OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation Science
OrganophosphonatesPhosphorous AcidsFosfomycinOrganophosphorus CompoundsAminoethylphosphonic AcidAbstracting and Indexing as TopicNucleotidesTretinoinCarcinoma, HepatocellularNeoplasms, Second PrimaryPeriodicals as TopicLiver NeoplasmsPubMedBooksMuscle RigidityPeptide Nucleic AcidsNucleic Acid HybridizationNucleic Acid DenaturationRNAL FormsNucleic Acid ConformationMannich BasesOrganic Chemistry PhenomenaFluorine CompoundsIsobutyratesKetonesIminesStereoisomerismMetabolomeIlliciumElectrophoresis, CapillaryMetabolomicsAnticarcinogenic AgentsDirectories as TopicMolecular BiologyTemplates, GeneticNucleosidesAdenosineArthropodsNucleoside-Triphosphatase
Organophosphonates
Carbon-containing phosphonic acid compounds. Included under this heading are compounds that have carbon bound to either OXYGEN atom or the PHOSPHOROUS atom of the (P=O)O2 structure.
Phosphorous Acids
Inorganic derivatives of phosphorus trihydroxide (P(OH)3) and its tautomeric form dihydroxyphosphine oxide (HP=O(OH)2). Note that organic derivatives of phosphonic acids are listed under are ORGANOPHOSPHONATES.
Fosfomycin
An antibiotic produced by Streptomyces fradiae.
Organophosphorus Compounds
Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.
Aminoethylphosphonic Acid
An organophosphorus compound isolated from human and animal tissues.
Abstracting and Indexing as Topic
Activities performed to identify concepts and aspects of published information and research reports.
Nucleotides
The monomeric units from which DNA or RNA polymers are constructed. They consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
Tretinoin
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
Neoplasms, Second Primary
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
Periodicals as Topic
A publication issued at stated, more or less regular, intervals.
Liver Neoplasms
Tumors or cancer of the LIVER.
PubMed
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Books
Muscle Rigidity
Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
Peptide Nucleic Acids
DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.
Nucleic Acid Hybridization
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Nucleic Acid Denaturation
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.
RNA
A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
L Forms
Bacterial variants, unable to form a complete cell wall, which are formed in cultures by various bacteria; granules (L bodies) appear, unite, and grow into amorphous bodies which multiply and give rise to bacterial cells morphologically indistinguishable from the parent strain.
Nucleic Acid Conformation
The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.
Mannich Bases
Ketonic amines prepared from the condensation of a ketone with formaldehyde and ammonia or a primary or secondary amine. A Mannich base can act as the equivalent of an alpha,beta unsaturated ketone in synthesis or can be reduced to form physiologically active amino alcohols.
Organic Chemistry Phenomena
The conformation, properties, reaction processes, and the properties of the reactions of carbon compounds.
Fluorine Compounds
Inorganic compounds that contain fluorine as an integral part of the molecule.
Isobutyrates
Aliphatic acids that contain four carbons in a branched-chain configuration. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the 2-carboxypropane structure.
Ketones
Imines
Stereoisomerism
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Metabolome
The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.
Illicium
A plant genus of the family Illiciaceae, order Illiciales, subclass Magnoliidae, class Magnoliopsida. They have evergreen, aromatic leaves and bisexual flowers. The female portion of the flower consists of 7 to 15 carpels.
Electrophoresis, Capillary
A highly-sensitive (in the picomolar range, which is 10,000-fold more sensitive than conventional electrophoresis) and efficient technique that allows separation of PROTEINS; NUCLEIC ACIDS; and CARBOHYDRATES. (Segen, Dictionary of Modern Medicine, 1992)
Metabolomics
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
Anticarcinogenic Agents
Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.
Directories as Topic
Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)
Molecular Biology
A discipline concerned with studying biological phenomena in terms of the chemical and physical interactions of molecules.
Templates, Genetic
Macromolecular molds for the synthesis of complementary macromolecules, as in DNA REPLICATION; GENETIC TRANSCRIPTION of DNA to RNA, and GENETIC TRANSLATION of RNA into POLYPEPTIDES.
Nucleosides
Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
Adenosine
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
Arthropods
Members of the phylum Arthropoda, composed of organisms having a hard, jointed exoskeleton and paired jointed legs. It includes the class INSECTS and the subclass ARACHNIDA, many species of which are important medically as parasites or as vectors of organisms capable of causing disease in man.
Nucleoside-Triphosphatase
An enzyme which catalyzes the hydrolysis of nucleoside triphosphates to nucleoside diphosphates. It may also catalyze the hydrolysis of nucleotide triphosphates, diphosphates, thiamine diphosphates and FAD. The nucleoside triphosphate phosphohydrolases I and II are subtypes of the enzyme which are found mostly in viruses.

3,4-Dihydrocoumarin hydrolase with haloperoxidase activity from Acinetobacter calcoaceticus F46. (1/16)

A novel lactonohydrolase, an enzyme that catalyzes the hydrolysis of 3,4-dihydrocoumarin, was purified 375-fold to apparent homogeneity, with a 22.7% overall recovery, from Acinetobacter calcoaceticus F46, which was isolated as a fluorene-assimilating micro-organism. The molecular mass of the native enzyme, as estimated by high-performance gel-permeation chromatography, is 56 kDa, and the subunit molecular mass is 30 kDa. The enzyme specifically hydrolyzes 3,4-dihydrocoumarin, and the Km and Vmax for 3,4-dihydrocoumarin are 0.806 mM and 4760 U.mg-1, respectively. The N-terminal and internal amino acid sequences of the enzyme show high similarity to those of bacterial non-heme haloperoxidases. The enzyme exhibits brominating activity with monochlorodimedon in the presence of H2O2 and 3, 4-dihydrocoumarin or an organic acid, such as acetate and n-butyrate.  (+info)

Al-induced efflux of organic acid anions is poorly associated with internal organic acid metabolism in triticale roots. (2/16)

The secretion of organic acid anions from roots has been identified as a mechanism of resistance to Al. However, the process leading to the secretion of organic acid anions is poorly understood. The effect of Al on organic acid metabolism was investigated in two lines of triticale (xTriticosecale Wittmark) differing in Al-induced secretion of malate and citrate and in Al resistance. The site of Al-induced secretion of citrate and malate from a resistant line was localized to the root apices (terminal 5 mm). The levels of citrate (root apices and mature root segments) and malate (mature segments only) in roots increased during exposure to Al, but similar changes were observed in both triticale genotypes. The in vitro activities of four enzymes involved in malate and citrate metabolism (citrate synthase, phosphoenolpyruvate carboxylase, malate dehydrogenase, and NADP-isocitrate dehydrogenase) were similar for sensitive and resistant lines in both root apices and mature root segments. The response of these enzymes to pH did not differ between tolerant and sensitive lines or in the presence and absence of Al. Moreover, cytoplasmic and vacuolar pH were not affected by exposure to Al in either line. Together, these results indicate that the Al-dependent efflux of organic acid anions from the roots of triticale is not regulated by their internal levels in the roots or by the capacity of the root cells to synthesize malate and citrate.  (+info)

Propionyl-coenzyme A synthetases of Ralstonia solanacearum and Salmonella choleraesuis display atypical kinetics. (3/16)

Propionyl-coenzyme A synthetases (PrpE) of Salmonella choleraesuis and Ralstonia solanacearum sharing 62% identity in amino acid sequence to each other were cloned, expressed in Escherichia coli and purified. Both enzymes catalyzed acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A formation with the highest k(cat)/K(m) values for propionate. They displayed sigmoidal homotrophic autoactivation kinetics for propionate but not for the other acyl substrates tested. Besides, substrate inhibition kinetics was observed for co-substrates, i.e. ATP and CoA. Based on the kinetic data reported herein, the reaction mechanisms of the enzyme are discussed.  (+info)

The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer. (4/16)

In previous work, we showed that the binding of the liver x receptor alpha:peroxisome proliferator-activated receptor alpha (LXRalpha:PPARalpha) heterodimer to the murine Cyp7a1 gene promoter antagonizes the stimulatory effect of their respective ligands. In this study, we determined if LXRalpha:PPARalpha can also regulate human CYP7A1 gene promoter activity. Co-expression of LXRalpha and PPARalpha in McArdle RH7777 hepatoma cells decreased the activity of the human CYP7A1 gene promoter in response to fibrates and 25-hydroxycholesterol. In vitro, the human CYP7A1 Site I bound LXRalpha:PPARalpha, although with substantially less affinity compared with the murine Cyp7a1 Site I. The binding of LXRalpha:PPARalpha to human CYP7A1 Site I was increased in the presence of either LXRalpha or PPARalpha ligands. In HepG2 hepatoblastoma cells, fibrates and 25-hydroxycholesterol inhibited the expression of the endogenous CYP7A1 gene as well as the human CYP7A1 gene promoter when co-transfected with plasmids encoding LXRalpha and PPARalpha. However, a derivative of the human CYP7A1 gene promoter that contains a mutant form of Site I that does not bind LXRalpha:PPARalpha was not inhibited by WY 14,643 or 25-hydroxycholesterol in both McArdle RH7777 and HepG2 cells. The ligand-dependent recruitment of LXRalpha:PPARalpha heterodimer onto the human CYP7A1 Site I can explain the inhibition of the human CYP7A1 gene promoter in response to fibrates and 25-hydroxycholesterol.  (+info)

Corn hybrid affects in vitro and in vivo measures of nutrient digestibility in dogs. (5/16)

Corn is a commonly used ingredient in dry pet foods because there is a stable supply and it is a relatively inexpensive source of nutrients. Corn hybrids are available that are higher in CP and amylose and lower in phytate concentration than conventional hybrids. Approximately 500 mg of high-protein (HP), high-protein, low-phytate (HPLP), and high-amylose (HA) corn were compared with conventional (CONV) corn and amylomaize starch (AM) in triplicate and exposed to pepsin/hydrochloric acid and pancreatin to simulate hydrolytic digestion. Substrate remaining after this was used to determine in vitro colonic fermentation. Organic matter disappearances as a result of hydrolytic digestion were >80% for CONV, HP, and HPLP, whereas HA (60.7%) and AM (43.7%) were lower (P < 0.05). Total digestion (TD) values after hydrolytic digestion and 8 h of fermentation using canine fecal inoculum were greater (P < 0.05) for CONV, HP, and HPLP vs. HA and AM. The residue left after hydrolytic digestion of all substrates was poorly fermented. Five ileal-cannulated dogs were fed each corn hybrid at approximately 31% of the diet in a 5 x5 Latin square design. Dogs fed diets containing HP corn had higher (P < 0.05) ileal OM digestibility (70.3%) and tended (P < 0.10) to have higher DM digestibility (64.6%). Ileal starch digestibilities were lower (P < 0.05) for dogs fed HA (64.0%) and AM (63.0%). Ileal digestibilities of essential (71.2%), nonessential (67.4%), and total (69.0%) AA tended to be higher (P < 0.10) for HP diets compared with CONV (66.4, 62.4, and 64.0%, respectively). Total-tract DM, OM, CP, and GE digestibilities (77, 82, 77, and 84%, on average, respectively) were higher (P < 0.05) for dogs fed CONV, HP, and HPLP than for those fed AM (66.9, 71.6, 72.6, and 76.5%) and HA (60.6, 65.7, 69.7, and 71.5%). Total-tract fat digestibilities were lower (P < 0.05) for dogs fed HA diets (86.6%) than for all other treatments (91.0%, on average). Total-tract starch digestibilities were higher (P < 0.05) for dogs fed CONV, HP, and HPLP (98%, on average) compared with HA (72.8%) and AM (76.5%). No differences were detected among treatments in fecal bifidobacteria, lactobacilli, or Clostridium perfringens concentrations. The experiments demonstrated that HP and HPLP corn had hydrolytic digestion and fermentation characteristics similar to those of CONV corn, whereas HA resulted in similar responses to AM, a well-established resistant starch ingredient.  (+info)

Enantioselective fluorescent recognition of chiral acids by cyclohexane-1,2-diamine-based bisbinaphthyl molecules. (6/16)

The cyclohexane-1,2-diamine-based bisbinaphthyl macrocycles (S)-/(R)-5 and their cyclic and acyclic analogues are synthesized. The interactions of these compounds with various chiral acids are studied. Compounds (S)-/(R)-5 exhibit highly enantioselective fluorescent responses and high fluorescent sensitivity toward alpha-hydroxycarboxylic acids and N-protected amino acids. Among these interactions, (S)-mandelic acid (10(-3) M) led to over 20-fold fluorescence enhancement of (S)-5 (1.0 x 10(-5) M in benzene/0.05% DME) at the monomer emission, and (S)-hexahydromandelic acid (10(-3) M) led to over 80-fold fluorescence enhancement. These results demonstrate that (S)-5 is useful as an enantioselective fluorescent sensor for the recognition of the chiral acids. On the basis of the study of the structures of (S)-5 and the previously reported 1,2-diphenylethylenediamine-based bisbinaphthyl macrocycle (S)-4, the large fluorescence enhancement of (S)-5 with a chirality-matched alpha-hydroxycarboxylic acid is attributed to the formation of a structurally rigidified host-guest complex and the further interaction of this complex with the acid to suppress the photoinduced electron-transfer fluorescent quenching caused by the nitrogens in (S)-5.  (+info)

Bioactive constituents from Chinese natural medicines. XXVIII. Chemical structures of acyclic alcohol glycosides from the roots of Rhodiola crenulata. (7/16)

Five new glycosides, creosides I, II, III, IV, and V, were isolated from the methanolic extract of the roots of Rhodiola crenulata, together with 21 known compounds. The chemical structures of new constituents were elucidated on the basis of chemical and physicochemical evidence.  (+info)

Mutation of the active site carboxy-lysine (K70) of OXA-1 beta-lactamase results in a deacylation-deficient enzyme. (8/16)

 (+info)

Ennature Biopharma (Division of India Glycols Limited)公司提供的DHA 40% -- 食品、飲料與營養保健品Ennature Biopharma (Division of India Glycols Limited)公司提供的DHA 40% -- 食品、飲料與營養保健品
DHA 40% is an unsaturated acyclic acid that is a golden-yellow to yellow colored flowable soft liquid. This product should be stored at | 5℃ under nitro...
https://www.ulprospector.com/zh-tw/asia/Food/Detail/4711/131503/DHA-40
Icariin exerts estrogen-like activity in ameliorating EAE via mediating estrogen receptor β, modulating HPA function and...Icariin exerts estrogen-like activity in ameliorating EAE via mediating estrogen receptor β, modulating HPA function and...
Icariin exerts estrogen-like activity in ameliorating EAE via mediating estrogen receptor β, modulating HPA function and glucocorticoid receptor expression ...
http://www.msdiscovery.org/papers/biblio/30255-icariin-exerts-estrogen-activity-ameliorating-eae-mediating-estrogen-receptor-%CE%B2
Overview of Amino Acid and Organic Acid Metabolism Disorders - Pediatrics - Merck Manuals Professional EditionOverview of Amino Acid and Organic Acid Metabolism Disorders - Pediatrics - Merck Manuals Professional Edition
Overview of Amino Acid and Organic Acid Metabolism Disorders - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
https://www.merckmanuals.com/professional/pediatrics/inherited-disorders-of-metabolism/overview-of-amino-acid-and-organic-acid-metabolism-disorders
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3,4-dihydrocoumarin - Registration Dossier - ECHA3,4-dihydrocoumarin - Registration Dossier - ECHA
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
https://www.echa.europa.eu/sv/web/guest/registration-dossier/-/registered-dossier/22066
ChemIDplus - 102506-09-2 - SLSORSYCKMNPIJ-UHFFFAOYSA-N - (Cyclohexane-1,2-diylbis(nitrilobis(methylene)))tetrakisphosphonicacid...ChemIDplus - 102506-09-2 - SLSORSYCKMNPIJ-UHFFFAOYSA-N - (Cyclohexane-1,2-diylbis(nitrilobis(methylene)))tetrakisphosphonicacid...
102506-09-2 - SLSORSYCKMNPIJ-UHFFFAOYSA-N - (Cyclohexane-1,2-diylbis(nitrilobis(methylene)))tetrakisphosphonicacid, sodium salt - Similar structures search, synonyms, formulas, resource links, and other chemical information.
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Valproic Acid | Profiles RNSValproic Acid | Profiles RNS
Price KE, Pearce RE, Garg UC, Heese BA, Smith LD, Sullivan JE, Kennedy MJ, Bale JF, Ward RM, Chang TK, Abbott FS, Leeder JS. Effects of valproic acid on organic acid metabolism in children: a metabolic profiling study. Clin Pharmacol Ther. 2011 Jun; 89(6):867-74 ...
https://researchers.childrensmercy.org/display/16744
NMR SpectrumNMR Spectrum
cyclohexane-1,3-dione 504-02-9 NMR spectrum, cyclohexane-1,3-dione H-NMR spectral analysis, cyclohexane-1,3-dione C-NMR spectral analysis ect.
http://www.molbase.com/en/hnmr_504-02-9-moldata-38743.html
Estro-PX - Your Holistic DocEstro-PX - Your Holistic Doc
Estro-Px provides comprehensive herbal support during times of rapid hormonal changes, such as the menopausal transition. This unique combination of herbal extracts contains high levels of phytoestrogens, naturally-occurring plant substances that bind to estrogen receptor sites and promote estrogen-like activity. In
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CRYSTALLINE FORMS OF (1RS,2RS,6RS)-6-DIMETHYLAMINOMETHYL-1-(3-METHOXYPHENYL)CYCLOHEXANE-1,3-DI- OL HYDROCHLORIDE -...CRYSTALLINE FORMS OF (1RS,2RS,6RS)-6-DIMETHYLAMINOMETHYL-1-(3-METHOXYPHENYL)CYCLOHEXANE-1,3-DI- OL HYDROCHLORIDE -...
TABLE-US-00001 TABLE 1 Peak and Relative Intensity Listing (degree 2θ, peaks with I/I1 value) Peak No. A I/I1 B I/I1 C I/I1 D I/I1 E I/I1 1 12.87 35 6.43 29 6.55 7 10.28 9 6.76 8 2 13.25 11 9.67 46 11.89 22 12.74 21 9.68 35 3 14.08 12 10.52 30 12.19 26 13.02 26 10.74 18 4 14.28 18 12.57 17 12.58 26 13.54 18 13.96 16 5 15.77 14 13.61 64 12.97 20 13.7 21 14.50 11 6 16.09 9 14.24 42 14.05 46 14.1 20 14.94 24 7 16.62 23 14.64 70 14.93 17 15.78 21 16.62 21 8 17.53 30 16.34 52 15.39 19 16.24 10 17.52 10 9 17.92 27 17.05 23 15.89 13 17.5 15 17.90 10 10 18.95 79 17.54 58 16.35 17 17.94 40 19.20 20 11 19.29 100 19.34 20 17.25 29 18.6 66 20.44 15 12 20.04 21 20.36 29 17.44 55 19.04 100 21.38 100 13 20.38 10 20.64 100 18.34 20 19.90 50 23.28 13 14 21.01 47 21.06 83 19.47 100 20.4 18 24.18 19 15 21.99 8 21.61 40 19.96 58 21.1 17 25.16 12 16 23.84 8 22.06 33 21.14 48 21.92 10 25.18 12 17 24.68 17 23.17 23 22.27 15 23.58 23 25.20 10 18 25.28 40 23.56 23 22.84 9 25.3 19 25.22 11 19 25.83 9 23.92 15 23.37 40 ...
http://www.patentsencyclopedia.com/app/20110306673
Patent EP13731450 - CYCLOHEXANE-1,2-NAPHTHALEN... - IP Industry BasePatent EP13731450 - CYCLOHEXANE-1,2-NAPHTHALEN... - IP Industry Base
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Benzeneacetic acid, alpha-[[(1,1-dimethylethoxy)carbonyl]amino]-4-[2-(methylamino)-2-oxoethoxy]-, (R),Benzeneacetic acid, alpha...Benzeneacetic acid, alpha-[[(1,1-dimethylethoxy)carbonyl]amino]-4-[2-(methylamino)-2-oxoethoxy]-, (R),Benzeneacetic acid, alpha...
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TRC | Details of CAS = 326496-02-0, ChemicalName = 6-[[2-(tert-Butyldimethylsilyloxy)ethyl]methylamino]pyridin-3-ol, synonym =...TRC | Details of CAS = 326496-02-0, ChemicalName = 6-[[2-(tert-Butyldimethylsilyloxy)ethyl]methylamino]pyridin-3-ol, synonym =...
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4-{(1S)-1-Hydroxy-2-[(<sup>2</sup>H<sub>3</sub>)methylamino]ethyl}-1,2-benzenediol |...4-{(1S)-1-Hydroxy-2-[(<sup>2</sup>H<sub>3</sub>)methylamino]ethyl}-1,2-benzenediol |...
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Maize ZmALMT2 is a root anion transporter that mediates constitutive root malate efflux - GOV.UKMaize ZmALMT2 is a root anion transporter that mediates constitutive root malate efflux - GOV.UK
Root efflux of organic acid anions underlies a major mechanism of plant aluminium (Al) tolerance on acid soils. This efflux is mediated by transporters of the Al-activated malate transporter (ALMT) or the multi-drug and toxin extrusion (MATE) families. ZmALMT2 was previously suggested to be involved in Al tolerance based on joint association-linkage mapping for maize Al tolerance. In the current study, we functionally characterized ZmALMT2 by heterologously expressing it in Xenopus laevis oocytes and transgenic Arabidopsis. In oocytes, ZmALMT2 mediated an Al-independent electrogenic transport product of organic and inorganic anion efflux. Ectopic overexpression of ZmALMT2 in an Al-hypersensitive Arabidopsis KO/KD line lacking the Al tolerance genes, AtALMT1 and AtMATE, resulted in Al-independent constitutive root malate efflux which partially restored the Al tolerance phenotype. The lack of correlation between ZmALMT2 expression and Al tolerance (e.g., expression not localized to the root tip, ...
https://www.gov.uk/dfid-research-outputs/maize-zmalmt2-is-a-root-anion-transporter-that-mediates-constitutive-root-malate-efflux
Temperature desynchronizes sugar and organic acid metabolism in ripening grapevine fruits and remodels their transcriptome |...Temperature desynchronizes sugar and organic acid metabolism in ripening grapevine fruits and remodels their transcriptome |...
Fruit composition at harvest is strongly dependent on the temperature during the grapevine developmental cycle. This raises serious concerns regarding the sustainability of viticulture and the socio-economic repercussions of global warming for many regions where the most heat-tolerant varieties are already cultivated. Despite recent progress, the direct and indirect effects of temperature on fruit development are far from being understood. Experimental limitations such as fluctuating environmental conditions, intra-cluster heterogeneity and the annual reproductive cycle introduce unquantifiable biases for gene expression and physiological studies with grapevine. In the present study, DRCF grapevine mutants (microvine) were grown under several temperature regimes in duly-controlled environmental conditions. A singly berry selection increased the accuracy of fruit phenotyping and subsequent gene expression analyses. The physiological and transcriptomic responses of five key stages sampled simultaneously
https://bmcplantbiol.biomedcentral.com/articles/10.1186/s12870-016-0850-0
Salmonella Choleraesuis in Swine - eXtensionSalmonella Choleraesuis in Swine - eXtension
Contents 1 Salmonella choleraesuis in Swine 1.1 History 1.2 Etiology 1.3 Zoonotic Potential 1.4 Epidemiology 1.5 The Disease 1.6...
http://articles.extension.org/pages/27268/salmonella-choleraesuis-in-swine
Phosphate-solubilizing peanut associated bacteria: screening for plant growth-promoting activities | SpringerLinkPhosphate-solubilizing peanut associated bacteria: screening for plant growth-promoting activities | SpringerLink
In the present study, attempts were made to identify the potential of bacterial strains for promoting Arachis hypogaea L. growth. Four hundred and thirty three bacteria were isolated from rhizosphere,
https://link.springer.com/article/10.1007%2Fs11104-009-0168-x
Characterization of aluminium-induced citrate secretion in aluminium-tolerant soybean (Glycine max) plants - Yang - 2001 -...Characterization of aluminium-induced citrate secretion in aluminium-tolerant soybean (Glycine max) plants - Yang - 2001 -...
Recently, we showed that secretion of citrate in an aluminium (Al) tolerant cultivar soybean (Glycine max) (cv. Suzunari) is a specific response to Al stress [Yang et al. (2000) Physiol Plant 110: 72-77]. Here we investigated the intrinsic mechanisms behind the secretion of citrate induced by Al. The amount of citrate secreted during the 24-h Al treatment period increased with increasing concentration of Al (0-70 μM). We analysed citrate secretion basically under 3 conditions: (1) by varying light-exposure, (2) with intact or excised shoots and (3) by using a divided chamber technique. Further, the content of organic acids in the tissue and the activity of enzymes involved in organic acid metabolism were analysed and evaluated. The results indicate that high rate of citrate secretion in soybean requires a 4-h induction period. Al had a continuous effect on the citrate secretion when Al was removed from the treatment solution. Citrate secretion increased steadily under exposure to continuous ...
http://onlinelibrary.wiley.com/doi/10.1034/j.1399-3054.2001.1130109.x/full
tris({[(9,10-dioxo-8a,9,10,10a-tetrahydroanthracen-2-yl)amino]methylidene})cyclohexane-1,3,5-trione nanowirestris({[(9,10-dioxo-8a,9,10,10a-tetrahydroanthracen-2-yl)amino]methylidene})cyclohexane-1,3,5-trione nanowires
Page contains details about tris({[(9,10-dioxo-8a,9,10,10a-tetrahydroanthracen-2-yl)amino]methylidene})cyclohexane-1,3,5-trione nanowires . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
http://nano.nature.com/nano/GR-M8689355
EnergyForce , 90 CapsulesEnergyForce , 90 Capsules
Fatigue is not just a lack of physical energy; mental exhaustion can also contribute to an overall lack of energy and endurance. EnergyForce™ is a non-stimulant formula that includes the nutrients necessary to naturally support both physical and mental energy without the jitters or anxiety associated with some energy supplements.. Clinical research has shown that the botanical extracts in Endurin TG™, Rhodiola crenulata and Rhodiola rosea, help reduce fatigue and promote vitality. They also provide adaptogenic support that provides an increase in the bodys ability to cope on multiple physiological levels.. Panax Ginseng and Eleuthero root have been studied for centuries for enhancing vitality. Ginsengs activity has been shown to increase nonspecific immunostimulatory activity, while Eleuthero Root helps increase the bodys resistance to external negative forces and creates an overall normalizing affect.. EnergyForce™ contains an energizing compound of complementary nutrients and herbs, ...
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9 CFR 113.122 - Salmonella Choleraesuis Bacterin. | US Law | LII / Legal Information Institute9 CFR 113.122 - Salmonella Choleraesuis Bacterin. | US Law | LII / Legal Information Institute
c)Potency test. Bulk or final container samples of completed product from each serial shall be tested for potency using the mouse test provided in this paragraph. A mouse dose shall be 1/20 of the least dose recommended on the label for other animals which shall not be less than 2 ml. (1) The ability of the bacterin being tested (Unknown) to protect mice shall be compared with a Standard Reference Bacterin (Standard) which is either supplied by or acceptable to Veterinary Services. (2) At least three fivefold dilutions shall be made with the Standard and the same fivefold dilution shall be made for each Unknown. The dilutions shall be made in Phosphate-Buffered Saline. (3) For each dilution of the Standard and each dilution of an Unknown, a group of at least 20 mice, each weighing 16 to 22 grams, shall be used. Each mouse in a group shall be injected intraperitoneally with one mouse dose of the appropriate dilution. Each mouse shall be revaccinated on day 14, using the same schedule. (4) Each of ...
https://www.law.cornell.edu/cfr/text/9/113.122
españolespañol
Titulo en español: Caracterización de bacterias diazotróficas solublizadoras de fosfato como promotoras de crecimiento en plantas de maízTitulo corto: Caracterización de bacterias diazotróficasAbstract: Phosphorus is limiting for growth of maize plants, and because of that use of fertilizers like rock phosphate has been proposed. However, direct use of rock phosphate is not recommended because of its low availability, so it is necessary to improve it. In this study, a group of diazotrophic bacteria were evaluated as phosphate-solubilizing bacteria, for their production of indolic compounds and for their effects on growth of maize plants. Strains of the genera Azosporillum, Azotobacter, Rhizobium and Klebsiella, were quantitatively evaluated for solubilization of Ca3(PO4)2 and Rock Phosphate as a single source of phosphorous in SRS culture media. Additionally, the phosphatase enzyme activity was quantified at pH 5.0, 7.0 and 8.0 using p-nitrophenyl phosphate, and production of indolic ...
https://repositorio.unal.edu.co/handle/unal/71393?locale-attribute=es
CAS 2212-32-0 2-((2-(dimethylamino)ethyl)methylamino)-ethanol, - BOC SciencesCAS 2212-32-0 2-((2-(dimethylamino)ethyl)methylamino)-ethanol, - BOC Sciences
Boc Sciences is the worlds leading provider for special chemicals. We offer qualified products for 2212-32-0(2-((2-(dimethylamino)ethyl)methylamino)-ethanol,),please inquire us for 2212-32-0(2-((2-(dimethylamino)ethyl)methylamino)-ethanol,).
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Deriving Value from Multi-Hybrid Planting | Pioneer SeedsDeriving Value from Multi-Hybrid Planting | Pioneer Seeds
Precision farming pioneers long envisioned that corn hybrids could be an important input for variable management, considering that corn hybrid selection is one of the most important factors for maximizing yield. Review common strategies for variable placement of corn hybrids and key findings from Pioneer and university multi-hybrid planting trials.
https://www.pioneer.com/us/agronomy/value-from-multi-hybrid-planting.html
Benzoic acid,2-[[(1,1-dimethylethoxy)carbonyl]methylamino]- - Alfa ChemistryBenzoic acid,2-[[(1,1-dimethylethoxy)carbonyl]methylamino]- - Alfa Chemistry
Benzoic acid,2-[[(1,1-dimethylethoxy)carbonyl]methylamino]-/ACM141871025 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
http://www.alfa-chemistry.com/cas_141871-02-5.htm
Lab Report - WriteWorkLab Report - WriteWork
A ph is a -log(h3,0+). An indicator is a weak organic acids whose color differs from that of its conjugate.A buffer is a soluton that can receive moderate amounts of either acid or base without significant change in its ph. Neutralization is combinig e...
http://www.writework.com/essay/lab-report
TRC | Details of CAS = 359436-59-2, ChemicalName = 4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid...TRC | Details of CAS = 359436-59-2, ChemicalName = 4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid...
Buy high quality 4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid Salt 359436-59-2 from toronto research chemicals Inc.
https://www.trc-canada.com/product-detail/?M139000
The Crazy Mass - 100% Legal Muscle Building Steroids: April 2016The Crazy Mass - 100% Legal Muscle Building Steroids: April 2016
Zinc oxide and vitamin B6 are regarded as the really effective part which plays an essential job in raising the testosterone amount, which is essential for accelerating the hormones and would make you healthful. This product or service can be acquiring wealthy information of minerals which fulfills the deficiency of primary need of your body. Rhodiola crenulata may be very valuable in protecting the cortisol degree of the human body and manages the pressure level and tends to make you able to focus on your goal in a much better way. Tribulu terrestris is a traditional aspect which usually to blame for simulation of blood throughout the physique and Additionally, it considered as incredibly handy in production of libiodo, dont concern yourself with your reduced push. By using this awesome product you can make your body healthier from each side i.e internally as well as externally. Nitric oxide is having its attribute of opening the blood vessel for suitable flowing of blood through the entire ...
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Quinoline ether alkanoic acid.Quinoline ether alkanoic acid.
Compounds having the formula: are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, ...
http://patent.ipexl.com/EP/0349062-a1.html
2S)-2-[[(2S)-2-[(2-amino-4-methylpentyl)-methylamino]-4-methylpentanoyl]amino]-N-[(2S)-3-(1H-indol-3-yl)-1-oxo-1-[[(2S)-1-oxo-1...2S)-2-[[(2S)-2-[(2-amino-4-methylpentyl)-methylamino]-4-methylpentanoyl]amino]-N-[(2S)-3-(1H-indol-3-yl)-1-oxo-1-[[(2S)-1-oxo-1...
(2S)-2-[[(2S)-2-[(2-amino-4-methylpentyl)-methylamino]-4-methylpentanoyl]amino]-N-[(2S)-3-(1H-indol-3-yl)-1-oxo-1-[[(2S)-1-oxo-1-(2-oxoethylideneamino)-3-phenylpropan-2-yl]amino]propan-2-yl]pentanediamide 135721-56-1 MSDS report, (2S)-2-[[(2S)-2-[(2-amino-4-methylpentyl)-methylamino]-4-methylpentanoyl]amino]-N-[(2S)-3-(1H-indol-3-yl)-1-oxo-1-[[(2S)-1-oxo-1-(2-oxoethylideneamino)-3-phenylpropan-2-yl]amino]propan-2-yl]pentanediamide MSDS safety technical specifications search, (2S)-2-[[(2S)-2-[(2-amino-4-methylpentyl)-methylamino]-4-methylpentanoyl]amino]-N-[(2S)-3-(1H-indol-3-yl)-1-oxo-1-[[(2S)-1-oxo-1-(2-oxoethylideneamino)-3-phenylpropan-2-yl]amino]propan-2-yl]pentanediamide safety information specifications ect.
http://www.molbase.com/en/msds_135721-56-1-moldata-88850.html
Alfa Aesar™ 4-(Methylamino)phenol sulfate, ACS, 99.0-101.5% 50g Alfa Aesar™ 4-(Methylamino)phenol sulfate, ACS, 99.0-101.5%Alfa Aesar™ 4-(Methylamino)phenol sulfate, ACS, 99.0-101.5% 50g Alfa Aesar™ 4-(Methylamino)phenol sulfate, ACS, 99.0-101.5%
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Preparation and properties of 6-substituted cyclohexane-1,2,4-triol derivatives: mechanistic probes for the inositol...Preparation and properties of 6-substituted cyclohexane-1,2,4-triol derivatives: mechanistic probes for the inositol...
Thank you for your interest in spreading the word about Biochemical Society Transactions.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
http://www.biochemsoctrans.org/content/26/3/315
Organic Acid Supply Information Organic Acid Suppliers and Manufacturers on weiku.comOrganic Acid Supply Information Organic Acid Suppliers and Manufacturers on weiku.com
Organic Acid Products catalog and Organic Acid manufacturer directory. weiku.com is a Organic Acid trade platform offering information about Global Organic Acid Products and global Organic Acid buyers
http://www.weiku.com/catalogs/1013/Organic_Acid/
ethyl 2-(methylamino)acetate | C5H11NO2 - PubChemethyl 2-(methylamino)acetate | C5H11NO2 - PubChem
ethyl 2-(methylamino)acetate | C5H11NO2 | CID 95849 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/ethyl_2-_methylamino_acetate
2-[[2-(2-Hydroxyethoxy)ethyl]methylamino]ethanol - Alfa Chemistry2-[[2-(2-Hydroxyethoxy)ethyl]methylamino]ethanol - Alfa Chemistry
2-[[2-(2-Hydroxyethoxy)ethyl]methylamino]ethanol/ACM68213989 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
http://www.alfa-chemistry.com/cas_68213-98-9.htm
Immunoassay ProductsImmunoassay Products
Surfaces with primary or secondary amino groups covalently bound are dedicated to promote the covalent immobilisationof compounds containing reactive moieties such as amino, carboxyl or thiol groups via well-known homoheterobifunctionallinkers, e.g. N-Hydroxysuccinimide (NHS) or Succinimidyl 4-(N-maleidomethyl) cyclohexane-1-carboxylate (SMCC).. This kind of immobilisation can overcome some of the limitations connected with physical adsorption of the molecules tothe surfaces:. ...
http://immunosurface.com/search_immunoassay?sub_category_id=5&surface_id=13
Immunoassay ProductsImmunoassay Products
Surfaces with primary or secondary amino groups covalently bound are dedicated to promote the covalent immobilisationof compounds containing reactive moieties such as amino, carboxyl or thiol groups via well-known homoheterobifunctionallinkers, e.g. N-Hydroxysuccinimide (NHS) or Succinimidyl 4-(N-maleidomethyl) cyclohexane-1-carboxylate (SMCC).. This kind of immobilisation can overcome some of the limitations connected with physical adsorption of the molecules tothe surfaces:. ...
http://immunosurface.com/search_immunoassay?sub_category_id=5&surface_id=14
DL-Isoserine - Creative PeptidesDL-Isoserine - Creative Peptides
R)-2-(Methylamino)-3-phenylpropanoicacid;56564-52-4;N-methyl-d-phenylalanine;AmbotzHAA1199;N-Me-D-Phe-OH;L-Phenylalanine,N-methyl-;SCHEMBL161255;AC1O533H;MolPort-008-267-985;SCIFESDRCALIIM-SECBINFHSA-N;MFCD00069560;ZINC12954903;AKOS006283223;CS17818;AJ-63161;AK144741;KB-58622;FT-0693770;(2R)-2-(methylamino)-3- ...
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Category:Limonia acidissima - Wikimedia CommonsCategory:Limonia acidissima - Wikimedia Commons
Limonia (es); Limonia acidissima (ast); poma de closca (ca); Limonia acidissima (de); Limonia acidissima (sq); لیمونیا اکیدیسیما (fa); 象橘 (zh); Bista (mad); Limonia acidissima (ro); ゾウノリンゴ (ja); Elefantäpple (sv); Деревяне яблуко (uk); Limonia acidissima (la); कबिट (hi); వెలగ (te); Limonia acidissima (fi); விளா (ta); Limonia acidissima (it); কৎ বেল (bn); Limonia acidissima (fr); Kawis (jv); Slonova jabuka (hr); Kawista (id); कवठ (mr); କଇଥ (or); Limonia (pt); Limonia acidissima (ga); Hesperethusa crenulata (vi); Limonia acidissima (war); ಬೆಳವಲ (kn); תפוח הפילים (he); Limonia acidissima (ceb); දිවුල් (si); Limonia acidissima (bg); มะขวิด (th); Feronia słoniowa (pl); വിളാവ് (ml); olifantsappel (nl); သီးပင် (my); Kawista (ban); ڪويٺ (sd); Деревянное яблоко (ru); Limonia acidissima (en); تفاح الخشب (ar); ...
https://commons.wikimedia.org/wiki/Category:Limonia_acidissima?uselang=hr
cephalexin: Topics by WorldWideScience.orgcephalexin: Topics by WorldWideScience.org
Phenotypic and Genotypic Features of a Salmonella Heidelberg Strain Isolated in Broilers in Brazil and Their Possible Association to Antibiotics and Short-Chain Organic Acids Resistance and Susceptibility.. Santin, Elizabeth; Hayashi, Ricardo Mitsuo; Wammes, Jessica Caroline; Gonzalez-Esquerra, Ricardo; Carazzolle, Marcelo Falsarella; Freire, Caio César de Melo; Monzani, Paulo Sérgio; da Cunha, Anderson Ferreira. 2017-01-01. Salmonella enterica serovar Heidelberg is a human pathogen also found in broilers. A strain (UFPR1) has been associated with field reports of resistance to short-chain organic acids (SCOA) in broilers in the South of Brazil, but was susceptible to a Bacillus subtilis -based probiotic added in feed in a related study. This work aimed to (i) report clinical symptoms caused by SH UFPR1 in broilers, (ii) study its susceptibility to some antibiotics in vitro , and (iii) SCOA in vivo ; and (iv) relate these phenotypic observations with its genome characteristics. Two in vivo ...
https://worldwidescience.org/topicpages/c/cephalexin.html
Method for hypoestrogen-induced endothelial dysfunction correction with lozartan in complex with mixed solutions of...Method for hypoestrogen-induced endothelial dysfunction correction with lozartan in complex with mixed solutions of...
the invention relates to medicine, in particular to the experimental cardiovascolari.. Closest to the claimed solution is a way of correcting hypoestrogen-induced endothelial dysfunction furostanol glycosides from cell culture plants of dioscorea deltoidea described 27.07.2008, RF patent No. 2329807.. The main disadvantage of this method is that the correction geoastro-meningocerebral endothelial disfuncio associated with estrogen-like activity furostanol glycosides. Therefore, the results of the correction of endothelial dysfunction in case of damage in the system L-arginine-NO, which is mainly caused by deficiency of endothelial NO-synthase, using furostanol glycosides from cell culture plants of dioscorea deltoidea with estrogen-like activity is unsatisfactory.. While the main mechanism of action of the mixture of solutions gomeopaticheskih dilutions of polyclonal rabbit antibodies to endothelial synthase nitric oxide - C12, C30, C200 is an increase of eNOS, thereby affecting the main link of ...
https://russianpatents.com/patent/243/2437162.html
Melatonin 3Mg. (W/Chamomile 1Mg.) 60 Ct | The Green HouseMelatonin 3Mg. (W/Chamomile 1Mg.) 60 Ct | The Green House
It features several key, nutraceutical blends. Fo Ti Blast™ (60 mg/cap) features Fo Ti, a premier botanical revered for centuries. Rhodiola Pro Blend™ delivers the famous 3 Rs: Rhaponticum, Rhodiola Rosea and Rhodiola Crenulata (70 mg/cap), the perfect adaptogenic triple blend. Ecko-Boost™ showcases the amazing nutritional star, Ecklonia Cava (55 mg/cap), and Nopal Pro Blend™ (190 mg/cap) is also included for optimal effect. ...
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Enogen® Corn Hybrids Good for Feed and Fuel | AnimalEnogen® Corn Hybrids Good for Feed and Fuel | Animal
Enogen® corn hybrids from Syngenta have been providing value for farmers and ethanol producers, now Enogen® Feed hybrids can help provide value for beef and dairy producers as well. Enogen continues to be an exciting part of our business in Syngenta and the NK brand, said Quinn Showalter, NK Sales Head, during an interview at the National Association of Farm Broadcasting (NAFB) annual Trade Talk. Enogen corn will produce about 2 billion gallons of ethanol this year. New as we move forward into 2018 is the value that Enogen brings from a feed standpoint.. Showalter says on-farm trials this year showed very promising results and as grain or silage, can provide a valuable ration component that helps provide more available energy for cattle in the form of starch and sugar, which also helps improve digestibility. There is incremental value in the form of feed efficiency that come from Enogen, he said.. In this interview, Quinn also discusses Syngentas long-term commitment to the NK brand and ...
http://animal.agwired.com/2017/11/21/enogen-corn-hybrids-good-for-feed-and-fuel/
Active transport of organic acids in the proximal tubules of the surviving rat kidney normally and under various influences. II...Active transport of organic acids in the proximal tubules of the surviving rat kidney normally and under various influences. II...
Exogenous cyclic 3,5-AMP (cAMP) and substances known to increase the intracellular concentration of this nucleotide (isoproterenol, theophylline, noradrenaline, lactate) were shown to inhibit the transport of fluorescein (a weak organic acid) into the rat renal proximal tubules at 20 degrees C. Carbacholine decreasing intracellular cAMP concentration stimulated the transport. Propranolol, a beta-adrenergic blockator, diminished significantly the inhibitory effect of noradrenaline on the transport. Lactate and carbacholine when added simultaneously, neutralize their action. The inhibitory action of intracellular cAMP on the transport is supposed to be a result of the diminition of a pool of endogenous weak organic acids which may take part in the exchange of diffusion with the marker anion across basal plasma membrane.
https://www.semanticscholar.org/paper/Active-transport-of-organic-acids-in-the-proximal-Bresler-Nikiforov/82da9eb4db80275848290416cd35bdcea6db2843
Author: You, J. F. / Publication Year: 2010 / Subject: aluminum / Text Availability: Citation in PubAg - PubAg Search ResultsAuthor: You, J. F. / Publication Year: 2010 / Subject: aluminum / Text Availability: Citation in PubAg - PubAg Search Results
To further understand the process of Al-induced citrate secretion from soybean roots, the effect of protein synthesis inhibitor, anion channel blockers, and citrate carrier inhibitors on Al-induced citrate exudation was investigated in Al-resistant soybean cultivar PI 416937. Citrate exudation from roots increased with the increase of Al concentration from 10 to 50 μM and initiated after 4 h of Al ...
https://pubag.nal.usda.gov/?f%5Bpublication_year_rev%5D%5B%5D=7990-2010&f%5Bsubject_term%5D%5B%5D=aluminum&f%5Btext_availability%5D%5B%5D=Citation+in+PubAg&per_page=20&q=%22You%2C+J.+F.%22&search_field=author&sort=date-asc
Author: You, J. F. / Publication Year: 2010 / Subject: Glycine max and aluminum - PubAg Search ResultsAuthor: You, J. F. / Publication Year: 2010 / Subject: Glycine max and aluminum - PubAg Search Results
To further understand the process of Al-induced citrate secretion from soybean roots, the effect of protein synthesis inhibitor, anion channel blockers, and citrate carrier inhibitors on Al-induced citrate exudation was investigated in Al-resistant soybean cultivar PI 416937. Citrate exudation from roots increased with the increase of Al concentration from 10 to 50 μM and initiated after 4 h of Al ...
https://pubag.nal.usda.gov/?f%5Bpublication_year_rev%5D%5B%5D=7990-2010&f%5Bsubject_term%5D%5B%5D=Glycine+max&f%5Bsubject_term%5D%5B%5D=aluminum&per_page=50&q=%22You%2C+J.+F.%22&search_field=author&sort=date-desc
Bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate - Registration Dossier - ECHABis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate - Registration Dossier - ECHA
According to Regulation (EC) No. 1907/2006, Annex VIII, section 9.2.2.1, column 2, the study need not be conducted if the substance is highly insoluble in water or the substance is readily biodegradable. The water solubility of the test substance is 47 µg/L at 20 °C and is therefore classed as insoluble. Furthermore a Ready Biodegradability test shows 54.1% degradation after 28 days. Although this does not fulfill the minimum criteria set out by the OECD method, it does however indicate that the material achieved ,50 % within 30 days, highlighting its propensity for biodegradation. An inherent biodegradability test shows 80.5% degradation after 28 days, therefore it is considered that the material is inherently biodegradable and as such not persistent in environmentally significant conditions. Therefore given the poor solubility and propensity for biodegradation further studies are scientifically unjustified. ...
https://www.echa.europa.eu/web/guest/registration-dossier/-/registered-dossier/12795/5/2/3
Team - Helmholtz-Zentrum für Umweltforschung UFZTeam - Helmholtz-Zentrum für Umweltforschung UFZ
We are happy to welcome our new PhD student Flora Allendorf. Floras project toxicokinetic modeling of perfluoroalkyl acids (PFAAs) in humans is a PhD project of IP Exposom.. Additionally, we now are happy to welcome our PhD student Andrea Ebert here in Leipzig, who spent her first year of PhD in a cooperating group in Linz. Andrea investigates the membrane permeability of ionic and neutral species. ...
https://www.ufz.de/index.php?de=39187
ChemIDplus - 87607-27-0 - FIFBPQMPYUTVAO-UHFFFAOYSA-N - Carbamic acid, (5-amino-1,2-dihydro-3-(((4-methoxyphenyl)methylamino...ChemIDplus - 87607-27-0 - FIFBPQMPYUTVAO-UHFFFAOYSA-N - Carbamic acid, (5-amino-1,2-dihydro-3-(((4-methoxyphenyl)methylamino...
87607-27-0 - FIFBPQMPYUTVAO-UHFFFAOYSA-N - Carbamic acid, (5-amino-1,2-dihydro-3-(((4-methoxyphenyl)methylamino)methyl)-2-methylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester - Similar structures search, synonyms, formulas, resource links, and other chemical information.
https://chem.nlm.nih.gov/chemidplus/rn/87607-27-0
The acidic reactions of ethanoic acid- Learn ChemistryThe acidic reactions of ethanoic acid- Learn Chemistry
Acids are an important group of chemicals. Organic acids are characterised by the presence of a -COOH group attached to a carbon atom. In this experiment, some typical properties of a weak organic acid are observed.
http://www.rsc.org/learn-chemistry/resource/res00000462/the-acidic-reactions-of-ethanoic-acid?cmpid=CMP00005925
Plus itPlus it
The inhibition of root growth by aluminum (Al) is well established, yet a unifying mechanism for Al toxicity remains unclear. The association between cell growth and endogenously generated ionic currents measured in many different systems, including plant roots, suggests that these currents may be directing growth. A vibrating voltage microelectrode system was used to measure the net ionic currents at the apex of wheat (Triticum aestivum L.) roots from Al-tolerant and Al-sensitive cultivars. We examined the relationship between these currents and Al-induced inhibition of root growth. In the Al-sensitive cultivar, Scout 66, 10 micromolar Al (pH 4.5) began to inhibit the net current and root elongation within 1 to 3 hours. These changes occurred concurrently in 75% of experiments. A significant correlation was found between current magnitude and the rate of root growth when data were pooled. No changes in either current magnitude or growth rate were observed in similar experiments using the ...
http://www.plantphysiol.org/content/99/3/1193
Phenomenex HPLC Application #14969: Monosaccharides with organic acids using Rezex ROAPhenomenex HPLC Application #14969: Monosaccharides with organic acids using Rezex ROA
HPLC Application #14969: Monosaccharides with organic acids using Rezex ROA. Column used: Rezex™ ROA-Organic Acid H+ (8%), LC Column 300 x 7.8 mm, Ea Part#: 00H-0138-K0
http://www.phenomenex.com/Application/Detail/14969
Organic Acids and bases - Organic Acids and Bases This document has been written to provide you with an overview of the...Organic Acids and bases - Organic Acids and Bases This document has been written to provide you with an overview of the...
View Notes - Organic_Acids_and_bases from CHEM CHEM266 at Waterloo. Organic Acids and Bases This document has been written to provide you with an overview of the fundamental concepts of organic
https://www.coursehero.com/file/6016990/Organic-Acids-and-bases/
ST066911AC | bioactive-compounds | chemical-compoundsST066911AC | bioactive-compounds | chemical-compounds
Formula: C14H24N2O7MW: 332. 35Salt: 2HClCAS: 22189-32-8TNP NUMBER: TNP00199MDL NUMBER: MFCD00058104IUPAC: (8S,11S,13S,14S,3R,6R,10R,12R)-12,14-bis(methylamino)-3,11,13-trihydroxy-6-met hyl-2,7,9-trioxatricyclo[8....
http://www.timtec.net/chemical-compounds/bioactive-compounds/st066911ac.html
IodolactonizationIodolactonization
Bartlett, P. A.; Myerson, J. (1978). "Stereoselective epoxidation of acyclic olefinic carboxylic acids via iodolactonization". ... 6-heptadien-4-carboxylic acid derivatives". Tetrahedron Letters. 29 (13): 1517. doi:10.1016/S0040-4039(00)80340-8. Baldwin, ... mechanism involves the formation of a positively charged halonium ion in a molecule that also contains a carboxylic acid (or ...
https://en.wikipedia.org/wiki/Iodolactonization
Protecting groupProtecting group
Removed by acid. Normally, the cleavage of acyclic acetals is easier than of cyclic acetals. Acylals - Removed by Lewis acids. ... Protection of carboxylic acids: Methyl esters - Removed by acid or base. Benzyl esters - Removed by hydrogenolysis. tert-Butyl ... Methylthiomethyl ether - Removed by acid. Pivaloyl (Piv) - Removed by acid, base or reductant agents. It is substantially more ... Silyl esters - Removed by acid, base and organometallic reagents. Orthoesters - Removed by mild aqueous acid to form ester, ...
https://en.wikipedia.org/wiki/Protecting_group
Mizoroki-Heck vs. Reductive HeckMizoroki-Heck vs. Reductive Heck
"Enantioselective Redox-Relay Oxidative Heck Arylations of Acyclic Alkenyl Alcohols using Boronic Acids". Journal of the ... In the conjugate addition case, intermediate 34 can be intercepted with formic acid to form a palladium complex (35) that can ... however acyclic internal alkenes were poor substrates for the reaction in terms of yield and regioselectivity. Unique to this ... and formic acid additive. Under these conditions, the conjugate addition product is formed preferentially to the vinylic ...
https://en.wikipedia.org/wiki/Mizoroki-Heck_vs._Reductive_Heck
Glycol nucleic acidGlycol nucleic acid
Synthesis of acyclic oligonucleotides as antiviral and antiinflammatory agents and inhibitors of phospholipase A2. PCT Int. ... Glycol nucleic acid (GNA) is a polymer similar to DNA or RNA but differing in the composition of its "backbone". GNA is not ... Zhang L, Peritz A, Meggers E (March 2005). "A simple glycol nucleic acid". Journal of the American Chemical Society. 127 (12): ... It is possibly the simplest of the nucleic acids, making it a hypothetical precursor to RNA. ...
https://en.wikipedia.org/wiki/GNA_
Adenylate kinase 1Adenylate kinase 1
"Acyclic phosphonate nucleotides and human adenylate kinases: impact of a borano group on alpha-P position". Nucleosides ... Nucleotides Nucleic Acids. 27 (4): 319-31. doi:10.1080/15257770801941952. PMID 18404568. S2CID 23819055. Gloria-Bottini F, ...
https://en.wikipedia.org/wiki/Adenylate_kinase_1
PederinPederin
Here, pederic acid is added to the protected compound in LiHMDS and THF, producing a 75% yield. The protecting groups are then ... introducing stereoselective reduction of the acyclic ketone. Michael addition of nitromethane is performed. After several steps ... Beginning with (+)-benzoylselenopederic acid, Zn(BH4)2 reduction is applied, ... 2. Stereocontrolled synthesis of (+)-benzoylselenopederic acid and total synthesis of (+)-pederin". Tetrahedron Letters. 26 (52 ...
https://en.wikipedia.org/wiki/Pederin
SulfonamideSulfonamide
The related sulfinamides (R(S=O)NHR) are amides of sulfinic acids (R(S=O)OH) (see sulfinyl). Chiral sulfinamides such as tert- ... Hydrochlorothiazide is a drug that features both acyclic and cyclic sulfonamide groups. Camphorsultam is a sultam used as a ... Sulfonamide (medicine) Sulfamic acid Sulfamide Actor, P.; Chow, A. W.; Dutko, F. J.; McKinlay, M. A. "Chemotherapeutics". ... Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group with an amine group. In ...
https://en.wikipedia.org/wiki/Sulfonamide
PhospheniumPhosphenium
Triflic acid is often used. N-heterocyclic phosphenium (NHP) have also been reported. Reaction of PI3 with the α-diimine yields ... Acyclic phosphenium compounds were synthesized by Fleming's thesis advisor Robert Parry in 1976. Several methods exist for the ... Harrison, James F.; Liedtke, Richard C.; Liebman, Joel F. (1979-11-01). "The multiplicity of substituted acyclic carbenes and ... 1972-10-01). "Synthesis of a cyclic fluorodialkylaminophosphine and its coordination with boron acids. Formation of a unique ...
https://en.wikipedia.org/wiki/Phosphenium
Flippin-Lodge angleFlippin-Lodge angle
L.A. Flippin & C.H. Heathcock (1983) Acyclic stereoselection. 16. High diastereofacial selectivity in Lewis acid mediated ... amino acid side chains in enzyme active sites; see below). Planar electrophiles include aldehydes and ketones, carboxylic acid- ... These nucleophiles can be paired with an array of planar electrophiles: aldehydes and ketones, carboxylic acid-derivatives, and ... Mahrwald, Rainer (1999). "Diastereoselection in Lewis-Acid-Mediated Aldol Additions" (PDF). Chem. Rev. 99 (5): 1095-1120, esp. ...
https://en.wikipedia.org/wiki/Flippin–Lodge_angle
Organostannane additionOrganostannane addition
2) This is not the case in Lewis-acid-promoted reactions, in which either the (Z)- or (E)-stannane affords the syn product ... and depends on the relative energies of a number of acyclic transition states. (E)-Stannanes exhibit higher syn selectivity ... Lewis acid promoted and transmetalation reactions are much milder and have achieved synthetic utility. Intramolecular addition ... Chelation control using Lewis acids such as magnesium bromide can lead to high stereoselectivities for reactions of α-alkoxy ...
https://en.wikipedia.org/wiki/Organostannane_addition
Acetalated dextranAcetalated dextran
During the synthesis of acetalated dextran both acyclic and cyclic acetals are formed. The acyclic acetals degrade into an ... This allows it to be processed in the same manner as many polyesters, like poly(lactic-co-glycolic acid), through processes ... The ratio of cyclic to acyclic acetals varies with reaction time since acyclic acetals are kinetically favored and cyclic ... "Acid-Degradable and Bioerodible Modified Polyhydroxylated Materials". Google Patent. Kauffman, KJ; Do, C; Sharma, S; Gallovic, ...
https://en.wikipedia.org/wiki/Acetalated_dextran
Colobopsis saundersiColobopsis saundersi
6R)-(E)-2,6-Dimethyl-2-octen-1,8-dionic acid is an acyclic monoterpene previously undocumented in insects. However, the ... Terpenoids Citronellal Citronellol Citronellic acid Isopulegol (6R)-(E)-2,6-Dimethyl-2-octen-1,8-dionic acid Both 2,4- ...
https://en.wikipedia.org/wiki/Colobopsis_saundersi
WoodWood
... isopimaric acid, abietic acid, levopimaric acid, palustric acid, neoabietic acid and dehydroabietic acid. Bicyclic resin acids ... acyclic polyterpenoids). The mono- and sesquiterpenes of the softwood are responsible for the typical smell of pine forest. ... Resin acids are usually tricyclic terpenoids, examples of which are pimaric acid, sandaracopimaric acid, ... are also found, such as lambertianic acid, communic acid, mercusic acid and secodehydroabietic acid. Cycloartenol, betulin and ...
https://en.wikipedia.org/wiki/Wood
Apache HiveApache Hive
Recent version of Hive 0.14 had these functions fully added to support complete ACID properties. Hive 0.14 and later provides ... Internally, a compiler translates HiveQL statements into a directed acyclic graph of MapReduce, Tez, or Spark jobs, which are ... ISBN 978-1-4493-8973-4. Hive Language Manual ACID and Transactions in Hive "Hive A Warehousing Solution Over a MapReduce ... Support for insert, update, and delete with full ACID functionality was made available with release 0.14. ...
https://en.wikipedia.org/wiki/Apache_Hive
ThiosulfinateThiosulfinate
... related thiosulfinates show radical-trapping antioxidant activity associated with easy formation of sulfenic acids The acyclic ... The thiosulfinate group can occur in cyclic as well as acyclic structures. A variety of acyclic and cyclic thiosulfinates are ... Methyl methanethiosulfinate decomposes thermally giving methanesulfenic acid (CH3SOH), the simplest sulfenic acid, as well as ... Asparagusic acid S-oxide and brugierol are other natural 1,2-dithiolane-1-oxides occurring in Asparagus officinalis and ...
https://en.wikipedia.org/wiki/Thiosulfinate
Baeyer-Villiger oxidationBaeyer-Villiger oxidation
4-nitroperbenzoic acid > mCPBA and performic acid > peracetic acid > hydrogen peroxide > tert-butyl hydroperoxide. The ... The migrating group in acyclic ketones, usually, is not 1° alkyl group. However, they may be persuaded to migrate in preference ... some of the more common oxidants include meta-chloroperbenzoic acid (mCPBA) and trifluoroperacetic acid (TFPAA). The general ... Benzeneseleninic acid derivatives as catalysts have been reported to give high selectivity with hydrogen peroxide as the ...
https://en.wikipedia.org/wiki/Baeyer–Villiger_oxidation
Penelope BrothersPenelope Brothers
"Decarboxylation of an α-amino acid coordinated to cobalt (III): kinetic stabilisation and molecular structure of a Co-C-N three ... pendant-arm macrocyclic and acyclic ligands." Inorganic Chemistry 36, no. 24 (1997): 5470-5477. Brothers, Penelope J., and ... "Condensation reactions of cobalt amino acid complexes with formaldehyde: Preparation and crystal structures of cobalt complexes ...
https://en.wikipedia.org/wiki/Penelope_Brothers
Saegusa-Ito oxidationSaegusa-Ito oxidation
For acyclic substrates the reaction yields the thermodynamic E-olefin product exclusively. This discovery was preceded nearly ... yields the palladium hydride enone complex which upon reductive elimination yields the product along with acetic acid and Pd0. ... The reversibility of the elimination step allows equilibration, leading to the thermodynamic E-selectivity in acyclic ... Qiang Tu's synthesis of the Alzheimer's disease medication galantamine likewise used this reaction in the presence of an acid- ...
https://en.wikipedia.org/wiki/Saegusa–Ito_oxidation
Donna NelsonDonna Nelson
"Correlation of Relative Rates of Chromyl Chloride Oxidation and Chromic Acid Oxidation of Acyclic Alkenes Versus Alkene IPs and ... Nelson, Donna J.; Li, R.; Brammer, C. "The Correlation of Relative Rates of PdCl2 Oxidation of Functionalized Acyclic Alkenes ... Nelson, Donna J.; Li, Ruibo; Brammer Christopher N. "Substituent Effects in Acid-Catalyzed Hydration of Alkenes, Measured Under ... "The Use of Relative Magnitudes of Steric Effects to Explore Reactions of Molecular Halogens with Representative Acyclic Alkenes ...
https://en.wikipedia.org/wiki/Donna_Nelson
H. V. ThulasiramH. V. Thulasiram
Isolation and purification of shikimic acid from plant sources and Microbial chiral resolution of cyclic and acyclic acetates ... Mevalonate pathway Shikimic acid India portal Biology portal Chemistry portal Please see Selected bibliography section " ... "A process of chiral resolution of cyclic and acyclic acetates to enantiomerically pure (r)--alcohols". Google Patents. 15 May ...
https://en.wikipedia.org/wiki/H._V._Thulasiram
Aldol reactionAldol reaction
When an acid catalyst is used, the initial step in the reaction mechanism involves acid-catalyzed tautomerization of the ... Heathcock, C. H.; Buse, C. T.; Kleschnick, W. A.; Pirrung, M. C.; Sohn, J. E.; Lampe, J. (1980). "Acyclic stereoselection. 7. ... Bal, B.; Buse, C. T.; Smith, K.; Heathcock, C. H., (2SR,3RS)-2,4-Dimethyl-3-Hydroxypentanoic Acid, Org. Synth., Coll. Vol. 7, p ... The acid also serves to activate the carbonyl group of another molecule by protonation, rendering it highly electrophilic. The ...
https://en.m.wikipedia.org/wiki/Aldol_reaction
Imine Diels-Alder reactionImine Diels-Alder reaction
4) In many cases, cyclic dienes give higher diastereoselectivities than acyclic dienes. Use of amino-acid-based chiral ... Cyclic, acyclic, and tethered imines have all been employed in the reaction with success. (1) Simple alkyl or aryl amines are ... The lowest-energy transition state for the concerted process places the imine lone pair (or coordinated Lewis acid) in an exo ... 2) When the imine nitrogen is protonated or coordinated to a strong Lewis acid, the mechanism shifts to a stepwise, Mannich- ...
https://en.wikipedia.org/wiki/Imine_Diels–Alder_reaction
Ketene cycloadditionKetene cycloaddition
5) Cyclic and acyclic dienes generally give cyclobutanones, rather than Diels-Alder adducts. In reactions of cyclic dienes, the ... Lewis acid catalysis is necessary for this process, unless the carbonyl compound possesses strongly electron- withdrawing ...
https://en.wikipedia.org/wiki/Ketene_cycloaddition
AziridinesAziridines
Aziridine is less basic than acyclic aliphatic amines, with a pKa of 7.9 for the conjugate acid, due to increased s character ... N-unsubstituted aziridines can be opened with olefins in the presence of strong Lewis acid B(C 6F 5) 3. As electrophiles, ... CH 2-CH+ 2-R This reaction type requires a Lewis acid catalyst such as boron trifluoride. In this way 2-phenyl-N-tosylaziridine ...
https://en.wikipedia.org/wiki/Aziridines
AziridineAziridine
... is less basic than acyclic aliphatic amines, with a pKa of 7.9 for the conjugate acid, due to increased s character ...
https://en.wikipedia.org/wiki/Aziridine
Sodium trimetaphosphateSodium trimetaphosphate
It is the sodium salt of trimetaphosphoric acid. It is a colourless solid that finds specialised applications in food and ... Hydrolysis of the ring leads to the acyclic sodium triphosphate: Na3P3O9 + H2O → H2Na3P3O10 The main reactions of the ... "Phosphoric Acid and Phosphates". Ullmann's Encyclopedia of Industrial Chemistry. Ullmann's Encyclopedia of Industrial Chemistry ...
https://en.wikipedia.org/wiki/Sodium_trimetaphosphate
Persistent carbenePersistent carbene
The first acyclic persistent carbene was reported in 1996, thus showing that a cyclic backbone was not necessary for their ... NHCs are often strongly basic (the pKa value of the conjugate acid of an imidazol-2-ylidene was measured at ca. 24) and react ... These acyclic carbenes have diagnostic 13C NMR chemical shift values between 250 and 300 ppm for the carbenic carbon, further ... Unlike the cyclic derivatives, the acyclic carbenes are flexible with respect to rotation of the bonds to the carbenic atom. By ...
https://en.wikipedia.org/wiki/Persistent_carbene
BenzotriyneBenzotriyne
Theoretical study of acyclic and cyclic cumulenes and acetylenes". Journal of Molecular Structure: THEOCHEM. 313 (3): 335-349. ... Fields, Ellis K.; Meyerson, Seymour (October 1966). "Arynes by Pyrolysis of Acid Anhydrides". J. Org. Chem. 31 (10): 3307-3309 ...
https://en.wikipedia.org/wiki/Benzotriyne
Step-growth polymerizationStep-growth polymerization
If no acid catalyst is added, the reaction will still proceed because the acid can act as its own catalyst. The rate of ... It is not always water that is released in step-growth polymerization: in acyclic diene metathesis or ADMET dienes polymerize ... The simple esterification is an acid-catalyzed process in which protonation of the acid is followed by interaction with the ... The first stage forms a soluble and fusible high-molecular-weight poly(amic acid) in a polar aprotic solvent such as NMP or N,N ...
https://en.wikipedia.org/wiki/Step-growth_polymerization
Benzhydryl compoundsBenzhydryl compounds
Acyclic (3°C): diphenhydramine (c.f deramciclane), orphenadrine, p-methyldiphenhydramine. *Acyclic (4°C): moxastine, Clemastine ... Alkylamine: A-86929, amfonelic acid. Benzenes linked by a non-carbon atom[edit]. *Nitrogen: promethazine, imipramine, ...
https://en.wikipedia.org/wiki/Benzhydryl_compounds
Protoporphyrin IXProtoporphyrin IX
Protoporphyrins are tetrapyrroles containing four methyl, two propionic acid, and two vinyl side chains. The number (e.g. IX) ... The simplified biosynthetic sequence is acyclic precursors → mono-pyrrole (porphobilinogen) → tetrapyrrole, also known as a ...
https://en.wikipedia.org/wiki/Ferriprotoporphyrin
Gene ontologyGene ontology
"Nucleic Acids Research. 36 (Web Server issue): W368-71. doi:10.1093/nar/gkn256. PMC 2447766. PMID 18480123.. ... The GO ontology is structured as a directed acyclic graph, and each term has defined relationships to one or more other terms ... "Nucleic Acids Research. 36 (Database issue): D440-4. doi:10.1093/nar/gkm883. PMC 2238979. PMID 17984083.. ... "Nucleic Acids Research. 36 (10): 3420-35. doi:10.1093/nar/gkn176. PMC 2425479. PMID 18445632.. ...
https://en.wikipedia.org/wiki/Gene_ontology
Mass spectral interpretationMass spectral interpretation
There are five types of carbonyl compounds, including aldehydes, ketones, carboxylic acids and esters.[2] The principal ... Most possible ionization mechanism of acyclic alkenes. McLafferty-like rearrangements are possible (similar to carbonyl pi ... or acid and so on). For alcohols, this heterolytic cleavage releases a water molecule. Since the charge-site reactions are ...
https://en.wikipedia.org/wiki/Mass_spectrum_analysis
Amino acidAmino acid
... acyclic, aromatic, conteenin hydroxyl or sulfur, etc.). In the form o proteins, amino acid residues form the seicont-lairgest ... Amino acids are biologically important organic compoonds componed o amine (-NH2) an carboxylic acid (-COOH) functional groups, ... alang wi a side-cheen specific tae ilk amino acid.[1][2][3] The key elements o an amino acid are caurbon, hydrogen, oxygen, an ... Aboot 500 amino acids are kent (tho anerly 20 appear in the genetic code) an can be clessifee'd in mony weys.[4] Thay can be ...
https://sco.wikipedia.org/wiki/Amino_acid
Click chemistryClick chemistry
Both tetrazoles and the alkene groups have been incorporated as protein handles as unnatural amino acids, but this benefit is ... Moreover, substitution on both the carbon and nitrogen atoms of the nitrone dipole, and acyclic and endocyclic nitrones are all ... Challenges include the presence of endogenous alkenes, though usually cis (as in fatty acids) they can still react with the ... The development of unnatural amino acid incorporation by ribosomes has allowed for the incorporation of click reaction partners ...
https://en.wikipedia.org/wiki/Click_chemistry
Conservation and restoration of bone, horn, and antler objectsConservation and restoration of bone, horn, and antler objects
... using an acid-free tray is highly recommended. These objects can also be protected further by being wrapped in unbuffered, acid ... Attaching items to mounts is done with padded wires or flat acyclic plastic clips. Metals in direct contact with these organic ... which may chew and attack these materials especially bone acids exposure to strong visible and ultraviolet light which may ...
https://en.wikipedia.org/wiki/Conservation_and_restoration_of_bone,_horn,_and_antler_objects
MonoterpeneMonoterpene
Elimination of the pyrophosphate group from geranyl pyrophosphate leads to the formation of acyclic monoterpenes such as ... which is formed from acetyl-CoA via the intermediacy of mevalonic acid in the HMG-CoA reductase pathway. An alternative, ... Monoterpenes may be linear (acyclic) or contain rings. Modified terpenes, such as those containing oxygen functionality or ... Hydrolysis of the phosphate groups leads to the prototypical acyclic monoterpenoid geraniol. Additional rearrangements and ...
https://en.m.wikipedia.org/wiki/Monoterpenes
Cis-trans isomerismCis-trans isomerism
One example of this is the relationship between oleic acid and elaidic acid; oleic acid, the cis isomer, has a melting point of ... Usually for acyclic systems trans isomers are more stable than cis isomers. This is typically due to the increased unfavorable ... The cis isomer is called maleic acid and the trans isomer fumaric acid. Polarity is key in determining relative boiling point ... The two isomers of butenedioic acid have such large differences in properties and reactivities that they were actually given ...
https://en.m.wikipedia.org/wiki/Cis-trans_isomerism
AromaticityAromaticity
The four aromatic amino acids histidine, phenylalanine, tryptophan, and tyrosine each serve as one of the 20 basic building- ... Wiberg, Kenneth B. (1990). "Resonance interactions in acyclic systems. 2. Y-Conjugated anions and cations". J. Am. Chem. Soc. ... Examples include trinitrotoluene (TNT), acetylsalicylic acid (aspirin), paracetamol, and the nucleotides of DNA. Aromatic ... "On Insolinic Acid". Proceedings of the Royal Society. 8: 1-3. doi:10.1098/rspl.1856.0002. "Bonding in benzene - the Kekulé ...
https://en.wikipedia.org/wiki/Aromaticity
WarfarinWarfarin
The precursors of these factors require gamma carboxylation of their glutamic acid residues to allow the coagulation factors to ... Acyclic tautomer (left) and cyclic hemiketal tautomer (right). X-ray crystallographic studies of warfarin show that it exists ... When this occurs, the coagulation factors are no longer carboxylated at certain glutamic acid residues, and are incapable of ... The enzyme that carries out the carboxylation of glutamic acid is gamma-glutamyl carboxylase. The carboxylation reaction will ...
https://en.m.wikipedia.org/wiki/Warfarin
CholecalciferolCholecalciferol
Acyclic (linear, cis and trans forms). *Monocyclic (single ring). *Bicyclic (2 rings) ... Resin acids. *Abietic acid. *Communic acid. *Dehydroabietic acid. *Isopimaric acid. *Lambertianic acid ...
https://en.wikipedia.org/wiki/Cholecalciferol
Multiple sequence alignmentMultiple sequence alignment
"Nucleic Acids Res. 43 (W1): W3-6. doi:10.1093/nar/gkv310. PMC 4489230. PMID 25855806.. ... Typical HMM-based methods work by representing an MSA as a form of directed acyclic graph known as a partial-order graph, which ... "Nucleic Acids Res. 22 (22): 4673-80. doi:10.1093/nar/22.22.4673. PMC 308517. PMID 7984417.. ... "Nucleic Acids Res. 19 (23): 6565-72. doi:10.1093/nar/19.23.6565. PMC 329220. PMID 1754394.. ...
https://en.wikipedia.org/wiki/Multiple_Sequence_Alignment
Heterocyclic compoundHeterocyclic compound
1832: Dobereiner produces furfural (a furan) by treating starch with sulfuric acid. 1834: Runge obtains pyrrole ("fiery oil") ... The saturated heterocycles behave like the acyclic derivatives. Thus, piperidine and tetrahydrofuran are conventional amines ... Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related ...
https://en.wikipedia.org/wiki/Heterocyclic_ring
Functional groupFunctional group
Carboxylic acid Carboxyl. RCOOH carboxy-. -oic acid Acetic acid. (Ethanoic acid) Ester. Carboalkoxy RCOOR' alkanoyloxy-. or. ... "RC-81.1.1. Monovalent radical centers in saturated acyclic and monocyclic hydrocarbons, and the mononuclear EH4 parent hydrides ... Sulfinic acid. Sulfino RSO2H sulfino-. (-SO2H) -sulfinic acid 2-Aminoethanesulfinic acid ... Sulfonic acid. Sulfo RSO3H sulfo-. (-SO3H) -sulfonic acid Benzenesulfonic acid ...
https://en.m.wikipedia.org/wiki/Functional_group
Juvenile hormoneJuvenile hormone
... then it is methylated by a JH acid methyl transferase In most orders, farnesoic acid is methylated by farensoic acid methyl ... Juvenile hormones (JHs) are a group of acyclic sesquiterpenoids that regulate many aspects of insect physiology. JHs regulate ... JH esterase cleaves the methyl ester giving JH acid. JH acid is attached by JH epoxide hydrolase, which converts the epoxide ... In Lepidoptera and mosquitoes farnesoic acid or its homologs is epoxidized by a P450 dependent farnesoic acid methyl epoxidase ...
https://en.wikipedia.org/wiki/Juvenile_hormone
Cis-trans isomerismCis-trans isomerism
One example of this is the relationship between oleic acid and elaidic acid; oleic acid, the cis isomer, has a melting point of ... Usually for acyclic systems trans isomers are more stable than cis isomers. This is typically due to the increased unfavourable ... Oleic acid. Elaidic acid. These differences can be very small, as in the case of the boiling point of straight-chain alkenes, ... The cis isomer is called maleic acid and the trans isomer fumaric acid. Polarity is key in determining relative boiling point ...
https://en.wikipedia.org/wiki/Cis-trans_isomerism
PhytosteroidPhytosteroid
Dihydroxybenzoic acids. *2,3-Dihydroxybenzoic acid (Hypogallic acid). *2,4-Dihydroxybenzoic acid ... Acyclic (linear, cis and trans forms). *Monocyclic (single ring). *Bicyclic (2 rings) ...
https://en.wikipedia.org/wiki/Phytosteroid
LimoneneLimonene
... occurs commonly as the D- or (R)-enantiomer, but racemizes to dipentene at 300 °C. When warmed with mineral acid, ... Acyclic (linear, cis and trans forms). *Monocyclic (single ring). *Bicyclic (2 rings) ... In another synthetic method Markovnikov addition of trifluoroacetic acid followed by hydrolysis of the acetate gives terpineol ...
https://en.wikipedia.org/wiki/Dipentene
CholecalciferolCholecalciferol
Acyclic (linear, cis and trans forms). *Monocyclic (single ring). *Bicyclic (2 rings) ...
https://en.wikipedia.org/wiki/Vitamin_D3
List of Apache Software Foundation projectsList of Apache Software Foundation projects
Omid: flexible, reliable, high performant and scalable ACID transactional framework. *PageSpeed: series of open source ... Tez is an effort to develop a generic application framework which can be used to process arbitrarily complex directed-acyclic ...
https://en.wikipedia.org/wiki/List_of_Apache_Software_Foundation_projects
SubstituentSubstituent
... if there is a carboxylic acid called "X-ic acid", an alcohol ending "X-anol" (or "X-yl alcohol"), or an alkane called "X-ane", ... "recommended only for saturated acyclic and monocyclic hydrocarbon substituent groups and for the mononuclear parent hydrides of ... In proteins, side chains are attached to the alpha carbon atoms of the amino acid backbone. ...
https://en.wikipedia.org/wiki/Substituent
BiochemistryBiochemistry
The most common nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).[48] The phosphate group and the sugar ... A monosaccharide can switch between acyclic (open-chain) form and a cyclic form. The open-chain form can be turned into a ring ... keto acid. Enzymes called transaminases can easily transfer the amino group from one amino acid (making it an α-keto acid) to ... An amino acid consists of a carbon atom attached to an amino group, -NH2, a carboxylic acid group, -COOH (although these exist ...
https://en.wikipedia.org/wiki/Biochem
Dietary fiberDietary fiber
Short-chain fatty acids[edit]. When fermentable fiber is fermented, short-chain fatty acids (SCFA) are produced. SCFAs are ... Acyclic (linear, cis and trans forms). *Monocyclic (single ring). *Bicyclic (2 rings) ... Almost all of these short-chain fatty acids will be absorbed from the colon. This means that fecal short-chain fatty acid ... The production of short-chain fatty acids has several possible actions on the gut mucosa. All of the short-chain fatty acids ...
https://en.wikipedia.org/wiki/Dietary_fibre
Naturally occurring phenolsNaturally occurring phenols
Phenolic acids, Phenolic aldehydes Gallic, salicylic acids 8 C6-C2 1 Acetophenones, Tyrosine derivatives, Phenylacetic acids 3- ... Acyclic (linear, cis and trans forms). *Monocyclic (single ring). *Bicyclic (2 rings) ... Homogentisic acid 9 C6-C3 1 Hydroxycinnamic acids, Phenylpropenes, Coumarins, Isocoumarins, Chromones Caffeic, ferulic acids, ... Phenolic acids can be found in mushroom basidiomycetes species.[46] For example, protocatechuic acid and pyrocatechol are found ...
https://en.wikipedia.org/wiki/Natural_phenol
Organosulfur compoundsOrganosulfur compounds
Thiocarboxylic acids and thioamides[edit]. Thiocarboxylic acids (RC(O)SH) and dithiocarboxylic acids (RC(S)SH) are well known. ... García Ruano, J. L.; Cid, M. B.; Martín Castro, A. M.; Alemán, J. (2008). "Acyclic S,S-Dialkylsulfimides". In Kambe, N. (ed.). ... Sulfonic acids like trifluoromethanesulfonic acid is a frequently used reagent in organic chemistry. Sulfinic acids have ... Sulfonic acids have functionality R−S(=O)2−OH.[20] They are strong acids that are typically soluble in organic solvents. ...
https://en.wikipedia.org/wiki/Organosulfur_compound
Cannabinoid receptor antagonistCannabinoid receptor antagonist
Acyclic derivative (Taranabant) CB1 receptor antibodiesEdit. Antibodies of the CB1 receptor have been developed and introduced ... The lipophilic piperidinyl moiety fits nicely in a cavity formed by the amino acid residues Val196/Phe170/Leu387 and Met384 ( ... Acyclic analogs have also been reported. These analogs contain a 1,2-diaryl motif which corresponds to the 1,5-diaryl ... Putative CB1 receptor amino acid side chain residues in receptor-ligand interaction are shown. Rimonabant is taken as a ...
https://en.m.wikipedia.org/wiki/Discovery_and_development_of_Cannabinoid_Receptor_1_Antagonists
Acyclic nucleotide analogues based on phosphonic acids]. | Sigma-AldrichAcyclic nucleotide analogues based on phosphonic acids]. | Sigma-Aldrich
Acyclic nucleotide analogues based on phosphonic acids].. [E V Efimtseva, S N Mikhaĭlov, M V Fomicheva, S V Meshkov, M S ... The synthesis of novel nucleotide analogues on the basis of ethylphosphonic acid was described. A rigid structural element, an ...
https://www.sigmaaldrich.com/catalog/papers/9551196
Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma....Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma....
Polyprenoic acid in hepatocellular carcinoma. [N Engl J Med. 1996]. *Prevention of second primary tumors by an acyclic retinoid ... We developed an acyclic retinoid, polyprenoic acid, that inhibits hepatocarcinogenesis in the laboratory and induces ... Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. ... Treatment with polyprenoic acid significantly reduced the incidence of recurrent or new hepatomas. After a median follow-up of ...
https://www.ncbi.nlm.nih.gov/pubmed/8628336?dopt=Abstract
909. Esters/aliphatic acyclic prim. alcohols/branched-chain/aliphatic acyclic acids (WHO Food Additives Series 40)909. Esters/aliphatic acyclic prim. alcohols/branched-chain/aliphatic acyclic acids (WHO Food Additives Series 40)
... saturated aliphatic acyclic branched-chain acids, isobutyric acid, isovaleric acid, 2-methylbutyric acid, and 2-, 3-, and 4- ... c) 2-Methylbutyric acid, 2-methylpentanoic acid, and 4-methylpentanoic acid In general, branched-chain acids with an alpha- ... The daily per capita intake of the branched-chain acids (i.e. isobutyric acid, isovaleric acid, and 2-methylbutyric acid) ... isobutyric acid, isovaleric acid or 2-methylbutyric acid) and corresponding aliphatic acyclic alcohols. Table 2 summarizes the ...
http://www.inchem.org/documents/jecfa/jecmono/v040je13.htm
Highly stable triple helix formation by homopyrimidine (l)-acyclic threoninol nucleic acids with single stranded DNA and RNA -...Highly stable triple helix formation by homopyrimidine (l)-acyclic threoninol nucleic acids with single stranded DNA and RNA -...
... threoninol nucleic acid (aTNA) containing thymine, cytosine and adenine nucleobases were synthesized and shown to form ... Highly stable triple helix formation by homopyrimidine (L)-acyclic threoninol nucleic acids with single stranded DNA and RNA ... Acyclic (L)-threoninol nucleic acid (aTNA) containing thymine, cytosine and adenine nucleobases were synthesized and shown to ... Highly stable triple helix formation by homopyrimidine (L)-acyclic threoninol nucleic acids with single stranded DNA and RNA V ...
http://pubs.rsc.org/en/Content/ArticleLanding/2015/OB/c4ob02328e
911. Esters/branched-chain terpenoid alc./aliphatic acyclic lin./B-C carb. acids (WHO Food Additives Series 40)911. Esters/branched-chain terpenoid alc./aliphatic acyclic lin./B-C carb. acids (WHO Food Additives Series 40)
... carboxylic acids (linear saturated aliphatic acids (C1-C6), isobutyric acid isovaleric acid and 2-ethylbutyric acid) are ... linear saturated aliphatic acids (C1-C6), isobutyric acid, isovaleric acid and 2-ethylbutyric acid). The four terpenoid ... acid is discussed in the monographs on saturated aliphatic acyclic linear primary alcohols aldehydes and acids and on saturated ... fatty acid or amino acid pathways (Voet & Voet, 1990). In general, the component linear saturated carboxylic acids (C1 - C6) ...
http://inchem.org/documents/jecfa/jecmono/v040je15.htm
Acyclic l-threoninol nucleic acid (l-aTNA) with suitable structural rigidity cross-pairs with DNA and RNA - Chemical...Acyclic l-threoninol nucleic acid (l-aTNA) with suitable structural rigidity cross-pairs with DNA and RNA - Chemical...
... acyclicl-threoninol nucleic acid (l-aTNA). l-aTNA formed a more stable duplex with DNA and RNA than either d-aTNA or serinol ... nucleic acid (SNA) as the rigidity of the l-form was more optimal for interaction with natural nucleic acids. ... We report the hybridization properties of a novel artificial nucleic acid: ... We report the hybridization properties of a novel artificial nucleic acid: acyclicL-threoninol nucleic acid (L-aTNA). L-aTNA ...
http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/c4cc09244a
Acyclic polyimides based on dinitriles and dicarboxylic acids, Russian Journal of Applied Chemistry | 10.1134/S1070427210120256...Acyclic polyimides based on dinitriles and dicarboxylic acids, Russian Journal of Applied Chemistry | 10.1134/S1070427210120256...
"Acyclic polyimides based on dinitriles and dicarboxylic acids, Russian Journal of Applied Chemistry" on DeepDyve, the largest ... Acyclic polyimides based on dinitriles and dicarboxylic acids. Acyclic polyimides based on dinitriles and dicarboxylic acids ... Acyclic polyimides based on dinitriles and dicarboxylic acids. Ochirov, B.; Burdukovskii, V.; Mognonov, D. ... lp/springer_journal/acyclic-polyimides-based-on-dinitriles-and-dicarboxylic-acids-253lslzegY ...
https://www.deepdyve.com/lp/springer_journal/acyclic-polyimides-based-on-dinitriles-and-dicarboxylic-acids-253lslzegY
IDEALS @ Illinois: Acyclic Imidate and Thiomidate Normal-Oxides: Nitrones of Esters and Thioesters (alpha-Alkoxynitrones, Alpha...IDEALS @ Illinois: Acyclic Imidate and Thiomidate Normal-Oxides: Nitrones of Esters and Thioesters (alpha-Alkoxynitrones, Alpha...
The reactions of (Z)-N,S-dimethylthiobenzimidate N-oxide, with methylmagnesium bromide and aqueous acid and base were ... Acyclic Imidate and Thiomidate Normal-Oxides: Nitrones of Esters and Thioesters (alpha-Alkoxynitrones, Alpha-Alkylthionitrones ... Acyclic Imidate and Thiomidate Normal-Oxides: Nitrones of Esters and Thioesters (alpha-Alkoxynitrones, Alpha-Alkylthionitrones ... Acyclic Imidate and Thiomidate Normal-Oxides: Nitrones of Esters and Thioesters (alpha-Alkoxynitrones, Alpha-Alkylthionitrones ...
https://www.ideals.illinois.edu/handle/2142/70324
Acyclic beta-amino acid catalyzed asymmetric anti-selective Mannich-type reactionsAcyclic beta-amino acid catalyzed asymmetric anti-selective Mannich-type reactions
... Dziedzic, Pawel Stockholm University, ... The ability of a primary amine containing acyclic beta(3)-amino acids to catalyze direct asymmetric anti-selective Mannich-type ... 1. Amino acid-catalyzed synthesis of amino acid derivatives: Application and semi-synthesis of Paclitaxel, Docetaxel and their ... Open this publication in new window or tab ,,Amino acid-catalyzed synthesis of amino acid derivatives: Application and semi- ...
http://su.diva-portal.org/smash/record.jsf?pid=diva2%3A185815&c=22&searchType=SIMPLE&language=en&query=&af=%5B%5D&aq=%5B%5B%7B%22personId%22%3A%22acr%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
PRIME PubMed | Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2...PRIME PubMed | Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2...
Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4- ... nucleic acids JO - Nucleosides Nucleotides Nucleic Acids VL - 24 IS - 5-7 N2 - Three acyclic nucleoside phosphonates (ANPs) ... Nucleosides, Nucleotides & Nucleic Acids, 24(5-7), 331-41. De Clercq E, et al. Antiviral Potential of a New Generation of ... Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):331-41.. De Clercq, E., Andrei, G., Balzarini, J., Leyssen, P., Naesens, L ...
https://www.unboundmedicine.com/medline/citation/16247948/Antiviral_potential_of_a_new_generation_of_acyclic_nucleoside_phosphonates_the_6_%5B2__phosphonomethoxy_alkoxy%5D_24_diaminopyrimidines_
Acyclic Stereoselective Boron Alkylation Reactions for the Asymmetric Synthesis of β-Substituted α-Amino Acid DerivativesAcyclic Stereoselective Boron Alkylation Reactions for the Asymmetric Synthesis of β-Substituted α-Amino Acid Derivatives
3KD1: Closed Binary Complex Of An Rb69 Gp43 Fingers Domain Mutant Complexed With An Acyclic Gmp Terminated Primer Template Pair3KD1: Closed Binary Complex Of An Rb69 Gp43 Fingers Domain Mutant Complexed With An Acyclic Gmp Terminated Primer Template Pair
"MMDB and VAST+: tracking structural similarities between macromolecular complexes.Nucleic Acids Res. 2014 Jan; 42(Database ...
https://www.ncbi.nlm.nih.gov/Structure/pdb/3KD1
Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2 exports to Qatar |2018Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2 exports to Qatar |2018
In 2018, Top exporters of Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2 to ... HS Code 291529: Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2. Please note ... Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2. 2018. Qatar. 0.22. 5. Kg. ... Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2. 2018. Qatar. 0.08. 11. Kg. ...
https://wits.worldbank.org/trade/comtrade/en/country/All/year/2018/tradeflow/Exports/partner/QAT/product/291529
Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2 exports to Bangladesh |2018Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2 exports to Bangladesh |2018
In 2018, Top exporters of Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2 to ... HS Code 291529: Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2. Please note ... Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2. 2018. Bangladesh. 0.12. 2. ... Acids; saturated acyclic monocarboxylic acids; acetic acid and its salts n.e.s. in item no. 2915.2 imports by country in 2018 ...
https://wits.worldbank.org/trade/comtrade/en/country/All/year/2018/tradeflow/Exports/partner/BGD/product/291529
RCSB PDB - 3N8M: Crystal Structure of the Grb2 SH2 Domain in Complex with An Acyclic Ligand Having the Sequence pYVNVPRCSB PDB - 3N8M: Crystal Structure of the Grb2 SH2 Domain in Complex with An Acyclic Ligand Having the Sequence pYVNVP
Crystal Structure of the Grb2 SH2 Domain in Complex with An Acyclic Ligand Having the Sequence pYVNVP. *DOI: 10.2210/pdb3N8M/ ... Structures of complexes of macrocycle 7 and its acyclic control 8 are similar except for differences in relative orientations ...
https://www.rcsb.org/structure/3N8M
RCSB PDB - 1K0U: Inhibition of S-adenosylhomocysteine Hydrolase by acyclic sugar Adenosine Analogue D-eritadenineRCSB PDB - 1K0U: Inhibition of S-adenosylhomocysteine Hydrolase by 'acyclic sugar' Adenosine Analogue D-eritadenine
The hydrogen bond network around the acyclic sugar moiety indicates that DEA is more tightly connected to the protein than the ... Inhibition of S-adenosylhomocysteine Hydrolase by acyclic sugar Adenosine Analogue D-eritadenine. *DOI: 10.2210/pdb1K0U/pdb ... Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S- ... DEA is an acyclic sugar Ado analogue, and the C2 and C3 have opposite chirality to those of the cyclic sugar Ado inhibitors. ...
https://www.rcsb.org/structure/1K0U
Pure and Applied ChemistryPure and Applied Chemistry
Lewis acids in diastereoselective processes involving acyclic radicals. Guindon, Y. / Guérin, Brigitte / Rancourt, J. / Chabot ...
https://www.degruyter.com/view/j/pac.1996.68.issue-1/issue-files/pac.1996.68.issue-1.xml
The Effect of Acyclic Retinoid on the Metabolomic Profiles of Hepatocytes and Hepatocellular Carcinoma CellsThe Effect of Acyclic Retinoid on the Metabolomic Profiles of Hepatocytes and Hepatocellular Carcinoma Cells
Background/Purpose Acyclic retinoid (ACR) is a promising chemopreventive agent for hepatocellular carcinoma (HCC) that ... Amino acid metabolism Is the Subject Area "Amino acid metabolism" applicable to this article? Yes. No. ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082860
Synthesis of bridged tricyclo[5.2.1.01,5]decanes via nickel-catalyzed asymmetric domino cyclization of enynones | Nature...Synthesis of bridged tricyclo[5.2.1.01,5]decanes via nickel-catalyzed asymmetric domino cyclization of enynones | Nature...
a (Hetero)arylboronic acid scope. b Enynone scope. c Acyclic substrate. d Allenynone substrate. ... d The stoichiometric reaction of Ni(OAc)2.4H2O with boronic acid. e The use of Ni(I) complex in the reaction. ... All of these meta- and ortho-substituted arylboronic acids proceeded smoothly, providing the corresponding products 3ap-3ar in ... Transmetallation of arylboronic acid with the chiral nickel species A (X could be acetate, hydroxide or 2,2,2-trifluoroethoxide ...
https://www.nature.com/articles/s41467-020-15837-1?error=cookies_not_supported&code=171d4787-dbea-4053-aa66-615b18c8e0f0
Quaternary-centre-guided synthesis of complex polycyclic terpenes | NatureQuaternary-centre-guided synthesis of complex polycyclic terpenes | Nature
... scopadulcic acid A12,13 and acutumine14-the development of target-specific approaches as well as multiple functional-group and ... CuH-Catalyzed Regio- and Enantioselective Hydrocarboxylation of Allenes: Toward Carboxylic Acids with Acyclic Quaternary ... Ziegler, F. E. & Wallace, O. B. The total synthesis of (±)-scopadulcic acids A and B and (±)-scopadulciol. J. Org. Chem. 60, ... Kucera, D. J., OConnor, S. J. & Overman, L. E. Total synthesis of (±)-scopadulcic acid A. An illustration of the utility of ...
https://www.nature.com/articles/s41586-019-1179-2?error=cookies_not_supported&code=9afbb339-edfb-4c2d-b034-4e1300226826
Studies on complexation of alkaline earth metal cations with acyclic polyether dicarboxylic acids<...Studies on complexation of alkaline earth metal cations with acyclic polyether dicarboxylic acids<...
Acyclic polyether dicarboxylic acids having butyl and tetradecyl side alkyl chains at the α-position of the carboxylic acid ... "Acyclic polyether dicarboxylic acids having butyl and tetradecyl side alkyl chains at the α-position of the carboxylic acid ... Acyclic polyether dicarboxylic acids having butyl and tetradecyl side alkyl chains at the α-position of the carboxylic acid ... Acyclic polyether dicarboxylic acids having butyl and tetradecyl side alkyl chains at the α-position of the carboxylic acid ...
https://koreauniv.pure.elsevier.com/en/publications/studies-on-complexation-of-alkaline-earth-metal-cations-with-acyc
Acyclic Acids (Ethanoic Acids) < Carboxylic Acids << Organic Compounds (Organic Chemicals) <<< Compounds, Elements & more @...Acyclic Acids (Ethanoic Acids) < Carboxylic Acids << Organic Compounds (Organic Chemicals) <<< Compounds, Elements & more @...
... a 2 carbon straight-chain saturated carboxylic acid, that has an open-chain molecular structures as opposed to ring-shaped ... Acyclic Acids (Ethanoic Acids). "Acyclic Acids (Ethanoic Acids)" Acyclic Acid. In organic chemistry, Acyclic Acids (Ethanoic ... Uronic Acids *Glucuronates *Glucuronic Acid *Glucuronides *Hexuronic Acids *Iduronic Acid *Tricarboxylic Acids *Aconitic Acid * ... Ascorbic Acid *2,3-Diketogulonic Acid *Glucaric Acid *Gluconic Acids (Gluconates) *Glyceric Acids *Muramic Acids *Neuraminic ...
http://wellnessadvocate.com/?uid=84521
An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases|...An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases|...
Nucleic Acids Research ; Volume 27. p. 1271-1274. 1999. Martinez, Carlos I.; Thoresen, Lars; Burgess, Kevin; Gibbs, Richard A. ... An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases. ... An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases ... An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases ...
https://nofima.no/en/pub/1688525/
Scientific Outputs at a glance | Page 708 | Autorité européenne deScientific Outputs at a glance | Page 708 | Autorité européenne de
No abstract available Keywords: Food Contact Materials, Plastics, Monomers, Additives, Acrylic acid, 2-ethylhexyl ester, REF. ... No abstract available Keywords: Straight-chain; branched-chain; acetals; saturated; acyclic; primary alcohols; aldehydes; ... No abstract available Keywords: Straight-chain, branched-chain, unsaturated, primary alcohols, aldehydes, carboxylic acids, ... orthoester; formic acid; flavourings; safety. doi: 10.2903/j.efsa.2004.107 Question Number: EFSA-Q-2003-146a Panels: Panel on ...
http://www.efsa.europa.eu/fr/publications?page=707&%3Bamp%3Bf%5B0%5D=sm_field_so_type%3Ajournal_editorial&%3Bamp%3Bf%5B1%5D=sm_field_so_type%3Astatement_of_efsa&%3Bamp%3Bf%5B2%5D=im_field_subject%3A61906
EFSA Journal | Page 149 | Autorité européenne de sécurité des alimentsEFSA Journal | Page 149 | Autorité européenne de sécurité des aliments
No abstract available Keywords: Hydrocyanic acid, Prussic acid, Cyanide, Amygdalin, Linamarin, Prunasin, Flavourings doi: ... No abstract available Keywords: Straight-chain; branched-chain; acetals; saturated; acyclic; primary alcohols; aldehydes; ... No abstract available Keywords: Sucrose esters of fatty acids, sucroglycerides, E 473, E 474, food additive, emulsifier, ... No abstract available Keywords: para-Hydroxybenzoic acid alkyl esters, parabens, food additive, preservative doi: 10.2903/j. ...
http://www.efsa.europa.eu/fr/publications?page=148&f%5B0%5D=im_field_subject%3A63406&f%5B1%5D=im_field_subject%3A61861&f%5B2%5D=im_field_subject%3A70330&f%5B3%5D=im_field_subject%3A70319&%3Bf%5B1%5D=sm_field_so_type%3Aconclusion_on_pesticides&%3Bamp%3Bf%5B1%5D=im_field_subject%3A61906
Hydrocarbons, Acyclic - DrugBankHydrocarbons, Acyclic - DrugBank
Taurocholic Acid. Monocarboxylate transporter 1. transporter. DB04348. Taurocholic Acid. Sodium/bile acid cotransporter. ... Taurocholic Acid. Ileal sodium/bile acid cotransporter. transporter. DB04348. Taurocholic Acid. Canalicular multispecific ... Taurocholic Acid. ATP-binding cassette sub-family C member 11. transporter. DB04348. Taurocholic Acid. Solute carrier organic ... Taurocholic Acid. ATP-binding cassette sub-family G member 2. transporter. DB04348. Taurocholic Acid. Solute carrier organic ...
https://www.drugbank.ca/categories/DBCAT000365
Acyclic or Carbocyclic CompoundsAcyclic or Carbocyclic Compounds
SUBSTITUTED NAPHTHYLACETIC ACIDS. The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable ... NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS. The present invention relates to compounds of general formula I, (I) wherein ... The invention relates to an ester having at least one sulphonic group on the acid chain, a method for the production thereof ... The invention further relates a process of using dilute sulfuric acid and re-circulating the dilute sul... ...
http://www.sumobrain.com/ICL-C07C317-p6.html
Lewis acid catalysis - WikipediaLewis acid catalysis - Wikipedia
Only under Lewis acid catalysis do these reactions occur under synthetically useful conditions. Acyclic transition states are ... a Lewis acid assists in the generation of an acylium ion from an acid chloride (or occasionally acid anhydride). Although the ... In Lewis acid catalysis of organic reactions, a metal-based Lewis acid acts as an electron pair acceptor to increase the ... Lewis acid Chiral Lewis acid Catalysis Enantioselective synthesis Carey, Fransis A.; Sundberg, Richard J. (2007). Advanced ...
https://en.wikipedia.org/wiki/Lewis_acid_catalysis
Federal Register :: Foreign-Trade Zone 102-St. Louis, Missouri: Application For Foreign-Trade Subzone Status,...Federal Register :: Foreign-Trade Zone 102-St. Louis, Missouri: Application For Foreign-Trade Subzone Status,...
... saturated acyclic monocarboxylic acids and derivatives; unsaturated acyclic or cyclic monocarboxylic acids and derivatives; ... industrial monocarbolxylic fatty acids, acid oils from refining, and industrial fatty alcohols; prepared binders for foundry ... salts of oxometallic or peroxometallic acids; other salts of inorganic acids or peroxoacids; radioactive chemical elements and ... acyclic alcohols and derivatives; phenols and phenol-alcohols, and their derivatives; ethers, ether-alcohols, ether-phenols, ...
https://www.federalregister.gov/documents/2003/05/06/03-11176/foreign-trade-zone-102-st-louis-missouri-application-for-foreign-trade-subzone-status-bayer
Stereocontrolled transformation of cyclohexene β-amino esters into syn- or anti-difunctionalized acyclic β<sup>2,3</sup>-amino...Stereocontrolled transformation of cyclohexene β-amino esters into syn- or anti-difunctionalized acyclic β<sup>2,3</sup>-amino...
A stereocontrolled approach to functionalized acyclic β2,3- amino acid derivatives was accomplished from cis- or trans-2- ... N2 - A stereocontrolled approach to functionalized acyclic β2,3- amino acid derivatives was accomplished from cis- or trans-2- ... AB - A stereocontrolled approach to functionalized acyclic β2,3- amino acid derivatives was accomplished from cis- or trans-2- ... Stereocontrolled transformation of cyclohexene β-amino esters into syn- or anti-difunctionalized acyclic β2,3-amino acid ...
https://hungary.pure.elsevier.com/hu/publications/stereocontrolled-transformation-of-cyclohexene-%CE%B2-amino-esters-int
CompoundsEstersAlcoholsDerivativesSaltsNucleic acidSynthesisRetinoidCarbonylSialic AcidsCarboxylic acidCyclic or acyclicAllylicMoietyAmino Acid SeqInhibitorsAcetic acidEthersOxidationHydroxyNeuraminic AcidsFatty acidThereofReactionsDicarboxylicNitrogenMetabolismMeSHNucleosidesStructuresPathwayBoric AcidPeptides
Compounds17
  • In organic chemistry , Acyclic Acids (Ethanoic Acids) , as organic compounds are 2 carbon straight-chain saturated carboxylic acids , that have an open-chain molecular structures as opposed to ring-shaped structures. (wellnessadvocate.com)
  • Early developments in Lewis acid reagents focused on easily available compounds such as TiCl4, BF3, SnCl4, and AlCl3. (wikipedia.org)
  • Esters of Phosphorous Acid, Alkyl Phosphites and Related Compounds f. (elsevier.com)
  • Esters of Phosphoric Acid, Alkyl Phosphates and Related Compounds g. (elsevier.com)
  • Esters of Sulphurous Acid and Related Compounds h. (elsevier.com)
  • Esters of Sulphuric Acid and Related Compounds i. (elsevier.com)
  • In these compounds, the 5′-hydroxyl of the sugar moiety, or its equivalent in acyclic nucleosides (ganciclovir, penciclovir, acyclovir) which do not contain a complete sugar moiety, is replaced with a phosphorus-carbon bond. (google.com)
  • This compound belongs to the class of organic compounds known as tricarboxylic acids and derivatives. (drugbank.ca)
  • We characterized the inhibitory activity of several acetylenic and olefinic compounds on cytochrome P450 (CYP)-derived arachidonic acid ω-hydroxylation and epoxidation using rat renal cortical microsomes and recombinant CYP proteins. (aspetjournals.org)
  • Among the acetylenic compounds, 6-(2-propargyloxyphenyl)hexanoic acid (PPOH) and N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide were found to be potent and selective inhibitors of microsomal epoxidation with IC 50 values of 9 and 13 μM, respectively. (aspetjournals.org)
  • The olefinic compounds N-methylsulfonyl-12,12-dibromododec-11-enamide (DDMS) and 12,12-dibromododec-11-enoic acid (DBDD) exhibited a high degree of selectivity inhibiting microsomal ω-hydroxylation with an IC 50 value of 2 μM, whereas the IC 50 values for epoxidation were 60 and 51 μM for DDMS and DBDD, respectively. (aspetjournals.org)
  • Retinoids consist of a family of naturally occuring compounds including all-trans retinoic acid (ATRA), retinal, retinol (vitamin A), 9-cis retinoic acid, 13-cis retinoic acid as well as a large number of synthetic derivatives. (biomedsearch.com)
  • Isocrotonic acid, also known as perisocrotonate or (Z)-2-butenoic acid, belongs to the class of organic compounds known as straight chain fatty acids. (hmdb.ca)
  • belongs to the class of organic compounds known as straight chain fatty acids. (hmdb.ca)
  • These are compounds containing a saccharide unit which bears a carboxylic acid group. (hmdb.ca)
  • R)-5-Diphosphomevalonic acid, also known as mevalonate 5-diphosphate or mevalonic acid 5-pyrophosphate, belongs to the class of organic compounds known as organic pyrophosphates. (hmdb.ca)
  • These are organic compounds containing the pyrophosphate oxoanion, with the structure OP([O-])(=O)OP(O)([O-])=O (R)-5-Diphosphomevalonic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral (R)-5-Diphosphomevalonic acid exists in all living species, ranging from bacteria to humans. (hmdb.ca)
Esters16
  • 909. Esters/aliphatic acyclic prim. (inchem.org)
  • EVALUATION 1.1 Introduction The Committee evaluated a group of 32 flavouring agents that includes selected esters of aliphatic acyclic primary alcohols with branched-chain aliphatic acyclic acids using the Procedure for the Safety Evaluation of Flavouring Agents (the "Procedure") (see Figure 1 and Table 1). (inchem.org)
  • 1.2 Estimated daily per capita intake The total annual production volume of the 32 esters of aliphatic acyclic primary alcohols with branched-chain aliphatic acyclic acids from their use as flavouring substances is approximately 16 tonnes in the USA (NAS, 1987) and 32 tonnes in Europe (IOFI, 1995). (inchem.org)
  • The daily per capita intake of the branched-chain acids (i.e. isobutyric acid, isovaleric acid, and 2-methylbutyric acid) formed via hydrolysis of these esters is 2 mg/person per day in the USA and 3.1 mg/person per day in Europe. (inchem.org)
  • Esters of aliphatic acyclic primary alcohols and branched-chain aliphatic acyclic acids have been detected in a wide variety of foods. (inchem.org)
  • 1.3 Absorption, metabolism and elimination It is expected that the esters in this group will be readily hydrolysed to their component alcohols and carboxylic acids in the intestinal tract, blood and liver. (inchem.org)
  • Summary of results of the safety evaluations of esters of terpenoid alcohols and aliphatic carboxylic acids Step 1: All of the substances in the group are in structural class I, the human intake threshold of which is 1800 g per day. (inchem.org)
  • Data relevant to the Procedure for the Safety Evaluation of 26 esters formed from the esterification of the terpenoid alcohols, (for geraniol, nerol, ( )-citronellol and rhodinol) and saturated aliphatic carboxylic acids (linear saturated aliphatic acids (C 1 -C 6 ), isobutyric acid isovaleric acid and 2-ethylbutyric acid) are summarized. (inchem.org)
  • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on Sucrose esters of fatty acids E 473 and sucroglycerides E 474. (europa.eu)
  • 4. Esters of Mineral or Inorganic Acids a. (elsevier.com)
  • Esters of Boric Acid, Trialkyl Orthoborates b. (elsevier.com)
  • Esters of Silicic Acid, Tetra-Alkoxysilanes c. (elsevier.com)
  • Esters of Nitrous Acid, Alkyl Nitrites d. (elsevier.com)
  • Esters of Nitric Acid e. (elsevier.com)
  • 3 indent ) Nitrogen in acid moiety other than as nitroso or isocyanate (e.g., amino acid esters, etc. (uspto.gov)
  • One study investigating the short-term toxicity of Hexanoic acid, 2-ethyl-, C16-18 alkyl esters (CAS No. 90411-68-0) to aquatic invertebrates is available. (europa.eu)
Alcohols5
  • Relevant background information 2.1 Explanation 2.2 Biological data 2.2.1 Absorption, distribution and excretion 2.2.2 Biotransformations 2.2.2.1 Branched-chain aliphatic acids 2.2.2.2 Aliphatic linear alcohols 2.2.3 Toxicological studies 2.2.3.1 Acute toxicity 2.2.3.2 Short-term toxicity studies 2.2.3.3 Long-term toxicity/carcinogenicity studies 2.2.3.4 Genotoxicity studies 2.2.3.5 Reproductive toxicity studies 3. (inchem.org)
  • 16A Alcohols: Versatile Reagents: Part A. Alcohols as acids, bases, nucleophiles and electrophiles. (wiley.com)
  • Peroxy acid epoxidation of acyclic allylic alcohols. (biomedsearch.com)
  • With regards to the blood-brain barrier chain-length dependant absorption potential exists with the lower aliphatic alcohols and acids more readily being taken up than aliphatic alcohols/acids of longer chain-length (Gelman and Gilbertson, 1975). (europa.eu)
  • Taking into account the efficient biotransformation of the alcohols and the physicochemical properties of the corresponding carboxylic acids the potential for elimination into breast milk is considered to be low. (europa.eu)
Derivatives6
  • This thesis deals with different applications of organocatalysis, where amino acid derivatives and small peptides are applied as catalysts. (diva-portal.org)
  • The obtained amino acids were further applied in the semisynthesis of paclitaxel and docetaxel derivatives. (diva-portal.org)
  • A stereocontrolled approach to functionalized acyclic β 2,3 - amino acid derivatives was accomplished from cis- or trans-2- aminocyclohexenecarboxylates derived from bicyclic β-lactam regioisomers. (elsevier.com)
  • This stereospecific and stereocontrolled procedure was applied to the synthesis of acylic β 2,3 -amino acid derivatives functionalized with ester, nitrile, keto, alkyl or arylalkyl groups. (elsevier.com)
  • These are derivatives of lineolic acid. (hmdb.ca)
  • In biological evaluation of dentigerumycin E ( 1 ) and its chemical derivatives [2- N ,16- N -deoxydenteigerumycin E ( 2 ) and dentigerumycin methyl ester ( 3 )], only dentigerumycin E exhibited antiproliferative and antimetastatic activities against human cancer cells, indicating that N -OH and carboxylic acid functional groups are essential for the biological activity. (frontiersin.org)
Salts1
  • The present invention relates to a process for the production of alkali metal salts of dialkyldithiocarbamic acids and to alkali metal salts of dialkyldithiocarbamic acids produced according to said process. (sumobrain.com)
Nucleic acid7
  • Acyclic ( L )-threoninol nucleic acid (aTNA) containing thymine, cytosine and adenine nucleobases were synthesized and shown to form surprisingly stable triplexes with complementary single stranded homopurine DNA or RNA targets. (rsc.org)
  • acyclic L -threoninol nucleic acid ( L - a TNA). (rsc.org)
  • L - a TNA formed a more stable duplex with DNA and RNA than either D - a TNA or serinol nucleic acid (SNA) as the rigidity of the L -form was more optimal for interaction with natural nucleic acids. (rsc.org)
  • RNA is a nucleic acid , a complex, high-molecular-weight macromolecule composed of nucleotide chains whose sequence of bases conveys genetic information . (newworldencyclopedia.org)
  • The present invention describes terminal phosphate blocked nucleoside polyphosphates that are stable at high temperature and their use in nucleic acid amplification and analysis. (google.es)
  • Current invention further describes charge modified terminal phosphate blocked nucleoside polyphosphates for improved incorporation and direct loading of nucleic acid sequencing reactions onto separating media. (google.es)
  • 1. In a method for nucleic acid analysis, which includes a high temperature polymerase reaction of a nucleic acid template, a primer, a nucleic acid polymerase, and at least one nucleoside polyphosphate, the improvement comprising conducting said polymerase reaction in the presence of at least one thermally stable terminally blocked nucleoside polyphosphates, wherein said nucleic acid analysis is chain terminator DNA sequencing. (google.es)
Synthesis5
  • The synthesis of novel nucleotide analogues on the basis of ethylphosphonic acid was described. (sigmaaldrich.com)
  • Synthesis of acyclic oligonucleotides as antiviral and antiinflammatory agents and inhibitors of phospholipase A2. (wikipedia.org)
  • Synthesis and Stereocontrolled Equatorially Selective Glycosylation Reactions of a Pseudaminic Acid Donor: Importance of the Side-Chain Conformation and Regioselective Reduction of Azide Protecting Groups. (harvard.edu)
  • Stereoselective Synthesis of 5-epi-a-Sialosides Related to the Pseudaminic Acid Glycosides. (harvard.edu)
  • The vitamin A derivative retinoic acid is produced postembryonically in discrete portions of the songbird brain, including some of the nuclei involved in song production and song learning, and its synthesis is required for the normal maturation of song behavior. (biomedsearch.com)
Retinoid3
  • Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. (nih.gov)
  • We developed an acyclic retinoid, polyprenoic acid, that inhibits hepatocarcinogenesis in the laboratory and induces differentiation and apoptosis in cell lines derived from human hepatoma. (nih.gov)
  • In this study, we evaluated the comedolytic effect of a novel retinoic acid receptor (RAR)-gamma specific retinoid, ER36009, in the rhino mouse. (biomedsearch.com)
Carbonyl5
  • In reactions with polar mechanisms, Lewis acid catalysis often involves binding of the catalyst to Lewis basic heteroatoms and withdrawing electron density, which in turn facilitates heterolytic bond cleavage (in the case of Friedel-Crafts reaction) or directly activates the substrate toward nucleophilic attack (in the case of carbonyl addition reactions). (wikipedia.org)
  • Among the types of reactions that can be catalyzed by Lewis acids, those with carbonyl-containing substrates have received the greatest amount of attention. (wikipedia.org)
  • The models have their roots in knowledge of the structures of Lewis acid-carbonyl complexes which, through decades of research in theoretical calculations, NMR spectroscopy, and X-ray crystallography, were fairly firmly established in the early 1990s: σ-Complexation: The complex in which the Lewis acid interacts with the carbonyl compound through a σ-bond with the oxygen lone pair is both thermodynamically favored and catalytically relevant. (wikipedia.org)
  • After the step involving the hydride is complete, the acetal is removed (by reacting it with an aqueous acid), giving back the original carbonyl. (wikipedia.org)
  • On the basis of SAR studies, acyclic allylic analogs of uracil bearing carbonyl and sulphonyl groups at N-3 position are expected to be probable lead molecules against HIV-RT. (biomedcentral.com)
Sialic Acids2
  • Reassessment of the Stereoselectivity of the 5-Azido-5-deacetamidosialyl Thioglycosides and Use of Triflate as Nucleophile in the Zbiral Deamination of Sialic Acids. (harvard.edu)
  • The role of sialic acids in the immune recognition of xenografts. (harvard.edu)
Carboxylic acid3
  • Acyclic polyether dicarboxylic acids having butyl and tetradecyl side alkyl chains at the α-position of the carboxylic acid sidearm unit were prepared by the reaction of bisphenol and 2-bromoalkanoic acid in the presence of sodium hydride with quantitative yields. (elsevier.com)
  • The structural analog of coronatine, the isoleucine conjugate of 1-oxo-indanoyl-4-carboxylic acid, effectively mimics the action of JA, but does not increase the level of endogenous JA. (plantphysiol.org)
  • The reaction mechanism involves the formation of a positively charged halonium ion in a molecule that also contains a carboxylic acid (or other functional group that is a precursor to it). (wikipedia.org)
Cyclic or acyclic2
  • L is H or a linker moiety selected from the group consisting of substituted or unsubstituted, linear or branched cyclic or acyclic alkyl, alkenyl, alkynyl, aromatic, or heterocyclic. (google.es)
  • These NRTIs may be cyclic or acyclic analogs of natural nucleosides. (biomedcentral.com)
Allylic1
  • Development of acyclic allylic nucleoside analogs, which act as NRTIs against HIV, involves both the computational and synthetic methods. (biomedcentral.com)
Moiety1
  • The hydrogen bond network around the acyclic sugar moiety indicates that DEA is more tightly connected to the protein than the cyclic sugar Ado analogues. (rcsb.org)
Amino Acid Seq1
  • The absolute configuration of dentigerumycin E was established based on the advanced Marfey's method, ROESY NMR correlations, and analysis of the amino acid sequence of the ketoreductase domain in the biosynthetic gene cluster. (frontiersin.org)
Inhibitors1
  • Unlike cyclic sugar Ado analogue inhibitors, including mechanism-based inhibitors, DEA is an acyclic sugar Ado analogue, and the C2' and C3' have opposite chirality to those of the cyclic sugar Ado inhibitors. (rcsb.org)
Acetic acid2
  • The slightly yellow solution is cooled in an ice bath and 60 mL of glacial acetic acid (ca. 1 mol) and 50 mL of water are added. (orgsyn.org)
  • The solution is cooled and the now deep red solution is neutralized with glacial acetic acid (ca. 4.5 mL) until the color turns yellow. (orgsyn.org)
Ethers1
  • Silyl ether (most popular ones include trimethylsilyl (TMS), tert -butyldimethylsilyl (TBDMS), tri- iso -propylsilyloxymethyl (TOM), and triisopropylsilyl (TIPS) ethers) - Removed by acid or fluoride ion. (wikipedia.org)
Oxidation3
  • p -Methoxybenzyl ether (PMB) - Removed by acid, hydrogenolysis, or oxidation. (wikipedia.org)
  • i.e., one protein can catalyze the oxidation of arachidonic acid at multiple sites. (aspetjournals.org)
  • oxidation leads to hexoses and sugar acids. (thefreedictionary.com)
Hydroxy1
  • Finally, the last part describes development of a proline-catalyzed Mannich reation between N -acyl imines and protected α-hydroxyaldehyes, providing access to different α-hydroxy-β-amino acids in good yields and high enantioselctivity (92-99% ee). (diva-portal.org)
Neuraminic Acids2
  • This graph shows the total number of publications written about "Neuraminic Acids" by people in Harvard Catalyst Profiles by year, and whether "Neuraminic Acids" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Neuraminic Acids" by people in Profiles. (harvard.edu)
Fatty acid5
  • Linoleic acid is a doubly unsaturated fatty acid, also known as an omega-6 fatty acid, occurring widely in plant glycosides. (hmdb.ca)
  • In this particular polyunsaturated fatty acid (PUFA), the first double bond is located between the sixth and seventh carbon atom from the methyl end of the fatty acid (n-6). (hmdb.ca)
  • Linoleic acid is an essential fatty acid in human nutrition because it cannot be synthesized by humans. (hmdb.ca)
  • Lineolic acid is a polyunsaturated omega-6 18 carbon long fatty acid, with two CC double bonds at the 9- and 12-positions. (hmdb.ca)
  • The free fatty acid for different oil was also determined immediately after extraction and also on storage for two weeks. (bartleby.com)
Thereof1
  • The invention relates to an ester having at least one sulphonic group on the acid chain, a method for the production thereof and the use of the ester as a plasticizer for polymers. (sumobrain.com)
Reactions11
  • The reactions of (Z)-N,S-dimethylthiobenzimidate N-oxide, with methylmagnesium bromide and aqueous acid and base were investigated. (illinois.edu)
  • The ability of a primary amine containing acyclic beta(3)-amino acids to catalyze direct asymmetric anti-selective Mannich-type reactions is presented. (diva-portal.org)
  • In Lewis acid catalysis of organic reactions, a metal-based Lewis acid acts as an electron pair acceptor to increase the reactivity of a substrate. (wikipedia.org)
  • Many classical reactions involving carbon-carbon or carbon-heteroatom bond formation can be catalyzed by Lewis acids. (wikipedia.org)
  • In addition to accelerating the reactions, Lewis acid catalysts are able to impose regioselectivity and stereoselectivity in many cases. (wikipedia.org)
  • Over the years, versatile catalysts bearing ligands designed for specific applications have facilitated improvement in both reactivity and selectivity of Lewis acid-catalyzed reactions. (wikipedia.org)
  • The dichotomy can have important consequences in some reactions, as in the case of Lewis acid-promoted acetal substitution reactions, where the SN1 and SN2 mechanisms shown below may give different stereochemical outcomes. (wikipedia.org)
  • In Diels-Alder and 1,3-dipolar cycloaddition reactions, Lewis acids lower the LUMO energy of the dienophile or dipolarphile, respectively, making it more reactive toward the diene or the dipole. (wikipedia.org)
  • In addition to rate acceleration, Lewis acid-catalyzed reactions sometimes exhibit enhanced stereoselectivity, which stimulated the development of stereoinduction models. (wikipedia.org)
  • Only under Lewis acid catalysis do these reactions occur under synthetically useful conditions. (wikipedia.org)
  • Acyclic transition states are believed to be operating in both reactions for either 1,2- or 1,4- addition, and steric factors control stereoselectivity. (wikipedia.org)
Dicarboxylic1
  • Mognonov, D. 2011-02-02 00:00:00 The mechanism of rearrangement of polycarboxyimidates prepared by the reaction of dinitriles with dicarboxylic acids at elevated temperature was studied. (deepdyve.com)
Nitrogen1
  • In protein science , an Imino Acid (Secondary Amino Acid) is a molecule, related to amino acids (differing in the bonding to the nitrogen), that contains both an imino (>C=NH) and a carboxyl (-C(=O)-OH) functional group, which occurs as either an acyclic acid or a cyclic imino acid . (wellnessadvocate.com)
Metabolism5
  • The acid is as an intermediate in the metabolism of the amino acid isoleucine (Voet & Voet, 1990) 0207 n-Butyl 2-methylbutyrate No N/R No safety concern USA: 0.02 Europe: 26 0208 Hexyl 2-methylbutanoate No N/R No safety concern USA: 8.6 Europe: 4.9 Table 1. (inchem.org)
  • Both the hydrolysis data and the metabolism of aliphatic carboxylic acids are discussed in the introduction to this chapter on flavouring agents. (inchem.org)
  • Is the Subject Area "Amino acid metabolism" applicable to this article? (plos.org)
  • Linoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism. (hmdb.ca)
  • Hydroxyisocaproic acid is an end product of leucine metabolism in human tissues such as muscle and connective tissue. (hmdb.ca)
MeSH2
  • Sugar Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • Pentetic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Nucleosides1
  • Nucleosides Nucleotides & Nucleic Acids, 29 (9), 707−720. (etis.ee)
Structures4
  • Structures of complexes of macrocycle 7 and its acyclic control 8 are similar except for differences in relative orientations of corresponding atoms in the linking moieties of 7 and 8. (rcsb.org)
  • Structures of the different Samples and Solvents Sample 1: Vegetable Oil (Oleic acid) Oleic acid has the chemical formula C17H33COOH Due to its large nonpolar portion, oleic acid is insoluble in water and, being less dense than water, it floats on the water surface. (bartleby.com)
  • Zuschriften DOI: 10.1002/ange.201103422 G-Quadruplexes An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies** Florian Hamon, Eric Largy, Aurore Gudin-Beaurepaire, Myriam Rouchon-Dagois, Assitan Sidibe, David Monchaud, Jean-Louis Mergny, Jean-Francois Riou, Chi-Hung Nguyen, and Marie-Paule Teulade-Fichou* Quadruplex nucleic acids are secondary structures that may form in sequences containing guanine repeats. (docme.ru)
  • Searching for Bayesian network structures in the space of restricted acyclic partially directed graphs. (springer.com)
Pathway5
  • The CYP monooxygenases constitute a major metabolic pathway for arachidonic acid in the rat kidney. (aspetjournals.org)
  • The signal transduction initiating volatile biosynthesis may involve the activation of the octadecanoid pathway, as exemplified by the transient increase of endogenous jasmonic acid (JA) in leaves of lima bean ( Phaseolus lunatus ) after treatment with the macromolecular elicitor cellulysin. (plantphysiol.org)
  • Early intermediates of the pathway, especially 12-oxo-phytodienoic acid (PDA), are able to induce the biosynthesis of the diterpenoid-derived 4,8,12-trimethyltrideca-1,3,7,11-tetraene. (plantphysiol.org)
  • In humans, (R)-5-diphosphomevalonic acid is involved in the metabolic disorder called the cholesteryl ester storage disease pathway. (hmdb.ca)
  • 5-Diphosphomevalonic acid (CAS: 1492-08-6) is a metabolic intermediate in the mevalonate pathway, catalyzed by the enzyme phosphomevalonate kinase from 5-phosphomevalonate (Wikipedia). (hmdb.ca)
Boric Acid1
  • 2. A low detonation velocity explosive consisting essentially of a particulate mixture of ortho-boric acid and alpha trinitrotoluene, said mixture containing about 60 percent by weight of ortho-boric acid, said boric acid comprised of about 77 percent spherical particles having a mean particle diameter of about 275 microns and about 23 percent of spherical particles having a particle diameter less than about 44 microns. (freepatentsonline.com)
Peptides1
  • A single drawing solution that both chemists and biologists can trust to accurately handle and represent organic, organometallic and polymeric and biopolymer materials (including amino acids, peptides and DNA and RNA sequences) and to deal with advanced forms of stereochemistry. (cambridgesoft.com)
Synthesis of bridged tricyclo[5.2.1.01,5]decanes via nickel-catalyzed asymmetric domino cyclization of enynones | Nature...
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Quaternary-centre-guided synthesis of complex polycyclic terpenes | Nature
Quaternary-centre-guided synthesis of complex polycyclic terpenes | Nature (nature.com)
RCSB PDB - 1K0U: Inhibition of S-adenosylhomocysteine Hydrolase by 'acyclic sugar' Adenosine Analogue D-eritadenine
RCSB PDB - 1K0U: Inhibition of S-adenosylhomocysteine Hydrolase by 'acyclic sugar' Adenosine Analogue D-eritadenine (rcsb.org)
The Effect of Acyclic Retinoid on the Metabolomic Profiles of Hepatocytes and Hepatocellular Carcinoma Cells
The Effect of Acyclic Retinoid on the Metabolomic Profiles of Hepatocytes and Hepatocellular Carcinoma Cells (journals.plos.org)
Hydrocarbons, Acyclic - DrugBank
Hydrocarbons, Acyclic - DrugBank (drugbank.ca)
Acyclic polyimides based on dinitriles and dicarboxylic acids, Russian Journal of Applied Chemistry | 10.1134/S1070427210120256...
Acyclic polyimides based on dinitriles and dicarboxylic acids, Russian Journal of Applied Chemistry | 10.1134/S1070427210120256... (deepdyve.com)
Organic Chemistry: A Guided Inquiry | Organic Chemistry | Chemistry | Subjects | Wiley
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RNA - New World Encyclopedia
RNA - New World Encyclopedia (newworldencyclopedia.org)
Chew and spit: tree-feeding notodontid caterpillars anoint girdles with saliva | SpringerLink
Chew and spit: tree-feeding notodontid caterpillars anoint girdles with saliva | SpringerLink (link.springer.com)
WHO - Detail article
WHO - Detail article (apps.who.int)
Glycol nucleic acid - Wikipedia
Glycol nucleic acid - Wikipedia (en.wikipedia.org)
Differential Induction of Plant Volatile Biosynthesis in the Lima Bean by Early and Late Intermediates of the Octadecanoid...
Differential Induction of Plant Volatile Biosynthesis in the Lima Bean by Early and Late Intermediates of the Octadecanoid... (plantphysiol.org)
Pantothenic acid - DrugBank
Pantothenic acid - DrugBank (drugbank.ca)
Glycinamid - DrugBank
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India exports of organic chemicals to South Korea - 1988-2019 Data | 2020 Forecast
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Taurine | Harvard Catalyst Profiles | Harvard Catalyst
Taurine | Harvard Catalyst Profiles | Harvard Catalyst (connects.catalyst.harvard.edu)
Acyclic diene metathesis (ADMET) polymerization
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US20030171229A1 - Concentrated aqueous betaine-type surfactant compositions and process for their preparation - Google...
US20030171229A1 - Concentrated aqueous betaine-type surfactant compositions and process for their preparation - Google... (patents.google.com)
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US8389577B2 - Method of treating a human being for a class of metabolic defects and energy production disorders -... (patents.google.com)
Hexanoic acid, 2-ethyl-, C16-18-alkyl esters - Registration Dossier - ECHA
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Human Metabolome Database: Showing metabocard for Hydroxyisocaproic acid (HMDB0000746)
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