Metastatic eccrine porocarcinoma: response to docetaxel (Taxotere) chemotherapy. (1/8)
BACKGROUND: Eccrine porocarcinoma is an uncommon neoplasm of the intra-epidermal sweat gland duct. PATIENTS AND METHODS: A case of eccrine porocarcinoma in a female renal transplant patient aged 45 years is described with a review of pertinent literature. RESULTS: The primary tumour was highly pleomorphic. In places large and small cells merged and focally the former component infiltrated the epidermis in a manner akin to Paget's disease of the breast. The majority of the tumour was high grade; using the modified Bloom and Richardson grading system, usually applied to mammary ductal carcinomas, the tumour graded as 3. Metastatic disease developed nine months following primary surgical treatment. The metastatic eccrine porocarcinoma was resistant to epirubicin but responded to docetaxel chemotherapy. CONCLUSIONS: There are no data to support the use of adjuvant therapy in the management of eccrine porocarcinoma. The use of the modified Bloom and Richardson grading system may define cases at high risk of relapse in which adjuvant therapy might be considered. Metastatic eccrine porocarcinoma has proven resistant to many chemotherapeutic agents. We report the first use of docetaxel in the management of this disease. The treatment was well tolerated and resulted in marked symptomatic and radiological responses. Treatment with docetaxel should be considered in future cases of this rare tumour. (+info)Eccrine porocarcinoma (malignant eccrine poroma): a case report. (2/8)
Eccrine porocarcinoma is a rare malignancy of eccrine sweat gland usually presenting as a long-standing growth on the lower extremity. It is more common in females. It may arise in a pre-existing eccrine poroma. A case presenting as nodular swelling over the dorsum of left hand in a 56-year-old man is described. Cytologic and histologic examination along with flow cytometric analysis is presented. (+info)Eccrine porocarcinoma. (3/8)
We present an unusual case of eccrine porocarcinoma in that diagnosis was delayed for many years after the initial lesion appeared, resulting in relatively large tumor. (+info)Poromatosis: the occurrence of multiple eccrine poromas. (4/8)
Eccrine poromas are rare, benign adnexal tumors derived from the intraepidermal portion of sweat ducts. Historically they were thought to arise from eccrine ducts although today it is thought that they may also have an apocrine origin. They usually appear as solitary, slow-growing, skin-colored papules on acral surfaces. Here we present the unusual situation of a patient with multiple poromas only three of which are located near the distal extremities. (+info)Eccrine poroma: a clinical-dermoscopic study of seven cases. (5/8)
(+info)Poroma of the hip and buttock. (6/8)
Poroma is a benign adnexal skin tumor seen in middle aged individuals with no sex predilection. The acral sites are the most commonly affected regions. Hip or buttock as a location of origin has rarely been reported. We report two cases of poroma, one located on the hip of a 75-year-old man and the other on the buttock of a 60-year-old man. (+info)EWS-Oct-4B, an alternative EWS-Oct-4 fusion gene, is a potent oncogene linked to human epithelial tumours. (7/8)
(+info)Dermoscopy of eccrine acrospiroma masquerading as nodular malignant melanoma. (8/8)
Eccrine acrospiroma, better known as eccrine poroma, is a benign adnexal neoplasm of the skin. Its clinical aspect can masquerade as some other nodular and cystic lesions. The current dermoscopy literature offers very few case studies. Moreover, these very few examples present a totally different appearance pattern compared to the one we examined. Its homogeneous blue pattern suggested the better-known nodular malignant melanoma; in fact, this dermoscopic appearance was due to the Tyndall effect. (+info)
Eccrine acrospiroma | definition of eccrine acrospiroma by Medical dictionary
Acrospiroma
Summary Report | CureHunter
Hidradenoma - Wikipedia
Porocarcinoma: case report
A Case of Clear Cell Eccrine Porocarcinoma
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Identification and topology of variant sequences within individual repeat domains of the human epithelial tumor mucin MUC1. -...
Courtney R. Schadt, M.D. - School of Medicine University of Louisville
Symptoms Of Eccrine Poroma: Causes, Diagnosis And Treatment
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Poromatosis in pregnancy: a case of 8 eruptive poromas in the third trimester.
Dermatologica Sinica
Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis...
benign eccrine tumor of the skin 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Stranger in a Strange Land: November 2013
Hidradenoma
Eccrine acrospiroma Clear-cell hidradenoma or acrospiroma Nodular hidradenoma or acrospiroma Solid-cystic hidradenoma ... For example, acrospiroma and hidradenoma are synonymous, and sometimes the term acrospiroma is used to generally describe ... Gross pathology of a cystic nodular hidradenoma Dermal duct tumor Acrospiroma, solid type Acrospiroma, clear cell type ... "Acrospiroma: a case report and review". Cutis. 58 (5): 349-51. PMID 8934076. Obaidat NA, Alsaad KO, Ghazarian D (February 2007 ...
Dermal cylindroma
Spiradenoma Malignant acrospiroma James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical ...
International Classification of Diseases for Oncology
Eccrine acrospiroma Clear cell hidradenoma M8402/3 Nodular hidradenoma, malignant (C44._) Hidradenocarcinoma M8403/0 Eccrine ...
Syringoma
Acrospiroma List of cutaneous conditions List of cutaneous neoplasms associated with systemic syndromes James, William D.; ...
Hidrocystoma
Syringoma Acrospiroma Seborrheic keratosis List of cutaneous conditions List of cutaneous neoplasms associated with systemic ...
Hidradenocarcinoma
... (also known as malignant hidradenoma, malignant acrospiroma, clear cell eccrine carcinoma, or primary ...
List of skin conditions
Aberrant basal cell carcinoma Acanthoma fissuratum (granuloma fissuratum, spectacle frame acanthoma) Acrospiroma (clear cell ... Malignant acrospiroma (spiradenocarcinoma) Malignant mixed tumor (malignant chondroid syringoma) Malignant trichilemmal cyst ...
List of MeSH codes (C04)
... acrospiroma, eccrine MeSH C04.557.470.035.175.375 - hidrocystoma MeSH C04.557.470.035.175.800 - syringoma MeSH C04.557.470.035. ... acrospiroma, eccrine MeSH C04.557.470.550.175.375 - hidrocystoma MeSH C04.557.470.550.175.800 - syringoma MeSH C04.557.470.550. ...
Spiradenoma
Malignant acrospiroma List of cutaneous conditions Dermal cylindroma Trichoepithelioma CYLD cutaneous syndrome List of ...
Poroma
This part of the sweat gland duct is termed the acrosyringium and had led to grouping poromas in the acrospiroma class of skin ...
List of diseases (A)
... dysplasia Acrophobia Acropigmentation of Dohi Acrorenal syndrome recessive Acrorenoocular syndrome Acrospiroma ACTH deficiency ...
Sweat gland
... tumors include: Acrospiroma Aggressive digital papillary adenocarcinoma Apocrine gland carcinoma Ceruminoma ...
Acrospiroma
... also termed clear cell acrospiroma), nodular hidradenoma (also termed nodular acrospiroma, clear cell myoepithelioma, and ... Media related to Acrospiroma at Wikimedia Commons v t e (Articles with short description, Short description matches Wikidata, ... The acrosporma group of tumors consists of: 1) the hidradenomas, including their eccrine acrospiroma, clear cell hidradenoma ( ... Helwig EB (October 1984). "Eccrine acrospiroma". Journal of Cutaneous Pathology. 11 (5): 415-20. doi:10.1111/j.1600-0560.1984. ...
Malignant acrospiroma
A malignant acrospiroma is a sweat gland carcinoma of the hand, which may recur locally in 50% of patients after excision, with ... Acrospiroma Syringoma Hidrocystoma List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007 ... ISBN 978-1-4160-2999-1. Wilson KM, Jubert AV, Joseph JI (May 1989). "Sweat gland carcinoma of the hand (malignant acrospiroma ...
Acrospiroma - Wikipedia
... also termed clear cell acrospiroma), nodular hidradenoma (also termed nodular acrospiroma, clear cell myoepithelioma, and ... Media related to Acrospiroma at Wikimedia Commons v t e (Articles with short description, Short description matches Wikidata, ... The acrosporma group of tumors consists of: 1) the hidradenomas, including their eccrine acrospiroma, clear cell hidradenoma ( ... Helwig EB (October 1984). "Eccrine acrospiroma". Journal of Cutaneous Pathology. 11 (5): 415-20. doi:10.1111/j.1600-0560.1984. ...
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Sonographic characteristics of apocrine nodular Hidradenoma of the skin<...
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A varied presentation of dermal adnexal tumours: An institutional study Sinha S, Das S, Raju K - Adv Hum Biol
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Sebaceous carcinoma - Wikipedia
SGc arises from the adnexal epithelium of sebaceous glands, most commonly the Meibomian glands or glands of Zeis.[9][6] On histology, there are irregular lobules of different sizes with undifferentiated cells and distinct sebaceous cells with a foamy cytoplasm.[9] The pathogenesis of SGc remains poorly understood.[5] The majority of SGc are solitary and sporadic and believed to be associated with such factors as ultraviolet exposure, radiotherapy, and immunosuppression.[10] Other SGc including those occurring outside of the head and neck region and the presentation of multiple at a time are believed to be associated with genetic defects including defects in mismatch repair genes, Muir-Torre syndrome (MTS), and familial retinoblastoma.[11][10][9] The observation of extraocular SGc arising from Bowen disease or actinic keratosis and the predisposition of SGc to arise in sun-exposed areas suggest a role for ultraviolet exposure or intraepidermal neoplasia in the pathogenesis of some SGc in ...
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A varied presentation of dermal adnexal tumours: An institutional study Sinha S, Das S, Raju K - Adv Hum Biol
Journal of Cutaneous and Aesthetic Surgery (JCAS): Table of Contents
Giant eccrine acrospiroma of the scalp. p. 238. Richa Todi, Chiranth Gowda, Kantilatha Pai, Gabriel Rodrigues. DOI:10.4103/JCAS ... Eccrine acrospiroma is a benign skin tumor that arises from the ducts of sweat glands, presents as small solid or cystic ... with a large pedunculated tumor of the scalp that was excised and histopathologically proven to be a giant eccrine acrospiroma ...
desmoplastic trichoepithelioma
Clear Cell Hidradenoma2
- Several cases have been published under various names, called MNH, clear cell hidradenocarcinoma, malignant clear cell hidradenoma, malignant clear cell myoepithelioma, and malignant acrospiroma. (handmicro.org)
- Acrospiroma - An acrospiroma (also known as a Clear cell hidradenoma, Dermal duct tumor, Hidroacanthoma simplex, Nodular hidradenoma, and Poroma [1]:665) is a tumor of the distal portion of a sweat gland. (en-academic.com)
Eccrine acrospiroma2
- 19. Dermoscopy of eccrine acrospiroma masquerading as nodular malignant melanoma. (nih.gov)
- Nodular hidradenoma , also known as eccrine acrospiroma or clear cell hidradenoma, is a dermal adnexal tumor that most commonly appears in the head and neck area or the extremities. (medscape.com)