Infections with bacteria of the genus ACTINOBACILLUS.
A genus of PASTEURELLACEAE described as gram-negative, nonsporeforming, nonmotile, facultative anaerobes. Most members are found both as pathogens and commensal organisms in the respiratory, alimentary, and genital tracts of animals.
A species of gram-negative, facultatively anaerobic coccobacillus-shaped bacteria that has been isolated from pneumonic lesions and blood. It produces pneumonia with accompanying fibrinous pleuritis in swine.
A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.
A species of gram-negative bacteria in the genus ACTINOBACILLUS. It is mainly a pathogen of PIGS, but also can infect HORSES.
Inflammation of the lung parenchyma that is associated with PLEURISY, inflammation of the PLEURA.
A genus of gram-negative bacteria in the genus ACTINOBACILLUS, which is pathogenic for HORSES and PIGS.
Diseases of domestic swine and of the wild boar of the genus Sus.
A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.
Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
A genus of PASTEURELLACEAE. Members are nonmotile, Gram-negative, facultatively anaerobic rods or coccobacilli. Its members are X factor (HEMIN) independent and variably dependent on V factor (NAD).
Toxins produced, especially by bacterial or fungal cells, and released into the culture medium or environment.
A family of coccoid to rod-shaped nonsporeforming, gram-negative, nonmotile, facultatively anaerobic bacteria that includes the genera ACTINOBACILLUS; HAEMOPHILUS; MANNHEIMIA; and PASTEURELLA.
The oldest recognized genus of the family PASTEURELLACEAE. It consists of several species. Its organisms occur most frequently as coccobacillus or rod-shaped and are gram-negative, nonmotile, facultative anaerobes. Species of this genus are found in both animals and humans.
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
A disease characterized by suppurative and granulomatous lesions in the respiratory tract, upper alimentary tract, skin, kidneys, joints, and other tissues. Actinobacillus lignieresii infects cattle and sheep while A. equuli infects horses and pigs.
Proteins from BACTERIA and FUNGI that are soluble enough to be secreted to target ERYTHROCYTES and insert into the membrane to form beta-barrel pores. Biosynthesis may be regulated by HEMOLYSIN FACTORS.
A species of gram-negative bacteria in the genus ACTINOBACILLUS, which causes EPIDIDYMITIS in SHEEP.
Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Oral tissue surrounding and attached to TEETH.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Proteins found in any species of bacterium.
A class of carrier proteins that bind to TRANSFERRIN. Many strains of pathogenic bacteria utilize transferrin-binding proteins to acquire their supply of iron from serum.
A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
The functional hereditary units of BACTERIA.

Pulmonary lesions in guinea pigs experimentally infected with Actinobacillus pleuropneumoniae (A.p.) serovar 1. (1/272)

Pathological studies were carried out on the lungs of guinea pigs intratracheally inoculated with 4.6 x 10(6-8) colony forming units (CFU)/head of Actinobacillus pleuropneumoniae serovar 1. All animals in the highest dose group died within 24 hr post inoculation (hpi) and showed pulmonary lesions being hemorrhagic in nature while all animals in the lowest dose group were killed as scheduled at 11 days post inoculation (dpi) and showed only hyperplasia of peribronchial lymphoid tissues. In the middle dose group, two died within 24 hpi, two died at 9 dpi, and the remaining one was killed at 11 dpi. Two guinea pigs which died at 9 dpi showed fibrinonecrotic pleuropneumonia which is the most characteristic acute pulmonary lesion in swine, and has not yet been reproduced in laboratory animals up to the present time. This suggests that guinea pigs may be a useful laboratory animal for studying the pathogenesis of Actinobacillus pleuropneumoniae infection in swine.  (+info)

Vaccination and protection of pigs against pleuropneumonia with a vaccine strain of Actinobacillus pleuropneumoniae produced by site-specific mutagenesis of the ApxII operon. (2/272)

The production of toxin (Apx)-neutralizing antibodies during infection plays a major role in the induction of protective immunity to Actinobacillus pleuropneumoniae reinfection. In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Expression of the structural toxin, ApxIIA, and of the two genes required for its secretion, apxIB and apxID, still occurs in this strain. The resulting mutant strain, HS93C- Ampr, was found to secrete the unactivated toxin. Pigs vaccinated with live HS93C- Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae. This is the first reported vaccine strain of A. pleuropneumoniae which can be delivered live to pigs and offers cross-serovar protection against porcine pleuropneumonia.  (+info)

Actinobacillus pleuropneumoniae osteomyelitis in pigs demonstrated by fluorescent in situ hybridization. (3/272)

Necrotizing osteomyelitis and fibrinopurulent arthritis with isolation of Actinobacillus pleuropneumoniae serotype 2 is reported in two pigs from a herd with lameness and mild coughing problems among 8 to 12-week-old pigs. Application of fluorescent in situ hybridization targeting 16S ribosomal RNA of A. pleuropneumoniae in formalin-fixed tissue was performed to verify the association of A. pleuropneumoniae with the bone and joint lesions. By in situ hybridization A. pleuropneumoniae was demonstrated as multiple microcolonies or single cells dispersed in focal fibrinonecrotizing pleuropneumonia, in joints with arthritis, and in bone necroses including lysis of growth plate and suppurative inflammation in the adjacent trabecular metaphysis, thus demonstrating that well-known infections manifest new, unusual lesions.  (+info)

Agents of the "suis-ide diseases" of swine: Actinobacillus suis, Haemophilus parasuis, and Streptococcus suis. (4/272)

In recent years, Actinobacillus suis, Haemophilus parasuis, and Streptococcus suis have emerged as important pathogens of swine, particularly in high health status herds. Their association with a wide range of serious clinical conditions and has given rise to the moniker "suis-ide diseases." These organisms are early colonizers and, for that reason, are difficult to control by management procedures such as segregated early weaning. Vaccination, serodiagnostic testing, and even serotyping are complicated by the presence of multiple serotypes, cross-reactive antigens, and the absence of clear markers for virulence. In this review, we discuss our current understanding of the pathogenesis, epidemiology, and management of the causative agents of the "suis-ide diseases" of swine.  (+info)

Phenotypic variation in Actinobacillus actinomycetemcomitans during laboratory growth: implications for virulence. (5/272)

This study examined alteration of specific virulence traits associated with phenotypic changes seen when a low-passage disease-associated and well maintained parent strain of Actinobacillus actinomycetemcomitans was compared to a laboratory-grown spontaneous variant/mutant. Clinical isolates of A. actinomycetemcomitans recovered from periodontitis patients typically grow as rough, adherent colonies on primary culture but undergo transformation to smooth, non-adherent colonies following repeated passage in vitro. The relationship of these phenotypic changes to the virulence of the organism or to the processes that underlie this transformation are not understood. A fresh clinical isolate, designated strain CU1000, was obtained from the first molar site of a patient with classical signs of localized juvenile periodontitis and used as the parent strain to study virulence-related phenotypes. Following several passages of CU1000 on selective agar, a spontaneous variant that demonstrated smooth, opaque, non-adherent colonies was isolated and designated strain CU1060. This study compared the properties of these two strains with respect to colony morphology, autoaggregation, surface appendages, adherence to saliva-coated hydroxyapatite (SHA), LPS chemotype and activity, induction of fibroblast proteinase activity and antigenic properties. CU1000 demonstrated rough, raised, star-positive colonies which upon electron microscopic examination revealed the presence of large, flexible, bundled fibrils. In addition, CU1000 showed adherence to SHA, several unique protein antigens and elevated endotoxin and fibroblast proteinase activity. CU1060, on the other hand, showed minimal adherence to SHA and fewer reactive proteins compared to the fresh clinical isolates. This strain formed smooth, opaque colonies on agar, showed minimal fibril formation and limited endotoxin and fibroblast-proteinase-inducing activity. These findings demonstrate that clinical isolates of A. actinomycetemcomitans undergo significant virulence-reducing phenotypic alterations during in vitro passage and support the need to study this organism in its clinical form.  (+info)

Detection of antibodies against Actinobacillus pleuropneumoniae serotypes 1, 2, 5 and 7 using the immunohistochemical staining. (6/272)

Whole cells of Actinobacillus pleuropneumoniae (A. pleuropneumoniae) serotype 1, 2, 5 or 7 attached to fibrins were fixed in 10% neutral buffered formalin and embedded in paraffin. The sections on a slide glass were stained by the avidin-biotin complex immunoperoxidase (ABC) method. Test sera were applied to sections as primary antibodies. The serum antibodies against A.pleuropneumoniae (serotypes 1, 2, 5 and 7) were measured by the ABC method and complement fixation (CF) test. There was good correlation between the ABC and CF tests. The present results indicate that the immunohistochemical staining is as useful as the CF test for the detection and quantification of antibody in swine sera.  (+info)

Characterization of apxIVA, a new RTX determinant of Actinobacillus pleuropneumoniae. (7/272)

A fourth type of RTX determinant was identified in Actinobacillus pleuropneumoniae and was designated apxIVA. When expressed in Escherichia coli, recombinant ApxIVA showed a weak haemolytic activity and co-haemolytic synergy with the sphingomyelinase (beta-toxin) of Staphylococcus aureus. These activities required the presence of an additional gene, ORF1, that is located immediately upstream of apxIVA. The apxIVA gene product could not be detected in A. pleuropneumoniae cultures grown under various conditions in vitro; however, pigs experimentally infected with A. pleuropneumoniae serotypes 1, 5 and 7 started to produce antibodies that reacted with recombinant ApxIVA 14 d post-infection, indicating that apxIVA is expressed in vivo. In addition, sera from pigs naturally and experimentally infected with any of the serotypes all reacted with recombinant ApxIVA. The apxIVA gene from the serotype 1 A. pleuropneumoniae type strain Shope 4074T encodes a protein with a predicted molecular mass of 202 kDa which has typical features of RTX proteins including hydrophobic domains in the N-terminal half and 24 glycine-rich nonapeptides in the C-terminal half that bind Ca2+. The glycine-rich nonapeptides are arranged in a modular structure and there is some variability in the number of modules in the ApxIVA proteins of different serotypes of A. pleuropneumoniae. The deduced amino acid sequences of the ApxIVA proteins have significant similarity with the Neisseria meningitidis iron-regulated RTX proteins FrpA and FrpC, and to a much lesser extent with other RTX proteins. The apxIVA gene could be detected in all A. pleuropneumoniae serotypes and seems to be species-specific. Although the precise role of this new RTX determinant in pathogenesis of porcine pleuropneumonia needs to be determined, apxIVA is the first in vivo induced toxin gene that has been described in A. pleuropneumoniae.  (+info)

Genomic relatedness among Actinobacillus pleuropneumoniae field strains of sterotypes 1 and 5 isolated from healthy and diseased pigs. (8/272)

Forty-four Actinobacillus pleuropneumoniae isolates recovered from both healthy and diseased pigs were characterized by random amplified polymorphic DNA analysis (RAPD), pulsed field gel electrophoresis (PFGE) and apx toxin gene typing. Nine RAPD types and 14 PFGE patterns were identified. No common RAPD or PFGE patterns were found between strains of serotype 1 and those of serotype 5. The RAPD analysis indicated that the 15 serotype 1 strains isolated from diseased pigs were assigned to 4 RAPD types, with 66% of strains characterized by the same RAPD type. By contrast, the 5 strains of serotype 1 isolated from healthy carriers were dispersed in 4 RAPD types. These data suggest that the diversity of strains isolated from healthy pigs could be higher than that of strains recovered from diseased pigs. In addition, all serotype 5 strains exhibited a unique RAPD type. Unlike RAPD, PFGE analysis allowed discrimination among isolates of serotype 1 and among those of serotype 5. All but 3 isolates showed the same apx genotype as their respective serotype reference strain. These data indicate that RAPD analysis is a valuable rapid tool for routine subtyping of strains of serotype 1. For strains of serotype 5, a combination of several typing methods, such as PFGE and apx gene typing, is needed to provide useful information on the molecular epidemiology of swine pleuropneumonia.  (+info)

TY - JOUR. T1 - Actinobacillus pleuropneumoniae serotypes in Hungary. AU - Sárközi, Rita. AU - Makrai, L.. AU - Fodor, L.. PY - 2018/9/1. Y1 - 2018/9/1. N2 - A total of 255 Actinobacillus pleuropneumoniae isolates were collected from 634 lung samples representing 70 swine herds in Hungary between January 2012 and June 2016. On the basis of the indirect haemagglutination test 77 independent strains were included in the evaluation after the elimination of duplicate or multiple serotypes from the same herd. In the case of 7 herds strains of two different serotypes were identified. Fourteen Hungarian A. pleuropneumoniae isolates from the culture collection of the Department of Microbiology and Infectious Diseases, isolated before 2012, were also included in the evaluation (one each from 12 herds and two each from two herds, where two serotypes occurred). Out of the altogether 91 A. pleuropneumoniae strains 72 strains belonged to biotype I and 19 strains could be allocated to biotype II. In ...
In Denmark porcine pleuropneumonia is most frequently caused by Actinobacillus pleuropneumoniae serotype 2 (60%). Isolation of A. pleuropneumoniae from nasal cavities or tonsils from carrier animals is complicated due to the mixed bacterial flora present. An immunomagnetic separation technique (IMS) using immunomagnetic beads (Dynabeads(R)) was developed for isolation of A. pleuropneumoniae serotype 2 from pure cultures and from heterogeneous suspensions. Different coating and washing procedures were evaluated in pure and mixed cultures using polyclonal (PAb) and monoclonal antibodies. The highest reisolation yield was achieved when the beads were coated with 1.5 mug PAb IgG/10(7) beads. After washing the beads for four times 9-24% of the bacteria could be reisolated depending on the amount of IgG attached to the beads and the number of beads used. The recovery was increased to 19-61% when only two washing steps were performed. The IMS was further evaluated using dilutions of A. pleuropneumoniae ...
article{176028, author = {Haesebrouck, Freddy and Chiers, Koen and Van Overbeke, Ingrid and Ducatelle, Richard}, issn = {0378-1135}, journal = {VETERINARY MICROBIOLOGY}, language = {eng}, number = {2-4}, pages = {239--249}, title = {Actinobacillus pleuropneumoniae infections in pigs: the role of virulence factors in pathogenesis and protection.}, volume = {58}, year = {1997 ...
Actinobacillus pleuropneumoniae serotype 3 UPF0263 protein APJL_1366 (APJL_1366) datasheet and description hight quality product and Backed by our Guarantee
Serotypes 3 and 8 of Actinobacillus pleuropneumoniae, the aetiological agent of porcine pleuropneumonia, have been reported to predominate in the UK. Direct serotyping of isolates of the organism is typically determined by the immunological reactivity of rabbit serum to its surface polysaccharides, but the method has limitations, for example, cross-reactions between serotypes 3, 6 and 8. This study describes the development of a serotype 3-specific PCR, based on the capsule locus, which can be used in a multiplex format with the organisms specific gene apxIV. The PCR test was evaluated on 266 strains of A pleuropneumoniae and 121 strains of other organisms, including all the major respiratory bacterial pathogens of pigs. The test was highly specific and sensitive and should be useful for differentiating strains of serotypes 3, 6 and 8, and in seroprevalence and epidemiological surveys in regions where serotype 3 is prevalent, such as the UK.. ...
Actinobacillus pleuropneumoniae is a Gram-negative bacterium and a member of the Pasteurellaceae family. This bacterium is the causative agent of porcine pleuropneumonia, which is a highly contagious respiratory disease causing important economical losses to the worldwide pig industry. It has been shown that A. pleuropneumoniae can form biofilms on abiotic surfaces (plastic and glass). Although in vitro models are extremely useful to gain information on biofilm formation, these models may not be representative of the conditions found at the mucosal surface of the host, which is the natural niche of A. pleuropneumoniae. In this paper, we describe a method to grow A. pleuropneumoniae biofilms on the SJPL cell line, which represents a biotic surface. A non-hemolytic, non-cytotoxic mutant of A. pleuropneumoniae was used in our assays and this allowed the SJPL cell monolayers to be exposed to A. pleuropneumoniae for longer periods. This resulted in the formation of biofilms on the cell monolayer after
Actinobacillus pleuropneumoniae (previously Haemophilus pleuropneumoniae), is a Gram-negative, facultative anaerobic, respiratory pathogen found in pigs. It was first reported in 1957, and was formally declared to be the causative agent of porcine pleuropneumonia in 1964. It was reclassified in 1983 after DNA studies showed it was more closely related to A. lignieresii. A. pleuropneumoniae is a nonmotile, Gram-negative, encapsulated coccobacillus bacterium found in the Pasteurellaceae family. It exhibits β-hemolysis activity, thus explaining its growth on chocolate or blood agar, but must be supplemented with NAD (V factor) to facilitate growth for one of its biological variants (biovar 1). As a facultative anaerobic pathogen, A. pleuropneumoniae may need CO2 to grow. Depending on the biovar, the bacteria may or may not be positive for urease; both biovars are positive for porphyrin. A. pleuropneumoniae was found to be the causative agent for up to 20% of all bacterial pneumonia cases in ...
Fifty randomly selected fattening pig herds were studied to investigate the epidemiological characteristics of infections with Actinobacillus pleuropneumoniae serovars 2, 3 and 9, and to identify risk factors for their within-herd seroprevalences. Information about 13 farm characteristics was obtained by means of a questionnaire and used to assess potential risk factors for the percentage of slaughter pigs with antibodies against each of the three serovars. The presence of antibodies was measured with an indirect ELISA. The median within-herd seroprevalence for serovar 2 was 58 per cent (range 0 to 100 per cent), for serovar 3, 53 per cent (range 10 to 95 per cent), and for serovar 9, 35 per cent (range 5 to 100 per cent). All but one farm tested positive for A pleuropneumoniae serovar 2, and all the farms were positive for A pleuropneumoniae serovars 3 and 9. There was a positive association (P<0.05) between each pair of serovars. The within-herd seroprevalence of serovar 2 was ...
Biomarkers of infection were screened for their possible role as evaluators of antibiotic treatment in an aerosol infection model of porcine pneumonia caused by Actinobacillus pleuropneumoniae (Ap). Following infection of 12 pigs, clinical signs of pneumonia developed within 20 h, whereafter the animals received a single dose of either danofloxacin (2.5 mg/kg) or tiamulin (10 mg/kg). To test the discriminative properties of the biomarkers, the dosage regimens were designed with an expected difference in therapeutic efficacy in favour of danofloxacin. Accordingly, the danofloxacin-treated pigs recovered clinically within 24h after treatment, whereas tiamulin-treated animals remained clinically ill until the end of the study, 48 h after treatment. A similar Picture was seen for the biomarkers of infection. During the infection period, plasma C-reactive protein (CRP), interleukin-6 and haptoglobin increased, whereas plasma zinc, ascorbic acid and alpha-tocopherol decreased. In the ...
Actinobacillus pleuropneumoniae ApaA protein: an antigenic membrane protein from Actinobacillus pleuropnemoniae homology to ABC transporters; amino acid sequence in first source
0004] It is commonly known how to produce the RTX-toxin ApxI by culturing Actinobacillus pleuropneumoniae in a culturing medium to which a calcium salt (i.e. a chemical compound, based on an acid, formed by replacing all or part of the hydrogen ions of the acid with one or more calcium ions) is added. In particular, EP 0 453 024 already describes such a method (see Example 2, paragraph 2 Purification and characterisation of hemolysin, subparagraph Methods). Note that ApxI used to be referred to as HLY (see Frey et al. in J Gen Microbiol. 1993 August; 139(8): 1723-8). From this EP patent it is known to add a calcium compound (CaCl2) to the medium. Indeed, in Microbiol Pathogenesis 37 (2004) 29-33 it is stated that transcriptional activity of the ApxI operon is enhanced by addition of calcium to the growth medium. This way, high levels of ApxI can be provided for. The medium should support the growth of APP bacteria. It is commonly known how to constitute a medium that supports growth of ...
Pleuropneumonia infectioasa a porcului (PIP), cauzata de Actinobacillus pleuropneumoniae (App), poate fi intalnita la porcii de toate varstele, inclusiv la mistreti, dar simptomele clinice cele mai frecvente sunt inregistrate la porcii in faza de finisare, in varsta de peste 12 saptamani. In formele clasice de boala animalele manifesta febra si simptome respiratorii, datorate leziunilor caracteristice de pneumonie hemoragico-necrotica sau pleuropneumonie fibrinoasa. Boala poate evolua supra-acut, fara semne clinice, animalele fiind gasite moarte, acut, mai ales in efectivele naive imunologic, cu pierderi prin mortalitate de 15-20%, sau sub-acut, cu mortalitate mai redusa dar variabila. In efectivele infectate endemic boala se cronicizeaza la animalele care au supravietuit, afectand starea lor de bine si producand o scadere a performantelor zootehnice. Porcii pot fi purtatori fara sa dezvolte vreun raspuns imun. Boala genereaza pierderi economice insemnate.. ...
MUNOZ, D; QUEZADA, M y RUIZ, A. Serological behaviour study of Actinobacillus pleuropneumoniae (App) in commercial swine herds from the central region of Chile. Arch. med. vet. [online]. 2008, vol.40, n.2, pp.147-153. ISSN 0301-732X. http://dx.doi.org/10.4067/S0301-732X2008000200006.. In Chile, there was only one existing study on App. This study was designed to determine the maternal immunity duration, the age of seroconversion and the apparent and true prevalence in animals from 7 swine commercial herds. 60 samples were taken per herd and divided into 10 serum samples from animals of 4, 6,10,14,18and21 weeks of age, which were analyzed by ELISA®. Out of the 420 samples, 134 were positive with 112 of them belonging to pigs under 10 weeks of age while only 22 were from animals over 10 weeks of age, which seroconverted presumably due to a natural infection. Regarding maternal immunity duration it was found that around the 10th week of age the animals lose their colostrum antibodies. In ...
Actinobacillus pleuropneumoniae ATCC ® 33590™ Designation: Femo TypeStrain=True Application: Characterization Respiratory research
Actinobacillus pleuropneumoniae, a Gram-negative, non-motile, facultatively anaerobic Pasteurellaceae, causes porcine pleuropneumonia, a highly contagious disease for which there is no effective vaccine. There are least twelve different serotypes, some of which produce no disease but others cause severe disease. Serotypes vary in different countries. Types 1, 5, 9, 11 and 12 are usually highly virulent and strains 3 and 6 are mild. The bacterium is carried in the tonsils and upper respiratory tract. It is transmitted short distances by droplet infection and only survives outside the pig for a few days.Actinobacillus pleuropneumoniae strain JL03 is an isolate of serotype 3 which is prevalent in China. Its genome is made up of a single circular chromosome encoding 2097 CDSs. It possesses a complete set of genes coding for enzymes of glycolysis, gluconeogenesis and non-oxidative pentose phosphate pathways. Genes coding for the key enzymes of the TCA cycle, citrate synthase, aconitase and isocitrate ...
ID ACTP7_1_PE100 STANDARD; PRT; 215 AA. AC ACTP7_1_PE100; B3GZU0; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE SubName: Full=Cytochrome c-type protein NrfB; (ACTP7_1.PE100). GN Name=nrfB; OrderedLocusNames=APP7_0100; OS ACTINOBACILLUS PLEUROPNEUMONIAE SEROVAR 7 STR. AP76. OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; OC Pasteurellaceae; Actinobacillus. OX NCBI_TaxID=537457; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACTP7_1.PE100. CC Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete genome. CC sequence. CC -!- ANNOTATIONS ORIGIN:B3GZU0_ACTP7 CC -!- GENE_FAMILY: HOG000278525 [ FAMILY / ALN / TREE ] DR UniProtKB/Swiss-Prot; B3GZU0; -. DR EMBL; CP001091; ACE60752.1; -; Genomic_DNA. DR RefSeq; YP_001967894.1; NC_010939.1. DR ProteinModelPortal; B3GZU0; -. DR STRING; B3GZU0; -. DR GeneID; 6397435; -. DR GenomeReviews; CP001091_GR; APP7_0100. DR ...
TY - JOUR. T1 - Enhancement of protective immune responses by oral vaccination with Saccharomyces cerevisiae expressing recombinant Actinobacillus pleuropneumoniae ApxIA or ApxIIA in mice. AU - Sung, Jae Shin. AU - Seung, Won Shin. AU - Mi, Lan Kang. AU - Deog, Yong Lee. AU - Yang, Moon Sik. AU - Jang, Yong Suk. AU - Han, Sang Yoo. PY - 2007/12. Y1 - 2007/12. N2 - We previously induced protective immune response by oral immunization with yeast expressing the ApxIIA antigen. The ApxI antigen is also an important factor in the protection against Actinobacillus pleuropneumoniae serotype 5 infection; therefore, the protective immunity in mice following oral immunization with Saccharomyces cerevisiae expressing either ApxIA (group C) or ApxIIA (group D) alone or both (group E) was compared with that in two control groups (group A and B). The immunogenicity of the rApxIA antigen derived from the yeast was confirmed by a high survival rate and an ApxIA-specific IgG antibody response (p , 0.01). The ...
Looking for Actinobacillus capsulatus? Find out information about Actinobacillus capsulatus. A genus of gram-negative, immotile and nonspore-forming, oval to rod-shaped, often pleomorphic bacteria which occur as parasites or pathogens in mammals ,... Explanation of Actinobacillus capsulatus
Pharmacokinetic-pharmacodynamic (PK/PD) integration and modelling were used to predict dosage schedules for florfenicol for two pig pneumonia pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida. Pharmacokinetic data were pooled for two bioequivalent products, pioneer and generic formulations, administered intramuscularly to pigs at a dose rate of 15 mg/kg. Antibacterial potency was determined in vitro as minimum inhibitory concentration (MIC) and Mutant Prevention Concentration in broth and pig serum, for six isolates of each organism. For both organisms and for both serum and broth MICs, average concentration:MIC ratios over 48 h were similar and exceeded 2.5:1 and times greater than MIC exceeded 35 h. From in vitro time-kill curves, PK/PD modelling established serum breakpoint values for the index AUC24h/MIC for three levels of inhibition of growth, bacteriostasis and 3 and 4log10 reductions in bacterial count; means were 25.7, 40.2 and 47.0 h, respectively, for P. multocida and 24.6,
Periodontitis is mankinds most common chronic inflammatory disease. One severe form of periodontitis is localized aggressive periodontitis (LAP), a condition to which individuals of African origin demonstrate an increased susceptibility. The main causative organism of this disease is Actinobacillus …
Shipping (test code: xtrnc) and handling (test code: xhand) fees are also applicable on each submission. External test price is subject to change. ...
SWISS-MODEL Repository entry for B3H073 (YQGF_ACTP7), Putative pre-16S rRNA nuclease. Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
SWISS-MODEL Repository entry for B3GZ69 (KTHY_ACTP7), Thymidylate kinase. Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Complete article is available online.. PDF version is available online.. Objective: To evaluate the duration of efficacy of a single dose of ceftiofur crystalline free acid sterile suspension (CCFA-SS) against clinical disease in grower pigs inoculated intratracheally with Actinobacillus pleuropneumoniae.. Materials and methods: One hundred and ninety male piglets were blocked by weight and randomly assigned to 19 pens of 10 animals each, with three pens randomly assigned to each of six treatments. Pigs were challenged with A pleuropneumoniae at 7 to 8 weeks old (Day 0). Groups 1 through 5 were treated with a single intramuscular dose of CCFA-SS (5 mg ceftiofur equivalents per kg body weight) on Days -13, -10, -7, -4, and -1, respectively. Group 6 pigs were challenged, untreated controls. A single pen of 10 unchallenged, untreated pigs acted as sentinels. The primary variable was removal rate (percent of pigs per pen that died or were euthanized because of severe illness by Day 9). Ancillary ...
Actinobacillus equulis: especie que se encuentra en la cavidad bucal y amígdalas del caballo y causa lesiones supurativas de los riñones y articulaciones de los cerdos y caballos y endocarditis en el cerdo ...
Biohazard level, growth media and temperature, gram stain, industrial applications and more information for Actinobacillus hominis.
Pourquier, P., Lesceu, S. Use of the ID Screen® APP indirect ELISA range for quick identification and serotyping of Actinobacillus pleuropneumoniae in domestic pigs. Poster presented at the 6th International Symposium on Emerging and Re-emerging Pig Diseases, June 2011, Madrid, Spain ...
Formulated to provide outstanding protection against the most common and virulent serotypes 1, 5 and 7. For prevention of pneumonia in pigs 4 weeks of age or older by infection with the prevalent serotypes of Actinobacillus pleuropneumoniae ...
With funding from Pork CRC, Australian scientists have developed a new one-shot vaccine delivery system against the endemic pig disease Actinobacillus pleuropneumoniae (APP).
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Investigation of the structure of lipid A from Actinobacillus actinomycetemcomitans strain Y 4 and human clinical isolate PO 1021-7
Actinobacillus pleuropneumoniae is the etiologic agent of porcine contagious pleuropneumonia, a significant disease that causes serious economic losses to the swine industry worldwide. Persistent infections caused by bacterial biofilms are recalcitrant to treat because of the particular drug resistance of biofilm-dwelling cells. TolC, a key component of multidrug efflux pumps, are responsible for multidrug resistance in many Gram-negative bacteria. In this study, we identified two TolC-like proteins, TolC1 and TolC2, in A. pleuropneumoniae. Deletion of tolC1, but not tolC2, caused a significant reduction in biofilm formation, as well as increased drug sensitivity of both planktonic and biofilm cells. The genetic-complementation of the tolC1 mutation restored the competent biofilm and drug resistance. Besides, biofilm formation was inhibited and drug sensitivity was increased by the addition of phenylalanine-arginine beta-naphthylamide (PAβN), a well-known efflux pump inhibitor (EPI), suggesting a role
Porcine pleuropneumonia, caused by Actinobacillus pleuropneumoniae, is a bacterial respiratory disease of swine. Acute outbreaks of the disease are often accompanied by high mortality and economic losses. As severe cases of the disease frequently require parenteral antibiotic treatment of the animals, the efficacy of a single, high dose of marbofloxacin was compared to a three-time application of a dose of enrofloxacin under experimental conditions. A blinded, controlled, randomized and blocked dose confirmation study was conducted to test the efficacy and safety of a single dose of 8 mg/kg marbofloxacin (160 mg/ml, Forcyl® Swine, Vetoquinol SA, France) to treat acute porcine pleuropneumonia after experimental aerosol inoculation of pigs with A. pleuropneumoniae serotype 2. The results were compared to a three consecutive day treatment of 2.5 mg/kg enrofloxacin and a mock (saline) treatment. Criteria for the assessment of efficacy were severity of lung lesions, bacteriological cure and the course of
TY - JOUR. T1 - Cell surface-associated enolase in Actinobacillus actinomycetemcomitans. AU - Hara, Hiroaki. AU - Ohta, Hiroyuki. AU - Inoue, Tetsuyoshi. AU - Ohashi, Toshio. AU - Takashiba, Shogo. AU - Murayama, Yoji. AU - Fukui, Kazuhiro. PY - 2000. Y1 - 2000. N2 - Cell surface-associated materials of Actinobacillus actinomycetemcomitans were extracted by a short incubation of the cell suspension in a Tris-buffered saline in the presence and absence of a restriction enzyme, EcoRI. The supernatants (which we termed EcoRI extract and surface extract, respectively) contained a number of extracellularly released proteins. Of these proteins, four major proteins were identified by N-terminal sequencing to be the 34 and 39 kDa outer membrane proteins, the GroEL-like protein, and a 47 kDa protein homologous to Haemophilus influenzae enolase. Enolase activity was found in the extracts and its relative amount of activity in the EcoRI extract from a culture of the mid-exponential growth phase was ...
Two previous studies have observed natural transformation in A. actinomycetemcomitans. Tøonjum et al. (30) used a broth-based method and identified two naturally competent strains among five study strains of A. actinomycetemcomitans with transformation frequencies of 1.3 × 10−3 and 6.2 × 10−5. In our present study, we identified a single highly competent A. actinomycetemcomitans strain among 17 strains examined. Although this is an apparently lower prevalence of naturally competent A. actinomycetemcomitans strains than was reported by Tøonjum et al., the transformation frequencies reported in this study were similar.. Sato et al. (23) generated transposon insertional mutants from the A. actinomycetemcomitans strain Y4 by natural transformation. The transformation was performed with broth-cultured exponential-phase A. actinomycetemcomitans cells. However, strain Y4 was not transformable in our study. While the loss of competence is sometimes a consequence of laboratory propagation, it is ...
0165] (1) Wilson M, Henderson, B. Virulence factors of A. actinomycetemcomitans revenant to the pathogenesis of inflammatory periodontal diseases. FEMS 1995:17:365-379. [0166] (2) Nowotny A, Behling U H, Hammond B, et al. Release of toxic microvesicles by Actinobacillus actinomycetemcomitans. Infect Immun 1982:37:151-154. [0167] (3) Kaplan J B, Perry M B, MacLean L L, Furgang D, Wilson M E, Fine D H. Structural and genetic analyses of 0 polysaccharide from Actinobacillus actinomycetemcomitans serotype f. Infect Immun 2001:69:5375-5384. [0168] (4) Rosan B, Slots J, Lamont R J, Listgarten M A, Nelson G M. Actinobacillus actinomycetemcomitans fimbriae. Oral Microbiol Immunol 1988:3:58-63. [0169] (5) Inouye T, Ohta H, Kokeguchi S, Fukui K, Kato K. Colonial variation and fimbriation of Actinobacillus actinomycetemcomitans. FEMS microbiology letters 1990: 57: 13-17. [0170] (6) Kaplan J B, Schreiner H C, Furgang D, Fine D H. Population structure and genetic diversity of Actinobacillus ...
A little over two years ago, we commented on a general rise in the frequency of Actinobacillus suis (A. suis) isolation from our swine tissue submission cases, and wondered if it was related to the increased porcine circovirus type 2 (PCV2) activity (National Hog Farmer North American Preview, June 6, 2008).
Structures of the antigenic O-polysaccharides of lipopolysaccharides produced by Actinobacillus actinomycetemcomitans serotypes a, c, d and e
The complete nucleotide sequence of a 7.7kb mobilisable plasmid (pM3446F), isolated from a florfenicol resistant isolate of Actinobacillus pleuropneumoniae, showed extended similarity to plasmids found in other members of the Pasteurellaceae containing the floR gene as well as replication and mobilisation genes. Mobilisation into other Pasteurellaceae species confirmed that this plasmid can be transferred horizontally ...
Fingerprint Dive into the research topics of Isolation and characterization of the dnaKJ operon from Actinobacillus actinomycetemcomitans. Together they form a unique fingerprint. ...
ID C9R3L9_AGGAD Unreviewed; 404 AA. AC C9R3L9; DT 24-NOV-2009, integrated into UniProtKB/TrEMBL. DT 24-NOV-2009, sequence version 1. DT 25-OCT-2017, entry version 39. DE SubName: Full=Molybdopterin molybdenumtransferase {ECO:0000313,EMBL:ACX82405.1}; GN OrderedLocusNames=D11S_1018 {ECO:0000313,EMBL:ACX82405.1}; OS Aggregatibacter actinomycetemcomitans serotype C (strain D11S-1) OS (Actinobacillus actinomycetemcomitans). OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; OC Pasteurellaceae; Aggregatibacter. OX NCBI_TaxID=668336 {ECO:0000313,EMBL:ACX82405.1, ECO:0000313,Proteomes:UP000002569}; RN [1] {ECO:0000313,EMBL:ACX82405.1, ECO:0000313,Proteomes:UP000002569} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=D11S-1 {ECO:0000313,EMBL:ACX82405.1, RC ECO:0000313,Proteomes:UP000002569}; RX PubMed=19820097; DOI=10.1128/JB.01203-09; RA Chen C., Kittichotirat W., Si Y., Bumgarner R.; RT Genome sequence of Aggregatibacter actinomycetemcomitans serotype c RT strain D11S-1.; ...
Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR ...
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Astăzi, conform manualului Bergey, în genul Actinobacillus, în afară de A. lignieresii şi A. suis, care produc bolile numite actinobaciloze, sunt alăturate şi alte 16 specii de bacterii (1). Acestea însă fie că produc entităţi diferite ca patogenie şi manifestări anatomoclinice, din care cauză poartă şi denumiri diferite, fie că produc nişte infecţii, în general rare, localizate şi manifestate altfel decât boala limbii de lemn produsă de A.lignieresii, fie că sunt prezente ca simpli germeni oportunişti, fără un rol patologic bine precizat. Dintre acestea, patologia veterinară este interesată de:. - A.pleuropneumoniae, care produce pleuropneumonia infecţioasă a porcului, ...
Monoclonal antibody against Aggregatibacter actinomycetemcomitans serotype b expressed by for use in Western Blot against gram-negative bacteria
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LIU, Qiong et al. Construction and immunogenicity of a ΔapxIC/ompP2 mutant of Actinobacillus pleuropneumonias and Haemophilus parasuis. Onderstepoort j. vet. res. [online]. 2013, vol.80, n.1, pp.1-6. ISSN 2219-0635.. The apxIC genes of the Actinobacillus pleuropneumoniae serovar 5 (SC-1), encoding the ApxI-activating proteins, was deleted by a method involving sucrose counter-selection. In this study, a mutant strain of A. pleuropneumoniae (SC-1) was constructed and named AapxIC/ ompP2. The mutant strain contained foreign DNA in the deletion site of ompP2 gene of Haemophilus parasuis. It showed no haemolytic activity and lower virulence of cytotoxicity in mice compared with the parent strain, and its safety and immunogenicity were also evaluated in mice. The LD50 data shown that the mutant strain was attenuated 30-fold, compared with the parent strain (LD50 of the mutant strain and parent strain in mice were determined to be 1.0 x 107 CFU and 3.5 x 105 CFU respectively). The mutant strain that ...
TY - JOUR. T1 - Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages in humans.. AU - Nakagawa, S.. AU - Machida, Y.. AU - Nakagawa, Taneaki. AU - Fujii, H.. AU - Yamada, S.. AU - Takazoe, I.. AU - Okuda, K.. PY - 1994/1. Y1 - 1994/1. N2 - This study examined the serum IgG and IgM responses against Porphyromonas gingivalis and 3 serotypes of Actinobacillus actinomycetemcomitans, and the correlations of these responses with age and homologous infection. A total of 90 individuals were included in this study: 40 subjects with gingivitis, 40 periodontally healthy subjects, and 10 adult periodontitis subjects. The subjects in the gingivitis and periodontally healthy groups were divided into 4 stages based on their physiological age: early childhood, school age, puberty, and adult. In the gingivitis group, there was a positive correlation between increase in age and increase in serum IgG antibody levels against P. gingivalis until ...
Aggregatibacter (Actinobacillus) actinomycetemcomitans is a bacterium mainly associated with aggressive forms of periodontitis. Among its virulence factors, a leukotoxin is suggested to play an important role in the pathogenicity. Periodontal infections with strains producing high levels of the leukotoxin are strongly associated with severe disease. Leukotoxin selectively kills human leukocytes and can disrupt the local defense mechanisms. Previous studies examining the role of the leukotoxin in host-parasite interactions have mainly focused on polymorphonuclear leukocytes (PMNs). In the inflamed periodontium, macrophages play a significant role in the regulation of the inflammatory reactions and the tissue breakdown and remodeling.. Thus, the aim of this dissertation was to investigate death mechanisms of human macrophages exposed to leukotoxin.. Human lymphocytes, PMNs, and monocytes/macrophages isolated from venous blood were exposed to purified leukotoxin or live A. actinomycetemcomitans ...
Aggregatibacter actinomycetemcomitans ATCC ® 700685D-5™ Designation: Genomic DNA from Aggregatibacter actinomycetemcomitans strain HK1651 TypeStrain=False Application:
Structural studies of the O-chain of the phenol-phase soluble lipopolysaccharide from Haemophilus pleuropneumoniae serotype 2: Biochem.Cell Biol.
Aggregatibacter actinomycetemcomitans (A.a) serotypes may add some important information of the pathogenetic background of periodontal infections. (adsbygoogle = window.adsbygoogle ,, []).push({}); When grown in culture, these form small colonies, approximately 0.5-1.0 mm in diameter. The cytotoxin produced by, Almost all strains of A. actinomycetemcomitans have these vesicles. 2008 Apr 1;10(5):489-96. The results of the study showed that these antibodies might contribute to limit the systemic effects of the infection. Ltx B and Ltx D are involved in transporting the toxin to the surface of the cell while Ltx C post-transitionally activates the toxin. The most common bacteria involved in periodontal pathologies of young individuals and in cases of refractory adult periodontitis is Aggregatibacter actinomycetemcomitans. This genus includes Gram-negative, non-motile, facultatively anaerobic rods or coccobacilli that were previously known as Haemophilus. The active subunit, CdtB, exhibits DNase I ...
TY - GEN. T1 - Experimental and modelling studies of the bioconversion of glycerol to succinic acid by actinobacillus succinogenes. AU - Vlysidis, Anestis. AU - Du, Chenyu. AU - Webb, Colin. AU - Theodoropoulos, Constantinos. PY - 2008/12/1. Y1 - 2008/12/1. N2 - An unstructured kinetic model for the growth of Actinobacillus succinogenes on glycerol as the only carbon source is proposed in this study. The model describes cell growth considering both substrate and product inhibition. and its parameters are estimated by fitting the model predictions to experimental data. Substrate consumption and product formation rates are described by the Luedeking-Piret model. The main product of the process is succinic acid while by-products like acetate, formate and ethanol have very low concentrations. The main environmental factors that affect the bioprocess were examined and optimum conditions in terms of yield, final succinic acid concentration and productivity were evaluated by a factorial experimental ...
Succinic acid (SA) is poised to become a significant building-block or platform chemical in the bio-based economy. Of the microbial strains that show promise for biological SA production, the wild-type bacterium Actinobacillus succinogenes is one of the top-contenders. While strides have been made towards understanding the behaviour of the organism and developing the fundamentals for an industrial process based on the organism, there is still a large scope of research required and a multitude of challenges to be addressed. In particular, an improved understanding of the metabolism of the organism under favourable biofilm conditions is required and its potential as a microbial host in a biorefinery setting needs to be established. Therefore, the aim of this thesis is to develop a fundamental understanding of the central metabolism of the organism under biofilm conditions on relevant substrates, and to determine its performance as a SA producer on scalable biorefinery streams. Continuous operation ...
TY - JOUR. T1 - Towards an understanding of equine pleuropneumonia. T2 - Factors relevant for control. AU - Racklyeft, D. J.. AU - Raidal, S.. AU - Love, D. N.. PY - 2000/5. Y1 - 2000/5. N2 - Objective: To review relevant literature on factors associated with the development of equine pleuropneumonia Design: A review of the literature using a range of databases including Current Contents, Medline, ChemAbstracts, Biological Abstracts and CAB and a comprehensive search strategy which involved use of keywords, author and subject category searches. Additional sources included review of articles cited by key accumulated references. Results: Since the early years of this century, many of the gaps in our knowledge of the pathogenesis of this disease have been filled. We now know that equine pleuropneumonia results from contamination of the lower respiratory tract with bacteria similar to the normal oropharyngeal microbiota of the horse and that transportation of any mode, especially over long ...
This study evaluated the effect of oral lactobacilli on the cytotoxicity and cytokine release from peripheral blood mononuclear cells (PBMCs) when exposed to Aggregatibacter actinomycetemcomitans subtypes in vitro. The supernatants and cell wall extracts (CWEs) of eight A. actinomycetemcomitans strains, representing different subtypes, and three Lactobacillus strains were used. The PBMCs from six blood donors were exposed to supernatants and CWEs of A. actinomycetemcomitans or Lactobacillus strains alone or combinations and untreated cells as control. The cytotoxicity was determined by trypan blue exclusion method and IL-1β secretion by ELISA. TNF-α, IL-6, and IL-8 secretions were measured using Bioplex Multiplex Immunoassay. Supernatants or CWEs from all bacterial strains showed cytotoxicity and IL-1β secretion and the subtypes of A. actinomycetemcomitans showed generally a significantly higher effect on PBMCs than that of the Lactobacillus strains. Two highly toxic A. actinomycetemcomitans strains
The ability to selectively target specific biofilm species with antimicrobials would enable control over biofilm consortium composition, with medical applications in treatment of infections on mucosal surfaces that are colonized by a mixture of beneficial and pathogenic microorganisms. We functionalized a genetically engineered multimeric protein with both a targeting moiety (biotin) and either a fluorophore or a photosensitizer (SnCe6). Biofilm microcolonies of Aggregatibacter actinomycetemcomitans, a periodontal pathogen, were targeted with the multifunctional dodecamer. Streptavidin was used to couple biotinylated dodecamer to a biotinylated anti-A. actinomycetemcomitans antibody. This modular targeting approach enabled us to increase the loading of photosensitizer onto the cells by a cycle of amplification. Scanning laser confocal microscopy was used to characterize transport of fluorescently tagged dodecamer into the microcolonies and targeting of the cells with biotin-labeled, ...
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Adolescent; Aggregatibacter actinomycetemcomitans; Bacterial Toxins; Cohort Studies; Cross-Sectional Studies; DNA, Bacterial; Disease Progression; Ghana; Humans; Pasteurellaceae Infections; Periodontal Diseases ...
Aggregatibacter actinomycetemcomitans GroEL Protein Promotes Conversion of Human CD4 T Cells into IFNγ IL10 Producing Tbet Th1 Cells. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Importance of Streptococci in the reproduction disorders OF THE MARE. NEW DATAS. The authors described the important intervention of Strepto coccus zooepidemicus, equi, equisimilis and uberis in the bacterial disorders of reproduction (fertility, endometritis) and causes of abortion. The principal bacterial pathogens causing disorders are : Streptococci, Escherichia coli, Klebsiella pneumoniae, Actinobacillus equuli, Salmonella typhimurium, Pseudomonas aeruginosa. The Streptococcal diseases are found in over 50 per cent of confirmed cases of bacterial disorders of reproduction. The bacterial contamination access to the vagina and uterus of the mares, often, during the breeding of foaling. The bacteriological controls of mares and stallions are necessary before breeding and the research of several bacterial organisms is obligatory ...
Learn about the veterinary topic of Pleuropneumonia in Horses. Find specific details on this topic and related topics from the Merck Vet Manual.
TSBV agar is an enriched selective medium used for the isolation of Aggregatibacter actinomycetemcomitans from clinical specimens. The nutritive base consists of casein, soy peptone, and yeast extract. Sodium chloride is added to maintain osmotic equilibrium of the media. Serum is included to enhance the recovery of Aggregatibacter actinomycetemcomitans. The selective agents include bacitracin and vancomycin at concentrations that inhibit most gram-positive and gram-negative anaerobes. This media is prepared, dispensed, and packaged under oxygen-free conditions to prevent the formation of oxidized products prior to use.. ...
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A Periodontite Agressiva (PA), que atualmente pertence ao grupo das Periodontites est gios 3 e 4, distingue-se dos demais tipos de doen a periodontal por seu in cio precoce, agrega o familiar dos casos e por afetar pacientes sistemicamente saud veis. Al m disso, pode ser subclassificada em duas formas, localizada (PAL) e generalizada (PAG), em fun o de sua extens o. Muitas vezes, os dep sitos de biofilme bacteriano s o desproporcionais quantidade de destrui o ssea e perda de inser o que o paciente apresenta, independente da subclassifica o. O microrganismo mais relacionado etiopatog nese da doen a o Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans), incluindo os seus principais sorotipos a, b e c, amplamente estudados. Associado a estas condi es, A. actinomycetemcomitans apresenta alguns fatores de virul ncia como uma leucotoxina, principalmente ligada ao sorotipo b - clone JP2 (que altamente leucot xico) e prote nas de membrana externa (OMPs), especialmente Omp29. A resposta de ...
Immunological detection of antigens of Aggregatibacter actinomycetemcomitans, P intermedia, P gingivalisusing antibodies (ELISA ...
"EHV-1 Congenital Infection and Concurrent Actinobacillus Equuli Septicemia in a Standardbred Neonatal Foal: Clinical, ... "Facial Cellulitis Due to Actinobacillus Equuli Infection in a Neonatal Foal." Veterinary Record 162.11 (2008): 347-349. Web. ... "Septicemia and Peritonitis Due to Actinobacillus Equuli Infection in an Adult Horse." Veterinary Pathology 38.2 (2001): 230-232 ... Infections in swine are more common in European countries compared to the North American Countries. Infections in the United ...
Actinobacillus pleuropneumonia and Salmonella infections in pigs. Prior to the introduction of vaccination with material from ... "Development of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae infection". Vaccine. 24 (49-50): 7226-7237. doi: ... Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or ... They can also mitigate the severity of infection, resulting in a lower mortality rate, lower morbidity, faster recovery from ...
... and Streptococcus suis or Actinobacillus pleuropneumoniae infection. Antibiotics such as ceftiofur, gentamicin, and ... Actinobacillus suis is a beta-haemolytic, Gram-negative bacterium of the family Pasteurellaceae. The bacterium has many strains ... Type strain of Actinobacillus suis at BacDive - the Bacterial Diversity Metadatabase (Articles with 'species' microformats, ... Affected piglets can develop septicaemia, multifocal infections, and respiratory signs, and may die. Adult pigs may show signs ...
In 1995, Its infections cost the U.S. economy about $30 million. Such losses usually result from medication and veterinary ... Actinobacillus pleuropneumoniae was found to be the causative agent for up to 20% of all bacterial pneumonia cases in swine. ... Actinobacillus pleuropneumoniae is a nonmotile, Gram-negative, encapsulated coccobacillus bacterium found in the family ... Overcrowding in pigpens, co-infections of other respiratory pathogens, and unusual stress all contribute to the spread of the ...
The infection is most commonly caused by abrasions on different soft tissues through which the bacteria, Actinobacillus ... One of the most common forms seen by veterinarians is mouth actinobacillosis of cattle, due to Actinobacillus lignieresii. The ... Actinobacillosis is a zoonotic disease caused by Actinobacillus. It is more commonly associated with animals than with humans. ... actinomycosis Actinobacillus suis "Merck Veterinary Manual". "Dorlands Medical Dictionary:actinobacillosis".[permanent dead ...
All infections were cured. Intervet developed cefquinome (Cobactan) to treat bovine respiratory disease, the most common ... Actinobacillus pleuropneumoniae, and Streptococcus suis. Mastitis-metritis-agalactia syndrome involved with E. coli, ... For pigs, it is used to treat bacterial infections of the lungs and respiratory tract caused by P. multocida, Haemophilus ... To prevent the claimed infections in piglets, attention should be paid to hygiene and ventilation, and overcrowding should be ...
... cystic fibrosis or HIV infection. Staphylococcus aureus is usually the organism that causes the infection, however it can also ... and Actinobacillus lignieresii or other species of bacteria. The anatomic structure of its lesion is similar to that of ... mykes = fungus). In 1919 the bacterial origin of the infection was discovered. James, William D.; Berger, Timothy G.; et al. ( ... Botryomycosis; is a rare chronic granulomatous bacterial infection that affects the skin, and sometimes the viscera.: 255 ...
Sneath, P. H. A.; Stevens, M. (1990). "Actinobacillus rossii sp. nov., Actinobacillus seminis sp. nov., nom. rev., Pasteurella ... Pasteurella bettyae is a bacterium associated with human Bartholin gland abscess and finger infections. ...
In addition to valvular infections in the heart, they can also produce other infections, such as bacteremia, abscess, ... HACEK originally referred to Haemophilus parainfluenzae, Haemophilus aphrophilus, Actinobacillus actinomycetemcomitans, ... 1], eMedicine, HACEK organism infection. June 2005. (Articles with short description, Short description matches Wikidata, ... which is an inflammation of the heart due to bacterial infection. HACEK is an abbreviation of the initials of the genera of ...
Infection and Immunity. 69 (12): 7610-5. doi:10.1128/iai.69.12.7610-7615.2001. PMC 98854. PMID 11705940. Malone T, Blumenthal ... "Inactivation of DNA adenine methyltransferase alters virulence factors in Actinobacillus actinomycetemcomitans". Oral ...
Polyps or mucus can obstruct the nasopharynx, as can congestion due to an upper respiratory infection. The auditory tube, which ... The HACEK organisms (Haemophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, Kingella ... and share an enhanced capacity to produce endocardial infections, especially in young children. Fusobacterium is a pathogen. ...
It has also been isolated from actinomycotic lesions (mixed infection with certain Actinomyces species, in particular A. ... It was reclassified as Actinobacillus actinomycetemcomitans by Topley & Wilson (1929) and as Haemophilus actinomycetemcomitans ... Jorth P, Trivedi U, Rumbaugh K, Whiteley M (November 2013). "Probing bacterial metabolism during infection using high- ... Less frequently, A. actinomycetemcomitans is associated with nonoral infections such as endocarditis. Its role in aggressive ...
Fives-Taylor PM, Meyer DH, Mintz KP, Brissette C (June 1999). "Virulence factors of Actinobacillus actinomycetemcomitans". ... Clinical Microbiology and Infection. 7 (4): 213-7. doi:10.1046/j.1469-0691.2001.00210.x. PMID 11422244. Genco RJ, Zambon JJ, ... Zambon JJ, Christersson LA, Slots J (December 1983). "Actinobacillus actinomycetemcomitans in human periodontal disease. ... High levels of Aggregatibacter (or Actinobacillus) actinomycetemcomitans and, in some populations, Porphyromonas gingivalis. ...
"Comparison of Two Selective Media for Actinobacillus actinomycetemcomitans." J Clin Microbiol 1986;24:636-638. Fryman A, ... that substantiated aggressive periodontitis as a bona fide infection, rather than merely a degenerative disorder. Dental ... Slots is responsible for discovering the role of Aggregatibacter actinomycetemcomitans (previously Actinobacillus ...
... actinobacillus infections MeSH C01.252.400.700.030.178 - actinobacillosis MeSH C01.252.400.700.433 - haemophilus infections ... bacteroides infections MeSH C01.252.400.126 - bartonellaceae infections MeSH C01.252.400.126.100 - bartonella infections MeSH ... moraxellaceae infections MeSH C01.252.400.560.022 - acinetobacter infections MeSH C01.252.400.610 - mycoplasmatales infections ... salmonella infections, animal MeSH C01.252.400.310.821.873 - typhoid fever MeSH C01.252.400.310.850 - serratia infections MeSH ...
"HACEK Group Infections: Overview - eMedicine Infectious Diseases". Retrieved 2009-03-17. v t e (Articles with short description ... Norskov-Lauritsen N, Kilian M. (2006). "Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, ...
... may be useful for treating and preventing biofilm-associated infections caused by poly-N-acetylglucosamine- ... Kaplan JB, Ragunath C, Ramasubbu N, Fine DH (August 2003). "Detachment of Actinobacillus actinomycetemcomitans biofilm cells by ... Kaplan JB, Meyenhofer MF, Fine DH (2003). "Biofilm growth and detachment of Actinobacillus actinomycetemcomitans". J. Bacteriol ... a biofilm-releasing glycoside hydrolase from the periodontopathogen Actinobacillus actinomycetemcomitans". J. Mol. Biol. 349 (3 ...
Infection has been shown to have high prevalence in the autumn and winter months. K.kingae infections are rare in adults, but ... Actinobacillus, Cardiobacterium, Eikenella, and Kingella organisms: a retrospective multicenter evaluation". J. Clin. Microbiol ... Poor oral hygiene, pharyngitis, and mucosal ulceration are also predisposing factors for infection. The infection can occur in ... The infection rate is poorly documented, thus the illness tends to go underdiagnosed. K. kingae can be transmitted person to ...
With the consistent and complete removal of biofilm, the infection can be arrested and healthy periodontium can be achieved. ... These bacteria include Porphyromonas gingivalis, Prevotella intermedia, and Actinobacillus actinomycetemcomitans. Healthy ...
... viral infection, and bacterial infection. As a result, sulfatide is associated with, able to bind to, and/or is present in ... Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae are pathogens that cause respiratory disease in swine. Haemophilus ... However, sulfatide has little function in HIV-1 infection of CD4+ cells. The binding of gp120 to GalCer has the ability to ... Sulfatide has been shown to play a role or have some association with several diseases and infections. This includes diabetes ...
"First description of an Anaerobiospirillum succiniciproducens prosthetic joint infection". New Microbes and New Infections. 18 ... Henderson B, Ward JM, Ready D (October 2010). "Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* ... It can be potentially lethal to humans, but infections are rare. † Archaeoacanthocircus angustiannulatus Kozur, Moix & Ozsvárt ... Norskov-Lauritsen N, Kilian M (2006). "Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, ...
... urinary tract infections, catheter infections, middle-ear infections, formation of dental plaque, gingivitis, coating contact ... Kaplan JB, Ragunath C, Ramasubbu N, Fine DH (August 2003). "Detachment of Actinobacillus actinomycetemcomitans biofilm cells by ... Examples of such infections include chronic wounds, chronic otitis media, chronic prostatitis and chronic lung infections in ... Biofilms of fungal origin are important aspects of human infection and fungal pathogenicity, as the fungal infection is more ...
The question then became how exposure to the caterpillars produced these non-specific bacterial infections of the affected ... Actinobacillus encephalitis. MRLS was observed in mares of all breeds and ages. Early and late fetal losses were observed ... Mares which aborted are treated with broad-spectrum antibiotics to avoid bacterial infections. The foals born from mares ... Reviewing the speed with which ETCs produced late-term abortions in 2002 experiments, the nonspecific bacterial infections in ...
Adequate plaque control is important in ensuring long-term results from the procedure, and if post-operative infection control ... CO2 laser Diode laser It has been suggested that lasers can give a substantial reduction in bacteria such as Actinobacillus ...
Categories: Actinobacillus Infections Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine.. Mamm ...
Early Detection of Infection in Pigs through an Online Monitoring System. Transboundary and Emerging Diseases 64(2): 364-373. ... and Actinobacillus pleuropneumoniae (A. pleuropneumoniae) in Young Pigs. PlosOne, http://dx.doi.org/10.1371/journal.pone. ... Enriched Housing Reduces Disease Susceptibility to Co-Infection with Porcine Reproductive and Respiratory Virus (PRRSV) ...
... are produced during the most early stage of an infection. The activities of these cytokines have been studied extensively in ... of early cytokines in pneumonia in swine came from experimental infections with Mycoplasma hyopneumoniae and Actinobacillus ... In further studies, we will use more specific strategies to dissect the role of cytokines during viral infections. ... are produced during the most early stage of an infection. The activities of these cytokines have been studied extensively in ...
This generally has a detrimental effect on the host and is attributed to many chronic infections which poses a therapeutic ... and interspecies regulation of gene expression by Actinobacillus actinomycetemcomitans LuxS," Infection and Immunity, vol. 69, ... J. Frias, E. Olle, and M. Alsina, "Periodontal pathogens produce quorum sensing signal molecules," Infection and Immunity, vol ... This generally has a detrimental effect on the host and is attributed to many chronic infections which poses a therapeutic ...
Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model ... Establishment and comparison of Actinobacillus pleuropneumoniae experimental infection model in mice and piglets. Microb Pathog ... Actinobacillus pleuropneumoniae; deletion mutation; apxIBD gene; pnp gene; virulence Figure. *. Fig. 1. PCR analysis of the ... Li T, Zhang Q, Wang R, Zhang S, Pei J, Li Y, Li L, Zhou R. The roles of flp1 and tadD in Actinobacillus pleuropneumoniae pilus ...
... indicative of bacterial infections caused by Actinobacillus pleuropneumoniae and Haemophilus parasuis. A whole range of ... PMWS - Controlling Secondary Infections By David G S Burch BVetMed MRCVS, Octagon Services Ltd - Apart from a high mortality, ... It appears to be spreading like an infection with East Anglia being the worst hit, accounting for 88% of the cases in early ... Lymph nodes are enlarged, which is often the case with infection but there is depletion of the normal lymphoid cells, which ...
Dive into the research topics of Relative avidity of serum immunoglobulin G antibody for the fimbria antigen of Actinobacillus ... Relative avidity of serum immunoglobulin G antibody for the fimbria antigen of Actinobacillus actinomycetemcomitans in patients ...
Actinobacillus pleuropneumoniae Infection. Internal Control Genes. Gene Symbol Gene Name Application Scope Accession Number ... Validation of putative reference genes for qRT-PCR normalization in tissues and blood from pigs infected with Actinobacillus ...
These consortiums can colonize a variety of surfaces, such as host tissues, dentures, and catheters, resulting in infections ... Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella spp., and Kingella spp. To sum up, infections ... Although the number of anaerobic species involved in infections is lower, compared with the aerobic, and the infections are ... Chapter 1-1. Anaerobic infections (General): Epidemiology of anaerobic infections. J. Infect. Chemother. 2011, 17, 4-12. [ ...
Meningococcal Infections 1 0 Actinobacillus Infections 1 0 Adenocarcinoma 1 0 Behcet Syndrome 1 0 ...
Actinobacillus infection (disorder). Code System Preferred Concept Name. Actinobacillus infection (disorder). Concept Status. ...
Infections with bacteria of the genus ACTINOBACILLUS.. Annotation:. do not confuse with ACTINOBACILLOSIS, a specific vet dis ... Infections à Actinobacillus Entry term(s):. Actinobacillus Infection. Infection, Actinobacillus. Infections, Actinobacillus. ... Infections with bacteria of the genus ACTINOBACILLUS. Preferred term. Actinobacillus Infections Entry term(s). Actinobacillus ... Actinobacillus Infections - Preferred Concept UI. M0000282. Scope note. ...
Infection and immunity. *1984. *Corpus ID: 41340140. Longitudinal clinical and microbiological monitoring of subjects with ... Actinobacillus pleuropneumoniae 1 Ab:PrThr:Pt:Ser:Ord. Known as: Actinobacillus pleuropneumoniae 1 Antibody:Presence or ... Actinobacillus pleuropneumoniae vaccines: from bacterins to new insights into vaccination strategies. *Mahendrasingh Ramjeet, ... The objective of the study was to identify risk factors for reintroduction of Actinobacillus pleuopneumoniae and Mycoplasma… ...
We conclude that 11 out of the 13 up-regulated M. osloensis genes are infection specific. Distribution of these identified ... reticulatum and are hence infection specific. Mutational analysis on genes of protein-disulfide isomerase (dsbC) and ubiS ... Thirteen M. osloensis genes were identified to be up-regulated post infection in D. reticulatum. Compared to the in vitro ... Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Appl ...
Actinobacillus Infections 6% * Dimethyl Sulfoxide 6% * Border disease virus 6% * dimethylacetamide 6% ...
In: Infection and immunity, Vol. 56, No. 5, 1988, p. 1162-1166.. Research output: Contribution to journal › Article › peer- ... The purified leukotoxin of Actinobacillus actinomycetemcomitans kills human leukemic cell lines (e.g., HL-60, U937, and KG-1) ... N2 - The purified leukotoxin of Actinobacillus actinomycetemcomitans kills human leukemic cell lines (e.g., HL-60, U937, and KG ... AB - The purified leukotoxin of Actinobacillus actinomycetemcomitans kills human leukemic cell lines (e.g., HL-60, U937, and KG ...
... lavage fluid reveals potential biomarkers corresponding to resistance to Actinobacillus pleuropneumoniae infection Dennis ... Veterinary Research, a journal on Animal Infection. ISSN: 0928-4249 - eISSN: 1297-9716. © INRA / EDP Sciences ...
Positive effects of vaccination against Actinobacillus pleuropneumonia (Ap) and optimised co-infection vaccination measured on ... Prevalence of Mycoplasma hyopneumoniae early infections in pigs The aim of this survey was to describe the prevalence of Mhyo ... Current situation of Actinobacillus pleuropneumonia in Spain according to lung lesions scored at slaughterhouse using the Ceva ... A special attention was paid to the early infections in young piglets at- and early after weaning. At the same time the... ...
"Actinobacillus Pleuropneumoniae: Pathobiology and Pathogenesis of Infection." Microbes and Infection, vol. 4, no. 2, 2002, pp. ... "Actinobacillus Pleuropneumoniae Infections in Pigs: The Role of Virulence Factors in Pathogenesis and Protection." Vet ... "Host-Pathogen Interplay at Primary Infection Sites in Pigs Challenged with Actinobacillus Pleuropneumoniae." BMC Vet Res, vol. ... Infection, however, can also be asymptomatic depending on the strain of the bacteria. Pigs who survive the infection also ...
All animals were subsequently exposed to the infection induced by Actinobacillus pleuropneumoniae (App). The immune response ... Infecções por Actinobacillus , Actinobacillus pleuropneumoniae , Doenças dos Suínos , Suínos , Animais , Administração Cutânea ... Infecções por Actinobacillus/prevenção & controle , Infecções por Actinobacillus/veterinária , Vacinas Bacterianas , Anticorpos ... The results indicate that the 2/7/9 LRC mutant has promise as a vaccine against EHV-1 infection non-natural hosts. ...
A mouse model of PCP was established by intranasal infections with Actinobacillus pleuropneumoniae (App). Histopathological ... 5 Protective effect of lithium chloride on pulmonary injury caused by Actinobacillus pleuropneumoniae via inhibition of GSK-3β- ... Vindevogel H, Meulemans G, Pastoret PP (1982) Reovirus infection in the pigeon. Ann Rech Vet Rinaires Ann Vet Res 13: 149. Yun ... Infection, genetics and evolution: journal of molecular epidemiology and evolutionary genetics in infectious diseases 31: 177- ...
These organisms cause a wide range of infections, of which IE is one of the most notable. In order to control and prevent ... Invasive infections of Aggregatibacter (Actinobacillus) actinomycetemcomitans. J Microbiol Immunol Infect. 2010;43(6):491-7. ... HACEK microorganisms cause disease such as periodontal infections, bacteremia, endocarditis, and polymicrobial wound infections ... is standard treatment for 4 weeks for normal valve infection and for 6 weeks for synthetic valve infection. Surgical procedures ...
Bone and Joint Infections, Urinary Tract Infections, Genital Infections, and Skin and Soft Tissue Infections; or into etiologic ... Twenty-four Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella (i.e., HACEK) organisms were recovered from ... Bone and Joint Infections, Urinary Tract Infections, Genital Infections, and Skin and Soft Tissue Infections; or into etiologic ... Bone and Joint Infections, Urinary Tract Infections, Genital Infections, and Skin and Soft Tissue Infections; or into etiologic ...
in gingivitis, Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontitis.. URI: http://imsear.searo. ... Microbial flora in orodental infections. Indian Journal of Medical Microbiology. 2003 Apr-Jun; 21(2): 111-4. ... Ninety seven percent of orodental infections were polymicrobial and three or more microbes were found in 84% cases of study ...
Other Infection by more than one organism 023.9 Unspecified 024 Glanders Infection by: Actinobacillus mallei Farcy Malleomyces ... infection Rat tapeworm (infection) 123.8 Other Diplogonoporus (grandis) infection Dipylidium (caninum) infection Dog tapeworm ( ... infection) Threadworm infection 127.5 Capillariasis Infection by Capillaria philippinensis Excludes: infection by Capillaria ... infection) Human T-cell lymphotropic virus-III (disease) (illness) (infection) HTLV-III (disease) (illness) (infection) HTLV- ...
Actinobacillus equuli infections. *Gram-negative pleomorphic infections: Actinobacillus seminis, Histophilus ovis and ... from spirochaetal granulomas affecting the udder as well as from lesions caused by infections with Actinobacillus lignieresii, ...
  • Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine. (mpg.de)
  • First evidence for the role of early cytokines in pneumonia in swine came from experimental infections with Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae. (nih.gov)
  • Actinobacillus pleuropneumoniae (APP) causes a form of porcine pleuropneumonia that leads to significant economic losses in the swine industry worldwide. (koreamed.org)
  • APP, Actinobacillus pleuropneumoniae. (koreamed.org)
  • Biofilm formation is prevalent among field isolates of Actinobacillus pleuropneumoniae. (semanticscholar.org)
  • Serological characterisation of Actinobacillus pleuropneumoniae isolated from pigs in 1993 to 1996. (semanticscholar.org)
  • The effect of two different combinations of vaccines against Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae in pigs' lung health and. (eaphm.org)
  • Mycoplasma hyopneumoniae (Mhyo) and Actinobacillus pleuropneumoniae (A.p) are very common in swine farms worldwide and cause severe respiratory diseases with great economic impact. (eaphm.org)
  • Actinobacillus pleuropneumoniae , formerly known as Haemophilis pleuropneumoniae , is a member of the Pasteurellaceae family. (mechpath.com)
  • Figure 1: Lungs infected with A. pleuropneumoniae after 21 days after initial infection. (mechpath.com)
  • Sensitive bacteria are mainly Pasteurella multocida , Pasteurella hemolytica , Actinobacillus pleuropneumoniae , Salmonella , E.coli , Streptococcus , Staphylococcus , etc. (jxfineway.com)
  • Were assessed the serological antibodies occurrency of Mycoplasma hyopneumoniae , Actinobacillus pleuropneumoniae and swine influenza virus (SIV), as well as the evaluation of pulmonary Mycoplasma-like lung lesions, pleuritis, histopathological lesions and diseases occurrence associated with risk factors, such as management, housing and productive indexes. (biomedcentral.com)
  • It is additionally indicated for treatment of acute outbreaks of respiratory disease in pigs caused by strains of Actinobacillus pleuropneumoniae and Pasteurella multocida susceptible to florfenicol. (powerhorsevet.com)
  • Effects of heparin-binding protein (CAP37/azurocidin) in a porcine model of Actinobacillus pleuropneumoniae-induced pneumonia. (shengsci.com)
  • It mainly cures for the respiratory disease that caused by mycoplasma, animal infective pleuropneumonia that caused by actinobacillus and pasteurella multocida and breast infection of lactational animals. (jiulonghxyy.com)
  • It is commonly used for the treatment of the cattle acute respiratory system infection (e.g. bronchopneumonia caused by Pasteurella ), bovine mastitis, pig actinobacillus pleuropneumonia, etc in veterinary clinical. (jxfineway.com)
  • For pigs: for the treatment and control of gastrointestinal, respi- ratory and urogenitaly infections produced by microorganisms susceptible to enrofloxacin: Gram Negative bacteria (Pseudomonas aeruginosa, Pasteurella spp, Salmonella spp, E.coli, Actinobacillus spp, Shigella, Klebsiella, Campylobacter etc) Gram positive bacteria (Erysipelothrix rhusiopatiae, some strains of Streptococcus and Staphylococcus spp. (eventwall.ro)
  • Pasteurella spp, Salmonella spp, E.coli, Actinobacillus spp, Campylobacter etc) Gram positive bacteria (some strains of Streptococcus and Staphylococcus spp. (eventwall.ro)
  • Bacteriological, histopathological and immunohistochemical tests on lung samples showed that 97.2% of pneumonia lesions were caused by M. hyopneumoniae and Pasteurella multocida co-infection, highlighting the importance of those pathogens interaction for swine respiratory disease [ 5 ]. (biomedcentral.com)
  • it indicated for preventive and therapeutic treatment of respiratory tract infections in cattle due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. (powerhorsevet.com)
  • Distribution of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis by subject age. (semanticscholar.org)
  • in gingivitis, Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontitis. (who.int)
  • This study investigated the occurrence of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in the root canals of cleft lip and palate patients. (bvsalud.org)
  • Slots J, Ting M. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in human periodontal disease: occurrence and treatment. (thejcdp.com)
  • Our study revealed that similar to the GI mucosae, oral CD4 + T cells were rapidly depleted, and as one of the first comprehensive analyses of the oral microflora in SIV infection, we also observed significant modulation among two genera, Porphyromonas and Actinobacillus, early after infection. (duke.edu)
  • Periodontal infections are usually mixed, most often involving anaerobes such as Treponema denticola and Porphyromonas gingivalis . (medihelp365.com)
  • Portanto, este estudo avaliou por meio da técnica de Reação em Cadeia da Polimerase a presença dos micro-organismos Actinobacillus actinomycetemcomitans e Porphyromonas gingivalis de canais radiculares em pacientes com fissuras lábio-palatais. (bvsalud.org)
  • Other bacteria that are frequently isolated from clinical specimens concomitantly with Actinomyces in human infection include Actinobacillus actinomycetemcomitans, Eikenella corrodens, and species of Fusobacterium, Bacteroides, Capnocytophaga, Staphylococcus, Streptococcus, and Enterococcus. (medscape.com)
  • Virtually all cases are mixed infections with other bacteria including Eikenella corrodens , Bacteroides spp, S. aureus , Streptococcus spp. (hopkinsguides.com)
  • Nearly always part of a mixed infection, especially with flora such as Actinobacillus actinomycetemcomitans, Eikenella corrodens , Bacteroides spp , S. aureus , Streptococcus spp . (hopkinsguides.com)
  • Haemophilus , Actinobacillus , Cardiobacterium , Eikenella , and Kingella species (HACEK organisms) are particularly common in neonates and immunocompromised children. (medscape.com)
  • Some cases of culture-negative endocarditis are caused by fastidious gram-negative organisms of the Haemophilus parainfluenzae, Actinobacillus, Actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, Kingella kingae ( HACEK ) group, which constitutes approximately 1-3% of cases of community-acquired endocarditis on native and prosthetic valves, and may have a relatively good prognosis. (medscape.com)
  • Vaccination of piglets against Mycoplasma hyopneumoniae (Mh) is an effective way to reduce lungs lesions induced by Mh infection, and. (eaphm.org)
  • Approximately 25%-40% of infections also involve gram-positive bacteria, with Streptococcus spp being the predominant isolate. (msdvetmanual.com)
  • The crude extract and SNPs exhibited varying antimicrobial activities against some selected pathogens including Streptococcus pyogenes ATCC 19615, Klebsiella pneumoniae ATCC 10031, Bacillus sp, Actinobacillus sp. (bvsalud.org)
  • Prevalence of cdtABC genes encoding cytolethal distending toxin among Haemophilus ducreyi and Actinobacillus actinomycetemcomitans strains. (microbiologyresearch.org)
  • Actinomycotic mastitis in pigs should be differentiated from spirochaetal granulomas affecting the udder as well as from lesions caused by infections with Actinobacillus lignieresii, Staphylococcus spp. (anipedia.org)
  • Thus, toxic shock syndromes resulting from streptococcal or Staphylococcus aureus infection are hyperinflammatory septic syndromes that closely resemble diseases characterized by endotoxemia. (msdvetmanual.com)
  • The most common microbial infection is staphylococcus. (medscape.com)
  • Current situation of Actinobacillus pleuropneumonia in Spain according to lung lesions scored at slaughterhouse using the Ceva Lung Program (CLP). (eaphm.org)
  • In Spain vaccination against Actinobacillus pleuropneumonia (Ap) is still at a relative low level, approximately 5% of the pigs, and antimicrobials (AMs) are often used to prevent or control bacterial diseases, but over the last years, pig producers are. (eaphm.org)
  • nov. and recognition of a novel genomospecies for equine strains of Actinobacillus lignieresii. (semanticscholar.org)
  • This review concentrates on in vivo studies of cytokine involvement in infectious respiratory diseases of swine, with an emphasis on viral infections. (nih.gov)
  • Most of her research has been focused on the study of bacterial and viral infections in swine, and she has participated in many competitively funded and contract-based research projects, and research papers. (grupoasis.com)
  • The authors have previously shown that the periodontal pathogen Aggregatibacter (formerly Actinobacillus ) actinomycetemcomitans Y4 contains an operon for a genotoxin known as the cytolethal distending toxin (Cdt). (microbiologyresearch.org)
  • As early as the 1980s, reports were published of the association of periodontal pathogens, such as Actinobacillus actinomycetemcomitans , with subacute endocarditis. (cdeworld.com)
  • RESUMEN: El objetivo de este estudio fue determinar el efecto del propóleo sobre la terapia periodontal no quirúrgica en pacientes con periodontitis crónica (PC) en la literatura reciente. (bvsalud.org)
  • Mahuli SA, Zorair AM, Jafer MA, Sultan A. Antibiotics for Periodontal Infections: Biological and Clinical Perspectives. (thejcdp.com)
  • The review is to highlight the use of antibiotics in periodontal infections and prevent indiscriminate use of antibiotics. (thejcdp.com)
  • Increasingly I think this can be explained simply by the pigs that are affected have their immune system destroyed so that they cannot fight any infection. (thepigsite.com)
  • Some vets are attempting serum treatment derived from the blood of pigs that have recovered from the infection. (thepigsite.com)
  • Pigs who survive the infection also become asymptomatic carriers. (mechpath.com)
  • However, field observation suggests that most infected pigs eventually become immune, then cease to shed virus by 60 days post-infection. (iastate.edu)
  • She graduated in veterinary medicine from the University of Zaragoza in 1984 and obtained her PhD in veterinary medicine from the Autonomous University of Barcelona (UAB) in 1992, for her work on the epidemiology of coronavirus infections in pigs. (grupoasis.com)
  • Serological methods are the most commonly used diagnostic tools to detect Toxoplasma gondii infections in pigs. (usda.gov)
  • and wound infections and acute metritis caused by strains of staphylococcal and streptococcal organisms sensitive to oxytetracycline. (questiontime.info)
  • Common gram-negative pathogens include E coli , Klebsiella spp, Enterobacter spp, Actinobacillus spp, Salmonella spp, and Pseudomonas spp. (msdvetmanual.com)
  • In further studies, we will use more specific strategies to dissect the role of cytokines during viral infections. (nih.gov)
  • Although foals can respond immunologically in utero to bacterial or viral infections, their ability to do so is less than that of adults. (msdvetmanual.com)
  • The disease is strongly linked to environmental dust, pollen, and in some cases to preceding bacterial and viral infections. (madbarn.com)
  • Actinomyces radicidentis, a recently described species, has been isolated with polymerase chain reaction from patients with endodontic infections. (medscape.com)
  • The microaerophile Actinobacillus actinomycetemcomitans causes a rare form known as localized Juvenile Periodontitis. (medihelp365.com)
  • Los resultados muestran que existen muy pocos reportes enfocados a estudios clínicos, sin embargo, según los datos analizados, el propóleo podría ser un buen adyuvante para el tratamiento de pacientes con periodontitis crónica en comparación con el tratamiento convencional (SRP). (bvsalud.org)
  • Other bacterial species that often are copathogens to Actinomyces species may aid spread of infection by inhibiting host defenses and reducing local oxygen tension. (medscape.com)
  • For poultry: for the treatment and control of gastrointestinal and respiratory infections produced by microorganisms susceptible to enrofloxacin: Gram Negative bacteria (Pseudomonas aeruginosa. (eventwall.ro)
  • In infections with Pseudomonas spp. (eventwall.ro)
  • Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. (antikoerper-online.de)
  • This is accompanied by a steady decline in antibody titers over a period of four to eight months after infection. (iastate.edu)
  • The rate of culture-negative endocarditis varies from 7% to 33% and is increased in community-acquired infections because of antibiotic treatment before diagnosis. (medscape.com)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • In some cases, infection is manifested as an epidemic of respiratory disease or reproductive failure but in other outbreaks, infection may spread slowly. (iastate.edu)
  • Infective endocarditis (IE) is caused by infection of the heart valve blood by fungi and bacteria (this bacteremia can cause septic symptoms) and their vegetative growth, which consists mainly of platelets, microorganisms and fibrins. (biomedcentral.com)
  • Endocarditis is other infections. (cdc.gov)
  • Endocarditis is a noncontagious chronic infection of gave a comprehensive account of the disease and outlined the valves or lining of the heart, mainly caused by the difficulties in its diagnosis (2). (cdc.gov)
  • Our center in Marseille, France, has become a referral center for patients with T. whipplei infections and blood culture-negative endocarditis ( 2 , 5 , 6 ). (cdc.gov)
  • The Infection Window Period is lengthened for this event to accommodate the extended diagnostic timeframe that is frequently required to reach a clinical determination of endocarditis. (cdc.gov)
  • Bacterial endocarditis is a microbial infection of the endothelial surface of the heart. (medscape.com)
  • Infective endocarditis is defined as community-acquired or health care-associated infection. (mhmedical.com)
  • The term NBTE is still in current use, but this term and subacute bacterial endocarditis are to be discouraged, as not all infections are caused by bacteria. (medscape.com)
  • Detection of cytolethal distending toxin activity and cdt genes in Actinobacillus actinomycetemcomitans isolates from geographically diverse populations. (microbiologyresearch.org)
  • Lymph nodes are enlarged, which is often the case with infection but there is depletion of the normal lymphoid cells, which produce antibodies to fight disease and replaced with macrophages in the nodes and Peyers patches in the intestine suggesting, the body is attacking its own immune system, or something inside it. (thepigsite.com)
  • Production of IgG1, IgG2a, IgA, and IgE antibodies against excreted/secreted proteins and soluble extract was detected after infection by G. intestinalis. (usda.gov)
  • Ninety seven percent of orodental infections were polymicrobial and three or more microbes were found in 84% cases of study group as compared to 28% in controls. (who.int)
  • With regard to dog bites, at least 64 species of bacteria are found in the canine mouth, and many resulting infections are polymicrobial. (medscape.com)
  • Infections usually polymicrobial and may include abscess formation. (hopkinsguides.com)
  • Use of quinolones2 in livestock has been identified as a particular area of concern because of the significance of this group of antimicrobials for the treatment of a broad range of infections in humans including gastrointestinal infections caused by zoonotic bacteria transmitted to humans via the food chain. (who.int)
  • This chronic infection is characterized by histologic indication of gastrointestinal involvement, determined by a positive periodic acid-Schiff (PAS) reaction in macrophages from a small bowel biopsy sample ( 2 ). (cdc.gov)
  • 2) It may lead to gastrointestinal tract flora disorder or double infection. (jxfineway.com)
  • IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection. (umontreal.ca)
  • Once the organism is established locally, it spreads to surrounding tissues in a progressive manner, leading to a chronic, indurated, suppurative infection often with draining sinuses and fibrosis. (medscape.com)
  • These consortiums can colonize a variety of surfaces, such as host tissues, dentures, and catheters, resulting in infections highly resistant to drugs, when compared with their planktonic counterparts. (mdpi.com)
  • 1 Other congenital abnormalities of the aortic valve, degenerative calcific aortic stenosis, aortic insufficiency secondary to connective tissue disorders, and rheumatic aortic valve disease, are also predisposing lesions for infection. (mhmedical.com)
  • HIV/SIV infections lead to massive loss of mucosal CD4 + T cells and breakdown of the epithelial mucosa resulting in severe microbial dysbiosis and chronic immune activation that ultimately drive disease progression. (duke.edu)
  • A number of carditis stems from the work of Fernel in the early 1500s, complications may be associated with the disease such as and yet this infection still presents physicians with major blood clots, stroke, heart rhythm problems, abscesses, and diagnostic and management dilemmas. (cdc.gov)
  • The disease had, in fact, bacteria, although fungi can also be associated with this been described by a French Renaissance physician, Jean infection (1). (cdc.gov)
  • More than 100 years after Osler's lectures, this serious increases with the following conditions: congenital heart infection can still remain a diagnostic and therapeutic disease, rheumatic fever, major dental treatment, open dilemma. (cdc.gov)
  • Detection of prepatent infection is essential to control this disease. (usda.gov)
  • dangerous and exotic agents that pose a high individual risk of aerosol-transmitted laboratory infections and life-threatening disease that is frequently fatal, for which there are no vaccines or treatments, or a related agent with unknown risk of transmission. (absa.org)
  • Sepsis and SIRS are two of the most common problems of equine neonates, while bacterial infection accounts for nearly one-third of all foal mortality. (msdvetmanual.com)
  • Background: The growing incidence of multidrug resistant (MDR) bacterial infections has become a public health crisis. (bvsalud.org)
  • Pulmonary infections usually arise after aspiration of oropharyngeal or GI secretions. (medscape.com)
  • A chest radiograph is helpful to exclude pulmonary conditions that may be responsible for or are associated with the cause of pericarditis (ie, cancer, infection, SLE, sarcoidosis, etc). (medscape.com)
  • Surgical debride- man wound infection involving Lonepinella -like organisms ment and washout revealed pus within the thenar muscle occurring after koala bites in Queensland, Australia. (cdc.gov)
  • These organisms cause a wide range of infections, of which IE is one of the most notable. (biomedcentral.com)
  • Organisms may be present in cervical smears, does not represent infection. (hopkinsguides.com)
  • In this study we evaluated the effects of oral probiotic supplementation (PBX), which can stimulate and augment inflammatory or anti-inflammatory pathways, on early SIV infection of rhesus macaques. (duke.edu)
  • Collectively, these data provide one of the most comprehensive evaluations of SIV-induced changes in oral microbiome and CD4 + T cell populations, and also suggest that oral PBX may have some anti-inflammatory properties in lentivirus infections. (duke.edu)
  • Sepsis is a clinical syndrome defined by the development of a systemic inflammatory response syndrome (SIRS) in response to proven or suspected infection. (msdvetmanual.com)
  • Microbes and their derivatives by producing antigens and other inflammatory factors may trigger infection and inflammatory responses. (shengsci.com)
  • It is caused by Tropheryma whipplei and encompasses asymptomatic carriage of the organism to a wide spectrum of clinical pathologic conditions, including acute and chronic infections ( 1 , 2 ). (cdc.gov)
  • A major concern in all bite wounds is subsequent infection caused by bacteria, and, more rarely, viruses. (medscape.com)
  • Slowly progressing infection, often with granulomatous features categorized according to the body site (orocervical, thoracic, abdominopelvic). (hopkinsguides.com)
  • IMSEAR at SEARO: Microbial flora in orodental infections. (who.int)
  • Infection, however, can also be asymptomatic depending on the strain of the bacteria. (mechpath.com)
  • This generally has a detrimental effect on the host and is attributed to many chronic infections which poses a therapeutic challenge. (hindawi.com)
  • In addition, classification that implicates the disease's temporal aspect, etiology, anatomic site of infection, and relevant pathogenic risk factors is essential in therapeutic and prognostic considerations. (medscape.com)
  • Thirteen M. osloensis genes were identified to be up-regulated post infection in D. reticulatum . (biomedcentral.com)
  • Compared to the in vitro expressed genes in the stationary phase, we found that genes of ubiquinone synthetase ( ubiS ) and acyl-coA synthetase ( acs ) were up-regulated in both D. reticulatum and stationary phase in vitro cultures, but the remaining 11 genes were exclusively expressed in D. reticulatum and are hence infection specific. (biomedcentral.com)
  • We conclude that 11 out of the 13 up-regulated M. osloensis genes are infection specific. (biomedcentral.com)
  • The early cytokines interferon-alpha (IFN-alpha), tumour necrosis factor-alpha (TNF-alpha), interleukin-1, -6 and -8 (IL-1, -6, -8) are produced during the most early stage of an infection. (nih.gov)