Acids, Carbocyclic
Netropsin
Inorganic Chemicals
Pyrimidine Nucleosides
Nucleosides
Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor
Adenosylhomocysteinase
Cyclization
Distamycins
Inosine Diphosphate
Malvaceae
Thromboxanes
Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase.
Molecular Structure
Cytidine
Thromboxane A2
Stereoisomerism
Dideoxynucleosides
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
Antiviral Agents
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Polyphloretin Phosphate
Palladium
Inosine
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
Adenosine
Carbon-Nitrogen Ligases
Adenosine Kinase
Structure-Activity Relationship
Indicators and Reagents
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Epoprostenol
Nucleotides
Oligonucleotides
Viral Plaque Assay
Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.
Models, Molecular
Synthesis of telomere-mimic carbocyclic 5'-nor oligodeoxynucleotides. (1/8)
Telomere-mimic S-ODNs have been synthesized and examined their effects on the proliferation of human tumor cell lines by XTT assay. Furthermore, the guanosine derivatives of carbocyclic 5'-nor nucleoside were synthesized. (+info)Synthesis of carbocyclic nucleosides as potential antiviral agents. (2/8)
Treatment of 1-[(1'R,2'S,3'S,4'S)-4'-methanesulfonyl-2',3'-O- isopropylidenedioxycyclopentan-1'-yl]-1-H-uracil with LiN3 gave 1-[(1'R,2'S,3'R)-2',3'-O-isopropylidenedioxy-4'- cyclopenten-1'-yl]-1-H-uracil. When KOBut was added instead of LiN3, 1-[(1'R,2'S)-2',3'-O- isopropylidenedioxy-3'-cyclopenten-1'-yl]-1-H-uracil was produced. An analogous treatment of the methanesulfonyl derivative of thymine was also carried out. (+info)Synthesis of carbocyclic analogues of 4'-ethynyl- and 4'-cyano-d4T. (3/8)
Synthesis of carbocyclic analogues of 4'-ethynyl and cyano-d4T (4 and 5) was investigated. The ethynyl or cyano group was constructed by conversion of the ester function of key intermediate 13. The carbocyclic unit 12 was prepared from readily available beta-keto ester 6. (+info)Carbocyclic analogues of lexitropsin--DNA affinity and endonuclease inhibition. (4/8)
A DNA-binding affinity and the effect on restriction enzymes activity of seven carbocyclic mono- and bis-lexitropsins and two analogues of pentamidine with unsubstituted N-terminal amine group were investigated. DNA association constants (Kapp) show that DNA affinity of mono-compounds is much weaker than netropsin and distamycin. Bis-analogues of netropsin bind DNA more strongly than mono-ligands, but without sequence-selectivity. Only pentamidine derivatives reveal preference to AT-rich sequence. The studied compounds can inhibit catalytical action of endonucleases recognizing sequence of four AT base pairs following one another. (+info)Lichen photobionts show tolerance against lichen acids produced by lichen mycobionts. (5/8)
In order to determine the allelopathic nature of lichen acids produced by lichen mycobionts, we compared lichen photobionts with other photosynthetic organisms in terms of inhibition of photosynthetic electron transport around photosystem II (PSII) by representative lichen acids. Whereas at the thylakoid level we found no clear difference in tolerance against lichen acids between lichen photobionts and other species, at the cellular level lichen photobionts showed strong tolerance as compared with other species. These findings suggest the presence of a lichen acid-specific exclusion or detoxification mechanism in lichen photobiont cells. (+info)Clinical applications of urinary organic acids. Part 2. Dysbiosis markers. (6/8)
Part 1 of this series focused on urinary organic acids as markers of detoxification; part 2 focuses on dysbiosis markers. Intestinal microbial growth is accompanied by the release of products of their metabolism that may be absorbed and excreted in urine. Several organic acids are known to be specific products of bacterial metabolic action on dietary polyphenols or unassimilated amino acids or carbohydrates. Associated gastrointestinal or neurological symptoms may result from irritation of the intestinal mucosa or systemic distribution of absorbed neurotoxic products. Detection of abnormally elevated levels of these products is a useful diagnostic tool for patients with gastrointestinal or toxicological symptoms. Test profiles of urinary organic acids associated with microbial overgrowth can include benzoate, hippurate, phenylacetate, phenylpropionate, cresol, hydroxybenzoate, hydroxyphenylacetate, hydroxyphenylpropionate and 3,4-dihydroxyphenylpropionate, indican, tricarballylate, D-lactate, and D-arabinitol. Effective treatments for the associated microbial overgrowths may be directed at reducing microbial populations, introducing favorable microbes, and restoring intestinal mucosal integrity. (+info)Synthesis, characterization and activity evaluation of matrinic acid derivatives as potential antiproliferative agents. (7/8)
(+info)Synthetic analogues of netropsin and distamycin--synthesis of a new pyridine and carbocyclic analogues of the pyrrolecarboxamide antitumour antibiotics. (8/8)
A new series of pyridine-containing analogues III-XXII of distamycin A and netrop sin was investigated by the molecular mechanics technique and molecular modelling. A pyridine analogue of netropsin (VII) is described, the first compound based on molecular studies, and two carbocyclic analogues of distamycin A with an N-terminal chloro- or bromoacetyl group (VIa, VIIa) were synthesized, as well as carbocyclic analogues of netropsin (VIIIb, Xb), potential carriers of alkylating elements. The potential use of VIa, VII, VIIa, VIIIb and Xb as carriers to place into the minor groove of DNA chemical groups capable of modifying DNA, is discussed. (+info)
Effect of four lichen acids isolated from Hypogymnia physodes on viability of rat thymocytes
Carbocyclic - definition of carbocyclic by The Free Dictionary
Synthesis and Anti-HIV Activity of Carbocyclic 2,3-Didehydro-2,,3-dideoxy 2,6-Disubstituted Purine Nucleosides<...
Plus it
Plus it
Acyclic or Carbocyclic Compounds
Acyclic or Carbocyclic Compounds
PhotobiontDiversity | Genetic diversity of lichen photobionts and related organisms
Heterocyclic compound - Comparison with carbocyclic compounds | chemistry | Britannica.com
Patent US4555396 - Use of pyrylium and thiapyrylium compounds as biological stains - Google Patents
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Consorcio de Herbarios de Líquenes en América Latina - Stereocaulon tomentosum
CNALH - Fuscidea recensa
40th week of 2009 patent applcation highlights part 63
Icelandic Island Moss
US4753923A - Thermally-transferred near-infrared absorbing dyes - Google Patents
Plus it
RCSB PDB
- 1YM2: Crystal structure of human beta secretase complexed with NVP-AUR200 Methods Report Page
Quantification of Age-related Reference Values for Urinary Organic Acids in the Healthy Korean Population
Geographic mosaic of symbiont selectivity in a genus of epiphytic cyanolichens - Semantic Scholar
Patent US5206229 - Vitamin d analogues - Google Patents
Vinyl Grignard-Mediated Stereoselective Carbocyclization of Lactone Acetals - Research - Aarhus University
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Olympus® GIF-P30 Gastroscope - Misc. Accessory - IEC - Innovative Endoscopy Company, Inc.
Carbocycle Construction in Terpene Synthesis | Organic Chemistry | Chemistry | Subjects | Wiley
First-Pass Disposition of (−)-6-Aminocarbovir in Rats. I. Prodrug Activation May Be Limited by Access to Enzyme | Drug...
Preparation of Saturated Ketone Morphinan Compounds by Catalytic Isomerization - Patent application
Patent US4289844 - Photopolymerizable compositions featuring novel co-initiators - Google Patents
Patente US4289844 - Photopolymerizable compositions featuring novel co-initiators - Google Patentes
Mark L Bosse - Attorney Patent Directory, Page 2
The Dangers of Dysbiosis
Katherine Seley-Radtke
Carbocyclic thymidine analogues for use as potential therapeutic agents. Nucleosides Nucleotides Nucleic Acids. 2009;28(5):633- ... The flexibility of these inhibitors enables binding of the active site as well as amino acid residues outside of the active ... She is also the elected Secretary for the International Society of Nucleosides, Nucleotides & Nucleic Acids (IS3NA), 2019-2023 ... Seley-Radtke, Katherine L; Sunkara, Naresh K (2009-08-11). "Carbocyclic Thymidine Analogues for Use as Potential Therapeutic ...
Miroprofen
Chemically it is a carbocyclic acid and a phenylpropionate. Mikashima H, Goto K (January 1982). "[Inhibitory effect of 2-(4-(2- ... imidazo(1,2-a)pyridyl)phenyl) propionic acid (miroprofen) on platelet aggregation and prostaglandin I2 generation (author's ...
Glycomimetic
Tamiflu is a carbocyclic mimic of the cell-surface carbohydrate sialic acid. Tamiflu is an enzyme inhibitor that blocks the ... either by Coulombic interaction with carboxylate amino acid side-chains in the enzyme active site, or by mimicking positive- ...
Oil additive
... the breakdown acids found in used gear oil may include carbocyclic acids, ketones, esters, and nitration and sulfation ... it will have a tendency to collect acids and increase its Total Acid Number (TAN). For example, ... Bases may be used to combat chemical decomposition of the base stock oil in the presence of acids. When oil is subjected to ... Alkaline additives are used to neutralize the acids mentioned previously, and also help prevent the formation of sulfates in a ...
Vince lactam
Vince, R.; Hua, M. "Synthesis of carbovir and abacavir from a carbocyclic precursor" Current Protocols in nucleic acid ... including carbocyclic puromycin (I), carbocyclic Ara-A (II), carbovir (III) and guanine as well as azaguanine carbocyclic ... Vince lactam has been extensively used for the preparation of various carbocyclic nucleosides with medicinal applications in ... It is named after Robert Vince who has used the structural features of this molecule for the preparation of carbocyclic ...
Indole
Strong acids such as hydrochloric acid can, however, protonate indole. Indole is primarily protonated at the C3, rather than N1 ... Since the pyrrolic ring is the most reactive portion of indole, electrophilic substitution of the carbocyclic (benzene) ring ... The amino acid tryptophan is an indole derivative and the precursor of the neurotransmitter serotonin. Indole is a solid at ... It is the precursor to indole-3-acetic acid and synthetic tryptophan. The N-H center has a pKa of 21 in DMSO, so that very ...
Silver trifluoromethanesulfonate
Part I. Trifluoromethanesulphonic acid", J. Chem. Soc. (in German), pp. 4228-4232, doi:10.1039/JR9540004228 T. Gramstadt, R.N. ... salts form carbocyclic rings", J. Org. Chem. (in German), vol. 41, no. 17, pp. 2882-2885, doi:10.1021/jo00879a019 Stang, Peter ... Perfluoroalkanesulphonic acids", J. Chem. Soc. (in German), pp. 173-180, doi:10.1039/JR9560000173 G.M. Whitesides, F.D. ... An early preparation method starts from the barium salt of trifluoromethanesulfonic acid (TfOH), from which the free TfOH is ...
Raymond C. Stevens
... and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity J Am Chem Soc 119: 681-90; M. ... The human Lysophosphatidic acid receptor 1 (LPAR1), the human angiotensin II receptor type 1 (AT1R), human P2Y receptor 1 (P2Y1 ... Crystal structure of human lysophosphatidic acid receptor 1 Cell 161: 1633-1643 H. Zhang, H. Unal, C. Gati, G.W. Han, W. Liu, N ... Structure-activity relationships of carbocyclic influenza neuraminidase inhibitors Bioorg Med Chem Lett 7: 1837-1842; C. U. Kim ...
DHQ
... may refer to: 3-Dehydroquinic acid, the first carbocyclic intermediate of the shikimate pathway Digital Humanities ...
Outline of thought
Carbocyclic sugar L-DOPA - Chemical compound Lecithin - Generic term for amphiphilic substances of plant and animal origin ... Amino acid Vasopressin - Mammalian hormone released from the pituitary gland Vinpocetine Vitamin B3, also known as Nicotinic ... Type of α-amino acid Piracetam - Cerebral activators (Nootropil) Pramiracetam Pyritinol (Enerbol) Rhodiola rosea - Species of ... acid - Class of chemically related vitamers Vitamin B5 Vitamin B6 - Class of chemically related vitamins Vitamin B12 - Vitamin ...
Testolactone
... , also known as 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid δ-lactone, is a synthetic 18-oxasteroid ... with a six-membered lactone ring in place of the five-membered carbocyclic D-ring. Testolactone was first approved for medical ...
Carbocyclic nucleoside
Nucleic Acids. 19 (3): 651-690. doi:10.1080/15257770008035015. PMID 10843500. S2CID 43360920. Wang J; Rawal RK; Chu CK (August ... The fluorocarbocyclic nucleoside carbocyclic 2′-ara-fluoro-guanosine was reported in 1988 as the first example of a carbocyclic ... Antiviral Carbocyclic Purine nucleosides (-)Carbovir Abacavir Entecavir Carbocyclic 2′-ara-fluoro-guanosine Entecavir, a ... There are two approaches used in the synthesis of carbocyclic nucleosides. Linear approaches to chiral carbocyclic nucleosides ...
Aminoshikimic acid
It is characterized by multiple stereogenic centers and functional groups arrayed around a six-membered carbocyclic ring. ... As with shikimic acid, aminoshikimic acid is an attractive candidate for use as the core scaffold for synthesis of ... Aminoshikimic acid is also an alternative to shikimic acid as a starting material for the synthesis of neuraminidase inhibitors ... Aminoshikimic acid is an intriguing alternative to shikimic acid as a starting material for the synthesis of neuraminidase ...
Vulpinic acid
Crout, D.H.G. (2012). "The Biosynthesis of Carbocyclic Compounds". In Lloyd, D. (ed.). Carbocyclic Chemistry. Vol. One. ... Vulpinic acid is derived biosynthetically by esterification from pulvinic acid; pulvinate itself derives from the aromatic ... both of which derive from aromatic amino acids such as phenylalanine via secondary metabolism. The roles of vulpinic acid are ... Vulpinic acid is a natural product first found in and important in the symbiosis underlying the biology of lichens. It is a ...
Caffeic acid
"Chemical Land". Caffeic Acid as Carbocyclic Carboxylic Acid. (Chemical articles with multiple compound IDs, Multiple chemicals ... Umbellic acid (2,4-dihydroxycinnamic acid) 2,3-Dihydroxycinnamic acid 2,5-Dihydroxycinnamic acid Gould, Kevin S.; Markham, ... Caffeate O-methyltransferase is an enzyme responsible for the transformation of caffeic acid into ferulic acid. Caffeic acid ... 4-dicarboxylic acid). Caffeic acid can also be polymerized using the horseradish peroxidase/H2O2 oxidizing system. Caffeic acid ...
3-Dehydroquinic acid
... (DHQ) is the first carbocyclic intermediate of the shikimate pathway. It is created from 3- ... 3-Dehydroquinic acid undergoes five further enzymatic steps in the remainder of the shikimate pathway to chorismic acid, a ... 3-Dehydroquinate goes through beta oxidation, similar to fatty acids. Then, this compound (6-oxo-3-dehydro-quinate) is ... Morrow, Gary W. (2016). "The Shikimate Pathway: Biosynthesis of Phenolic Products from Shikimic Acid". Oxford University Press ...
Cyclopropane fatty acid
"Carbocyclic fatty acids in plants: Biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of ... Cyclopropene fatty acids are even rarer than CPAs. The best-known examples are malvalic acid and sterculic acid. Sterculic acid ... Cyclopropane fatty acids (CPA) are a subgroup of fatty acids that contain a cyclopropane group. Although they are usually rare ... which catalyzes the biodesaturation of stearic acid to oleic acid. At least one review indicates that CPFA are carcinogenic, co ...
Methylene cyclopropyl acetic acid
Dihydrosterculic acid is the major carbocyclic fatty acid in the seed oils of Litchi chinensis. It is a cyclopropane fatty acid ... Biochem J 1962;82:385-9. PMC 1243468 "Natural alicyclic fatty acids, section:Cyclopropane and Cyclopropene Fatty Acids from ... Methylene cyclopropyl acetic acid (MCPA) is a compound found in lychee (Litchi chinensis) seeds. It is also a metabolite in ... Methylene cyclopropyl acetic acid (MCPA) is found in lychee seeds and also a toxic metabolite in mammalian digestion after ...
Intramolecular reactions of diazocarbonyl compounds
5) In the presence of a catalytic amount of acid, diazomethyl ketone substrates containing a pendant double bond or aryl group ... 7) Transannular insertions, which form fused carbocyclic products, have also been observed. Yields are often low for these ... 11) A solution of the olefinic acid (0.499 g, 2.25 mmol) dissolved in benzene (20 ml, freshly distilled from calcium hydride) ... Very often, the diazocarbonyl compound is prepared and immediately used via treatment of the corresponding acid chloride with ...
Aromaticity
Hofmann, A. W. (1855). "On Insolinic Acid". Proceedings of the Royal Society. 8: 1-3. doi:10.1098/rspl.1856.0002. Rocke, A. J ... Aromaticity also occurs in compounds that are not carbocyclic or heterocyclic; inorganic six-membered-ring compounds analogous ... The four aromatic amino acids histidine, phenylalanine, tryptophan, and tyrosine each serve as one of the 20 basic building- ... Examples include trinitrotoluene (TNT), acetylsalicylic acid (aspirin), paracetamol, and the nucleotides of DNA. Aromatic ...
Artemisinin
Dihydroartemisinic acid then undergoes photo-oxidation to produce dihydroartemisinic acid hydroperoxide. Ring expansion by the ... and desilylation steps performed on this mono-carbocyclic intermediate, including a final singlet oxygen-utilizing ... The synthesized artemisinic acid can then be transported out, purified and chemically converted into artemisinin that they ... A three-step oxidation of amorpha-4,11-diene gives the resulting artemisinic acid. The UC Berkeley method was augmented using ...
Ferrier carbocyclization
A carbocyclic ring closure of a hex-5-enopyranoside derivative". J. Chem. Soc., Perkin Trans. 1: 1455-1458. doi:10.1039/ ... worked in the same reaction as a milder version of the Lewis acid, i-Bu3Al, which goes through a similar transition state ... Das, SK; Mallet, J-M; Sinaÿ, P (1997). "Novel Carbocyclic Ring Closure of Hex-5-enopyranosides". Angew. Chem. Int. Ed. 36 (5): ... Barton, DHR; Camara, J; Dalko, P; Géro, SD; Quiclet-Sire, B; Stütz, P (1989). "Synthesis of biologically active carbocyclic ...
Cyclononatetraene
E 17b, 4th Edition Supplement: Carbocyclic Three-Membered Ring Compounds, Cyclopropanes: Synthesis. Goettingen: Georg Thieme ... showing that cyclononatetraene is a weaker acid than cyclopentadiene. Cyclononatetraenyl cation is an 8π system. Its ...
Discovery and development of cyclooxygenase 2 inhibitors
The substituted phenyl group at the top of the channel interacts with the side-chains of amino acid residues through ... that is fused in this stilbene system has been extensively manipulated to include every imaginable heterocyclic and carbocyclic ... Celecoxib is metabolized primarily by CYP2C9 isoenzyme to carboxylic acid and also by non-CYP-dependent glucuronidation to ... These compounds differ greatly from NSAIDs that are arylalkonic acid analogs. Encouraged by the "concept testing" experiments ...
Benzotriazole
A synthesis of the BTA involves the reaction of o-phenylenediamine, sodium nitrite, and acetic acid. The conversion proceeds ... methodology is not only limited to heterocyclization but was also successful for polynuclear hydrocarbons of small carbocyclic ... Biphenylene and benzyne can be conveniently prepared from benzotriazole by N-amination with hydroxylamine-O-sulfonic acid. The ... the BTA can lose a proton to act as a weak acid (pKa = 8.2) or accept a proton using the lone pair electrons located on its ...
Inositol
Phytic acid also occurs in cereals with high bran content. Phytate is, however, not directly bioavailable to humans in the diet ... Inositol, or more precisely myo-inositol, is a carbocyclic sugar that is abundant in the brain and other mammalian tissues; it ... "Phytic acid". www.phytochemicals.info. Archived from the original on 2017-08-06. Retrieved 2017-10-02. Reynolds, J. E. F. (1993 ... "Phytic acid". www.phytochemicals.info. Archived from the original on 7 March 2018. Retrieved 2018-05-02. Klopfenstein, T. J.; ...
Organolithium reagent
4-Biphenylacetic Acid and 4-Biphenylcarboxylic Acid/Triphenylmethane as Indicators in the Titration of Lithium Alkyls. Study of ... Another application that takes advantage of this reactivity is the formation of carbocyclic and heterocyclic compounds by ... Lithium enolate formation can be generalized as an acid-base reaction, in which the relatively acidic proton α to the carbonyl ... Organolithium reagents are also better than Grignard reagents in their ability to react with carboxylic acids to form ketones. ...
Cofactor F430
... having a γ-lactam ring E and a keto-containing carbocyclic ring F. It is the only natural tetrapyrrole containing nickel, an ... out a 6-electron and 7-proton reduction of the ring system in a reaction EC 6.3.3.7 generating the 15,173-seco-F430-173-acid ( ...
Heterocyclic compound
Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related ... either carbocyclic or heterocyclic, have a variety of common and systematic names. For example, with the benzo-fused ... Some noteworthy developments: 1818: Brugnatelli isolates alloxan from uric acid 1832: Dobereiner produces furfural (a furan) by ... treating starch with sulfuric acid 1834: Runge obtains pyrrole ("fiery oil") by dry distillation of bones 1906: Friedlander ...
Danheiser annulation
... in the presence of a Lewis Acid to give a trialkylsilylcyclopentene in a regiocontrolled annulation. R. L. Danheiser; D. J. ... New Annulation Approaches to Five and Six-Membered Carbocyclic Compounds". Tetrahedron Letters. 26 (21): 2513. doi:10.1016/ ...
Piroxicam
Tiaprofenic acid (tiaprofenate). *Vedaprofen; Anthranilic acids (fenamic acids): Etofenamic acid (etofenamate). *Floctafenic ... Agonists: Carbocyclic thromboxane A2. *I-BOP. *Thromboxane A2. *U-46619 ...
Lornoxicam
Tiaprofenic acid (tiaprofenate). *Vedaprofen; Anthranilic acids (fenamic acids): Etofenamic acid (etofenamate). *Floctafenic ... Agonists: Carbocyclic thromboxane A2. *I-BOP. *Thromboxane A2. *U-46619 ...
Intramolecular Heck reaction
The reaction may be used to produce carbocyclic or heterocyclic organic compounds with a variety of ring sizes. Chiral ... scopadulcic acid. A 6-exo cyclization sets the quaternary center and provides a neopentyl σ-palladium intermediate, which ...
Kevlar
"Wholly aromatic carbocyclic polycarbonamide fiber having orientation... - US 3819587 A - IP.com". ip.com. Tatsuya Hongū, Glyn O ... Kevlar production is expensive because of the difficulties arising from using concentrated sulfuric acid, needed to keep the ... and terephthaloyl chloride in a condensation reaction yielding hydrochloric acid as a byproduct. The result has liquid- ...
Stieglitz rearrangement
... by which carboxylic acids can be transformed into amines through the addition of hydrazoic acid under acidic aqueous conditions ... "Carbocyclic Ring Construction via an Intramolecular Diels-Alder Reaction of an in-Situ Generated, Heteroatom-Stabilized Allyl ... In a Beckmann rearrangement, the acid catalyzed carbon to nitrogen migration takes place on the oxime to yield a nitrilium ion ... When subjecting the azide to a Brønsted acid, the protonation of the azide activates the basal nitrogen and lowers the bond ...
Propellane
It was first synthesized in 2018 using a general strategy for the synthesis of carbocyclic propellanes from 1,3- ... and spontaneously reacts with acetic acid to form a methylenecyclobutane ester. Several synthetic procedures are established ... "Asymmetric Synthesis of Carbocyclic Propellanes". Org. Lett. 19 (9): 2310-2313. doi:10.1021/acs.orglett.7b00836. PMID 28445060 ...
Bicyclic molecule
A bicyclic compound can be carbocyclic (all of the ring atoms are carbons), or heterocyclic (the rings' atoms consist of at ... B. Smith, "Organic Chemistry: An Acid-Base Approach", Taylor & Francis, 2011, Page 302, https://books.google.nl/books?id= ...
Robert Vince (scientist)
Vince continued his work on antiviral drug candidates at the University of Minnesota, where he went on to develop carbocyclic ... Nucleotides and Nucleic Acids, in 2010. The same year, Minnesota Inventor's Congress inducted him into Minnesota Inventors Hall ... Nucleotides and Nucleic Acids ACS Medicinal Chemistry Hall of Fame (Articles with short description, Short description matches ... Nucleotides and Nucleic Acids April 2010: Received Honorary Doctorate of Science Degree from SUNY Buffalo September 2009: ...
Carbocyclic nucleoside - Wikipedia
Nucleic Acids. 19 (3): 651-690. doi:10.1080/15257770008035015. PMID 10843500. S2CID 43360920. Wang J; Rawal RK; Chu CK (August ... The fluorocarbocyclic nucleoside carbocyclic 2′-ara-fluoro-guanosine was reported in 1988 as the first example of a carbocyclic ... Antiviral Carbocyclic Purine nucleosides (-)Carbovir Abacavir Entecavir Carbocyclic 2′-ara-fluoro-guanosine Entecavir, a ... There are two approaches used in the synthesis of carbocyclic nucleosides. Linear approaches to chiral carbocyclic nucleosides ...
Advanced Search Results - Public Health Image Library(PHIL)
US4284796A - Preparation of 4-acyloxy-2-methyl-crotonaldehydes - Google Patents
... with water in the presence of a carboxylic acid of the formula R--COOH III. ... C07C-ACYCLIC OR CARBOCYCLIC COMPOUNDS * C07C67/00-Preparation of carboxylic acid esters ... 3. The process of claim 1, wherein the carboxylic acid of the formula III is acetic acid. ... 150000001732 carboxylic acid derivatives Chemical class 0.000 claims abstract description 11 * 238000000034 method Methods ...
Fenoprofen | Harvard Catalyst Profiles | Harvard Catalyst
CN106661030 Improved forms of PI3K delta selective inhibitor for use in pharmaceutical formulations
The present invention relates to solid state forms of a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta ... ACYCLIC OR CARBOCYCLIC COMPOUNDS. 309. Sulfonic acids; Halides, esters, or anhydrides thereof. 01. Sulfonic acids. 28. having ... EN) The present invention relates to solid state forms of a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta ...
Advanced Search Results - Public Health Image Library(PHIL)
3 Or 4 Amino Acid Residues In The Peptide Chain Patents and Patent Applications (Class 514/21.9) - Justia Patents Search
Search for 3 Or 4 Amino Acid Residues In The Peptide Chain Patents and Patent Applications (Class 514/21.9) Filed with the ... Abstract: This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically ... Containing Doai Patents 3 Or 4 Amino Acid Residues In The Peptide Chain Patents (Class 514/21.9) 3 Or 4 Amino Acid Residues In ... Carboxylic acid-containing small molecules can be used in the methods and compositions disclosed herein, for example, sulindac ...
PT3149000 IMPROVED FORMS OF A PI3K DELTA SELECTIVE INHIBITOR FOR USE IN PHARMACEUTICAL FORMULATIONS
Widespread Oseltamivir Resistance in Influenza A Viruses (H1N1), South Africa - Volume 14, Number 11-November 2008 - Emerging...
LIPID MAPS® Lipidomics Gateway
Alepramic acid. 3-(2-cyclopenten-1-yl)-propanoic acid. Fatty Acids and Conjugates [FA01]. Carbocyclic fatty acids [FA0114]. ... 2-octynoic acid. 2-octynoic acid. Fatty Acids and Conjugates [FA01]. Unsaturated fatty acids [FA0103]. 140.08. C8H12O2. ... 7-octynoic acid. 7-octynoic acid. Fatty Acids and Conjugates [FA01]. Unsaturated fatty acids [FA0103]. 140.08. C8H12O2. ... 5,7-octadienoic acid. 5,7-octadienoic acid. Fatty Acids and Conjugates [FA01]. Unsaturated fatty acids [FA0103]. 140.08. C8H12O ...
Flux profiling of photosynthetic carbon metabolism in intact plants | Nature Protocols
Carbocyclic fatty acids in plants: biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of ... Ong, S.-E. & Mann, M. A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC). Nat. Protoc. 1, ... Lipps, S.H. & Beevers, H. Compartmentation of organic acids in corn roots I. differential labeling of 2 malate pools. Plant ... Tomato aromatic amino acid decarboxylases participate in synthesis of the flavor volatiles 2-phenylethanol and 2- ...
Gallic Acid | Profiles RNS
Acids, Carbocyclic [D02.241.223]. *Benzoates [D02.241.223.100]. *Hydroxybenzoates [D02.241.223.100.300]. *Gallic Acid [D02.241. ... "Gallic Acid" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Gallic Acid" by people in this website by year, and whether " ... Suppression of TNF-? induced NF?B activity by gallic acid and its semi-synthetic esters: possible role in cancer ...
1-NAPHTHOIC ACID (1-NAPHTHALENECARBOXYLIC ACID)
alpha-Naphthylcarboxylic acid; Naphthalene-alpha-carboxylic acid; alpha-Naphthoic acid; 1-Maythic acid; Isonaphthoic acid; ... CARBOCYCLIC CARBOXYLIC ACIDS PHYSICAL AND CHEMICAL PROPERTIES. PHYSICAL STATE. white to off white crystals. ... 1-Naphthoic acid is used as an intermediate for the synthesis of pharmaceuticals, photochemicals, plant growth hormones, dyes ...
Chemistry Tree - Thimmaiah Govindaraju
β-PEPTIDES CYCLOBUTANIQUES - TEL - Thèses en ligne
The bibliographical section, divided into two parts, describes the synthesis deβ-amino acids carbocyclic then the different ... Abstract : The synthesis of β-amino acids, structural analogues of?-Amino acids, is an issue essential in the development of ... amino acids). As a result, the conformational preference of β-amino acids will induce the appearance of a three-dimensional ... A lot of work has been conducted on the behavior of β-peptide (sequence of β-amino acids) as well as peptides mixed (mixed β- ...
Parabens | Harvard Catalyst Profiles | Harvard Catalyst
Recent applications of barbituric acid in multicomponent reactions - RSC Advances (RSC Publishing)
There is a wide range of multicomponent reactions that include barbituric acid as starting material. This article aims to revie ... Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbocyclic compounds and ... Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbocyclic compounds and ... Recent applications of barbituric acid in multicomponent reactions G. Mohammadi Ziarani, F. Aleali and N. Lashgari, RSC Adv., ...
Properties of oligonucleotide with phenyl-substituted carbocyclic nucleoside analogs for the formation of duplex and triplex...
In: Nucleosides, Nucleotides and Nucleic Acids, Vol. 31, No. 12, 01.12.2012, p. 841-860.. Research output: Contribution to ... Nasr T, Taniguchi Y, Takaki T, Okamura H, Sasaki S. Properties of oligonucleotide with phenyl-substituted carbocyclic ... Therefore, the skeleton of the phenyl-substituted carbocyclic nucleoside analog 10 may be a platform for the formation of ... Therefore, the skeleton of the phenyl-substituted carbocyclic nucleoside analog 10 may be a platform for the formation of ...
Dibutyl Phthalate | Colorado PROFILES
Synthesis and Antiviral Activity of Carbocyclic Analogues of Xylofuranosides of 2-Amino-6-substituted-purines and 2-Amino-6...
Mefenamic acid
... is a member of the anthranilic acid derivatives (or fenamate) class of NSAID drugs, and is used ... Agonists: Carbocyclic thromboxane A2. *I-BOP. *Thromboxane A2. *U-46619 ... Mefenamic acid is recommended to be taken with food.[7]. Known mild side effects of mefenamic acid include headaches, ... Valerian constituents (e.g., isovaleric acid, isovaleramide, valerenic acid, valerenol). *Unsorted benzodiazepine site positive ...
o-Phthalaldehyde | Colorado PROFILES
DeCS Ingl s
D02.241 Carboxylic Acids .. D02.241.223 Acids, Carbocyclic .. D02.241.223.701 Phenylpropionates .. D02.241.223.701.350 ... Cromoglycic Acid .. Cromolyn .. FPL-670 .. Intal .. Lomudal .. Nalcrom .. Nasalcrom .. Opticrom .. Vicrom .. Acid, Cromoglicic ... Acid, Cromoglycic .. Cromoglycate, Disodium .. Cromoglycate, Sodium .. FPL 670 .. FPL670 .. Sodium Cromoglycate .. Disodium ...
Dinitolmide | Profiles RNS
Metrizoate | Profiles RNS
Methylphenidate | Profiles RNS
Nitrobenzoates | Profiles RNS
Carboxylic Acids [D02.241]. *Acids, Carbocyclic [D02.241.223]. *Benzoates [D02.241.223.100]. *Nitrobenzoates [D02.241.223.100. ... Benzoic acid or benzoic acid esters substituted with one or more nitro groups. ... Use of a microplate reader in an assay of glutathione reductase using 5,5-dithiobis(2-nitrobenzoic acid). Anal Biochem. 1989 ...
Iopamidol | Profiles RNS
Phenylpyruvic Acids | Profiles RNS
Below are MeSH descriptors whose meaning is related to "Phenylpyruvic Acids".. *Acids, Carbocyclic ... "Phenylpyruvic Acids" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Phenylpyruvic Acids" by people in this website by year, and ... A group of compounds that are derivatives of phenylpyruvic acid which has the general formula C6H5CH2COCOOH, and is a ...
British Library EThOS: The α-alkylation of ketones using hydrogen borrowing catalysis
... and seven-membered carbocyclic rings. The optimisation of the reactions conditions is described followed by a systematic ... followed by trapping with several nucleophiles led to the formation of carboxylic acid derivatives. The final part of the ... investigation into the diastereoselectivity observed in the formation of the carbocyclic rings. With the formation of ...
CompoundsSynthesisDerivativesRing carbocyclic nucleosidesNucleosidesFattyAnaloguesLactic acidAmino acidMolecularMoietyEstersRacemicMethionineSkeletons2019EnzymesSolventSubstituentsInositolIntramolecularCycloadditionCOMPOUNDSEstersCarboxylicThioctic AcidAmino AcidsLipidsNucleic AcidsFatty acidsEnantioselectiveSubstancesMeSHAnalogueAldehydeConjugatesPentanoicAlkylLewisCarbonClassProprietaryAmine
Compounds14
- A large number of novel carbocyclic nucleosides of pyrimidines and purines have been prepared, and many of these compounds are endowed with interesting biological activities. (wikipedia.org)
- 1-Naphthoic acid is used as an intermediate for the synthesis of pharmaceuticals, photochemicals, plant growth hormones, dyes and other organic compounds. (chemicalland21.com)
- The bibliographical section, divided into two parts, describes the synthesis deβ-amino acids carbocyclic then the different types of secondary structures of peptides derived from β-amino acid compounds. (archives-ouvertes.fr)
- Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbocyclic compounds and considered as an important building block in organic synthesis. (rsc.org)
- This article aims to review the chemistry of barbituric acids employed in the design and synthesis of different types of compounds during the period from 2011 to 2015. (rsc.org)
- A group of compounds that are derivatives of phenylpyruvic acid which has the general formula C6H5CH2COCOOH, and is a metabolite of phenylalanine. (childrensmercy.org)
- 18. Yu Bai, Weijie Tao, Jun Ren and Zhongwen Wang* "Lewis Acid Catalyzed Intramolecular [4+2] and [3+2] Cross-Cycloaddition of Alkynylcyclopropane Ketones with Carbonyl Compounds and Imines" Angew. (nankai.edu.cn)
- In organic chemistry, Dicarboxylic Acids are a subclass of organic compounds , in the carboxylic acid class in the organic acids superclass , containing exactly two carboxylic acid groups. (wellnessadvantage.com)
- Dicarboxylic Acid compounds are acyclic acid compounds, that contains two carboxylic acid groups and have the formula HO 2 C-R-CO 2 H, where R may be either an aromatic or aliphatic functional group. (wellnessadvantage.com)
- Metal-catalyzed hydrofunctionalization reactions of alkynes, i.e., the addition of Y-H units (Y = heteroatom or carbon) across the carbon-carbon triple bond, have attracted enormous attention for decades since they allow the straightforward and atom-economic access to a wide variety of functionalized olefins and, in its intramolecular version, to relevant heterocyclic and carbocyclic compounds. (sciencegate.app)
- Recently, Brønsted acids such as HNTf2 and HOTf have been shown to be powerful activators that promote catalytic alkyne alkoxylation/Claisen rearrangement, leading to the concise and flexible synthesis of valuable compounds with high efficiency and atom economy. (sciencegate.app)
- They are known as carbocyclic or alicyclic compounds. (msvgo.com)
- They can be further subdivided into two categories: carbocyclic compounds and heterocyclic compounds. (tutorcity.sg)
- These secondary compounds are primarily classified on the basis of their carbocyclic skeletons into pseudoguainolides, guaianalides, germanocranolides, eudesmanolides, heliangolides and hyptocretenolides etc (Figure 1). (dosingpdf.com)
Synthesis12
- There are two approaches used in the synthesis of carbocyclic nucleosides. (wikipedia.org)
- 1966: First described synthesis of the racemic (±) carbocyclic analogue of adenosine. (wikipedia.org)
- 1988: Review of Glaxo's synthesis of fluorocarbocyclic nucleosides 1988: (±)-Carbovir first reported with potent anti-HIV activity and low cytotoxicity 1992: First comprehensive review of the synthesis of chiral carbocyclic nucleosides. (wikipedia.org)
- The synthesis of β-amino acids, structural analogues of? (archives-ouvertes.fr)
- This work on the synthesis of optically pure ACBC and the behavior of β-peptides cyclobutaniques completes the picture of carbocyclic β-peptides. (archives-ouvertes.fr)
- To address carbocyclic fatty acid synthesis in plants, a cDNA library was constructed from developing seeds during the period of maximum oil deposition. (typeset.io)
- Morandi, B. Nickel‐Catalyzed Cascade Annulation for the Rapid Synthesis of Carbocyclic Nitriles. (mpg.de)
- Morandi, B. CO- and HCl-Free Synthesis of Acid Chlorides from Unsaturated Hydrocarbons Via Shuttle Catalysis. (mpg.de)
- The key carbocyclic allylic alcohol intermediate 5-methoxymethylcyclopent-2-enol was synthesized via a six step synthesis in racemic form from the ethylene-acetal of 2-methoxymethylcyclopentanone but attempts at deprotection of the methyl ether proved unsuccessful. (shu.ac.uk)
- This chapter discusses the methods of formation, synthesis, properties and reactions of anthracenes and its homologs such as alkyl-, aryl-anthracenes, aminoanthracenes, hydroxyanthracenes (anthrols), anthracenecarboxylic acids and their functional derivatives. (bath.ac.uk)
- Brijesh M. Sharma, Mahesh Yadav, Rajesh G. Gonnade And and Pradeep Kumar*, Unified Approach to Fused and Spirocyclic Oxindoles through Lewis-Acid-Promoted Opening of Spiroepoxyoxindoles with Allylsilanes: Application to the Formal Synthesis of (±)-Physovenine, Eur. (ncl.res.in)
- The AB plus D strategy for tetracycline synthesis by C-ring construction is shown to be robust across a range of different carbocyclic and heterocyclic D-ring precursors, proceeding reliably and with a high degree of stereochemical control. (health-articles.net)
Derivatives7
- This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. (justia.com)
- Mefenamic acid is a member of the anthranilic acid derivatives (or fenamate) class of NSAID drugs, and is used to treat mild to moderate pain, including menstrual pain , and is sometimes used to prevent migraines associated with menstruation. (orange.com)
- Like other members of the anthranilic acid derivatives (or fenamate) class of NSAID drugs, it inhibits both isoforms of COX and prevents formation of prostaglandins . (orange.com)
- Scientists led by Claude Winder from Parke-Davis invented mefenamic acid in 1961, along with fellow members of the class of anthranilic acid derivatives , flufenamic acid in 1963 and meclofenamate sodium in 1964. (orange.com)
- Derivatisation of the resulting β-branched products through bromine-initiated release of the aryl group, followed by trapping with several nucleophiles led to the formation of carboxylic acid derivatives. (bl.uk)
- Hydroxylated benzoic acid derivatives that contain mercury. (nih.gov)
- Etheno (and ethano) derivatives of nucleic acid bases have an extra 5-membered ring attached. (biomedcentral.com)
Ring carbocyclic nucleosides1
- The 5-membered ring carbocyclic nucleosides aristeromycin, the analog of adenosine, and neplanocin A, the cyclopentene analog of aristeromycin, have been isolated from natural sources. (wikipedia.org)
Nucleosides5
- Carbocyclic nucleosides (also referred to as carbanucleosides) are nucleoside analogues in which a methylene group has replaced the oxygen atom of the furanose ring. (wikipedia.org)
- The two guanine antiviral carbocyclic nucleosides, the anti-HIV agent abacavir and the anti-hepatitis B agent entecavir, are reverse-transcriptase inhibitors. (wikipedia.org)
- Antiviral Carbocyclic Purine nucleosides (-)Carbovir Abacavir Entecavir Carbocyclic 2′-ara-fluoro-guanosine Entecavir, a guanosine analog, was reported in 1997 as a potent and selective inhibitor for the hepatitis B virus, and approved by the FDA in March 2005 for oral treatment of hepatitis B infection. (wikipedia.org)
- Linear approaches to chiral carbocyclic nucleosides 2 rely on the construction of the heterocyclic base onto a suitable protected chiral cyclopentylamine (1 → 2). (wikipedia.org)
- This amide was easily acid hydrolysed to the amine hydrochloride which was subsequently used to synthesize a variety of purine based nucleosides. (shu.ac.uk)
Fatty11
- A cDNA library was constructed from developing seeds during the period of maximum oil deposition and a CPA-FA synthase was identified from S. foetida, and the pathway in higher plants that produce carbocyclic fatty acids was defined as by transfer of C1 units, most likely from S-adenosylmethionine to oleate. (typeset.io)
- Fatty acids containing three-member carbocyclic rings are found in bacteria and plants. (typeset.io)
- Bacteria synthesize cyclopropane fatty acids (CPA-FAs) only by the addition of a methylene group from S-adenosylmethionine to the cis-double bond of monoenoic phospholipid-bound fatty acids. (typeset.io)
- In plants CPA-FAs are usually minor components with cyclopropene fatty acids (CPE-FAs) more abundant. (typeset.io)
- Functional analysis of the isolated full-length cDNA was conducted in tobacco suspension cells where its expression resulted in the accumulation of up to 6.2% dihydrosterculate of total fatty acids. (typeset.io)
- Together, a CPA-FA synthase was identified from S. foetida, and the pathway in higher plants that produce carbocyclic fatty acids was defined as by transfer of C1 units, most likely from S-adenosylmethionine to oleate. (typeset.io)
- Toporosides A and B, Cyclopentenyl-Containing ω-Glycosylated Fatty Acid Amides, and Toporosides C and D from the Northwestern Pacific Marine Sponge Stelodoryx toporoki . (lipidmaps.org)
- Structurally, arachidonic acid is a 20-carbon fatty acid, present as a component of the phospholipids of the cell membranes. (assignology.com)
- In lipid science , Dicarboxylic Acids [FA0117] are a subclass in the Fatty acyl lipid class [FA] . (wellnessadvantage.com)
- Sodium or potassium salts of fatty acids are gone through decarboxylation. (msvgo.com)
- Feller, S.E. Gawrisch, G. and MacKerell, Jr., A.D. Polyunsaturated !Fatty Acids in Lipid Bilayers: Intrinsic and Environmental !Contributions to Their Unique Physical Properties. (charmm.org)
Analogues1
- Three phencyclidine (PCP) analogues possessing a highly rigid carbocyclic structure and an attached piperidine ring which is free to rotate were synthesized. (thevespiary.org)
Lactic acid1
- Poor laurus nobilis good lauryl alcohol good lauryl glucoside good lauryl lactate mixture of lauryl alcohol and lactic acid that functions as a skin-conditioning agent and… Dd-tv is the only air-based broadcasting corporation in india that provides television service coverage across india and its neighboring nations, including pakistan, nepal and even bangladeshi. (filomena-formaro.de)
Amino acid9
- In the laboratory, we work on the β-amino acid cyclobutane as a building block of molecular structures developed with β-peptides. (archives-ouvertes.fr)
- Work has been conducted on the β-amino acid cyclic 6, 5 and 4-membered ring. (archives-ouvertes.fr)
- However, no work has been described on the trans-cyclobutane β-amino acid "trans-ACBC. (archives-ouvertes.fr)
- The residual amino acid side chain (from methionine) is esterified and acetylated to form wybutosine (Fig. 4 ). (biomedcentral.com)
- Amino acid Isomil 1 showed a lower relative content of β-glycosylated (39.1%) and a higher relative content of acetylglycosilated (28.4%) isoflavones in relation to the three above-mentioned samples. (faah-signal.com)
- Workout enthusiasts have long been educated on L-arginine, an amino acid that's responsible for boosting nitric oxide (NO) levels in the body. (priceplow.com)
- The "M" in MIC Injection, is an essential amino acid, which means that it is not synthesized in humans. (zelkeninstitute.com)
- an amino acid that helps prevent fatigue and works as an anti-oxidant to neutralize toxins in the body. (b12injectionsmiami.com)
- Evolution of amino acid 215 in HIV-1 reverse transcriptase in response to intermittent drug selection. (hivfrenchresistance.org)
Molecular1
- In organic chemistry , Glutaric Acid (Glutarate or Glutaric Oxoacid) is an organic compound the molecular formula (C 3 H 6 (COOH) 2 ). (wellnessadvantage.com)
Moiety1
- In the convergent approach the intact heterocyclic base is coupled directly to a suitably protected functionalised carbocyclic moiety (3 → 2). (wikipedia.org)
Esters4
- induced NF?B activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. (umassmed.edu)
- Benzoic acid or benzoic acid esters substituted with one or more nitro groups. (childrensmercy.org)
- Acid value was decreased by esterification process using sulfuric acid anhydrous (H2SO4) as a catalyst and alkaline (NaOH) catalyst transesterification was carried out for the conversion of crude oil to methyl esters. (typeset.io)
- The salts or esters of salicylic acids, or salicylate esters of an organic acid. (bvsalud.org)
Racemic1
- Abacavir, was developed from racemic (±)-carbovir which was reported in 1988 by Robert Vince as the first carbocyclic nucleoside analogue to show potent activity against HIV with low cytotoxicity. (wikipedia.org)
Methionine2
- In addition, the dihydrosterculate was specifically labeled by [methyl-14C]methionine and by [14C]oleic acid in the transgenic tobacco cells. (typeset.io)
- One of the sulfur-containing amino acids (along with cysteine and cystine), methionine is important (essential) to many bodily functions and must be directly consumed through supplementation or methionine-containing proteins. (zelkeninstitute.com)
Skeletons1
- 16. Siyang Xing, Yan Li, Zhen Li, Chang Liu, Jun Ren and Zhongwen Wang* "Lewis Acid-Catalyzed Intramolecular Cross [3+2] Cycloaddition of Donor-Acceptor Cyclopropanes with Carbonyls: A General Strategy for Construction of Bridge-Acetal[n.2.1] Skeletons" Angew. (nankai.edu.cn)
20191
- [14] In the Philippines, 1 tablet of 500 mg generic mefenamic acid cost PHP25.00 (or the equivalent of US$0.50) as of September 2, 2019. (orange.com)
Enzymes2
- En plus de cette fascinante particularité, les β-peptides et les peptides mixtes ont montré une grande stabilité vis-à-vis des enzymes digestives. (archives-ouvertes.fr)
- The lipoocygenase pathway comprises of lipooxygenases enzymes that act on arachidonic acid and result in the formation of 5-HPETE and 15-HPETE respectively. (assignology.com)
Solvent1
- The effects of solvent, time, temperature and the use of different Lewis acids were studied, showing dramatic effects for solvent and Lewis acid. (unav.edu)
Substituents1
- There are many ways to produce heterocyclic rings, but the most common processes involve the use of precursors to synthesize the desired molecule, modification of an existing heterocyclic or carbocyclic ring, or modifying the substituents on an existing heterocycle. (cabb-chemicals.com)
Inositol2
- Also known as myo-inositol, inositol is best described as a carbocyclic polyol, which forms the basis for many signaling and secondary messenger molecules. (zelkeninstitute.com)
- Inositol, or more precisely myo-inositol, is a carbocyclic sugar that is abundant in brain and other mammalian tissues, mediates cell signal transduction in response to a variety of hormones, neurotransmitters and growth factors and participates in osmoregulation. (nanochemia.ir)
Intramolecular3
- 4. Bao Hu, Siyang Xing, Zhongwen Wang* "Lewis Acid Catalyzed Ring-Opening Intramolecular Friedel-Crafts Alkylation of Methylenecyclopropane 1,1-Diesters" Org. (nankai.edu.cn)
- 13. Bao Hu, Jun Ren, Zhongwen Wang* "Lewis acid-catalyzed nucleophilic ring-opening/intramolecular Conia-ene reactions of methylenecyclopropane 1,1-diesters with propargyl alcohols" Tetrahedron 2011, 67(04), 763-768. (nankai.edu.cn)
- Recent advances on the Brønsted acid catalyzed alkyne alkoxylation/Claisen rearrangement are introduced in this Account, in which both intramolecular and intermolecular tandem reactions are discussed. (sciencegate.app)
Cycloaddition1
- vital reactions equivalent to carbo- and hetero-Diels-Alder, carbocyclic, cyclopropanation and 1,3-dipolar cycloaddition reactions are mentioned. (kkt.as)
COMPOUNDS2
Esters4
- In addition to two isomeric (E)-caffeoyl ethyl tartrates, the glucose esters of (E)-cinnamic, (E)-p-coumaric, and (E)-ferulic acid, as well as the 4-O-glucosides of (E)- and (Z)-ferulic acid, have been identified for the first time in Riesling wine. (nih.gov)
- Moreover, two ethyl esters, i.e., ethyl protocatechuate and ethyl gallate, as well as the glucose ester of vanillic acid, were newly detected in Riesling wine. (nih.gov)
- Polyphosphoric acids, 2-[alkyl-1-oxo-2-propen-1-yl)oxy]ethyl esters, compds. (toxplanet.com)
- Facile Transformation of α,β-Unsaturated Carboxylic Acids to Alkenylboronic Esters via Rhodium-catalyzed Decarbonylative Borylation of α,β-Unsaturated Thioesters. (riken.jp)
Carboxylic2
- Carboxylic acids that have open-chain molecular structures as opposed to ring-shaped structures. (umassmed.edu)
- Rhodium-Catalyzed Decarbonylative Borylation of Aromatic Thioesters for Facile Diversification of Aromatic Carboxylic Acids. (riken.jp)
Thioctic Acid2
- This graph shows the total number of publications written about "Thioctic Acid" by people in this website by year, and whether "Thioctic Acid" was a major or minor topic of these publications. (ouhsc.edu)
- Below are the most recent publications written about "Thioctic Acid" by people in Profiles. (ouhsc.edu)
Amino Acids2
- This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. (pandudesign.com)
- SAFE & UNIQUE INGREDIENTS: Amberen is a proprietary blend of succinates, amino acids, vitamin E, and minerals. (thesmartchoose.com)
Lipids1
- Straight-chain fatty acids and cyclic fatty acids in lipids during maturation of the seeds. (lipidmaps.org)
Nucleic Acids2
- Inspired by the cytochrome P450 catalyzed transformation of furan into a reactive enal species, we recently introduced a furan-oxidation-based methodology for cross-linking of nucleic acids. (ugent.be)
- These furan-modified nucleic acids can form interstrand cross-links upon selective furan oxidation with N-bromosuccinimide. (ugent.be)
Fatty acids1
- New cyclopentenyl fatty acids in Flacourtiaceae. (lipidmaps.org)
Enantioselective3
- Uncovering the differential forces between the ground and transition structures with chiral Lewis acids is a perquisite step towards the creation of more effective enantioselective catalysts. (duq.edu)
- Specifically, bis(oxazoline) copper(II) complexes operate as enantioselective Lewis acid catalysts for carbocyclic and hetero Diels-Alder reactions. (duq.edu)
- The functionalization of indoles in the carbocyclic ring has been achieved via organocatalytic enantioselective Friedel-Crafts benzhydrylation of hydroxyindoles with in situ generated ortho-quinomethanes in oil-water biphases, allowing an efficient access to varied diarylindolylmethanes with a wide substrate scope. (bvsalud.org)
Substances1
- Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic pandudesign.com: Peter A. Jacobi. (pandudesign.com)
MeSH2
- Abscisic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
- Acids, Acyclic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Analogue3
- Incorporation of the carbocyclic analogue of (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate into a synthetic DNA. (neb.com)
- The replacement of the ring oxygen with a methylene group to generate a carbocyclic analogue leads to enhancement of its chemical stability. (unimi.it)
- Herein, we report conjugation of carbocyclic analogue monomer, dimer, and trimer to the protein carrier CRM197. (unimi.it)
Aldehyde2
- 1-azirine 3-position acetic acid adduct aldehyde alkaloids alkene alkyl amine anhydride aromatic azetidine aziridine azirine base basic benzene benzene ring benzo benzofuran bond Bromination carbon atoms carbonyl CH3 CH3 Chem Chemical Reactions Chemistry chloride condensation COOC2H5 COOCH3 COOH cyclization cycloaddition derivatives diaziridine 3/5(6). (pandudesign.com)
- Dicarboxylic acids in which one of the carboxyl groups (-COOH) has been replaced by an aldehyde group (-CHO). (bvsalud.org)
Conjugates2
- Conjugates with longer carbocyclic oligomers and/or precise acetylation patterns could further increase the induced immune response to a level comparable with those of commercially available anti-meningococcal glycoconjugate vaccines. (unimi.it)
- These building blocks offer a new, facile and shorter access route to bile acid-peptide conjugates on solid-phase with emphasis on heterodipodal conjugates with defined spatial arrangements. (ugent.be)
Pentanoic1
- An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. (ouhsc.edu)
Alkyl1
- The homologs of phenanthrene include the alkyl-phenanthrenes, aminophenanthrenes or phenanthrylamines, hydroxyphenanthrenes or phenanthrols, formyl- and acyl-phenanthrenes, phenanthrenecarboxylic acids, phenanthrene quinones and biphenanthryls. (bath.ac.uk)
Lewis6
- Yang and co-workers also tried lower-temperature conditions in the presence of various Lewis acids but these were also unsuccessful. (nature.com)
- My Ph.D. dissertation describes three different external influences on pericyclic reactions: (1) ionic liquids, (2) Lewis acids and (3) bis(oxazoline)-Cu(II) complexes. (duq.edu)
- 2) Lewis acids are known to influence strongly the rate, regio, endo/exo, diastereofacial and enantio selectivities of the Diels-Alder reaction. (duq.edu)
- Our efforts focus upon a novel combination of two specific intermolecular interactions between boron Lewis acids and Diels-Alder transition structures. (duq.edu)
- Principles of Chemical Reactivity on the Diels-Alder Reaction in Ionic Liquids and Lewis Acid Catalysis using Large-Scale Computations (Doctoral dissertation, Duquesne University). (duq.edu)
- This is the first example of metal-catalyzed asymmetric transformations of the in situ generated p-QMs, avoiding using pre-synthesized p-QMs requiring bulky 2,6-substitutions and highlighting a new dual catalytic activation with the chiral bis(oxazoline)-metal complex acting as a normal Lewis acid to activate the ß-ketoesters and a source of Brønsted acid responsible for generating the p-QMs in situ. (bvsalud.org)
Carbon1
- The carbon-metal bond of the ferrocene structure was a new concept of p-bonding of a carbocyclic ring to a metal atom. (subjecto.com)
Class1
- lt;p>Polydiphenylenephthalide (PDP) belongs to the class of carbocyclic organic electroactive polymers, which exhibit electric conductive properties when an external electric field and/or mechanical stress is applied. (beilstein-archives.org)
Proprietary1
- Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. (drugbank.com)
Amine1
- Kevlar is synthesized in solution from the monomers 1,4- phenylene -di amine ( para -phenylenediamine ) and terephthaloyl chloride in a condensation reaction yielding hydrochloric acid as a byproduct. (knowpia.com)