Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.Osteolysis, Essential: Syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. The destruction follows various patterns: massive (Gorham disease), multicentric (HAJDU-CHENEY SYNDROME), or carpal/tarsal.Polyethylene: A vinyl polymer made from ethylene. It can be branched or linear. Branched or low-density polyethylene is tough and pliable but not to the same degree as linear polyethylene. Linear or high-density polyethylene has a greater hardness and tensile strength. Polyethylene is used in a variety of products, including implants and prostheses.Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Hip Prosthesis: Replacement for a hip joint.Polyethylenes: Synthetic thermoplastics that are tough, flexible, inert, and resistant to chemicals and electrical current. They are often used as biocompatible materials for prostheses and implants.Arthroplasty, Replacement, Hip: Replacement of the hip joint.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Osteoclasts: A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.Bone Resorption: Bone loss due to osteoclastic activity.Hajdu-Cheney Syndrome: Rare, autosomal dominant syndrome characterized by ACRO-OSTEOLYSIS, generalized OSTEOPOROSIS, and skull deformations.Acetabulum: The part of the pelvis that comprises the pelvic socket where the head of FEMUR joins to form HIP JOINT (acetabulofemoral joint).Aluminum Oxide: An oxide of aluminum, occurring in nature as various minerals such as bauxite, corundum, etc. It is used as an adsorbent, desiccating agent, and catalyst, and in the manufacture of dental cements and refractories.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Hip Joint: The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.RANK Ligand: A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)Skull: The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.Polymethyl Methacrylate: Polymerized methyl methacrylate monomers which are used as sheets, moulding, extrusion powders, surface coating resins, emulsion polymers, fibers, inks, and films (From International Labor Organization, 1983). This material is also used in tooth implants, bone cements, and hard corneal contact lenses.Cementation: The joining of objects by means of a cement (e.g., in fracture fixation, such as in hip arthroplasty for joining of the acetabular component to the femoral component). In dentistry, it is used for the process of attaching parts of a tooth or restorative material to a natural tooth or for the attaching of orthodontic bands to teeth by means of an adhesive.Bone Cements: Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.Coated Materials, Biocompatible: Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.Arthroplasty, Replacement: Partial or total replacement of a joint.Knee Prosthesis: Replacement for a knee joint.Osteoprotegerin: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.Durapatite: The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.Joint Prosthesis: Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)Osteitis: Inflammation of the bone.X-Ray Microtomography: X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.Femur: The longest and largest bone of the skeleton, it is situated between the hip and the knee.Asepsis: The prevention of access by infecting organisms to the locus of potential infection.Chromium Alloys: Specific alloys not less than 85% chromium and nickel or cobalt, with traces of either nickel or cobalt, molybdenum, and other substances. They are used in partial dentures, orthopedic implants, etc.Femur Head: The hemispheric articular surface at the upper extremity of the thigh bone. (Stedman, 26th ed)Receptor Activator of Nuclear Factor-kappa B: A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.Hip Injuries: General or unspecified injuries involving the hip.Osteoarthritis, Hip: Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age. It is characterized by growth or maturational disturbances in the femoral neck and head, as well as acetabular dysplasia. A dominant symptom is pain on weight-bearing or motion.Tarsal Bones: The seven bones which form the tarsus - namely, CALCANEUS; TALUS; cuboid, navicular, and the internal, middle, and external cuneiforms.Osseointegration: The growth action of bone tissue as it assimilates surgically implanted devices or prostheses to be used as either replacement parts (e.g., hip) or as anchors (e.g., endosseous dental implants).Equipment Failure Analysis: The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.Ceramics: Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)Diphosphonates: Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.Angiomatosis: A condition with multiple tumor-like lesions caused either by congenital or developmental malformations of BLOOD VESSELS, or reactive vascular proliferations, such as in bacillary angiomatosis. Angiomatosis is considered non-neoplastic.Foreign-Body Reaction: Chronic inflammation and granuloma formation around irritating foreign bodies.Femur Head Necrosis: Aseptic or avascular necrosis of the femoral head. The major types are idiopathic (primary), as a complication of fractures or dislocations, and LEGG-CALVE-PERTHES DISEASE.Granuloma, Foreign-Body: Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.Tantalum: Tantalum. A rare metallic element, atomic number 73, atomic weight 180.948, symbol Ta. It is a noncorrosive and malleable metal that has been used for plates or disks to replace cranial defects, for wire sutures, and for making prosthetic devices. (Dorland, 28th ed)Osteonecrosis: Death of a bone or part of a bone, either atraumatic or posttraumatic.Cathepsin K: A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.Chylothorax: The presence of chyle in the thoracic cavity. (Dorland, 27th ed)Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Carpal Bones: The eight bones of the wrist: SCAPHOID BONE; LUNATE BONE; TRIQUETRUM BONE; PISIFORM BONE; TRAPEZIUM BONE; TRAPEZOID BONE; CAPITATE BONE; and HAMATE BONE.Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Arthroplasty, Replacement, Knee: Replacement of the knee joint.Clavicle: A bone on the ventral side of the shoulder girdle, which in humans is commonly called the collar bone.Hand Deformities, Acquired: Deformities of the hand, or a part of the hand, acquired after birth as the result of injury or disease.Corrosion: The gradual destruction of a metal or alloy due to oxidation or action of a chemical agent. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
(1/10) Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia.

Mandibuloacral dysplasia (MAD; OMIM 248370) is a rare, genetically and phenotypically heterogeneous, autosomal recessive disorder characterized by skeletal abnormalities including hypoplasia of the mandible and clavicles, acro-osteolysis, cutaneous atrophy and lipodystrophy. A homozygous missense mutation, Arg527His, in the LMNA gene which encodes nuclear lamina proteins lamins A and C has been reported in patients with MAD and partial lipodystrophy. We studied four patients with MAD who had no mutations in the LMNA gene. We now show compound heterozygous mutations, Phe361fsX379 and Trp340Arg, in the zinc metalloproteinase (ZMPSTE24) gene in one of the four patients who had severe MAD associated with progeroid appearance and generalized lipodystrophy. ZMPSTE24 is involved in post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A in two steps to form mature lamin A. Deficiency of Zmpste24 in mice causes accumulation of prelamin A and phenotypic features similar to MAD. The yeast homolog, Ste24, has a parallel role in processing of prenylated mating pheromone a-factor. Since human ZMPSTE24 can also process a-factor when expressed in yeast, we assessed the functional significance of the two ZMPSTE24 mutations in the yeast to complement the mating defect of the haploid MATa yeast lacking STE24 and Ras-converting enzyme 1 (RCE1; another prenylprotein-specific endoprotease) genes. The ZMPSTE24 mutant construct, Phe361fsX379, was inactive in complementing the yeast a-factor but the mutant, Trp340Arg, was partially active compared to the wild type ZMPSTE24 construct. We conclude that mutations in ZMPSTE24 may cause MAD by affecting prelamin A processing.  (+info)

(2/10) Faun tail naevus: a cutaneous marker of spinal dysraphism.

We describe three cases (one male and two females) of faun tail nevi, which is one of the most important cutaneous marker of spinal dysraphism. One of the patients presented with acro-osteolysis leading to auto amputation of the toes of the left foot, which required operative intervention. This lays stress on the early recognition of lumbar paraspinal skin lesions and early treatment to avoid irreversible sequelae.  (+info)

(3/10) Radiological bone lesions in fibroblastic rheumatism; case report.

INTRODUCTION: Fibroblastic rheumatism (FR) is a rare disease characterized by polyarthralgia associated with painless subcutaneous nodules, sclerodactyly and finger contractures. CASE REPORT: A 45-year-old man presented with peripheral vascular disease, polyarthralgia and subcutaneous nodules. The diagnosis of FR was confirmed by histological examination of a biopsy sample of a nodule, which showed myofibroblast proliferation. Radiographs of both hands showed bilateral erosion of the distal and proximal interphalangeal joints, of the right trapezium bone and acro-osteolysis of the third phalanx of the right-hand second finger. COMMENTS: Although the clinical features of FR have now been well described, the literature includes few radiological descriptions. In most reported cases, radiographs are normal at disease onset. Joint radiographs performed later usually show bone destruction of the hands and feet.  (+info)

(4/10) Acro-osteolysis and mononeuritis multiplex as a presenting symptom of systemic angiitis of Wegener's type.

Wegener's granulomatosis is a multisystem disorder involving small- and medium-sized vessels, leading to granuloma formation and involvement of upper and lower respiratory tract with or without glomerulonephritis. However, limited forms of angiitis and granulomatosis of the Wegener's type with oligosymptomatic and atypical site involvement are known to occur. We present here a rare case of limited form of angiitis and granulomatosis of Wegener's type who presented sequentially with spontaneous resorption of digits with acro-osteolysis and mononeuritis multiplex over a period of 10 months. His vasculitic workup revealed high proteinase 3 antibodies (c-ANCA) titers and an almost asymptomatic lung involvement, detected on high-resolution computed tomography of chest. The patient was aggressively treated with immunosuppressive therapy, following which he showed good improvement.  (+info)

(5/10) Type B mandibuloacral dysplasia with congenital myopathy due to homozygous ZMPSTE24 missense mutation.

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(6/10) Osteoblasts from a mandibuloacral dysplasia patient induce human blood precursors to differentiate into active osteoclasts.

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(7/10) Effect of zoledronic acid on acro-osteolysis and osteoporosis in a patient with Hajdu-Cheney syndrome.

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(8/10) Salim Haim and the syndrome that bears his name.

Professor Salim Haim (1919-1983) was a well-known dermatologist. In 1965, Dr. Haim and Dr. Munk, a radiologist, reported a rare congenital type of genodermatosis, later known as Haim-Munk syndrome. This syndrome is characterized by palmoplantar keratosis, pes planus, onychogryphosis, periodontitis, arachnodactyly, and acroosteolysis. This report discusses Haim and Haim-Munk syndrome.  (+info)

*  Acroosteolysis
A mnemonic commonly used for acro-osteolysis is PINCHFO. Pyknodysostosis, Psoriasis, Injury (thermal burn, frostbite), ... Acroosteolysis is resorption of the distal bony phalanges. Acroosteolysis has two patterns of resorption in adults: diffuse and ... Acroosteolysis may be associated with minimal skin changes or with ischemic skin lesions that may result in digital necrosis. ...
*  Haim-Munk syndrome
... (also known as "palmoplantar keratoderma with periodontitis and arachnodactyly and acro-osteolysis") is a ...
*  Wormian bones
Menke's syndrome Cleidocranial dysostosis Hypothyroidism and hypophosphatasia Otopalatodigital syndrome Primary acro-osteolysis ...
*  List of MeSH codes (C05)
... osteolysis MeSH C05.116.264.579.052 --- acro-osteolysis MeSH C05.116.264.579.052.400 --- hajdu-cheney syndrome MeSH C05.116. ... File "2006 MeSH Trees".) MeSH C05.116.070.265 --- bone cysts, aneurysmal MeSH C05.116.099.052 --- acro-osteolysis MeSH C05.116. ... osteolysis, essential MeSH C05.116.099.742 --- platybasia MeSH C05.116.099.750 --- proteus syndrome MeSH C05.116.132.082 --- ... 264.579.704 --- osteolysis, essential MeSH C05.116.540.310 --- exostoses MeSH C05.116.540.310.500 --- exostoses, multiple ...
*  List of syndromes
... ectodermal dysplasia Hypoplastic left heart syndrome Hypoplastic right heart syndrome Hypotonia Hypotrichosis-acro-osteolysis- ... microphthalmia and cataract syndrome Acrocallosal syndrome Acropectoral syndrome Acro-dermato-ungual-lacrimal-tooth syndrome ...
*  Singleton Merten syndrome
... acro-osteolysis, and equinovarus foot deformities. Singleton, EB, Merten DF: An unusual syndrome of widened medullary cavities ...
*  List of cutaneous conditions
Hypotrichosis-acro-osteolysis-onychogryphosis-palmoplantar keratoderma-periodontitis syndrome Hypotrichosis-lymphedema- ... palmoplantar keratoderma with periodontitis and arachnodactyly and acro-osteolysis) Hidrotic ectodermal dysplasia (alopecia ... Acroosteolysis Acute paronychia Alopecia areata Alopecia neoplastica Anagen effluvium Androgenic alopecia (androgenetic ... Nodulosis-arthropathy-osteolysis syndrome Normophosphatemic familial tumoral calcinosis Palisaded neutrophilic and ...
*  Dynamit Nobel
... finger circulation disorder resulting in acro-osteolysis (necrosis of the first phalanxes), as well as headaches and dizziness ...
Hajdu-Cheney syndrome | Radiology Reference Article | Radiopaedia.org  Hajdu-Cheney syndrome | Radiology Reference Article | Radiopaedia.org
It is associated with osteoporosis, bony deformities and acro-osteolysis. It follows an autosomal dominant inheritance but can ... These involve other causes of acro-osteolysis and can be differentiated radiologically 5. Amongst others, they include the ... acro-osteolysis. *transverse band of osteolysis in distal phalanges is characteristic. *distal to proximal osteolysis is also ...
more infohttps://radiopaedia.org/articles/hajdu-cheney-syndrome-1
Acroosteolysis - Wikipedia  Acroosteolysis - Wikipedia
A mnemonic commonly used for acro-osteolysis is PINCHFO. Pyknodysostosis, Psoriasis, Injury (thermal burn, frostbite), ... Acroosteolysis is resorption of the distal bony phalanges. Acroosteolysis has two patterns of resorption in adults: diffuse and ... Acroosteolysis may be associated with minimal skin changes or with ischemic skin lesions that may result in digital necrosis. ...
more infohttps://en.wikipedia.org/wiki/Acroosteolysis
Acro-osteolysis | Radiology Reference Article | Radiopaedia.org  Acro-osteolysis | Radiology Reference Article | Radiopaedia.org
Acro-osteolysis refers to resorption of the distal phalanx. The terminal tuft is most commonly affected but the shaft of the ... Acro-osteolysis refers to resorption of the distal phalanx. The terminal tuft is most commonly affected but the shaft of the ...
more infohttps://radiopaedia.org/articles/acro-osteolysis-1
Acroosteolysis dominant type             | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program  Acroosteolysis dominant type | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
... information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Acroosteolysis ... Loss of bone (osteolysis) in the hands and feet is a characteristic feature of this condition. Other features of AOD may ... Acroosteolysis dominant type Title Other Names:. Acroosteolysis with osteoporosis and changes in skull and mandible; ... Acroosteolysis dominant type is caused by mutations. in the NOTCH2 gene. . It is inherited. in an autosomal dominant. manner. ...
more infohttps://rarediseases.info.nih.gov/diseases/508/acroosteolysis-dominant-type
Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease - American Family Physician  Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease - American Family Physician
Acro-osteolysis. Digital pitting or ulceration. Pterygium inversus unguis (i.e., distal nail bed adherence to the ventral ...
more infohttps://www.aafp.org/afp/2008/1015/p961.html
Diagnostic Radiology/Musculoskeletal Imaging/Joint Disorders/Scleroderma - Wikibooks, open books for an open world  Diagnostic Radiology/Musculoskeletal Imaging/Joint Disorders/Scleroderma - Wikibooks, open books for an open world
No treatment for acroosteolysis. The treatment for scleroderma varies depending on organ involvement and is beyond the scope of ... though osteolysis in other sites (feet, ribs, and mandibles) was also frequent. Nearly 20% showed radiographic evidence of ... Radiographic findings in the extremities include acroosteolysis, soft tissue calcifications (calcinosis), and atrophy of the ... The differential diagnosis for acroosteolysis includes diseases that affect peripheral nerve sensation such as diabetes, ...
more infohttps://en.wikibooks.org/wiki/Diagnostic_Radiology/Musculoskeletal_Imaging/Joint_Disorders/Scleroderma
The many symptoms of pachydermoperiostosis  The many symptoms of pachydermoperiostosis
Acro-osteolysis is also reported. The differential diagnosis includes secondary HOA, acromegaly, thyroid acropachy and ...
more infohttp://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742010000400012&lng=es&nrm=iso&tlng=en
Wordsworth P[au] - PubMed - NCBI  Wordsworth P[au] - PubMed - NCBI
A new acro-osteolysis syndrome caused by duplications including PTHLH.. Gray MJ, van Kogelenberg M, Beddow R, Morgan T, ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Wordsworth+P%5Bau%5D&dispmax=50
Bone symptoms - RightDiagnosis.com  Bone symptoms - RightDiagnosis.com
Acro coxo mesomelic dysplasia ... dwarfism, dislocated hips, delayed bone age*Acro-pectoro-renal field defect ... pectus ... Familial Expansile Osteolysis ... bone deformity*Folate deficiency ... spina bifida*Friedreich's ataxia ... scoliosis. G. * ... Acroosteolysis dominant type ... skull deformity*Acroosteolysis neurogenic ... tapered fingers, bone degeneration in legs, coxa ... Acro-reno-ocular syndrome ... polydactyly*Acrocallosal syndrome ... tapered fingers*Acrocapitofemoral dysplasia ... narrow ...
more infohttps://www.rightdiagnosis.com/sym/bone_symptoms.htm
Prevalence of Causes of Symptom: Finger symptoms  - RightDiagnosis.com  Prevalence of Causes of Symptom: Finger symptoms - RightDiagnosis.com
Acro-pectoro-renal field defect... missing fingers , extra fingers*Acro-reno-ocular syndrome... polydactyly *Acrocallosal ... Nodulosis-arthropathy-osteolysis syndrome... camptodactyly *Non-hereditary spherocytic anemia... brittle nails *Normochromic ... Acroosteolysis neurogenic... abnormal nails , thick fingernails, tapered fingers, abnormal fingernails*Acropectoral syndrome ... Multicentric osteolysis -- nodulosis -- arthropathy... camptodactyly *Multiple pterygium syndrome... syndactyly , camptodactyly ...
more infohttps://www.rightdiagnosis.com/symptoms/finger_symptoms.htm
Human Genetics of Pain - Oxford Handbooks  Human Genetics of Pain - Oxford Handbooks
Giaccai, L. (1952). Familial and sporadic neurogenic acro-osteolysis. Acta Radiology, 38(1), 17-29.Find this resource: ...
more infohttps://www.oxfordhandbooks.com/view/10.1093/oxfordhb/9780190860509.001.0001/oxfordhb-9780190860509-e-1
Nestor-guillermo progeria syndrome             | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program  Nestor-guillermo progeria syndrome | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
is a rare, genetic, progeroid syndrome characterized by a prematurely aged appearance associated with severe osteolysis ( ... Progressive clavicular acroosteolysis. 0000905 Proptosis. Bulging eye Eyeballs bulging out Prominent eyes ...
more infohttps://rarediseases.info.nih.gov/diseases/11008/nestor-guillermo-progeria-syndrome
Patient Stories  Patient Stories
X-rays confirmed that she has acro-osteolysis. She is the only known case in the world with her symptoms and no one knows the ...
more infohttp://www.bcchf.ca/events/event-calendar/lace-up-for-kids/patient-stories/
Imaging in Hypertrophic Osteoarthropathy: Overview, Radiography, Computed Tomography  Imaging in Hypertrophic Osteoarthropathy: Overview, Radiography, Computed Tomography
Note the soft-tissue clubbing and acro-osteolysis of the terminal phalanges. View Media Gallery ... Note the soft-tissue clubbing and acro-osteolysis of the terminal phalanges. View Media Gallery ... Note the soft-tissue clubbing and acro-osteolysis of the terminal phalanges. ...
more infohttps://emedicine.medscape.com/article/390998-overview
A - Health Conditions - Genetics Home Reference - NIH  A - Health Conditions - Genetics Home Reference - NIH
acroosteolysis dominant type, see Hajdu-Cheney syndrome. *acroosteolysis with osteoporosis and changes in skull and mandible, ... Al-Aqeel Sewairi syndrome, see Multicentric osteolysis, nodulosis, and arthropathy. *Alacrima-achalasia-adrenal insufficiency ...
more infohttps://ghr.nlm.nih.gov/condition
Winchester Syndrome: Background, Pathophysiology, Etiology  Winchester Syndrome: Background, Pathophysiology, Etiology
Idiopathic multicentric osteolysis: report of two new cases and a review of the literature. Am J Med Genet. 1988 Apr. 29(4):929 ... Kozlowski K, Barylak A, Eftekhari F, Pasyk K, Wislocka E. Acroosteolysis. Problems of diagnosis--report of four cases. Pediatr ... The diagnosis and management of patients with idiopathic osteolysis. Pediatr Rheumatol Online J. 2011 Oct 13. 9:31. [Medline]. ... 14] Torg syndrome, nodulosis-arthropathy-osteolysis, and Winchester syndrome may be allelic disorders. [15] These 2 syndromes ...
more infohttps://emedicine.medscape.com/article/1116154-overview
Bone, Joints, and Soft Tissues | Springer for Research & Development  Bone, Joints, and Soft Tissues | Springer for Research & Development
Destouet JM, Murphy WA: Acquired acroosteolysis and acronecrosis. Arthritis Rheum 1983; 26: 1150-1154PubMedCrossRefGoogle ... Rsenick D, Weisman M, Goergen TG, et al: Osteolysis with detritic synovitis: A new syndrome. Arch Intern Med 1978; 138: 1003- ...
more infohttps://rd.springer.com/chapter/10.1007/978-1-4757-2269-7_4
  • Reported associated features include e.g.: acro-osteolysis, sparse facial and pubic hair, gynaecomastia, seborrhoea of the face and scalp, palmoplantar hyperhidrosis, carpal and tarsal tunnel syndrome, and learning difficulties. (blogspot.com)