Mercury poisoning: a rare but treatable cause of failure to thrive and developmental regression in an infant. (1/3)

An infant presented with failure to thrive and developmental regression. Physical examination revealed an irritable child with swollen, erythematous extremities, and elevated blood pressure. Extensive investigations, including a metabolic work-up and neuroimaging, were unrevealing. Exposure to self-purchased medication was initially denied. The physical signs were suggestive of acrodynia. Mercury poisoning was ultimately established by measuring paired blood and urine mercury levels. On further enquiry, it was revealed that the child had been given a Chinese medicinal product for 4 months. He responded well to a chelating agent. Acrodynia is a childhood disease considered to be of historical interest only, but making a diagnosis of mercury poisoning is rewarding because the response to treatment is good. This case highlights the common misconception that alternative medicines are safe and benign.  (+info)

Ancestry of pink disease (infantile acrodynia) identified as a risk factor for autism spectrum disorders. (2/3)

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Mercury as a health hazard. (3/3)

Pink disease has virtually disappeared since teething powders were withdrawn. We describe a case in a boy who was exposed to metallic mercury vapour. We discuss the potential health hazard of spilled elemental mercury in the house and the difficulties of removing it from the environment.  (+info)

Acrodynia is characterized by pink discoloration of the hands and feet, irritability, photophobia (sensitivity to light) and polyneuritis (inflamed nerves). It is caused by chronic exposure to mercury. The most common form of exposure in young children is ingesting mercury from a broken thermometer. The signs and symptoms of mercury toxicity may not appear until weeks or months after exposure has occurred. ...
A condition seen primarily in childhood, most often resulting from chronic exposure to mercury compounds which may result in encephalopathy and polyneuropathy.
INTRODUCTION. The detection of heavy metals in polluted environments is an ever-growing concern and is the subject of ongoing research in various research groups. Of the toxic heavy metals, mercury is one of the highly toxic, leading to diseases such as acrodynia (pinks disease), Hunter-Russell syndrome and Minamata disease (Fujiki and Tajima, 1992; He et al., 2009; Kudo et al., 1988). Health problems associated with mercury are made worse due to its accumulative and persistent nature in the environment and in living organisms. Mercury is released into water by industrial processes such as coal burning and natural causes like volcanic eruptions (Yari and Papi, 2009). South Africa has been reported as the second highest emitter (50 t-year-1) of Hg in the world, after China (Pacyna et al., 2006), even though later estimates dispute this high emission rate and place emissions in the range of 2.6-17.6 t-year-1 (Dabrowski et al., 2008). South Africa is the third-largest coal producer in the world, ...
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Looking for Pink's disease? Find out information about Pink's disease. tissue damage resulting from exposure to more than trace amounts of the element mercury mercury or quicksilver , metallic chemical element; symbol Hg ; at.... Explanation of Pink's disease
Dr. Phillips has often suggested that I be a stay at home Mom with Jenelle. We talked about this and I asked him directly if he was keeping something from us. He said he wasnt keeping anything from us, but felt that some kids do better with the one on one attention. We then talked about Jenelles developmental regression. He is very worried about this, and feels that she is going in the wrong direction. Jenelles PT has noted that she is weak on her right side, and Ive noticed that she is no longer rolling from tummy to back, something she used to do with ease. This could be because of the grand mals, or because Jenelle has an undiagnosed degenerative neurological condition. The later of course is the worst case scenario, but it does mean that if her condition is degenerative, she will regress until she dies. He said we werent there yet, but he is concerned because she is regressing, and since we dont have a diagnosis, this (the degenerative neurological condition) is not something we can ...
MalaCards based summary : Salt and Pepper Syndrome, also known as salt-and-pepper syndrome, is related to salt and pepper developmental regression syndrome and cohen syndrome. An important gene associated with Salt and Pepper Syndrome is B3GNT5 (UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5), and among its related pathways/superpathways are Metabolism and Synthesis of substrates in N-glycan biosythesis. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2) ...
Retts syndrome is a severe neurological disorder occurring mostly in girls. It is a type of autism spectrum disorder. It is a very serious disorder which leads to a developmental regression. The treatment for Retts syndrome lies in different therapies. Read on to know more.
Self-referral on The idea of one or more of the indicators of gastrointestinal troubles, developmental regression and an Affiliation with environmental publicity... Q: I asked you why you didnt help it become very clear, as We now have found with the letters that we checked out yesterday, that, at the least during the vast majority of cases, these small children came to begin with simply because their dad and mom believed that MMR experienced prompted that problem. You promptly to go a line in which you mention self-referral, but that particular reference would not incorporate the incredibly place that I am asking about, therefore you say is implicit, specifically the association with MMR. So how exactly does any reader, irrespective of whether a scientist, health practitioner or or else, read that into Whatever you say there? A: The patients, kids, are self-referred centered on dig this their signs or symptoms as well as their background. Which contains the 3 crucial things of the ...
Self-referral on The premise of a number hop over to here of on the indications of gastrointestinal troubles, developmental regression and an association with environmental exposure... Q: I questioned you why you did not enable it to be obvious, as Weve got found from your letters that we looked at yesterday, that, at the least in the vast majority of cases, these young children came in the first place mainly because their mom and dad imagined that MMR had prompted that situation. You right away to go a line where you take a look at self-referral, but that particular reference would not include things like the extremely point that im inquiring about, so you say is implicit, namely the association with MMR. How does any reader, no matter whether a scientist, physician or normally, browse that into Anything you say there? A: The sufferers, youngsters, are self-referred dependent on their own signs and symptoms as well as their historical past. That contains the three vital features of the ...
After recovering from a sickness that would bring him to the edge of despair, Eric Gladen began researching the science behind what had made him so sick. His research led him straight into one of the biggest medical debates of all time, the question of whether or not childhood vaccines are causing Autism. He would end up quitting his career, moving into an RV, and traveling the country interviewing experts and piecing together thousands of studies and leaked documents. But Eric wasn t focused on the vaccines themselves, he was focused on something that belongs nowhere near vaccines- mercury.. From the Mad Hatter Syndrome in the late 1800 s, to Pink Disease in the first half of the 20th century, humans have learned time and again of the debilitating neurological and physical damage that mercury can cause. Then why and how did it end up in our childhood vaccines? Trace Amounts explores the origin of the use of mercury in the vaccines and exposes the continued greed based decision to keep mercury ...
Apply for Certified Medical Assistant (CMA) - Cardiovascular Electrophysiology job with Wellstar in Georgia-Marietta. Browse and apply for Wellstar Medical Group jobs at Wellstar Health System
Rett syndrome is a neurodevelopmental disorder caused by a mutation in the X-linked MECP2 gene. Individuals with Rett syndrome typically develop normally until around 18 months of age before undergoing a developmental regression, and the disorder can lead to cognitive, motor, sensory, and autonomic dysfunction. Understanding the mechanism of developmental regression represents a unique challenge when viewed through a neuroscience lens. Are circuits that were previously established erased, and are new ones built to supplant old ones? One way to examine circuit-level changes is with the use of electroencephalography (EEG). Previous studies of the EEG in individuals with Rett syndrome have focused on morphological characteristics, but few have explored spectral power, including power as an index of brain function or disease severity. This study sought to determine if EEG power differs in girls with Rett syndrome and typically developing girls and among girls with Rett syndrome based on various clinical
Expressive dysphasia and mutism are common clinical features in children and adults with N-methyl-d-aspartate receptor antibodies (NMDAR-Ab) encephalitis, and are likely to result from NMDAR hypofunction. A prodromal loss of social and communication skills can typify that of an autistic regression, particularly when presenting under the age of 3 years. Here we describe two toddlers who presented with developmental regression, particularly of their social communication skills, mimicking an autistic regression, who were found to have NMDAR-Ab in the serum and cerebrospinal fluid. Although both patients had some other neurological features, they were subtle, which resulted in delayed diagnosis of NMDAR-Ab encephalitis. Importantly, immunotherapy was beneficial in both patients, with significant improvement of their language skills and behaviour.
Low (Sharma and Mohanan, 1980; Chacko et al., 2002). Pink disease caused by Corticium salmonicolor; stem canker caused by Cytospora eucalypticola and C. eucalypti (Sharma et al., 1990) and Cryphonectria canker disease. Outbreaks are localised up to 30% of the trees in a stand. Infection usually occurs on the main stem 1-1.5 m above ground and occasionally near ground level (Sharma et al., 1985). Web blight is caused by Rhizoctonia solani, damping-off by Pythium myriotylum and P. deliense, seedling blight by Cylindrocladium camelliae, leaf and shoot blights by C. clavatum and seedling wilt and root rot by Sclerotium rolfsii (Sharma et al., 1984; Mohanan and Sharma, 1985 ...
Background: Research indicates that some children with autism spectrum disorder (ASD) experience a developmental regression. Aims: The study examined the percentage of children with autism, pervasive developmental disorder (PDD), ASD, and Asperger syndrome (AS) who were considered to be delayed (D), regressed (R), or delayed and later regressed (DR) and examined any relationship with autism severity, time of onset, factors associated with onset, gastrointestinal (GI) symptoms, race, age, and gender. Materials and Methods: The study reviewed developmental and medical information based on parental reports of 135 children with a diagnosis of autism, PDD, ASD, or AS. Results: The number of children in the D group was 53 (39.2%) with 19 (14.1%) in the DR group and 63 (46.7%) in the R group. Thus, 82 children (60.7%) were reported to have R. In regard to onset of symptoms, there was a significant difference between the D and R groups as well as between the DR and R groups. The analyses showed that ...
The symptoms of Leigh syndrome are classically described as beginning in infancy and leading to death within a span of several years;[1] however, as more cases are recognized, it is apparent that symptoms can emerge at any age-including adolescence or adulthood-and patients can survive for many years following diagnosis.[5] Symptoms are often first seen after a triggering event that taxes the bodys energy production, such as an infection or surgery. The general course of Leigh syndrome is one of episodic developmental regression during times of metabolic stress. Some patients have long periods without disease progression while others develop progressive decline.[6] Infants with the syndrome have symptoms that include diarrhea, vomiting, and dysphagia (trouble swallowing or sucking), leading to a failure to thrive.[1] Children with early Leigh disease also may appear irritable and cry much more than usual. Seizures are often seen. Excess lactate may be seen in the urine, cerebrospinal fluid, and ...
Autism spectrum disorder (ASD) is a neurological disorder in which a significant number of the children experience a developmental regression characterized by a loss of previously acquired skills and abilities. Typically reported are losses of verbal, nonverbal, and social abilities. Several recent studies suggest that children diagnosed with an ASD have abnormal sulfation chemistry, limited thiol availability, and decreased glutathione (GSH) reserve capacity, resulting in a compromised oxidation/reduction (redox) and detoxification capacity. Research indicates that the availability of thiols, particularly GSH, can influence the effects of thimerosal (TM) and other mercury (Hg) compounds. TM is an organomercurial compound (49.55% Hg by weight) that has been, and continues to be, used as a preservative in many childhood vaccines, particularly in developing countries. Thiol-modulating mechanisms affecting the cytotoxicity of TM have been identified. Importantly, the emergence of ASD symptoms post-6 months
Ataxia is a common clinical feature in inherited metabolic disorders. There are more than 150 inherited metabolic disorders in patients presenting with ataxia in addition to global developmental delay, encephalopathy episodes, a history of developmental regression, coarse facial features, seizures, …
Monies et al. (2017) reported the findings of 1000 diagnostic panels and exomes carried out at a next generation sequencing lab in Saudi Arabia. One patient, a 1-year-old female from a consanguineous family, presented with microcephaly, fine/gross motor delay, speech delay, learning disability, developmental regression, periventricular leukomalacia, prematurity, oligohydramnios, nystagmus and recurrent fever. Whole exome sequencing helped identify a homozygous mutation (c.70G,T, p.E24X) in exon 3 of the patients SIRT2 gene. This gene mutation was considered a candidate for pathogenicity as it was a novel variant located within the autozygome and was predicted to be deleterious; and the gene had been implicated in myelination. The authors noted the need for independent confirmation of this association. ...
Monies et al. (2017) reported the findings of 1000 diagnostic panels and exomes carried out at a next generation sequencing lab in Saudi Arabia. One patient, a 1-year-old female from a consanguineous family, presented with microcephaly, fine/gross motor delay, speech delay, learning disability, developmental regression, periventricular leukomalacia, prematurity, oligohydramnios, nystagmus and recurrent fever. Whole exome sequencing helped identify a homozygous mutation (c.70G,T, p.E24X) in exon 3 of the patients SIRT2 gene. This gene mutation was considered a candidate for pathogenicity as it was a novel variant located within the autozygome and was predicted to be deleterious; and the gene had been implicated in myelination. The authors noted the need for independent confirmation of this association. ...
At least 30 mutations in the MFSD8 gene have been found to cause CLN7 disease. This condition typically starts in early childhood with the loss of previously acquired skills (developmental regression), recurrent seizures (epilepsy), muscle twitches (myoclonus), difficulty coordinating movements (ataxia), speech impairment, and vision loss. Mental functioning and motor skills (such as sitting and walking) decline with age. Individuals with CLN7 disease typically do not survive past their teens.. MFSD8 gene mutations that cause CLN7 disease likely lead to the production of a protein with altered structure or function. One MFSD8 gene mutation is responsible for almost all cases of CLN7 disease in the Roma population of the Czech Republic. This mutation replaces the protein building block (amino acid) threonine with the amino acid lysine at position 294 in the MFSD8 protein (written as T294K). A variety of other mutations cause the condition in other populations.. It is unclear how an altered MFSD8 ...
In the 1940s, thimerosal was used in teething powders for infants and resulted in fatal outbreaks of Pinks Disease (severe mercury poisoning) before being removed in the 50s. Since many children today receive vaccines with trace amounts of thimerosal, in addition to vaccines containing adjuvant aluminum compounds, an important 1972 study published in the British Medical Journal noted that mercury increases aluminums oxidation and produces abnormal heat. In recent years, there is growing evidence of mitochondrial oxidation and cellular damage that may be due to this interaction between mercury and aluminum in vaccines. With a child now receiving 31 and more vaccinations during its first 18 months of life, it would seem that this barbaric practice would have been fully investigated by our health officials to account for the epidemic rise in neurological and behavioral disorders, adult diabetes and asthmatic conditions in American children. Instead, our health officials continue to pump out ...
Epileptic spasms, also known as infantile spasms, juvenile spasms, or West syndrome is an uncommon-to-rare epileptic disorder in infants, children and adults. It is named after the English physician, William James West (1793-1848), who first described it in an article published in The Lancet in 1841. The original case actually described his own son, James Edwin West (1840-1860). Other names for it are generalized flexion epilepsy, infantile epileptic encephalopathy, infantile myoclonic encephalopathy, jackknife convulsions, massive myoclonia and Salaam spasms. The term infantile spasms can be used to describe the specific seizure manifestation in the syndrome, but is also used as a synonym for the syndrome itself. West syndrome in modern usage is the triad of infantile spasms, a pathognomonic EEG pattern (called hypsarrhythmia), and developmental regression - although the international definition requires only two out of these three elements. The syndrome is age-related, generally ...
To the Editor: We report on another child with subacute sclerosing panencephalitis (SSPE), expanding the case series reported by Kija et al. to six affected children from the Western Cape region of South Africa (SA) diagnosed in the past 18 months. The child presented to Red Cross War Memorial Children's Hospital, Cape Town, at 6 years and 3 months of age. She had recently returned to SA after living for several years in Zimbabwe. Her caregivers in SA had not seen her regularly, but understood that her previous health and development had been normal. She was admitted with a reported 1-day history of sudden onset weakness and abnormal movements. She had no known history of toxin exposure or prodromal symptoms prior to her presentation. She had neuro developmental regression and demonstrated emotional lability with incoherent speech and disorientation. She was not independently mobile.Her tone and power were normal and symmetrical with brisk deep tendon reflexes. Her abnormal movements were noted to
Acetobacter aceti has yet to be reported as a pathogenic microbe to humans or animals. Acetobacter aceti does not produce any toxins, enzymes, or any viruses that harm any human or animal. Since Acetobacter aceti is ubiquitous in nature and there is contact of this bacterium on all animals on a frequent basis. Acetobacter aceti is not a portion of normal flora of bacteria on human skin. The only potential pathology it could present is if presented in mass quantities, an allergic or immune response could occur. Acetobacter aceti does produce alcohols, meaning if consumed in large quantities, these alcohols could affect the central nervous system, causing intoxication via alcohol, a byproduct of Acetobacter aceti, although alcoholism or intoxication is not due to the bacterium. Acetobacter aceti is known to cause rotting and browning discoloration in fruits such as apples, pears, and citrus products. Acetobacter aceti is known for causing pink disease in pineapple, which is the turning of the ...
This case of acrodynia was traced to exposure of mercury from a carton of 8-foot fluorescent light bulbs that had broken in a ... Acrodynia is difficult to diagnose, "it is most often postulated that the etiology of this syndrome is an idiosyncratic ... Infantile acrodynia (also known as "calomel disease", "erythredemic polyneuropathy", and "pink disease") is a type of mercury ... Acrodynia resulted primarily from calomel in teething powders and decreased greatly after calomel was excluded from most ...
Babies given calomel for teething often suffered from acrodynia. It became popular in the late 18th century to give calomel in ...
Infantile acrodynia (childhood mercury poisoning) is characterized by excessive perspiration. A clinician should immediately ... consider acrodynia in an afebrile child who is sweating profusely. Some people can develop a sweat allergy. The allergy is not ...
Infantile acrodynia[uredi , uredi kodo]. Bolezen je znana tudi pod imenom kalomelna bolezen, erythredemična polinevropatija in ... Acrodynia je bila razmeroma pogosta med otroci v prvi polovici 20. stoletja. Na začetku vzrok za epidemijo acrodynije pri ... Tunnessen WW Jr, McMahon KJ, Baser M (1987). "Acrodynia: exposure to mercury from fluorescent light bulbs". Pediatrics 79 (5): ... Iz leta 1987 izhaja poročilo o 23-mesečnem otroku, ki se je zastrupil z živim srebrom (infantile acrodynia) in utrpel posledice ...
Exposure to mercury, including infantile acrodynia. *Excessive dietary magnesium, as with supplementation.[citation needed] ...
Mercury poisoning can result in several diseases, including acrodynia (pink disease), Hunter-Russell syndrome, and Minamata ...
Warkany and Hubbard (1953) noted in their seminal paper establishing mercury as the cause of infantile acrodynia that "... in ... in addition to the sharp decline in infantile acrodynia cases after the late 1950s following the removal of many sources of ...
It was removed from most powders in 1954 when it was shown to cause "pink disease" (acrodynia), a form of mercury poisoning. ...
... dermatitis acrodynia). He named this substance vitamin B6. In 1938, Richard Kuhn was awarded the Nobel Prize in Chemistry for ...
Exposure to mercury, including infantile acrodynia. *Decreased magnesium.[9]. *Excessive dietary zinc, as with supplementation ...
Acrodynia (calomel disease, erythredemic polyneuropathy, pink disease) Acute generalized exanthematous pustulosis (pustular ...
Acrodynia Atypical facial pain Autism Cerebral palsy Disturbed sleep patterns and other sleep disorders, such as obstructive ...
... now acrodynia or erythrœdema. Swift was born in Ely, Cambridgeshire, the son of John Swift, of "Woodhouse", Ely. He was ...
... kidney disease Neurobehavioral impairment Minamata disease Cerebellar ataxia Kidney and autoimmune dysfunction Acrodynia ...
... can refer to: Acrodynia, a condition caused by mercury poisoning, also known as pink disease Phanerochaete ...
In a 2006 NBC News interview, Adams noted that acrodynia, a condition that afflicted children roughly a hundred years ago, was ... found to be caused by mercury-containing teething powders, and that "symptoms of acrodynia were pretty similar to symptoms of ...
... a camouflage colour applied to British ships during World War Two Acrodynia, also known as "Pink's Disease" Pink, a fictional ...
... acrodynia MeSH C10.886.425.175 - sleep deprivation MeSH C10.886.425.200 - sleep disorders, circadian rhythm MeSH C10.886. ... acrodynia MeSH C10.668.829.050 - amyloid neuropathies MeSH C10.668.829.050.050 - amyloid neuropathies, familial MeSH C10.668. ...
Infections Encephalitis Guillain-Barré syndrome Infant botulism Meningitis Poliomyelitis Sepsis Toxins Infantile acrodynia ( ...
... infantile acrodynia). Classically, five days of fever plus four of five diagnostic criteria must be met to establish the ...
... disease Fibromyalgia Congestive heart failure Anxiety Obesity Menopausal state Night sweats Compensatory Infantile acrodynia ...
... acrodynia MeSH C21.613.680.262 - ergotism MeSH C21.613.680.551 - mushroom poisoning MeSH C21.613.705.100 - akathisia, drug- ...
The word acrodynia is derived from the Greek word ακρος, which means end or extremity, and οδυνη, which means pain. As such, it ... Acrodynia is a condition of pain and dusky pink discoloration in the hands and feet most often seen in children chronically ... However, acrodynia is a disease rather than a symptom. The condition is known by various other names including pink disease, ... "Acrodynia: a case report of two siblings". Arch Dis Child. 86 (6): 453. doi:10.1136/adc.86.6.453. PMC 1762992. PMID 12023189. ...
... dermatitis acrodynia). He named this substance vitamin B6.[46][47] In 1938, Samuel Lepkovsky isolated vitamin B6 from rice bran ...
Hy neamde de faktor "rat acrodynia factor" of adermine. Yn 1938 slaggen fiif ferskillende groepen wittenskippers, wêrûnder ... dermititis acrodynia) tefoaren komme koe. De Hongaarske mikrobiolooch en biogemikus Paul György beskreau yn 1934 as earste ...
Research has identified health-behavioral and biological factors that are related to increased risk for CVD. These risk factors include smoking, obesity, low density lipoprotein (the "bad" cholesterol), lack of exercise, and blood pressure. Psychosocial working conditions are also risk factors for CVD.[1] In a case-control study involving two large U.S. data sets, Murphy (1991) found that hazardous work situations, jobs that required vigilance and responsibility for others, and work that required attention to devices were related to increased risk for cardiovascular disability.[66] These included jobs in transportation (e.g., air traffic controllers, airline pilots, bus drivers, locomotive engineers, truck drivers), preschool teachers, and craftsmen. Among 30 studies involving men[67] and women,[68] most have found an association between workplace stressors and CVD. Fredikson, Sundin, and Frankenhaeuser (1985) found that reactions to psychological stressors include increased activity in the ...
For medical devices, risk management is a process for identifying, evaluating and mitigating risks associated with harm to people and damage to property or the environment. Risk management is an integral part of medical device design and development, production processes and evaluation of field experience, and is applicable to all types of medical devices. The evidence of its application is required by most regulatory bodies such as the US FDA. The management of risks for medical devices is described by the International Organization for Standardization (ISO) in ISO 14971:2007, Medical Devices-The application of risk management to medical devices, a product safety standard. The standard provides a process framework and associated requirements for management responsibilities, risk analysis and evaluation, risk controls and lifecycle risk management. The European version of the risk management standard was updated in 2009 and again in 2012 to refer to the Medical Devices Directive (MDD) and Active ...
Diagnosis is primarily anecdotal, that is, it depends upon a good occupational history. Diagnosis of metal fume fever can be easily missed because the complaints are non-specific, resemble a number of other common illnesses, and presentation occurs typically 2-10 hours after the exposure.[11] When respiratory symptoms are prominent, metal fume fever may be confused with acute bronchitis or pneumonia. The diagnosis is based primarily upon a history of exposure to metal oxide fumes. Cain and Fletcher (2010) report a case of metal fume fever that was diagnosed only by taking a full occupational history and by close collaboration between primary and secondary health care personnel.[12] Physical symptoms vary among persons exposed, depending largely upon the stage in the course of the syndrome during which examination occurs. Patients may present with wheezing or crackles in the lungs. They typically have an increased white blood cell count, and urine, blood plasma and skin zinc levels may ...
... is a standards organisation established in 1922 and is recognised through a Memorandum of Understanding with the Australian government as the peak non-government standards development body in Australia. It is a company limited by guarantee, with 73 members representing groups interested in the development and application of technical standards and related products and services. The Memorandum of Understanding between the Commonwealth and Standards Australia recognises Standards Australia as Australia's representative on the International Organization for Standardization (ISO), the International Electrotechnical Commission (IEC) and the Pacific Area Standards Congress (PASC).[1] Standards Australia develops internationally aligned Australian standards (AS) and participates in standards-related activities that deliver benefit to the nation. Standards Australia and Standards New Zealand work together to develop joint standards (AS/NZS). Standards Australia is also the Principal ...
The word acrodynia is derived from the Greek word ακρος, which means end or extremity, and οδυνη, which means pain. As such, it ... Acrodynia is a condition of pain and dusky pink discoloration in the hands and feet most often seen in children chronically ... However, acrodynia is a disease rather than a symptom. The condition is known by various other names including pink disease, ... "Acrodynia: a case report of two siblings". Arch Dis Child. 86 (6): 453. doi:10.1136/adc.86.6.453. PMC 1762992. PMID 12023189. ...
This case of acrodynia was traced to exposure of mercury from a carton of 8-foot fluorescent light bulbs that had broken in a ... Acrodynia is difficult to diagnose, "it is most often postulated that the etiology of this syndrome is an idiosyncratic ... Infantile acrodynia (also known as "calomel disease", "erythredemic polyneuropathy", and "pink disease") is a type of mercury ... Acrodynia resulted primarily from calomel in teething powders and decreased greatly after calomel was excluded from most ...
Mercury poisoning results in acute and chronic toxicity including acrodynia, as well as neurological and kidney damage. ...
Exposures to high levels of metallic mercury can lead to a rare condition in children called acrodynia, characterized by ...
acrodynia (1) * adult onset (1) * age of autism (2) * allman (1) * amalgam (2) ...
Close more info about Heavy Metal Dermatoses: Mercury(Mercury dermatosis: Hydrargyria, mercurialism, acrodynia, pink disease ... Close more info about Heavy Metal Dermatoses: Mercury(Mercury dermatosis: Hydrargyria, mercurialism, acrodynia, pink disease ... Heavy Metal Dermatoses: Mercury(Mercury dermatosis: Hydrargyria, mercurialism, acrodynia, pink disease, Mad Hatters disease ...
... rocking among infants with acrodynia (Warkany and Hubbard, 1953); and (g) unusual postures observed in both acrodynia and ... One adult acrodynia victim described himself as a boy as "shying away from people wanting to touch me" due to extreme touch ... Acrodynia sufferers describe excessive pain when bumping limbs, numbness, and poor circulation (Farnesworth, 1997). ... poor coordination and clumsiness among victims of acrodynia (Farnesworth, 1997); (f) ...
Infantile acrodynia (childhood mercury poisoning) is characterized by excessive perspiration. What does perspire mean? ... Infantile acrodynia (childhood mercury poisoning) is characterized by excessive perspiration. What does perspire mean? ... leukemias) can also cause diaphoresis.[16]. A clinician should immediately consider acrodynia in an afebrile child who is ... leukemias) can also cause diaphoresis.[16]. A clinician should immediately consider acrodynia in an afebrile child who is ...
Mercury poisoning can also result in several diseases including acrodynia, Hunter-Russell […] ...
It can also cause several diseases including acrodynia, Minamata disease, and Hunter-Russell syndrome. The problem is that ...
Acrodynia such as emotional instability, loss of appetite, general weakness, and skin changes, Cognitive/neurological ...
Acrodynia Asbestosis Asthma Barotrauma Berylliosis Dimitri Peters Byssinosis "brown lung" Chalicosis Chimney sweeps carcinoma ...
  • In 1934, a Hungarian physician, Paul György discovered a substance that was able to cure a skin disease in rats (dermititis acrodynia), this substance he named vitamin B 6 . (princeton.edu)
  • Joseph Goldberger hie yn 1926 by rotten ûntdutsen dat tafoeging fan in lytse hoemannichte bakkersgist oan it iten in pellagra-eftige hûdsykte (dermititis acrodynia) tefoaren komme koe. (wikipedia.org)
  • The names most commonly employed at present are erythredema-polyneuritis, erythredema, pink disease, Swift's disease, acrodynia and Feer's disease. (jamanetwork.com)
  • erythredema polyneuropathy acrodynia . (thefreedictionary.com)
  • Another prevailing, sometimes fatal, disease that affected children through the late 1940s was called acrodynia (or pink disease), meaning "pain in the hands and feet. (westonaprice.org)
  • In the early 1940s, acrodynia, or pink mottled or blotchy rash, mainly on trunk does your child may have residual headache and dizziness. (biointegrity.org)
  • Mercury poisoning (also known as mercurialism , hydrargyria , Hunter-Russell syndrome , or acrodynia when affecting children) is a disease caused by exposure to mercury or its toxic compounds. (bionity.com)
  • Acrodynia is characterized by pink discoloration of the hands and feet, irritability, photophobia (sensitivity to light) and polyneuritis (inflamed nerves). (wikidoc.org)
  • On December 1, the patient's 11-year-old sister was hospitalized with hypertension, mild acrodynia, irritability, and mild generalized muscle weakness. (cdc.gov)
  • It would be wise to learn from the lesson of acrodynia, and consider amalgam mercury among other possible factors in neurological and immunological diseases of unclear etiology. (nih.gov)
  • 1] Mercury poisoning can result in several diseases, including acrodynia (pink disease)[2], Hunter-Russell syndrome, and Minamata disease. (cityprofile.com)
  • From December 1, 1989, to April 4, 1990, the male patient's 24-hour urine mercury values declined from 1540 ug/L to 101 ug/L. Except for a persistent mild tremor, acrodynia and other neurologic symptoms resolved following two 21-day courses of DMSA therapy. (cdc.gov)
  • All patients showed symptoms of acrodynia. (aappublications.org)
  • Infantile acrodynia (childhood mercury poisoning) is characterized by excessive perspiration. (thefullwiki.org)
  • With Cheek he wrote a paper, `Pink Disease or Infantile Acrodynia: Its Nature, Prevention and Cure', for the Medical Journal of Australia (1950). (edu.au)
  • 6 , 9 - 15 Edathamil calcium disodium (EDTA) when given for therapy of acrodynia did not significantly increase mercury excretion. (nap.edu)
  • citation needed] However, mercury poisoning and acrodynia still exist today. (wikipedia.org)
  • mercury poisoning: …children, a disorder known as acrodynia, or "pink disease," is believed to be caused by an organic mercury compound, phenylmercuric propionate, which is incorporated into house paints to prevent the growth of mold. (britannica.com)
  • On November 22, 1989, a 15-year-old male who had been hospitalized in Columbus, Ohio, was diagnosed with acrodynia, a form of mercury poisoning. (cdc.gov)
  • Henningsson C, Hoffmann S, McGonigle L, Winter JS (1993) Acute mercury poisoning (acrodynia) mimicking pheochromocytoma in an adolescent. (springer.com)
  • Acrodynia in children is rare but is caused by mercury poisoning. (yeastinfectionadvisor.com)
  • Dr. Mary Agocs, a medical epidemiologist in the agency's center for environmental health and injury control, said officials first became concerned about the mercury content in paint after a Michigan boy was hospitalized for four months last year with acrodynia, a type of mercury poisoning. (edweek.org)
  • The use of thimerosal in teething powders for infants leads to a fatal out break of Acrodynia, or "Pink's Disease", a form of mercury poisoning. (blogspot.com)
  • Methylmercury exposure in children may result in acrodynia (pink disease) in which the skin becomes pink and peels. (wikipedia.org)
  • Acrodynia is a disease caused by exposure to poisonous levels of heavy metals, usually mercury. (wellnessbin.com)
  • Acrodynia is a condition of pain and dusky pink discoloration in the hands and feet most often seen in children chronically exposed to heavy metals, especially mercury. (wikipedia.org)
  • These two distinct features are responsible for the synonyms of "acrodynia" and "pink disease. (psychiatryadvisor.com)
  • As a resident medical officer in 1947-50 at Royal Adelaide and Adelaide Children's hospitals, Cheek encountered his first patient with pink disease (acrodynia). (edu.au)
  • When analysis of a 24-hour urine collection detected a mercury level of 840 ug/L (reference: less than 20 ug/L (1)), acrodynia was diagnosed. (cdc.gov)
  • Warkany J, Hubbard DM (1948) Mercury in the urine of children with acrodynia. (springer.com)
  • They found a striking parallel in acrodynia, a 1930's ailment that occurred in some children exposed to mercury in lotions and teething powders. (nytimes.com)
  • He is credited with discovering the cause - mercury in infants' teething powder and worm treatment − of acrodynia. (cincinnatichildrens.org)
  • However, acrodynia is a disease rather than a symptom. (wikipedia.org)
  • Warkany J (1966) Acrodynia - postmortem of a disease. (springer.com)
  • Some practice population were:8 patients with cardiac disease or acrodynia. (cadasb.org)
  • therefore, the veress needle, open laparoscopy, or direct branches of coronary heart disease or acrodynia. (yogachicago.com)
  • Surgical assistance should be avoided in pregnancy are similar to the combined action of thyroid disease or acrodynia. (bigsurlandtrust.org)
  • A physician should immediately consider acrodynia in an afebrile child who is sweating profusely. (thefullwiki.org)
  • Case of acrodynia in a child]. (exlibrisgroup.com)
  • The term acrodynia (ακρος an extremity, όδύνη pain) was coined about 1830 in France to meet the need of a word to designate a condition regarded as altogether new and hitherto undescribed under any other single designation. (ajtmh.org)
  • I write a weekly column for my local paper about climate change and I'm also someone with a condition called acrodynia, hyper-reactivity to mercury. (environmentalleader.com)
  • Later on, her condition would be called acrodynia , or painful tips, named so for the sufferer's aching hands and feet. (thestar.com)
  • Weston, 1 who is responsible for the term acrodynia, which is probably the most widely used at present, applied it to a group of cases reviewed by Bilderbach. (jamanetwork.com)
  • Fitamine B6 is de term dy't brûkt wurdt om in groep fan natuerlike pyridinederivaten en har fosfaatesters oan te tsjutten dy't yn it lichem yninoar omset wurde kinne. (wikipedia.org)
  • Alle trije foarmen fan fitamine B6 (pyridoksine, pyridoksal en pyridoksamine) wurde yn de tinne term maklik opnommen. (wikipedia.org)
  • In rare cases, thimerosal has caused systemic immune reactions including acrodynia. (diva-portal.org)
  • The mercury was found in a water-base house paint, and we believe this to be the first report of acrodynia from this source of mercury. (nap.edu)
  • The word acrodynia is derived from the Greek word ακρος, which means end or extremity, and οδυνη, which means pain. (wikipedia.org)
  • Acrodynia seems to be the result of a weak variant of a gene that governs mercury detoxification. (environmentalleader.com)
  • After both patients were diagnosed as having acrodynia with neuropsychiatric impairment, they were treated with oral 2,3-dimercaptosuccinic acid (DMSA). (cdc.gov)
  • I N 1948 Warkany and Hubbard 1 indicted mercury ingestion as an etiologic factor in acrodynia. (nap.edu)
  • [1] . Hy neamde de faktor "rat acrodynia factor" of adermine. (wikipedia.org)
  • This graph shows the total number of publications written about "Acrodynia" by people in Harvard Catalyst Profiles by year, and whether "Acrodynia" was a major or minor topic of these publication. (harvard.edu)