OrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, Agriculture
Acids, CarbocyclicNetropsinInorganic ChemicalsPyrimidine NucleosidesNucleosidesCarbon-Nitrogen Ligases with Glutamine as Amide-N-DonorAdenosylhomocysteinaseCyclizationDistamycinsInosine DiphosphateMalvaceaeThromboxanesRibosemonophosphatesAdenosine Deaminase InhibitorsMolecular StructureCyclopentanesCytidineThromboxane A2StereoisomerismDideoxynucleosidesAntiviral AgentsPolyphloretin PhosphatePalladiumMolecular ConformationInosineAdenosineCarbon-Nitrogen LigasesGuanineAdenosine KinaseAdenineStructure-Activity RelationshipDeoxyguanosineIndicators and ReagentsEpoprostenolNucleotidesOligonucleotidesViral Plaque AssayModels, MolecularKinetics
Acids, Carbocyclic
Carboxylic acids that have a homocyclic ring structure in which all the ring atoms are carbon.
Netropsin
A basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics research.
Inorganic Chemicals
A broad class of substances encompassing all those that do not include carbon and its derivatives as their principal elements. However, carbides, carbonates, cyanides, cyanates, and carbon disulfide are included in this class.
Pyrimidine Nucleosides
Pyrimidines with a RIBOSE attached that can be phosphorylated to PYRIMIDINE NUCLEOTIDES.
Nucleosides
Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor
Enzymes that catalyze the joining of glutamine-derived ammonia and another molecule. The linkage is in the form of a carbon-nitrogen bond. EC 6.3.5.
Adenosylhomocysteinase
An enzyme which catalyzes the catabolism of S-ADENOSYLHOMOCYSTEINE to ADENOSINE and HOMOCYSTEINE. It may play a role in regulating the concentration of intracellular adenosylhomocysteine.
Cyclization
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Distamycins
Oligopeptide antibiotics from Streptomyces distallicus. Their binding to DNA inhibits synthesis of nucleic acids.
Inosine Diphosphate
An inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Malvaceae
The mallow family of the order Malvales, subclass Dilleniidae, class Magnoliopsida. Members include GOSSYPIUM, okra (ABELMOSCHUS), HIBISCUS, and CACAO. The common names of hollyhock and mallow are used for several genera of Malvaceae.
Thromboxanes
Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase.
Ribosemonophosphates
Ribose substituted in the 1-, 3-, or 5-position by a phosphoric acid moiety.
Adenosine Deaminase Inhibitors
Drugs that inhibit ADENOSINE DEAMINASE activity.
Molecular Structure
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Cyclopentanes
A group of alicyclic hydrocarbons with the general formula R-C5H9.
Cytidine
A pyrimidine nucleoside that is composed of the base CYTOSINE linked to the five-carbon sugar D-RIBOSE.
Thromboxane A2
An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
Stereoisomerism
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Dideoxynucleosides
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
Antiviral Agents
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Polyphloretin Phosphate
A polymeric mixture of polyesters of phosphoric acid and phloretin. It blocks some cellular responses to prostaglandins.
Palladium
A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.
Molecular Conformation
The characteristic three-dimensional shape of a molecule.
Inosine
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
Adenosine
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
Carbon-Nitrogen Ligases
Enzymes that catalyze the joining of two molecules by the formation of a carbon-nitrogen bond. EC 6.3.
Guanine
Adenosine Kinase
An enzyme that catalyzes the formation of ADP plus AMP from adenosine plus ATP. It can serve as a salvage mechanism for returning adenosine to nucleic acids. EC 2.7.1.20.
Adenine
A purine base and a fundamental unit of ADENINE NUCLEOTIDES.
Structure-Activity Relationship
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
Deoxyguanosine
A nucleoside consisting of the base guanine and the sugar deoxyribose.
Indicators and Reagents
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Nucleotides
The monomeric units from which DNA or RNA polymers are constructed. They consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
Oligonucleotides
Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)
Viral Plaque Assay
Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.
Models, Molecular
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
Kinetics
The rate dynamics in chemical or physical systems.

Synthesis of telomere-mimic carbocyclic 5'-nor oligodeoxynucleotides. (1/8)

Telomere-mimic S-ODNs have been synthesized and examined their effects on the proliferation of human tumor cell lines by XTT assay. Furthermore, the guanosine derivatives of carbocyclic 5'-nor nucleoside were synthesized.  (+info)

Synthesis of carbocyclic nucleosides as potential antiviral agents. (2/8)

Treatment of 1-[(1'R,2'S,3'S,4'S)-4'-methanesulfonyl-2',3'-O- isopropylidenedioxycyclopentan-1'-yl]-1-H-uracil with LiN3 gave 1-[(1'R,2'S,3'R)-2',3'-O-isopropylidenedioxy-4'- cyclopenten-1'-yl]-1-H-uracil. When KOBut was added instead of LiN3, 1-[(1'R,2'S)-2',3'-O- isopropylidenedioxy-3'-cyclopenten-1'-yl]-1-H-uracil was produced. An analogous treatment of the methanesulfonyl derivative of thymine was also carried out.  (+info)

Synthesis of carbocyclic analogues of 4'-ethynyl- and 4'-cyano-d4T. (3/8)

Synthesis of carbocyclic analogues of 4'-ethynyl and cyano-d4T (4 and 5) was investigated. The ethynyl or cyano group was constructed by conversion of the ester function of key intermediate 13. The carbocyclic unit 12 was prepared from readily available beta-keto ester 6.  (+info)

Carbocyclic analogues of lexitropsin--DNA affinity and endonuclease inhibition. (4/8)

A DNA-binding affinity and the effect on restriction enzymes activity of seven carbocyclic mono- and bis-lexitropsins and two analogues of pentamidine with unsubstituted N-terminal amine group were investigated. DNA association constants (Kapp) show that DNA affinity of mono-compounds is much weaker than netropsin and distamycin. Bis-analogues of netropsin bind DNA more strongly than mono-ligands, but without sequence-selectivity. Only pentamidine derivatives reveal preference to AT-rich sequence. The studied compounds can inhibit catalytical action of endonucleases recognizing sequence of four AT base pairs following one another.  (+info)

Lichen photobionts show tolerance against lichen acids produced by lichen mycobionts. (5/8)

In order to determine the allelopathic nature of lichen acids produced by lichen mycobionts, we compared lichen photobionts with other photosynthetic organisms in terms of inhibition of photosynthetic electron transport around photosystem II (PSII) by representative lichen acids. Whereas at the thylakoid level we found no clear difference in tolerance against lichen acids between lichen photobionts and other species, at the cellular level lichen photobionts showed strong tolerance as compared with other species. These findings suggest the presence of a lichen acid-specific exclusion or detoxification mechanism in lichen photobiont cells.  (+info)

Clinical applications of urinary organic acids. Part 2. Dysbiosis markers. (6/8)

Part 1 of this series focused on urinary organic acids as markers of detoxification; part 2 focuses on dysbiosis markers. Intestinal microbial growth is accompanied by the release of products of their metabolism that may be absorbed and excreted in urine. Several organic acids are known to be specific products of bacterial metabolic action on dietary polyphenols or unassimilated amino acids or carbohydrates. Associated gastrointestinal or neurological symptoms may result from irritation of the intestinal mucosa or systemic distribution of absorbed neurotoxic products. Detection of abnormally elevated levels of these products is a useful diagnostic tool for patients with gastrointestinal or toxicological symptoms. Test profiles of urinary organic acids associated with microbial overgrowth can include benzoate, hippurate, phenylacetate, phenylpropionate, cresol, hydroxybenzoate, hydroxyphenylacetate, hydroxyphenylpropionate and 3,4-dihydroxyphenylpropionate, indican, tricarballylate, D-lactate, and D-arabinitol. Effective treatments for the associated microbial overgrowths may be directed at reducing microbial populations, introducing favorable microbes, and restoring intestinal mucosal integrity.  (+info)

Synthesis, characterization and activity evaluation of matrinic acid derivatives as potential antiproliferative agents. (7/8)

 (+info)

Synthetic analogues of netropsin and distamycin--synthesis of a new pyridine and carbocyclic analogues of the pyrrolecarboxamide antitumour antibiotics. (8/8)

A new series of pyridine-containing analogues III-XXII of distamycin A and netrop sin was investigated by the molecular mechanics technique and molecular modelling. A pyridine analogue of netropsin (VII) is described, the first compound based on molecular studies, and two carbocyclic analogues of distamycin A with an N-terminal chloro- or bromoacetyl group (VIa, VIIa) were synthesized, as well as carbocyclic analogues of netropsin (VIIIb, Xb), potential carriers of alkylating elements. The potential use of VIa, VII, VIIa, VIIIb and Xb as carriers to place into the minor groove of DNA chemical groups capable of modifying DNA, is discussed.  (+info)

Effect of four lichen acids isolated from Hypogymnia physodes on viability of rat thymocytesEffect of four lichen acids isolated from Hypogymnia physodes on viability of rat thymocytes
Four lichen acids, physodalic acid (F1), physodic acid (F2), 3-hydroxyphysodic acid (F3), and isophysodic acid (F4), were isolated from Hypogymnia physodes methanol extract using preparative reversed-phase high performance liquid chromatography and their structures were determined by UV, MS, H-1 NMR and C-13 NMR. This is the first report on the isolation of F4 from H. physodes. Isolated rat thymocytes were cultivated with increasing F1-F4 concentrations (0.1, 1, 10 mu g/well) and proliferative activity, viability, ROS (reactive oxygen species) production and MMP (mitochondrial membrane potential) disturbances were evaluated. Obtained results show significantly decreased thymocytes proliferation was observed when cells were treated with F1 (1 mu g, p LT 0.05; 10 mu g; p LT 0.001), F2 (10 mu g, p LT 0.05) and F3 compound (10 mu g, p LT 0.05). Significantly increased cytotoxicity was detected when cells were incubated with F1 (1 mu g, p LT 0.05; 10 mu g, p LT 0.01), F2 (10 mu ...g, p LT 0.05) and ...
https://cer.ihtm.bg.ac.rs/handle/123456789/1281
Carbocyclic - definition of carbocyclic by The Free DictionaryCarbocyclic - definition of carbocyclic by The Free Dictionary
Define carbocyclic. carbocyclic synonyms, carbocyclic pronunciation, carbocyclic translation, English dictionary definition of carbocyclic. adj. Having a ring composed exclusively of carbon atoms, as benzene. adj containing a closed ring of carbon atoms Adj. 1. carbocyclic - having or relating...
http://www.thefreedictionary.com/carbocyclic
Synthesis and Anti-HIV Activity of Carbocyclic 2,3-Didehydro-2,,3-dideoxy 2,6-Disubstituted Purine Nucleosides<...Synthesis and Anti-HIV Activity of Carbocyclic 2,3-Didehydro-2,,3-dideoxy 2,6-Disubstituted Purine Nucleosides<...
TY - JOUR. T1 - Synthesis and Anti-HIV Activity of Carbocyclic 2,3-Didehydro-2,,3-dideoxy 2,6-Disubstituted Purine Nucleosides. AU - Vince, Robert. AU - Hua, Mei. PY - 1990. Y1 - 1990. N2 - (±)-cis-[4-[(2,5-Diamino-6-chloropyrimidinyl)amino]-2-cyclopentenyl]carbinol (5a) was synthesized from 2-amino-4,6-dichloropyrimidine and cis-4-(hydroxymethyl)cyclopentenylamine (2a) by subsequent preparation of the 5-[(4-chlorophenyl)azo] derivative of the resulting pyrimidine (3a) and reduction of the azo moiety with zinc and acetic acid. The carbocyclic analogue of 2′,3/-didehydro-2′,3′-dideoxy 2-amino-6-chloropurine (6a) and the corresponding 8-azapurine (9a) were prepared from 5a. The carbocyclic 2′,3/-didehydro-2′,3′-dideoxy analogues of guanine (7a) and 2,6-diaminopurine (8a), and 8-azaguanine (10a) and 8-aza-2,6-diaminopurine (11a) were prepared from 6a and 9a, respectively. The corresponding 2′,3′-saturated series of 2-amino-6-substituted-purine carbocyclic nucleosides was prepared ...
https://experts.umn.edu/en/publications/synthesis-and-anti-hiv-activity-of-carbocyclic-23-didehydro-23-di
Plus itPlus it
The introduction of the bioisosteric nitrogen at position 9 of the anthrapyrazole ring structure and the concomitant removal of ring hydroxy substituents cause a number of physicochemical effects that are likely to be relevant in terms of biological activity.. The presence of the aza substituent abolishes self-aggregation phenomena occurring both for MX and LX. This is interesting, because self-aggregated species tend to precipitate from aqueous media causing obvious undesired consequences upon administration (Powis and Kovach, 1983). In addition, the aggregation phenomena subtract part of the drug from the pharmacologically relevant interactions. The reason for lack of aggregation probably rests in the protonation equilibria involving the pyridine nitrogen, which are significant at physiological pH. In fact, although the carbocyclic analogs can easily stack their neutral planar portion one onto the other with the charged side-chains oriented in opposite directions, the same process cannot occur ...
http://molpharm.aspetjournals.org/content/59/1/96
Plus itPlus it
The (+)- and (-)-enantiomers of the carbocyclic analogues of (E)-5-(2-bromovinyl)-2-deoxyuridine (C-BVDU) and 5-iodo-2-deoxyuridine (C-IDU) were synthesized by separate routes. Both the (+)- and (-)-enantiomers of C-BVDU and C-IDU were markedly inhibitory to herpes simplex virus type 1 (HSV-1) replication. (+)-C-BVDU and (+)-C-IDU were as inhibitory to HSV-1 as the racemic (+/-)-C-BVDU and (+/-)-C-IDU, respectively, whereas the (-)-enantiomers were only 10-fold less active. Also, the (+)- and (-)-enantiomers of C-BVDU were equally inhibitory to the growth of murine mammary carcinoma cells transformed by the HSV-1 or HSV-2 thymidine kinase (TK) gene (designated FM3A TK-/HSV-1 TK+ and FM3A TK-/HSV-2 TK+). The (+)- and (-)-enantiomers of C-BVDU and the (+)- and (-)-enantiomers of C-IDU had a remarkably similar affinity for HSV-1 TK [Ki, 0.09 and 0.19 microM for (+)-C-BVDU and (+)-C-IDU and 0.16 and 0.19 microM for (-)-C-BVDU and (-)-C-IDU, respectively]. The inhibition of HSV-1 TK by BVDU, IDU, ...
http://molpharm.aspetjournals.org/content/37/3/395
Acyclic or Carbocyclic CompoundsAcyclic or Carbocyclic Compounds
The use of a mesogenic compound having a terminal end chain comprising carbon, oxygen, or sulphur, which has at least one pendent C¿1-4?alkyl, C¿1-4?alkoxy or a cycloalkyl ring, arranged no more than 6 atoms from the end of the chain e ...
http://www.sumobrain.com/ICL-C07C25-p8.html
Acyclic or Carbocyclic CompoundsAcyclic or Carbocyclic Compounds
What is described is a compound of formula I wherein X is an ethene, or an unsubstitiited or substituted arene or heteroarene; Y is a bond, an ethene, or an unsubstituted or substituted arene or heteroarene; Z is S or O; L is a linear or ...
http://www.sumobrain.com/ICL-C07C271.html
PhotobiontDiversity | Genetic diversity of lichen photobionts and related organisms
After considerable fiddling, Ive finally managed to update the phylogeny and host-association matrix for the most common lichen photobiont, Trebouxia. The methods are similar to those used in my previous post on Nostoc rbcX sequences, to the extent that the same script can used to run both analyses. It was modified to use algal species names rather than host names when analysing Trebouxia, to colour the clades in the tree, and to count the number of times each photobiont lineage has been sampled from each lichen genus. All the steps required for this analysis can be see here. All of the files that were generated are available here.. I had previously built a tree from 1840 ITS sequences and identified lineages corresponding to ten named species and five unnamed species. Since then, there have been a number of important papers that have expanded the known diversity of the group and begun to codify the novel lineages. My current ITS tree (PDF version here) has 2335 sequences and includes 12 named ...
http://photobiontdiversity.org
Heterocyclic compound - Comparison with carbocyclic compounds | chemistry | Britannica.comHeterocyclic compound - Comparison with carbocyclic compounds | chemistry | Britannica.com
Heterocyclic compound - Comparison with carbocyclic compounds: The molecules of organic chemical compounds are built up from a framework or backbone of carbon atoms to which are attached hydrogen (H), oxygen, or other heteroatoms. Carbon atoms have the unique property of being able to link with one another to form chains of atoms. When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound. A typical carbocyclic compound
https://www.britannica.com/science/heterocyclic-compound/Comparison-with-carbocyclic-compounds
Patent US4555396 - Use of pyrylium and thiapyrylium compounds as biological stains - Google PatentsPatent US4555396 - Use of pyrylium and thiapyrylium compounds as biological stains - Google Patents
Disclosed herein is an improvement in a method for distinguishing cells in a biological sample by staining with a dye, wherein the improvement comprises employing as the dye a compound of the formula ##STR1## wherein G is O or S; R1, R3, and R5 are independently selected from the group consisting of hydrogen, alkyl, aryl, aralkyl, amino, styryl, bis(diaryl)vinylene, and ##STR2## wherein R is hydrogen or alkyl; Z represents the elements necessary to complete a basic heterocyclic ring system of the type used in cyanine dyes; n is 0 or 1; R2 is hydrogen or, taken together with either R1 or R3, represents the elements needed to complete an aromatic or a carbocyclic ring system; R4 is hydrogen or, taken together with either R3 or R5, represents the elements needed to complete an aromatic or a carbocyclic ring system; and X- is an anion.
http://www.google.com/patents/US4555396?dq=5,960,411
tricks to solve by komali mam on ellighn diagram
Get Question Papers of Last 10 Years Which class are you in? Billed $59.95 today then every 12 months. To solve this, stand on the glowing spot to the south to make a shining bridge materialize and play the Command Melody. The variables in the algebra can be used to represent the unknown quantities which are coupled in such a way to rewrite the equations. Clickable political map of the World locating all countries of the World with their political boundaries. Class 5 Class 6 Class 7 Class 8 Class 9 Class 10 Class 11 Class 12. Resend OTP. Formal Letters. Other Methods for Carbocyclic Construction: Aspidodispermine … Get one on one guidance from top exam experts as your personal coach to align your preparation strategy. This can be clear by looking at the energy profile diagram for a reaction, R→P. To start using our services, its enough to place a request like I need a writer to do my assignment or Please, write an essay for me. We have a convenient order form, which you can complete ...
http://www.angelvsworld.com/gary-jones-cpdo/tricks-to-solve-by-komali-mam-on-ellighn-diagram-bb14f3
Consorcio de Herbarios de Líquenes en América Latina - Stereocaulon tomentosum
Life habit: lichenized (mutualistic with algal photobionts) thallus: fruticose (fruticous), shrub-like, beard-like thallus: continuous, diffuse, effuse [th] upper surface: grey(ish) [th marginal and upper surface] specific structures: present [th margin] cilia, cilioid structures: absent [th upper surface] isidia, isidioid structures: absent [th upper surface] soredia, soralia, soralioid structures: absent [th] morphol substructures (eg areoles, lobes, branches) upper surface: squamulose ascomata: absent , present ascoma: apothecial, apothecioid hymenial ascoma [mm]: (low) 0.3 (high) 0.6 [ascm] paraphyses/-oids: present asci: lecanoralean [asc] tholus: thickened [asc] tholus amyloidity (iodine reaction): present [asc] tholus amyloidity pattern: with amyloid tube, ring (= Collema-, Micarea-, Porpidia-, Psora-types etc) secondary metabolites: present secondary metabolites: atranorin , norstictic acid , stictic acid primary photobiont: present secondary photobionts (eg in cephalodia): absent , ...
https://lichenportal.org/chlal/taxa/index.php?taxon=55628&clid=1107
CNALH - Fuscidea recensa
Life habit: lichenized (mutualistic with algal photobionts) thallus: crustose (crustaceous) episubstratal unspecified thallus: cracked, fissured, fractured, rimose , compartimentized areolate, squamulate [th] upper surface: grey(ish) , brown(ish) (if pale: fawn, tan; if mid: cinnamon) , white(ish) , brown(ish) grey , red(dish) brown (if pale: orange brown) [th marginal and upper surface] specific structures: present [th margin] cilia, cilioid structures: absent [th upper surface] isidia, isidioid structures: absent [th upper surface] soredia, soralia, soralioid structures: absent , present [th] morphol substructures (eg areoles, lobes, branches) upper surface: smooth, plane , verrucose, warted , bullate [th] medulla amyloidity: absent ascomata: present ascoma: apothecial, apothecioid hymenial ascoma [mm]: (low) 0.5 (high) 0.5 (max) 1.2 ascoma: sessile, superficial [ascm, if apoth] disc, mazaedium: plane, flat, flattened, expanded , subconvex, slightly convex , convex [ascm, if apoth] disc, ...
http://lichenportal.org/portal/taxa/index.php?taxon=56198
40th week of 2009 patent applcation highlights part 6340th week of 2009 patent applcation highlights part 63
Enzyme Inhibitors - Compounds of formula (I), are aurora kinase inhibitors: wherein X is -N-, -CH2-N-, -CH2-CH-, or -CH-; R1 is a radical of formula (IA) wherein Z is -CH2-, -NH-, -0-, -S(O)- -S-, -S(O)2 or a divalent monocyclic carbocyclic or heterocyclic radical having 3-7 ring atoms; Alk is an optionally substituted divalent C1-C6 alkylene radical; A is hydrogen or an optionally substituted monocyclic carbocyclic or heterocyclic ring having 5-7 ring atoms; r, s and t are independently 0 or 1, provided that when A is hydrogen then at least one of r and s is 1; R2 is halogen, -CN, -CF3, -OCH3, or cyclopropyl; and R3 is a radical of formula (IB) wherein Q is hydrogen or an optionally substituted phenyl or monocyclic heterocyclic ring with 5 or 6 ring atoms; Z&It;1, is -S-, -S(O)-, -S(O)2-, -O-, -SO2NH-, -NHSO2-, NHC(═O)NH, -NH(C═S)NH-, Or -N(R4)-wherein R4 is hydrogen, C1-C3 alkyl, cycloalkyl, or benzyl; and Alk&It;1, and Alk&It;2, are, independently, optionally substituted divalent C1-C3 ...
http://www.patentsencyclopedia.com/hgl/10-01-09/10-01-09_63
Icelandic Island MossIcelandic Island Moss
Iceland moss is a type of lichen consisting of a symbiosis of fungi and algae. They form a co-operative of the two species from which both benefit. The fungal part takes care of providing water and minerals, while the algal part forms biological material with the help of photosynthesis. Iceland moss contains a high proportion of water-soluble polysaccharides together with special lichen acids that do not exist anywhere in nature except in lichens. Numerous scientific studies have been carried out on the efficacy of the above materials. The principal results are as follows: Anti-oxidant effects Efficacy against bacteria Efficacy against viruses Efficacy against tumour growth Strengthens the immune system
https://nammi.is/health-beauty/icelandic-health/icelandic-island-moss.html
US4753923A - Thermally-transferred near-infrared absorbing dyes - Google Patents
A dye-donor element for thermal dye transfer comprising a support having on one side thereof a near-infrared absorbing dye comprising a dithiolene-nickel(II) complex dispersed in a polymeric binder, and on the other side thereof a slipping layer comprising a lubricant, the dye having the formula: ##STR1## wherein each R 1 , R 2 , R 3 and R 4 independently represents a substituted or unsubstituted alkyl group having from 1 to about 10 carbon atoms; a substituted or unsubstituted aryl group having from about 6 to about 10 carbon atms; a substituted or unsubstitutted heterocyclic group; or R 1 and R 2 may be combined together with the carbon atoms to which they are attached to form a 5- or 6-membered carbocyclic or heterocyclic ring; or R 3 and R 4 may be combined together with the carbon atoms to which they are attached to form a 5- or 6-membered carbocyclic or heterocyclic ring.
https://patents.google.com/patent/US4753923A/en
Plus itPlus it
Abacavir is a carbocyclic nucleoside analog RTI, which has been shown to be safe and well tolerated by HIV-infected patients (Saag et al., 1998; Hughes et al., 1999; Kumar et al., 1999). Studies have shown that abacavir can enter rat brain and monkey CSF (Daluge et al., 1997); however, this is the first study to examine the mechanisms of abacavir transport into both mammalian brain and CSF. This is important when we consider the complex relationship between drug concentrations in the brain and CSF and also that several anti-HIV drugs are now given in parallel to patients, so abacavir might compete with other drugs for transport into the brain.. Figures 1, 2, 6, and 7 illustrate that intact [14C]abacavir can cross the BBB and confirms a study that found intact abacavir in rat brain 2 h after intraperitoneal administration (Daluge et al., 1997). Figure 6 also confirms that there was little dissociation of the14C label from abacavir during its passage through the cerebral circulation and that ...
http://jpet.aspetjournals.org/content/298/3/947
RCSB PDB - 1YM2: Crystal structure of human beta secretase complexed with NVP-AUR200 Methods Report PageRCSB PDB - 1YM2: Crystal structure of human beta secretase complexed with NVP-AUR200 Methods Report Page
1YM2: Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics
http://www.rcsb.org/pdb/explore/materialsAndMethods.do?structureId=1YM2
Quantification of Age-related Reference Values for Urinary Organic Acids in the Healthy Korean PopulationQuantification of Age-related Reference Values for Urinary Organic Acids in the Healthy Korean Population
PURPOSE: For the accurate diagnosis of organic acidopathies, quantification of urinary organic acid should be done and we should know the normal ranges of each organic acid excreted in the urine. The amount of organic acids excreted in the urine shows wide variability according to ethnic group, diet and age. We have quantified 82 organic acids to make a Korean reference value. METHODS: Organic acid concentrations were quantified with gas chromatography and the individual acids identified with mass spectrometry in urine specimens from members of the healthy Korean population of ages of one day to more than 12 years, subdivided into four age groups : neonatal period(-2 mon), infantile period(-2 year), childhood period(-12 year) and adolescent and adulthood(over 12 years). For isolation of organic acids from urine, we used solvent extraction method with ethylacetate. Derivatization was done with MSTFA(N-methyl-N-trimethylsilylfluoroacetamide). The library and four points quantification curve for ...
https://koreamed.org/article/1052KJP/2001.44.12.1413
Geographic mosaic of symbiont selectivity in a genus of epiphytic cyanolichens - Semantic ScholarGeographic mosaic of symbiont selectivity in a genus of epiphytic cyanolichens - Semantic Scholar
In symbiotic systems, patterns of symbiont diversity and selectivity are crucial for the understanding of fundamental ecological processes such as dispersal and establishment. The lichen genus Nephroma (Peltigerales, Ascomycota) has a nearly cosmopolitan distribution and is thus an attractive model for the study of symbiotic interactions over a wide range of spatial scales. In this study, we analyze the genetic diversity of Nephroma mycobionts and their associated Nostoc photobionts within a global framework. The study is based on Internal Transcribed Spacer (ITS) sequences of fungal symbionts and tRNA(L) (eu) (UAA) intron sequences of cyanobacterial symbionts. The full data set includes 271 Nephroma and 358 Nostoc sequences, with over 150 sequence pairs known to originate from the same lichen thalli. Our results show that all bipartite Nephroma species associate with one group of Nostoc different from Nostoc typically found in tripartite Nephroma species. This conserved association appears to have been
https://www.semanticscholar.org/paper/Geographic-mosaic-of-symbiont-selectivity-in-a-gen-Fedrowitz-Kaasalainen/77426b8e3339686fdb9a3b80951263c0b7c48003
Patent US5206229 - Vitamin d analogues - Google PatentsPatent US5206229 - Vitamin d analogues - Google Patents
##STR1## The present invention relates to compounds of formula (I), in which formula, n is an integer from 1-7; and R1 and R2, which may be the same or different, stand for hydrogen, or lower alkyl (but with the proviso that when n=1, R1 and R2 cannot simultaneously be hydrogen, nor can R1 and R2 simultaneously be an alkyl group independently chosen from methyl, ethyl and normal-propyl, and when n=2, R1 and R2 cannot simultaneously be methyl), or lower cyclo-alkyl, or, taken together with the carbon (starred in formula I) bearing the hydroxyl group, R1 and R2 can form a saturated or unsaturated C3 -C9 carbocyclic ring; and R3 and R4 represent either simultaneously hydrogen, or when taken together constitute a bond, such that a double bond connects carbons 22 and 23; including diastereoisomeric forms (e.g. E or Z configuration of the 22,23-double bond; R or S configuration at the starred carbona atom) of the compounds of formula (I), in pure form or in mixtures. The present compounds find use in both the
http://www.google.com/patents/US5206229?dq=552685
Vinyl Grignard-Mediated Stereoselective Carbocyclization of Lactone Acetals - Research - Aarhus UniversityVinyl Grignard-Mediated Stereoselective Carbocyclization of Lactone Acetals - Research - Aarhus University
A novel Ferrier-type carbocyclization is reported. It involves a carbohydrate-derived lactone acetal synthesized from methyl α-d-glucopyranoside, which upon treatment with excess vinylmagnesium bromide provides a highly substituted carbocyclic product as a single stereoisomer. The yield is greatly increased when N,N,N′,N′-tetramethylethylenediamine is added to the reaction mixture. Optimized reaction conditions have been applied to lactone acetals derived from other carbohydrates. Based on the obtained results, a possible reaction mechanism has been proposed. Furthermore, scalability of the reaction up to 15 g scale and derivatization of the carbocyclic product has been demonstrated, including the formation of a rare trans-bicyclo[4.3.0]nonene scaffold via a ring-closing metathesis. The structure of this and all carbocyclic products were confirmed by X-ray crystallographic analysis. ...
https://pure.au.dk/portal/en/publications/vinyl-grignardmediated-stereoselective-carbocyclization-of-lactone-acetals
Guided meditation in hindi brahma kumaris
Scroggy exenterate Noach and communicate their frequent riots fat and noisily. guillaume musso chomikuj mobi Nigel ruddy ADMIX her mound skill list? Roddie alpha offend his rankle and enisling amphitheater! Ozzie kingdomless barre chortlers guilherme de ockham nominalismo Judaistically lamented. ecological and crenelate Bayard pincers of her corset dawdled unscabbard helplessly. Fazeel sicker and open their debagged Gooneys bristles and hostile itinerate. spongy Hamnet africanized is amply monophthongize telegraph. Interstate Hebert abies their quizzings skillfully. flashing efficient than lip puddles? Andonis zebrine formulising its clusters Gabble with the soul? boastless plagiarises Marve, its very guided meditation in hindi brahma kumaris ita defoliate. and carbocyclic pursued Aram ratten his ball supporter or underestimates impartially. Antoine lozenged mislikes its counterpart implacably. Rog rifle Pupping their graves Hording cheerful? unshoed lead and Edgardo sideswipes his slate or ...
http://betna.tk/guided-meditation-in-hindi-brahma-kumaris
Olympus® GIF-P30 Gastroscope - Misc. Accessory - IEC - Innovative Endoscopy Company, Inc.Olympus® GIF-P30 Gastroscope - Misc. Accessory - IEC - Innovative Endoscopy Company, Inc.
IEC has offered premium surgical equipment, endoscope repair/replacement parts, and services to the international healthcare community for over 15 years.
http://www.endoscopy.md/Items/Search?cwitmid=5481&ctid=0&eq=Olympus-GIF-P30&icid=1219
Carbocycle Construction in Terpene Synthesis | Organic Chemistry | Chemistry | Subjects | WileyCarbocycle Construction in Terpene Synthesis | Organic Chemistry | Chemistry | Subjects | Wiley
This comprehensive and up-to-date discussion of the major ring-forming processes used in synthesis takes its examples from the terpene field. Since terpenes are most representative of carbocyclic compounds found in nature and characterized by intricate assays of ring structures, they are the most attractive and challenging targets for synthesis and a testing ground for defining the limitation of annulation techniques. With over 1200 references, this book constitutes a valuable reference work. It can also serve as supplementary text for senior and graduate level organic chemistry ...
https://www.wiley.com/en-us/Carbocycle+Construction+in+Terpene+Synthesis-p-9780471186793
First-Pass Disposition of (−)-6-Aminocarbovir in Rats. I. Prodrug Activation May Be Limited by Access to Enzyme | Drug...First-Pass Disposition of (−)-6-Aminocarbovir in Rats. I. Prodrug Activation May Be Limited by Access to Enzyme | Drug...
The carbocyclic nucleosides, represented by the prototype molecule, CBV, are novel reverse transcriptase inhibitors with significant activity against HIV (Vince et al., 1988). An analog of CBV, abacavir, is currently in clinical trials (Faletto et al., 1997).. The present work continued the preclinical investigations of another CBV analog, 6AC, and the mechanism of its enhanced systemic delivery of CBV after oral dosing. ADA, the enzyme responsible for the conversion of 6AC to CBV, is localized in the presystemic organs, with the intestine having significantly greater activity than the liver (Ho et al., 1980; Chinsky et al., 1990). For 6AC, the intestine should be the primary organ where most of the first-pass effect takes place after an oral dose. Indeed, the disappearance half-lives of 6AC in the in vitro incubation studies were in accord with the relative tissue distribution of ADA. Homogenate incubations are often used as a means for in vitro prediction of in vivo metabolism. Obviously, ...
https://dmd.aspetjournals.org/content/27/1/113?ijkey=49f7f238a47a44b95d718593e4569a17ed46797f&keytype2=tf_ipsecsha
Preparation of Saturated Ketone Morphinan Compounds by Catalytic Isomerization - Patent applicationPreparation of Saturated Ketone Morphinan Compounds by Catalytic Isomerization - Patent application
11. The process of claim 10, wherein the bis-.THETA.3-bonded ruthenium complex is chosen from:(a) a complex comprising Formula (III): ##STR00012## wherein:R811, R812, R813, R814, R815, and R816 are independently chosen from hydrocarbyl and substituted hydrocarbyl; provided one or more of R811, R812, R813, R814, R815, and R816 may form part of a ring or ring system chosen from carbocyclic, heterocyclic, aryl, heteroaryl, and combinations thereof; provided two or more of R811, R813, R814, and R816 may link together to form a longer chain; andL1 and L2 are independently chosen from anion, hydrocarbyl, and substituted hydrocarbyl; provided L1 and L2 together may form the anion, a hydrocarbyl moiety, or a substituted hydrocarbyl moiety;(b) a complex evaluation comprising Formula (IV): ##STR00013## R611, R812, R813, R814, R815, and R816 are independently chosen from hydrocarbyl and substituted hydrocarbyl; provided one or more of R811, R812, R813, R814, R815, and R816 may form part of a ring or ring ...
http://www.patentsencyclopedia.com/app/20100261904
Patent US4289844 - Photopolymerizable compositions featuring novel co-initiators - Google PatentsPatent US4289844 - Photopolymerizable compositions featuring novel co-initiators - Google Patents
A photopolymerizable composition, element and method of photopolymerizing the composition or element are disclosed wherein the composition comprises an addition polymerizable compound containing ethylenic unsaturation and a co-initiator including a photopolymerization activator and a photosensitizer. In one aspect of the invention, the photosensitizer is selected to be a coumarin having an absorption maximum between about 250 and about 550 nm, and a ##STR1## substituent in the 3-position wherein R1 is alkyl or alkenyl having 1-12 carbon atoms, or a carbocyclic or heterocyclic group having 5-20 nuclear carbon and hetero atoms, the coumarin and the activator being present in an amount sufficient to provide, when the composition is coated, dried and exposed to a medium-pressure mercury light source, a speed which is at least about one-fifth that of the same composition coated, dried and exposed identically except with a co-initiator consisting of Michlers ketone and benzophenone. In another aspect of the
http://www.google.ca/patents/US4289844
Patente US4289844 - Photopolymerizable compositions featuring novel co-initiators - Google PatentesPatente US4289844 - Photopolymerizable compositions featuring novel co-initiators - Google Patentes
A photopolymerizable composition, element and method of photopolymerizing the composition or element are disclosed wherein the composition comprises an addition polymerizable compound containing ethylenic unsaturation and a co-initiator including a photopolymerization activator and a photosensitizer. In one aspect of the invention, the photosensitizer is selected to be a coumarin having an absorption maximum between about 250 and about 550 nm, and a ##STR1## substituent in the 3-position wherein R1 is alkyl or alkenyl having 1-12 carbon atoms, or a carbocyclic or heterocyclic group having 5-20 nuclear carbon and hetero atoms, the coumarin and the activator being present in an amount sufficient to provide, when the composition is coated, dried and exposed to a medium-pressure mercury light source, a speed which is at least about one-fifth that of the same composition coated, dried and exposed identically except with a co-initiator consisting of Michlers ketone and benzophenone. In another aspect of the
http://www.google.es/patents/US4289844?dq=flatulence
Mark L Bosse - Attorney Patent Directory, Page 2
Directory of patents filed by Mark L Bosse (54 patents): Methods for determining peroxidately active substances; Antibiotic formulation and use for bacterial infections; Non nucleoside reverse transcriptase inhibitors; Phosphonomethoxy carbocyclic nucleosides and nucleotides; Aromatic compounds
http://patent.ipexl.com/attorney/mark_l_bosse_2.html
The Dangers of DysbiosisThe Dangers of Dysbiosis
Dysbiosis is a condition that can affect both humans & animals alike. Its an underlying cause of many debilitating diseases. So what the hell is Dysbiosis?
http://www.vitalityandwellness.com.au/health-blog/the-dangers-of-dysbiosis
Katherine Seley-RadtkeKatherine Seley-Radtke
Carbocyclic thymidine analogues for use as potential therapeutic agents. Nucleosides Nucleotides Nucleic Acids. 2009;28(5):633- ... The flexibility of these inhibitors enables binding of the active site as well as amino acid residues outside of the active ... She is also the elected Secretary for the International Society of Nucleosides, Nucleotides & Nucleic Acids (IS3NA), 2019-2023 ... Seley-Radtke, Katherine L; Sunkara, Naresh K (2009-08-11). "Carbocyclic Thymidine Analogues for Use as Potential Therapeutic ...
https://en.wikipedia.org/wiki/Katherine_Seley-Radtke
MiroprofenMiroprofen
Chemically it is a carbocyclic acid and a phenylpropionate. Mikashima H, Goto K (January 1982). "[Inhibitory effect of 2-(4-(2- ... imidazo(1,2-a)pyridyl)phenyl) propionic acid (miroprofen) on platelet aggregation and prostaglandin I2 generation (author's ...
https://en.wikipedia.org/wiki/Miroprofen
GlycomimeticGlycomimetic
Tamiflu is a carbocyclic mimic of the cell-surface carbohydrate sialic acid. Tamiflu is an enzyme inhibitor that blocks the ... either by Coulombic interaction with carboxylate amino acid side-chains in the enzyme active site, or by mimicking positive- ...
https://en.wikipedia.org/wiki/Glycomimetic
Oil additiveOil additive
... the breakdown acids found in used gear oil may include carbocyclic acids, ketones, esters, and nitration and sulfation ... it will have a tendency to collect acids and increase its Total Acid Number (TAN). For example, ... Bases may be used to combat chemical decomposition of the base stock oil in the presence of acids. When oil is subjected to ... Alkaline additives are used to neutralize the acids mentioned previously, and also help prevent the formation of sulfates in a ...
https://en.wikipedia.org/wiki/Oil_additive
Vince lactamVince lactam
Vince, R.; Hua, M. "Synthesis of carbovir and abacavir from a carbocyclic precursor" Current Protocols in nucleic acid ... including carbocyclic puromycin (I), carbocyclic Ara-A (II), carbovir (III) and guanine as well as azaguanine carbocyclic ... Vince lactam has been extensively used for the preparation of various carbocyclic nucleosides with medicinal applications in ... It is named after Robert Vince who has used the structural features of this molecule for the preparation of carbocyclic ...
https://en.wikipedia.org/wiki/Vince_lactam
IndoleIndole
Strong acids such as hydrochloric acid can, however, protonate indole. Indole is primarily protonated at the C3, rather than N1 ... Since the pyrrolic ring is the most reactive portion of indole, electrophilic substitution of the carbocyclic (benzene) ring ... The amino acid tryptophan is an indole derivative and the precursor of the neurotransmitter serotonin. Indole is a solid at ... It is the precursor to indole-3-acetic acid and synthetic tryptophan. The N-H center has a pKa of 21 in DMSO, so that very ...
https://en.wikipedia.org/wiki/Indole
Silver trifluoromethanesulfonateSilver trifluoromethanesulfonate
Part I. Trifluoromethanesulphonic acid", J. Chem. Soc. (in German), pp. 4228-4232, doi:10.1039/JR9540004228 T. Gramstadt, R.N. ... salts form carbocyclic rings", J. Org. Chem. (in German), vol. 41, no. 17, pp. 2882-2885, doi:10.1021/jo00879a019 Stang, Peter ... Perfluoroalkanesulphonic acids", J. Chem. Soc. (in German), pp. 173-180, doi:10.1039/JR9560000173 G.M. Whitesides, F.D. ... An early preparation method starts from the barium salt of trifluoromethanesulfonic acid (TfOH), from which the free TfOH is ...
https://en.wikipedia.org/wiki/Silver_trifluoromethanesulfonate
Raymond C. StevensRaymond C. Stevens
... and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity J Am Chem Soc 119: 681-90; M. ... The human Lysophosphatidic acid receptor 1 (LPAR1), the human angiotensin II receptor type 1 (AT1R), human P2Y receptor 1 (P2Y1 ... Crystal structure of human lysophosphatidic acid receptor 1 Cell 161: 1633-1643 H. Zhang, H. Unal, C. Gati, G.W. Han, W. Liu, N ... Structure-activity relationships of carbocyclic influenza neuraminidase inhibitors Bioorg Med Chem Lett 7: 1837-1842; C. U. Kim ...
https://en.wikipedia.org/wiki/Raymond_C._Stevens
DHQDHQ
... may refer to: 3-Dehydroquinic acid, the first carbocyclic intermediate of the shikimate pathway Digital Humanities ...
https://en.wikipedia.org/wiki/DHQ
Outline of thoughtOutline of thought
Carbocyclic sugar L-DOPA - Chemical compound Lecithin - Generic term for amphiphilic substances of plant and animal origin ... Amino acid Vasopressin - Mammalian hormone released from the pituitary gland Vinpocetine Vitamin B3, also known as Nicotinic ... Type of α-amino acid Piracetam - Cerebral activators (Nootropil) Pramiracetam Pyritinol (Enerbol) Rhodiola rosea - Species of ... acid - Class of chemically related vitamers Vitamin B5 Vitamin B6 - Class of chemically related vitamins Vitamin B12 - Vitamin ...
https://en.wikipedia.org/wiki/Outline_of_thought
TestolactoneTestolactone
... , also known as 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid δ-lactone, is a synthetic 18-oxasteroid ... with a six-membered lactone ring in place of the five-membered carbocyclic D-ring. Testolactone was first approved for medical ...
https://en.wikipedia.org/wiki/Testolactone
Carbocyclic nucleosideCarbocyclic nucleoside
Nucleic Acids. 19 (3): 651-690. doi:10.1080/15257770008035015. PMID 10843500. S2CID 43360920. Wang J; Rawal RK; Chu CK (August ... The fluorocarbocyclic nucleoside carbocyclic 2′-ara-fluoro-guanosine was reported in 1988 as the first example of a carbocyclic ... Antiviral Carbocyclic Purine nucleosides (-)Carbovir Abacavir Entecavir Carbocyclic 2′-ara-fluoro-guanosine Entecavir, a ... There are two approaches used in the synthesis of carbocyclic nucleosides. Linear approaches to chiral carbocyclic nucleosides ...
https://en.wikipedia.org/wiki/Carbocyclic_nucleoside
Aminoshikimic acidAminoshikimic acid
It is characterized by multiple stereogenic centers and functional groups arrayed around a six-membered carbocyclic ring. ... As with shikimic acid, aminoshikimic acid is an attractive candidate for use as the core scaffold for synthesis of ... Aminoshikimic acid is also an alternative to shikimic acid as a starting material for the synthesis of neuraminidase inhibitors ... Aminoshikimic acid is an intriguing alternative to shikimic acid as a starting material for the synthesis of neuraminidase ...
https://en.wikipedia.org/wiki/Aminoshikimic_acid
Vulpinic acidVulpinic acid
Crout, D.H.G. (2012). "The Biosynthesis of Carbocyclic Compounds". In Lloyd, D. (ed.). Carbocyclic Chemistry. Vol. One. ... Vulpinic acid is derived biosynthetically by esterification from pulvinic acid; pulvinate itself derives from the aromatic ... both of which derive from aromatic amino acids such as phenylalanine via secondary metabolism. The roles of vulpinic acid are ... Vulpinic acid is a natural product first found in and important in the symbiosis underlying the biology of lichens. It is a ...
https://en.wikipedia.org/wiki/Vulpinic_acid
Caffeic acidCaffeic acid
"Chemical Land". Caffeic Acid as Carbocyclic Carboxylic Acid. (Chemical articles with multiple compound IDs, Multiple chemicals ... Umbellic acid (2,4-dihydroxycinnamic acid) 2,3-Dihydroxycinnamic acid 2,5-Dihydroxycinnamic acid Gould, Kevin S.; Markham, ... Caffeate O-methyltransferase is an enzyme responsible for the transformation of caffeic acid into ferulic acid. Caffeic acid ... 4-dicarboxylic acid). Caffeic acid can also be polymerized using the horseradish peroxidase/H2O2 oxidizing system. Caffeic acid ...
https://en.wikipedia.org/wiki/Caffeic_acid
3-Dehydroquinic acid3-Dehydroquinic acid
... (DHQ) is the first carbocyclic intermediate of the shikimate pathway. It is created from 3- ... 3-Dehydroquinic acid undergoes five further enzymatic steps in the remainder of the shikimate pathway to chorismic acid, a ... 3-Dehydroquinate goes through beta oxidation, similar to fatty acids. Then, this compound (6-oxo-3-dehydro-quinate) is ... Morrow, Gary W. (2016). "The Shikimate Pathway: Biosynthesis of Phenolic Products from Shikimic Acid". Oxford University Press ...
https://en.wikipedia.org/wiki/3-Dehydroquinic_acid
Cyclopropane fatty acidCyclopropane fatty acid
"Carbocyclic fatty acids in plants: Biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of ... Cyclopropene fatty acids are even rarer than CPAs. The best-known examples are malvalic acid and sterculic acid. Sterculic acid ... Cyclopropane fatty acids (CPA) are a subgroup of fatty acids that contain a cyclopropane group. Although they are usually rare ... which catalyzes the biodesaturation of stearic acid to oleic acid. At least one review indicates that CPFA are carcinogenic, co ...
https://en.wikipedia.org/wiki/Cyclopropane_fatty_acid
Methylene cyclopropyl acetic acidMethylene cyclopropyl acetic acid
Dihydrosterculic acid is the major carbocyclic fatty acid in the seed oils of Litchi chinensis. It is a cyclopropane fatty acid ... Biochem J 1962;82:385-9. PMC 1243468 "Natural alicyclic fatty acids, section:Cyclopropane and Cyclopropene Fatty Acids from ... Methylene cyclopropyl acetic acid (MCPA) is a compound found in lychee (Litchi chinensis) seeds. It is also a metabolite in ... Methylene cyclopropyl acetic acid (MCPA) is found in lychee seeds and also a toxic metabolite in mammalian digestion after ...
https://en.wikipedia.org/wiki/Methylene_cyclopropyl_acetic_acid
Intramolecular reactions of diazocarbonyl compoundsIntramolecular reactions of diazocarbonyl compounds
5) In the presence of a catalytic amount of acid, diazomethyl ketone substrates containing a pendant double bond or aryl group ... 7) Transannular insertions, which form fused carbocyclic products, have also been observed. Yields are often low for these ... 11) A solution of the olefinic acid (0.499 g, 2.25 mmol) dissolved in benzene (20 ml, freshly distilled from calcium hydride) ... Very often, the diazocarbonyl compound is prepared and immediately used via treatment of the corresponding acid chloride with ...
https://en.wikipedia.org/wiki/Intramolecular_reactions_of_diazocarbonyl_compounds
AromaticityAromaticity
Hofmann, A. W. (1855). "On Insolinic Acid". Proceedings of the Royal Society. 8: 1-3. doi:10.1098/rspl.1856.0002. Rocke, A. J ... Aromaticity also occurs in compounds that are not carbocyclic or heterocyclic; inorganic six-membered-ring compounds analogous ... The four aromatic amino acids histidine, phenylalanine, tryptophan, and tyrosine each serve as one of the 20 basic building- ... Examples include trinitrotoluene (TNT), acetylsalicylic acid (aspirin), paracetamol, and the nucleotides of DNA. Aromatic ...
https://en.wikipedia.org/wiki/Aromaticity
ArtemisininArtemisinin
Dihydroartemisinic acid then undergoes photo-oxidation to produce dihydroartemisinic acid hydroperoxide. Ring expansion by the ... and desilylation steps performed on this mono-carbocyclic intermediate, including a final singlet oxygen-utilizing ... The synthesized artemisinic acid can then be transported out, purified and chemically converted into artemisinin that they ... A three-step oxidation of amorpha-4,11-diene gives the resulting artemisinic acid. The UC Berkeley method was augmented using ...
https://en.wikipedia.org/wiki/Artemisinin
Ferrier carbocyclizationFerrier carbocyclization
A carbocyclic ring closure of a hex-5-enopyranoside derivative". J. Chem. Soc., Perkin Trans. 1: 1455-1458. doi:10.1039/ ... worked in the same reaction as a milder version of the Lewis acid, i-Bu3Al, which goes through a similar transition state ... Das, SK; Mallet, J-M; Sinaÿ, P (1997). "Novel Carbocyclic Ring Closure of Hex-5-enopyranosides". Angew. Chem. Int. Ed. 36 (5): ... Barton, DHR; Camara, J; Dalko, P; Géro, SD; Quiclet-Sire, B; Stütz, P (1989). "Synthesis of biologically active carbocyclic ...
https://en.wikipedia.org/wiki/Ferrier_carbocyclization
CyclononatetraeneCyclononatetraene
E 17b, 4th Edition Supplement: Carbocyclic Three-Membered Ring Compounds, Cyclopropanes: Synthesis. Goettingen: Georg Thieme ... showing that cyclononatetraene is a weaker acid than cyclopentadiene. Cyclononatetraenyl cation is an 8π system. Its ...
https://en.wikipedia.org/wiki/Cyclononatetraene
Discovery and development of cyclooxygenase 2 inhibitorsDiscovery and development of cyclooxygenase 2 inhibitors
The substituted phenyl group at the top of the channel interacts with the side-chains of amino acid residues through ... that is fused in this stilbene system has been extensively manipulated to include every imaginable heterocyclic and carbocyclic ... Celecoxib is metabolized primarily by CYP2C9 isoenzyme to carboxylic acid and also by non-CYP-dependent glucuronidation to ... These compounds differ greatly from NSAIDs that are arylalkonic acid analogs. Encouraged by the "concept testing" experiments ...
https://en.wikipedia.org/wiki/Discovery_and_development_of_cyclooxygenase_2_inhibitors
BenzotriazoleBenzotriazole
A synthesis of the BTA involves the reaction of o-phenylenediamine, sodium nitrite, and acetic acid. The conversion proceeds ... methodology is not only limited to heterocyclization but was also successful for polynuclear hydrocarbons of small carbocyclic ... Biphenylene and benzyne can be conveniently prepared from benzotriazole by N-amination with hydroxylamine-O-sulfonic acid. The ... the BTA can lose a proton to act as a weak acid (pKa = 8.2) or accept a proton using the lone pair electrons located on its ...
https://en.wikipedia.org/wiki/Benzotriazole
InositolInositol
Phytic acid also occurs in cereals with high bran content. Phytate is, however, not directly bioavailable to humans in the diet ... Inositol, or more precisely myo-inositol, is a carbocyclic sugar that is abundant in the brain and other mammalian tissues; it ... "Phytic acid". www.phytochemicals.info. Archived from the original on 2017-08-06. Retrieved 2017-10-02. Reynolds, J. E. F. (1993 ... "Phytic acid". www.phytochemicals.info. Archived from the original on 7 March 2018. Retrieved 2018-05-02. Klopfenstein, T. J.; ...
https://en.wikipedia.org/wiki/Inositol
Organolithium reagentOrganolithium reagent
4-Biphenylacetic Acid and 4-Biphenylcarboxylic Acid/Triphenylmethane as Indicators in the Titration of Lithium Alkyls. Study of ... Another application that takes advantage of this reactivity is the formation of carbocyclic and heterocyclic compounds by ... Lithium enolate formation can be generalized as an acid-base reaction, in which the relatively acidic proton α to the carbonyl ... Organolithium reagents are also better than Grignard reagents in their ability to react with carboxylic acids to form ketones. ...
https://en.wikipedia.org/wiki/Organolithium_reagent
Cofactor F430Cofactor F430
... having a γ-lactam ring E and a keto-containing carbocyclic ring F. It is the only natural tetrapyrrole containing nickel, an ... out a 6-electron and 7-proton reduction of the ring system in a reaction EC 6.3.3.7 generating the 15,173-seco-F430-173-acid ( ...
https://en.wikipedia.org/wiki/Cofactor_F430
Heterocyclic compoundHeterocyclic compound
Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related ... either carbocyclic or heterocyclic, have a variety of common and systematic names. For example, with the benzo-fused ... Some noteworthy developments: 1818: Brugnatelli isolates alloxan from uric acid 1832: Dobereiner produces furfural (a furan) by ... treating starch with sulfuric acid 1834: Runge obtains pyrrole ("fiery oil") by dry distillation of bones 1906: Friedlander ...
https://en.wikipedia.org/wiki/Heterocyclic_compound
Danheiser annulationDanheiser annulation
... in the presence of a Lewis Acid to give a trialkylsilylcyclopentene in a regiocontrolled annulation. R. L. Danheiser; D. J. ... New Annulation Approaches to Five and Six-Membered Carbocyclic Compounds". Tetrahedron Letters. 26 (21): 2513. doi:10.1016/ ...
https://en.wikipedia.org/wiki/Danheiser_annulation
PiroxicamPiroxicam
Tiaprofenic acid (tiaprofenate). *Vedaprofen; Anthranilic acids (fenamic acids): Etofenamic acid (etofenamate). *Floctafenic ... Agonists: Carbocyclic thromboxane A2. *I-BOP. *Thromboxane A2. *U-46619 ...
https://en.wikipedia.org/wiki/Piroxicam
LornoxicamLornoxicam
Tiaprofenic acid (tiaprofenate). *Vedaprofen; Anthranilic acids (fenamic acids): Etofenamic acid (etofenamate). *Floctafenic ... Agonists: Carbocyclic thromboxane A2. *I-BOP. *Thromboxane A2. *U-46619 ...
https://en.wikipedia.org/wiki/Lornoxicam
Intramolecular Heck reactionIntramolecular Heck reaction
The reaction may be used to produce carbocyclic or heterocyclic organic compounds with a variety of ring sizes. Chiral ... scopadulcic acid. A 6-exo cyclization sets the quaternary center and provides a neopentyl σ-palladium intermediate, which ...
https://en.wikipedia.org/wiki/Intramolecular_Heck_reaction
KevlarKevlar
"Wholly aromatic carbocyclic polycarbonamide fiber having orientation... - US 3819587 A - IP.com". ip.com. Tatsuya Hongū, Glyn O ... Kevlar production is expensive because of the difficulties arising from using concentrated sulfuric acid, needed to keep the ... and terephthaloyl chloride in a condensation reaction yielding hydrochloric acid as a byproduct. The result has liquid- ...
https://en.wikipedia.org/wiki/Kevlar
Stieglitz rearrangementStieglitz rearrangement
... by which carboxylic acids can be transformed into amines through the addition of hydrazoic acid under acidic aqueous conditions ... "Carbocyclic Ring Construction via an Intramolecular Diels-Alder Reaction of an in-Situ Generated, Heteroatom-Stabilized Allyl ... In a Beckmann rearrangement, the acid catalyzed carbon to nitrogen migration takes place on the oxime to yield a nitrilium ion ... When subjecting the azide to a Brønsted acid, the protonation of the azide activates the basal nitrogen and lowers the bond ...
https://en.wikipedia.org/wiki/Stieglitz_rearrangement
PropellanePropellane
It was first synthesized in 2018 using a general strategy for the synthesis of carbocyclic propellanes from 1,3- ... and spontaneously reacts with acetic acid to form a methylenecyclobutane ester. Several synthetic procedures are established ... "Asymmetric Synthesis of Carbocyclic Propellanes". Org. Lett. 19 (9): 2310-2313. doi:10.1021/acs.orglett.7b00836. PMID 28445060 ...
https://en.wikipedia.org/wiki/Propellane
Bicyclic moleculeBicyclic molecule
A bicyclic compound can be carbocyclic (all of the ring atoms are carbons), or heterocyclic (the rings' atoms consist of at ... B. Smith, "Organic Chemistry: An Acid-Base Approach", Taylor & Francis, 2011, Page 302, https://books.google.nl/books?id= ...
https://en.wikipedia.org/wiki/Bicyclic_molecule
Robert Vince (scientist)Robert Vince (scientist)
Vince continued his work on antiviral drug candidates at the University of Minnesota, where he went on to develop carbocyclic ... Nucleotides and Nucleic Acids, in 2010. The same year, Minnesota Inventor's Congress inducted him into Minnesota Inventors Hall ... Nucleotides and Nucleic Acids ACS Medicinal Chemistry Hall of Fame (Articles with short description, Short description matches ... Nucleotides and Nucleic Acids April 2010: Received Honorary Doctorate of Science Degree from SUNY Buffalo September 2009: ...
https://en.wikipedia.org/wiki/Robert_Vince_(scientist)
Carbocyclic nucleoside - WikipediaCarbocyclic nucleoside - Wikipedia
Nucleic Acids. 19 (3): 651-690. doi:10.1080/15257770008035015. PMID 10843500. S2CID 43360920. Wang J; Rawal RK; Chu CK (August ... The fluorocarbocyclic nucleoside carbocyclic 2′-ara-fluoro-guanosine was reported in 1988 as the first example of a carbocyclic ... Antiviral Carbocyclic Purine nucleosides (-)Carbovir Abacavir Entecavir Carbocyclic 2′-ara-fluoro-guanosine Entecavir, a ... There are two approaches used in the synthesis of carbocyclic nucleosides. Linear approaches to chiral carbocyclic nucleosides ...
https://en.wikipedia.org/wiki/Carbocyclic_nucleoside
Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)
Categories: Acids, Carbocyclic Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted ...
https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Acids,+Carbocyclic&parentid=5358&catid=1810
US4284796A - Preparation of 4-acyloxy-2-methyl-crotonaldehydes - Google Patents
... with water in the presence of a carboxylic acid of the formula R--COOH III. ... C07C-ACYCLIC OR CARBOCYCLIC COMPOUNDS * C07C67/00-Preparation of carboxylic acid esters ... 3. The process of claim 1, wherein the carboxylic acid of the formula III is acetic acid. ... 150000001732 carboxylic acid derivatives Chemical class 0.000 claims abstract description 11 * 238000000034 method Methods ...
https://patents.google.com/patent/US4284796A/en
Fenoprofen | Harvard Catalyst Profiles | Harvard CatalystFenoprofen | Harvard Catalyst Profiles | Harvard Catalyst
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Phenylpropionates [D02.241.223.701]. *Fenoprofen [D02.241. ...
https://connects.catalyst.harvard.edu/Profiles/display/Concept/Fenoprofen
CN106661030 Improved forms of PI3K delta selective inhibitor for use in pharmaceutical formulationsCN106661030 Improved forms of PI3K delta selective inhibitor for use in pharmaceutical formulations
The present invention relates to solid state forms of a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta ... ACYCLIC OR CARBOCYCLIC COMPOUNDS. 309. Sulfonic acids; Halides, esters, or anhydrides thereof. 01. Sulfonic acids. 28. having ... EN) The present invention relates to solid state forms of a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta ...
https://patentscope.wipo.int/search/en/detail.jsf?docId=CN198373700&_fid=LT336583000
Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)
Categories: Acids, Carbocyclic Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted ...
https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Acids,%20Carbocyclic&parentid=5358&catid=1810
3 Or 4 Amino Acid Residues In The Peptide Chain Patents and Patent Applications (Class 514/21.9) - Justia Patents Search3 Or 4 Amino Acid Residues In The Peptide Chain Patents and Patent Applications (Class 514/21.9) - Justia Patents Search
Search for 3 Or 4 Amino Acid Residues In The Peptide Chain Patents and Patent Applications (Class 514/21.9) Filed with the ... Abstract: This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically ... Containing Doai Patents 3 Or 4 Amino Acid Residues In The Peptide Chain Patents (Class 514/21.9) 3 Or 4 Amino Acid Residues In ... Carboxylic acid-containing small molecules can be used in the methods and compositions disclosed herein, for example, sulindac ...
https://patents.justia.com/patents-by-us-classification/514/21.9
PT3149000 IMPROVED FORMS OF A PI3K DELTA SELECTIVE INHIBITOR FOR USE IN PHARMACEUTICAL FORMULATIONSPT3149000 IMPROVED FORMS OF A PI3K DELTA SELECTIVE INHIBITOR FOR USE IN PHARMACEUTICAL FORMULATIONS
ACYCLIC OR CARBOCYCLIC COMPOUNDS. 309. Sulfonic acids; Halides, esters, or anhydrides thereof. 01. Sulfonic acids. 28. having ...
https://patentscope.wipo.int/search/en/detail.jsf?docId=PT332455800&_fid=KR201449585
Widespread Oseltamivir Resistance in Influenza A Viruses (H1N1), South Africa - Volume 14, Number 11-November 2008 - Emerging...
... synthesis and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. J Am Chem Soc. 1997 ...
https://wwwnc.cdc.gov/eid/article/14/11/08-0958_article
LIPID MAPS® Lipidomics Gateway
Alepramic acid. 3-(2-cyclopenten-1-yl)-propanoic acid. Fatty Acids and Conjugates [FA01]. Carbocyclic fatty acids [FA0114]. ... 2-octynoic acid. 2-octynoic acid. Fatty Acids and Conjugates [FA01]. Unsaturated fatty acids [FA0103]. 140.08. C8H12O2. ... 7-octynoic acid. 7-octynoic acid. Fatty Acids and Conjugates [FA01]. Unsaturated fatty acids [FA0103]. 140.08. C8H12O2. ... 5,7-octadienoic acid. 5,7-octadienoic acid. Fatty Acids and Conjugates [FA01]. Unsaturated fatty acids [FA0103]. 140.08. C8H12O ...
https://www.lipidmaps.org/data/chemdb_lm_text_ontology.php?ABBREV=FA%208:2
Flux profiling of photosynthetic carbon metabolism in intact plants | Nature ProtocolsFlux profiling of photosynthetic carbon metabolism in intact plants | Nature Protocols
Carbocyclic fatty acids in plants: biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of ... Ong, S.-E. & Mann, M. A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC). Nat. Protoc. 1, ... Lipps, S.H. & Beevers, H. Compartmentation of organic acids in corn roots I. differential labeling of 2 malate pools. Plant ... Tomato aromatic amino acid decarboxylases participate in synthesis of the flavor volatiles 2-phenylethanol and 2- ...
https://www.nature.com/articles/nprot.2014.115?error=cookies_not_supported&code=afda19dc-1b1e-4c13-89dc-3a0ffda02fc5
Gallic Acid | Profiles RNS
Acids, Carbocyclic [D02.241.223]. *Benzoates [D02.241.223.100]. *Hydroxybenzoates [D02.241.223.100.300]. *Gallic Acid [D02.241. ... "Gallic Acid" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Gallic Acid" by people in this website by year, and whether " ... Suppression of TNF-? induced NF?B activity by gallic acid and its semi-synthetic esters: possible role in cancer ...
https://profiles.umassmed.edu/display/111641
1-NAPHTHOIC ACID (1-NAPHTHALENECARBOXYLIC ACID)1-NAPHTHOIC ACID (1-NAPHTHALENECARBOXYLIC ACID)
alpha-Naphthylcarboxylic acid; Naphthalene-alpha-carboxylic acid; alpha-Naphthoic acid; 1-Maythic acid; Isonaphthoic acid; ... CARBOCYCLIC CARBOXYLIC ACIDS PHYSICAL AND CHEMICAL PROPERTIES. PHYSICAL STATE. white to off white crystals. ... 1-Naphthoic acid is used as an intermediate for the synthesis of pharmaceuticals, photochemicals, plant growth hormones, dyes ...
http://www.chemicalland21.com/specialtychem/finechem/1-NAPHTHOIC%20ACID.htm
Chemistry Tree - Thimmaiah GovindarajuChemistry Tree - Thimmaiah Govindaraju
Conformationally preorganized carbocyclic and backbone extended pyrrolidine peptide nucleic acids: chemical synthesis and ...
https://academictree.org/chemistry/peopleinfo.php?pid=285211
β-PEPTIDES CYCLOBUTANIQUES - TEL - Thèses en ligneβ-PEPTIDES CYCLOBUTANIQUES - TEL - Thèses en ligne
The bibliographical section, divided into two parts, describes the synthesis deβ-amino acids carbocyclic then the different ... Abstract : The synthesis of β-amino acids, structural analogues of?-Amino acids, is an issue essential in the development of ... amino acids). As a result, the conformational preference of β-amino acids will induce the appearance of a three-dimensional ... A lot of work has been conducted on the behavior of β-peptide (sequence of β-amino acids) as well as peptides mixed (mixed β- ...
https://tel.archives-ouvertes.fr/tel-00731023
Parabens | Harvard Catalyst Profiles | Harvard CatalystParabens | Harvard Catalyst Profiles | Harvard Catalyst
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Benzoic Acids [D02.241.223.100]. *Hydroxybenzoic Acids [D02.241 ... Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents ...
https://connects.catalyst.harvard.edu/Profiles/display/Concept/Parabens
Recent applications of barbituric acid in multicomponent reactions - RSC Advances (RSC Publishing)Recent applications of barbituric acid in multicomponent reactions - RSC Advances (RSC Publishing)
There is a wide range of multicomponent reactions that include barbituric acid as starting material. This article aims to revie ... Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbocyclic compounds and ... Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbocyclic compounds and ... Recent applications of barbituric acid in multicomponent reactions G. Mohammadi Ziarani, F. Aleali and N. Lashgari, RSC Adv., ...
https://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C6RA09874F
Properties of oligonucleotide with phenyl-substituted carbocyclic nucleoside analogs for the formation of duplex and triplex...
In: Nucleosides, Nucleotides and Nucleic Acids, Vol. 31, No. 12, 01.12.2012, p. 841-860.. Research output: Contribution to ... Nasr T, Taniguchi Y, Takaki T, Okamura H, Sasaki S. Properties of oligonucleotide with phenyl-substituted carbocyclic ... Therefore, the skeleton of the phenyl-substituted carbocyclic nucleoside analog 10 may be a platform for the formation of ... Therefore, the skeleton of the phenyl-substituted carbocyclic nucleoside analog 10 may be a platform for the formation of ...
https://kyushu-u.pure.elsevier.com/en/publications/properties-of-oligonucleotide-with-phenyl-substituted-carbocyclic
Dibutyl Phthalate | Colorado PROFILES
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Phthalic Acids [D02.241.223.805]. *Dibutyl Phthalate [D02.241. ...
https://profiles.ucdenver.edu/display/203006
Synthesis and Antiviral Activity of Carbocyclic Analogues of Xylofuranosides of 2-Amino-6-substituted-purines and 2-Amino-6...Synthesis and Antiviral Activity of Carbocyclic Analogues of Xylofuranosides of 2-Amino-6-substituted-purines and 2-Amino-6...
Dive into the research topics of Synthesis and Antiviral Activity of Carbocyclic Analogues of Xylofuranosides of 2-Amino-6- ... Synthesis and Antiviral Activity of Carbocyclic Analogues of Xylofuranosides of 2-Amino-6-substituted-purines and 2-Amino-6- ...
https://experts.umn.edu/en/publications/synthesis-and-antiviral-activity-of-carbocyclic-analogues-of-xylo/fingerprints/
Mefenamic acidMefenamic acid
... is a member of the anthranilic acid derivatives (or fenamate) class of NSAID drugs, and is used ... Agonists: Carbocyclic thromboxane A2. *I-BOP. *Thromboxane A2. *U-46619 ... Mefenamic acid is recommended to be taken with food.[7]. Known mild side effects of mefenamic acid include headaches, ... Valerian constituents (e.g., isovaleric acid, isovaleramide, valerenic acid, valerenol). *Unsorted benzodiazepine site positive ...
https://zims-en.kiwix.campusafrica.gos.orange.com/wikipedia_en_all_nopic/A/Mefenamic_acid
o-Phthalaldehyde | Colorado PROFILES
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Phthalic Acids [D02.241.223.805]. *o-Phthalaldehyde [D02.241. ...
https://profiles.ucdenver.edu/display/217970
DeCS Ingl s
D02.241 Carboxylic Acids .. D02.241.223 Acids, Carbocyclic .. D02.241.223.701 Phenylpropionates .. D02.241.223.701.350 ... Cromoglycic Acid .. Cromolyn .. FPL-670 .. Intal .. Lomudal .. Nalcrom .. Nasalcrom .. Opticrom .. Vicrom .. Acid, Cromoglicic ... Acid, Cromoglycic .. Cromoglycate, Disodium .. Cromoglycate, Sodium .. FPL 670 .. FPL670 .. Sodium Cromoglycate .. Disodium ...
http://trigramas.bireme.br/cgi-bin/mx/[email protected]?collection=DeCSi&lang=e&minsim=0.30&maxrel=10&text=Nalcrom
Dinitolmide | Profiles RNS
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Benzoates [D02.241.223.100]. *Benzamides [D02.241.223.100.100] ...
https://profiles.rush.edu/display/10290
Metrizoate | Profiles RNS
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Benzoic Acids [D02.241.223.100]. *Benzoic Acid [D02.241.223.100 ...
https://profiles.uchicago.edu/profiles/display/22949
Methylphenidate | Profiles RNS
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Phenylacetates [D02.241.223.601]. *Methylphenidate [D02.241. ...
https://profiles.jefferson.edu/display/14171
Nitrobenzoates | Profiles RNS
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Benzoates [D02.241.223.100]. *Nitrobenzoates [D02.241.223.100. ... Benzoic acid or benzoic acid esters substituted with one or more nitro groups. ... Use of a microplate reader in an assay of glutathione reductase using 5,5-dithiobis(2-nitrobenzoic acid). Anal Biochem. 1989 ...
https://researchers.childrensmercy.org/display/11874
Iopamidol | Profiles RNS
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Benzoates [D02.241.223.100]. *Iodobenzoates [D02.241.223.100. ...
https://profiles.ouhsc.edu/display/10101
Phenylpyruvic Acids | Profiles RNS
Below are MeSH descriptors whose meaning is related to "Phenylpyruvic Acids".. *Acids, Carbocyclic ... "Phenylpyruvic Acids" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Phenylpyruvic Acids" by people in this website by year, and ... A group of compounds that are derivatives of phenylpyruvic acid which has the general formula C6H5CH2COCOOH, and is a ...
https://researchers.childrensmercy.org/display/12930
British Library EThOS: The α-alkylation of ketones using hydrogen borrowing catalysisBritish Library EThOS: The α-alkylation of ketones using hydrogen borrowing catalysis
... and seven-membered carbocyclic rings. The optimisation of the reactions conditions is described followed by a systematic ... followed by trapping with several nucleophiles led to the formation of carboxylic acid derivatives. The final part of the ... investigation into the diastereoselectivity observed in the formation of the carbocyclic rings. With the formation of ...
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.780421
CompoundsSynthesisDerivativesRing carbocyclic nucleosidesNucleosidesFattyAnaloguesLactic acidAmino acidMolecularMoietyEstersRacemicMethionineSkeletons2019EnzymesSolventSubstituentsInositolIntramolecularCycloadditionCOMPOUNDSEstersCarboxylicThioctic AcidAmino AcidsLipidsNucleic AcidsFatty acidsEnantioselectiveSubstancesMeSHAnalogueAldehydeConjugatesPentanoicAlkylLewisCarbonClassProprietaryAmine
Compounds14
  • A large number of novel carbocyclic nucleosides of pyrimidines and purines have been prepared, and many of these compounds are endowed with interesting biological activities. (wikipedia.org)
  • 1-Naphthoic acid is used as an intermediate for the synthesis of pharmaceuticals, photochemicals, plant growth hormones, dyes and other organic compounds. (chemicalland21.com)
  • The bibliographical section, divided into two parts, describes the synthesis deβ-amino acids carbocyclic then the different types of secondary structures of peptides derived from β-amino acid compounds. (archives-ouvertes.fr)
  • Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbocyclic compounds and considered as an important building block in organic synthesis. (rsc.org)
  • This article aims to review the chemistry of barbituric acids employed in the design and synthesis of different types of compounds during the period from 2011 to 2015. (rsc.org)
  • A group of compounds that are derivatives of phenylpyruvic acid which has the general formula C6H5CH2COCOOH, and is a metabolite of phenylalanine. (childrensmercy.org)
  • 18. Yu Bai, Weijie Tao, Jun Ren and Zhongwen Wang* "Lewis Acid Catalyzed Intramolecular [4+2] and [3+2] Cross-Cycloaddition of Alkynylcyclopropane Ketones with Carbonyl Compounds and Imines" Angew. (nankai.edu.cn)
  • In organic chemistry, Dicarboxylic Acids are a subclass of organic compounds , in the carboxylic acid class in the organic acids superclass , containing exactly two carboxylic acid groups. (wellnessadvantage.com)
  • Dicarboxylic Acid compounds are acyclic acid compounds, that contains two carboxylic acid groups and have the formula HO 2 C-R-CO 2 H, where R may be either an aromatic or aliphatic functional group. (wellnessadvantage.com)
  • Metal-catalyzed hydrofunctionalization reactions of alkynes, i.e., the addition of Y-H units (Y = heteroatom or carbon) across the carbon-carbon triple bond, have attracted enormous attention for decades since they allow the straightforward and atom-economic access to a wide variety of functionalized olefins and, in its intramolecular version, to relevant heterocyclic and carbocyclic compounds. (sciencegate.app)
  • Recently, Brønsted acids such as HNTf2 and HOTf have been shown to be powerful activators that promote catalytic alkyne alkoxylation/Claisen rearrangement, leading to the concise and flexible synthesis of valuable compounds with high efficiency and atom economy. (sciencegate.app)
  • They are known as carbocyclic or alicyclic compounds. (msvgo.com)
  • They can be further subdivided into two categories: carbocyclic compounds and heterocyclic compounds. (tutorcity.sg)
  • These secondary compounds are primarily classified on the basis of their carbocyclic skeletons into pseudoguainolides, guaianalides, germanocranolides, eudesmanolides, heliangolides and hyptocretenolides etc (Figure 1). (dosingpdf.com)
Synthesis12
  • There are two approaches used in the synthesis of carbocyclic nucleosides. (wikipedia.org)
  • 1966: First described synthesis of the racemic (±) carbocyclic analogue of adenosine. (wikipedia.org)
  • 1988: Review of Glaxo's synthesis of fluorocarbocyclic nucleosides 1988: (±)-Carbovir first reported with potent anti-HIV activity and low cytotoxicity 1992: First comprehensive review of the synthesis of chiral carbocyclic nucleosides. (wikipedia.org)
  • The synthesis of β-amino acids, structural analogues of? (archives-ouvertes.fr)
  • This work on the synthesis of optically pure ACBC and the behavior of β-peptides cyclobutaniques completes the picture of carbocyclic β-peptides. (archives-ouvertes.fr)
  • To address carbocyclic fatty acid synthesis in plants, a cDNA library was constructed from developing seeds during the period of maximum oil deposition. (typeset.io)
  • Morandi, B. Nickel‐Catalyzed Cascade Annulation for the Rapid Synthesis of Carbocyclic Nitriles. (mpg.de)
  • Morandi, B. CO- and HCl-Free Synthesis of Acid Chlorides from Unsaturated Hydrocarbons Via Shuttle Catalysis. (mpg.de)
  • The key carbocyclic allylic alcohol intermediate 5-methoxymethylcyclopent-2-enol was synthesized via a six step synthesis in racemic form from the ethylene-acetal of 2-methoxymethylcyclopentanone but attempts at deprotection of the methyl ether proved unsuccessful. (shu.ac.uk)
  • This chapter discusses the methods of formation, synthesis, properties and reactions of anthracenes and its homologs such as alkyl-, aryl-anthracenes, aminoanthracenes, hydroxyanthracenes (anthrols), anthracenecarboxylic acids and their functional derivatives. (bath.ac.uk)
  • Brijesh M. Sharma, Mahesh Yadav, Rajesh G. Gonnade And and Pradeep Kumar*, Unified Approach to Fused and Spirocyclic Oxindoles through Lewis-Acid-Promoted Opening of Spiroepoxyoxindoles with Allylsilanes: Application to the Formal Synthesis of (±)-Physovenine, Eur. (ncl.res.in)
  • The AB plus D strategy for tetracycline synthesis by C-ring construction is shown to be robust across a range of different carbocyclic and heterocyclic D-ring precursors, proceeding reliably and with a high degree of stereochemical control. (health-articles.net)
Derivatives7
  • This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. (justia.com)
  • Mefenamic acid is a member of the anthranilic acid derivatives (or fenamate) class of NSAID drugs, and is used to treat mild to moderate pain, including menstrual pain , and is sometimes used to prevent migraines associated with menstruation. (orange.com)
  • Like other members of the anthranilic acid derivatives (or fenamate) class of NSAID drugs, it inhibits both isoforms of COX and prevents formation of prostaglandins . (orange.com)
  • Scientists led by Claude Winder from Parke-Davis invented mefenamic acid in 1961, along with fellow members of the class of anthranilic acid derivatives , flufenamic acid in 1963 and meclofenamate sodium in 1964. (orange.com)
  • Derivatisation of the resulting β-branched products through bromine-initiated release of the aryl group, followed by trapping with several nucleophiles led to the formation of carboxylic acid derivatives. (bl.uk)
  • Hydroxylated benzoic acid derivatives that contain mercury. (nih.gov)
  • Etheno (and ethano) derivatives of nucleic acid bases have an extra 5-membered ring attached. (biomedcentral.com)
Ring carbocyclic nucleosides1
  • The 5-membered ring carbocyclic nucleosides aristeromycin, the analog of adenosine, and neplanocin A, the cyclopentene analog of aristeromycin, have been isolated from natural sources. (wikipedia.org)
Nucleosides5
  • Carbocyclic nucleosides (also referred to as carbanucleosides) are nucleoside analogues in which a methylene group has replaced the oxygen atom of the furanose ring. (wikipedia.org)
  • The two guanine antiviral carbocyclic nucleosides, the anti-HIV agent abacavir and the anti-hepatitis B agent entecavir, are reverse-transcriptase inhibitors. (wikipedia.org)
  • Antiviral Carbocyclic Purine nucleosides (-)Carbovir Abacavir Entecavir Carbocyclic 2′-ara-fluoro-guanosine Entecavir, a guanosine analog, was reported in 1997 as a potent and selective inhibitor for the hepatitis B virus, and approved by the FDA in March 2005 for oral treatment of hepatitis B infection. (wikipedia.org)
  • Linear approaches to chiral carbocyclic nucleosides 2 rely on the construction of the heterocyclic base onto a suitable protected chiral cyclopentylamine (1 → 2). (wikipedia.org)
  • This amide was easily acid hydrolysed to the amine hydrochloride which was subsequently used to synthesize a variety of purine based nucleosides. (shu.ac.uk)
Fatty11
  • A cDNA library was constructed from developing seeds during the period of maximum oil deposition and a CPA-FA synthase was identified from S. foetida, and the pathway in higher plants that produce carbocyclic fatty acids was defined as by transfer of C1 units, most likely from S-adenosylmethionine to oleate. (typeset.io)
  • Fatty acids containing three-member carbocyclic rings are found in bacteria and plants. (typeset.io)
  • Bacteria synthesize cyclopropane fatty acids (CPA-FAs) only by the addition of a methylene group from S-adenosylmethionine to the cis-double bond of monoenoic phospholipid-bound fatty acids. (typeset.io)
  • In plants CPA-FAs are usually minor components with cyclopropene fatty acids (CPE-FAs) more abundant. (typeset.io)
  • Functional analysis of the isolated full-length cDNA was conducted in tobacco suspension cells where its expression resulted in the accumulation of up to 6.2% dihydrosterculate of total fatty acids. (typeset.io)
  • Together, a CPA-FA synthase was identified from S. foetida, and the pathway in higher plants that produce carbocyclic fatty acids was defined as by transfer of C1 units, most likely from S-adenosylmethionine to oleate. (typeset.io)
  • Toporosides A and B, Cyclopentenyl-Containing ω-Glycosylated Fatty Acid Amides, and Toporosides C and D from the Northwestern Pacific Marine Sponge Stelodoryx toporoki . (lipidmaps.org)
  • Structurally, arachidonic acid is a 20-carbon fatty acid, present as a component of the phospholipids of the cell membranes. (assignology.com)
  • In lipid science , Dicarboxylic Acids [FA0117] are a subclass in the Fatty acyl lipid class [FA] . (wellnessadvantage.com)
  • Sodium or potassium salts of fatty acids are gone through decarboxylation. (msvgo.com)
  • Feller, S.E. Gawrisch, G. and MacKerell, Jr., A.D. Polyunsaturated !Fatty Acids in Lipid Bilayers: Intrinsic and Environmental !Contributions to Their Unique Physical Properties. (charmm.org)
Analogues1
  • Three phencyclidine (PCP) analogues possessing a highly rigid carbocyclic structure and an attached piperidine ring which is free to rotate were synthesized. (thevespiary.org)
Lactic acid1
  • Poor laurus nobilis good lauryl alcohol good lauryl glucoside good lauryl lactate mixture of lauryl alcohol and lactic acid that functions as a skin-conditioning agent and… Dd-tv is the only air-based broadcasting corporation in india that provides television service coverage across india and its neighboring nations, including pakistan, nepal and even bangladeshi. (filomena-formaro.de)
Amino acid9
  • In the laboratory, we work on the β-amino acid cyclobutane as a building block of molecular structures developed with β-peptides. (archives-ouvertes.fr)
  • Work has been conducted on the β-amino acid cyclic 6, 5 and 4-membered ring. (archives-ouvertes.fr)
  • However, no work has been described on the trans-cyclobutane β-amino acid "trans-ACBC. (archives-ouvertes.fr)
  • The residual amino acid side chain (from methionine) is esterified and acetylated to form wybutosine (Fig. 4 ). (biomedcentral.com)
  • Amino acid Isomil 1 showed a lower relative content of β-glycosylated (39.1%) and a higher relative content of acetylglycosilated (28.4%) isoflavones in relation to the three above-mentioned samples. (faah-signal.com)
  • Workout enthusiasts have long been educated on L-arginine, an amino acid that's responsible for boosting nitric oxide (NO) levels in the body. (priceplow.com)
  • The "M" in MIC Injection, is an essential amino acid, which means that it is not synthesized in humans. (zelkeninstitute.com)
  • an amino acid that helps prevent fatigue and works as an anti-oxidant to neutralize toxins in the body. (b12injectionsmiami.com)
  • Evolution of amino acid 215 in HIV-1 reverse transcriptase in response to intermittent drug selection. (hivfrenchresistance.org)
Molecular1
  • In organic chemistry , Glutaric Acid (Glutarate or Glutaric Oxoacid) is an organic compound the molecular formula (C 3 H 6 (COOH) 2 ). (wellnessadvantage.com)
Moiety1
  • In the convergent approach the intact heterocyclic base is coupled directly to a suitably protected functionalised carbocyclic moiety (3 → 2). (wikipedia.org)
Esters4
  • induced NF?B activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. (umassmed.edu)
  • Benzoic acid or benzoic acid esters substituted with one or more nitro groups. (childrensmercy.org)
  • Acid value was decreased by esterification process using sulfuric acid anhydrous (H2SO4) as a catalyst and alkaline (NaOH) catalyst transesterification was carried out for the conversion of crude oil to methyl esters. (typeset.io)
  • The salts or esters of salicylic acids, or salicylate esters of an organic acid. (bvsalud.org)
Racemic1
  • Abacavir, was developed from racemic (±)-carbovir which was reported in 1988 by Robert Vince as the first carbocyclic nucleoside analogue to show potent activity against HIV with low cytotoxicity. (wikipedia.org)
Methionine2
  • In addition, the dihydrosterculate was specifically labeled by [methyl-14C]methionine and by [14C]oleic acid in the transgenic tobacco cells. (typeset.io)
  • One of the sulfur-containing amino acids (along with cysteine and cystine), methionine is important (essential) to many bodily functions and must be directly consumed through supplementation or methionine-containing proteins. (zelkeninstitute.com)
Skeletons1
  • 16. Siyang Xing, Yan Li, Zhen Li, Chang Liu, Jun Ren and Zhongwen Wang* "Lewis Acid-Catalyzed Intramolecular Cross [3+2] Cycloaddition of Donor-Acceptor Cyclopropanes with Carbonyls: A General Strategy for Construction of Bridge-Acetal[n.2.1] Skeletons" Angew. (nankai.edu.cn)
20191
  • [14] In the Philippines, 1 tablet of 500 mg generic mefenamic acid cost PHP25.00 (or the equivalent of US$0.50) as of September 2, 2019. (orange.com)
Enzymes2
  • En plus de cette fascinante particularité, les β-peptides et les peptides mixtes ont montré une grande stabilité vis-à-vis des enzymes digestives. (archives-ouvertes.fr)
  • The lipoocygenase pathway comprises of lipooxygenases enzymes that act on arachidonic acid and result in the formation of 5-HPETE and 15-HPETE respectively. (assignology.com)
Solvent1
  • The effects of solvent, time, temperature and the use of different Lewis acids were studied, showing dramatic effects for solvent and Lewis acid. (unav.edu)
Substituents1
  • There are many ways to produce heterocyclic rings, but the most common processes involve the use of precursors to synthesize the desired molecule, modification of an existing heterocyclic or carbocyclic ring, or modifying the substituents on an existing heterocycle. (cabb-chemicals.com)
Inositol2
  • Also known as myo-inositol, inositol is best described as a carbocyclic polyol, which forms the basis for many signaling and secondary messenger molecules. (zelkeninstitute.com)
  • Inositol, or more precisely myo-inositol, is a carbocyclic sugar that is abundant in brain and other mammalian tissues, mediates cell signal transduction in response to a variety of hormones, neurotransmitters and growth factors and participates in osmoregulation. (nanochemia.ir)
Intramolecular3
  • 4. Bao Hu, Siyang Xing, Zhongwen Wang* "Lewis Acid Catalyzed Ring-Opening Intramolecular Friedel-Crafts Alkylation of Methylenecyclopropane 1,1-Diesters" Org. (nankai.edu.cn)
  • 13. Bao Hu, Jun Ren, Zhongwen Wang* "Lewis acid-catalyzed nucleophilic ring-opening/intramolecular Conia-ene reactions of methylenecyclopropane 1,1-diesters with propargyl alcohols" Tetrahedron 2011, 67(04), 763-768. (nankai.edu.cn)
  • Recent advances on the Brønsted acid catalyzed alkyne alkoxylation/Claisen rearrangement are introduced in this Account, in which both intramolecular and intermolecular tandem reactions are discussed. (sciencegate.app)
Cycloaddition1
  • vital reactions equivalent to carbo- and hetero-Diels-Alder, carbocyclic, cyclopropanation and 1,3-dipolar cycloaddition reactions are mentioned. (kkt.as)
COMPOUNDS2
  • New compounds identified in this work included twelve benzoic and cinnamic acid derivatives. (nih.gov)
  • Specifically, asymmetric catalysis using chiral Lewis acids provides a crucial tool in the enantioselective synthesis of chiral organic compounds. (duq.edu)
Esters4
  • In addition to two isomeric (E)-caffeoyl ethyl tartrates, the glucose esters of (E)-cinnamic, (E)-p-coumaric, and (E)-ferulic acid, as well as the 4-O-glucosides of (E)- and (Z)-ferulic acid, have been identified for the first time in Riesling wine. (nih.gov)
  • Moreover, two ethyl esters, i.e., ethyl protocatechuate and ethyl gallate, as well as the glucose ester of vanillic acid, were newly detected in Riesling wine. (nih.gov)
  • Polyphosphoric acids, 2-[alkyl-1-oxo-2-propen-1-yl)oxy]ethyl esters, compds. (toxplanet.com)
  • Facile Transformation of α,β-Unsaturated Carboxylic Acids to Alkenylboronic Esters via Rhodium-catalyzed Decarbonylative Borylation of α,β-Unsaturated Thioesters. (riken.jp)
Carboxylic2
  • Carboxylic acids that have open-chain molecular structures as opposed to ring-shaped structures. (umassmed.edu)
  • Rhodium-Catalyzed Decarbonylative Borylation of Aromatic Thioesters for Facile Diversification of Aromatic Carboxylic Acids. (riken.jp)
Thioctic Acid2
  • This graph shows the total number of publications written about "Thioctic Acid" by people in this website by year, and whether "Thioctic Acid" was a major or minor topic of these publications. (ouhsc.edu)
  • Below are the most recent publications written about "Thioctic Acid" by people in Profiles. (ouhsc.edu)
Amino Acids2
  • This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. (pandudesign.com)
  • SAFE & UNIQUE INGREDIENTS: Amberen is a proprietary blend of succinates, amino acids, vitamin E, and minerals. (thesmartchoose.com)
Lipids1
  • Straight-chain fatty acids and cyclic fatty acids in lipids during maturation of the seeds. (lipidmaps.org)
Nucleic Acids2
  • Inspired by the cytochrome P450 catalyzed transformation of furan into a reactive enal species, we recently introduced a furan-oxidation-based methodology for cross-linking of nucleic acids. (ugent.be)
  • These furan-modified nucleic acids can form interstrand cross-links upon selective furan oxidation with N-bromosuccinimide. (ugent.be)
Fatty acids1
Enantioselective3
  • Uncovering the differential forces between the ground and transition structures with chiral Lewis acids is a perquisite step towards the creation of more effective enantioselective catalysts. (duq.edu)
  • Specifically, bis(oxazoline) copper(II) complexes operate as enantioselective Lewis acid catalysts for carbocyclic and hetero Diels-Alder reactions. (duq.edu)
  • The functionalization of indoles in the carbocyclic ring has been achieved via organocatalytic enantioselective Friedel-Crafts benzhydrylation of hydroxyindoles with in situ generated ortho-quinomethanes in oil-water biphases, allowing an efficient access to varied diarylindolylmethanes with a wide substrate scope. (bvsalud.org)
Substances1
  • Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic pandudesign.com: Peter A. Jacobi. (pandudesign.com)
MeSH2
  • Abscisic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • Acids, Acyclic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Analogue3
  • Incorporation of the carbocyclic analogue of (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate into a synthetic DNA. (neb.com)
  • The replacement of the ring oxygen with a methylene group to generate a carbocyclic analogue leads to enhancement of its chemical stability. (unimi.it)
  • Herein, we report conjugation of carbocyclic analogue monomer, dimer, and trimer to the protein carrier CRM197. (unimi.it)
Aldehyde2
  • 1-azirine 3-position acetic acid adduct aldehyde alkaloids alkene alkyl amine anhydride aromatic azetidine aziridine azirine base basic benzene benzene ring benzo benzofuran bond Bromination carbon atoms carbonyl CH3 CH3 Chem Chemical Reactions Chemistry chloride condensation COOC2H5 COOCH3 COOH cyclization cycloaddition derivatives diaziridine 3/5(6). (pandudesign.com)
  • Dicarboxylic acids in which one of the carboxyl groups (-COOH) has been replaced by an aldehyde group (-CHO). (bvsalud.org)
Conjugates2
  • Conjugates with longer carbocyclic oligomers and/or precise acetylation patterns could further increase the induced immune response to a level comparable with those of commercially available anti-meningococcal glycoconjugate vaccines. (unimi.it)
  • These building blocks offer a new, facile and shorter access route to bile acid-peptide conjugates on solid-phase with emphasis on heterodipodal conjugates with defined spatial arrangements. (ugent.be)
Pentanoic1
  • An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. (ouhsc.edu)
Alkyl1
  • The homologs of phenanthrene include the alkyl-phenanthrenes, aminophenanthrenes or phenanthrylamines, hydroxyphenanthrenes or phenanthrols, formyl- and acyl-phenanthrenes, phenanthrenecarboxylic acids, phenanthrene quinones and biphenanthryls. (bath.ac.uk)
Lewis6
  • Yang and co-workers also tried lower-temperature conditions in the presence of various Lewis acids but these were also unsuccessful. (nature.com)
  • My Ph.D. dissertation describes three different external influences on pericyclic reactions: (1) ionic liquids, (2) Lewis acids and (3) bis(oxazoline)-Cu(II) complexes. (duq.edu)
  • 2) Lewis acids are known to influence strongly the rate, regio, endo/exo, diastereofacial and enantio selectivities of the Diels-Alder reaction. (duq.edu)
  • Our efforts focus upon a novel combination of two specific intermolecular interactions between boron Lewis acids and Diels-Alder transition structures. (duq.edu)
  • Principles of Chemical Reactivity on the Diels-Alder Reaction in Ionic Liquids and Lewis Acid Catalysis using Large-Scale Computations (Doctoral dissertation, Duquesne University). (duq.edu)
  • This is the first example of metal-catalyzed asymmetric transformations of the in situ generated p-QMs, avoiding using pre-synthesized p-QMs requiring bulky 2,6-substitutions and highlighting a new dual catalytic activation with the chiral bis(oxazoline)-metal complex acting as a normal Lewis acid to activate the ß-ketoesters and a source of Brønsted acid responsible for generating the p-QMs in situ. (bvsalud.org)
Carbon1
  • The carbon-metal bond of the ferrocene structure was a new concept of p-bonding of a carbocyclic ring to a metal atom. (subjecto.com)
Class1
  • lt;p>Polydiphenylenephthalide (PDP) belongs to the class of carbocyclic organic electroactive polymers, which exhibit electric conductive properties when an external electric field and/or mechanical stress is applied. (beilstein-archives.org)
Proprietary1
  • Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. (drugbank.com)
Amine1
  • Kevlar is synthesized in solution from the monomers 1,4- phenylene -di amine ( para -phenylenediamine ) and terephthaloyl chloride in a condensation reaction yielding hydrochloric acid as a byproduct. (knowpia.com)
Fenoprofen | Harvard Catalyst Profiles | Harvard Catalyst
Fenoprofen | Harvard Catalyst Profiles | Harvard Catalyst (connects.catalyst.harvard.edu)
Advanced Search Results - Public Health Image Library(PHIL)
Advanced Search Results - Public Health Image Library(PHIL) (phil.cdc.gov)
LIPID MAPS® Lipidomics Gateway
LIPID MAPS® Lipidomics Gateway (lipidmaps.org)
Flux profiling of photosynthetic carbon metabolism in intact plants | Nature Protocols
Flux profiling of photosynthetic carbon metabolism in intact plants | Nature Protocols (nature.com)
Recent applications of barbituric acid in multicomponent reactions - RSC Advances (RSC Publishing)
Recent applications of barbituric acid in multicomponent reactions - RSC Advances (RSC Publishing) (pubs.rsc.org)
Details - Public Health Image Library(PHIL)
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Dinitolmide | Profiles RNS
Dinitolmide | Profiles RNS (profiles.rush.edu)
British Library EThOS: The α-alkylation of ketones using hydrogen borrowing catalysis
British Library EThOS: The α-alkylation of ketones using hydrogen borrowing catalysis (ethos.bl.uk)
Sterculia foetida | 166 Publications | 2532 Citations | Top Authors | Related Topics
Sterculia foetida | 166 Publications | 2532 Citations | Top Authors | Related Topics (typeset.io)
Benzoylformic Acid: Uses, Interactions, Mechanism of Action | DrugBank Online
Benzoylformic Acid: Uses, Interactions, Mechanism of Action | DrugBank Online (go.drugbank.com)
NViroMune - COMBINATION COMPOSITIONS FOR THE TREATMENT OF INFECTIONS
NViroMune - COMBINATION COMPOSITIONS FOR THE TREATMENT OF INFECTIONS (nviromune.com)
SFB 234 - University of Regensburg Publication Server
SFB 234 - University of Regensburg Publication Server (epub.uni-regensburg.de)
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MeSH Browser (meshb-prev.nlm.nih.gov)