Acoustic Maculae: The sensory areas on the vertical wall of the saccule and in the floor of the utricle. The hair cells in the maculae are innervated by fibers of the VESTIBULAR NERVE.Macula Lutea: An oval area in the retina, 3 to 5 mm in diameter, usually located temporal to the posterior pole of the eye and slightly below the level of the optic disk. It is characterized by the presence of a yellow pigment diffusely permeating the inner layers, contains the fovea centralis in its center, and provides the best phototropic visual acuity. It is devoid of retinal blood vessels, except in its periphery, and receives nourishment from the choriocapillaris of the choroid. (From Cline et al., Dictionary of Visual Science, 4th ed)Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Dictionaries, ChemicalCorpus Luteum: The yellow body derived from the ruptured OVARIAN FOLLICLE after OVULATION. The process of corpus luteum formation, LUTEINIZATION, is regulated by LUTEINIZING HORMONE.Terminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Myosins: A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.Factor VIIa: Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagulation.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Antibody Specificity: The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.Antibodies, Viral: Immunoglobulins produced in response to VIRAL ANTIGENS.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)Cranial Nerves: Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.Cranial Nerve Diseases: Disorders of one or more of the twelve cranial nerves. With the exception of the optic and olfactory nerves, this includes disorders of the brain stem nuclei from which the cranial nerves originate or terminate.Trigeminal Nerve: The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the TRIGEMINAL GANGLION and project to the TRIGEMINAL NUCLEUS of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication.Vestibule, Labyrinth: An oval, bony chamber of the inner ear, part of the bony labyrinth. It is continuous with bony COCHLEA anteriorly, and SEMICIRCULAR CANALS posteriorly. The vestibule contains two communicating sacs (utricle and saccule) of the balancing apparatus. The oval window on its lateral wall is occupied by the base of the STAPES of the MIDDLE EAR.Cranial Nerve Injuries: Dysfunction of one or more cranial nerves causally related to a traumatic injury. Penetrating and nonpenetrating CRANIOCEREBRAL TRAUMA; NECK INJURIES; and trauma to the facial region are conditions associated with cranial nerve injuries.Trigeminal Nerve Diseases: Diseases of the trigeminal nerve or its nuclei, which are located in the pons and medulla. The nerve is composed of three divisions: ophthalmic, maxillary, and mandibular, which provide sensory innervation to structures of the face, sinuses, and portions of the cranial vault. The mandibular nerve also innervates muscles of mastication. Clinical features include loss of facial and intra-oral sensation and weakness of jaw closure. Common conditions affecting the nerve include brain stem ischemia, INFRATENTORIAL NEOPLASMS, and TRIGEMINAL NEURALGIA.Retinal Ganglion Cells: Neurons of the innermost layer of the retina, the internal plexiform layer. They are of variable sizes and shapes, and their axons project via the OPTIC NERVE to the brain. A small subset of these cells act as photoreceptors with projections to the SUPRACHIASMATIC NUCLEUS, the center for regulating CIRCADIAN RHYTHM.Embryology: The study of the development of an organism during the embryonic and fetal stages of life.Retina: The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.Nerve Fibers: Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.Optic Nerve: The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.Photoreceptor Cells, Vertebrate: Specialized PHOTOTRANSDUCTION neurons in the vertebrates, such as the RETINAL ROD CELLS and the RETINAL CONE CELLS. Non-visual photoreceptor neurons have been reported in the deep brain, the PINEAL GLAND and organs of the circadian system.Photoreceptor Cells: Specialized cells that detect and transduce light. They are classified into two types based on their light reception structure, the ciliary photoreceptors and the rhabdomeric photoreceptors with MICROVILLI. Ciliary photoreceptor cells use OPSINS that activate a PHOSPHODIESTERASE phosphodiesterase cascade. Rhabdomeric photoreceptor cells use opsins that activate a PHOSPHOLIPASE C cascade.Canada: The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.Drug Prescriptions: Directions written for the obtaining and use of DRUGS.Product Packaging: Form in which product is processed or wrapped and labeled. PRODUCT LABELING is also available.Prescription Drugs: Drugs that cannot be sold legally without a prescription.Pasteurellosis, Pneumonic: Bovine respiratory disease found in animals that have been shipped or exposed to CATTLE recently transported. The major agent responsible for the disease is MANNHEIMIA HAEMOLYTICA and less commonly, PASTEURELLA MULTOCIDA or HAEMOPHILUS SOMNUS. All three agents are normal inhabitants of the bovine nasal pharyngeal mucosa but not the LUNG. They are considered opportunistic pathogens following STRESS, PHYSIOLOGICAL and/or a viral infection. The resulting bacterial fibrinous BRONCHOPNEUMONIA is often fatal.Prescriptions: Directions written for the obtaining and use of PHARMACEUTICAL PREPARATIONS; MEDICAL DEVICES; corrective LENSES; and a variety of other medical remedies.Ships: Large vessels propelled by power or sail used for transportation on rivers, seas, oceans, or other navigable waters. Boats are smaller vessels propelled by oars, paddles, sail, or power; they may or may not have a deck.Acoustics: The branch of physics that deals with sound and sound waves. In medicine it is often applied in procedures in speech and hearing studies. With regard to the environment, it refers to the characteristics of a room, auditorium, theatre, building, etc. that determines the audibility or fidelity of sounds in it. (From Random House Unabridged Dictionary, 2d ed)Speech Acoustics: The acoustic aspects of speech in terms of frequency, intensity, and time.Speech Production Measurement: Measurement of parameters of the speech product such as vocal tone, loudness, pitch, voice quality, articulation, resonance, phonation, phonetic structure and prosody.Abbreviations as Topic: Shortened forms of written words or phrases used for brevity.Optical Devices: Products or parts of products used to detect, manipulate, or analyze light, such as LENSES, refractors, mirrors, filters, prisms, and OPTICAL FIBERS.Electronics, Medical: The research and development of ELECTRICAL EQUIPMENT AND SUPPLIES for such medical applications as diagnosis, therapy, research, anesthesia control, cardiac control, and surgery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Calibration: Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.Endolymphatic Hydrops: An accumulation of ENDOLYMPH in the inner ear (LABYRINTH) leading to buildup of pressure and distortion of intralabyrinthine structures, such as COCHLEA and SEMICIRCULAR CANALS. It is characterized by SENSORINEURAL HEARING LOSS; TINNITUS; and sometimes VERTIGO.Neuroma, Acoustic: A benign SCHWANNOMA of the eighth cranial nerve (VESTIBULOCOCHLEAR NERVE), mostly arising from the vestibular branch (VESTIBULAR NERVE) during the fifth or sixth decade of life. Clinical manifestations include HEARING LOSS; HEADACHE; VERTIGO; TINNITUS; and FACIAL PAIN. Bilateral acoustic neuromas are associated with NEUROFIBROMATOSIS 2. (From Adams et al., Principles of Neurology, 6th ed, p673)Neuroma: A tumor made up of nerve cells and nerve fibers. (Dorland, 27th ed)Meniere Disease: A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.Ear, Inner: The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions.Hydrops Fetalis: Abnormal accumulation of serous fluid in two or more fetal compartments, such as SKIN; PLEURA; PERICARDIUM; PLACENTA; PERITONEUM; AMNIOTIC FLUID. General fetal EDEMA may be of non-immunologic origin, or of immunologic origin as in the case of ERYTHROBLASTOSIS FETALIS.Aquaporins: A class of porins that allow the passage of WATER and other small molecules across CELL MEMBRANES.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Blogging: Using an INTERNET based personal journal which may consist of reflections, comments, and often hyperlinks.Convolvulaceae: The morning glory family of flowering plants, of the order Solanales, which includes about 50 genera and at least 1,400 species. Leaves are alternate and flowers are funnel-shaped. Most are twining and erect herbs, with a few woody vines, trees, and shrubs.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Gasoline: Volative flammable fuel (liquid hydrocarbons) derived from crude petroleum by processes such as distillation reforming, polymerization, etc.Information Storage and Retrieval: Organized activities related to the storage, location, search, and retrieval of information.Vehicle Emissions: Gases, fumes, vapors, and odors escaping from the cylinders of a gasoline or diesel internal-combustion engine. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Random House Unabridged Dictionary, 2d ed)
Age-related blood flow and capillary changes in the rat utricular macula: a quantitative stereological and microsphere study. (1/15)
Vascular change may contribute to age-related vestibular dysfunction. Previously, we reported a significant age-related decrease in blood flow (BF) and mean capillary diameter (D(cap)) in the rat posterior canal crista. The purpose of this study was to examine an otolith organ, the utricle, for similar changes. Old male Fischer 344 rats (O; 28-31 mos) were anesthetized, and the left cardiac ventricle was transcutaneously injected with radioactive microspheres to determine BF. The temporal bones were removed, fixed, and decalcified. The utricles were dissected free and placed into a gamma counter with the reference samples. The specimens were then plastic embedded and serially sectioned at 1 microm according to the vertical section technique. Microsphere surface counts were made and neuroepithelial BF calculated. A systematic random set of sections was sampled and analyzed using stereological techniques for estimates of D(cap), capillary surface area/unit volume (S(v,cap)), capillary length/ unit volume (L(v,cap)), and volume of utricular neuroepithelium (V(ut)). Using these data, total capillary surface (S(cap)) and total length (L(cap)) were calculated. Statistical comparisons were made with data from our previous study of young animals (Y; 3-6 mos). Results indicate a significant age-related decrease in BF (Y = 0.125 microL/min, O = 0.062 microL/min; P = 0.003), D(cap) (Y = 5.95 micro, O = 4.57 microm; P = 0.0002), S(vcap) (Y = 12.33 mm2/mm3, = 9.87 mm2/mm3, P = 0.016), S(cap) (Y = 0.178 mm2, O = 0.129 mm2; p = 0.01), and V(ut) (Y = 0.014 mm3, O = 0.013 mm3; P = 0.04) with no significant change in L(v,cap) (Y = 655 mm/mm3, O = 686 mm/mm3, P = 0.41) or L(cap) (Y = 9.47 mm, O = 8.96 mm; P = 0.49). These age-related vascular changes are likely to have a significant impact on utricular physiological and thus, dysequilibrium. (+info)Afferent innervation patterns of the saccule in pigeons. (2/15)
The innervation patterns of vestibular saccular afferents were quantitatively investigated in pigeons using biotinylated dextran amine as a neural tracer and three-dimensional computer reconstruction. Type I hair cells were found throughout a large portion of the macula, with the highest density observed in the striola. Type II hair cells were located throughout the macula, with the highest density in the extrastriola. Three classes of afferent innervation patterns were observed, including calyx, dimorph, and bouton units, with 137 afferents being anatomically reconstructed and used for quantitative comparisons. Calyx afferents were located primarily in the striola, innervated a number of type I hair cells, and had small innervation areas. Most calyx afferent terminal fields were oriented parallel to the anterior-posterior axis and the morphological polarization reversal line. Dimorph afferents were located throughout the macula, contained fewer type I hair cells in a calyceal terminal than calyx afferents and had medium sized innervation areas. Bouton afferents were restricted to the extrastriola, with multi-branching fibers and large innervation areas. Most of the dimorph and bouton afferents had innervation fields that were oriented dorso-ventrally but were parallel to the neighboring reversal line. The organizational morphology of the saccule was found to be distinctly different from that of the avian utricle or lagena otolith organs and appears to represent a receptor organ undergoing evolutionary adaptation toward sensing linear motion in terrestrial and aerial species. (+info)Hair bundle heights in the utricle: differences between macular locations and hair cell types. (3/15)
Hair bundle structure is a major determinant of bundle mechanics and thus of a hair cell's ability to encode sound and head movement stimuli. Little quantitative information about bundle structure is available for vestibular organs. Here we characterize hair bundle heights in the utricle of a turtle, Trachemys scripta. We visualized bundles from the side using confocal images of utricular slices. We measured kinocilia and stereocilia heights and array length (distance from tall to short end of bundle), and we calculated a KS ratio (kinocilium height/height of the tallest stereocilia) and bundle slope (height fall-off from tall to short end of bundle). To ensure that our measurements reflect in vivo dimensions as closely as possible, we used fixed but undehydrated utricular slices, and we measured heights in three dimensions by tracing kinocilia and stereocilia through adjacent confocal sections. Bundle heights vary significantly with position on the utricular macula and with hair cell type. Type II hair cells are found throughout the macula. We identified four subgroups that differ in bundle structure: zone 1 (lateral extrastriola), striolar zone 2, striolar zone 3, and zone 4 (medial extrastriola). Type I hair cells are confined to striolar zone 3. They have taller stereocilia, longer arrays, lower KS ratios, and steeper slopes than do neighboring (zone 3) type II bundles. Models and experiments suggest that these location- and type-specific differences in bundle heights will yield parallel variations in bundle mechanics. Our data also raise the possibility that differences in bundle structure and mechanics will help explain location- and type-specific differences in the physiological profiles of utricular afferents, which have been reported in frogs and mammals. (+info)Regeneration of vestibular otolith afferents after ototoxic damage. (4/15)
Regeneration of receptor cells and subsequent functional recovery after damage in the auditory and vestibular systems of many vertebrates is well known. Spontaneous regeneration of mammalian hair cells does not occur. However, recent approaches provide hope for similar restoration of hearing and balance in humans after loss. Newly regenerated hair cells receive afferent terminal contacts, yet nothing is known about how reinnervation progresses or whether regenerated afferents finally develop normal termination fields. We hypothesized that neural regeneration in the vestibular otolith system would recapitulate the topographic phenotype of afferent innervation so characteristic of normal development. We used an ototoxic agent to produce complete vestibular receptor cell loss and epithelial denervation, and then quantitatively examined afferent regeneration at discrete periods up to 1 year in otolith maculas. Here, we report that bouton, dimorph, and calyx afferents all regenerate slowly at different time epochs, through a progressive temporal sequence. Furthermore, our data suggest that both the hair cells and their innervating afferents transdifferentiate from an early form into more advanced forms during regeneration. Finally, we show that regeneration remarkably recapitulates the topographic organization of afferent macular innervation, comparable with that developed through normative morphogenesis. However, we also show that regenerated terminal morphologies were significantly less complex than normal fibers. Whether these structural fiber changes lead to alterations in afferent responsiveness is unknown. If true, adaptive plasticity in the central neural processing of motion information would be necessitated, because it is known that many vestibular-related behaviors fully recover during regeneration. (+info)Zebrafish pax5 regulates development of the utricular macula and vestibular function. (5/15)
The zebrafish otic vesicle initially forms with only two sensory epithelia, the utricular and saccular maculae, which primarily mediate vestibular and auditory function, respectively. Here, we test the role of pax5, which is preferentially expressed in the utricular macula. Morpholino knockdown of pax5 disrupts vestibular function but not hearing. Neurons of the statoacoustic ganglion (SAG) develop normally. Utricular hair cells appear to form normally but a variable number subsequently undergo apoptosis and are extruded from the otic vesicle. Dendrites of the SAG persist in the utricle but become disorganized after hair cell loss. Hair cells in the saccule develop and survive normally. Otic expression of pax5 requires pax2a and fgf3, mutations in which cause vestibular defects, albeit by distinct mechanisms. Thus, pax5 works in conjunction with fgf3 and pax2a to establish and/or maintain the utricular macula and is essential for vestibular function. (+info)Architecture of the mouse utricle: macular organization and hair bundle heights. (6/15)
Hair bundles are critical to mechanotransduction by vestibular hair cells, but quantitative data are lacking on vestibular bundles in mice or other mammals. Here we quantify bundle heights and their variation with macular locus and hair cell type in adult mouse utricular macula. We also determined that macular organization differs from previous reports. The utricle has approximately 3,600 hair cells, half on each side of the line of polarity reversal (LPR). A band of low hair cell density corresponds to a band of calretinin-positive calyces, i.e., the striola. The relation between the LPR and the striola differs from previous reports in two ways. First, the LPR lies lateral to the striola instead of bisecting it. Second, the LPR follows the striolar trajectory anteriorly, but posteriorly it veers from the edge of the striola to reach the posterior margin of the macula. Consequently, more utricular bundles are oriented mediolaterally than previously supposed. Three hair cell classes are distinguished in calretinin-stained material: type II hair cells, type ID hair cells contacting calretinin-negative (dimorphic) afferents, and type IC hair cells contacting calretinin-positive (calyceal) afferents. They differ significantly on most bundle measures. Type II bundles have short stereocilia. Type IC bundles have kinocilia and stereocilia of similar heights, i.e., KS ratios (ratio of kinocilium to stereocilia heights) approximately 1, unlike other receptor classes. In contrast to these class-specific differences, bundles show little regional variation except that KS ratios are lowest in the striola. These low KS ratios suggest that bundle stiffness is greater in the striola than in the extrastriola. (+info)Resting discharge patterns of macular primary afferents in otoconia-deficient mice. (7/15)
(+info)Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere's disease and acoustic neuroma. (8/15)
(+info)... localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere's disease and acoustic neuroma ...
... acoustic maculae MeSH A09.246.631.909.625.125.340 --- hair cells, vestibular MeSH A09.246.631.909.625.125.680 --- otolithic ... macula lutea MeSH A09.371.729.522.436 --- fovea centralis MeSH A09.371.729.690 --- optic disk MeSH A09.371.729.727 --- ...
Within the utricle is a small 2 by 3 mm patch of hair cells called the macula of utricle. The macula of utricle, which lies ... which receives the utricular filaments of the acoustic nerve. The cavity of the utricle communicates behind with the ... The macula consists of three layers. The bottom layer is made of sensory hair cells which are embedded in the bottom of a ... The macula of utricle is a thickening in the wall of the utricle where the epithelium contains vestibular hair cells that ...
... macula cribrosa media) for the passage of filaments of the acoustic nerve to the saccule; and behind this depression is an ... The pyramid and adjoining part of the recessus ellipticus are perforated by a number of holes (macula cribosa superior). The ... which is perforated by a number of holes for the passage of filaments of the acoustic nerve which supply the vestibular end of ...
... or saccular macula), to which are distributed the saccular filaments of the acoustic nerve. The vestibule is a region of the ... The macula of saccule lies in a nearly vertical position. Its function is to detect vertical linear acceleration. It is a 2 mm ... The macula of the utricle is in a horizontal position and detects horizontal acceleration. The coordinated sensory perception ... Each hair cell of the macula contains 40 to 70 stereocilia and one true cilia, called a kinocilium. A gelatinous cover called ...
The other two sensory organs supplied by the vestibular neurons are the maculae of the saccule and utricle. Hair cells of the ... Some older texts call the nerve the acoustic or auditory nerve, but these terms have fallen out of widespread use because they ... It emerges from the pontomedullary junction and exits the inner skull via the internal acoustic meatus (or internal auditory ... maculae in the utricle activate afferent receptors in response to linear acceleration while hair cells of the maculae in the ...
"Macula (Far from Mother Land)" (Takasaki) - 4:46 "Ebony Eyes" (Takasaki, Milky Way) - 5:31 Side two "Wild Boogie Run" (Sasaji ... electric and acoustic guitars, lead vocals on track 4, backing vocals, producer Masanori Sasaji - keyboards and synthesizers, ...
Inner layer of eyeball Retina Ora serrata Optic disc Macula Fovea centralis Optic nerve (see nervous system) Retinal blood ... Tragicus Pyramidal muscle of auricle Antitragicus Transverse muscle of auricle Oblique muscle of auricle External acoustic ... tube Inner ear Bony labyrinth Semicircular canals Cochlea Modiolus Scala vestibuli Helicotrema Scala tympani Internal acoustic ...
The macula sacculi detects vertical acceleration while the macula utriculi is responsible for horizontal acceleration. These ... acoustic hair cells, auditory cells or cells of Corti. The organ of Corti is lined with a single row of inner hair cells and ... They contain the sensory hair cells and otoliths of the macula of utricle and of the saccule, respectively, which respond to ... bony fish contain a sensory cluster called the macula neglecta in the utricle that may have this function. Although fish have ...
... macroscopic macula macular sparing magnocellular nuclei main pulmonary artery major duodenal papilla malleolus malleus ... accessory cuneate nucleus accessory nerve accessory olivary nucleus accommodation reflex acetabulum Achilles tendon acoustic ... interhemispheric fissure intermediate horn cell intermediolateral cell column intermediolateral nucleus internal acoustic ...
Linda went on to release her single acoustic album "Jam" (I am) in 2011 which was written and composed by her. She was the ... In 1978 the famous guitarist & composer Nexhat Macula formed one of the best Albanian rock bands of all time, called "TNT" in ...
In some deep sea fishes like the Antimora, the swim bladder maybe also connected to the Macula of saccule in order for the ... It simulates high-energy sound waves in aquatic far-field, plane-wave acoustic conditions. Siphonophores have a special swim ...
The cochlear nerve (also auditory or acoustic neuron) is one of two parts of the vestibulocochlear nerve, a cranial nerve ...
The ear canal (external acoustic meatus, external auditory meatus, EAM) is a pathway running from the outer ear to the middle ...
Otoliths become detached from the macula (the utricle-based receptor for detecting head position and movement) into the ... Posterior cranial fossa tumours - eg, acoustic neuroma.. *Brainstem lesions.. *Herpes zoster oticus (Ramsay Hunt syndrome). ...
this refers to the inner ear structure, not the macula of the retina. We follow ZFA in including a grouping class for the ... macula. Go to external page http://purl.obolibrary.org/obo/UBERON_0000054 Copy ...
... macula lutea explanation free. What is macula lutea? Meaning of macula lutea medical term. What does macula lutea mean? ... Looking for online definition of macula lutea in the Medical Dictionary? ... 4. macula lutea. adj., adj mac´ular, mac´ulate.. acoustic maculae (ma´culae acus´ticae) the macula sacculi and macula utriculi ... macula lu´tea (macula lu´tea re´tinae) (macula re´tinae) an irregular yellowish depression on the retina, lateral to and ...
... localization and mRNA expression of aquaporins in the macula utriculi of patients with Menieres disease and acoustic neuroma. ... Furthermore, decreased expression of AQP4 in the macula utriculi of patients with Menieres disease has been reported (Ishiyama ...
... macula explanation free. What is macula? Meaning of macula medical term. What does macula mean? ... Looking for online definition of macula in the Medical Dictionary? ... 4. macula lutea. adj., adj mac´ular, mac´ulate.. acoustic maculae (ma´culae acus´ticae) the macula sacculi and macula utriculi ... Related to macula: macula densa, macula adherens. macula. [mak´u-lah] (L.) 1. a stain, spot, or thickening; in anatomy, an area ...
... localization and mRNA expression of aquaporins in the macula utriculi of patients with Menieres disease and acoustic neuroma. ...
Immediately after exposure, damage was observed in the macula statica princeps and on the crista sensory epithelia. Kinocilia ... If the relatively low levels and short exposure applied in this study can induce severe acoustic trauma in cephalopods, the ... The observed impacts on the stato-acoustic organs of the noise-exposed cephalopods suggests the occurrence of an excito-toxic ... to mid-intensity acoustic stimuli have to date not been known to lead to any obvious mechanical damage to the sensory epithelia ...
... or saccular macula), to which are distributed the saccular filaments of the acoustic nerve. The vestibule is a region of the ... The macula of saccule lies in a nearly vertical position. Its function is to detect vertical linear acceleration. It is a 2 mm ... The macula of the utricle is in a horizontal position and detects horizontal acceleration. The coordinated sensory perception ... Each hair cell of the macula contains 40 to 70 stereocilia and one true cilia, called a kinocilium. A gelatinous cover called ...
... localization and mRNA expression of aquaporins in the macula utriculi of patients with Menieres disease and acoustic neuroma ...
The projections emanating from immature vestibular hair cells observed at P0 in the utricular maculae of je/je and +/+ mice ... Auditory brainstem response thresholds were defined as sound levels required for a visible response to acoustic stimuli. The ... B,C) Higher magnification views of the P40 je/je macula and anterior crista shown in panel A. White lines enclose the ... Utricular macula. Differences in stereociliary width and length were shown to special advantage by hair cells in the ...
... located medially between it and the lateral most part of the internal acoustic meatus. It represents clusters of small foramina ... The macula cribrosa is part of the vestibule of the inner ear, ... macula cribrosa media: saccular nerve fibers. * macula cribrosa ... The macula cribrosa is part of the vestibule of the inner ear, located medially between it and the lateral most part of the ... Macula cribrosa. Dr Daniel J Bell ◉ and Assoc Prof Frank Gaillard ◉ ◈ et al. ...
c. it is essentially a test of the macula d. the result is abnormal in patients with ocular albinism e. it can be used to ... b. bilateral acoustic neuroma c. Lischs nodules d. cerebral meningioma e. cavernous haemangioma of the retina answer. 30. a.T ...
A supporting cell, as in the acoustic macula, organ of Corti, olfactory epithelium, taste buds, or testes. ... An epithelial cell possessing stereocilia in the maculae, cristae ampullaris, and organ of Corti. These cells are receptors for ...
Chang S, Fong KE Serous detachment of the macula associated with congenital pit of the optic nerve head. J. Oph. Photog. 19809; ... Chang S, Coleman DJ, Lizzi FL Acoustic measurements of vitreous membrane and retinal thickness in Thijssen JM, Verbeek AM (eds ... Guyer DR, Yannuzzi LA, Chang S, Shields JA, Green WR (editors): Retina-Vitreous-Macula. W.B. Saunders, Philadelphia, 1999. ... Retina-Vitreous-Macula. W.B. Saunders, Philadelphia, 1999. ... Retina-Vitreous-Macula. W.B. Saunders, Philadelphia, 1999. ...
Following acoustic trauma in the zebrafish inner ear, we used microarray analysis to identify genes involved in inner ear ... since GH was significantly up-regulated following acoustic trauma. Microarray analysis, validated with the aid of quantitative ... repair following acoustic exposure. Additionally, we investigated the effect of growth hormone (GH) on cell proliferation in ... teleost fishes are capable of regenerating sensory inner ear hair cells that have been lost following acoustic or ototoxic ...
Retinal burns are most likely to occur in the area of central vision, the macula lutea, having dimensions of approximately 2.0 ... Thermal burn, acoustic damage, or photochemical alteration is possible depending upon the energy absorbed. The biological ... The central region of the macula, termed the fovea centralis, is only about 150 micrometers in diameter and provides detailed ... Lasers operating in pulsed mode present an additional hazard from the possibility of acoustic shock wave generation in the ...
Receptors vestibular system (the macula, or a fixed spot) located utricle and saccule, as well as ampula of three semicircular ... The auditory system includes the outer, middle and inner ear; consist of the cochlea, cochlear nerve, central acoustic nuclei ... Hair cell of Cortis organ of the cochlea are specialized acoustic receptors, which convert electrical impulses into mechanical ... connected to the cochlear nerve in the inner part of internal acoustic passage, go to the cerebellopontine angle, enter ...
Pseudophakic RDs either progress rapidly due to continuous vitreous traction or had already progressed to involving the macula ... explanations for retinal break formation following laser capsulotomy include rupture of the anterior vitreous face or acoustic ... A multiplicity of retinal breaks, poor visibility of breaks, a threatened macula, or macular detachment on presentation ...
Mechanoreceptors located in the acoustic maculae and the semicircular canals that mediate the sense of balance, movement, and ...
The maculae (p 47) consist of flat plates of sensory (hair) and supporting cells. Nerve fibers enter the maculae from beneath ... acoustic neuroma, or sudden hearing loss. Sensorineural hearing loss may be the result of exposure to ototoxic drugs (e.g., ... The end organs for gravity and motion detection consist of five separate sensory organs: the macula of the utricule (pp 47 and ... maculae of the utricule and saccule, cristae of the superior, lateral and posterior semicircular canals). The senses of hearing ...
At the first visit, exudative retinal detachment was observed from the upper retina to the macula of the right eye. Inside the ... such as acoustic shadow, were present (arrow, Fig. 1c). The fundus of the left eye had no abnormal findings. No special ... Further, the retinal structure of the macula had recovered, and right vision had improved to 20/20. ...
The internal acoustic meatus (figs. 5 and 7) presents a rounded border, although its edges are somewhat straightened below and ... It transmits the posterior ampullary nerve to the inferior cribriform macula. The other four are parts of the crescentic ... If the lower edge of the internal acoustic meatus (figs. 5 and 7) be followed forward and inward it passes over the upper edge ... After entering the internal acoustic meatus it traverses the facial foramen in a direction outward and slightly forward and ...
1-E The acoustic neuroma (acoustic schwannoma), which represents 8% of primary intracranial neoplasma, is found in the ... It contains bipolar neurons that innervate the hair cells of the cristae ampullares and the maculae of the utricle and the ... 17-C The acoustic schwannoma, which is found in the cerebellopotine (CP) angle of the posterior cranial fossa, impinges on CNs ... C. Acoustic schwannoma. D. Medial longitudinal fasciculus (MLF) syndrome. E. Multiple selerosis. 18. Is an inner ear disease ...
Scribner took him up, reapply the cherry-red macula. Conditions such as the patient standing of long enough information at 8- ... Tapping over the posterior acoustic shadowing suggestive of the diagnosis. Further assessment has said for ova. Monofilament ...
1895-1901 - normal macula lies in spring, e. Exudate in avf lead iii are not have been worked out of wave. ● abdomen side with ... The history may involve the drainage of cardiology, sporadically, move the acoustic duct and downwards. The sensitivity, 000 ...
UtricleRetinaSaccularNeuromaSemicircular canalsVitreousEpitheliumVestibuleLuteaDiabetic retinopathyUtricularFoveaInternal acoustSacculusSensory epitheliaFishesWhose neuronsAuditoryCochlearRetinal detachmentStimulationStimuliDetectPatientsTraumaTissueAccumulationVisualizationNeurofibromatosisMeasurementResultsCentralHair cellsStructureSuperiorBlue
- Otoliths become detached from the macula (the utricle-based receptor for detecting head position and movement) into the semicircular canals. (patient.info)
- this refers to the inner ear structure, not the macula of the retina. (ebi.ac.uk)
- The macula is the most sensitive part of the retina and is devoid of blood vessels. (thefreedictionary.com)
- At the first visit, exudative retinal detachment was observed from the upper retina to the macula of the right eye. (springer.com)
- The macula edema, macula hole, epiretinal membrane, vitreoretinal composition, RPE and sensorial retina decollements may be examined in-depth and in detail. (koruhastanesi.com)
- b) sclera- 2) Vascular Tunic a) iris- b) ciliary body- c) choroid- 3) Nervous Tunic a) retina- b) retinal pigment epithelium- Contains photoreceptors (rods and cones) Function- **The macula lutea is located in the center of the retina, composed mostly of cones. (unf.edu)
- Rods are not in the macula, but rather in the periphery of the retina. (unf.edu)
- Originally intended primarily for retina specialists to image the macula, it has found its role in other subspecialties that include glaucoma, cornea, and ocular oncology. (biomedsearch.com)
- Vitreoretinal refers to any operation to treat eye problems involving the retina , macula, and vitreous fluid . (conferenceseries.com)
- Vitreoretinal alludes to any activity to treat eye issues including the retina, macula, and vitreous liquid. (ophthalmologyconferences.com)
- According to the widely accepted theory (canalithiasis), otoconia dislodged from the utricular or saccular macula subsequently move into the semicircular canal (SCC) and cause an endolymph displacement that stimulates the cupula of the SCC (4). (thefreedictionary.com)
- This response indicates a transient inhibition of SCM muscle activity after saccular acoustic stimulation. (vestibulology.com)
- The upper part of the vestibular nerve innervates the anterior part of the saccular macula, but the lower part innervates the posterior part. (vestibulology.com)
- Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere's disease and acoustic neuroma. (abcam.com)
- Disease entities of the inner ear include: congenital malformations, loss of sensory cells and nerve fibers (i.e., sensorineural hearing loss), cochlear otosclerosis, Meniere's disease, acoustic neuroma, or sudden hearing loss. (cdc.gov)
- 1-E The acoustic neuroma (acoustic schwannoma), which represents 8% of primary intracranial neoplasma, is found in the cerebellopontine (CP) angle. (brainscape.com)
- Also a lady on the hughs syndrome community who is on plaquenil has just been diagnosed with an acoustic neuroma, the is under the post a serious cautionary tale all about serious side effects to plaquenil. (healthunlocked.com)
- I have never seen a case of acoustic neuroma caused by Plaquenil. (healthunlocked.com)
- Although the pathophysiological process of the disease has not been fully clarified, currently, the widely accepted opinion is that the disease results from the accumulation of otoconia that are detached from the utricular macula in the semicircular canals and thereby sensitizing such canals to gravity (1). (thefreedictionary.com)
- Nerve fibers enter the maculae from beneath the epithelium to innervate the hair cells. (cdc.gov)
- In each of the end organs, the sensory epithelium (macula) is overlain by a massive calcium carbonate biomineralisate, the otolith. (biomedcentral.com)
- The macula cribrosa is part of the vestibule of the inner ear , located medially between it and the lateral most part of the internal acoustic meatus . (radiopaedia.org)
- It is believed that the macula of the lagena takes part in the functioning of the vestibule and that the macula is sensitive to low-frequency vibrations and sounds. (thefreedictionary.com)
- Central high-acuity vision occurs when an image is focused directly on the fovea centralis of the macula lutea. (thefreedictionary.com)
- Her diabetic retinopathy has progressed significantly and there is non-macula retinal oedema present. (centreforeyehealth.com.au)
- BPPV is caused by free otoconia dislodged from the utricular macula that have entered the semicircular canal, where they provoke an inappropriate flow of endolymph whenever the head is rotated in the plane of the affected canal . (thefreedictionary.com)
- The full visual acuity is possible only by the use of the centre of the macula-the fovea. (thefreedictionary.com)
- Section of the facial and acoustic nerves within internal acoustic meatus (the separation between them is not apparent in the section). (wikidoc.org)
- The sacculus of some fishes has only one sensory patch, or macula. (thefreedictionary.com)
- Most fishes, with the exception of those of the order Chimaeriformes, have a special organ of hearing in the sacculus-the lagena with a macula distinct from the original acoustic macula. (thefreedictionary.com)
- Immediately after exposure, damage was observed in the macula statica princeps and on the crista sensory epithelia. (windturbinesyndrome.com)
- While a number of studies have illustrated and analyzed 3D models of inner ears in higher vertebrates, inner ears in fishes have rarely been investigated in 3D, especially with regard to the sensory epithelia of the end organs, the maculae. (biomedcentral.com)
- Unlike mammals, teleost fishes are capable of regenerating sensory inner ear hair cells that have been lost following acoustic or ototoxic trauma. (biomedcentral.com)
- It has been suggested that the 3D curvature of these maculae may also play an important role in hearing abilities in fishes. (biomedcentral.com)
- Future studies investigating functional morphology, phylogenetic potential of inner ear features, or evolution of hearing and inner ear specialization in fishes may benefit from the use of 3D models of inner ears and maculae. (biomedcentral.com)
- The aim of our study therefore was to establish a fast and more reliable method to three-dimensionally reconstruct whole inner ears of fishes with special focus on the reconstruction of the 3D curvature of maculae. (biomedcentral.com)
- The auditory places similarly invigilate to form the inner ear labyrinth, whose neurons form the acoustic ganglion , which enables us to hear. (conferenceseries.com)
- The sound-related places also invigilate to shape the inward ear maze, whose neurons frame the acoustic ganglion, which empowers us to hear. (ophthalmologyconferences.com)
- There are also connections between the principal auditory centers and the cranial and spinal motor nuclei, which subserve acoustic reflexes, but little is known about them. (scribd.com)
- The basilar membrane forms the inferior surface of the cochlear canal, and supports the organ of Corti, responsible for the transduction of acoustic stimuli. (iloencyclopaedia.org)
- We compared the accuracy of axial length (AL) measurement obtained by optical biometry with that obtained by acoustic biometry in eyes with rhegmatogenous retinal detachment (RRD). (dovepress.com)
- Finally, there is topographically patterned input to the superior colliculus and to the cerebellum, the latter receiving some of its input from the pontine nuclei activated by acoustic stimulation. (scribd.com)
- This response is recorded as a change in the activity of the SCM muscle after stimulation of the vestibular system with acoustic signals of approximately 90 dB HL and greater. (vestibulology.com)
- By presenting high-intensity acoustic stimuli to the ear, a set of reflexes are activated. (vestibulology.com)
- The high resolution and in-depth imaging enables to detect and follow the macula diseases in quantitative templates. (koruhastanesi.com)
- Pattern dystrophy of the macula- In a study on 22 confirmed cases of PXE, pattern dystrophy was noted in 27 eyes of 16 patients. (statpearls.com)
- This test is so sensitive that it is positive even in patients with a small acoustic neuromas. (drtbalu.in)
- If the relatively low levels and short exposure applied in this study can induce severe acoustic trauma in cephalopods, the effects of similar noise sources [such as wind turbine arrays] on these species in natural conditions over longer time periods may be considerable. (windturbinesyndrome.com)
- Additionally, we investigated the effect of growth hormone (GH) on cell proliferation in control zebrafish utricles and saccules, since GH was significantly up-regulated following acoustic trauma. (biomedcentral.com)
- Instead, micro burst, acoustic shock waves and photo vaporization to the cellular matrix of the tissue targeted by the laser create micro cavities (perforations) that have a similar effect as one would see on tear-off paper. (lahayesight.com)
- In the process, an acoustic shock wave is generated, which literally tears the tissue apart. (monocrom.com)
- A pathological response consisting of fluid accumulation in the outer plexiform layer of the central macula that results in the formation of visible cystic spaces. (wordpress.com)
- An instrument which employs acoustic radiation at microwave frequencies to allow visualization of the microscopic detail exhibited in elastic properties of an object. (thefreedictionary.com)
- Also known as bilateral acoustic neurofibromatosis. (vivavoceoralmedicineradiology.com)
- e a Tofsims system (IonTOF) with build-in Scanning Probe stage and FIB column for true 3D-composition profiling, a completely automated micro-Hall and sheet resistance measurement tool (Capres) with additional capabilities for measurements on dedicated test structures (prior to full BEOL) and an GHz acoustic Microscope (Tepla) for probing voids in TSVs and stacked dies. (thefreedictionary.com)
- How is Acoustic Measurement System abbreviated? (thefreedictionary.com)
- 2 ]). These reconstructions based on histological serial sections were labor-intensive and results were in part uneven as maculae were prone to distortion or artifacts such as disruption during dehydration or embedding procedures. (biomedcentral.com)
- Thickening of the central macula. (wordpress.com)
- Maculae are characterized by orientation patterns of ciliary bundles of the sensory hair cells, i.e. the morphologically and physiologically polarized ciliary bundles form differently oriented groups on the macula. (biomedcentral.com)
- Further, the retinal structure of the macula had recovered, and right vision had improved to 20/20. (springer.com)
- Autosomal dominant inherited condition characterized by gastrointestinal hamartomatous polyps and tan to dark brown or blue maculae on skin and oral mucosa. (vivavoceoralmedicineradiology.com)