Acinetobacter infections. Medical search

Infections with bacteria of the genus ACINETOBACTER.

A genus of gram-negative bacteria of the family MORAXELLACEAE, found in soil and water and of uncertain pathogenicity.

A species of gram-negative, aerobic bacteria, commonly found in the clinical laboratory, and frequently resistant to common antibiotics.

The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).

A species of gram-negative, aerobic bacteria found in soil and water. Although considered to be normally nonpathogenic, this bacterium is a causative agent of nosocomial infections, particularly in debilitated individuals.

Substances that reduce the growth or reproduction of BACTERIA.

Any infection which a patient contracts in a health-care institution.

A group of beta-lactam antibiotics in which the sulfur atom in the thiazolidine ring of the penicillin molecule is replaced by a carbon atom. THIENAMYCINS are a subgroup of carbapenems which have a sulfur atom as the first constituent of the side chain.

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).

Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.

Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.

Deoxyribonucleic acid that makes up the genetic material of bacteria.

Nonsusceptibility of bacteria to the action of the beta-lactam antibiotics. Mechanisms responsible for beta-lactam resistance may be degradation of antibiotics by BETA-LACTAMASES, failure of antibiotics to penetrate, or low-affinity binding of antibiotics to targets.

The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).

Acinetobacter bacteremia in Hong Kong: prospective study and review. (1/737)

The epidemiological characteristics of 18 patients with acinetobacter bacteremia were analyzed. Patients (mean age, 55.5 years) developed bacteremia after an average of 14.1 days of hospitalization. Fifteen of 16 patients survived bacteremia caused by Acinetobacter baumannii. Cultures of blood from the remaining two patients yielded Acinetobacter lwoffii. Most patients (78%) resided in the general ward, while four patients (22%) were under intensive care. Genotyping by arbitrarily primed polymerase chain reaction analysis and the temporal sequence of isolation were more useful than phenotyping by antimicrobial susceptibility in the determination of the source of bacteremia, and the intravascular catheter was the leading infection source (39% of cases). The possibility of an association of glucose with the pathogenesis of acinetobacter infection was raised. (+info)

Risk factors for nosocomial bloodstream infections due to Acinetobacter baumannii: a case-control study of adult burn patients. (2/737)

Risk factors for Acinetobacter baumannii bloodstream infection (BSI) were studied in patients with severe thermal injury in a burn intensive care unit where A. baumannii was endemic. Of 367 patients hospitalized for severe thermal injury during the study period, 29 patients with nosocomial A. baumannii BSI were identified (attack rate, 7.9%). Cases were compared with 58 matched controls without A. baumannii BSI. The overall mortality rate was 31% among cases and 14% among controls; only two deaths (7%) were considered directly related to A. baumannii BSI. Molecular typing of A. baumannii blood isolates by means of randomly amplified polymorphic DNA analysis and pulsed-field gel electrophoresis revealed the presence of three different strain types. Multivariate analysis showed that female gender (P = .027), total body surface area burn of > 50% (P = .016), prior nosocomial colonization with A. baumannii at a distant site (P = .0002), and use of hydrotherapy (P = .037) were independently associated with the acquisition of A. baumannii BSI in burn patients. These data underscore the need for effective infection control measures for this emerging nosocomial problem. (+info)

Efficacy of sulbactam alone and in combination with ampicillin in nosocomial infections caused by multiresistant Acinetobacter baumannii. (3/737)

From March 1995 to March 1997, sulbactam was prospectively evaluated in patients with non-life-threatening multiresistant Acinetobacter baumannii infections. During this period, 47 patients were treated with sulbactam; of them, five were excluded because they had received < or =48 h of sulbactam therapy. A total of 42 patients, 27 males and 15 females with a mean age of 60+/-15 years, were finally evaluated. Infections were as follows: surgical wound, 19; tracheobronchitis, 12; urinary tract, 7; catheter-related bacteraemia, 2; and pneumonia, 2. Eighteen patients received intravenous sulbactam alone (1 g every 8 h) and 24 patients received intravenous sulbactam/ampicillin (1 g:2 g every 8 h) with no major adverse effects. Of the 42 patients, 39 improved or were cured and showed A. baumannii eradication and one patient had persistence of wound infection after 8 days of sulbactam/ampicillin requiring surgical debridement. Two patients died after 3 days of therapy (one of the deaths was attributable to A. baumannii infection). The in-vitro activity of the sulbactam/ampicillin combination was by virtue of the antimicrobial activity exhibited by sulbactam. Killing curves showed that sulbactam was bacteriostatic; no synergy was observed between ampicillin and sulbactam. Our results indicate that sulbactam may prove effective for non-life-threatening A. baumannii infections. Its role in the treatment of severe infections is unknown. However, the current formulation of sulbactam alone may allow its use at higher doses and provide new potential synergic combinations, particularly for those infections by A. baumannii resistant to imipenem. (+info)

Identification of Acinetobacter baumannii strains with monoclonal antibodies against the O antigens of their lipopolysaccharides. (4/737)

Despite the emergence of Acinetobacter baumannii strains as nosocomial pathogens, simple methods for their phenotypic identification are still unavailable. Murine monoclonal antibodies specific for the O-polysaccharide moiety of the lipopolysaccharide (LPS) of two A. baumannii strains were obtained after immunization with heat-killed bacteria. The monoclonal antibodies were characterized by enzyme immunoassay and by Western and dot blot analyses and were investigated for their potential use for the identification of A. baumannii strains. The antibodies reacted with 46 of the 80 A. baumannii clinical isolates that were investigated, and reactivity was observed with 11 of 14 strains which were isolated during outbreaks in different northwestern European cities; no reactivity was observed with Acinetobacter strains of other genomic species, including the closely related genomic species 1 (Acinetobacter calcoaceticus), 3, and 13 sensu Tjernberg and Ursing, or with other gram-negative bacterial strains. The results show that O-antigen-specific monoclonal antibodies such as the ones described are convenient reagents which can be used to identify Acinetobacter strains in clinical and research laboratories. (+info)

Some immunological properties of lipopolysaccharide from Acinetobacter baumannii. (5/737)

Acinetobacter baumannii, mainly biotype 9, is an important nosocomial opportunist pathogen in Chile and other countries. The biological basis of its virulence and prevalence is still unknown. As lipopolysaccharide (LPS) is often associated with virulence, some biological properties of purified LPS from seven nosocomial isolates, comprising four isolates of A. baumannii biotype 9, two isolates of biotype 8 and one isolate of biotype 1, were investigated. LPS was extracted and purified from each isolate by the hot phenol-water method, and its ability to elicit a mitogenic response and to induce the synthesis of a tumour necrosis factor (TNF-alpha) in mouse spleen cells was determined. Activity was evaluated in vivo by determining the splenic index in comparison with LPS from Salmonella Typhimurium. All seven LPS samples were mitogenic on the basis of cellular proliferation experiments and six induced synthesis of TNF-alpha. Similar results were obtained in in-vivo experiments in which LPS induced spleen cell growth, as shown by determination of the splenic index. These results suggest that the LPS of A. baumannii might contribute to the pathogenic properties of this species. (+info)

Use of a murine O-antigen-specific monoclonal antibody to identify Acinetobacter strains of unnamed genomic species 13 Sensu Tjernberg and Ursing. (6/737)

A monoclonal antibody against the O-antigenic polysaccharide chain of the lipopolysaccharide (LPS) of Acinetobacter strains belonging to the unnamed genomic species 13 Sensu Tjernberg and Ursing (13TU) was obtained after immunization of BALB/c mice with heat-killed bacteria and was characterized by enzyme immunoassay and Western blot analysis, by use of LPS and proteinase K-treated bacterial lysates, analyses in which the antibody was shown to be highly specific for the homologous antigen. In addition, when tested in dot and Western blots, reactivity was observed with 9 of 18 Acinetobacter strains of genomic species 13TU which had been isolated in Germany and Denmark; no reactivity was observed with strains of other genomic species, including the closely related genomic groups 1 (A. calcoaceticus), 2 (A. baumannii), and 3 (unnamed), or with other gram-negative bacteria. The antibody described here represents a convenient reagent for the simple, economical, and accurate differentiation of clinical isolates of genomic species 13TU from other Acinetobacter strains. Although the antibody does not identify all isolates of this genomic group, it is evident that it will be a useful reagent in the development of a serotyping scheme for clinical laboratories. (+info)

Genotypic and phenotypic similarity of multiresistant Acinetobacter baumannii isolates in the Czech Republic. (7/737)

The diversity of 103 clinical isolates of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex obtained between 1991 and 1997 from 17 Czech hospitals was studied by ribotyping, biotyping, plasmid profiling and antibiotic susceptibility testing. According to the EcoRI ribotypes, all but one of these isolates were identified to the DNA group level: 77 isolates were allocated to DNA group 2 (A. baumannii), 14 to DNA group 3, 10 to DNA group 13 sensu Tjernberg and Ursing and one to DNA group 1 (A. calcoaceticus). In total, 50 different EcoRI ribotypes and 10 biotypes were observed. Plasmids were found in 92% of the isolates and a high variability in plasmid profiles was found in isolates of the same DNA group. The combination of typing profiles allowed two predominant groups (termed A and B) to be distinguished among the A. baumannii isolates (37 and eight isolates, respectively) that shared a specific ribotype and were highly similar in other properties. These two groups comprised both sporadic and outbreak isolates and were found in most localities. Group A and B isolates were markedly more resistant to antibiotics than most of the remaining isolates, thus representing 85% of all multiresistant isolates. The features of groups A and B corresponded to those of two epidemic clones identified recently among hospital strains in north-western Europe. (+info)

In vivo efficacies of combinations of beta-lactams, beta-lactamase inhibitors, and rifampin against Acinetobacter baumannii in a mouse pneumonia model. (8/737)

The effects of various regimens containing combinations of beta-lactams, beta-lactam inhibitor(s), and rifampin were assessed in a recently described mouse model of Acinetobacter baumannii pneumonia (M. L. Joly-Guillou, M. Wolff, J. J. Pocidalo, F. Walker, and C. Carbon, Antimicrob. Agents Chemother. 41:345-351, 1997). Two aspects of the therapeutic response were studied: the kinetics of the bactericidal effect (treatment was initiated 3 h after intratracheal inoculation, and bacterial counts were determined over a 24-h period) and survival (treatment was initiated 8 h after inoculation, and the cumulative mortality rate was assessed on day 5). Two clinical strains were used: a cephalosporinase-producing strain (SAN-94040) and a multiresistant strain (RCH-69). For SAN-94040 and RCH-69, MICs and MBCs (milligrams per liter) were as follows: ticarcillin, 32, 64, 256, and >256, respectively; ticarcillin-clavulanate, 32, 64, and 512, and >512, respectively; imipenem, 0.5, 0.5, 8, and 32, respectively; sulbactam, 0.5, 0.5, 8, and 8, respectively; and rifampin, 8, 8, 4, and 4, respectively. Against SAN-94040, four regimens, i.e., imipenem, sulbactam, imipenem-rifampin, and ticarcillin-clavulanate (at a 25/1 ratio)-sulbactam produced a true bactericidal effect (>/=3-log10 reduction of CFU/g of lung). The best survival rate (i.e., 93%) was obtained with the combination of ticarcillin-clavulanate-sulbactam, and regimens containing rifampin provided a survival rate of >/=65%. Against RCH-69, only regimens containing rifampin and the combination of imipenem-sulbactam had a true bactericidal effect. The best survival rates (>/=80%) were obtained with regimens containing rifampin and sulbactam. These results suggest that nonclassical combinations of beta-lactams, beta-lactamase inhibitors, and rifampin should be considered for the treatment of nosocomial pneumonia due to A. baumannii. (+info)

... species are a key source of infection in debilitated patients in the hospital, in particular the species ... Acinetobacter is frequently isolated in nosocomial infections, and is especially prevalent in intensive care units, where both ... Visca P, Seifert H, Towner KJ (December 2011). "Acinetobacter infection--an emerging threat to human health". IUBMB Life. 63 ( ... Trials to implement vaccines to prevent Acinetobacter infections were documented. Reports suggest this bacterium is susceptible ...

https://en.wikipedia.org/wiki/Acinetobacter

2012). "Increase of carbapenem-resistant Acinetobacter baumannii infection in acute care hospitals in Taiwan: Association with ... Aivazova, V; Kainer, F; Friese, K; Mylonas, I (January 2010). "Acinetobacter baumannii infection during pregnancy and ... Acinetobacter can be spread by person-to-person contact or contact with contaminated surfaces. Acinetobacter can enter through ... Parte, A.C. "Acinetobacter". LPSN. Lin, Ming-Feng; Lan, Chung-Yu (2014). "Antimicrobial Resistance in Acinetobacter baumannii: ...

https://en.wikipedia.org/wiki/Acinetobacter_baumannii

... can cause bloodstream infection in neonates. LPSN lpsn.dsmz.de Straininfo of Acinetobacter soli Dongyou Liu ... "Acinetobacter soli as a Cause of Bloodstream Infection in a Neonatal Intensive Care Unit". Journal of Clinical Microbiology. 49 ... Kim, D.; Baik, K. S.; Kim, M. S.; Park, S. C.; Kim, S. S.; Rhee, M. S.; Kwak, Y. S.; Seong, C. N. (2008). "Acinetobacter soli ... Type strain of Acinetobacter soli at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short description, ...

https://en.wikipedia.org/wiki/Acinetobacter_soli

Rathinavelu, S; Zavros, Y; Merchant, JL (June 2003). "Acinetobacter lwoffii infection and gastritis". Microbes and Infection / ... It can cause infections in human hosts, particularly catheter-associated infections in immunocompromised patients. It has also ... Acinetobacter lwoffii, formerly known as Mima polymorpha or Acinetobacter calcoaceticus var. lwoffii, is a non-fermentative ... Type strain of Acinetobacter lwoffii at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short description, ...

https://en.wikipedia.org/wiki/Acinetobacter_lwoffii

"Blood stream infections caused by Acinetobacter ursingii in an obstetrics ward". Infection, Genetics and Evolution. 11 (1): 52- ... "Acinetobacter ursingii sp. nov. and Acinetobacter schindleri sp. nov., isolated from human clinical specimens". International ... and antimicrobial susceptibilities of Acinetobacter ursingii and Acinetobacter schindleri, two frequently misidentified ... Acinetobacter ursingii is a species of potentially pathogenic bacteria. Its type strain is LUH 3792T (= NIPH 137T = LMG 19575T ...

https://en.wikipedia.org/wiki/Acinetobacter_ursingii

"Clinical characteristics of patients with Acinetobacter junii infection". Journal of Microbiology, Immunology, and Infection = ... nov., Acinetobacter haemolyticus sp. nov., Acinetobacter johnsonii sp. nov., and Acinetobacter junii sp. nov. and Emended ... "Acinetobacter junii" at the Encyclopedia of Life Type strain of Acinetobacter junii at BacDive - the Bacterial Diversity ... Bouvet, P. J. M.; Grimont, P. A. D. (1986). "Taxonomy of the Genus Acinetobacter with the Recognition of Acinetobacter ...

https://en.wikipedia.org/wiki/Acinetobacter_junii

LaVergne, Stephanie (March 2018). "Phage Therapy for a Multidrug-Resistant Acinetobacter baumannii Craniectomy Site Infection ... was suffering from a life-threatening multi-drug resistant Acinetobacter baumannii infection, that he had acquired while on ... He is an expert in HIV and hepatitis C (HCV) infection and treatment, and in 2016, was the first physician to treat a patient ... UC San Diego Health, Newsroom (April 2017). "Novel Phage Therapy Saves Patient with Multidrug-Resistant Bacterial Infection". ...

https://en.wikipedia.org/wiki/Robert_T._Schooley

... is a bacterium from the genus of Acinetobacter which has been isolated from human infections. ... Parte, A. C. "Acinetobacter". LPSN. Nemec, A.; Radolfova-Krizova, L.; Maixnerova, M.; Sedo, O. (July 2017). "Acinetobacter ... Type strain of Acinetobacter colistiniresistens at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short ... isolated from human infections and characterized by intrinsic resistance to polymyxins". International Journal of Systematic ...

https://en.wikipedia.org/wiki/Acinetobacter_colistiniresistens

"PheWAS uncovers a pathological role of coagulation Factor X during Acinetobacter baumannii infection". Infection and Immunity. ... Polymorphisms in Factor X have been associated with an increased prevalence in bacterial infections, suggesting a possible role ...

https://en.wikipedia.org/wiki/Factor_X

Use of colistin to treat Acinetobacter baumannii infections has led to the development of resistant bacterial strains. They ... Towner K J (2008). "Molecular Basis of Antibiotic Resistance in Acinetobacter spp.". Acinetobacter Molecular Biology. Caister ... and it has come into recent use for treating multidrug-resistant Acinetobacter infection, although resistant forms have been ... "Colistin and rifampicin in the treatment of nosocomial infections from multiresistant Acinetobacter baumannii". Journal of ...

https://en.wikipedia.org/wiki/Colistin

Infections caused by the non-fermenting gram-negative bacteria Pseudomonas aeruginosa and Acinetobacter baumanni are most ... Rice LB (2006). "Challenges in identifying new antimicrobial agents effective for treating infections with Acinetobacter ... and meropenem are recommended for high-risk community-acquired abdominal infections and for abdominal infections that are ... "Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection ...

https://en.wikipedia.org/wiki/Carbapenem

Iregbu, K. C.; Ogunsola, F. T.; Odugbemi, T. O. (2002). "Infections caused by Acinetobacter species and their susceptibility to ... She was a founding member of the Nigerian Society for Infection control in 1998 and is also a member of the Global Infection ... 1996 Infections caused by Acinetobacter species and their susceptibility to 14 antibiotics in Lagos University Teaching ... She has also been the chairman of the Infection Control Committee of Lagos University Teaching Hospital. Additionally, she is ...

https://en.wikipedia.org/wiki/Folasade_Ogunsola

April 2007). "Control of an outbreak of pandrug-resistant Acinetobacter baumannii colonization and infection in a neonatal ... In the US, the most frequent type of hospital infection is urinary tract infection (36%), followed by surgical site infection ( ... infections of surgery site (14.2%). Infections of the skin and mucous membrane (10.2%), other respiratory infections (6.8%) and ... Nosocomial infections can cause severe pneumonia and infections of the urinary tract, bloodstream and other parts of the body. ...

https://en.wikipedia.org/wiki/Hospital-acquired_infection

Acinetobacter is a gram-negative bacteria that causes pneumonia or bloodstream infections in critically ill patients. Multidrug ... Infections are most frequent in people who have had recent medical and/or antibiotic treatment. C. difficile infections ... Associated with these infections were an estimated 15,000 deaths. The CDC estimates that C. difficile infection costs could ... Centers for Disease Control Prevention (CDC). (2004). "Acinetobacter baumannii infections among patients at military medical ...

https://en.wikipedia.org/wiki/List_of_antibiotic-resistant_bacteria

... -Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection". ... For instance, infection of Pseudomonas aeruginosa by the temperate phage PaP3 changed the expression of 38% (2160/5633) of its ... Therapeutic efficacy of a phage cocktail was evaluated in a mice model with nasal infection of multidrug-resistant (MDR) A. ... Maintaining an appropriate balance in the amounts of each of these proteins produced during viral infection appears to be ...

https://en.wikipedia.org/wiki/Bacteriophage

... critically ill with a completely antibiotic-resistant Acinetobacter baumannii infection following severe pancreatitis. Viruses ... These mimic adenoviral infection, but no resulting propagation of phage nor any cell damage were observed. Natural transcytosis ... PhagoBurn, a Phase 1 and 2 trial of phage therapy against P. aeruginosa wound infection in France and Belgium in 2015-17, was ... Phage therapy has been proposed as a method of treating bacterial infections in the veterinary medical field in response to the ...

https://en.wikipedia.org/wiki/Phage_therapy

"Co-infection and ICU-acquired infection in COIVD-19 ICU patients: a secondary analysis of the UNITE-COVID data set". Critical ... It is often resistant to a wide array of antibiotics but is usually sensitive to co-trimoxazole Acinetobacter are becoming more ... Risk factors for infection with an MDR strain include ventilation for more than five days, recent hospitalization (last 90 days ... As a result of intubation many of the body's defenses against infections are reduced or impaired; this can result in an ability ...

https://en.wikipedia.org/wiki/Ventilator-associated_pneumonia

... therapy after he acquired a life-threatening infection with a 'superbug', Acinetobacter baumannii. Although phage therapy had ... Her early research in Vancouver, Canada identified a major outbreak of HIV infection that occurred among injection drug users ... As a result of the Patterson case, dozens other patients with multidrug resistant bacterial infections have been treated with ... Joel Grimwood was a patient who was ineligible for heart transplantation due to antimicrobial resistant infection. With phage ...

https://en.wikipedia.org/wiki/Steffanie_A._Strathdee

Patterson had a systemic Acinetobacter baumannii infection that manifested while he was on vacation with his wife, Steffanie ... The center currently treats patients with life-threatening multi-drug resistant infections with phage therapy, on a case-by- ... IPATH aims to initiate phase I/II phage therapy clinical trials, focusing on patients with cystic fibrosis and infections ... Phage therapy is the method by which bacteriophages (viruses which infect bacteria) are used to treat bacterial infections or ...

https://en.wikipedia.org/wiki/Center_for_Innovative_Phage_Applications_and_Therapeutics

He is known for his research on healthcare related infections with special emphasis on Acinetobacter, Klebsiella, ESKAPE, Human ...

https://en.wikipedia.org/wiki/Govindan_Rajamohan

... associated with hospital-acquired infections include Acinetobacter baumannii, which cause bacteremia, ... It has also been studied in gram-negative species found in soil such as Pseudomonas stutzeri, Acinetobacter baylyi, and gram- ... That is why some infections with gram-negative bacteria can lead to life-threatening septic shock. The outer membrane protects ... Drugs commonly used to treat gram negative infections include amino, carboxy and ureido penicillins (ampicillin, amoxicillin, ...

https://en.wikipedia.org/wiki/Gram-negative_bacteria

... complicated intra-abdominal infections, complicated urinary tract infections, and nosocomial respiratory tract infections. ... Acinetobacter, and Enterobacter. In addition, some Mycobacteria, including the bacteria that cause tuberculosis, are ... Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more ... In the past, the aminoglycosides have been used in conjunction with beta-lactam antibiotics in streptococcal infections for ...

https://en.wikipedia.org/wiki/Aminoglycoside

They can cause infection in debilitated patients. LPSN lpsn.dsmz.de Straininfo of Acinetobacter pittii Taxonomy Browser Nemec, ... formerly Acinetobacter genomic species 3) and Acinetobacter nosocomialis sp. nov. (formerly Acinetobacter genomic species 13TU ... "Acinetobacter pittii and Acinetobacter nosocomialis among clinical isolates of the Acinetobacter calcoaceticus-baumannii ... characterization of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex with the proposal of Acinetobacter pittii ...

https://en.wikipedia.org/wiki/Acinetobacter_pittii

... is also being investigated for the treatment of infections caused by the Gram-negative bacillus Acinetobacter ... Rifabutin is also used in the treatment of Mycobacterium avium complex disease, a bacterial infection most commonly encountered ... infection. Rifabutin is being tested in clinical trials for treating Crohn's disease as part of the anti-MAP therapy. In a ... "A nutrient-limited screen unmasks rifabutin hyperactivity for extensively drug-resistant Acinetobacter baumannii". Nature ...

https://en.wikipedia.org/wiki/Rifabutin

Cutaneous infections caused by Acinetobacter species (implicated in a number of hospital-acquired infections such as bacteremia ... Woolever, Donald Raj (February 7, 2020). "Skin Infections and Outpatient Burn Management: Fungal and Viral Skin Infections". FP ... Group B streptococcal infection, also known as Group B streptococcal disease or just Group B strep, is the infection caused by ... Common viral skin infections include herpes simplex virus infection, herpes zoster, cutaneous and genital warts, and molluscum ...

https://en.wikipedia.org/wiki/Clobetasone

... research into pathogens infecting combat wounds resulting in the first descriptions of acinetobacter baumannii infection in ... reflecting its focus on tropical infections of interest to the military such as malaria and Dengue fever. In 1947 NAMRU-2 ...

https://en.wikipedia.org/wiki/Naval_Medical_Research_Unit_Two

... airborne acinetobacter infections in a ward were eliminated by the installation of a negative air ioniser-the infection rate ... The frequency of nosocomial infections in British hospitals prompted the National Health Service (NHS) to research the ... McDowell, Natasha (3 January 2003). "Air ionisers wipe out hospital infections". The New Scientist. No. Daily news. Retrieved ...

https://en.wikipedia.org/wiki/Air_ioniser

Acinetobacter infections, a frequent cause of hospital-acquired pneumonia and life-threatening blood or wound infections. ... Vaisman, Daria (2006-05-30). "The Soviet method for attacking infection". Slate Magazine. Retrieved 2022-09-27. Vincent ... Infection and Immunity. In 1989, the journal Science published Fischetti's initial approaches to developing a strep vaccine ... a biopharmaceutical company focusing on the development of novel therapeutics for hard to treat bacterial infections, announced ...

https://en.wikipedia.org/wiki/Vincent_Fischetti

Pseudomonas and Acinetobacter species". Clinical Microbiology and Infection. 20 (9): 831-8. doi:10.1111/1469-0691.12655. PMID ... Antibiotic treatment duration should be based on the infection and other health problems a person may have. For many infections ... reduce the incidence of infection through effective sanitation, hygiene and infection prevention measures. optimize the use of ... Clinical investigation to rule out bacterial infections are often done for patients with pediatric acute respiratory infections ...

https://en.wikipedia.org/wiki/Antimicrobial_resistance

... aureus infection and a disease caused by drug-resistant Acinetobacter spp. A list of uses includes: Amoebic dysentery Anthrax ... Urinary tract infections, rectal infections, and infections of the cervix caused by certain microbes Both minocycline and ... Rogers RL, Perkins J (September 2006). "Skin and soft tissue infections". Prim. Care. 33 (3): 697-710. doi:10.1016/j.pop. ... Minocycline is also used for other skin infections such as methicillin-resistant Staphylococcus aureus. Although minocycline's ...

https://en.wikipedia.org/wiki/Minocycline

In May 2010, a case of infection with E. coli expressing NDM-1 was reported in Coventry in the United Kingdom. The patient was ... In July 2010, a team in New Delhi reported a cluster of three cases of Acinetobacter baumannii bearing blaNDM-1 that were found ... The infection was identified as a carbapenem-resistant Klebsiella pneumoniae strain bearing the novel gene blaNDM-1. The ... in December 2009 in a Swedish national who fell ill with an antibiotic-resistant bacterial infection that he acquired in India ...

https://en.wikipedia.org/wiki/New_Delhi_metallo-beta-lactamase_1

Journal of Infection and Public Health. 9 (3): 362-365. doi:10.1016/j.jiph.2015.11.008. ISSN 1876-0341. PMID 26671497. Baron, ... "Microbiome analysis and confocal microscopy of used kitchen sponges reveal massive colonization by Acinetobacter , Moraxella ... American Journal of Infection Control. 43 (9): 951-955. doi:10.1016/j.ajic.2015.04.196. ISSN 0196-6553. PMID 26050097. ... Surgical Infections. 14 (4): 345-351. doi:10.1089/sur.2012.134. ISSN 1096-2964. PMID 23859684. Suzuki, Asakatsu; Namba, ...

https://en.wikipedia.org/wiki/Microbiomes_of_the_built_environment

Acinetobacter lwoffii, Acinetobacter calcoaceticus, and E.coli. Herpes simplex virus, Adenovirus, Cytomegalovirus[citation ... In this sense, the most likely cause of NSU is a chlamydia infection. However, the term NSU is sometimes distinguished and used ... In women, the signs and symptoms are discharge from vagina, burning or pain when urinating, anal or oral infections, abdominal ... Nongonococcal urethritis (NGU) is an inflammation of the urethra that is not caused by gonorrheal infection. For treatment ...

https://en.wikipedia.org/wiki/Non-gonococcal_urethritis

Sexually transmitted diseases and infections, Bacterial diseases, Chlamydia infections, Infections with a predominantly sexual ... coli Group B streptococcus α-hemolytic streptococcus Coagulase-negative staphylococcus Atopobium vaginae Acinetobacter spp. ... Without treatment, about 10 percent of those with a chlamydial infection and 40 percent of those with a gonorrhea infection ... Even when the PID infection is cured, effects of the infection may be permanent. This makes early identification essential. ...

https://en.wikipedia.org/wiki/Pelvic_inflammatory_disease

Bacteria (Gram-positive and -negative) Acinetobacter spp. Aeromonas hydrophila Bacillus brevis Bacillus cereus Bacillus ... inflammation and bacterial infection in the respiratory tract. Lactoferrin with hypothiocyanite has been granted orphan drug ... "Effects of orally administered bovine lactoferrin and lactoperoxidase on influenza virus infection in mice". J. Med. Microbiol ... weakened respiratory immune system against bacterial infection. Symptoms of cystic fibrosis include an inability to secrete ...

https://en.wikipedia.org/wiki/Hypothiocyanite

They started also working on the HGT capabilities of Acinetobacter baumannii, another human pathogen, known for frequently ... being resistant to a variety of antibiotics, and mostly associated with high infection rates in hospital settings. In order to ...

https://en.wikipedia.org/wiki/Melanie_Blokesch

Zaidi, Sahar; Misba, Lama; Khan, Asad U (2017). "Nano-therapeutics: A revolution in infection control in post antibiotic era". ... "A Plasmid-Borne blaOXA-58 Gene Confers Imipenem Resistance to Acinetobacter baumannii Isolates from a Lebanese Hospital". ... The team led by him collect Escherichia coli and Klebsiella pneumoniae strains from hospital and community-acquired infection ... A Synergistic Approach of Infection Control". PLOS ONE. 9 (3): e91736. Bibcode:2014PLoSO...991736H. doi:10.1371/journal.pone. ...

https://en.wikipedia.org/wiki/Asad_Ullah_Khan

... of infection together with systemic manifestations of infection". These manifestations may include: Tachypnea (fast rate of ... Acinetobacter baumannii, and Pseudomonas aeruginosa". Front Immunol. 6: 595. doi:10.3389/fimmu.2015.00595. PMC 4655328. PMID ... of which are hospital-acquired infections.[citation needed] The process of infection by bacteria or fungi may result in ... The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, ...

https://en.wikipedia.org/wiki/Septic_shock

Phase III studies in complicated intra-abdominal infections (cIAI) and complicated urinary tract infections (cUTI) were ... Acinetobacter baumannii Stenotrophomonas maltophilia Haemophilus influenzae Moraxella catarrhalis Neisseria gonorrhoeae ... "Efficacy and Safety Study of Eravacycline Compared With Meropenem in Complicated Intra-abdominal Infections - Full Text View - ... "Tetraphase Announces Positive Top-Line Results from Phase 3 IGNITE4 Clinical Trial in Complicated Intra-Abdominal Infections ( ...

https://en.wikipedia.org/wiki/Eravacycline

... or splenous infections. B. mallei infection has a fatality rate of 95% if left untreated, and a 50% fatality rate in ... Acinetobacter baumannii, and Pseudomonas aeruginosa". Frontiers in Immunology. 6: 595. doi:10.3389/fimmu.2015.00595. PMC ... Acute infection in horses results in a high fever, loss of fat or muscle, erosion of the surface of the nasal septum, ... Human infection with B. mallei is rare, although it occasionally occurs among laboratory workers dealing with the bacteria or ...

https://en.wikipedia.org/wiki/Burkholderia_mallei

... such as a necrotizing soft tissue infection, an infection causing inflammation of the abdominal cavity lining, an infection of ... Acinetobacter baumannii, the addition of an antibiotic specific to the gram-negative organism is recommended. For methicillin- ... For Legionella infection, addition of macrolide or fluoroquinolone is chosen. If fungal infection is suspected, an echinocandin ... whether the infection is thought to be a hospital or community-acquired infection, and which organ systems are thought to be ...

https://en.wikipedia.org/wiki/Sepsis

Infection and Immunity. 86 (3). doi:10.1128/IAI.00802-17. PMC 5820961. PMID 29311231. Hyams C, Camberlein E, Cohen JM, Bax K, ... "Variation in the Complex Carbohydrate Biosynthesis Loci of Acinetobacter baumannii Genomes". PLOS ONE. 8 (4): e62160. Bibcode: ... Infection and Immunity. 73 (8): 4626-33. doi:10.1128/IAI.73.8.4626-4633.2005. PMC 1201234. PMID 16040975. Schouls L, van der ... Infection and Immunity. 78 (2): 704-15. doi:10.1128/IAI.00881-09. PMC 2812187. PMID 19948837. Rao, Shreesha; Chen, Mei‐Yun; ...

https://en.wikipedia.org/wiki/Bacterial_capsule

... moraxellaceae infections MeSH C01.252.400.560.022 - acinetobacter infections MeSH C01.252.400.610 - mycoplasmatales infections ... bacteroides infections MeSH C01.252.400.126 - bartonellaceae infections MeSH C01.252.400.126.100 - bartonella infections MeSH ... salmonella infections, animal MeSH C01.252.400.310.821.873 - typhoid fever MeSH C01.252.400.310.850 - serratia infections MeSH ... bordetella infections MeSH C01.252.400.143.740 - whooping cough MeSH C01.252.400.155 - borrelia infections MeSH C01.252.400.155 ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C01)

Group A streptococcus such as S. pyogenes, often preceded by varicella infection, may cause severe invasive infections and ... resistant Acinetobacter baumannii". Respirology Case Reports. 8 (8): e00662. doi:10.1002/rcr2.662. PMC 7507560. PMID 32999723. ... In the USA it is observed that NP has increased following influenza owing to the emergence of MRSA strain USA300 infections. a ... In most cases patients with NP have fever, cough and bad breath, and those with more indolent infections have weight loss. ...

https://en.wikipedia.org/wiki/Necrotizing_pneumonia

... for multidrug-resistant Gram-negative bacterial infections such as multidrug-resistant Pseudomonas aeruginosa and Acinetobacter ... It is primarily used for the treatment of infections caused by multi-resistant bacteria including methicillin-resistant ... Matsumoto T (2014). "Arbekacin: another novel agent for treating infections due to methicillin-resistant Staphylococcus aureus ...

https://en.wikipedia.org/wiki/Arbekacin

Infection and Drug Resistance. 12: 965-975. doi:10.2147/idr.s199844. PMC 6519339. PMID 31190901. Hersh, Megan N; Ponder, ... while modulation of the SOS response and endogenous prophage DNA synthesis has been shown to increase Acinetobacter baumannii ... Infection and Drug Resistance. 12: 965-975. doi:10.2147/idr.s199844. PMC 6519339. PMID 31190901. Trevor M. Penning (2011). ... "The Landscape of Phenotypic and Transcriptional Responses to Ciprofloxacin in Acinetobacter baumannii : Acquired Resistance ...

https://en.wikipedia.org/wiki/Mutagenesis

The drug is licensed for the treatment of skin and soft tissue infections as well as intra-abdominal infections. The European ... Acinetobacter baumannii, and E. coli. As a tetracycline derivative antibiotic, its structural modifications has expanded its ... It is approved to treat complicated skin and soft tissue infections (cSSTI), complicated intra-abdominal infections (cIAI), and ... Tigecycline is used to treat different kinds of bacterial infections, including complicated skin and structure infections, ...

https://en.wikipedia.org/wiki/Tigecycline

Kushmaro, A.; Loya, Y.; Fine, M.; Rosenberg, E. (1996). "Bacterial infection causes bleaching of the coral Oculina patagonica ... "The active component of the bioemulsifier alasan from Acinetobacter radioresistens KA53 is an OmpA-like protein". J. Bacteriol ... surface-active polymers from Acinetobacter, and bioremediation. In collaboration with his department colleagues Eliora Z. Ron ...

https://en.wikipedia.org/wiki/Eugene_Rosenberg

... so resistance rates for other infections, such as urinary tract infections may vary. In some settings, laboratory microbiology ... Escherichia coli Klebsiella pneumoniae Pseudomonas aeruginosa Acinetobacter species Streptococcus pneumoniae Staphylococcus ...

https://en.wikipedia.org/wiki/EARS-Net

Infections of this type have been described as a local infection or they can progress into a larger disseminated infection ... "Genetic basis of high level aminoglycoside resistance in Acinetobacter baumannii from Beijing, China". Acta Pharmaceutica ... Other documented infections include osteomyelitis, an infection of the bone that can occur through blood born infection or ... While Corynebacterium infections are not common, when they have been observed it is in individuals with prosthetic devices or ...

https://en.wikipedia.org/wiki/Corynebacterium_striatum

Strategic Advisory Board on Vaccines and Drug-resistant Infections Wellcome Trust. Strategic Advisory Board on Innovation ... such as Acinetobacter baumannii and Pseudomonas aeruginosa strains resistant to Carbapenem. Kieny was one of seven vaccine ... Chair of the Strategic Advisory Board on Vaccines and Drug-resistant Infections Wellcome Trust, Member of the Strategic ...

https://en.wikipedia.org/wiki/Marie-Paule_Kieny

... strains of Acinetobacter baumannii are responsible for an increasing number of opportunistic infections in hospitals.This study ... Phenotypic characterization of Acinetobacter baumannii isolates from intensive care units at a tertiary-care hospital in Egypt ...

https://apps.who.int/iris/browse?authority=Acinetobacter+Infections&type=mesh

... resistant Acinetobacter in an intensive care unit and should be implemented in patients at risk for community-onset infections. ... Infection control practices reduced the rate of multidrug ... ACBA infections were documented in 121 (64%) of the MDR group ... Cite this: Multidrug-Resistant Acinetobacter Infections Remain Prevalent In and Out of Hospital - Medscape - Nov 04, 2009. ... Pneumonia was the most common infection in the MDR group (48 of 121; 39%), whereas urinary tract infection was more common in ...

http://www.medscape.com/viewarticle/711804

https://extranet.who.int/iris/restricted/browse?locale-attribute=en&type=mesh&authority=Acinetobacter+Infections

Acinetobacter baumannii is a well known but relatively uncommon cause of health-care--associated infections. Because the ... Acinetobacter baumannii Infections Among Patients at Military Medical Facilities Treating Injured U.S. Service Members, 2002-- ... Considerations in control and transmission of nosocomial infections due to multi-drug resistant Acinetobacter baumannii. Clin ... Surveillance of nosocomial infections. In: Mayhall CG, ed. Hospital epidemiology and infection control. 3rd ed. Philadelphia, ...

https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5345a1.htm

... secondary infection was defined as infection with a different organism at the same site as the initial Acinetobacter infection. ... had any Acinetobacter infection. The incidence of Acinetobacter infection during the study period represents a significant ... only 2 active-duty soldiers had Acinetobacter infection. A soft tissue infection with Acinetobacter developed in 1 soldier with ... Most Acinetobacter infections reported in the literature reflect nosocomial Acinetobacter, as hospitalized patients are at ...

https://wwwnc.cdc.gov/eid/article/11/8/05-0103

title = "Treatment of Acinetobacter infections",. abstract = "Acinetobacter baumannii remains an important and difficult-to- ... Treatment of Acinetobacter infections. / Fishbain, Joel; Peleg, Anton Yariv.. In: Clinical Infectious Diseases, Vol. 51, No. 1 ... Fishbain, J., & Peleg, A. Y. (2010). Treatment of Acinetobacter infections. Clinical Infectious Diseases, 51(1), 79 - 84. https ... Fishbain, J & Peleg, AY 2010, Treatment of Acinetobacter infections, Clinical Infectious Diseases, vol. 51, no. 1, pp. 79 - ...

https://research.monash.edu/en/publications/treatment-of-acinetobacter-infections

... respiratory and urinary tract infections: Smart 2015 to 2018. ... imipenem/relebactam of pseudomonas aeruginosa and acinetobacter ...

https://www.merck.com/publication/susceptibility-to-imipenem-relebactam-of-pseudomonas-aeruginosa-and-acinetobacter-baumannii-isolates-from-chinese-intra-abdominal-respiratory-and-urinary-tract-infections-smart-2015-to-2018/

Acinetobacter baumannii causes frequently nosocomial infections worldwide. Its ability to survive on dry surfaces facilitates ... Table 1 Changes in rates of multidrug resistant Acinetobacter baumannii infection and colonization: results from the joinpoint ... Acinetobacter baumannii is a frequent etiology of nosocomial infections worldwide, posing a major challenge due to its great ... Nosocomial outbreak of infection with pan-drug-resistant Acinetobacter baumannii in a tertiary care university hospital. Inf ...

https://aricjournal.biomedcentral.com/articles/10.1186/s13756-019-0658-4

https://www.staging.medscape.com/viewarticle/711804

https://wwwnc-origin.cdc.gov/eid/article/11/8/05-0103

Acinetobacter Baumannii Acinetobacter Infections Aged Communicable Diseases, Emerging Cross Infection Drug Resistance, Multiple ... Multidrug-resistant Acinetobacter baumannii, Russia Cite CITE. Title : Multidrug-resistant Acinetobacter baumannii, Russia ... Extreme Drug Resistance in Acinetobacter baumannii Infections in Intensive Care Units, South Korea. ... Title : Extreme Drug Resistance in Acinetobacter baumannii Infections in Intensive Care Units, South Korea Personal Author(s ...

https://stacks.cdc.gov/view/cdc/17350

... antibiotic sensitivity and outcome of therapy of Acinetobacter infection. RESULTS: Acinetobacter infection was not ... 419 patients had a variety of infections and 42 patients had multiple infections. Acinetobacter was isolated in 103 patients ( ... Twenty-four patients succumbed to Acinetobacter infection; in 11 of these patients the organism was resistant to all ... Suri A, Mahapatra AK, Kapil A. Acinetobacter infection in neurosurgical intensive care patients. National Medical Journal of ...

https://imsear.searo.who.int/handle/123456789/118944

Acinetobacter baumannii is a pleomorphic aerobic gram-negative bacillus (similar in appearance to Haemophilus influenzae on ... The most common infection-causing species is A baumannii, followed by Acinetobactercalcoaceticus and Acinetobacterlwoffii. [1] ... When Acinetobacter infections occur, they usually involve organ systems that have a high fluid content (eg, respiratory tract, ... When Acinetobacter causes actual infection, the pathological changes that occur depend on the organ system involved. The ...

http://emedicine.medscape.com/article/236891-overview

Part 3, Chapter 26: Bacterial Infections Skip chapter table of contents and go to main content Hide navigation *. View in ...

http://rooks9.bw.semcs.net/manual/c26-sec-0578

Categories: Acinetobacter Infections Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...

https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Acinetobacter+Infections&parentid=42643&catid=1819

Acinetobacter infection. New England Journal of Medicine, 2008, 358:1271-1281.. *Johnson JR et al. Similarity between human and ... وانخفضت حساسية الراكدة Acinetobacter للإيميبينيم من 99.0% في عام 2004 إلى 32.5% فقط في عام 2008. وظهرت في نفس الفترة مقاومة ... Sensitivity of Acinetobacter spp. to imipenem dropped from 99.0% in 2004 to only 32.5% in 2008. During the same period, almost ... Journal of Infection in Developing Countries, 2009, 3(7):491-497.. *Shibl A. The problem of antibiotic resistance. Arab Health ...

http://www.emro.who.int/emhj-volume-17/issue-6/article3.html

VRSA Infection Pipeline Drugs and Companies, 2021- Phase, Mechanism of Action, Route, Licensing/Collaboration, Pre-clinical and ... Acinetobacter infections - Pipeline Insight, 2022. * Clinical Trials. * 80 Pages *February 2022. * Region: Global ... 4. VRSA Infection Drug Profiles. 4.1 Current Status of VRSA Infection Drug Candidates, 2021. 4.2 VRSA Infection Drugs in ... 3 VRSA Infection Pipeline Snapshot, 2021. 3.1 VRSA Infection Pipeline Drugs- Dominant phase type. 3.2 VRSA Infection pipeline ...

https://www.researchandmarkets.com/reports/5463833/vrsa-infection-pipeline-drugs-and-companies-2021

... targeting Acinetobacter baumannii infections), zoliflodacin (targeting Neisseria gonorrhoeae infections), ETX0282CPDP ( ... About Acinetobacter. Acinetobacter is a Gram-negative, opportunistic human pathogen that predominantly infects critically ill ... and Rybak will discuss the burden and current treatment landscape of Acinetobacter infections. ... to treat infections caused by Acinetobacter baumannii, including carbapenem-resistant strains. Sulbactam-durlobactam has been ...

https://investors.entasistx.com/news-releases/news-release-details/entasis-therapeutics-host-expert-perspectives-webinar

... also known as acinetobacter bacteria includes the home remedy turmeric, essential oils and coconut oil. ... It is called acinetobacter luoffi. I have had a staph infection on my scalp before and had to take antiobiotics for it. I have ... I have a gram negative infection on my face that appears as stubborn acne, please give me herbal or natural advice on what to ... Turns out that this compound is very powerful against infection. Getting or growing garlic would be an excellent idea for ...

https://www.earthclinic.com/cures/gram-negative-infection-acinetobacter-bacteria.html?sortby=loved

MDR Acinetobacter infection compared with patients with susceptible Acinetobacter infections and patients without Acinetobacter ... MDR Acinetobacter infection compared with patients with susceptible Acinetobacter infections and patients without Acinetobacter ... MDR Acinetobacter infection compared with patients with susceptible Acinetobacter infections and patients without Acinetobacter ... MDR Acinetobacter infection compared with patients with susceptible Acinetobacter infections and patients without Acinetobacter ...

https://utsouthwestern.pure.elsevier.com/en/publications/multidrug-resistant-acinetobacter-infection-mortality-rate-and-le

acinetobacter (found in soil and water and responsible for the great majority of infections), ... Scientists believe this may help explain the long-standing problem of why contact lens wearers are more prone to eye infection ... and pseudomonas (widely found in the environment and that can lead to everything from ear infections to more serious issues). ... Americans dont wear contact lenses properly, and it leads to about 1 million eye infections a year] ...

https://www.washingtonpost.com/news/to-your-health/wp/2015/06/01/scientists-detail-all-the-yucky-stuff-in-your-eyes-because-of-your-contact-lenses/

Acinetobacter baumannii, Animals, Community-acquired infections, Environment, Reservoirs. Résumé en anglais. The objective of ... Reservoirs of Acinetobacter baumannii outside the hospital and potential involvement in emerging human community-acquired ... Reservoirs of Acinetobacter baumannii outside the hospital and potential involvement in emerging human community-acquired ... Although the origin of the A. baumannii infections in soldiers injured in Southwestern Asia is difficult to determine, there ...

https://okina.univ-angers.fr/publications/ua11004

Characterized Acinetobacter baumannii-calcoaceticus complex and Pseudomonas aeruginosa Clinical Isolates Causing Infection in ... Cefiderocol In Vitro Activity against Molecularly Characterized Acinetobacter baumannii-calcoaceticus complex and Pseudomonas ... aeruginosa Clinical Isolates Causing Infection in Europe and Adjacent Regions (2020). Lead author: RE Mendes presented at ...

https://www.jmilabs.com/publications/cefiderocol-in-vitro-activity-against-molecularly-characterized-acinetobacter-baumannii-calcoaceticus-complex-and-pseudomonas-aeruginosa-clinical-isolates-causing-infection-in-europe-and-adjacent-regi/

Early-stage Acinetobacter infections product (Phase I). • Acinetobacter infections Pre-clinical and Discovery stage candidates ... Download the Acinetobacter infections Pipeline report to learn more about the emerging Acinetobacter infections therapies at: ... Key companies in the Acinetobacter infections Therapeutics Market:. Some of the Acinetobacter infections Companies working in ... To know more about the Acinetobacter infections pipeline report, click here: Acinetobacter infections Pipeline Insight ...

http://news.delawarenewsreporter.com/story/391770/acinetobacter-infections-pipeline-assessment-fda-ema-and-pmda-approvals-emerging-drugs-clinical-trials-therapeutic-analysis-growth-prospects-and-key-companies-by-delveinsight.html

A study of Acinetobacter infections in a tertiary care hospital in Northeast India ... Acinetobacter is an important opportunistic pathogen and is a common cause of hospital acquired infections. Acinetobacter ... Infection with MDR Acinetobacter species is independently associated with high mortality, emphasizing the need for aggressive ... A study of Acinetobacter infections in a tertiary care hospital in Northeast India. ...

https://www.msjonline.org/index.php/ijrms/article/view/4887

bloodstream infections: A Multicenter retrospective analysis-, INDIAN JOURNAL OF PHARMACOLOGY, cilt.47, ss.95-100, 2015 ... Comparison of colistin monotherapy and non-colistin combinations in the treatment of multi-drug resistant Acinetobacter spp. ... due to multidrug resistant Acinetobacter spp.(MDR-A) . Materials and Methods: Retrospective data of 107 MDR-A BSI cases from 27 ... Comparison of colistin monotherapy and non-colistin combinations in the treatment of multi-drug resistant Acinetobacter spp. ...

https://openaccess.bezmialem.edu.tr/handle/20.500.12645/4375?locale-attribute=tr

These consortiums can colonize a variety of surfaces, such as host tissues, dentures, and catheters, resulting in infections ... Acinetobacter baumannii is well adjusted to hospital environments. Its chronic infections endure predominantly due to its ... The same authors revealed that C. albicans Hyr1 protein can be an immunotherapeutic target for Acinetobacter spp. infection. ... Although the number of anaerobic species involved in infections is lower, compared with the aerobic, and the infections are ...

https://www.mdpi.com/2309-608X/6/1/5

A combination of curcumin and EGCG has an enhanced antimicrobial activity against multidrug resistant Acinetobacter baumannii. ... Diseases : Acinetobacter baumannii infection : CK(36) : AC(26). Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC ... BACKGROUND: Acinetobacter baumannii is an opportunistic human pathogen often associated with life-threatening infections in the ... The combination may have a potential use in medicine as a topical agent to prevent or treat A. baumannii infections. ...

https://greenmedinfo.com/article/combination-curcumin-and-egcg-has-enhanced-antimicrobial-activity-against-mult

They have been used in an effort to combat hospital-acquired infections due to bacteria such as Clostridium difficile, ... Acinetobacter spp., Vancomycin-resistant enterococcus, and methicillin-resistant Staphylococcus aureus, as well as fungi and ... As technology advances to improve health care and reduce hospital-acquired infections, more such hazards may emerge. This case ... Infection-control; Disease-control; Environmental-control-equipment; Control-equipment; Controlled-environment; Environmental- ...

http://www2a.cdc.gov/nioshtic-2/BuildQyr.asp?s1=ozone&f1=%2A&Adv=0&terms=1&PageNo=8&RecNo=73&View=f&

His main research interests are multi-drug resistant Gram-negative bacteria, and infections in immunocompromised patients. (entasistx.com)
Acinetobacter is considered a global threat in the healthcare setting due in part to its ability to acquire multidrug resistance at rates not previously seen in other bacteria. (entasistx.com)
I just was told that I have this bacteria infection on my scalp. (earthclinic.com)
Many strains of that bacteria harmlessly co-exist on our skin but some superstrains have been linked to a growing number of serious antibiotic resistant infections in recent years. (washingtonpost.com)
They have been used in an effort to combat hospital-acquired infections due to bacteria such as Clostridium difficile, Acinetobacter spp. (cdc.gov)
Phagocytosis of bacteria Pseudomonas aeruginosa by neutrophil in patient with bloodstream infection. (scientificamerican.com)
Antibiotic-resistant bacteria may be tougher superbugs than previously thought: Not only are these bacteria harder to treat, they appear to be "fitter" in general, meaning they survive better in the host and cause more deadly infections, a new study suggests. (scientificamerican.com)
In the new study, the researchers examined the effect of genes on antibiotic resistance in Pseudomonas aeruginosa , bacteria that cause lung infections. (scientificamerican.com)
Researchers studying hand contamination and Acinetobacter, a bacteria that can cause healthcare-associated infections, found that healthcare personnel were likely to have the bacteria on their hands after activities as brief as touching a bed rail. (cdc.gov)
Bacteria aren't visible, but busy healthcare providers might forget that clean-looking hands can be contaminated with germs that can cause infections. (cdc.gov)
Infections with bacteria of the genus ACINETOBACTER . (bvsalud.org)
AMPs are produced by bacteria, viruses, plants, and animals, and may be considered as a new class of drugs intended for the prophylaxis and treatment of both systemic and topical infections. (aaem.pl)
In the end it is recommended that effective infection control practices and effective strategies to control antibiotic-resistant bacteria should be applied. (scirp.org)
[ 37 ] Silver formulations may be associated with drug pressure, resulting in infections with resistant bacteria or fungus. (medscape.com)
This phenomenon is similar to the antibody-dependent enhancement of infection by bacteria such as Acinetobacter baumannii and Streptococcus pneumoniae. (bvsalud.org)
Acinetobacter baumannii strains with multiple antimicrobial resistance are primarily known as opportunistic nosocomial bacteria but they may also be regarded as emerging bacterial contaminants of food samples of animal origin. (biomedcentral.com)
The incidence of serious infections caused by multidrug-resistant gram-positive and gram-negative bacteria has been increasing rapidly worldwide despite advances in antibacterial therapy in the last two decades. (erowid.org)
Among multidrug-resistant gram-positive and gram-negative bacteria, methicillin-resistant Staphylococcus aureus, carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii are of great importance, because they have emerged as primary nosocomial pathogens in hospital outbreaks. (erowid.org)
Carbapenem-resistant gram-negative bacteria, namely, carbapenem-resistant Enterobacteriaceae (CRE) (for example, Klebsiella pneumoniae, Escherichia coli), Acinetobacter baumannii (CRAB) and Pseudomonas aeruginosa (CRPsA), are a matter of national and international concern as they are an emerging cause of. (bvsalud.org)
Surgical site infections are caused by bacteria that get in through incisions made during surgery. (bvsalud.org)
In his 1945 Nobel Prize speech, he said if not enough penicillin was given for an infection, bacteria would develop resistance to the antibiotic. (advpharmacy.com)
It turns out that's not true for all infections or for all forms of bacteria. (advpharmacy.com)
Tuberculosis, gonorrhea and malaria are all infections with a high risk of producing mutations resulting in antibiotic-resistant bacteria. (advpharmacy.com)
In this group of patients, strains of non-fermenting gram-negative bacteria - Pseudomonas aeruginosa (in 6 cases) and Acinetobacter baumannii (in 4 cases), which retained sensitivity to carbapenems in 65% of cases, were most often detected. (vestnik-surgery.com)

Three 'superbugs' in particular - Klebsiella, Acinetobacter , and E. coli - were associated with more than half (53 per cent) of the infections. (thehindu.com)

These infections may occur as outbreaks rather than isolated cases of nosocomial pneumonia. (medscape.com)
The 2005 IDSA guidelines for hospital-acquired pneumonia discuss the role of Acinetobacter as a cause of nosocomial pneumonia. (medscape.com)
Acinetobacter is a Gram-negative, opportunistic human pathogen that predominantly infects critically ill patients often resulting in severe pneumonia and bloodstream infections, but can also infect other body sites such as the urinary tract and the skin. (entasistx.com)
They concern community-acquired pneumonia, infections in survivors from natural disasters, and infected war wounds in troops from Iraq and Afghanistan. (univ-angers.fr)
Human infections caused by Acinetobacter species include pneumonia, which is most often related to endotracheal tubes or tracheostomies, endocarditis, meningitis, skin and wound infections, peritonitis in patients receiving peritoneal dialysis, UTI and bacteremia. (biomedcentral.com)
Central line-associated bloodstream infection (CLABSI), ventilator-associated pneumonia (VAP), and cathe- ter-associated urinary tract infection (CAUTI) were assessed in the ICUs of 4 tertiary-care teaching hospitals in Tehran, Islamic Republic of Iran. (who.int)
Central line-associated bloodstream infec- been identified in acute-care settings in low- and middle- tion (CLABSI), ventilator-associated pneumonia (VAP) income countries that are more broadly associated with and catheter-associated urinary tract infection (CAUTI) poverty, such as a lack of basic hygiene, and limited are 3 major device-associated infections (DAIs). (who.int)
The lead author, Marin Llewellyn, said the team reviewed research which showed that for some infections, like those affecting the ear, a longer course is needed, while for others, like pneumonia, a shorter course is just as effective. (advpharmacy.com)

Cite this: Multidrug-Resistant Acinetobacter Infections Remain Prevalent In and Out of Hospital - Medscape - Nov 04, 2009. (medscape.com)
Rekha S, Gokul BN, Beena PM, Prasad SR. Multidrug resistant Acinetobacter isolates from patients admitted at Kolar. (msjonline.org)
Objectives: To compare the efficacy of colistin (COL) monotherapy versus non-COL based combinations in the treatment of bloodstream infections (BSIs) due to multidrug resistant Acinetobacter spp. (bezmialem.edu.tr)
A combination of curcumin and EGCG has an enhanced antimicrobial activity against multidrug resistant Acinetobacter baumannii. (greenmedinfo.com)
In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii. (greenmedinfo.com)
Phage Therapy for a Multidrug-Resistant Acinetobacter baumannii Craniectomy Site Infection. (iteamsonline.org)

War wound infection and osteomyelitis caused by multidrug-resistant (MDR) Acinetobacter species have been prevalent during the 2003-2005 military operations in Iraq. (cdc.gov)
This relative increase of wounded casualties has led to an increased incidence of war wound infection and osteomyelitis, especially caused by multidrug-resistant (MDR) Acinetobacter species. (cdc.gov)
This article reports on severe clinical cases of nosocomial infections that were caused by multidrug-resistant (MDR) isolates of Acinetobacter baumannii and Pseudomonas aeruginosa in an intensive care unit (ICU). (bvsalud.org)

Comparison of colistin monotherapy and non-colistin combinations in the treatment of multi-drug resistant Acinetobacter spp. (bezmialem.edu.tr)
Professor Schembri's outstanding original work in the field of infectious disease and multi-drug resistant pathogens has led to several key advances in the fight to reduce the prevalence and improve outcomes of urinary tract infections. (edu.au)
Over 80 per cent of Acinetobacter infections were multi drug resistant, confirming a pan-resistant, untreatable problem of high mortality in our neonatal [newborn] nurseries. (thehindu.com)

The incidence of bacteremia at military medical facilities caused by Acinetobacter baumannii has also increased ( 2 ). (cdc.gov)

Sulbactam-durlobactam has just completed enrollment of a global Phase 3 registrational clinical trial (ATTACK) to treat infections caused by Acinetobacter baumannii , including carbapenem-resistant strains. (entasistx.com)
SUL-DUR is an intravenous, or IV, investigational drug that is a combination of sulbactam, an IV β-lactam antibiotic, and durlobactam, a novel broad-spectrum IV β-lactamase inhibitor, or BLI, that we are developing for the treatment of infections caused by Acinetobacter baumannii , including carbapenem-resistant strains. (entasistx.com)
The finding "raises a serious concern that drug-resistant strains might be better fit to cause serious, more difficult to treat infections, beyond just the issues raised by the complexity of antibiotic treatment," they said. (scientificamerican.com)
Of equal concern are the evolving antibiotic resistant strains of microorganisms such as Methicillin-resistant Staphhylococcus aureas (MRSA) and Acinetobacter spp, which are making the resulting mortality of a healthcare associated infection greater than ever. (orisonmarketing.com)
We compared the phenotypes of SS9-P10, SS9-P10 cba knockout strains and its complementary strains in vitro and in vivo and found that knocking out the cba gene did not affect the growth characteristics of the strain, but it significantly reduced the ability of SS to form biofilms, adhesion to host cells, phagocytic resistance to macrophages and attenuated virulence in a mouse infection model. (bvsalud.org)

Acinetobacter is an important opportunistic pathogen and is a common cause of hospital acquired infections. (msjonline.org)
Maximum isolates were isolated from urine samples 36 (32.4%) and majority of the isolates were from wards (56.7%) giving a probability of increased hospital acquired infections. (msjonline.org)
As technology advances to improve health care and reduce hospital-acquired infections, more such hazards may emerge. (cdc.gov)
Background: Carbapenemase-producing Enterobacteriaceae (CPE) has been a compelling cause of hospital-acquired infections with a high mortality rate. (researchgate.net)
Dr. Paul's team is working on models to prevent hospital-acquired infections soon after birth, and rapid diagnostics. (thehindu.com)
1* In a 2008 article, the editor of the New England Journal of Medicine, estimated that hospital acquired infections add an average of $15,000 to the cost of care which puts a total cost of infections in the U.S. around $40 billion a year. (orisonmarketing.com)
Hospital-acquired infections (HAI) reflect as a major global safety concern for both patients and health-care professionals. (scirp.org)
The respiratory system and urinary system are the most systems which might be involved by these infections and around 80% - 87% of hospital acquired infections (HCAIs(: "S. aureus", "Enterococcus species" (e.g. (scirp.org)
The increase of both morbidity and mortality related to hospital acquired infections in the intensive care unit (ICU) is a matter of serious problem. (scirp.org)
What are the potential sources of transmitting hospital acquired infections by routine devices in adult ICU in Alrass General Hospital? (scirp.org)

Because the organism has developed substantial antimicrobial resistance, treatment of infections attributed to A. baumannii has become increasingly difficult ( 1 ). (cdc.gov)
The number of these infections and their resistance to multiple antimicrobial agents underscore 1) the importance of infection control during treatment in combat and health-care settings and 2) the need to develop new antimicrobial drugs to treat these infections. (cdc.gov)
Results of 33 A. baumannii isolates from LRMC and 45 isolates from WRAMC indicated widespread resistance to antimicrobial agents commonly used to treat infections with this organism. (cdc.gov)
Despite the drug resistance that infecting organisms demonstrated in this series, a regimen of carefully selected extended antimicrobial-drug therapy appears effective for osteomyelitis caused by MDR Acinetobacter spp. (cdc.gov)
Such infections are challenging to treat because of extensive antimicrobial drug resistance. (cdc.gov)
Acinetobacter baumannii remains an important and difficult-to-treat pathogen whose resistance patterns result in significant challenges for the clinician. (monash.edu)
Acinetobacter baumannii is a frequent etiology of nosocomial infections worldwide, posing a major challenge due to its great ability to develop resistance against antibiotics [ 1 , 2 ]. (biomedcentral.com)
Acinetobacter infections have increased and gained attention because of the organism's prolonged environmental survival and propensity to develop antimicrobial drug resistance. (elsevier.com)
Acinetobacter infections are often extremely difficult to treat because of their widespread resistance to the major groups of antibiotics. (msjonline.org)
Lyytikainen O, Koljalg S, Harma M, Vuopio-Varkila J. Outbreakcaused by two multi-resistant Acinetobacter baumannii clones in a burns unit: emergence of resistance to imipenem. (msjonline.org)
Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania. (msjonline.org)
The emergence of colistin or tigecycline resistance as well as imipenem resistance in Acinetobacter baumannii poses a great therapeutic challenge. (microbiologyresearch.org)
Out of this 1,934 babies (14 per cent) were resistant to drugs and 496 babies (26 per cent) died due to causes attributable to drug resistance and formerly curable infections. (thehindu.com)
Multi drug resistance was the highest with Acinetobacter in 181 cases, a staggering 82 per cent. (thehindu.com)
The limitations in the use of peptides in the treatment of infections, such as susceptibility to proteolysis, and resistance of microorganisms to the peptides, are also discussed. (aaem.pl)
Regarding the Gram-negative bacilli, isolates of Acinetobacter showed 100% resistance to ceftriaxone and ampicillin. (researchsquare.com)
Therefore, a stringent infection vigilance program comprising of routine sampling from the equipments and wards along with antimicrobial resistance surveillance and decontamination efforts must be instituted. (researchsquare.com)

In this study, infection control practices used in patients with hospital-onset MDR ACBA reduced the number of new MDR ACBA infections, and we think that these practices should also be implemented for patients hospitalized with community-onset infections," said Ameet Hingwe, MD, from the Division of Infectious Diseases and Hospital Epidemiology at Henry Ford Hospital in Detroit, Michigan. (medscape.com)
Genomic epidemiology of severe community-onset Acinetobacter baumannii infection. (cdc.gov)

Mortality and morbidity resulting from A baumannii infection relate to the underlying cardiopulmonary immune status of the host rather than the inherent virulence of the organism. (medscape.com)
The morbidity and mortality of Acinetobacter is high in sick patients with multi-organ disease. (delawarenewsreporter.com)
Background: Acinetobacter baumannii infections cause high morbidity and mortality in intensive care unit (ICU) patients. (koreamed.org)
Health care-associated infections (HAI) are one of the most common adverse events in care delivery and a major public health problem with an impact on morbidity, mortality and quality of life. (bvsalud.org)

The predominant predispositions to infection include colonization pressure, exposure to broad-spectrum antibiotics, and disruption of anatomic barriers. (medscape.com)
The acinetobacter bug is being treated with older antibiotics because newer ones do not work. (infiniteunknown.net)
However the overarching goal is to make this an accessible therapy for AMR infections in countries where specialised antibiotics are not available. (iteamsonline.org)
[ 38 ] Furthermore, selective decontamination of the digestive tract with nonabsorbable antibiotics plus cefotaxime significantly increases the risk of MRSA infection. (medscape.com)
For severe infection due to CRE carrying metallo-beta lactamases and/or resistant to all other antibiotics, cefiderocol is conditionally recommended. (medscape.com)
For nonsevere or low-risk infection, use of old antibiotics with in-vitro activity is good clinical practice. (medscape.com)
The discovery of penicillin and other antibiotics in the 20th century radically transformed how we deal with infection. (advpharmacy.com)

In general, Acinetobacter has low virulence, however it is capable of causing infection in immunocompromised and neutropenic patients and it is becoming increasingly drug resistant. (delawarenewsreporter.com)
Recent work in Professor Schembri's group has defined the virulence of this pathogen using advanced genetic, transcriptomic and proteomic methods in conjunction with mouse models of infection. (edu.au)

Infection with MDR Acinetobacter species is independently associated with high mortality, emphasizing the need for aggressive infection control strategies. (msjonline.org)
Healthcare associated infections (HAIs) are the number four cause of death in the United States, exceeding the combined mortality of breast cancer, AIDS and traffic accidents. (orisonmarketing.com)
[ 38 ] however, surgical prophylaxis in patients with burns of more than 40% TBSA appears to reduce the rate of burn wound infections, although it does not affect mortality. (medscape.com)

The current incidence of infection with Acinetobacter should not be surprising. (cdc.gov)
BACKGROUND: This study was performed to analyse the incidence of Acinetobacter infections in neurosurgical patients in the postoperative period. (who.int)
[ 33 ] In nonsurgical patients, systemic antibiotic prophylaxis does not affect the incidence of burn wound infection or sepsis. (medscape.com)

La sensibilité de Staphylococcus aureus à l'oxacilline a diminué significativement, passant de 95,0 % entre 1999 et 2002 à 84,4 % en 2008. (who.int)
Five species were isolated most frequently: Staphylococcus aureus [‎40]‎, Acinetobacter spp. (who.int)
The bacterial isolates were identified as Staphylococcus aureus, Coagulase-negative Staphylococcus (CNS), Acinetobacter sp. (researchsquare.com)

Most of these infections (over 80%) are related to devices' utilization needed for patients' life support as ventilator-associated bloodstream infection (BSI), surgical site infection (SSI), and urinary tract infection (UTI) [5]. (scirp.org)
Trimethoprim-sulfamethoxazole may be considered for nonsevere complicated urinary tract infection (cUTI). (medscape.com)
For more information, please go to Enterobacter Infections , Urinary Tract Infection (UTI) and Cystitis (Bladder Infection) in Females , Urinary Tract Infection in Males , Pseudomonas aeruginosa Infections , and Acinetobacter . (medscape.com)

Acinetobacter baumannii is an opportunistic human pathogen often associated with life-threatening infections in the immunocompromised and the critically ill. (greenmedinfo.com)

This report describes an increasing number of A. baumannii bloodstream infections in patients at military medical facilities in which service members injured in the Iraq/Kuwait region during Operation Iraqi Freedom (OIF) and in Afghanistan during Operation Enduring Freedom (OEF) were treated. (cdc.gov)
In 22 (67%) of these patients, bloodstream infections were detected from blood cultures obtained within 48 hours of ICU admission. (cdc.gov)
Of these, 18 (62%) had bloodstream infections detected from blood cultures obtained within 48 hours of hospital admission after transfer from a combat theater medical or other military medical facility. (cdc.gov)
In addition to LRMC and WRAMC, three other military treatment facilities have identified A. baumannii bloodstream infections in service members injured in Iraq, Kuwait, and Afghanistan: U.S. Navy hospital ship (USNS) Comfort (11 patients), National Naval Medical Center (NNMC), Bethesda, Maryland (eight), and Brooke Army Medical Center (BAMC), San Antonio, Texas (five). (cdc.gov)

Treatment options are limited for this potentially lethal infection, yet most hospitals do not isolate patients with community-acquired MDR ACBA. (medscape.com)
A retrospective, matched cohort investigation was performed at 2 Baltimore hospitals to examine outcomes of patients with MDR Acinetobacter infection compared with patients with susceptible Acinetobacter infections and patients without Acinetobacter infections. (elsevier.com)
Acinetobacter baumannii , which causes infections in people in hospitals, and Vibrio cholera , which causes the diarrheal disease cholera . (scientificamerican.com)
Janet has directed infection prevention programs in the community setting, community-based hospitals, and an academic medical center. (cdc.gov)
There are fears that injured soldiers returning from Iraq and Afghanistan have passed the infection on in civilian hospitals. (infiniteunknown.net)
In October of 2008, Medicaid approved a policy to no longer reimburse hospitals for certain preventable errors (including some types of infections) and Medicare is reserving the right to further expand the list. (orisonmarketing.com)
Risk for infections from Legionella pneumophila for immunocompromised individuals increases greatly when this species is present within the biofilm of the water distribution systems of hospitals or other health facilities. (biomedcentral.com)
Especially when colonizing the water distribution systems of buildings of hospitals or other health facilities, the risk for infections for immunocompromised individuals increases greatly. (biomedcentral.com)

He has also led the use of new treatments to prevent infection by this antibiotic resistant pathogen. (edu.au)
When an infection is identified, antimicrobial therapy should be directed at the pathogen recovered on culture. (medscape.com)
Acinetobacter baumannii is an opportunistic nosocomial pathogen that has increasingly become resistant to carbapenems worldwide. (who.int)

Most Acinetobacter isolates recovered from hospitalized patients, particularly those recovered from respiratory secretions and urine, represent colonization rather than infection. (medscape.com)
Care must be exercised in determining whether the isolate is due to colonization or is truly causing infection. (medscape.com)
Acinetobacter species can be transmitted to patients because of their persistence on environmental surfaces and because of colonization of the hands of healthcare workers. (medscape.com)
The presence of Acinetobacter isolates in respiratory secretions of intubated patients may represent colonization. (medscape.com)
Acinetobacter colonization is particularly common in patients who are intubated and in those who have multiple intravenous lines or monitoring devices, surgical drains, or indwelling urinary catheters. (medscape.com)
Environmental colonization and onward clonal transmission of carbapenem-resistant Acinetobacter baumannii (CRAB) in a medical intensive care unit: the case for environmental hygiene. (infectioncontroltoday.com)
Although colonization of the catheter may be considered a precursor to infection, colonization per se is not considered an infection. (asahq.org)

Patients were followed up to 23 months after completing therapy, and none had recurrent infection with Acinetobacter species. (cdc.gov)
In nonconflict environments, Acinetobacter species are rarely responsible for community-acquired infections. (cdc.gov)
In the hospital setting, Acinetobacter species are an important cause of nosocomial infection, yet these infections were rarely encountered in our facility until we began observing them in soldiers with infected wounds. (cdc.gov)
This case series reviews 1 military medical center's experience with these infections, including species identified, antimicrobial drug-susceptibility patterns, antimicrobial drug therapy, and clinical outcomes. (cdc.gov)
The Acinetobacter has more than 50 species, most of which are nonpathogenic environmental organisms. (medscape.com)
The most common infection-causing species is A baumannii, followed by Acinetobacter calcoaceticus and Acinetobacter lwoffii . (medscape.com)
The study was conducted to determine prevalence and antibiotic susceptibility pattern of Acinetobacter species isolated from various clinical samples. (msjonline.org)
Acinetobacter species isolates were identified, and antibiotic susceptibility test was done following standard operative procedures. (msjonline.org)
Dash M, Padhi S, Patnaik S, Mohanty I, Misra P. Frequency, risk factors and antibiogram of Acinetobacter species isolated from various clinical samples in a tertiary care hospital in Odisha, India. (msjonline.org)
HACEK Infections The HACEK group ( Haemophilus species, Aggregatibacter actinomycetemcomitans , Cardiobacterium hominis , Eikenella corrodens , Kingella kingae ) includes weakly. (merckmanuals.com)

Lessons Learned From the First 10 Consecutive Cases of Intravenous Bacteriophage Therapy to Treat Multidrug-Resistant Bacterial Infections at a Single Center in the United States. (iteamsonline.org)

All of these cases met the criteria for A. baumannii bloodstream infection on the basis of criteria established by CDC's National Nosocomial Infection Surveillance (NNIS) system ( 2 ). (cdc.gov)
CONCLUSION: Acinetobacter is an important nosocomial infection in neurosurgical intensive care patients. (who.int)

noticed an increase in carbapenem-resistant Acinetobacter baumannii (CRAB) infections in the Medical Intensive Care Unit (MICU). (infectioncontroltoday.com)
On the day of PPS, they identified eight CRAB carriers: three who screened positive and five previously known clinical infections. (infectioncontroltoday.com)

Escherichia coli , Yersinia enterocolitica , Acinetobacter spp. (biomedcentral.com)

A study presented here at the Infectious Diseases Society of America 47th Annual Meeting suggests that implementing infection control practices in hospitalized patients at risk for community-onset MDR ACBA could reduce the in-hospital transmission of this infection. (medscape.com)
Overall, the emergence of community-acquired A. baumannii infections could be associated with interactions between animals, environment, and humans that are considered to be potentially involved in the emergence or re-emergence of some infectious diseases. (univ-angers.fr)

Among 111 isolates 109 (98.2%) isolates were Acinetobacter baumanni and 2 (1.8%) were Acinetobacter lwoffii . (msjonline.org)

Acinetobacter is a gram-negative, nonmotile organism that is often found in soil and water and is known to colonize intravenous fluids. (delawarenewsreporter.com)
Infection is them invasion of an organism & body tissues by disease-causing agents, their multiplication, and them reaction of host tissues which is simply illness resulting from an infection. (arraypublishers.com)

This is the first extensive genomic study of carbapenem-resistant A. baumannii in the Philippines, and it underscores the importance of hospital infection control and prevention measures to contain high-risk clones. (who.int)

Surveillance of health care-associated infections (HCAIs) is an integral part of infection control programmes, especially in intensive care units (ICUs). (who.int)

Estimates say two million people a year get antibiotic-resistant infections. (advpharmacy.com)

For infection susceptible to and treated with ceftazidime-avibactam, meropenem-vaborbactam, or cefiderocol, combination therapy is not recommended. (medscape.com)
For severe infection due to CRE susceptible in vitro only to polymyxins, aminoglycosides, tigecycline, or fosfomycin, or if new BLBLIs are unavailable, combination therapy with drugs active in vitro is suggested. (medscape.com)

Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)
This saved the facility a lot of money, and even more importantly, the prevention of dangerous infections. (cdc.gov)
It's a critically important infection prevention measure and applies to every type of patient, in every healthcare setting. (cdc.gov)
is an infection preventionist with the Hospital Infection Prevention Team in the Prevention and Response Branch of CDC's Division of Healthcare Quality Promotion. (cdc.gov)
According to the Centers for Disease Control (CDC) and Prevention in the USA about 1.7 million hospitalized patients annually acquire HAI while being treated for other health issues and that more than 98,000 of these patients die due to the Hospital acquired infection (HAI) [3]. (scirp.org)
Topical antimicrobials for the prevention and treatment of burn wound infection include mafenide acetate, silver sulfadiazine, silver nitrate solution, and silver-impregnated dressings. (medscape.com)
A clinical trial comparing silver sulfadiazine as a cream or as a powdered spray showed the latter formulation achieved higher rates of infection prevention and sterilization. (medscape.com)
Three bundled programmes will be sequentially implemented after a minimum 6-month baseline monitoring period - microbiology and diagnostic stewardship (MDS), infection prevention and control (IPC), and antimicrobial stewardship (ABS). (who.int)
Comparison with global genomes suggested that the establishment of carbapenem-resistant international clone 2 in the Philippines is likely the result of clonal expansion and geographical dissemination, and at least partly explained by inadequate hospital infection control and prevention. (who.int)
Infection prevention in practice. (ufl.edu)
It is intended for public health and infection prevention and control (IPC) professionals, healthcar. (bvsalud.org)

These consortiums can colonize a variety of surfaces, such as host tissues, dentures, and catheters, resulting in infections highly resistant to drugs, when compared with their planktonic counterparts. (mdpi.com)

Outbreak of Acinetobacter baumannii associated with extrinsic contamination of ultrasound gel in a tertiary centre burn unit. (ufl.edu)

Early excision and grafting is the current standard of care and the primary surgical method for reducing infection risk and length of hospital stay and increasing graft take. (medscape.com)

Organisms3

Diseases2

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes3

Acinetobacter bacteremia in Hong Kong: prospective study and review. (1/737)

Risk factors for nosocomial bloodstream infections due to Acinetobacter baumannii: a case-control study of adult burn patients. (2/737)

Efficacy of sulbactam alone and in combination with ampicillin in nosocomial infections caused by multiresistant Acinetobacter baumannii. (3/737)

Identification of Acinetobacter baumannii strains with monoclonal antibodies against the O antigens of their lipopolysaccharides. (4/737)

Some immunological properties of lipopolysaccharide from Acinetobacter baumannii. (5/737)

Use of a murine O-antigen-specific monoclonal antibody to identify Acinetobacter strains of unnamed genomic species 13 Sensu Tjernberg and Ursing. (6/737)

Genotypic and phenotypic similarity of multiresistant Acinetobacter baumannii isolates in the Czech Republic. (7/737)

In vivo efficacies of combinations of beta-lactams, beta-lactamase inhibitors, and rifampin against Acinetobacter baumannii in a mouse pneumonia model. (8/737)

Acinetobacter Infections

Acinetobacter

Acinetobacter baumannii

Drug Resistance, Multiple, Bacterial

Acinetobacter calcoaceticus

Anti-Bacterial Agents

Cross Infection

Carbapenems

Colistin

Microbial Sensitivity Tests

beta-Lactamases

Imipenem

DNA, Bacterial

beta-Lactam Resistance

Drug Resistance, Bacterial

Acinetobacter bacteremia in Hong Kong: prospective study and review. (1/737)

Risk factors for nosocomial bloodstream infections due to Acinetobacter baumannii: a case-control study of adult burn patients. (2/737)

Efficacy of sulbactam alone and in combination with ampicillin in nosocomial infections caused by multiresistant Acinetobacter baumannii. (3/737)

Identification of Acinetobacter baumannii strains with monoclonal antibodies against the O antigens of their lipopolysaccharides. (4/737)

Some immunological properties of lipopolysaccharide from Acinetobacter baumannii. (5/737)

Use of a murine O-antigen-specific monoclonal antibody to identify Acinetobacter strains of unnamed genomic species 13 Sensu Tjernberg and Ursing. (6/737)

Genotypic and phenotypic similarity of multiresistant Acinetobacter baumannii isolates in the Czech Republic. (7/737)

In vivo efficacies of combinations of beta-lactams, beta-lactamase inhibitors, and rifampin against Acinetobacter baumannii in a mouse pneumonia model. (8/737)

Discover Market study on Acinetobacter Infections - Product Pipeline Review 2017 | Medgadget

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