Acquired hyperostosis syndrome. Medical search

Increase in the mass of bone per unit volume.

Syndrome consisting of SYNOVITIS; ACNE CONGLOBATA; PALMOPLANTAR PUSTULOSIS; HYPEROSTOSIS; and OSTEITIS. The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.

A disease of elderly men characterized by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions.

Thickening of the inner table of the frontal bone, which may be associated with hypertrichosis and obesity. It most commonly affects women near menopause.

A rare, benign rheumatologic disorder or syndrome characterized by hyperostosis and soft tissue ossification between the clavicles and the anterior part of the upper ribs. It is often associated with the dermatologic disorder palmoplantar pustulosis, particularly in Japan. Careful diagnosis is required to distinguish it from psoriatic arthritis, OSTEITIS DEFORMANS, and other diseases. Spondylitis of pustulosis palmaris et plantaris is one of the possible causes; also, evidence suggests one origin may be bone infection. Bone imaging is especially useful for diagnosis. It was originally described by Sonozaki in 1974.

Benign hypertrophy that projects outward from the surface of bone, often containing a cartilaginous component.

A characteristic symptom complex.

A form of osteosclerosis extending in a linear track mainly through one of the long bones of the upper and lower limbs.

Fixation and immobility of a joint.

The study of disease in prehistoric times as revealed in bones, mummies, and archaeologic artifacts.

A mucosal tumor of the urinary bladder or nasal cavity in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded than in other papillomas. (Stedman, 25th ed)

Inflammation of the bone.

A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Outgrowth of immature bony processes or bone spurs (OSTEOPHYTE) from the VERTEBRAE, reflecting the presence of degenerative disease and calcification. It commonly occurs in cervical and lumbar SPONDYLOSIS.

Air-filled spaces located within the bones around the NASAL CAVITY. They are extensions of the nasal cavity and lined by the ciliated NASAL MUCOSA. Each sinus is named for the cranial bone in which it is located, such as the ETHMOID SINUS; the FRONTAL SINUS; the MAXILLARY SINUS; and the SPHENOID SINUS.

The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.

The first seven VERTEBRAE of the SPINAL COLUMN, which correspond to the VERTEBRAE of the NECK.

A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)

The bone of the lower leg lateral to and smaller than the tibia. In proportion to its length, it is the most slender of the long bones.

Tumors or cancer of the PARANASAL SINUSES.

A long, narrow, and flat bone commonly known as BREASTBONE occurring in the midsection of the anterior thoracic segment or chest region, which stabilizes the rib cage and serves as the point of origin for several muscles that move the arms, head, and neck.

Two extensive fibrous bands running the length of the vertebral column. The anterior longitudinal ligament (ligamentum longitudinale anterius; lacertus medius) interconnects the anterior surfaces of the vertebral bodies; the posterior longitudinal ligament (ligamentum longitudinale posterius) interconnects the posterior surfaces. The commonest clinical consideration is OSSIFICATION OF POSTERIOR LONGITUDINAL LIGAMENT. (From Stedman, 25th ed)

Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.

Neoplasms of the base of the skull specifically, differentiated from neoplasms of unspecified sites or bones of the skull (SKULL NEOPLASMS).

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Tumors or cancer of the NOSE.

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)

An abnormal hardening or increased density of bone tissue.

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A specified list of terms with a fixed and unalterable meaning, and from which a selection is made when CATALOGING; ABSTRACTING AND INDEXING; or searching BOOKS; JOURNALS AS TOPIC; and other documents. The control is intended to avoid the scattering of related subjects under different headings (SUBJECT HEADINGS). The list may be altered or extended only by the publisher or issuing agency. (From Harrod's Librarians' Glossary, 7th ed, p163)

Controlled vocabulary of clinical terms produced by the International Health Terminology Standards Development Organisation (IHTSDO).

Time period from 1901 through 2000 of the common era.

A research and development program initiated by the NATIONAL LIBRARY OF MEDICINE to build knowledge sources for the purpose of aiding the development of systems that help health professionals retrieve and integrate biomedical information. The knowledge sources can be used to link disparate information systems to overcome retrieval problems caused by differences in terminology and the scattering of relevant information across many databases. The three knowledge sources are the Metathesaurus, the Semantic Network, and the Specialist Lexicon.

Terms or expressions which provide the major means of access by subject to the bibliographic unit.

Descriptive terms and identifying codes for reporting medical services and procedures performed by PHYSICIANS. It is produced by the AMERICAN MEDICAL ASSOCIATION and used in insurance claim reporting for MEDICARE; MEDICAID; and private health insurance programs (From CPT 2002).

The return of a sign, symptom, or disease after a remission.

Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)

A neurovascular syndrome associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the superior thoracic outlet. This may result from a variety of anomalies such as a CERVICAL RIB, anomalous fascial bands, and abnormalities of the origin or insertion of the anterior or medial scalene muscles. Clinical features may include pain in the shoulder and neck region which radiates into the arm, PARESIS or PARALYSIS of brachial plexus innervated muscles, PARESTHESIA, loss of sensation, reduction of arterial pulses in the affected extremity, ISCHEMIA, and EDEMA. (Adams et al., Principles of Neurology, 6th ed, pp214-5).

Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)

A condition associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the thoracic outlet and caused by a complete or incomplete anomalous CERVICAL RIB or fascial band connecting the tip of a cervical rib with the first thoracic rib. Clinical manifestations may include pain in the neck and shoulder which radiates into the upper extremity, PARESIS or PARALYSIS of brachial plexus innervated muscles; sensory loss; PARESTHESIAS; ISCHEMIA; and EDEMA. (Adams et al., Principles of Neurology, 6th ed, p214)

A set of twelve curved bones which connect to the vertebral column posteriorly, and terminate anteriorly as costal cartilage. Together, they form a protective cage around the internal thoracic organs.

A supernumerary rib developing from an abnormal enlargement of the costal element of the C7 vertebra. This anomaly is found in 1-2% of the population and can put pressure on adjacent structures causing CERVICAL RIB SYNDROME; THORACIC OUTLET SYNDROME; or other conditions.

A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)

Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)

Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.

Proteins prepared by recombinant DNA technology.

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.

The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

SAPHO syndrome of the temporomandibular joint associated with sudden deafness. (1/31)

We report a case of arthritis of the temporomandibular joint (TMJ) associated with sclerosing osteomyelitis of the mandible and temporal bone, causing deafness. The presence of a palmoplantar pustulosis established the diagnosis of SAPHO syndrome. SAPHO (an acronym referring to synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis) syndrome is defined by the association of characteristic osteoarticular and dermatologic manifestations, with diffuse sclerosing osteomyelitis of the mandible being a part of this entity. We review the literature of SAPHO syndrome with mandibular manifestations and discuss the mechanisms of inflammatory spread from the TMJ to the cochlea. To our knowledge, this is the first description of skull base involvement in a patient with SAPHO syndrome leading to sudden deafness. (+info)

SAPHO syndrome or psoriatic arthritis? A familial case study. (2/31)

OBJECTIVE: To discuss the relationships between SAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome and the group of spondylarthropathies. METHODS: Few reports of familial SAPHO have been published. We describe three children, two sisters and one brother, whose clinical and radiological presentation was in accordance with SAPHO syndrome. RESULTS: Two children developed psoriasis, and one child palmoplantar pustulosis. Both sacroiliac and sternoclavicular joints were involved in these three cases. Some features in our observations are also common to psoriatic arthritis. No association was found with HLA antigens, but a history of trauma preceding the onset of symptoms was present in all three children. CONCLUSIONS: We can consider that SAPHO is nosologically related to spondylarthropathies. Psoriatic arthritis could be the missing link between SAPHO and spondylarthropathies. It is likely that both genetic and environmental factors are involved. (+info)

Diagnostic points and possible origin of osteomyelitis in synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome: a radiographic study of 77 mandibular osteomyelitis cases. (3/31)

OBJECTIVES: To find diagnostic points and to identify the origin of osteomyelitis in synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome. METHODS: Fifty-two patients with mandibular suppurative osteomyelitis and 25 patients with mandibular osteomyelitis in SAPHO syndrome were included in the study. Radiographic patterns of the lesion, types of periosteal reaction and the presence of external bone resorption and bone enlargement were investigated in each case and compared between the two entities. RESULTS: Suppurative osteomyelitis demonstrated an osteolytic pattern and a lamellated type of periosteal reaction, whereas SAPHO syndrome revealed a mixed-pattern, solid-type periosteal reaction, external bone resorption and bone enlargement. CONCLUSIONS: Radiographic examination is suggested to be convenient and a useful diagnostic method of differentiating osteomyelitis in SAPHO syndrome from suppurative osteomyelitis. The periosteum is suspected to be the original site of osteomyelitic lesions in SAPHO syndrome. (+info)

SAPHO syndrome treated with pamidronate: an open-label study of 10 patients. (4/31)

BACKGROUND: In recent years the SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) has been encountered more frequently. However, clinical evidence indicating superiority of a specific therapeutic modality is still absent. Pamidronate, a second-generation bisphosphonate, has a pronounced effect on bone metabolism by suppressing bone resorption. We report our clinical experience with intravenous pamidronate in SAPHO syndrome. METHODS: Between the years 1999 and 2003 we treated 10 patients with the SAPHO syndrome who did not respond to NSAIDs, oral corticosteroids, colchicine, methotrexate, sulphasalazine or infliximab. All patients were treated with 60 mg pamidronate, given intravenously within an hour. In cases of no response a subsequent dose was given within a month and if there was a partial response an additional infusion was given after 4 months. The primary endpoint was the disappearance of recurrent bouts of bone pain, osteitis or hyperostosis, or recurrent synovitis. Reduction of the frequency of attacks by 50% was regarded as a partial response. RESULTS: Seven of the patients were females and three were males. The age at diagnosis ranged from 26 to 68 yr. All patients had axial or peripheral arthritis and cutaneous involvement; three had severe acne, eight had pustulosis and two had concomitant psoriasis vulgaris. Hyperostosis of the anterior chest wall involving either sternocostal or sternoclavicular joints, as seen on technetium 99 bone scintigraphy, was detected in all patients. Complete remission was observed following therapy in six patients, three others partially responded and only one patient had no response. Two patients needed four cycles of pamidronate infusion, one patient needed three, six needed two infusions and one patient remitted following a single pamidronate infusion. In all but one patient pamidronate was effective in preventing recurrent bouts of pustulosis. CONCLUSION: Pamidronate seems to be a very effective mode of therapy for patients with the SAPHO syndrome, by promoting remission in all components of the disorder, such as bone, joint and skin involvement, and ceases the bouts that characterize this disorder. (+info)

Pamidronate in the treatment of childhood SAPHO syndrome. (5/31)

BACKGROUND: SAPHO syndrome is increasingly recognized within the paediatric population. Conventional therapeutic approaches have often not been effective. Pamidronate is a second-generation bisphosphonate that affects bone turnover and demonstrates anti-inflammatory properties. In small case series it has given symptomatic relief to adults with this condition. OBJECTIVES: To report the clinical experience with pamidronate in childhood SAPHO syndrome. METHODS: A retrospective observational study of all children with SAPHO syndrome treated with pamidronate between 1996 and 2003 at a tertiary rheumatology centre. The standard dosing regime for pamidronate was 1 mg/kg to a maximum of 30 mg, administered daily for three consecutive days, repeated 3-monthly as required. Response to treatment was determined by clinical observation, patient subjective response and reduction in other treatments RESULTS: Seven girls were treated, with a median (range) age at diagnosis of 11 yr (9-15 yr). All patients demonstrated a beneficial clinical response, with relief of pain, increased activity and improved well-being. Subsequent courses of pamidronate were used in all patients. Other medications including corticosteroids and methotrexate could subsequently be stopped. Transient symptoms were associated with the initial course of pamidronate in some patients. No serious adverse events were reported. CONCLUSIONS: Pamidronate was associated with a marked improvement in function and well-being, and a reduction of pain and use of other medications in all patients, with no significant adverse effects. This study represents preliminary clinical data. A prospective multicentre study is necessary to assess the role and long-term safety of pamidronate in the management of childhood SAPHO syndrome (+info)

Successful treatment of SAPHO syndrome with zoledronic acid. (6/31)

The SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) is a chronic, relapsing, inflammatory condition with skin and osteoarticular manifestations. Its etiology remains unclear, and various treatment regimens with steroids and nonsteroidal antiinflammatory drugs frequently fail to control the disease, while exposing patients to the side effects of these drugs. Because the SAPHO syndrome manifests as a destructive inflammatory bone disease, use of bisphosphonates that possess antiosteoclastic and probably antiinflammatory properties has been suggested to be helpful. To our knowledge, this is the first reported case of successful treatment with zoledronic acid of SAPHO syndrome that was resistant to conventional treatment. (+info)

Isolated thoracic spine lesion: is this the presentation of a SAPHO syndrome? A case report. (7/31)

A case of an isolated lesion of the thoracic spine attributed to SAPHO syndrome is presented. A 51-year-old man was referred for inflammatory pain in the thoracic spine. The general examination was normal (especially cutaneous and rheumatologic examinations). Laboratory analysis showed only a mild inflammatory reaction. Standard radiographs showed partial condensation of T8. Computed tomography showed osteolysis of the anterior corner of T8, and MRI revealed an abnormal signal of T8, with enlargement of the prevertebral soft tissue. Percutaneous and thoracoscopic biopsies showed a nonspecific inflammatory process, and cultures were sterile. Initially, several diagnoses were advanced: infectious spondylitis, malignant tumor, lymphomas, Paget disease, seronegative spondyloarthropathies and finally atypical SAPHO syndrome. Three months later, the patient experienced more pain. General examination was still normal. The radiological findings worsened, while the inflammatory blood tests were normal. A new thoracoscopic biopsy revealed a nonspecific inflammatory process. A diagnosis of SAPHO syndrome was made, despite the lack of typical lesions. Dramatically improving with anti-inflammatory therapy, the patient's condition was favorable at 3-year follow-up. This atypical presentation of an isolated lesion in the spine makes the diagnosis of a SAPHO syndrome difficult but possible. Spine surgeons must be aware of this rare entity, to avoid misdiagnosis and unnecessary repeated surgical biopsies. (+info)

The usefulness of bone remodelling markers in predicting the efficacy of pamidronate treatment in SAPHO syndrome. (8/31)

OBJECTIVES: Pamidronate has recently been used in SAPHO syndrome due to its anti-osteoclastic effect. The aim of this study is to determine the usefulness of bone remodelling markers for determining the efficacy of pamidronate treatment. METHODS: Thirteen patients with SAPHO syndrome were treated with pamidronate. The treatment evaluation was done using a visual analogue scale (VAS) and also erythrocyte sedimentation rate, C-reactive protein, serum crosslaps (sCTX) and osteocalcin initially and after 3 months. A relevant clinical response was defined as an improvement in VAS of at least 40%. RESULTS: At 3 months, 7 of 13 patients had a good clinical response, as previously defined. Five of the seven patients maintained the good response over 6 months. Before the first perfusion 6 of the 13 patients had increased sCTX (upper 3250 pmol/l). In this small cohort we tried to analyse whether the increase in bone remodelling markers was associated with a good clinical response. In the responders group the mean levels of sCTX and osteocalcin at baseline were 6783.17 and 24.66, respectively, and in the non-responders group the levels were 2152 and 11.8, respectively. There was a significant difference in sCTX between the responders and the non-responders (P = 0.0044). CONCLUSION: Infusion of pamidronate is effective in SAPHO in some patients. Increased sCTX might be a prognostic marker for a good clinical response but results have to be confirmed in a larger cohort. (+info)

Rarer acquired causes include tumors (especially pancoast tumor), hyperostosis, and osteomyelitis Adson's sign and the ... Cervical rib syndrome (compression on brachial plexus and/or subclavian artery caused by bone growth). Costoclavicular syndrome ... Thoracic outlet syndrome (TOS) is a condition in which there is compression of the nerves, arteries, or veins in the passageway ... "Thoracic outlet syndrome". Mount Sinai Hospital, New York. Archived from the original on December 9, 2008. Ambrad-Chalela E, ...

https://en.wikipedia.org/wiki/Thoracic_outlet_syndrome

... acquired hyperostosis syndrome MeSH C05.116.099.708.857 - short rib-polydactyly syndrome MeSH C05.116.099.708.914 - ... Klippel-Feil syndrome MeSH C05.116.099.370.652 - orofaciodigital syndromes MeSH C05.116.099.370.797 - Rubinstein-Taybi syndrome ... hyperostosis frontalis interna MeSH C05.116.099.708.582 - Langer-Giedion syndrome MeSH C05.116.099.708.670 - osteochondroma ... Hajdu-Cheney syndrome MeSH C05.116.099.105 - basal-cell nevus syndrome MeSH C05.116.099.343 - dwarfism MeSH C05.116.099.343.110 ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C05)

738 Other acquired deformity 738.0 Acquired deformity of nose 738.1 Other acquired deformity of head 738.2 Acquired deformity ... 710 Diffuse diseases of connective tissue 710.0 Systemic lupus erythematosus 710.2 Sjögren's syndrome 710.3 Dermatomyositis ... myelopathy 721.5 Kissing spine 721.6 Ankylosing vertebral hyperostosis 721.7 Traumatic spondylopathy 722 Intervertebral disc ... acquired) 736.89 Other acquired deformity of other parts of limb Winged scapula 736.9 Acquired deformity, limb, unspec. 737 ...

https://en.wikipedia.org/wiki/List_of_ICD-9_codes_710–739:_diseases_of_the_musculoskeletal_system_and_connective_tissue

... hyperostosis, osteitis) syndrome, sarcoidosis and sciatica. It is also suspected a main bacterial source of neuroinflammation ... The antibiotic families that C. acnes are most likely to acquire resistance to are the macrolides (e.g., erythromycin and ...

https://en.wikipedia.org/wiki/Cutibacterium_acnes

Acquired generalized lipodystrophy (Lawrence syndrome, Lawrence-Seip syndrome) Adiposis dolorosa (Dercum's disease) Alpha-1 ... Rosacea conglobata Synovitis-acne-pustulosis-hyperostosis-osteomyelitis syndrome (SAPHO syndrome) Steroid rosacea Tar acne ... Turner syndrome Ulnar-mammary syndrome Van Der Woude syndrome Von Hippel-Lindau syndrome Watson syndrome Werner syndrome (adult ... Freeman-Sheldon syndrome, Windmill-Vane-Hand syndrome) Wilson-Turner syndrome Wolf-Hirschhorn syndrome (4p- syndrome) X-linked ...

https://en.wikipedia.org/wiki/List_of_skin_conditions

... homocitrullinuria syndrome Hyperostosid corticalis deformans juvenilis Hyperostosis cortical infantile Hyperostosis corticalis ... acquired Hypertrichosis retinopathy dysmorphism Hypertrichosis, anterior cervical Hypertrichotic osteochondrodysplasia ... Mcdonald syndrome Hunter-Jurenka-Thompson syndrome Hunter-Macpherson syndrome Hunter-Mcalpine syndrome Hunter-Mcdonald syndrome ... child Heavy metal poisoning HEC syndrome Hecht-Scott syndrome Heckenlively syndrome Heide syndrome Heliophobia HELLP syndrome ...

https://en.wikipedia.org/wiki/List_of_diseases_(H)

Acquired agranulocytosis Acquired central hypoventilation syndrome Acquired hypoprothrombinemia Acquired ichthyosis Acquired ... Ankyloglossia heterochromia clasped thumbs Ankylosing spondylarthritis Ankylosing spondylitis Ankylosing vertebral hyperostosis ... Pande syndrome Aarskog syndrome Aase-Smith syndrome Aase syndrome Abasia ABCD syndrome Abdallat-Davis-Farrage syndrome ... syndrome Akesson syndrome Aksu-Stckhausen syndrome Al Awadi Teebi Farag syndrome Al Frayh Facharzt Haque syndrome Al Gazali Al ...

https://en.wikipedia.org/wiki/List_of_diseases_(A)

... tethered spinal cord syndrome, and connective tissue disorders such as Ehlers-Danlos syndrome and Marfan syndrome. Chiari ... O'Shaughnessy BA, Bendok BR, Parkinson RJ, Shaibani A, Walker MT, Shakir E, Batjer HH (January 2006). "Acquired Chiari ... Congenital causes include hydrocephalus, craniosynostosis (especially of the lambdoid suture), hyperostosis (such as ... Chiari malformation or Arnold-Chiari malformation should not be confused with Budd-Chiari syndrome, a hepatic condition also ...

https://en.wikipedia.org/wiki/Chiari_malformation

... chronic spasmodic Dysplasia epiphysealis hemimelica Dysplasia Dysplastic cortical hyperostosis Dysplastic nevus syndrome ... acquired Dysgerminoma Dysgraphia Dysharmonic skeletal maturation muscular fiber disproportion Dyskeratosis congenita of Zinsser ... syndrome Daneman-Davy-Mancer syndrome Darier's disease Davenport-Donlan syndrome David syndrome Davis-Lafer syndrome De Barsy ... Salih-Patel syndrome Dinno-Shearer-Weisskopf syndrome Diomedi-Bernardi-Placidi syndrome Dionisi-Vici-Sabetta-Gambarara syndrome ...

https://en.wikipedia.org/wiki/List_of_diseases_(D)

Cohen and Tibbles said that Merrick showed the following signs of Proteus syndrome: "macrocephaly; hyperostosis of the large ... there is evidence to suggest that Merrick acquired this particular costume a year later, while travelling with Sam Roper's Fair ... Only in 1986 was it conjectured that he had Proteus syndrome, a very rare congenital disorder also known as Wiedemann syndrome ... Tibbles, J. A. R.; Cohen, M. M. (1986), "The Proteus Syndrome: The Elephant Man Diagnosed", British Medical Journal, 293 (6548 ...

https://en.wikipedia.org/wiki/Elephant_Man

Cohen and Tibbles said Merrick showed the following signs of Proteus syndrome: "macrocephaly; hyperostosis of the large skull; ... there is evidence to suggest that Merrick acquired this particular costume a year later, while travelling with Sam Roper's Fair ... In fact, Proteus syndrome affects tissue other than nerves, and it is a sporadic disorder rather than a genetically transmitted ... In 1986 it was conjectured that he had Proteus syndrome. DNA tests on his hair and bones in a 2003 study were inconclusive. ...

https://en.wikipedia.org/wiki/Joseph_Merrick

Towards the end of the 14th century, the abbey acquired a "giant" statue of Saint Christopher. Three wills from members of the ... The only major congenital abnormality found consisted of bony changes resulting from a possible case of Down's syndrome. ... Other diseases specific to bones and joints were osteoarthritis, diffuse idiopathic skeletal hyperostosis (DISH), and possible ... and three crania had features of hyperostosis frontalis interna, a metabolic condition affecting post-menopausal women. ...

https://en.wikipedia.org/wiki/Norton_Priory

MAT1A Hyperornithinemia-hyperammonemia-homocitrullinemia syndrome; 238970; SLC25A15 Hyperostosis, endosteal; 144750; LRP5 ... acquired; 608709; LMNB2 Lipoid adrenal hyperplasia; 201710; STAR Lipoid congenital adrenal hyperplasia; 201710; CYP11A Lipoid ... AKAP9 Long QT syndrome-3; 603830; SCN5A Long QT syndrome-4; 600919; ANK2 Long QT syndrome-7; 170390; KCNJ2 Long QT syndrome-9; ... TGFBR2 Long QT syndrome 12; 612955; SNT1 Long QT syndrome 13; 613485; KCNJ5 Long QT syndrome-1; 192500; KCNQ1 Long QT syndrome- ...

https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes

Acquired Hyperostosis Syndrome. Syndrome. Disease. Pathologic Processes. Osteochondrodysplasias. Bone Diseases, Developmental. ... Efficacy of Bisphosphonates in Patients With Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome. The ... Hyperostosis (of the anterior chest wall, limbs or spine) with or without dermatosis ... Genetic and Rare Diseases Information Center resources: Synovitis SAPHO Syndrome Mucopolysaccharidosis Type IV ...

https://www.clinicaltrials.gov/ct2/show/NCT02544659

Acquired Hyperostosis Syndrome Synonyms Acquired Hyperostosis Syndromes , Hyperostosis Syndrome, Acquired , Hyperostosis ... Acquired , SAPHO Syndrome , SAPHO Syndromes , Syndrome, Acquired Hyperostosis , Syndromes, Acquired Hyperostosis , Syndrome, ... SAPHO , Syndromes, SAPHO , Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis Definition Syndrome consisting of ... The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.. ...

http://ctdbase.org/detail.go?type=disease&acc=MESH%3AD020083

"Acquired Hyperostosis Syndrome" by people in this website by year, and whether "Acquired Hyperostosis Syndrome" was a major or ... Acquired Hyperostosis Syndrome*Acquired Hyperostosis Syndrome. *Acquired Hyperostosis Syndromes. *Hyperostosis Syndrome, ... "Acquired Hyperostosis Syndrome" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Acquired Hyperostosis Syndrome" by people in Profiles. ...

https://profiles.uchicago.edu/profiles/display/31399

Acquired Hyperostosis Syndrome [‎1]‎. Acquired Immunodeficiency Syndrome [‎81]‎. Adolescent Health [‎1]‎. Adolescent Health ...

https://apps.who.int/iris/handle/10665/113217/browse?type=mesh

MalaCards based summary : Sapho Syndrome, also known as acquired hyperostosis syndrome, is related to osteomyelitis and ... Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome 73 Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis ... MalaCards integrated aliases for Sapho Syndrome:. Name: Sapho Syndrome 12 76 53 59 15 ... Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome - AA challenging diagnosis not to be missed. ( ...

https://www.malacards.org/card/sapho_syndrome

... information resources and questions answered by our Genetic and Rare Diseases Information Specialists for SAPHO syndrome ... Acquired hyperostosis syndrome; Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis; Synovitis acne pustulosis ... Visit the following Facebook groups related to SAPHO syndrome:. SAPHO Syndrome Support. Sapho syndrome. SAPHO Syndrome UK. ... syndrome. involves any combination of: Synovitis (inflammation of the joints), Acne, Pustulosis (thick yellow blisters ...

https://rarediseases.info.nih.gov/diseases/7606/sapho-syndrome

Acquired Immunodeficiency Syndrome51. *Retroviridae37. *HIV30. *Acquired Hyperostosis Syndrome3 ...

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208000007815 Acquired Hyperostosis Syndrome Diseases 0 description 3 * 102000001714 Agammaglobulinaemia Tyrosine Kinase Human ...

https://patents.google.com/patent/US20150133403A1/en

Syndrome - Two Presentations of the Same Disease? were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad. ... Acquired Hyperostosis SyndromeAdolescentChildChild, PreschoolDiagnosis, DifferentialFemaleHumansMaleOsteomyelitisRetrospective ... Imaging for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome.. *The SAPHO syndrome: defining the ... Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome in childhood: a report of ten cases and review of the ...

https://www.unboundmedicine.com/medline/citation/30390722/Chronic_Recurrent_Multifocal_Osteomyelitis_

Acquired Hyperostosis Syndrome 1 0 Acute Disease 1 0 Breast Diseases 1 0 ...

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Acquired Hyperostosis Syndrome 1 0 Adenocarcinoma, Sebaceous 1 0 Adenomyoma 1 0 ...

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SAPHO Syndrome. SAPHO Syndrome (Acquired Hyperostosis Syndrome, Pustulosis, Hyperostosis and Osteomyelitis, Synovitis acne ... The term SAPHO Syndrome (Synovitis, Acne, pustulosis, Hyperostosis osteitis) was coined in 1987 by Chamot to describe this ... 8- Charmot AM, Benhamou CL, Khan MF, Baraneck L, Kaplan G, Prost A. (1987). "Acne-Pustulosis-Hyperostosis-osteitis Syndrome. ... Hyperostosis (increase in bone substance) and Osteitis (inflammation of the bone). The cause of Sapho syndrome is unknown, but ...

http://amhe.org/journal/?page_id=1779

Rarer acquired causes include tumors (especially pancoast tumor), hyperostosis, and osteomyelitis Adsons sign and the ... Cervical rib syndrome (compression on brachial plexus and/or subclavian artery caused by bone growth). Costoclavicular syndrome ... Thoracic outlet syndrome (TOS) is a condition in which there is compression of the nerves, arteries, or veins in the passageway ... "Thoracic outlet syndrome". Mount Sinai Hospital, New York. Archived from the original on December 9, 2008. Ambrad-Chalela E, ...

https://en.wikipedia.org/wiki/Thoracic_outlet_syndrome

ACQUIRED HYPEROSTOSIS SYNDROME. SINDROME DE HIPEROSTOSIS ADQUIRIDO. SÍNDROME DE HIPEROSTOSE ADQUIRIDA. ACROSOME REACTION. ... HEPATOPULMONARY SYNDROME. SINDROME HEPATOPULMONAR. SÍNDROME HEPATOPULMONAR. HETERODUPLEX ANALYSIS. ANALISIS HETERODUPLEX. ...

http://decs2018.bvsalud.org/I/decswebpage2i.htm

Acquired Hyperostosis Syndrome. Camurati-Engelmann Syndrome. Cleidocranial Dysplasia. Ellis-Van Creveld Syndrome. ... Hyperostosis, Cortical, Congenital. Hyperostosis Frontalis Interna. Langer-Giedion Syndrome. Osteogenesis Imperfecta. Short Rib ... Hyperostosis, Cortical, Congenital - Hyperostosis Frontalis Interna - Langer-Giedion Syndrome - Osteochondroma - Osteogenesis ... Synonym(s): Dyschondroplasias / Hyperostosis Corticalis Generalisata / Melnick-Needles Syndrome / Multiple Epiphyseal Dysplasia ...

http://www.hon.ch/HONselect/RareDiseases/EN/C05.116.099.708.html

acquired immunity synonyms, acquired immunity pronunciation, acquired immunity translation, English dictionary definition of ... acquired immunity. n. Immunity obtained either from the development of antibodies in response to exposure to an antigen, as ... acquired hyperlipoproteinaemia. *acquired hyperlipoproteinemia. *Acquired hyperostosis syndrome. *acquired ... acquired immunity. Also found in: Thesaurus, Medical, Legal, Encyclopedia, Wikipedia. acquired immunity. n.. Immunity obtained ...

https://www.thefreedictionary.com/acquired+immunity

Acquired Hyperostosis Syndrome. *Fibrous Dysplasia, Monostotic. *Cherubism. *Osteolysis, Essential. *Turner Syndrome. *Female ...

https://wexnermedical.osu.edu/find-a-doctor/rebecca-jackson-md-1315

Acquired Hyperostosis Syndrome/classification , Acquired Hyperostosis Syndrome/diagnosis , Acquired Hyperostosis Syndrome/ ...

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Acquired Hyperostosis Syndrome/diagnosis , Acquired Hyperostosis Syndrome/therapy , Acquired Hyperostosis Syndrome/diagnostic ... Acquired Hyperostosis Syndrome/diagnosis , Acquired Hyperostosis Syndrome/therapy , Acquired Hyperostosis Syndrome , ... Child , Humans , Infant , Male , Acquired Hyperostosis Syndrome/pathology , Acquired Hyperostosis Syndrome/therapy , Chronic ... Female , Humans , Middle Aged , Acquired Hyperostosis Syndrome/diagnosis , Acquired Hyperostosis Syndrome/drug therapy , ...

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Acquired Hyperostosis Syndrome Medicine & Life Sciences * Osteitis Medicine & Life Sciences * Hyperostosis Medicine & Life ... Hyperostosis, and Osteitis to heighten awareness of this entity. Methods: We conducted a Medline search using SAPHO syndrome, ... Hyperostosis, and Osteitis to heighten awareness of this entity. Methods: We conducted a Medline search using SAPHO syndrome, ... Hyperostosis, and Osteitis to heighten awareness of this entity. Methods: We conducted a Medline search using SAPHO syndrome, ...

https://ucdavis.pure.elsevier.com/en/publications/the-sapho-syndrome

Acquired Hyperostosis Syndrome Bone Marrow Buttocks Diagnosis Diagnosis, Differential Edema Female Humans Hyperostosis Magnetic ... Acquired Hyperostosis Syndrome Spiral Cone-Beam Computed Tomography Magnetic Resonance Imaging MeSH Terms expand_less. expand_ ... Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome: A Case of Spine, Pelvis, and Anterior Chest Wall Involvement ... Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is an inflammatory clinical condition with aseptic ...

https://koreamed.org/article/2016JKSR/2017.76.5.358

Acquired Hyperostosis Syndrome (‎1)‎. Acquired Immunodeficiency Syndrome (‎3014)‎. * * Filtrar por: Tema * Página principal de ...

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... anemia Congenital dyserythropoietic anemia Majeed syndrome Pancreatic insufficiency-anemia-hyperostosis syndrome ... Rare anemia Rare hemolytic anemia Rare acquired hemolytic anemia Aplastic anemia Rare constitutional aplastic anemia Rare ... acquired aplastic anemia Rare deficiency anemia Constitutional deficiency anemia Constitutional dyserythropoietic ...

https://www.eurobloodnet.eu/members/experts/44/louis-terriou

53 SAPHO syndrome involves any combination of: Synovitis (inflammation of the joints), Acne, Pustulosis (thick yellow blisters containing pus) often on the palms and soles, Hyperostosis (increase in bone substance) and Osteitis (inflammation of the bones). (malacards.org)
SAPHO Syndrome (Acquired Hyperostosis Syndrome, Pustulosis, Hyperostosis and Osteomyelitis, Synovitis acne pustulosis hyperostosis osteitis) is described as any combination of Synovitis (inflammation of the joints), with acne, Pustulosis (thick yellow blisters containing pus) often in the palms and soles, Hyperostosis (increase in bone substance) and Osteitis (inflammation of the bone). (amhe.org)
The term SAPHO Syndrome (Synovitis, Acne, pustulosis, Hyperostosis osteitis) was coined in 1987 by Chamot to describe this spectrum of inflammatory bone disorder, often but not always associated with dermatologic lesions. (amhe.org)
The two most common entities among generally rare but under-diagnosed autoinflammatory bone disorders are chronic recurrent multifocal osteomyelitis (CRMO) and synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome. (unboundmedicine.com)
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome includes a variety of inflammatory bone disorders associated with dermatologic pathology. (bvsalud.org)
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is an inflammatory clinical condition with aseptic bone lesions and characteristic skin manifestations. (koreamed.org)
Considering SAPHO syndrome in the differential diagnosis, subsequent skin inspection revealed plantar pustulosis. (koreamed.org)

Since, numerous skin conditions with osteoarticular disorders were reported bringing a variation in the name of the pathology as sternoclavicular Hyperostosis, pustulotic arthro-osteitis and acne associated spondyloarthropathy. (amhe.org)
Psoriatic arthritis with axial skeletal involvement and pustular arthritis can be like SAPHO but radiologic signs of osteitis with hyperostosis are not seen in psoriatic arthritis. (amhe.org)
The osteitis associated with SAPHO syndrome usually presents as osteosclerosis, while reports on osteolytic lesions are rare. (bvsalud.org)
Methods: We conducted a Medline search using SAPHO syndrome, chronic recurrent multifocal osteitis/osteomyelitis, and related terms as keywords and extracted further relevant articles from the retrieved references. (elsevier.com)

We have already discussed that the most common site of skeletal involvement in SAPHO Syndrome is the anterior chest followed by the spine with osteosclerosis and hyperostosis. (amhe.org)
Prevalence of diffuse idiopathic skeletal hyperostosis in Budapest, Hungary. (termsreign.ga)
Extra-skeletal involvement can include: uveitis, aortitis (rare), conduction rhythm abnormalities, pulmonary involvement (interstitial and restrictive lung disease), cauda equina syndrome, and amyloidosis. (renalandurologynews.com)

SAPHO Syndrome occurs also in other spondyloarthropathies like psoriatic arthritis, idiopathic ankylosing spondyloarthropathy, spondylopathy associated with inflammatory bowel syndrome. (amhe.org)

PFAPA (periodic fever with aphthous stomatitis, pharyngitis and adenitis) is considered one of the periodic fever syndromes (PFS), which are autoinflammatory diseases characterized by inappropriate, uncontrolled and often spontaneous inflammation in the absence of autoimmunity or infection. (oncologynurseadvisor.com)
Familial cold autoinflammatory syndrome (FCAS). (oncologynurseadvisor.com)
Cold exposure is not necessary as a trigger for clinical exacerbations in Muckle Wells, distinguishing it from Familial Cold Autoinflammatory Syndrome. (clinicaladvisor.com)
Mutations in NLRP3 also cause other cryopyrin-associated periodic syndromes (CAPS): Familial cold autoinflammatory syndrome (FCAS) and some cases of neonatal-onset multisystem inflammatory disease (NOMID). (clinicaladvisor.com)
Periodic fever syndromes (PFS) are a group of rare autoinflammatory diseases characterized by inappropriate, uncontrolled, and often spontaneous signs and symptoms of inflammation. (psychiatryadvisor.com)
We define six categories of autoinflammatory disease: IL-1β activation disorders (inflammasomopathies), NF-κB activation syndromes, protein misfolding disorders, complement regulatory diseases, disturbances in cytokine signaling, and macrophage activation syndromes. (pubmedcentralcanada.ca)

Hyperimmunoglobulinemia D with periodic fever (HIDS) is an inherited periodic fever syndrome (PFS) characterized by unprovoked systemic inflammation in the absence of infectious symptoms or evidence for autoimmunity. (clinicaladvisor.com)
Familial Mediterranean fever (FMF) is the most common inherited periodic fever syndrome and predominantly affects people of Mediterranean origin. (cancertherapyadvisor.com)
Neonatal-onset multisystem inflammatory disease (NOMID) or chronic infantile neurologic cutaneous and articular syndrome (CINCA) is an inherited periodic fever syndrome characterized by inappropriate, uncontrolled and often spontaneous inflammation in the absence of autoimmunity or infection. (oncologynurseadvisor.com)
TNF receptor associated periodic fever syndrome (TRAPS). (oncologynurseadvisor.com)
Muckle-Wells syndrome is an inherited periodic fever syndrome characterized by lifelong recurrent episodes of fever and illness due to seemingly unprovoked inflammation in the absence of autoimmunity or infection. (clinicaladvisor.com)
Are you sure your patient has a hereditary periodic fever syndrome? (cancertherapyadvisor.com)
The following year witnessed the identification of the gene underlying yet another hereditary fever, the hyperimmunoglobulinemia D with periodic fever syndrome (HIDS) ( 5 , 6 ), and the positional cloning of a dominantly inherited gene that causes a curious syndrome of fever, malaise, and hives-like rash upon generalized cold exposure ( 7 ). (pubmedcentralcanada.ca)

n","Chronic pelvic pain\n","Recurrent PID infections\n","Fitz-Hugh-Curtis syndrome - inflammation of the liver surface\n\nSee also the symptoms of Pelvic Inflammatory Disease and Pelv","Juvenile Rheumatoid Arthritis - Systemic JRA is an early onset symptom pattern of JRA occurring in about 20% of JRA cases. (webhealthnetwork.com)

Sapho Syndrome, also known as acquired hyperostosis syndrome , is related to osteomyelitis and synovitis . (malacards.org)
30% of patients with the syndrome can rule out osteomyelitis or discitis. (amhe.org)
Rarer acquired causes include tumors (especially pancoast tumor), hyperostosis, and osteomyelitis Adson's sign and the costoclavicular maneuver lack specificity and sensitivity and should comprise only a small part of the mandatory comprehensive history and physical examination undertaken with a patient suspected of having TOS. (wikipedia.org)

Hypophosphatasia may mimic the bone phenotype of SAPHO syndrome. (nih.gov)

This is a generally benign, selflimited and chronic syndrome, with exacerbations and remissions. (bvsalud.org)
NOMID/ CINCA is the most severe cryoprin-associated periodic syndrome (CAPS) with chronic rash, continuous symptoms and frequent flares not necessarily accompanied by fever. (oncologynurseadvisor.com)
Neonatal onset multisystem inflammatory disorder (NOMID), also known as chronic infantile neurologic cutaneous and articular syndrome (CINCA). (clinicaladvisor.com)
Abdominal examination for tenderness - e.g. tenderness in epigastric area (midline below ribs) may suggest acute or chronic pancreatitis, peptic ulceration of Zollinger-Ellison syndrome, cancer of the pancreas. (rightdiagnosis.com)

This study is designed to evaluate long term efficacy of intravenous bisphosphonates for bone marrow edema in patients with SAPHO syndrome. (clinicaltrials.gov)
The cause of SAPHO syndrome is unknown and treatment is focused on managing symptoms. (malacards.org)
An important gene associated with Sapho Syndrome is LPIN2 (Lipin 2), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Corticotropin-releasing hormone signaling pathway . (malacards.org)
76 SAPHO syndrome includes a variety of inflammatory bone disorders that may be associated with skin. (malacards.org)
There is no specific treatment plan for SAPHO syndrome . (nih.gov)
Recently a curvilinear or semicircular pattern was described in the vertebral body segments helping in differentiating SAPHO Syndrome from Metastatic disease of the spine. (amhe.org)
SAPHO Syndrome cannot be diagnosed hystopathologically. (amhe.org)
Due to their similarities, many authors consider CRMO to be a subtype of SAPHO syndrome. (unboundmedicine.com)
The analysis of the data from 6 children with CRMO (four girls and two boys, age 3.5-14 years) and of 6 children (6 boys, age 13.5-17.5 years) with SAPHO syndrome was performed. (unboundmedicine.com)
The initiating symptom in five patients with SAPHO syndrome were severe acne, while in one patient acne occurred two years after the disease onset. (unboundmedicine.com)
In conclusion, CRMO and SAPHO syndrome have an array of common characteristics, but also a number of differences. (unboundmedicine.com)
We report herein a rare case of SAPHO syndrome associated with bone lesions resembling bone metastasis. (bvsalud.org)
We present a 15-year-old boy with SAPHO syndrome. (bvsalud.org)
Delay in diagnosis of SAPHO syndrome averages 8 months. (bvsalud.org)
SAPHO syndrome is rare, although probably underrecognized because its diagnosis may be challenging because of the wide variability in its musculoskeletal and cutaneous manifestations. (elsevier.com)
Current treatments are empirical and have the objective of providing relief from the at times debilitating pain associated with SAPHO syndrome. (elsevier.com)
This suggests that the pathogenesis of SAPHO syndrome is multifactorial, but this aspect remains poorly explored, although bacteria and immunological dysfunction are hypothesized to play a role. (elsevier.com)
Conclusions: The early recognition, diagnosis, and prompt treatment of SAPHO syndrome can prevent the unnecessary use of long-term antibiotics or invasive procedures, while rapidly alleviating pain in a majority of affected patients. (elsevier.com)
Multilevel bone marrow edema and cortical erosions involving the spine, asymmetric sacroiliitis, and osteosclerosis of the sternoclavicular joint were consistent with a diagnosis of SAPHO syndrome. (koreamed.org)

Until now, only serotypes 4 and 16 have ever been recorded in Cyprus and because of acquired immunity there have been no cases of clinical symptoms in decades. (thefreedictionary.com)
Other conditions that can produce similar symptoms include rotator cuff tear, cervical disc disorders, fibromyalgia, multiple sclerosis, and complex regional pain syndrome. (wikipedia.org)
The symptoms of lower cranial nerve palsy and motor loss skull were recovered, but the symptoms of the foraminal stenosis, such as visual and hyperostosis auditory losses and facial paralysis were not recovered in any way. (bvsalud.org)
Iliotibial Band Syndrome symptoms range from a stinging sensation just above the knee joint (on the outside of the knee or along the entire length of the iliotibial band) to swelling or thickening of the tissue at the point where the band moves over the femur. (bionity.com)

The exostoses in this syndrome appear identical to those of hereditary multiple exostoses (EXOSTOSES, HEREDITARY MULTIPLE). (umassmed.edu)
Hereditary periodic fever (PFS) syndromes are rare defects of innate immunity characterized by inappropriate, uncontrolled and often spontaneous inflammation in the absence of autoimmunity or infection. (cancertherapyadvisor.com)
The concept was proposed ten years ago with the identification of the genes underlying hereditary periodic fever syndromes. (pubmedcentralcanada.ca)

The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. (ctdbase.org)
A Schick test is a skin test for previously acquired immunity to which disease? (thefreedictionary.com)
152 Another download urlaub mit esel disease drug is s number program with an live syndrome following a direct PI( BIII). (theatanzt.eu)
cell line with acquired renal cystic disease: Incidence, detection, and management. (goodbelly.com)
acquired cystic disease of kidney the development of cysts in the formerly noncystic failing kidney in end-stage renal disease . (thefreedictionary.com)
A particular mutation in the COL1A1 gene causes infantile cortical hyperostosis, commonly known as Caffey disease. (medlineplus.gov)
For a better understanding of the problem, we present the systematization of spinal canal stenosis, which reflects the etiology, nature of stenosis, clinical syndromes, severity and course of the disease. (spinalstenosis.doctor)

Results: The SAHPO acronym identifies a syndrome encompassing a variety of osteoarticular disorders that are frequently accompanied by dermatoses characterized by neutrophilic pseudoabscesses, but can also occur in isolation. (elsevier.com)
Heritable and acquired disorders of phosphate metabolism: Etiologies involving FGF23 and current therapeutics. (iu.edu)
Mutations in the COL1A1 gene have been found to cause several forms of Ehlers-Danlos syndrome, a group of disorders that affect the connective tissues supporting the skin, bones, blood vessels, and many other organs and tissues. (medlineplus.gov)

The fever pattern (duration and periodicity) and clinical features are variable between syndromes and patients. (psychiatryadvisor.com)
Many of the randomization process monitoring adherence to clinical assessment is often locally invasive adenoma nelsons syndrome, leading to claudication, bruits, absent neck and arm span. (norfolkspca.com)

Phenotypic and Genotypic Characterization and Treatment of a Cohort With Familial Tumoral Calcinosis/Hyperostosis-Hyperphosphatemia Syndrome. (iu.edu)

Several defective inflammatory/immune responses have been linked to CFTR deficiency including innate and acquired immunity dysregulation, cell membrane lipid abnormalities, and various transcription factor-signaling defects. (thefreedictionary.com)
Rare autosomal recessive syndrome characterized by delayed closing of CRANIAL SUTURES, short stature, ACRO-OSTEOLYSIS of distal phalanges, dental and MAXILLOFACIAL ABNORMALITIES and an increase in bone density that results in frequent BONE FRACTURES. (sickkids.ca)
Iliotibial Band Syndrome is the result of poor training habits, equipment and anatomical abnormalities. (bionity.com)
These changes in collagen increase the risk of blood vessel and organ rupture, and the other abnormalities that can occur with the classical and vascular types of Ehlers-Danlos syndrome. (medlineplus.gov)

Although patients will often mistake the pain of Tietze's Syndrome for a myocardial infarction (heart attack), the syndrome does not progress to cause harm to any organs. (bionity.com)

The latter diagnosis is usually made from the co-occurrence of the other features of the syndrome, particularly the onset of arthritis in relation to an attack of urethritis or dysentery, and that the peripheral joints are almost invariably involved in the arthritis. (renalandurologynews.com)

Periodic fever with aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome. (oncologynurseadvisor.com)
The idea was initially proposed with the identification of ectodomain mutations in the p55 tumor necrosis factor (TNF) receptor in patients with a dominantly inherited syndrome of fever and widespread inflammation (the TNF receptor-associated periodic syndrome, TRAPS) ( 2 ). (pubmedcentralcanada.ca)

We report on the case of a patient with acquired immune deficiency syndrome- and Cryptococcus neoformans meningitis-related mania in which olanzapine was successfully used adjunctively and transiently to antifungal therapy. (termsreign.ga)

If CM-1 exists due to hyperostosis of the cranial bones, the authors were not able to determine a common consensus for the treatment of CM-1 and syringomyelia. (bvsalud.org)

Tietze's syndrome, also known as costochondritis , is a benign inflammation of one or more of the costal cartilages . (bionity.com)

60-90% of patients suffering from this condition will present with anterior chest wall hyperostosis, sclerosis or bone hypertrophy involving especially the sternoclavicular joint. (amhe.org)

citation needed] Only 1% of people with carpal tunnel syndrome have concomitant TOS. (wikipedia.org)

The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome. (ctdbase.org)

This condition is characterized by swelling of soft tissues (muscles, for example), pain, and excessive new bone formation (hyperostosis). (medlineplus.gov)

tiene características radiológicas importantes al momento de establecer el diagnóstico y su origen es multifactorial interviniendo factores genéticos, sobre todo en los genes LPNI2 y NOD2 ubicados en el cromosoma 18, infecciosos e inmunológicos. (bvsalud.org)

Anatomy9

Diseases29

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes2

Anthropology, Education, Sociology and Social Phenomena1

Humanities1

Information Science9

SAPHO syndrome of the temporomandibular joint associated with sudden deafness. (1/31)

SAPHO syndrome or psoriatic arthritis? A familial case study. (2/31)

Diagnostic points and possible origin of osteomyelitis in synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome: a radiographic study of 77 mandibular osteomyelitis cases. (3/31)

SAPHO syndrome treated with pamidronate: an open-label study of 10 patients. (4/31)

Pamidronate in the treatment of childhood SAPHO syndrome. (5/31)

Successful treatment of SAPHO syndrome with zoledronic acid. (6/31)

Isolated thoracic spine lesion: is this the presentation of a SAPHO syndrome? A case report. (7/31)

The usefulness of bone remodelling markers in predicting the efficacy of pamidronate treatment in SAPHO syndrome. (8/31)

Hyperostosis

Acquired Hyperostosis Syndrome

Hyperostosis, Diffuse Idiopathic Skeletal

Hyperostosis Frontalis Interna

Hyperostosis, Sternocostoclavicular

Exostoses

Syndrome

Melorheostosis

Ankylosis

Paleopathology

Papilloma, Inverted

Osteitis

Hyperostosis, Cortical, Congenital

Spinal Osteophytosis

Paranasal Sinuses

Skull

Cervical Vertebrae

Bone Diseases, Developmental

Meningioma

Spinal Diseases

Fibula

Paranasal Sinus Neoplasms

Sternum

Longitudinal Ligaments

Meningeal Neoplasms

Skull Base Neoplasms

Tomography, X-Ray Computed

Nose Neoplasms

Bone and Bones

Down Syndrome

Osteosclerosis

Terminology as Topic

Vocabulary, Controlled

Systematized Nomenclature of Medicine

History, 20th Century

Unified Medical Language System

Subject Headings

Current Procedural Terminology

Osteomyelitis

Recurrence

Chronic Disease

Thoracic Outlet Syndrome

Complex Regional Pain Syndromes

Cervical Rib Syndrome

Ribs

Cervical Rib

Reflex Sympathetic Dystrophy

Encyclopedias as Topic

Peptides

Recombinant Proteins

Molecular Sequence Data

Amino Acid Sequence

Peptide Fragments

Cloning, Molecular

Protein Binding

SAPHO syndrome of the temporomandibular joint associated with sudden deafness. (1/31)

SAPHO syndrome or psoriatic arthritis? A familial case study. (2/31)

Diagnostic points and possible origin of osteomyelitis in synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome: a radiographic study of 77 mandibular osteomyelitis cases. (3/31)

SAPHO syndrome treated with pamidronate: an open-label study of 10 patients. (4/31)

Pamidronate in the treatment of childhood SAPHO syndrome. (5/31)

Successful treatment of SAPHO syndrome with zoledronic acid. (6/31)

Isolated thoracic spine lesion: is this the presentation of a SAPHO syndrome? A case report. (7/31)

The usefulness of bone remodelling markers in predicting the efficacy of pamidronate treatment in SAPHO syndrome. (8/31)

FRI0243 Sapho syndrome in hungary | Annals of the Rheumatic Diseases

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SAPHO Syndrome: Get the Facts on Symptoms and Causes

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How is SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis) differentiated from hidradenitis suppurativa (HS)?

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Keeping it together with an Autoimmune Disease: October 2011

Density of Calcium Release Units Decreased, Diffuse Idiopathic Skeletal Hyperostosis, Diminished Respiratory Excursion: Causes ...

Diffuse idiopathic skeletal hyperostosis