Acinetobacter Infections: Infections with bacteria of the genus ACINETOBACTER.Acinetobacter baumannii: A species of gram-negative, aerobic bacteria, commonly found in the clinical laboratory, and frequently resistant to common antibiotics.Acinetobacter calcoaceticus: A species of gram-negative, aerobic bacteria found in soil and water. Although considered to be normally nonpathogenic, this bacterium is a causative agent of nosocomial infections, particularly in debilitated individuals.Carbapenems: A group of beta-lactam antibiotics in which the sulfur atom in the thiazolidine ring of the penicillin molecule is replaced by a carbon atom. THIENAMYCINS are a subgroup of carbapenems which have a sulfur atom as the first constituent of the side chain.Drug Resistance, Multiple, Bacterial: The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Colistin: Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Cross Infection: Any infection which a patient contracts in a health-care institution.beta-Lactamases: Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.Imipenem: Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.beta-Lactam Resistance: Nonsusceptibility of bacteria to the action of the beta-lactam antibiotics. Mechanisms responsible for beta-lactam resistance may be degradation of antibiotics by BETA-LACTAMASES, failure of antibiotics to penetrate, or low-affinity binding of antibiotics to targets.Drug Resistance, Bacterial: The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Minocycline: A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.Bacterial Proteins: Proteins found in any species of bacterium.Gram-Negative Bacteria: Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.Thienamycins: Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Sulbactam: A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.Alkanes: The generic name for the group of aliphatic hydrocarbons Cn-H2n+2. They are denoted by the suffix -ane. (Grant & Hackh's Chemical Dictionary, 5th ed)Protocatechuate-3,4-Dioxygenase: An enzyme that catalyzes the oxidation of protocatechuate to 3-carboxy-cis-cis-muconate in the presence of molecular oxygen. It contains ferric ion. EC 1.13.11.3.Electrophoresis, Gel, Pulsed-Field: Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.Genes, Bacterial: The functional hereditary units of BACTERIA.Alcaligenes: A genus of gram-negative, aerobic, motile bacteria that occur in water and soil. Some are common inhabitants of the intestinal tract of vertebrates. These bacteria occasionally cause opportunistic infections in humans.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Bacterial Typing Techniques: Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.Gram-Negative Bacterial Infections: Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.DNA Fingerprinting: A technique for identifying individuals of a species that is based on the uniqueness of their DNA sequence. Uniqueness is determined by identifying which combination of allelic variations occur in the individual at a statistically relevant number of different loci. In forensic studies, RESTRICTION FRAGMENT LENGTH POLYMORPHISM of multiple, highly polymorphic VNTR LOCI or MICROSATELLITE REPEAT loci are analyzed. The number of loci used for the profile depends on the ALLELE FREQUENCY in the population.Intensive Care Units: Hospital units providing continuous surveillance and care to acutely ill patients.Moraxella: A genus of gram-negative, aerobic bacteria occurring as rods (subgenus Moraxella) or cocci (subgenus Branhamella). Its organisms are parasitic on the mucous membranes of humans and other warm-blooded animals.Molecular Typing: Using MOLECULAR BIOLOGY techniques, such as DNA SEQUENCE ANALYSIS; PULSED-FIELD GEL ELECTROPHORESIS; and DNA FINGERPRINTING, to identify, classify, and compare organisms and their subtypes.Hospitals, Military: Hospitals which provide care for the military personnel and usually for their dependents.Amikacin: A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.Integrons: DNA elements that include the component genes and insertion site for a site-specific recombination system that enables them to capture mobile gene cassettes.Molecular Epidemiology: The application of molecular biology to the answering of epidemiological questions. The examination of patterns of changes in DNA to implicate particular carcinogens and the use of molecular markers to predict which individuals are at highest risk for a disease are common examples.Transformation, Bacterial: The heritable modification of the properties of a competent bacterium by naked DNA from another source. The uptake of naked DNA is a naturally occuring phenomenon in some bacteria. It is often used as a GENE TRANSFER TECHNIQUE.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Drug Resistance, Microbial: The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Hydroxybenzoates: Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.Hospitals: Institutions with an organized medical staff which provide medical care to patients.beta-Lactams: Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Multilocus Sequence Typing: Direct nucleotide sequencing of gene fragments from multiple housekeeping genes for the purpose of phylogenetic analysis, organism identification, and typing of species, strain, serovar, or other distinguishable phylogenetic level.Disk Diffusion Antimicrobial Tests: A method where a culturing surface inoculated with microbe is exposed to small disks containing known amounts of a chemical agent resulting in a zone of inhibition (usually in millimeters) of growth of the microbe corresponding to the susceptibility of the strain to the agent.Pseudomonas aeruginosa: A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.RNA, Ribosomal, 16S: Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.Catechol 1,2-Dioxygenase: An enzyme that catalyzes the oxidation of catechol to muconic acid with the use of Fe3+ as a cofactor. This enzyme was formerly characterized as EC 1.13.1.1 and EC 1.99.2.2.Parabens: Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents for foods and pharmaceuticals. (From Hawley's Condensed Chemical Dictionary, 11th ed, p872)Genome, Bacterial: The genetic complement of a BACTERIA as represented in its DNA.Biodegradation, Environmental: Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.Pneumonia, Bacterial: Inflammation of the lung parenchyma that is caused by bacterial infections.Monobactams: Monocyclic, bacterially produced or semisynthetic beta-lactam antibiotics. They lack the double ring construction of the traditional beta-lactam antibiotics and can be easily synthesized.Catechols: A group of 1,2-benzenediols that contain the general formula R-C6H5O2.Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Disease Outbreaks: Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.Polymyxins: Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.Enterobacteriaceae: A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.Vanillic Acid: A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).Glucose Dehydrogenases: D-Glucose:1-oxidoreductases. Catalyzes the oxidation of D-glucose to D-glucono-gamma-lactone and reduced acceptor. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.47; EC 1.1.1.118; EC 1.1.1.119 and EC 1.1.99.10.Pneumonia, Ventilator-Associated: Serious INFLAMMATION of the LUNG in patients who required the use of PULMONARY VENTILATOR. It is usually caused by cross bacterial infections in hospitals (NOSOCOMIAL INFECTIONS).Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Aminoglycosides: Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Cluster Analysis: A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.Gram-Positive Bacteria: Bacteria which retain the crystal violet stain when treated by Gram's method.PQQ Cofactor: A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES.Sewage: Refuse liquid or waste matter carried off by sewers.Waxes: A plastic substance deposited by insects or obtained from plants. Waxes are esters of various fatty acids with higher, usually monohydric alcohols. The wax of pharmacy is principally yellow wax (beeswax), the material of which honeycomb is made. It consists chiefly of cerotic acid and myricin and is used in making ointments, cerates, etc. (Dorland, 27th ed)Chromosomes, Bacterial: Structures within the nucleus of bacterial cells consisting of or containing DNA, which carry genetic information essential to the cell.Quinic Acid: An acid which is found in cinchona bark and elsewhere in plants. (From Stedman, 26th ed)DNA Transposable Elements: Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.DNA, Ribosomal: DNA sequences encoding RIBOSOMAL RNA and the segments of DNA separating the individual ribosomal RNA genes, referred to as RIBOSOMAL SPACER DNA.Pseudomonas: A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.Environmental Microbiology: The study of microorganisms living in a variety of environments (air, soil, water, etc.) and their pathogenic relationship to other organisms including man.Polymyxin B: A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.Fuel Oils: Complex petroleum hydrocarbons consisting mainly of residues from crude oil distillation. These liquid products include heating oils, stove oils, and furnace oils and are burned to generate energy.Kanamycin Resistance: Nonsusceptibility of bacteria to the antibiotic KANAMYCIN, which can bind to their 70S ribosomes and cause misreading of messenger RNA.Wound Infection: Invasion of the site of trauma by pathogenic microorganisms.Oxygenases: Oxidases that specifically introduce DIOXYGEN-derived oxygen atoms into a variety of organic molecules.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Amplified Fragment Length Polymorphism Analysis: The detection of RESTRICTION FRAGMENT LENGTH POLYMORPHISMS by selective PCR amplification of restriction fragments derived from genomic DNA followed by electrophoretic analysis of the amplified restriction fragments.Meningitis, Bacterial: Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots.Siderophores: Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994)Biofilms: Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.Bacteriological Techniques: Techniques used in studying bacteria.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Microbial Viability: Ability of a microbe to survive under given conditions. This can also be related to a colony's ability to replicate.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Hospitals, University: Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.Rhizosphere: The immediate physical zone surrounding plant roots that include the plant roots. It is an area of intense and complex biological activity involving plants, microorganisms, other soil organisms, and the soil.Gene Expression Regulation, Bacterial: Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.Gram-Negative Aerobic Bacteria: A large group of aerobic bacteria which show up as pink (negative) when treated by the gram-staining method. This is because the cell walls of gram-negative bacteria are low in peptidoglycan and thus have low affinity for violet stain and high affinity for the pink dye safranine.Mandelic Acids: Analogs or derivatives of mandelic acid (alpha-hydroxybenzeneacetic acid).Pseudomonas Infections: Infections with bacteria of the genus PSEUDOMONAS.4-Hydroxybenzoate-3-Monooxygenase: A flavoprotein that catalyzes the synthesis of protocatechuic acid from 4-hydroxybenzoate in the presence of molecular oxygen. EC 1.14.13.2.Equipment and Supplies, Hospital: Any materials used in providing care specifically in the hospital.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Polyphosphates: Linear polymers in which orthophosphate residues are linked with energy-rich phosphoanhydride bonds. They are found in plants, animals, and microorganisms.Drug Resistance, Multiple: Simultaneous resistance to several structurally and functionally distinct drugs.Colony Count, Microbial: Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.Phosphotransferases (Phosphate Group Acceptor): A group of enzymes that catalyzes the transfer of a phosphate group onto a phosphate group acceptor. EC 2.7.4.Glucose 1-Dehydrogenase: A glucose dehydrogenase that catalyzes the oxidation of beta-D-glucose to form D-glucono-1,5-lactone, using NAD as well as NADP as a coenzyme.CephalosporinaseIraqPediculus: Lice of the genus Pediculus, family Pediculidae. Pediculus humanus corporus is the human body louse and Pediculus humanus capitis is the human head louse.Tetracyclines: Closely congeneric derivatives of the polycyclic naphthacenecarboxamide. (Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1117)Ceftazidime: Semisynthetic, broad-spectrum antibacterial derived from CEPHALORIDINE and used especially for Pseudomonas and other gram-negative infections in debilitated patients.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Infection Control: Programs of disease surveillance, generally within health care facilities, designed to investigate, prevent, and control the spread of infections and their causative microorganisms.Water Microbiology: The presence of bacteria, viruses, and fungi in water. This term is not restricted to pathogenic organisms.HydrocarbonsTertiary Care Centers: A medical facility which provides a high degree of subspecialty expertise for patients from centers where they received SECONDARY CARE.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Klebsiella pneumoniae: Gram-negative, non-motile, capsulated, gas-producing rods found widely in nature and associated with urinary and respiratory infections in humans.Cilastatin: A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.Benzoates: Derivatives of BENZOIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure.Soil Microbiology: The presence of bacteria, viruses, and fungi in the soil. This term is not restricted to pathogenic organisms.Alcohol Oxidoreductases: A subclass of enzymes which includes all dehydrogenases acting on primary and secondary alcohols as well as hemiacetals. They are further classified according to the acceptor which can be NAD+ or NADP+ (subclass 1.1.1), cytochrome (1.1.2), oxygen (1.1.3), quinone (1.1.5), or another acceptor (1.1.99).Benzaldehyde Dehydrogenase (NADP+)Conjugation, Genetic: A parasexual process in BACTERIA; ALGAE; FUNGI; and ciliate EUKARYOTA for achieving exchange of chromosome material during fusion of two cells. In bacteria, this is a uni-directional transfer of genetic material; in protozoa it is a bi-directional exchange. In algae and fungi, it is a form of sexual reproduction, with the union of male and female gametes.Bacterial Infections: Infections by bacteria, general or unspecified.Bacterial Outer Membrane Proteins: Proteins isolated from the outer membrane of Gram-negative bacteria.Anti-Infective Agents: Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.Czech Republic: Created 1 January 1993 as a result of the division of Czechoslovakia into the Czech Republic and Slovakia.Clavulanic Acid: Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.O Antigens: The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.Housekeeping, Hospital: Hospital department which manages and provides the required housekeeping functions in all areas of the hospital.Sorbic Acid: Mold and yeast inhibitor. Used as a fungistatic agent for foods, especially cheeses.Lice Infestations: Parasitic attack or subsistence on the skin by members of the order Phthiraptera, especially on humans by Pediculus humanus of the family Pediculidae. The hair of the head, eyelashes, and pubis is a frequent site of infestation. (From Dorland, 28th ed; Stedman, 26th ed)Gene Transfer, Horizontal: The naturally occurring transmission of genetic information between organisms, related or unrelated, circumventing parent-to-offspring transmission. Horizontal gene transfer may occur via a variety of naturally occurring processes such as GENETIC CONJUGATION; GENETIC TRANSDUCTION; and TRANSFECTION. It may result in a change of the recipient organism's genetic composition (TRANSFORMATION, GENETIC).Oxidoreductases, O-Demethylating: Drug metabolizing enzymes which oxidize methyl ethers. Usually found in liver microsomes.Aldehyde Oxidoreductases: Oxidoreductases that are specific for ALDEHYDES.Random Amplified Polymorphic DNA Technique: Technique that utilizes low-stringency polymerase chain reaction (PCR) amplification with single primers of arbitrary sequence to generate strain-specific arrays of anonymous DNA fragments. RAPD technique may be used to determine taxonomic identity, assess kinship relationships, analyze mixed genome samples, and create specific probes.Fomites: Inanimate objects that carry pathogenic microorganisms and thus can serve as the source of infection. Microorganisms typically survive on fomites for minutes or hours. Common fomites include CLOTHING, tissue paper, hairbrushes, and COOKING AND EATING UTENSILS.Rifampin: A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.TaiwanKetosesQuinolones: A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.Mutagenesis, Insertional: Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.Fluoroquinolones: A group of QUINOLONES with at least one fluorine atom and a piperazinyl group.TurkeyRepublic of Korea: The capital is Seoul. The country, established September 9, 1948, is located on the southern part of the Korean Peninsula. Its northern border is shared with the Democratic People's Republic of Korea.Benzyl Alcohols: Alcohols derived from the aryl radical (C6H5CH2-) and defined by C6H5CHOH. The concept includes derivatives with any substituents on the benzene ring.Sugar AcidsEsterasesTertiary Healthcare: Care of a highly technical and specialized nature, provided in a medical center, usually one affiliated with a university, for patients with unusually severe, complex, or uncommon health problems.Kingella: A genus of gram-negative, aerobic, rod-shaped bacteria whose organisms are part of the normal flora of the mucous membranes of the upper respiratory tract. Some species are pathogenic for man.Hospitals, Teaching: Hospitals engaged in educational and research programs, as well as providing medical care to the patients.Benzyl Alcohol: A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.Transformation, Genetic: Change brought about to an organisms genetic composition by unidirectional transfer (TRANSFECTION; TRANSDUCTION, GENETIC; CONJUGATION, GENETIC, etc.) and incorporation of foreign DNA into prokaryotic or eukaryotic cells by recombination of part or all of that DNA into the cell's genome.Korea: Former kingdom, located on Korea Peninsula between Sea of Japan and Yellow Sea on east coast of Asia. In 1948, the kingdom ceased and two independent countries were formed, divided by the 38th parallel.Cephalosporins: A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.EstersPolysaccharides, Bacterial: Polysaccharides found in bacteria and in capsules thereof.Coumaric Acids: Hydroxycinnamic acid and its derivatives. Act as activators of the indoleacetic acid oxidizing system, thereby producing a decrease in the endogenous level of bound indoleacetic acid in plants.Equipment Contamination: The presence of an infectious agent on instruments, prostheses, or other inanimate articles.BenzaldehydesPenicillanic Acid: A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)Myoviridae: A family of BACTERIOPHAGES and ARCHAEAL VIRUSES which are characterized by complex contractile tails.Military Personnel: Persons including soldiers involved with the armed forces.Mixed Function Oxygenases: Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.Malaysia: A parliamentary democracy with a constitutional monarch in southeast Asia, consisting of 11 states (West Malaysia) on the Malay Peninsula and two states (East Malaysia) on the island of BORNEO. It is also called the Federation of Malaysia. Its capital is Kuala Lumpur. Before 1963 it was the Union of Malaya. It reorganized in 1948 as the Federation of Malaya, becoming independent from British Malaya in 1957 and becoming Malaysia in 1963 as a federation of Malaya, Sabah, Sarawak, and Singapore (which seceded in 1965). The form Malay- probably derives from the Tamil malay, mountain, with reference to its geography. (From Webster's New Geographical Dictionary, 1988, p715 & Room, Brewer's Dictionary of Names, 1992, p329)Chenopodiaceae: The goosefoot plant family of the order Caryophyllales, subclass Caryophyllidae, class Magnoliopsida. It includes beets and chard (BETA VULGARIS), as well as SPINACH, and salt tolerant plants.Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.Pseudomonas putida: A species of gram-negative, aerobic bacteria isolated from soil and water as well as clinical specimens. Occasionally it is an opportunistic pathogen.Genomic Islands: Distinct units in some bacterial, bacteriophage or plasmid GENOMES that are types of MOBILE GENETIC ELEMENTS. Encoded in them are a variety of fitness conferring genes, such as VIRULENCE FACTORS (in "pathogenicity islands or islets"), ANTIBIOTIC RESISTANCE genes, or genes required for SYMBIOSIS (in "symbiosis islands or islets"). They range in size from 10 - 500 kilobases, and their GC CONTENT and CODON usage differ from the rest of the genome. They typically contain an INTEGRASE gene, although in some cases this gene has been deleted resulting in "anchored genomic islands".ArgentinaBacterial Adhesion: Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.Restriction Mapping: Use of restriction endonucleases to analyze and generate a physical map of genomes, genes, or other segments of DNA.Dioxygenases: Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS; GIBBERELLINS; and HYOSCYAMINE; and for degradation of AROMATIC HYDROCARBONS.Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.Burn Units: Specialized hospital facilities which provide intensive care for burn patients.Bacterial Load: Measurable quantity of bacteria in an object, organism, or organism compartment.RNA, Bacterial: Ribonucleic acid in bacteria having regulatory and catalytic roles as well as involvement in protein synthesis.Acyl-Butyrolactones: Cyclic esters of acylated BUTYRIC ACID containing four carbons in the ring.Substrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.DNA Gyrase: A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting of two A and two B subunits. In the presence of ATP, gyrase is able to convert the relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.
Microbial and chemical transformations of some 12,13-epoxytrichothec-9,10-enes. (1/991)
Resting cells of Streptomyces griseus, Mucor mucedo, and a growing culture of Acinetobacter calcoaceticus when mixed with compounds related to 12,13-epoxytrichothec-9-ene-4beta,15-diacetoxy-3alpha-ol(anguidine) produced a series of derivatives that were either partially hydrolyzed or selectively acylated. These derivatives showed marked differences in activities as assayed by antifungal and tissue culture cytotoxicity tests. (+info)Effect of desiccation on the ultrastructural appearances of Acinetobacter baumannii and Acinetobacter lwoffii. (2/991)
An Acinetobacter baumannii isolate survived desiccation beyond 30 days and an Acinetobacter lwoffii isolate up to 21 days. For both species, desiccation resulted in a significant increase in the proportion of round cells (A baumannii, 40% to 80%; A lwoffii, 51% to 63%) and a significant decrease in rod shaped cells (A baumannii, 58% to 13%; A lwoffii, 46% to 34%). Electronmicroscopic examination showed that there was also a corresponding significant increase in the cell wall thickness (A baumannii, up to 53%; A lwoffii, up to 26%). Desiccated A baumannii cells became more electron-dense and had significantly thicker cell walls (x1.3) than those of A lwoffii. Cell wall structures of A baumannii strains with different abilities to resist desiccation deserve further study. (+info)Acinetobacter bacteremia in Hong Kong: prospective study and review. (3/991)
The epidemiological characteristics of 18 patients with acinetobacter bacteremia were analyzed. Patients (mean age, 55.5 years) developed bacteremia after an average of 14.1 days of hospitalization. Fifteen of 16 patients survived bacteremia caused by Acinetobacter baumannii. Cultures of blood from the remaining two patients yielded Acinetobacter lwoffii. Most patients (78%) resided in the general ward, while four patients (22%) were under intensive care. Genotyping by arbitrarily primed polymerase chain reaction analysis and the temporal sequence of isolation were more useful than phenotyping by antimicrobial susceptibility in the determination of the source of bacteremia, and the intravascular catheter was the leading infection source (39% of cases). The possibility of an association of glucose with the pathogenesis of acinetobacter infection was raised. (+info)Risk factors for nosocomial bloodstream infections due to Acinetobacter baumannii: a case-control study of adult burn patients. (4/991)
Risk factors for Acinetobacter baumannii bloodstream infection (BSI) were studied in patients with severe thermal injury in a burn intensive care unit where A. baumannii was endemic. Of 367 patients hospitalized for severe thermal injury during the study period, 29 patients with nosocomial A. baumannii BSI were identified (attack rate, 7.9%). Cases were compared with 58 matched controls without A. baumannii BSI. The overall mortality rate was 31% among cases and 14% among controls; only two deaths (7%) were considered directly related to A. baumannii BSI. Molecular typing of A. baumannii blood isolates by means of randomly amplified polymorphic DNA analysis and pulsed-field gel electrophoresis revealed the presence of three different strain types. Multivariate analysis showed that female gender (P = .027), total body surface area burn of > 50% (P = .016), prior nosocomial colonization with A. baumannii at a distant site (P = .0002), and use of hydrotherapy (P = .037) were independently associated with the acquisition of A. baumannii BSI in burn patients. These data underscore the need for effective infection control measures for this emerging nosocomial problem. (+info)Phylogenetic structures of the genus Acinetobacter based on gyrB sequences: comparison with the grouping by DNA-DNA hybridization. (5/991)
The phylogenetic relationships of 49 Acinetobacter strains, 46 of which have previously been classified into 18 genomic species by DNA-DNA hybridization studies, were investigated using the nucleotide sequence of gyrB, the structural gene for the DNA gyrase B subunit. The phylogenetic tree showed linkages between genomic species 1 (Acinetobacter calcoaceticus), 2 (Acinetobacter baumannii), 3 and TU13; genomic species 6, BJ15, BJ16 and BJ17; genomic species 5, BJ13 (synonym of TU14) and BJ14; genomic species 7 (Acinetobacter johnsonii), 10 and 11; and genomic species 8 and 9. The phylogenetic grouping of Acinetobacter strains based on gyrB genes was almost congruent with that based on DNA-DNA hybridization studies. Consequently, gyrB sequence comparison can be used to resolve the taxonomic positions of bacterial strains at the level of genomic species. However, minor discrepancies existed in the grouping of strains of genomic species 8, 9 and BJ17. The phylogenetic tree for these strains was reconstructed from the sequence of rpoD, the structural gene for the RNA polymerase sigma 70 factor. The latter tree was 100% congruent with the grouping based on DNA-DNA hybridization. The reliability of DNA-DNA hybridization may be superior to that of sequence comparison of a single protein-encoding gene in resolving closely related organisms since the former method measures the homologies between the nucleotide sequences of total genomic DNAs. Three strains that have not been characterized previously by DNA-DNA hybridization seem to belong to two new genomic species, one including strain ATCC 33308 and the other including strains ATCC 31012 and MBIC 1332. (+info)Efficacy of sulbactam alone and in combination with ampicillin in nosocomial infections caused by multiresistant Acinetobacter baumannii. (6/991)
From March 1995 to March 1997, sulbactam was prospectively evaluated in patients with non-life-threatening multiresistant Acinetobacter baumannii infections. During this period, 47 patients were treated with sulbactam; of them, five were excluded because they had received < or =48 h of sulbactam therapy. A total of 42 patients, 27 males and 15 females with a mean age of 60+/-15 years, were finally evaluated. Infections were as follows: surgical wound, 19; tracheobronchitis, 12; urinary tract, 7; catheter-related bacteraemia, 2; and pneumonia, 2. Eighteen patients received intravenous sulbactam alone (1 g every 8 h) and 24 patients received intravenous sulbactam/ampicillin (1 g:2 g every 8 h) with no major adverse effects. Of the 42 patients, 39 improved or were cured and showed A. baumannii eradication and one patient had persistence of wound infection after 8 days of sulbactam/ampicillin requiring surgical debridement. Two patients died after 3 days of therapy (one of the deaths was attributable to A. baumannii infection). The in-vitro activity of the sulbactam/ampicillin combination was by virtue of the antimicrobial activity exhibited by sulbactam. Killing curves showed that sulbactam was bacteriostatic; no synergy was observed between ampicillin and sulbactam. Our results indicate that sulbactam may prove effective for non-life-threatening A. baumannii infections. Its role in the treatment of severe infections is unknown. However, the current formulation of sulbactam alone may allow its use at higher doses and provide new potential synergic combinations, particularly for those infections by A. baumannii resistant to imipenem. (+info)Engineering a chimeric pyrroloquinoline quinone glucose dehydrogenase: improvement of EDTA tolerance, thermal stability and substrate specificity. (7/991)
An engineered Escherichia coli PQQ glucose dehydrogenase (PQQGDH) with improved enzymatic characteristics was constructed by substituting and combining the gene-encoding protein regions responsible for EDTA tolerance, thermal stability and substrate specificity. The protein region responsible for complete EDTA tolerance in Acinetobacter calcoaceticus, which is recognized as the indicator of high stability in co-factor binding, was elucidated. The region is located between 32 and 59% from the N-terminus of A. calcoaceticus PQQGDH(A27 region) and also corresponds to the same position from 32 to 59% from the N-terminus in E. coli PQQGDH, though E. coli PQQGDH is EDTA sensitive. We previously reported that the C-terminal 3% region of A. calcoaceticus (A3 region) played an important role in the increase of thermal stability, and that His775Asn substitution in E. coli PQQGDH resulted in an increase in the substrate specificity of E. coli PQQGDH towards glucose. Based on these findings, chimeric and/or mutated PQQGDHs, E97A3 H775N, E32A27E41 H782N, E32A27E38A3 and E32A27E38A3 H782N were constructed to investigate the compatibility of two protein regions and one amino acid substitution. His775 substitution to Asn corresponded to His782 substitution to Asn (H782N) in chimeric enzymes harbouring the A27 region. Since all the chimeric PQQGDHs harbouring the A27 region were EDTA tolerant, the A27 region was found to be compatible with the other region and substituted amino acid responsible for the improvement of enzymatic properties. The contribution of the A3 region to thermal stability complemented the decrease in the thermal stability due to the His775 or His782 substitution to Asn. E32A27E38A3 H782N, which harbours all the above mentioned three regions, showed improved EDTA tolerance, thermal stability and substrate specificity. These results suggested a strategy for the construction of a semi-artificial enzyme by substituting and combining the gene-encoding protein regions responsible for the improvement of enzyme characteristics. The characteristics of constructed chimeric PQQGDH are discussed based on the predicted model, beta-propeller structure. (+info)On the binding of ATP to the autophosphorylating protein, Ptk, of the bacterium Acinetobacter johnsonii. (8/991)
The autophosphorylating protein, Ptk, of the bacterium Acinetobacter johnsonii was overproduced, purified to homogeneity and assayed for ATP binding by using the nucleotide analog 5'-p-fluorosulfonylbenzoyl adenosine. The ATP binding site of this bacterial autophosphorylating protein was found to be different from that generally used by eukaryotic protein kinases. It consists of two amino acid sequences that closely resemble the Walker motifs A and B. This observation was confirmed by site-directed mutagenesis experiments which showed, in addition, that the ATP molecule bound to these motifs is effectively employed by the bacterial protein to autophosphorylate on tyrosine. It is concluded that even though the overall autophosphorylation reaction is similar in eukaryotic and prokaryotic proteins, the mechanism involved is likely different. (+info)Acinetobacter species • Aeromonas hydrophila • Bacillus brevis • Bacillus Cereus • Bacillus megaterium • Bacillus subtilis • ...
Acinetobacter johnsonii Frequent occasionally pathogenic Pseudomonas aeruginosa Infrequent occasionally pathogenic Fungal[edit] ...
Acinetobacter infections Acinetobacter baumannii Actinomycosis Actinomyces israelii, Actinomyces gerencseriae and ...
Acinetobacter baumanii; Epidemiology of Highly Pathogenic Microorganisms; Epidemiologically Modelling of Infectious Diseases; ...
and Acinetobacter sp. Glutamate carboxypeptidase II Goldman, P.; Levy, C.C. (1967). "Carboxypeptidase G: purification and ...
Towner K J (2008). "Molecular Basis of Antibiotic Resistance in Acinetobacter spp.". Acinetobacter Molecular Biology. www. ... Use of colistin to treat Acinetobacter baumannii infections has led to the development of resistant bacterial strains. which ... ISBN 0-306-43902-6. Benifla M, Zucker G, Cohen A, Alkan M (2004). "Successful treatment of Acinetobacter meningitis with ... Colistimethate sodium has also been given intrathecally and intraventricularly in Acinetobacter baumannii and Pseudomonas ...
Acinetobacter species are able to survive on various surfaces (both moist and dry) in the hospital environment, thereby being ... The genus Acinetobacter is a group of Gram-negative, nonmotile and nonfermentative bacteria belonging to the family ... In addition, Acinetobacter is uniquely suited to exploitation for biotechnological purposes. Cornelis P (editor). (2008). ... A few members are opportunistic pathogens, such as species of Pseudomonas, Moraxella, and Acinetobacter, which may cause ...
Interestingly, Acinetobacter sp. shows both quorum sensing and quorum quenching activity. It produces AHLs and also, it can ... It has recently been found that Acinetobacter sp. also show quorum sensing activity. This bacterium, an emerging pathogen, ... Co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia". BMC Microbiology. 11 (1): 51. doi: ... Co-existence of Quorum Quenching and Quorum Sensing in Acinetobacter and Burkholderia". BMC Microbiology. 11 (1): 51. doi: ...
Examples of gram-negative diplococci are Neisseria spp., Moraxella catarrhalis, and Acinetobacter spp. Examples of gram- ...
In addition to pseudomas, Acinetobacter sp. SYF26 was isolated from the Hei He reservoir in China. Genomic analysis revealed a ... Acinetobacter sp. SYF26". Microbiology. 161 (4): 829-837. doi:10.1099/mic.0.000047. Takaya, Naoki; Catalan-Sakairi, Maria; ...
Used to treat XDR Acinetobacter baumannii infections. Tolcapone - used in patients with Parkinson's disease who are not ...
It is also capable of binding to the PBP of Bacteroides fragilis and Acinetobacter spp., even when it is given alone. The ... and Acinetobacter calcoaceticus. Examples of skin conditions treated with ampicillin-sulbactam are moderate to severe diabetic ... activity of sulbactam against Acinetobacter spp. seen in in-vitro studies makes it distinctive compared to other β-lactamase ...
"НПО "Биомед" разрабатывает препарат бактериофага против Acinetobacter , РИА Новости". Ria.ru. Retrieved 2014-08-13. ""Микроген ... the company received the first samples of bacteriophage preparation against the pathogen Acinetobacter, which is the causative ...
Duine JA, Frank J, van Zeeland JK (1979). "Glucose dehydrogenase from Acinetobacter calcoaceticus: a 'quinoprotein'". FEBS Lett ...
Matsushita, K.; Shinagawa, E.; Adachi, O.; Ameyama, M. (1989). "Quinoprotein D-glucose dehydrogenase of the Acinetobacter ... Geiger, O.; Gorisch, H. (1986). "Crystalline quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus". Biochemistry ... "Cloning of the gene encoding quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus: evidence for the presence of ... "Soluble and membrane-bound quinoprotein D-glucose dehydrogenases of the Acinetobacter calcoaceticus : the binding process of ...
Davey JF, Trudgill PW (1977). "The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species". Eur. J. Biochem. 74 (1 ... Donoghue NA, Trudgill PW (1975). "The metabolism of cyclohexanol by Acinetobacter NCIB 9871". Eur. J. Biochem. 60 (1): 1-7. doi ...
Morgan RD, Dalton M, Stote R (September 1987). "A unique type II restriction endonuclease from Acinetobacter lwoffi N". Nucleic ... a new restriction endonuclease from Acinetobacter calcoaceticus". Nucleic Acids Res. 13 (24): 8685-94. doi:10.1093/nar/13.24. ... a new restriction endonuclease from Acinetobacter calcoaceticus recognizing 5'-AA^CGTT-3'". Nucleic Acids Res. 20 (14): 3787. ... a novel restriction endonuclease from Acinetobacter calcoaceticus BS (Article in russian)". Prikl Biokhim Mikrobiol. 33 (5): ...
Donoghue NA, Trudgill PW (1975). "The metabolism of cyclohexanol by Acinetobacter NCIB 9871". Eur. J. Biochem. 60 (1): 1-7. doi ...
Arunachalam, M; Mohan, N; Sugadev, R; Chellappan, P; Mahadevan, A (2003). "Degradation of (+)-catechin by Acinetobacter ... Among bacteria, degradation of (+)-catechin can be achieved by Acinetobacter calcoaceticus. Catechin is metabolized to ...
"Deciphering the Multifactorial Nature of Acinetobacter baumannii Pathogenicity". PLoS ONE. 6 (8): e22674. doi:10.1371/journal. ...
... degradation has been characterized in the bacterium Acinetobacter johnsonii.[12] C5H8O2 + O2 → C2H4O2 + C3H4O2. ... "Acetylacetone-cleaving enzyme Dke1: a novel C-C-bond-cleaving enzyme from Acinetobacter johnsonii". Biochem. J. 369 (3): 573- ...
Acinetobacter radioresistens strain AIMST Nalbe6 16S ribosomal RNA gene, partial sequence. NCBI. Acinetobacter soli strain ... Acinetobacter calcoaceticus strain AIMST Nalbe4 16S ribosomal RNA gene, partial sequence. NCBI. Acinetobacter calcoaceticus ... Acinetobacter calcoaceticus strain AIMST Ngme3 16S ribosomal RNA gene, partial sequence. NCBI. Acinetobacter calcoaceticus ... Acinetobacter radioresistens strain AIMST Nalbe6 (N. alba; Mount Jerai, Kedah, Malaysia; leaf tissue) Acinetobacter soli strain ...
Acinetobacter strains may grow on solid media as coccobacilli. Bordetella pertussis is a Gram-negative coccobacillus ...
Acinetobacter strains may grow on solid media as coccobacilli. Coxiella burnetti is also a coccobacillus. Important human ...
"Medscape abstract on Acinetobacter baumannii: Acinetobacter baumannii: An Emerging Multidrug-resistant Threat". membership only ... Acinetobacter is a gram-negative bacteria that causes pneumonia or bloodstream infections in critically ill patients. Multidrug ... On November 5, 2004, the Centers for Disease Control and Prevention (CDC) reported an increasing number of Acinetobacter ... Centers for Disease Control Prevention (CDC). (2004). "Acinetobacter baumannii infections among patients at military medical ...
Retrieved from "https://en.wikipedia.org/w/index.php?title=Talk:Acinetobacter_calcoaceticus&oldid=587086953" ...
Vernacular names [edit wikidata Category:Acinetobacter linked to current category] [edit wikidata Acinetobacter main topic ... NCBI link: Acinetobacter Brisou & Prevot 1954 *World Register of Marine Species link: Acinetobacter Brisou & Prevot, 1954 (+ ... Media in category "Acinetobacter". The following 3 files are in this category, out of 3 total. ... Structure of Catechol 1,2-dioxygenase from Acinetobacter Calcoaceticus Native Data.jpg 500 × 500; 48 KB. ...
Acinetobacter baumannii is one of the most frequently isolated bacteria in the ICU but significant regional differences exist. ... Acinetobacter baumannii is a gram-negative aerobic bacillus that primarily causes hospital-acquired infections affecting ... Purpose of review: We reviewed recent data about epidemiology of Acinetobacter baumannii, resistance mechanisms, and ...
Acinetobacter is a group of germs that can cause infections in the blood, urinary tract and pneumonia, typically in patients in ... Acinetobacter is a group of bacteria (germs) commonly found in the environment, like in soil and water. While there are many ... Acinetobacter baumannii can cause infections in the blood, urinary tract, and lungs (pneumonia), or in wounds in other parts of ... What is CDC doing to address Acinetobacter infections?. CDC tracks the germ, and the infections it can cause, through its ...
In healthy individuals, Acinetobacter colonies on the skin correlate with low incidence of allergies; Acinetobacter is thought ... The genus Acinetobacter comprises 38 validly named species. Identification of Acinetobacter species is complicated by lack of ... Parte, A.C. "Acinetobacter". www.bacterio.net. "Acinetobacter: Bacteria - Cofactor Ora". cofactor.io. Retrieved December 19, ... allows some Acinetobacter species to survive in a hospital environment. Furthermore, Acinetobacter species can grow at a broad ...
Bacteria of the Acinetobacter ACB complex, which are frequently acquired in hospital settings, can also be found in beef meat, ... The antibiotic-resistant Acinetobacter baumannii bacterium is one of the most globally harmful bacteria that causes nosocomial ... Antibiotic-resistant Acinetobacter baumannii infections, one of the most common hospital-acquired infections in children across ... In the first national study of the prevalence of antibiotic-resistant Acinetobacter baumannii infections in children across the ...
Acinetobacter baumannii is a pleomorphic aerobic gram-negative bacillus (similar in appearance to Haemophilus influenzae on ... encoded search term (Acinetobacter) and Acinetobacter What to Read Next on Medscape. Medscape Consult. ... Acinetobacter activity, and their use may predispose to Acinetobacter colonization. Some strains are sensitive to cefepime, ... Clonal spread of Acinetobacter baumannii in a general intensive care unit. Ann Ig. 2004 Jan-Apr. 16(1-2):95-102. [Medline]. ...
"Acinetobacter bereziniae sp. nov. And Acinetobacter guillouiae sp. nov., to accommodate Acinetobacter genomic species 10 and 11 ... Acinetobacter guillouiae is a Gram-negative, strictly aerobic bacterium from the genus Acinetobacter isolated from gas-works ... LPSN bacterio.net Straininfo of Acinetobacter guillouiae Nemec, A.; Musilek, M.; Sedo, O.; De Baere, T.; Maixnerova, M.; Van ... Taxonomy Browser ATCC Type strain of Acinetobacter guillouiae at BacDive - the Bacterial Diversity Metadatabase. ...
Acinetobacter definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up ... acinetobacter. noun. *a bacterium that causes infections such as pneumonia, particularly in people who have a compromised ... acinetobacter. C20: from Greek acetinae immovable + bacter (ium). Collins English Dictionary - Complete & Unabridged 2012 ...
Rather than being a single type of bacterium Acinetobacter is made up of over 25 varieties. ... Acinetobacter bacteria are present in water, soil and sewage. ... Acinetobacter: A Look at Bad Bacteria. Acinetobacter bacteria ... Treating Acinetobacter Bacteria. The difficulty that medical personnel have when an Acinetobacter infection occurs is that it ... Symptoms of Acinetobacter Bacteria Infection. A person who has become infected with Acinetobacter bacteria may develop ...
Acinetobacter baumannii is a pleomorphic aerobic gram-negative bacillus (similar in appearance to Haemophilus influenzae on ... encoded search term (Acinetobacter) and Acinetobacter What to Read Next on Medscape. Related Conditions and Diseases. * ... The most common infection-causing species is A baumannii, followed by Acinetobactercalcoaceticus and Acinetobacterlwoffii. [1] ... Acinetobacter commonly colonizes patients in the intensive care setting. Acinetobacter colonization is particularly common in ...
Acinetobacter baumannii is the cause of difficult-to-treat infections in healthcare settings in Europe due to its increasing ...
Your basket is currently empty. i ,p>When browsing through different UniProt proteins, you can use the basket to save them, so that you can back to find or analyse them later.,p>,a href=/help/basket target=_top>More...,/a>,/p> ...
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ATCC ® 49467D™ Designation: Genomic DNA from Acinetobacter sp. strain AmMS 248 TypeStrain=False Application: ... Acinetobacter sp. (ATCC® 49467D™) Strain Designations: Genomic DNA from Acinetobacter sp. strain AmMS 248 [ATCC® 49467™] / Type ... Genomic DNA from Acinetobacter sp. strain AmMS 248 [ATCC® 49467™] Biosafety Level 1 Biosafety classification is based on U.S. ...
... Designation: S2 TypeStrain=False Application: Assay of cefoperazone Assay of sulbactam ... Acinetobacter baumannii (ATCC® 43498™) Strain Designations: S2 / Type Strain: no / Biosafety Level: 2 ...
... Designation: AmMS 203 TypeStrain=False Application: Quality control strain Quality control ... Acinetobacter sp. (ATCC® 49137™) Strain Designations: AmMS 203 / Type Strain: no / Biosafety Level: 2 ...
Each antibiotic is presented in three columns. The first column lists the name of the antibiotic. The middle column represents susceptibility in percent to that antibiotic. The 3rd column represents the number of isolates tested for that specific antibiotic ...
Patients with Acinetobacter pneumonias occurring in the context of an outbreak in the intensive care unit (IC... more ... Prolonged hospitalization or antibiotic therapy predisposes to Acinetobacter colonization. ... Drugs & Diseases , Infectious Diseases , Acinetobacter Q&A Which clinical history findings are characteristic of Acinetobacter ... Prolonged hospitalization or antibiotic therapy predisposes to Acinetobacter colonization.. Patients with Acinetobacter ...
Acinetobacter Brisou et Prévot 1954, in "Bergeys Manual of Systematic Bacteriology, vol.1," p.303, N.R. Grieg and J.G. Holt, ... Members of the genus Acinetobacter can frequently be isolated from healthy people and are also commonly present in soil and ... Poh, C.L., and Loh, G.K., 1985, Enzymatic profile of clinical isolates of Acinetobacter calcoaceticus, Med. Microbiol. Immunol. ... Avril JL., Mesnard R. (1991) Factors Influencing the Virulence of Acinetobacter. In: Towner K.J., Bergogne-Bérézin E., Fewson C ...
Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesis.. Jacobs AC1, Hood I, Boyd KL, Olson PD, ... Acinetobacter baumannii is an emerging bacterial pathogen of considerable health care concern. Nonetheless, relatively little ...
Isolation of tetD, tetC, tetB, tetA genes from Acinetobacter bummani samples isolated from hospital samples by multiplex PCR ... The Frequency of blaPER، blaVEB، blaCTX-M، tetA and tetB genes among Acinetobacter baumannii strains isolated from hospitalizes ... Assessment of Frequency and antibiotic resistance pattern of Acinetobacter spp. isolated from traumatic patients in Shahid ... Probiotics in Goat Milk: A Promising Solution for Management of Drug-Resistant Acinetobacter baumannii ...
Retrieved from "https://species.wikimedia.org/w/index.php?title=Acinetobacter_virus_Fri1&oldid=5475707" ...
Multidrug-resistant Acinetobacter baumannii (MDR-AB) was found in the environment of 48 percent of the rooms of patients ... Acinetobacter baumannii is a species of gram-negative, multidrug resistant bacteria that has caused outbreaks of infection in ... Washington, DC, November 1, 2011 -- Multidrug-resistant Acinetobacter baumannii (MDR-AB) was found in the environment of 48 ... the study did not evaluate healthcare worker or patient movement and therefore cannot demonstrate transmission of Acinetobacter ...
Gutnick D. Potential Application of Acinetobacter in Biotechnology in Acinetobacter Molecular Biology. Gerischer U (editor), ... In healthy humans, it is normal to have some amount of Acinetobacter on the skin surface; as many as 25% of healthy adults do ... Acinetobacter cells are Gram-negative short rods (coccobacilli), measuring 1.0-1.5 by 1.5-2.5 microns during growth; they often ... Acinetobacter. Houston Medical School, University of Texas. 1995.. Herper, Matthew. The Iraq Infection. Forbes.com, August 2 ...
- Acinetobacter species are oxidase-negative, exhibit twitching motility, and occur in pairs under magnification. (wikipedia.org)
- Acinetobacter species are a key source of infection in debilitated patients in the hospital, in particular the species Acinetobacter baumannii. (wikipedia.org)
- Species of the genus Acinetobacter are strictly aerobic, nonfermentative, Gram-negative bacilli. (wikipedia.org)
- The morphology of Acinetobacter species can be quite variable in Gram-stained human clinical specimens, and cannot be used to differentiate Acinetobacter from other common causes of infection. (wikipedia.org)
- The genus Acinetobacter comprises 38 validly named species. (wikipedia.org)
- Identification of Acinetobacter species is complicated by lack of standard identification techniques. (wikipedia.org)
- Acinetobacter species are widely distributed in nature, and commonly occur in soil and water. (wikipedia.org)
- Their ability to survive on moist and dry surfaces, as well as to survive exposure to various common disinfectants, allows some Acinetobacter species to survive in a hospital environment. (wikipedia.org)
- Furthermore, Acinetobacter species can grow at a broad range of temperatures, allowing them to survive in a broad array of environments. (wikipedia.org)
- The Acinetobacter has more than 50 species, most of which are nonpathogenic environmental organisms. (medscape.com)
- Acinetobacter species have low virulence but are capable of causing infection in organ transplants and febrile neutropenia. (medscape.com)
- Acinetobacter species are can be transmitted to patients because of their persistence on environmental surfaces and because of colonization of the hands of healthcare workers. (medscape.com)
- Update on acinetobacter species: mechanisms of antimicrobial resistance and contemporary in vitro activity of minocycline and other treatment options. (medscape.com)
- A. baumannii is now the most prevalent Acinetobacter species isolated from clinical specimens, but for historical reasons this review will refer to Acinetobacter without detailed consideration of individual species. (springer.com)
- Acinetobacter baumannii is a species of gram-negative, multidrug resistant bacteria that has caused outbreaks of infection in healthcare facilities over the last decade and considerable concern in the medical community. (elsevier.com)
- Acinetobacter is a genus of opportunistic pathogens in the proteobacteria group, species of which are distributed in widespread, diverse habitats. (kenyon.edu)
- It has garnered media attention because of an outbreak among soldiers in Iraq who contracted the species Acinetobacter baumannii . (kenyon.edu)
- Because Acinetobacters are very resistant to antibiotics and are difficult to differentiate between species when isolated from patients, learning more about their DNA will help develop better drugs to control outbreaks of the infection. (kenyon.edu)
- Blood culture grew Acinetobacter species. (hindawi.com)
- Members of the genus Acinetobacter are ubiquitous in the environment and the multiple-drug resistant species A. baumannii is of significant clinical concern. (mdpi.com)
- It has garnered media attention because of an outbreak among soldiers in Iraq who contracted the species Acinetobacter baumannii from the Iraqi soil. (kenyon.edu)
- Acinetobacter species are gram-negative, non-fermenting, often coccobacillary bacteria that belong in the family Moraxellaceae. (neurologyadvisor.com)
- Acinetobacter species are widely distributed in nature and the hospital environment and can survive on moist and dry surfaces, and may be present in foodstuffs and on healthy skin. (neurologyadvisor.com)
- Since it remains unclear how to treat bacteremia caused by AB, the present study aims to enroll patients at multiple sites with extensively drug resistant Acinetobacter species bacteremia receiving different combination therapy to assess treatment outcomes and analyze risk factors associated with mortality. (clinicaltrials.gov)
- Blood sample will be collected on the day of enrollment (Day 0), Day 1, 2, 3 and 7 for PCR identification and quantification of Acinetobacter species. (clinicaltrials.gov)
- Characterization of intracytoplasmic hydrocarbon inclusions from the hydrocarbon-oxidizing Acinetobacter species HO1-N. (asm.org)
- Body lice that fed on rabbits infused with each Acinetobacter species demonstrated a generalized infection. (ajtmh.org)
- The lice excreted living Acinetobacter species within their feces. (ajtmh.org)
- Distribution of Acinetobacter species on skin of healthy humans. (ajtmh.org)
- Over the past four years MDR Acinetobacter and Pan-resistant Acinetobacter species have been showing up in patients referred to our facility. (wiredprnews.com)
- Determines the citywide prevalence and inter-hospital spread of endemic carbapenem-resistant Acinetobacter species in Brooklyn, New York. (ebscohost.com)
- Among Acinetobacter genus, Acinetobacter baumannii, Acinetobacter nosocomialis and Acinetobacter pittii are the most clinically relevant species. (antimicrobe.org)
- ARDRA and AFLP analysis are the reference methods for species identification in all Acinetobacter spp. (antimicrobe.org)
- OXA-23-producing Acinetobacter species from horses: a public health hazard? (ugent.be)
- OXA-23-producing Acinetobacter species from hor. (ugent.be)
- TY - JOUR UR - http://lib.ugent.be/catalog/pug01:3092785 ID - pug01:3092785 LA - eng TI - OXA-23-producing Acinetobacter species from horses: a public health hazard? (ugent.be)
- Acinetobacter is a group of bacteria (germs) commonly found in the environment, like in soil and water. (cdc.gov)
- Acinetobacter (/ˌæsɪˈniːtoʊbæktər/) is a genus of Gram-negative bacteria belonging to the wider class of Gammaproteobacteria. (wikipedia.org)
- Bacteria of the genus Acinetobacter are known to form intracellular inclusions of polyhydroxyalkanoates under certain environmental conditions (e.g. lack of elements such as phosphorus, nitrogen, or oxygen combined with an excessive supply of carbon sources). (wikipedia.org)
- Bacteria of the Acinetobacter ACB complex, which are frequently acquired in hospital settings, can also be found in beef meat, according to a study led by ISGlobal, an institution supported by "la Caixa" and performed with meat samples from markets in Lima, Peru. (news-medical.net)
- Acinetobacter bacteria are fairly common microbes that can be found in many parts of the environment. (brighthub.com)
- Acinetobacter bacteria can be an issue for people who have been admitted to hospital. (brighthub.com)
- A person who has become infected with Acinetobacter bacteria may develop pneumonia-like symptoms. (brighthub.com)
- Staff that come into contact with patients infected with Acinetobacter bacteria are encouraged to wear gloves and gowns to reduce the risk of spreading the infection. (brighthub.com)
- it is the last test which is most used to distinguish Acinetobacter from other infective bacteria. (kenyon.edu)
- Acinetobacters are widely distributed in hospitals, where they pose the danger of transferring resistance to other hospital-inhabiting bacteria. (kenyon.edu)
- In 1954, Brisou and PrA(c)vot proposed the genus Acinetobacter to indicate that the bacteria were nonmotile because they lacked flagella. (cdc.gov)
- Acinetobacter baumannii bacteria, coloured scanning electron micrograph (SEM). (sciencephoto.com)
- Multi-drug resistant Acinetobacter baumannii bacteria inside biofilm, computer illustration. (sciencephoto.com)
- Acinetobacter infection , also known as Acinetobacter Baumannii Infection, is caused by the Acinetobacter baumannii bacteria . (naturalpedia.com)
- Acinetobacter infection is a highly contagious disease caused by the Acinetobacter baumannii bacteria. (naturalpedia.com)
- Bacteria of the Acinetobacter genus. (ajtmh.org)
- Growth on the AMA indicates a positive transformation assay and confirms the isolate as a member of the genus Acinetobacter. (wikipedia.org)
- Acinetobacter guillouiae is a Gram-negative, strictly aerobic bacterium from the genus Acinetobacter isolated from gas-works effluent. (wikipedia.org)
- Members of the genus Acinetobacter can frequently be isolated from healthy people and are also commonly present in soil and water as free-living saprophytes. (springer.com)
- Therefore, the A1S_2225 gene, which is present in several members of the Acinetobacter genus, was named b lue- l ight- s ensing A ( blsA ). (asm.org)
- Members of the genus Acinetobacter are usually found in diploid formation, or chains of variable length. (antimicrobe.org)
- Carbapenem-resistant Acinetobacter are usually multidrug-resistant. (cdc.gov)
- Neonakis IK, Spandidos DA, Petinaki E. Confronting multidrug-resistant Acinetobacter baumannii: a review. (medscape.com)
- Optimal therapy for multidrug-resistant Acinetobacter baumannii. (medscape.com)
- Pharmacokinetic considerations regarding tigecycline for multidrug-resistant (MDR) Klebsiella pneumoniae or MDR Acinetobacter baumannii urosepsis. (medscape.com)
- Treatment of nosocomial meningitis due to a multidrug resistant Acinetobacter baumannii with intraventricular colistin. (medscape.com)
- The Epidemiology of Multidrug-Resistant Acinetobacter Baumannii Does the Community Represent a Reservoir? (cambridge.org)
- High Proportions of Multidrug-Resistant Acinetobacter spp. (mdpi.com)
- Coyne S, Rosenfeld N, Lambert T, Courvalin P, Perichon B (2010) Overexpression of resistance-nodulation-cell division pump AdeFGH confers multidrug resistance in Acinetobacter baumannii . (springer.com)
- Multidrug resistant (MDR) Acinetobacter is particularly a dangerous organism in patients who suffer with decubitus ulcers. (wiredprnews.com)
- Antibiogram of multidrug resistant Acinetobacter baumannii isolated from clinical specimens at King Hussein Medical Centre, Jordan: a retrospective analysis. (ebscohost.com)
- In one of the largest studies to measure the burden of antibiotic resistance in a low- or middle-income country, researchers at the Center for Disease Dynamics, Economics & Policy report that in-hospital mortality is significantly higher among patients infected with multi-drug resistant or extensively drug resistant pathogens including Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii. (news-medical.net)
- Acinetobacter remains one of the most challenging pathogens in the field of infectious diseases owing primarily to the uniqueness and multiplicity of its resistance mechanisms. (springer.com)
- Acinetobacter junii is associated with nosocomial pathogens including pediatric oncologic individual and bacteremia in preterm infants. (biology-online.org)
- However, it is unlikely that new antimicrobial drugs will be available in the near future to treat patients infected with gram-negative pathogens such as Acinetobacter baumannii ( 1 ). (cdc.gov)
- In this assay, a naturally competent tryptophan auxotrophic mutant of Acinetobacter baylyi (BD4 trpE27) is transformed with the total DNA of a putative Acinetobacter isolate and the transformation mixture is plated on a brain heart infusion agar. (wikipedia.org)
- A novel, plasmid-mediated, high-level tigecycline resistance tet (X) gene variant, tet (X5), was detected in a clinical Acinetobacter baumannii isolate from China in 2017. (asm.org)
- Complete genome sequence of the siphoviral bacteriophage Βϕ-R3177, which lyses an OXA-66-producing carbapenem-resistant Acinetobacter baumannii isolate. (jcvi.org)
- Outbreak of a multiply resistant Acinetobacter in a surgical intensive care unit: epidemiology and control. (medscape.com)
- Acinetobacter baumannii is a pleomorphic aerobic gram-negative bacillus (similar in appearance to Haemophilus influenzae on Gram stain) commonly isolated from the hospital environment and hospitalized patients. (medscape.com)
- Acinetobacter baumannii is a Gram-negative bacterium that is associated with hospital-acquired and ventilator-associated pneumonia. (asm.org)
- Adult Acinetobacter meningitis and its comparison with non-Acinetobacter gram-negative bacterial meningitis. (uptodate.com)
- Clinical and laboratory data of these Acinetobacter meningitis patients were studied and were compared with those of other 68 non-Acinetobacter Gram-negative bacterial meningitis (GNBM) patients. (uptodate.com)
- MDR Acinetobacter is an organism resistant to two of the five classes of drugs generally effective against gram negative organism and Pan-resistant Acinetobacter is resistant to all antibiotics. (wiredprnews.com)
- Selecting appropriate empiric and definitive antibacterial therapy for Acinetobacter is further complicated by the lack of reliability in commercial antimicrobial susceptibility testing devices and limited breakpoint interpretations for available agents. (springer.com)
- White and blue light induce reduction in susceptibility to minocycline and tigecycline in Acinetobacter spp. (sigmaaldrich.com)
- We further show that the modulation of antibiotic susceptibility occurs not only in Acinetobacter baumannii but also in other micro-organisms of clinical relevance such as Escherichia coli and Staphylococcus aureus. (sigmaaldrich.com)
- A group in the Department of Immunology, Microbiology and Parasitology at the UPV/EHU has conducted an in-depth study into the capacity to survive of the Acinetobacter baumannii bacterium as well as the strategies it uses to survive. (news-medical.net)
- The researchers investigated the microbiology databases at Oakwood Healthcare System in Michigan (four hospitals with 632, 259, 199 and 168 beds) for clinical Acinetobacter cultures obtained from 2003 to 2008. (infectioncontroltoday.com)
- Unfortunately, many Acinetobacter germs are resistant to many antibiotics, including carbapenems, which makes them difficult to treat with available antibiotics. (cdc.gov)
- Patients with Acinetobacter colonization often have a history of prolonged hospitalization or antimicrobial therapy (with antibiotics that have little or no activity against Acinetobacter ). (medscape.com)
- 4-Hydroxybenzaldehyde (4-HBA), which cannot support the growth of Acinetobacter baumannii , exhibited synergism only with amphenicol antibiotics including chloramphenicol (CAM) and thiamphenicol. (springer.com)
- Damier-Piolle L, Magnet S, Bremont S, Lambert T, Courvalin P (2008) AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii . (springer.com)
- Antibiotic-resistant Acinetobacter meningitis in neurosurgical patients. (medscape.com)
- Impact of multi-drug-resistant Acinetobacter baumannii on clinical outcomes. (medscape.com)
- Of these resistant organisms, Acinetobacter remains one of the most formidable opponents, as its unique and eclectic resistance mechanisms allow it to escape the activity of the majority of our currently available antimicrobials. (springer.com)
- There was a more than 300 percent increase in the proportion of Acinetobacter cases resistant to the antibiotic imipenem during 1999 to 2006. (rwjf.org)
- A 4-year surveillance of carbapenem-resistant Acinetobacter spp. (asm.org)
- Research from the Center for Immunology and Infectious Disease at the Queen Mary University of London has determined that curcumin , the medically active compound from the turmeric root, can significantly inhibit antibiotic-resistant forms of Acinetobacter baumannii when combined with a compound found in a number of vegetables, herbs, and nuts. (naturalpedia.com)
- A strain of Acinetobacter baumannii 6B92 isolated from the blood culture of a patient at the Edinburgh Royal Infirmary i 1985 was found to be resistant to imipenem, all classes of cephalosporins and penicillins. (nih.gov)
- pI 9.0) and a novel beta-lactomase of pI 6.65 named ARI 1 (Acinetobacter resistant to imipenem). (nih.gov)
- Among these threats, the rapid increase in carbapenem-resistant Acinetobacter baumannii (CRAB) is a particularly challenging global issue in the health care setting. (jcvi.org)
- The 2005 IDSA guidelines for hospital-acquired pneumonia discuss the role of Acinetobacter as a cause of nosocomial pneumonia. (medscape.com)
- Acinetobacter community acquired pneumonia. (visualdx.com)
- Community-acquired bacteraemic Acinetobacter pneumonia with survival. (bmj.com)
- Acinetobacter is a rare potentially fatal cause of community-acquired pneumonia. (bmj.com)
- Community-acquired Acinetobacter pneumonia: a case report. (ajtmh.org)
- According to the article in Clinical Infectious Diseases , "During this period, Acinetobacter prevalence increased 25 percent. (infectioncontroltoday.com)
- This study investigated the prevalence of P. aeruginosa and Acinetobacter spp. (scielo.br)
- Molecular characterization of the gene encoding a new AmpC ß-lactamase in Acinetobacter baylyi - ADP1 has a chromosomal copy of AmpC? (openwetware.org)
- An experimental approach to this question was presented by the heat-sensitive phenotype conferred by pcaG1102 , a 30-bp deletion in one of the structural genes for Acinetobacter baylyi protocatechuate 3,4-dioxygenase, which is required for growth with quinate. (asm.org)
- The interplay between contrasting forces, i.e., loss of DNA by sequence-guided deletion against maintenance of sequence repetition for useful function, was illustrated by genetic investigation of pcaO , the operator that governs transcription of the pca - qui operon in Acinetobacter baylyi strain ADP1. (asm.org)
- Acinetobacter pneumonias occur in outbreaks and are usually associated with colonized respiratory-support equipment or fluids. (medscape.com)
- Patients with Acinetobacter pneumonias occurring in the context of an outbreak in the intensive care unit (ICU) generally have a history of preceding contact with respiratory support monitors or equipment. (medscape.com)
- Z96926 Acinetobacter baumannii waaA gene, strain ATCC 19606. (atcc.org)
- In general, first-, second-, and third-generation cephalosporins, macrolides, and penicillins have little or no anti- Acinetobacter activity, and their use may predispose to Acinetobacter colonization. (medscape.com)
- Acinetobacter colonization is particularly common in patients who are intubated and in those who have multiple intravenous lines or monitoring devices, surgical drains, or indwelling urinary catheters. (medscape.com)
- Prolonged hospitalization or antibiotic therapy predisposes to Acinetobacter colonization. (medscape.com)
- Acinetobacter baumannii Gastrointestinal Colonization Is Facilitated by Secretory IgA Which Is Reductively Dissociated by Bacterial Thioredoxin A . mBio, Vol. 9, Issue. (cambridge.org)
- Share information about any additional Acinetobacter platelet bacterial contamination cases being investigated. (aabb.org)
- Rather than being a single type of bacterium Acinetobacter is made up of over 25 varieties. (brighthub.com)
- A bioinformatics analysis showed that the whole genome sequence of phage Βϕ-R3177 exhibited 62% sequence similarity to that of Acinetobacter phage Βϕ-B1252, but there was no homology seen with other phages. (jcvi.org)
- The genetic background of carbapenem resistance was mostly based on typical Acinetobacter OXA enzymes but also on VIM-2. (mdpi.com)
- Outer membrane protein 33 (Omp33) is an outer membrane porin of Acinetobacter baumannii associated with carbapenem resistance. (nih.gov)
- Many of the characteristics of Acinetobacter ecology, taxonomy, physiology and genetics point to the possibility of exploiting its unique features for future applications. (kenyon.edu)
- Genome sequencing revealed that most were Acinetobacter baumannii , whereas seven represented other Acinetobacter spp. (asm.org)
- Complete Genome Sequence of Acinetobacter indicus Type Strain SGAir0564 Isolated from Tropical Air Collected in Singapore. (kegg.jp)
- Acinetobacter commonly colonizes patients in the intensive care setting. (medscape.com)
- In addition, the study did not evaluate healthcare worker or patient movement and therefore cannot demonstrate transmission of Acinetobacter baumannii to patients as a result of environmental contamination. (elsevier.com)
- The researchers report that 560 community dwelling (mean age ± standard deviation, 74 ± 8.6 years) and 280 nursing home-dwelling (78 ± 9.1 years) patients had Acinetobacter isolated. (infectioncontroltoday.com)
- Previous studies have reported the isolation of Acinetobacter baumannii from the body lice of homeless patients. (ajtmh.org)
- Antimicrobials drugs frequently reported as active against Acinetobacter spp include carbapenems, colistin, ampicillin/sulbactam, amikacin, rifampin and tetracyclines and currently carbapenens are considered the main antimicrobial treatment. (usp.br)
- With MDR Acinetobacter there is often only one drug, colistin, which this organism is sensitive to. (wiredprnews.com)
- Acinetobacter baumannii FolD ligand complexes --potent inhibitors of folate metabolism and a re-evaluation of the structure of LY374571. (biomedsearch.com)