P. multocida and 24.6,
Periodontitis is mankinds most common chronic inflammatory disease. One severe form of periodontitis is localized aggressive periodontitis (LAP), a condition to which individuals of African origin demonstrate an increased susceptibility. The main causative organism of this disease is Actinobacillus …
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SWISS-MODEL Repository entry for B3H073 (YQGF_ACTP7), Putative pre-16S rRNA nuclease. Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
SWISS-MODEL Repository entry for B3GZ69 (KTHY_ACTP7), Thymidylate kinase. Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Complete article is available online.. PDF version is available online.. Objective: To evaluate the duration of efficacy of a single dose of ceftiofur crystalline free acid sterile suspension (CCFA-SS) against clinical disease in grower pigs inoculated intratracheally with Actinobacillus pleuropneumoniae.. Materials and methods: One hundred and ninety male piglets were blocked by weight and randomly assigned to 19 pens of 10 animals each, with three pens randomly assigned to each of six treatments. Pigs were challenged with A pleuropneumoniae at 7 to 8 weeks old (Day 0). Groups 1 through 5 were treated with a single intramuscular dose of CCFA-SS (5 mg ceftiofur equivalents per kg body weight) on Days -13, -10, -7, -4, and -1, respectively. Group 6 pigs were challenged, untreated controls. A single pen of 10 unchallenged, untreated pigs acted as sentinels. The primary variable was removal rate (percent of pigs per pen that died or were euthanized because of severe illness by Day 9). Ancillary ...
Actinobacillus equulis: especie que se encuentra en la cavidad bucal y amígdalas del caballo y causa lesiones supurativas de los riñones y articulaciones de los cerdos y caballos y endocarditis en el cerdo ...
Biohazard level, growth media and temperature, gram stain, industrial applications and more information for Actinobacillus hominis.
Pourquier, P., Lesceu, S. Use of the ID Screen® APP indirect ELISA range for quick identification and serotyping of Actinobacillus pleuropneumoniae in domestic pigs. Poster presented at the 6th International Symposium on Emerging and Re-emerging Pig Diseases, June 2011, Madrid, Spain ...
Formulated to provide outstanding protection against the most common and virulent serotypes 1, 5 and 7. For prevention of pneumonia in pigs 4 weeks of age or older by infection with the prevalent serotypes of Actinobacillus pleuropneumoniae ...
With funding from Pork CRC, Australian scientists have developed a new one-shot vaccine delivery system against the endemic pig disease Actinobacillus pleuropneumoniae (APP).
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Investigation of the structure of lipid A from Actinobacillus actinomycetemcomitans strain Y 4 and human clinical isolate PO 1021-7
Actinobacillus pleuropneumoniae is the etiologic agent of porcine contagious pleuropneumonia, a significant disease that causes serious economic losses to the swine industry worldwide. Persistent infections caused by bacterial biofilms are recalcitrant to treat because of the particular drug resistance of biofilm-dwelling cells. TolC, a key component of multidrug efflux pumps, are responsible for multidrug resistance in many Gram-negative bacteria. In this study, we identified two TolC-like proteins, TolC1 and TolC2, in A. pleuropneumoniae. Deletion of tolC1, but not tolC2, caused a significant reduction in biofilm formation, as well as increased drug sensitivity of both planktonic and biofilm cells. The genetic-complementation of the tolC1 mutation restored the competent biofilm and drug resistance. Besides, biofilm formation was inhibited and drug sensitivity was increased by the addition of phenylalanine-arginine beta-naphthylamide (PAβN), a well-known efflux pump inhibitor (EPI), suggesting a role
Porcine pleuropneumonia, caused by Actinobacillus pleuropneumoniae, is a bacterial respiratory disease of swine. Acute outbreaks of the disease are often accompanied by high mortality and economic losses. As severe cases of the disease frequently require parenteral antibiotic treatment of the animals, the efficacy of a single, high dose of marbofloxacin was compared to a three-time application of a dose of enrofloxacin under experimental conditions. A blinded, controlled, randomized and blocked dose confirmation study was conducted to test the efficacy and safety of a single dose of 8 mg/kg marbofloxacin (160 mg/ml, Forcyl® Swine, Vetoquinol SA, France) to treat acute porcine pleuropneumonia after experimental aerosol inoculation of pigs with A. pleuropneumoniae serotype 2. The results were compared to a three consecutive day treatment of 2.5 mg/kg enrofloxacin and a mock (saline) treatment. Criteria for the assessment of efficacy were severity of lung lesions, bacteriological cure and the course of
TY - JOUR. T1 - Cell surface-associated enolase in Actinobacillus actinomycetemcomitans. AU - Hara, Hiroaki. AU - Ohta, Hiroyuki. AU - Inoue, Tetsuyoshi. AU - Ohashi, Toshio. AU - Takashiba, Shogo. AU - Murayama, Yoji. AU - Fukui, Kazuhiro. PY - 2000. Y1 - 2000. N2 - Cell surface-associated materials of Actinobacillus actinomycetemcomitans were extracted by a short incubation of the cell suspension in a Tris-buffered saline in the presence and absence of a restriction enzyme, EcoRI. The supernatants (which we termed EcoRI extract and surface extract, respectively) contained a number of extracellularly released proteins. Of these proteins, four major proteins were identified by N-terminal sequencing to be the 34 and 39 kDa outer membrane proteins, the GroEL-like protein, and a 47 kDa protein homologous to Haemophilus influenzae enolase. Enolase activity was found in the extracts and its relative amount of activity in the EcoRI extract from a culture of the mid-exponential growth phase was ...
Two previous studies have observed natural transformation in A. actinomycetemcomitans. Tøonjum et al. (30) used a broth-based method and identified two naturally competent strains among five study strains of A. actinomycetemcomitans with transformation frequencies of 1.3 × 10−3 and 6.2 × 10−5. In our present study, we identified a single highly competent A. actinomycetemcomitans strain among 17 strains examined. Although this is an apparently lower prevalence of naturally competent A. actinomycetemcomitans strains than was reported by Tøonjum et al., the transformation frequencies reported in this study were similar.. Sato et al. (23) generated transposon insertional mutants from the A. actinomycetemcomitans strain Y4 by natural transformation. The transformation was performed with broth-cultured exponential-phase A. actinomycetemcomitans cells. However, strain Y4 was not transformable in our study. While the loss of competence is sometimes a consequence of laboratory propagation, it is ...
0165] (1) Wilson M, Henderson, B. Virulence factors of A. actinomycetemcomitans revenant to the pathogenesis of inflammatory periodontal diseases. FEMS 1995:17:365-379. [0166] (2) Nowotny A, Behling U H, Hammond B, et al. Release of toxic microvesicles by Actinobacillus actinomycetemcomitans. Infect Immun 1982:37:151-154. [0167] (3) Kaplan J B, Perry M B, MacLean L L, Furgang D, Wilson M E, Fine D H. Structural and genetic analyses of 0 polysaccharide from Actinobacillus actinomycetemcomitans serotype f. Infect Immun 2001:69:5375-5384. [0168] (4) Rosan B, Slots J, Lamont R J, Listgarten M A, Nelson G M. Actinobacillus actinomycetemcomitans fimbriae. Oral Microbiol Immunol 1988:3:58-63. [0169] (5) Inouye T, Ohta H, Kokeguchi S, Fukui K, Kato K. Colonial variation and fimbriation of Actinobacillus actinomycetemcomitans. FEMS microbiology letters 1990: 57: 13-17. [0170] (6) Kaplan J B, Schreiner H C, Furgang D, Fine D H. Population structure and genetic diversity of Actinobacillus ...
A little over two years ago, we commented on a general rise in the frequency of Actinobacillus suis (A. suis) isolation from our swine tissue submission cases, and wondered if it was related to the increased porcine circovirus type 2 (PCV2) activity (National Hog Farmer North American Preview, June 6, 2008).
Structures of the antigenic O-polysaccharides of lipopolysaccharides produced by Actinobacillus actinomycetemcomitans serotypes a, c, d and e
The complete nucleotide sequence of a 7.7kb mobilisable plasmid (pM3446F), isolated from a florfenicol resistant isolate of Actinobacillus pleuropneumoniae, showed extended similarity to plasmids found in other members of the Pasteurellaceae containing the floR gene as well as replication and mobilisation genes. Mobilisation into other Pasteurellaceae species confirmed that this plasmid can be transferred horizontally ...
Fingerprint Dive into the research topics of Isolation and characterization of the dnaKJ operon from Actinobacillus actinomycetemcomitans. Together they form a unique fingerprint. ...
ID C9R3L9_AGGAD Unreviewed; 404 AA. AC C9R3L9; DT 24-NOV-2009, integrated into UniProtKB/TrEMBL. DT 24-NOV-2009, sequence version 1. DT 25-OCT-2017, entry version 39. DE SubName: Full=Molybdopterin molybdenumtransferase {ECO:0000313,EMBL:ACX82405.1}; GN OrderedLocusNames=D11S_1018 {ECO:0000313,EMBL:ACX82405.1}; OS Aggregatibacter actinomycetemcomitans serotype C (strain D11S-1) OS (Actinobacillus actinomycetemcomitans). OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; OC Pasteurellaceae; Aggregatibacter. OX NCBI_TaxID=668336 {ECO:0000313,EMBL:ACX82405.1, ECO:0000313,Proteomes:UP000002569}; RN [1] {ECO:0000313,EMBL:ACX82405.1, ECO:0000313,Proteomes:UP000002569} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=D11S-1 {ECO:0000313,EMBL:ACX82405.1, RC ECO:0000313,Proteomes:UP000002569}; RX PubMed=19820097; DOI=10.1128/JB.01203-09; RA Chen C., Kittichotirat W., Si Y., Bumgarner R.; RT Genome sequence of Aggregatibacter actinomycetemcomitans serotype c RT strain D11S-1.; ...
Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR ...
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Astăzi, conform manualului Bergey, în genul Actinobacillus, în afară de A. lignieresii şi A. suis, care produc bolile numite actinobaciloze, sunt alăturate şi alte 16 specii de bacterii (1). Acestea însă fie că produc entităţi diferite ca patogenie şi manifestări anatomoclinice, din care cauză poartă şi denumiri diferite, fie că produc nişte infecţii, în general rare, localizate şi manifestate altfel decât boala limbii de lemn produsă de A.lignieresii, fie că sunt prezente ca simpli germeni oportunişti, fără un rol patologic bine precizat. Dintre acestea, patologia veterinară este interesată de:. - A.pleuropneumoniae, care produce pleuropneumonia infecţioasă a porcului, ...
Monoclonal antibody against Aggregatibacter actinomycetemcomitans serotype b expressed by for use in Western Blot against gram-negative bacteria
LIU, Qiong et al. Construction and immunogenicity of a ΔapxIC/ompP2 mutant of Actinobacillus pleuropneumonias and Haemophilus parasuis. Onderstepoort j. vet. res. [online]. 2013, vol.80, n.1, pp.1-6. ISSN 2219-0635.. The apxIC genes of the Actinobacillus pleuropneumoniae serovar 5 (SC-1), encoding the ApxI-activating proteins, was deleted by a method involving sucrose counter-selection. In this study, a mutant strain of A. pleuropneumoniae (SC-1) was constructed and named AapxIC/ ompP2. The mutant strain contained foreign DNA in the deletion site of ompP2 gene of Haemophilus parasuis. It showed no haemolytic activity and lower virulence of cytotoxicity in mice compared with the parent strain, and its safety and immunogenicity were also evaluated in mice. The LD50 data shown that the mutant strain was attenuated 30-fold, compared with the parent strain (LD50 of the mutant strain and parent strain in mice were determined to be 1.0 x 107 CFU and 3.5 x 105 CFU respectively). The mutant strain that ...
TY - JOUR. T1 - Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages in humans.. AU - Nakagawa, S.. AU - Machida, Y.. AU - Nakagawa, Taneaki. AU - Fujii, H.. AU - Yamada, S.. AU - Takazoe, I.. AU - Okuda, K.. PY - 1994/1. Y1 - 1994/1. N2 - This study examined the serum IgG and IgM responses against Porphyromonas gingivalis and 3 serotypes of Actinobacillus actinomycetemcomitans, and the correlations of these responses with age and homologous infection. A total of 90 individuals were included in this study: 40 subjects with gingivitis, 40 periodontally healthy subjects, and 10 adult periodontitis subjects. The subjects in the gingivitis and periodontally healthy groups were divided into 4 stages based on their physiological age: early childhood, school age, puberty, and adult. In the gingivitis group, there was a positive correlation between increase in age and increase in serum IgG antibody levels against P. gingivalis until ...
Aggregatibacter (Actinobacillus) actinomycetemcomitans is a bacterium mainly associated with aggressive forms of periodontitis. Among its virulence factors, a leukotoxin is suggested to play an important role in the pathogenicity. Periodontal infections with strains producing high levels of the leukotoxin are strongly associated with severe disease. Leukotoxin selectively kills human leukocytes and can disrupt the local defense mechanisms. Previous studies examining the role of the leukotoxin in host-parasite interactions have mainly focused on polymorphonuclear leukocytes (PMNs). In the inflamed periodontium, macrophages play a significant role in the regulation of the inflammatory reactions and the tissue breakdown and remodeling.. Thus, the aim of this dissertation was to investigate death mechanisms of human macrophages exposed to leukotoxin.. Human lymphocytes, PMNs, and monocytes/macrophages isolated from venous blood were exposed to purified leukotoxin or live A. actinomycetemcomitans ...
Aggregatibacter actinomycetemcomitans ATCC ® 700685D-5™ Designation: Genomic DNA from Aggregatibacter actinomycetemcomitans strain HK1651 TypeStrain=False Application:
Structural studies of the O-chain of the phenol-phase soluble lipopolysaccharide from Haemophilus pleuropneumoniae serotype 2: Biochem.Cell Biol.
Aggregatibacter actinomycetemcomitans (A.a) serotypes may add some important information of the pathogenetic background of periodontal infections. (adsbygoogle = window.adsbygoogle ,, []).push({}); When grown in culture, these form small colonies, approximately 0.5-1.0 mm in diameter. The cytotoxin produced by, Almost all strains of A. actinomycetemcomitans have these vesicles. 2008 Apr 1;10(5):489-96. The results of the study showed that these antibodies might contribute to limit the systemic effects of the infection. Ltx B and Ltx D are involved in transporting the toxin to the surface of the cell while Ltx C post-transitionally activates the toxin. The most common bacteria involved in periodontal pathologies of young individuals and in cases of refractory adult periodontitis is Aggregatibacter actinomycetemcomitans. This genus includes Gram-negative, non-motile, facultatively anaerobic rods or coccobacilli that were previously known as Haemophilus. The active subunit, CdtB, exhibits DNase I ...
TY - GEN. T1 - Experimental and modelling studies of the bioconversion of glycerol to succinic acid by actinobacillus succinogenes. AU - Vlysidis, Anestis. AU - Du, Chenyu. AU - Webb, Colin. AU - Theodoropoulos, Constantinos. PY - 2008/12/1. Y1 - 2008/12/1. N2 - An unstructured kinetic model for the growth of Actinobacillus succinogenes on glycerol as the only carbon source is proposed in this study. The model describes cell growth considering both substrate and product inhibition. and its parameters are estimated by fitting the model predictions to experimental data. Substrate consumption and product formation rates are described by the Luedeking-Piret model. The main product of the process is succinic acid while by-products like acetate, formate and ethanol have very low concentrations. The main environmental factors that affect the bioprocess were examined and optimum conditions in terms of yield, final succinic acid concentration and productivity were evaluated by a factorial experimental ...
Succinic acid (SA) is poised to become a significant building-block or platform chemical in the bio-based economy. Of the microbial strains that show promise for biological SA production, the wild-type bacterium Actinobacillus succinogenes is one of the top-contenders. While strides have been made towards understanding the behaviour of the organism and developing the fundamentals for an industrial process based on the organism, there is still a large scope of research required and a multitude of challenges to be addressed. In particular, an improved understanding of the metabolism of the organism under favourable biofilm conditions is required and its potential as a microbial host in a biorefinery setting needs to be established. Therefore, the aim of this thesis is to develop a fundamental understanding of the central metabolism of the organism under biofilm conditions on relevant substrates, and to determine its performance as a SA producer on scalable biorefinery streams. Continuous operation ...
TY - JOUR. T1 - Towards an understanding of equine pleuropneumonia. T2 - Factors relevant for control. AU - Racklyeft, D. J.. AU - Raidal, S.. AU - Love, D. N.. PY - 2000/5. Y1 - 2000/5. N2 - Objective: To review relevant literature on factors associated with the development of equine pleuropneumonia Design: A review of the literature using a range of databases including Current Contents, Medline, ChemAbstracts, Biological Abstracts and CAB and a comprehensive search strategy which involved use of keywords, author and subject category searches. Additional sources included review of articles cited by key accumulated references. Results: Since the early years of this century, many of the gaps in our knowledge of the pathogenesis of this disease have been filled. We now know that equine pleuropneumonia results from contamination of the lower respiratory tract with bacteria similar to the normal oropharyngeal microbiota of the horse and that transportation of any mode, especially over long ...
This study evaluated the effect of oral lactobacilli on the cytotoxicity and cytokine release from peripheral blood mononuclear cells (PBMCs) when exposed to Aggregatibacter actinomycetemcomitans subtypes in vitro. The supernatants and cell wall extracts (CWEs) of eight A. actinomycetemcomitans strains, representing different subtypes, and three Lactobacillus strains were used. The PBMCs from six blood donors were exposed to supernatants and CWEs of A. actinomycetemcomitans or Lactobacillus strains alone or combinations and untreated cells as control. The cytotoxicity was determined by trypan blue exclusion method and IL-1β secretion by ELISA. TNF-α, IL-6, and IL-8 secretions were measured using Bioplex Multiplex Immunoassay. Supernatants or CWEs from all bacterial strains showed cytotoxicity and IL-1β secretion and the subtypes of A. actinomycetemcomitans showed generally a significantly higher effect on PBMCs than that of the Lactobacillus strains. Two highly toxic A. actinomycetemcomitans strains
The ability to selectively target specific biofilm species with antimicrobials would enable control over biofilm consortium composition, with medical applications in treatment of infections on mucosal surfaces that are colonized by a mixture of beneficial and pathogenic microorganisms. We functionalized a genetically engineered multimeric protein with both a targeting moiety (biotin) and either a fluorophore or a photosensitizer (SnCe6). Biofilm microcolonies of Aggregatibacter actinomycetemcomitans, a periodontal pathogen, were targeted with the multifunctional dodecamer. Streptavidin was used to couple biotinylated dodecamer to a biotinylated anti-A. actinomycetemcomitans antibody. This modular targeting approach enabled us to increase the loading of photosensitizer onto the cells by a cycle of amplification. Scanning laser confocal microscopy was used to characterize transport of fluorescently tagged dodecamer into the microcolonies and targeting of the cells with biotin-labeled, ...
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Adolescent; Aggregatibacter actinomycetemcomitans; Bacterial Toxins; Cohort Studies; Cross-Sectional Studies; DNA, Bacterial; Disease Progression; Ghana; Humans; Pasteurellaceae Infections; Periodontal Diseases ...
Aggregatibacter actinomycetemcomitans GroEL Protein Promotes Conversion of Human CD4 T Cells into IFNγ IL10 Producing Tbet Th1 Cells. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Importance of Streptococci in the reproduction disorders OF THE MARE. NEW DATAS. The authors described the important intervention of Strepto coccus zooepidemicus, equi, equisimilis and uberis in the bacterial disorders of reproduction (fertility, endometritis) and causes of abortion. The principal bacterial pathogens causing disorders are : Streptococci, Escherichia coli, Klebsiella pneumoniae, Actinobacillus equuli, Salmonella typhimurium, Pseudomonas aeruginosa. The Streptococcal diseases are found in over 50 per cent of confirmed cases of bacterial disorders of reproduction. The bacterial contamination access to the vagina and uterus of the mares, often, during the breeding of foaling. The bacteriological controls of mares and stallions are necessary before breeding and the research of several bacterial organisms is obligatory ...
Learn about the veterinary topic of Pleuropneumonia in Horses. Find specific details on this topic and related topics from the Merck Vet Manual.
TSBV agar is an enriched selective medium used for the isolation of Aggregatibacter actinomycetemcomitans from clinical specimens. The nutritive base consists of casein, soy peptone, and yeast extract. Sodium chloride is added to maintain osmotic equilibrium of the media. Serum is included to enhance the recovery of Aggregatibacter actinomycetemcomitans. The selective agents include bacitracin and vancomycin at concentrations that inhibit most gram-positive and gram-negative anaerobes. This media is prepared, dispensed, and packaged under oxygen-free conditions to prevent the formation of oxidized products prior to use.. ...
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A Periodontite Agressiva (PA), que atualmente pertence ao grupo das Periodontites est gios 3 e 4, distingue-se dos demais tipos de doen a periodontal por seu in cio precoce, agrega o familiar dos casos e por afetar pacientes sistemicamente saud veis. Al m disso, pode ser subclassificada em duas formas, localizada (PAL) e generalizada (PAG), em fun o de sua extens o. Muitas vezes, os dep sitos de biofilme bacteriano s o desproporcionais quantidade de destrui o ssea e perda de inser o que o paciente apresenta, independente da subclassifica o. O microrganismo mais relacionado etiopatog nese da doen a o Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans), incluindo os seus principais sorotipos a, b e c, amplamente estudados. Associado a estas condi es, A. actinomycetemcomitans apresenta alguns fatores de virul ncia como uma leucotoxina, principalmente ligada ao sorotipo b - clone JP2 (que altamente leucot xico) e prote nas de membrana externa (OMPs), especialmente Omp29. A resposta de ...
Immunological detection of antigens of Aggregatibacter actinomycetemcomitans, P intermedia, P gingivalisusing antibodies (ELISA ...
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Actinobacillus pleuropneumonia and Salmonella infections in pigs. Prior to the introduction of vaccination with material from ... "Development of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae infection". Vaccine. 24 (49-50): 7226-7237. doi: ... Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or ... If a vaccinated individual does develop the disease vaccinated against (breakthrough infection), the disease is likely to be ...
"Development of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae infection". Vaccine. 24 (49-50): 7226-37. doi: ... Lack of response commonly results from clinical factors such as diabetes, steroid use, HIV infection, or age.[citation needed] ... 19 July 2017 Vaccines promoted as key to stamping out drug-resistant microbes "Immunization can stop resistant infections ... Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or ...
"Development of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae infection". Vaccine. 24 (49-50): 7226-37. doi: ... "19 July 2017 Vaccines promoted as key to stamping out drug-resistant microbes "Immunization can stop resistant infections ... Robinson HL, Pertmer TM (2000). DNA vaccines for viral infections: basic studies and applications. Advances in Virus Research. ... Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or ...
Overcrowding in pigpens, co-infections of other respiratory pathogens, and unusual stress all contribute to the spread of the ... "Actinobacillus pleuropneumoniae". Iowa State University College of Veterinary Medicine. Retrieved 3 September 2018. Shope, RE ( ... Gillaspy, A. "Actinobacillus pleuropneumoniae". Laboratory for Molecular Biology and Cytometry Research-University of Oklahoma ... In 1995, A. pleuropneumoniae infections cost the US economy about $30 million. Such losses usually result from medication and ...
Affected piglets can develop septicaemia, multifocal infections, respiratory signs, and may die. Adult pigs may show signs ... Actinobacillus suis is a beta-haemolytic, Gram-negative bacterium of the family Pasteurellaceae. The bacterium has many strains ... Type strain of Actinobacillus suis at BacDive - the Bacterial Diversity Metadatabase. ... Signs and necropsy findings may mimic diseases such as: Erysipelas, Glasser's Disease, Streptococcus suis and Actinobacillus ...
"EHV-1 Congenital Infection and Concurrent Actinobacillus Equuli Septicemia in a Standardbred Neonatal Foal: Clinical, ... "Facial Cellulitis Due to Actinobacillus Equuli Infection in a Neonatal Foal." Veterinary Record 162.11 (2008): 347-349. Web. ... "Septicemia and Peritonitis Due to Actinobacillus Equuli Infection in an Adult Horse." Veterinary Pathology 38.2 (2001): 230-232 ... Infections in swine are more common in European countries compared to the North American Countries. Infections in the United ...
All infections were cured. Intervet developed cefquinome (Cobactan) to treat bovine respiratory disease, the most common ... Actinobacillus pleuropneumoniae, and Streptococcus suis. Mastitis-metritis-agalactia syndrome involved with E. coli, ... For pigs, it is used to treat bacterial infections of the lungs and respiratory tract caused by P. multocida, Haemophilus ... To prevent the claimed infections in piglets, attention should be paid to hygiene and ventilation, and overcrowding should be ...
This infection-related cutaneous condition article is a stub. You can help Wikipedia by expanding it.. *v ... Chromobacteriosis infections are a cutaneous condition caused by chromobacteria characterized by fluctuating abscesses.[1]:279 ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Chromobacteriosis_infection&oldid=910443079" ...
Kidney infection, if it occurs, usually follows a bladder infection but may also result from a blood-borne infection.[12] ... A urinary tract infection (UTI) is an infection that affects part of the urinary tract.[1] When it affects the lower urinary ... Urinary tract infections are the most frequent bacterial infection in women.[17] They occur most frequently between the ages of ... Lower urinary tract infection is also referred to as a bladder infection. The most common symptoms are burning with urination ...
Sneath, P. H. A.; Stevens, M. (1990). "Actinobacillus rossii sp. nov., Actinobacillus seminis sp. nov., nom. rev., Pasteurella ... Pasteurella bettyae is a bacterium associated with human Bartholin gland abscess and finger infections. ...
In addition to valvular infections in the heart, they can also produce other infections such as bacteremia, abscess, ... HACEK originally referred to Haemophilus parainfluenzae, Haemophilus aphrophilus, Actinobacillus actinomycetemcomitans, ... which is an inflammation of the heart due to bacterial infection. HACEK is an abbreviation of the initials of the genera of ... and share an enhanced capacity to produce endocardial infections, especially in young children. Collectively they account for 5 ...
It has also been isolated from actinomycotic lesions (mixed infection with certain Actinomyces species, in particular A. ... Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans) is a Gram-negative, facultative ... Jorth P, Trivedi U, Rumbaugh K, Whiteley M (November 2013). "Probing bacterial metabolism during infection using high- ... Less frequently, A. actinomycetemcomitans is associated with nonoral infections such as endocarditis. Its role in aggressive ...
Polyps or mucus can obstruct the nasopharynx, as can congestion due to an upper respiratory infection. The auditory tube, which ... The HACEK organisms (Haemophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, Kingella ... and share an enhanced capacity to produce endocardial infections, especially in young children. Fusobacterium is a pathogen. ...
Fives-Taylor PM, Meyer DH, Mintz KP, Brissette C (June 1999). "Virulence factors of Actinobacillus actinomycetemcomitans". ... Clinical Microbiology and Infection. 7 (4): 213-7. doi:10.1046/j.1469-0691.2001.00210.x. PMID 11422244. Genco RJ, Zambon JJ, ... Zambon JJ, Christersson LA, Slots J (December 1983). "Actinobacillus actinomycetemcomitans in human periodontal disease. ... High levels of Aggregatibacter (or Actinobacillus) actinomycetemcomitans and, in some populations, Porphyromonas gingivalis. ...
"Comparison of Two Selective Media for Actinobacillus actinomycetemcomitans." J Clin Microbiol 1986;24:636-638. Fryman A, ... that substantiated aggressive periodontitis as a bona fide infection, rather than merely a degenerative disorder. Dental ... Slots is responsible for discovering the role of Aggregatibacter actinomycetemcomitans (previously Actinobacillus ...
... actinobacillus infections MeSH C01.252.400.700.030.178 - actinobacillosis MeSH C01.252.400.700.433 - haemophilus infections ... bacteroides infections MeSH C01.252.400.126 - bartonellaceae infections MeSH C01.252.400.126.100 - bartonella infections MeSH ... moraxellaceae infections MeSH C01.252.400.560.022 - acinetobacter infections MeSH C01.252.400.610 - mycoplasmatales infections ... salmonella infections, animal MeSH C01.252.400.310.821.873 - typhoid fever MeSH C01.252.400.310.850 - serratia infections MeSH ...
... of people with gonorrheal infection also have chlamydial infection.[54] Infections of the throat can be especially problematic ... Both men and women with infections of the throat may experience a sore throat, though such infection does not produce symptoms ... The infection is usually spread from one person to another through vaginal, oral, or anal sex.[15][22] Men have a 20% risk of ... "Gonococcal Infections - 2015 STD Treatment Guidelines". 4 January 2018.. *^ Ryan, KJ; Ray, CG, eds. (2004). Sherris Medical ...
... may be useful for treating and preventing biofilm-associated infections caused by poly-N-acetylglucosamine- ... Kaplan JB, Ragunath C, Ramasubbu N, Fine DH (August 2003). "Detachment of Actinobacillus actinomycetemcomitans biofilm cells by ... Kaplan JB, Meyenhofer MF, Fine DH (2003). "Biofilm growth and detachment of Actinobacillus actinomycetemcomitans". J. Bacteriol ... a biofilm-releasing glycoside hydrolase from the periodontopathogen Actinobacillus actinomycetemcomitans". J. Mol. Biol. 349 (3 ...
Infection has been shown to have high prevalence in the autumn and winter months. K.kingae infections are rare in adults, but ... Actinobacillus, Cardiobacterium, Eikenella, and Kingella organisms: a retrospective multicenter evaluation". J. Clin. Microbiol ... Poor oral hygiene, pharyngitis, and mucosal ulceration are also predisposing factors for infection. The infection can occur in ... The infection rate is poorly documented, thus the illness tends to go underdiagnosed. K. kingae can be transmitted person to ...
With the consistent and complete removal of biofilm, the infection can be arrested and healthy periodontium can be achieved. ... These bacteria include Porphyromonas gingivalis, Prevotella intermedia, and Actinobacillus actinomycetemcomitans. Healthy ...
... viral infection, and bacterial infection. As a result, sulfatide is associated with, able to bind to, and/or is present in ... Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae are pathogens that cause respiratory disease in swine. Haemophilus ... However, sulfatide has little function in HIV-1 infection of CD4+ cells. The binding of gp120 to GalCer has the ability to ... Sulfatide has been shown to play a role or have some association with several diseases and infections. This includes diabetes ...
"First description of an Anaerobiospirillum succiniciproducens prosthetic joint infection". New Microbes and New Infections. 18 ... Henderson B, Ward JM, Ready D (October 2010). "Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* ... It can be potentially lethal to humans, but infections are rare. Cyrtodactylus australotitiwangsaensis Grismer et al., 2012 - ... Norskov-Lauritsen N, Kilian M (2006). "Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, ...
... urinary tract infections, catheter infections, middle-ear infections, formation of dental plaque, gingivitis, coating contact ... Kaplan JB, Ragunath C, Ramasubbu N, Fine DH (August 2003). "Detachment of Actinobacillus actinomycetemcomitans biofilm cells by ... Examples of such infections include chronic wounds, chronic otitis media, chronic prostatitis and chronic lung infections in ... Biofilms of fungal origin are important aspects of human infection and fungal pathogenicity, as the fungal infection is more ...
The question then became how exposure to the caterpillars produced these non-specific bacterial infections of the affected ... Actinobacillus encephalitis. MRLS was observed in mares of all breeds and ages. Early and late fetal losses were observed ... Mares which aborted are treated with broad-spectrum antibiotics to avoid bacterial infections. The foals born from mares ... Reviewing the speed with which ETCs produced late-term abortions in 2002 experiments, the nonspecific bacterial infections in ...
Adequate plaque control is important in ensuring long-term results from the procedure, and if post-operative infection control ... CO2 laser Diode laser It has been suggested that lasers can give a substantial reduction in bacteria such as Actinobacillus ...
John TJ, Cherian T, Steinhoff MC, Simoes EA, John M (1991). "Etiology of acute respiratory infections in children in tropical ... Tri gjinitë më të rëndësishme të familjes Pasteurellaceae janë haemophilus, actinobacillus, dhe pasteurella. Pjesëtarët e kësaj ...
... are a class of gram-negative bacteria, and one of the eight classes of the phylum Proteobacteria.[1] The Betaproteobacteria are a class comprising over 75 genera and 400 species of bacteria.[2] Together, the Betaproteobacteria represent a broad variety of metabolic strategies and occupy diverse environments from obligate pathogens living within host organisms to oligotrophic groundwater ecosystems. Whilst most members of the Betaproteobacteria are heterotrophic, deriving both their carbon and electrons from organocarbon sources, some are photoheterotrophic, deriving energy from light and carbon from organocarbon sources. Other genera are autotrophic, deriving their carbon from bicarbonate or carbon dioxide and their electrons from reduced inorganic ions such as nitrite, ammonium, thiosulfate or sulfide [1] - many of these chemolithoautotrophic Betaproteobacteria are economically important, with roles in maintaining soil pH and in elementary cycling. Other economically ...
... is a large family of Gram-negative bacteria. It was first proposed by Rahn in 1936, and now includes over 30 genera and more than 100 species. Its classification above the level of family is still a subject of debate, but one classification places it in the order Enterobacterales of the class Gammaproteobacteria in the phylum Proteobacteria.[2][3][4][5] Enterobacteriaceae includes, along with many harmless symbionts, many of the more familiar pathogens, such as Salmonella, Escherichia coli, Klebsiella, and Shigella. Other disease-causing bacteria in this family include Enterobacter and Citrobacter. Members of the Enterobacteriaceae can be trivially referred to as enterobacteria or "enteric bacteria",[6] as several members live in the intestines of animals. In fact, the etymology of the family is enterobacterium with the suffix to designate a family (aceae)-not after the genus Enterobacter (which would be "Enterobacteraceae")-and the type genus is Escherichia. ...
"Infections in Medicine.. (subscription required) *^ Health Protection Agency Meningococcus Forum (August 2006). "Guidance for ... 16 in Hendrik K.F, Van Saene H.K.F., Silvestri L. y Cal M.A. (eds.), Infection Control in the Intensive Care Unit,, Springer ... Current guidance in the United Kingdom is that if a case of meningococcal meningitis or septicaemia (infection of the blood) is ... In susceptible individuals, N. meningitidis may invade the bloodstream and cause a systemic infection, sepsis, disseminated ...
... of people with gonorrheal infection also have chlamydial infection.[54] Infections of the throat can be especially problematic ... Both men and women with infections of the throat may experience a sore throat, though such infection does not produce symptoms ... The infection is usually spread from one person to another through vaginal, oral, or anal sex.[15][22] Men have a 20% risk of ... "Gonococcal Infections - 2015 STD Treatment Guidelines". 4 January 2018.. *^ Ryan, KJ; Ray, CG, eds. (2004). Sherris Medical ...
... is an infection of the small intestine by some strains of the bacterium Vibrio cholerae.[4][3] Symptoms may range from ... "The Journal of Infection. 66 (5): 432-8. doi:10.1016/j.jinf.2012.11.013. PMC 3677557. PMID 23201968.. ... Infection with V. cholerae O139 should be reported and handled in the same manner as that caused by V. cholerae O1. The ... Cholera - Vibrio cholerae infection-Centers for Disease Control and Prevention. *‹See Tfd›. "Cholera" . Encyclopædia Britannica ...
If the infection is severe, the doctor may prescribe antibiotics, such as ciprofloxacin or TMP-SMX (Bactrim). Unfortunately, ... In addition, chronic arthritis secondary to S. flexneri infection, called reactive arthritis, may be caused by a bacterial ... Bacillary dysentery should not be confused with diarrhea caused by other bacterial infections. One characteristic of bacillary ... human enteric infections". Vaccine. 24 (15): 2732-50. doi:10.1016/j.vaccine.2005.10.014. PMID 16483695.. ...
Rickettsia aeschlimannii infection) ... Pasteurella multocida (Pasteurellosis) · Actinobacillus ( ...
... (TD) is a stomach and intestinal infection. TD is defined as the passage of unformed stool (one or more by ... The primary source of infection is ingestion of fecally contaminated food or water. Attack rates are similar for men and women. ... Antibiotics can also cause vaginal yeast infections, or overgrowth of the bacterium Clostridium difficile, leading to ... Since wilderness campsites seldom provide access to sanitation facilities, the infection risk is similar to that of any ...
Salih, Barik (June 2007). "H pylori infection and other risk factors associated with peptic ulcers in Turkish patients: A ... 2002). "Long-term stress and Helicobacter pylori infection independently induce gastric mucosal lesions in C57BL/6 mice". Scand ... "Monotherapy with mastic does not eradicate Helicobacter pylori infection from mice". J. Antimicrob. Chemother. 51 (2): 367-71 ...
Infections à méningocoques Maladies infectieuses et Africa. West Africa. Med. Bull. 2007[unreliable source?] ... Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis (also termed meningococcus). It has a ... Meningococcal infection is usually introduced into a household by an asymptomatic person. Carriage then spreads through the ... meningitidis infection than complement-satisfactory persons,[27][28][29][30][31][32][33] and it was estimated that the risk of ...
Confirmation of infection can be done by examining serum taken during the early and late stages of infection. To quickly screen ... The three types of plague are the result of the route of infection: bubonic plague, septicemic plague, and pneumonic plague.[1] ... 14] With no new rat inputs being added to the population from other areas, the infection would only spread to humans in very ... Bubonic plague is an infection of the lymphatic system, usually resulting from the bite of an infected flea, Xenopsylla cheopis ...
Human papillomavirus (HPV) infection One of the Human papillomaviruses Human parainfluenza virus infection Human parainfluenza ... Infections associated with diseases. References[edit]. *^ Walsh TJ, Dixon DM (1996). Baron S, et al., eds. Spectrum of Mycoses ... Acinetobacter infections Acinetobacter baumannii Actinomycosis Actinomyces israelii, Actinomyces gerencseriae and ... Haemophilus influenzae infection Haemophilus influenzae Hand, foot and mouth disease (HFMD) Enteroviruses, mainly Coxsackie A ...
Rickettsia aeschlimannii infection) ... Pasteurella multocida (Pasteurellosis) · Actinobacillus( ...
Trematode infection). Blood fluke. *Schistosoma mansoni / S. japonicum / S. mekongi / S. haematobium / S. intercalatum * ... Tapeworm - Tapeworm infection Cestoda, Taenia multiceps intestine stool rare worldwide Diphyllobothriasis - tapeworm ... Dioctophyme renalis infection Dioctophyme renale kidneys (typically the right) urine rare ingestion of undercooked or raw ... sexually transmitted infection - only trophozoite form (no cysts) Sleeping sickness Trypanosoma brucei brain and blood ...
K. aerogenes is a nosocomial and pathogenic bacterium that causes opportunistic infections including most types of infections. ... Some of the infections caused by K. aerogenes result from specific antibiotic treatments, venous catheter insertions, and/or ...
IgM shows recent infection whereas IgG signifies remote infection. The most important limitation of this test is that it is not ... Typhoid fever, also known simply as typhoid, is a bacterial infection due to Salmonella typhi that causes symptoms.[3] Symptoms ... The typhidot test becomes positive within 2-3 days of infection and separately identifies IgM and IgG antibodies. The test is ... Cholecystectomy is not always successful in eradicating the carrier state because of persisting hepatic infection. ...
... pylori infection, it does not seem to independently increase risk. Even when coupled with H. pylori infection, the increase is ... In Western countries, the percentage of people with H. pylori infections roughly matches age (i.e., 20% at age 20, 30% at age ... This campaign reinforced the news that ulcers are a curable infection and that health can be greatly improved and money saved ... Overall, H. pylori infections show a worldwide decrease, more so in developed countries. Transmission occurs via food, ...
"Infection and Immunity. 18 (1): 85-93. PMC 421197. PMID 198377.. *^ Sebbane, F; Jarret, C.O.; Gardner, D; Long, D; Hinnebusch, ... Infection in a human occurs when a person is bitten by a flea that has been infected by biting a rodent that itself has been ... If the lymph node is overwhelmed, the infection can pass into the bloodstream, causing secondary septicemic plague and if the ... The pneumonic form of plague arises from infection of the lungs. It causes coughing and sneezing and thereby produces airborne ...
... , also known simply as paratyphoid, is a bacterial infection caused by one of the three types of Salmonella ... Paratyphoid C is a rare infection, generally seen in the Far East. It presents as a septicaemia with metastatic abscesses. ... Infection is characterized by a sustained fever, headache, abdominal pain, malaise, anorexia, a nonproductive cough (in early ... After ingestion, if the immune system is unable to stop the infection, the bacteria multiply and then spread to the bloodstream ...
Lipopolysaccharides of Actinobacillus pleuropneumoniae bind pig hemoglobin.. M Bélanger, C Bégin, M Jacques ... Lipopolysaccharides of Actinobacillus pleuropneumoniae bind pig hemoglobin. Message Subject (Your Name) has forwarded a page to ... you from Infection and Immunity Message Body (Your Name) thought you would be interested in this article in Infection and ... Thank you for sharing this Infection and Immunity article.. NOTE: We request your email address only to inform the recipient ...
In an attempt to gain insight into the events that take place during Actinobacillus pleuropneumoniae infection, the present ... Effects of Actinobacillus pleuropneumoniae hemolysin on porcine neutrophil function.. F A Udeze, S Kadis ... Effects of Actinobacillus pleuropneumoniae hemolysin on porcine neutrophil function. Message Subject (Your Name) has forwarded ... Thank you for sharing this Infection and Immunity article.. NOTE: We request your email address only to inform the recipient ...
... Freddy ... "Actinobacillus Pleuropneumoniae Infections in Pigs: The Role of Virulence Factors in Pathogenesis and Protection." Veterinary ... "Actinobacillus Pleuropneumoniae Infections in Pigs: The Role of Virulence Factors in Pathogenesis and Protection." VETERINARY ... Haesebrouck F, Chiers K, Van Overbeke I, Ducatelle R. Actinobacillus pleuropneumoniae infections in pigs: the role of virulence ...
Actinobacillus pleruropneumoniae transcriptome analysis during early infection - coping with a hostile environment. / Schou, ... Actinobacillus pleruropneumoniae transcriptome analysis during early infection - coping with a hostile environment. ... title = "Actinobacillus pleruropneumoniae transcriptome analysis during early infection - coping with a hostile environment", ... T1 - Actinobacillus pleruropneumoniae transcriptome analysis during early infection - coping with a hostile environment ...
Biomarkers of infection were screened for their possible role as evaluators of antibiotic treatment in an aerosol infection ... A similar Picture was seen for the biomarkers of infection. During the infection period, plasma C-reactive protein (CRP), ... an experimental model of porcine Actinobacillus pleuropneumoniae infection. Publication: Research - peer-review › Journal ... Classical swine fever virus infection modulates serum levels of INF-α, IL-8 and TNF-α in 6-month-old pigs. Publication: ...
"Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine, ... Actinobacillus pleuropneumoniae infections in pigs: the role of virulence factors in pathogenesis and protection ... Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine. Reiner, ... Development of a DIVA subjunit vaccine against Actinobacillus pleuropneumoniae infection. Maas, A; Meens, J; Baltes, N; Hennig- ...
... K-REx ... Experimental actinobacillus seminis infection of rams : a scanning electron microscopy study of seminal vesicles. Stockinger, ...
... Van Tonder, E.M.; ... Actinobacillus seminis infection in sheep in the Republic of South Africa. I. Identification of the problem. Login ... 1 vaccine was meticulously applied and the complete absence of Brucella ovis infection was established, of a total of 327 rams ... 25 out of 33 rams with subclinical infection and none out of 13 rams which showed no neutrophils in their semen. On 4 stud ...
... infection dose: 10.9 × 103 cfu/animal) were examined by culture during the first week after infection. In addition, tissue ... pleuropneumoniae serovar 7 strain AP 76 seems to occur more frequently during acute infection following effective lung ... Actinobacillus (A.) pleuropneumoniae is normally considered strictly adapted to the respiratory tract of swine. Despite this, ... Haesebrouck F, Chiers K, Van Overbeke I, Ducatelle R (1997) Actinobacillus pleuropneumoniae infections in pigs: the role of ...
Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages in ... Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages in ... Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages in ... T1 - Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages ...
The main causative organism of this disease is Actinobacillus … ... Actinobacillus Infections / microbiology* * Actinobacillus ... Molecular pathogenicity of the oral opportunistic pathogen Actinobacillus actinomycetemcomitans Annu Rev Microbiol. 2003;57:29- ... The main causative organism of this disease is Actinobacillus actinomycetemcomitans. A member of the Pasteurellaceae, A. ...
Cause - a bacterial infection (Actinobacillus lignieresi). This organism is normally present in the mouth of cattle. Under ... Cause - a fungal infection (Actinomyces bovis). This fungus is normally present in the mouth of healthy animals but it may ... Infection is usually acquired in calfhood but generally no clinical signs are seen until animals are at least four years old. ... Heavy infections cause a profuse watery scour which can lead to dehydration In yearlings and adult cattle a heavy infestation ...
Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine ... 2014). Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine. ... Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine ... Actinobacillus pleuropneumoniae is among the most important pathogens worldwide in pig production. The agent can cause severe ...
Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in nonoral infections. Periodontology 2000 20:122-135. ... Natural Transformation and DNA Uptake Signal Sequences in Actinobacillus actinomycetemcomitans. Ying Wang, Steve D. Goodman, ... Natural Transformation and DNA Uptake Signal Sequences in Actinobacillus actinomycetemcomitans. Ying Wang, Steve D. Goodman, ... Natural Transformation and DNA Uptake Signal Sequences in Actinobacillus actinomycetemcomitans. Ying Wang, Steve D. Goodman, ...
1999) Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in nonoral infections. Periodontology 2000 20:122-135. ... 1999) Virulence factors of Actinobacillus actinomycetemcomitans. Periodontology 2000 20:136-167.. OpenUrlCrossRefPubMedWeb of ... Actinobacillus actinomycetemcomitans is a gram-negative bacterium associated with several human diseases (8, 36, 47). The most ... 1991) Evidence for invasion of a human oral cell line by Actinobacillus actinomycetemcomitans. Infect. Immun. 59:2719-2726. ...
Actinobacillus Actinobacillus Infections Animals Bacterial Proteins Chromatography, High Pressure Liquid Electrophoresis, ... Actinobacillus suis-like organisms (ASLOs) have been isolated from the genital, respiratory, and digestive tracts of healthy ... One isolate was identified as Actinobacillus suis sensu stricto, based on the presence of apxIA and apxIIA but not aqxA, ... Two foals with congenital hypothyroidism-dysmaturity syndrome from separate farms developed ASLO infection. At necropsy, both ...
Thus, we propose that infection by Cdt-producing microbial species would impair host defense mechanisms and that this ... Actinobacillus actinomycetemcomitans: a new cause for granuloma of the parotid gland and buccal space. Plast. Reconstr. Surg. ... Actinobacillus actinomycetemcomitans immunosuppressive protein is a member of the family of cytolethal distending toxins ... We have previously shown that Actinobacillus actinomycetemcomitans produces an immunosuppressive factor that is encoded by the ...
... infection dose: 10.9 × 103 cfu/animal) were examined by culture during the first week after infection. In addition, tissue ... pleuropneumoniae serovar 7 strain AP 76 seems to occur more frequently during acute infection following effective lung ... Actinobacillus (A.) pleuropneumoniae is normally considered strictly adapted to the respiratory tract of swine. Despite this, ... From: Multi-organ spreading of Actinobacillus pleuropneumoniae serovar 7 in weaned pigs during the first week after ...
These findings confirm that IVI antigens used as vaccine candidates provide partial protection against APP infection in a mouse ... 2009). Positive role for rApxIVN in the immune protection of pigs against infection by Actinobacillus pleuropneumoniae. Vaccine ... 2015). Identification of Actinobacillus pleuropneumoniae genes preferentially expressed during infection using in vivo-induced ... Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model ...
... industrial applications and more information for Actinobacillus hominis. ... Actinobacillus hominis can rarely cause human infection.. Disclaimer: This information is presented as is. While every effort ... Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Actinobacillus. Industrial uses or economic ...
Heterogeneity of Actinobacillus actinomycetemcomitans strains in various human infections and relationships between serotype, ... Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus in systemic and nonoral infections in Finland. ... Age, dental infections, and coronary heart disease.. Mattila KJ, Asikainen S, Wolf J, Jousimies-Somer H, Valtonen V, Nieminen M ... Characterisation of Eubacterium-like strains isolated from oral infections.. Downes J, Munson MA, Spratt DA, Kononen E, Tarkka ...
Septicemic Actinobacillus suis infection in a neonatal piglet with multifocal necrotic glossitis. ...
Actinobacillus pleuropneumoniae is a widely studied bacterium, however its pathogenesis is not yet fully understood. The ... Actinobacillus pleuropneumoniae is described as a strict extracellular pathogen with tropism for lower respiratory tract. ... Actinobacillus pleuropneumoniae is described as a strict extracellular pathogen with tropism for lower respiratory tract. ... Actinobacillus pleuropneumonia is a swine (host) specific respiratory pathogen and the etiological agent of swine ...
Categories: Actinobacillus Infections Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Comparison of virulence of different Actinobacillus pleuropneumoniae serotypes and biotypes using an aerosol infection model. ... Evaluation of an enzyme-linked immunosorbent assay for serological surveillance of infection with Actinobacillus ... Actinobacillus pleuropneumoniae, p. 563-576. In B. E. Straw, J. J. Zimmerman, S. DAllaire, and D. J. Taylor (ed.), Diseases of ... An Actinobacillus pleuropneumoniae PCR typing system based on the apx and omlA genes-evaluation of isolates from lungs and ...
Actinobacillus pleuropneumoniae (APP) causes serious lung infections in pigs. Severe damage to the lungs, in many cases deadly ... In this study, the RNA extracted from visually unaffected and necrotic tissue from pigs infected with Actinobacillus ... miR-451 and miR-15a appear as very promising candidates for microRNAs involved in response to pathogen infection. This is the ... Actinobacillus pleuropneumoniae (APP) causes serious lung infections in pigs. Severe damage to the lungs, in many cases deadly ...
Actinobacillus lignieresii Actinobacillus suis Pasteurella multocida Pasteurella caballi Staphylococcus hyicus s... more ... Common bacteria involved in herbivore bite wound infections include the following: ... Cummings P. Antibiotics to prevent infection in patients with dog bite wounds: a meta-analysis of randomized trials. Ann Emerg ... Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis. 2005 Nov 15. 41(10): ...
"Development of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae infection". Vaccine. 24 (49-50): 7226-37. doi: ... Lack of response commonly results from clinical factors such as diabetes, steroid use, HIV infection, or age.[citation needed] ... 19 July 2017 Vaccines promoted as key to stamping out drug-resistant microbes "Immunization can stop resistant infections ... Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or ...
"Development of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae infection". Vaccine. 24 (49-50): 7226-37. doi: ... "19 July 2017 Vaccines promoted as key to stamping out drug-resistant microbes "Immunization can stop resistant infections ... Robinson HL, Pertmer TM (2000). DNA vaccines for viral infections: basic studies and applications. Advances in Virus Research. ... Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or ...
Infections caused by Actinobacillus spp: identification of new Actinobacillus spp. virulence factors ... Infections caused by Escherichia coli : Postweaning diarrhea and septicemia due to Escherichia coli. Study of virulence ... Infections caused by Streptococcus suis: Studies on virulence factors of S. suis serotype 2 ...
  • Actinobacillus pleuropneumoniae infections in pigs: the role of virulence factors in pathogenesis and protection. (ugent.be)
  • Haesebrouck F, Chiers K, Van Overbeke I, Ducatelle R. Actinobacillus pleuropneumoniae infections in pigs: the role of virulence factors in pathogenesis and protection. (ugent.be)
  • The global transcriptional patterns of Ap serotype 2 and 6 isolated from lung tissue biopsies of 25 experimentally infected pigs were compared at four time points between 6 and 48 hours post infection. (dtu.dk)
  • Following infection of 12 pigs, clinical signs of pneumonia developed within 20 h, whereafter the animals received a single dose of either danofloxacin (2.5 mg/kg) or tiamulin (10 mg/kg). (dtu.dk)
  • This indicates that CRP, zinc, ascorbic acid and to a lesser extent interleukin-6 and alpha-tocopherol might be used to evaluate antibiotic treatment of acute Ap-infection ill pigs. (dtu.dk)
  • Actinobacillus pleuropneumonia is a swine (host) specific respiratory pathogen and the etiological agent of swine pleuropneumonia which affects pigs of all ages, many being asymptomatic carriers. (frontiersin.org)
  • even pigs that survive the acute phase can reach subclinical infection and be persistent carriers, harboring App in the tonsils and suffering from chronic lung lesions ( 12 - 15 ). (frontiersin.org)
  • Actinobacillus pleuropneumoniae (APP) causes serious lung infections in pigs. (biomedcentral.com)
  • In this study, the RNA extracted from visually unaffected and necrotic tissue from pigs infected with Actinobacillus pleuropneumoniae was subjected to small RNA deep sequencing. (biomedcentral.com)
  • Actinobacillus pleuropneumoniae is a Gram-negative bacterium that causes porcine pleuropneumonia, a highly infectious fatal respiratory disease of pigs ( 1 ). (asm.org)
  • In contrast, natural or experimental infection with A. pleuropneumoniae generally elicits protection against homologous and heterologous serotype infections in pigs ( 7 ). (asm.org)
  • Duration of efficacy of ceftiofur crystalline free acid sterile suspension against clinical disease in grower pigs challenged with Actinobacillus pleuropneumoniae. (aasv.org)
  • To evaluate the duration of efficacy of a single dose of ceftiofur crystalline free acid sterile suspension (CCFA-SS) against clinical disease in grower pigs inoculated intratracheally with Actinobacillus pleuropneumoniae . (aasv.org)
  • The mechanism often is that pigs experience trauma and/or bacterial infection -- lameness -- cannot compete -- compromised growth and vigor -- additional trauma and bacterial infections -- culled or require euthanasia. (nationalhogfarmer.com)
  • The objective of the present work was to elucidate the potential relationship between Mycoplasma hyopneumoniae infection and seroconversion dynamics and climatological conditions in four groups of pigs from the same farm born in different seasons of the year. (springer.com)
  • Sibila M, Nofrarias M, Lopez-Soria S, Segales J, Riera P, Llopart D, Calsamiglia M (2007a) Exploratory field study on Mycoplasma hyopneumoniae infection in suckling pigs. (springer.com)
  • Sibila M, Nofrarias M, Lopez-Soria S, Segales J, Valero O, Espinal A, Calsamiglia M (2007b) Chronological study of Mycoplasma hyopneumoniae infection, seroconversion and associated lung lesions in vaccinated and non-vaccinated pigs. (springer.com)
  • A cDNA microarray of pig with 6,420 probes from immune tissues and cells was used to compare gene expression in peripheral blood leukocytes of two pigs showing extreme performance in their response to infection with Actinobacillus pleuropneumoniae. (edu.au)
  • Principal components analyses were used to identify the two most extreme-performing pigs after infection (i.e., pigs whose measured responses to infection fell at the extremes). (edu.au)
  • 2009 ). However, so far to our knowledge, there is no high-throughput proteomics analysis of serum after APP infection in pigs has been performed for understanding host immune defense. (springeropen.com)
  • Infection (Actinobacillus pleuropneumoniae)-mediated suppression of oxidative hepatic drug metabolism and cytochrome P4503A mRNA levels in pigs. (semanticscholar.org)
  • This information helped determine that this species is closely related to Actinobacillus suis and Actinobacillus hominus. (wikipedia.org)
  • Haemophilus parasuis, Streptococcus suis, Actinobacillus suis, Erysipelothrix rhusiopathiae) and can cause acute joint infections. (nationalhogfarmer.com)
  • Treatment of infections caused by bacteria sensitive to amoxicillin, Pleuropneumonia caused by Actinobacillus pleuropneumoniae , Meningitis caused by Streptococcus suis . (dechra.co.uk)
  • Haemophilus parasuis and Streptococcus suis tend to hit the younger pig but can be brought on with a concurrent PRRSV infection. (pigprogress.net)
  • Here we report on the production of transgenic mice that ectopically expressed PG-1 and compare their susceptibilities to Actinobacillus suis infection with those of their wild-type (WT) littermates. (scialert.net)
  • Actinobacillus pleuropneumoniae (App) is a respiratory pathogen member of the family Pasteurellaceae and etiological agent of swine pleuropneumonia ( 1 , 2 ). (frontiersin.org)
  • Actinobacillus pleuropneumoniae is a gram-negative, encapsulated respiratory pathogen of swine and the causative agent of porcine pleuropneumonia ( 14 ). (asm.org)
  • Actinobacillus pleuropneumoniae is the etiologic agent of porcine pleuropneumonia, which causes serious economic losses in the pig farming industry worldwide. (asm.org)
  • Diseases such as actinobacillus pleuropneumonia, migrating ascarid worms, miscellaneous generalised infections may also result in peritonitis. (thepigsite.com)
  • Actinobacillus (A.) pleuropneumoniae is the causative agent of porcine pleuropneumonia. (biomedcentral.com)
  • The IDEXX APP-ApxIV Ab Test is an enzyme immunoassay for the detection of antibodies against Actinobacillus pleuropneumoniae (APP), the causative pathogen for swine pleuropneumonia, in serum and plasma of swine independently of the APP serotype. (idexx.com)
  • Swine pleuropneumonia caused by Actinobacillus pleuropneumoniae (APP) is a highly contagious pulmonary disease that may cause important economic losses. (idexx.com)
  • Porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae (APP) is a swine respiratory disease with an important impact around the world either as a single infection or part of the porcine respiratory disease complex. (springeropen.com)
  • Actinobacillus pleuropneumoniae (APP) causes porcine pleuropneumonia characterized by acute hemorrhagic fibrous porcine pleuropneumonia with respiratory distress (Sassu et al. (springeropen.com)
  • Treatment of Pleuropneumonia caused by Actinobacillus pleuropneumoniae susceptible to tiamulin. (dechra.co.uk)
  • In conclusion, multi-organ spreading of A. pleuropneumoniae serovar 7 strain AP 76 seems to occur more frequently during acute infection following effective lung colonization than previously thought. (biomedcentral.com)
  • and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline. (drugs.com)
  • It is caused by Tropheryma whipplei and encompasses asymptomatic carriage of the organism to a wide spectrum of clinical pathologic conditions, including acute and chronic infections ( 1 , 2 ). (cdc.gov)
  • Actinobacillus ( A. ) pleuropneumoniae , a Gram-negative bacterium belonging to the family Pasteurellaceae , is one of the most important respiratory tract pathogens in the pig industry. (biomedcentral.com)
  • This bacterium has also been isolated from a variety of other infections, notably endocarditis. (asm.org)
  • Actinobacillus actinomycetemcomitans is a gram-negative bacterium associated with several human diseases ( 8 , 36 , 47 ). (asm.org)
  • Actinobacillus pleuropneumoniae is a widely studied bacterium, however its pathogenesis is not yet fully understood. (frontiersin.org)
  • A. pleuropneumoniae is genetically closely affiliated with Actinobacillus lignieresii ( 6 , 25 ), a bacterium commonly found in the mucosal membranes of cattle and the cause of chronic infections in the tongue and jaw (tree tongue). (asm.org)
  • Actinobacillus actinomycetemcomitans, an oral bacterium implicated in the etiology of periodontal diseases, produces a leukotoxin that selectively lyses primate neutrophils and monocytes, the major populations of defense cells in the periodontium. (diva-portal.org)
  • Aggregatibacter (Actinobacillus) actinomycetemcomitans is a bacterium mainly associated with aggressive forms of periodontitis. (diva-portal.org)
  • Using purified recombinant CDT proteins from the periodontopathic bacterium Actinobacillus actinomycetemcomitans , the authors investigated which combination of toxin proteins produce cell cycle inhibition and which bound and/or entered into host cells. (microbiologyresearch.org)
  • We have previously shown that Actinobacillus actinomycetemcomitans produces an immunosuppressive factor that is encoded by the cdtB gene, which is homologous to a family of cytolethal distending toxins (Cdt) expressed by several Gram-negative bacteria. (jimmunol.org)
  • Which common bacteria cause wound infections from herbivore bites? (medscape.com)
  • Actinobacillus equuli is a gram-negative, non-motile rod bacteria from the family Pasteurellaceae. (wikipedia.org)
  • It was previously thought that this bacteria was limited to the species level, however it is now divided into two subspecies of Actinobacillus equuli which include: A. equuli subsp. (wikipedia.org)
  • A conspicuous feature of the swine respiratory disease (SRD) complex is the regularity with which the causative bacteria and viral agents appear in the US swine population, including herds with subclinical infections. (thepigsite.com)
  • Intramammary infections caused by coliform bacteria typically result from entry of the bacteria via the teat canal and multiplying in the gland. (biomin.net)
  • Treatment of infections in chickens, turkeys and ducks caused by bacteria susceptible to amoxicillin. (dechra.co.uk)
  • PRDC is comprised of a number of infections involving viruses, especially PRRSV, swine influenza virus etc, Mycoplasma hyopneumoniae , the cause of enzootic pneumonia (EP) and bacteria. (pigprogress.net)
  • Results: The rate of infection was 45% in patients suffering from periodontal disease and the isolated bacteria had the ability to adhere to human epithelial cells of the mouth, also had the ability to produce bacteriocins as the substantive factors for the bacterial growth among the closer species of bacteria, and the presence of capsule, which was the most important virulence factor. (iasj.net)
  • We report 3 cases of koala bite wound infection with Lonepinella koalarum -like bacteria requiring antimicrobial and surgical management. (cdc.gov)
  • Clinicians should isolate bacteria and determine antimicrobial susceptibilities when managing these infections. (cdc.gov)
  • In order to elucidate the species boundaries, six strains of the phylogenetically closely related species Actinobacillus lignieresii were also included. (asm.org)
  • Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages in humans. (elsevier.com)
  • Wu Y, Yan J, Chen LL, Gu Z. Association between infection of different strains of Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in subgingival plaque and clinical parameters in chronic periodontitis. (thejcdp.com)
  • Susceptibilities of different Actinobacillus actinomycetemcomitans strains to lactoperoxidase-iodide-hydrogen peroxide combination and different antibiotics. (nih.gov)
  • Although not all Aa strains can determine an AgP, high levels of ltxA have been always detected in AgP related to Aa infection [ 5 ]. (hindawi.com)
  • Periodontal infections with strains producing high levels of the leukotoxin are strongly associated with severe disease. (diva-portal.org)
  • Mixing animals infected with virulent APP strains together with immunologically naive animals, inappropriate management, concurrent infections (e.g. (idexx.com)
  • To better understand the role of natural host defence mechanisms in A. actinomycetemcomitans infections, the interaction of phenotypically diverse strains of this pathogen with human neutrophils was assessed directly using techniques such as genetic labelling with the gene for green fluorescent protein, fluorescence-activated cell sorting and fluorescence imaging. (elsevier.com)
  • Actinobacillus equuli subspecies equuli is not hemolytic and is found in equine and porcine hosts. (wikipedia.org)
  • Another subspecies exists and is classified as Actinobacillus equuli subsp. (wikipedia.org)
  • Less commonly, A. equuli will cause disease in adult horses, resulting in respiratory infections. (wikipedia.org)
  • Actinobacillus equuli genome's size is approximately 1.7 GDa and contains 40% guanine and cytosine in its genetic makeup. (wikipedia.org)
  • Important risk factors for foals acquiring an infection with A. equuli include failure of passive transfer, unsanitary foaling environments, and the presence of immunosuppressive conditions. (wikipedia.org)
  • Actinobacillus equuli is an important cause of meningoencephalitis in foals. (merckvetmanual.com)
  • Amplified fragment length polymorphism (AFLP) was evaluated as a method for genotypic characterization and subtyping within the bacterial species Actinobacillus pleuropneumoniae . (asm.org)
  • De-regulation of many microRNA species has been associated with pathological states including cancer, neurodegenerative disorders, diabetes, bacterial infections and immunological response to the latter [ 5 ]. (biomedcentral.com)
  • Species-specific multiplex PCR for the diagnosis of Brucella ovis, Actinobacillus seminis, and Histophilus somni infection in rams. (bireme.br)
  • The aim of this study was to develop a multiplex PCR assay for simultaneous detection of Brucella ovis, Actinobacillus seminis, and Histophilus somni with species-specific primers applied to biological samples for molecular diagnosis of these infections. (bireme.br)
  • The pig is particularly susceptible to infection, although, other farm species such as turkeys and sheep are also vulnerable, as are marine animals including seals and other cetacea. (thepigsite.com)
  • Actinomyces radicidentis , a recently described species, has been isolated with polymerase chain reaction from patients with endodontic infections. (medscape.com)
  • Other bacterial species that often are copathogens to Actinomyces species may aid spread of infection by inhibiting host defenses and reducing local oxygen tension. (medscape.com)
  • Marco-Ramell, Miller, Nöbauer, Möginger, Segalés, Razzazi-Fazeli, Kolarich, Bassols: Proteomics on porcine haptoglobin and IgG/IgA show protein species distribution and glycosylation pattern to remain similar in PCV2-SD infection. (antikoerper-online.de)
  • 0.001), and the most common bacterial isolates were Streptococcus zooepidemicus, Streptococcus pneumoniae and Pasteurella/Actinobacillus-like species. (surrey.ac.uk)
  • With both P. gingivalis and A. actinomycetemcomitans, positive correlations between elevated IgG level and infections by these microorganisms were found in the puberty gingivitis and adult periodontitis groups. (elsevier.com)
  • Actinobacillus actinomycetemcomitans is a member of the family Pasteurellaceae and a major causative agent of periodontitis. (asm.org)
  • Actinobacillus actinomycetemcomitans , a gram-negative, facultative, nonmotile coccobacillus, is a major causative agent of localized juvenile periodontitis and other forms of chronic periodontitis ( 36 ). (asm.org)
  • The gram-negative coccobacillus, Actinobacillus actinomycetemcomitans , is the putative agent for localized juvenile periodontitis, a particularly destructive form of periodontal disease in adolescents. (asm.org)
  • Tissue localization of Actinobacillus actinomycetemcomitans in human periodontitis. (elsevier.com)
  • Recent immunohistological studies have suggested that Actinobacillus actinomycetemcomitans is present in the gingival tissues in juvenile periodontitis lesions. (elsevier.com)
  • Fingerprint Dive into the research topics of 'Tissue localization of Actinobacillus actinomycetemcomitans in human periodontitis. (elsevier.com)
  • Aggressive periodontitis is associated with Actinobacillus actinomycetemcomitans, a Gram-negative capnophilic microorganism. (elsevier.com)
  • Secondary bacterial infections caused by Pasteurella multocida, Actinobacillus pleuropneumoniae, Streptococcus spp. (dechra.co.uk)
  • For the treatment of the clinical signs associated with porcine respiratory disease caused by Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae susceptible to doxycycline. (dechra.co.uk)
  • Where clinical disease is present in the flock, to reduce mortality, morbidity, and clinical signs and to reduce lesions due to Pasteurellosis caused by Pasteurella multocida or to reduce morbidity and lesions in respiratory infections caused by Ornithobacterium rhinotracheale (ORT) . (dechra.co.uk)
  • Treatment and metaphylaxis of Enzootic Pneumonia caused by Mycoplasma hyopneumoniae , including infections complicated by Pasteurella multocida susceptible to tiamulin. (dechra.co.uk)
  • Pasteurella multocida usually follows a mycoplasma infection and Actinobacillus pleuropneumoniae usually hits the late grower or early finisher pig when maternally derived antibodies subside at about ten weeks. (pigprogress.net)
  • Aim: To obtain an increased understanding of how the porcine lung pathogen Actinobacillus pleuropneumoniae (Ap) establish infection in the host. (dtu.dk)
  • Understanding the means by which a pathogen establishes and maintains infection in the host organism is the first step towards controlling disease. (dtu.dk)
  • Actinobacillus pleuropneumoniae is described as a strict extracellular pathogen with tropism for lower respiratory tract. (frontiersin.org)
  • Moreover, miR-664-5p, miR-451 and miR-15a appear as very promising candidates for microRNAs involved in response to pathogen infection. (biomedcentral.com)
  • Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic (to fight a disease that has already occurred, such as cancer). (wikipedia.org)
  • Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen ), or therapeutic (e.g., vaccines against cancer , which are being investigated). (wikipedia.org)
  • Erysipelothrix rhusiopathiae is viewed as an occupational pathogen causing 'Erysipeloid', a rare disease that is usually only seen in individuals exposed to high levels of infection such as workers on farms and in slaughterhouses, veterinarians, butchers and fishermen. (thepigsite.com)
  • Influence of Actinobacillus pleuropneumoniae serotype 2 and its cytolysins on porcine neutrophil chemiluminescence. (ugent.be)
  • Actinobacillus seminis infection in sheep in the Republic of South Africa. (up.ac.za)
  • Several studies have shown a greater prevalence of HLA-B27 antigen in WD patients (26% versus 8% in European and American populations, respectively) ( 16 , 22 ), but no causal association between HLA-B27 presence and infection susceptibility has been demonstrated. (asm.org)
  • Our objective was to detect genes that may be involved in conferring heritable differences in susceptibility to common infections in intensive pig production. (edu.au)
  • Infections caused by Escherichia coli : Postweaning diarrhea and septicemia due to Escherichia coli. (thepigsite.com)
  • Bacterial meningoencephalitis often affects very young farm animals because of blood poisoning caused by Escherichia coli or a streptococcal infection. (merckvetmanual.com)
  • Gastric acidity is a major barrier to colonization and infection of the gastrointestinal tract by microorganisms and is a first line of defense against microbial pathogens that infect their host via the oral route. (asm.org)
  • Mycoplasma and bacterial infections account for most of the arthritis diagnosed at ISUVDL. (nationalhogfarmer.com)
  • Mycoplasma infections are often primary causes of arthritis, meaning they do not need obvious predisposing factors to cause disease. (nationalhogfarmer.com)
  • For the treatment of clinical respiratory infections associated with Mycoplasma gallisepticum susceptible to doxycycline. (dechra.co.uk)
  • Biomarkers of infection were screened for their possible role as evaluators of antibiotic treatment in an aerosol infection model of porcine pneumonia caused by Actinobacillus pleuropneumoniae (Ap). (dtu.dk)
  • For this, organ samples (blood, liver, spleen, kidney, tarsal and carpal joints, meninges, pleural and pericardial fluids) from weaners ( n = 47) infected experimentally with A. pleuropneumoniae serovar 7 by aerosol infection (infection dose: 10.9 × 10 3 cfu/animal) were examined by culture during the first week after infection. (biomedcentral.com)
  • Although their virulence and regional prevalence vary, all the serotypes cause disease, and with the growing emergence of antibiotic resistance and the rising concern about food safety, vaccination to prevent A. pleuropneumoniae infections is of increasing relevance ( 2 , 4 ). (asm.org)
  • However, this organism does not cause the human skin condition of 'Erysipelas', this which is the result of a Streptococcus bacterial infection. (thepigsite.com)
  • A clinical palpation and semen smear examination of 647 rams submitted to the Regional Veterinary Laboratory during 1967 revealed that 42 (6,5%) of these animals had clinical epididymitis or orchitis, 6 (0,9%) showed other types of genital lesions and 98 (15,1%) suffered from subclinical genital infection. (up.ac.za)
  • A. seminis was isolated from 5 out of 6 of these rams with clinical lesions and 10 out of 15 of those which showed evidence of subclinical infection. (up.ac.za)
  • To evaluate lung lesions at slaughter after three-dose vaccination with a subunit Actinobacillus pleuropneumoniae vaccine containing ApxI, ApxII, ApxIII, and an outer membrane protein. (aasv.org)
  • Actinobacillus pleuropneumoniae -related lesions and ADG did not differ between control and treatment groups. (aasv.org)
  • Often the lesions of arthritis are chronic in the cases presented to the diagnostic laboratory, therefore a specific cause remains "undetermined" but most of these are a sequel to a previous bacterial infection (Figure 3). (nationalhogfarmer.com)
  • CVPC quantification by means of lung lesion scoring is frequently used to estimate the incidence and severity of lung lesions associated to M . hyopneumoniae infections, at experimental, herd and abattoir levels [ 4 - 6 ]. (pubmedcentralcanada.ca)
  • Immunopathological events are considered to play an important role in both M . hyopneumoniae infection pattern and development of the associated lung lesions [ 3 ]. (pubmedcentralcanada.ca)
  • Actinobacillus seminis is frequently isolated from the lesions that produces clinical signs and reproductive discrepancies in ram wherein transmission implicit through direct contact between mucous membrane from all orifices during pre-mating period owing to boost up homosexual activity in which ewe considered as the intermediate carriers upholding ewe to lamb transmission. (biology-online.org)
  • Thank you for sharing this Infection and Immunity article. (asm.org)
  • Message Body (Your Name) thought you would be interested in this article in Infection and Immunity. (asm.org)
  • However, even a partial, late, or weak immunity, such as a one resulting from cross-immunity to a strain other than the target strain, may mitigate an infection, resulting in a lower mortality rate, lower morbidity, and faster recovery. (wikipedia.org)
  • As a conclusion, APP could delay host inflammatory response to the infection at early stage, and induced innate immunity to convert from adhesion, interaction into complement activation, proteasome digestion, bacterial invasion at later stage. (springeropen.com)
  • Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus in systemic and nonoral infections in Finland. (nih.gov)
  • The main causative organism of this disease is Actinobacillus actinomycetemcomitans. (nih.gov)
  • A notable characteristic of SRD is the frequency with which the causative bacterial agents appear in the swine population, including herds with subclinical infection. (thepigsite.com)
  • The most common causative agents of these infections are Brucella ovis, Actinobacillus seminis, and Histophilus somni. (bireme.br)
  • Mesenteric lymphangitis and sepsis due to RTX toxin-producing Actinobacillus spp in 2 foals with hypothyroidism-dysmaturity syndrome. (nextbio.com)
  • Recombinant Actinobacillus actinomycetemcomitans cytolethal distending toxin proteins are required to interact to inhibit human cell cycle progression and to stimulate human leukocyte cytokine synthesis. (microbiologyresearch.org)
  • The present model provides a valuable tool in the evaluation of antibiotic treatments, offering the advantage of clinical and pathological examinations combined with the use of biochemical infection markers. (dtu.dk)
  • A. seminis and A. seminis-like organisms were isolated from semen specimens of 18 out of 35 rams with clinical epididymitis or orchitis, 25 out of 33 rams with subclinical infection and none out of 13 rams which showed no neutrophils in their semen. (up.ac.za)
  • Infection is usually acquired in calfhood but generally no clinical signs are seen until animals are at least four years old. (dairyaustralia.com.au)
  • Lack of response commonly results from clinical factors such as diabetes , steroid use, HIV infection , or age. (wikipedia.org)
  • Clinical efficacy of Enrofloxacin and other quinolones against artificially induced E. coli infection in young chicks. (ugent.be)
  • The bacteriology section publishes research findings which focus on clinical, macro pathological, cell and molecular biological aspects of bacterial infections. (biomedcentral.com)
  • This study examined the serum IgG and IgM responses against Porphyromonas gingivalis and 3 serotypes of Actinobacillus actinomycetemcomitans, and the correlations of these responses with age and homologous infection. (elsevier.com)
  • For example, it has been estimated that most herds are infected with one or more serotypes of Actinobacillus pleuropneumoniae , although not all serotypes have the same economic importance. (thepigsite.com)
  • A. actinomycetemcomitans can also spread from the oral cavity, causing a variety of nonoral infections ( 31 , 36 ). (asm.org)
  • Cat bite wounds: risk factors for infection. (medscape.com)
  • these infections may result from bite wounds or other traumatic injuries near the head or spine. (merckvetmanual.com)
  • When secondary or concomitant infections by other respiratory bacterial organisms are also implicated, enzootic pneumonia (EP) occurs [ 3 ]. (pubmedcentralcanada.ca)
  • We report 3 cases of human wound infection involving Lonepinella -like organisms occurring after koala bites in Queensland, Australia. (cdc.gov)
  • Efficacy of a subunit vaccine against Actinobacillus pleuropneumoniae in an endemically infected swine herd. (aasv.org)
  • While collected semen may be contaminated, the routine use of antibiotics in diluents should eliminate infection. (thepigsite.com)
  • Cases resulting from rickettsial and bacterial infections can be treated with appropriate antibiotics, while fungal infections can be treated with specific antifungal drugs. (merckvetmanual.com)
  • Effects of Actinobacillus pleuropneumoniae hemolysin on porcine neutrophil function. (asm.org)
  • In an attempt to gain insight into the events that take place during Actinobacillus pleuropneumoniae infection, the present study was designed to ascertain the effects of bacterial toxicity on porcine neutrophil functions and viability. (asm.org)
  • On 4 stud farms where Elberg Rev. 1 vaccine was meticulously applied and the complete absence of Brucella ovis infection was established, of a total of 327 rams examined, 10 (3,6%) were found to be clinically and 72 (22,0%) subclinically affected. (up.ac.za)
  • These findings confirm that IVI antigens used as vaccine candidates provide partial protection against Actinobacillus pleuropneumoniae infection in a mouse model, which could be used as potential vaccine candidates in piglets. (frontiersin.org)
  • Actinobacillus pleuropneumoniae can be transmitted between herds through various vectors, including direct contact with infected animals, contaminated aerosols and fomites ( 10 , 11 ). (frontiersin.org)
  • These animals represent the major source of dissemination of the infection between herds. (idexx.com)
  • Fifty randomly selected fattening pig herds were studied to investigate the epidemiological characteristics of infections with Actinobacillus pleuropneumoniae serovars 2, 3 and 9, and to identify risk factors for their within-herd seroprevalences. (bmj.com)
  • A previous study indicated that lipopolysaccharides (LPS) extracted from Actinobacillus pleuropneumoniae bind two low-molecular-mass proteins, of approximately 10 and 11 kDa, present in porcine respiratory tract secretions (M. Bélanger, D. Dubreuil, and M. Jacques, Infect. (asm.org)
  • This study used iTRAQ to identify differentially expressed proteins (DEPs) in pig serum in response to APP infection. (springeropen.com)
  • Mutations in VP0 and 2C Proteins of Duck Hepatitis A Virus Type 3 Attenuate Viral Infection and Virulence[J]. Vaccines,2019, 7:111, doi:10.3390/vaccines7030111. (sicau.edu.cn)
  • Eleven biopsies were obtained from gingiva adjacent to A. actinomycetemcomitans infected pockets, while the remaining three control biopsies were obtained from gingiva adjacent to pockets where subgingival A. actinomycetemcomitans infection could not be detected. (elsevier.com)
  • Riggio MP, Macfarlane TW, Mackenzie D, Lennon A, Smith AJ, Kinane D. Comparison of polymerase chain reaction and cultural methods for detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in subgingival plaque samples. (thejcdp.com)
  • To isolate and identify Actino-bacillus actinomycetemcomitans because of its importance in periodontal diseases, to show their incidence in periodontal infections, and to study their important virulence factors. (iasj.net)
  • Neutrophils are initially the predominant cells involved in the host defence of bacterial infections, including periodontal disease. (elsevier.com)
  • Maia A, Goldstein FW, Acar JF, Roland F. Isolation of Eikenella corrodens from human infections: report of six cases. (medscape.com)