Organophosphonates: Carbon-containing phosphonic acid compounds. Included under this heading are compounds that have carbon bound to either OXYGEN atom or the PHOSPHOROUS atom of the (P=O)O2 structure.Phosphorous Acids: Inorganic derivatives of phosphorus trihydroxide (P(OH)3) and its tautomeric form dihydroxyphosphine oxide (HP=O(OH)2). Note that organic derivatives of phosphonic acids are listed under are ORGANOPHOSPHONATES.Fosfomycin: An antibiotic produced by Streptomyces fradiae.Organophosphorus Compounds: Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.Aminoethylphosphonic Acid: An organophosphorus compound isolated from human and animal tissues.Abstracting and Indexing as Topic: Activities performed to identify concepts and aspects of published information and research reports.Nucleotides: The monomeric units from which DNA or RNA polymers are constructed. They consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group. (From King & Stansfield, A Dictionary of Genetics, 4th ed)Holmium: Holmium. An element of the rare earth family of metals. It has the atomic symbol Ho, atomic number 67, and atomic weight 164.93.Data Mining: Use of sophisticated analysis tools to sort through, organize, examine, and combine large sets of information.Sulfur Compounds: Inorganic or organic compounds that contain sulfur as an integral part of the molecule.Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)Peptide Nucleic Acids: DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.Nucleic Acid Hybridization: Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)Nucleic Acid Denaturation: Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.RNA: A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)L Forms: Bacterial variants, unable to form a complete cell wall, which are formed in cultures by various bacteria; granules (L bodies) appear, unite, and grow into amorphous bodies which multiply and give rise to bacterial cells morphologically indistinguishable from the parent strain.Nucleic Acid Conformation: The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.Oligonucleotides: Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.MalonatesPatents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Halogens: A family of nonmetallic, generally electronegative, elements that form group 17 (formerly group VIIa) of the periodic table.Inventions: A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.AcetalsButanesMolecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Halogenation: Covalent attachment of HALOGENS to other compounds.Bromine: A halogen with the atomic symbol Br, atomic number 36, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested.Methylene Chloride: A chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations. Its primary use is as a solvent in manufacturing and food technology.Distillation: A chemical process for separating the components of a liquid mixture by boiling and collecting condensed vapors.Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.Sodium Bicarbonate: A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.Toluene: A widely used industrial solvent.Carbamates: Derivatives of carbamic acid, H2NC(=O)OH. Included under this heading are N-substituted and O-substituted carbamic acids. In general carbamate esters are referred to as urethanes, and polymers that include repeating units of carbamate are referred to as POLYURETHANES. Note however that polyurethanes are derived from the polymerization of ISOCYANATES and the singular term URETHANE refers to the ethyl ester of carbamic acid.Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.Hydrocarbons, Chlorinated: Hydrocarbon compounds with one or more of the hydrogens replaced by CHLORINE.Thymine Nucleotides: Phosphate esters of THYMIDINE in N-glycosidic linkage with ribose or deoxyribose, as occurs in nucleic acids. (From Dorland, 28th ed, p1154)Deoxyribonucleotides: A purine or pyrimidine base bonded to a DEOXYRIBOSE containing a bond to a phosphate group.Kinetics: The rate dynamics in chemical or physical systems.Substrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.Thymidine Kinase: An enzyme that catalyzes the conversion of ATP and thymidine to ADP and thymidine 5'-phosphate. Deoxyuridine can also act as an acceptor and dGTP as a donor. (From Enzyme Nomenclature, 1992) EC 2.7.1.21.Adenosine Triphosphate: An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.Nucleosides: Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed)ThymidineDatabases, Pharmaceutical: Databases devoted to knowledge about PHARMACEUTICAL PRODUCTS.Pharmacological Processes: The metabolism of drugs and their mechanisms of action.Trichloroacetic Acid: A strong acid used as a protein precipitant in clinical chemistry and also as a caustic for removing warts.Tretinoin: An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).Hyperostosis, Cortical, Congenital: A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)Vitamin A: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.Affinity Labels: Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.Lipid Metabolism: Physiological processes in biosynthesis (anabolism) and degradation (catabolism) of LIPIDS.Leydig Cells: Steroid-producing cells in the interstitial tissue of the TESTIS. They are under the regulation of PITUITARY HORMONES; LUTEINIZING HORMONE; or interstitial cell-stimulating hormone. TESTOSTERONE is the major androgen (ANDROGENS) produced.Leydig Cell Tumor: Gonadal interstitial or stromal cell neoplasm composed of only LEYDIG CELLS. These tumors may produce one or more of the steroid hormones such as ANDROGENS; ESTROGENS; and CORTICOSTEROIDS. Clinical symptoms include testicular swelling, GYNECOMASTIA, sexual precocity in children, or virilization (VIRILISM) in females.Receptors, Retinoic Acid: Proteins in the nucleus or cytoplasm that specifically bind RETINOIC ACID or RETINOL and trigger changes in the behavior of cells. Retinoic acid receptors, like steroid receptors, are ligand-activated transcription regulators. Several types have been recognized.Myxomatosis, InfectiousSiphonaptera: An order of parasitic, blood-sucking, wingless INSECTS with the common name of fleas.Pulmonary Stretch Receptors: Stretch receptors found in the bronchi and bronchioles. Pulmonary stretch receptors are sensors for a reflex which stops inspiration. In humans, the reflex is protective and is probably not activated during normal respiration.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Publications: Copies of a work or document distributed to the public by sale, rental, lease, or lending. (From ALA Glossary of Library and Information Science, 1983, p181)Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Myxoma virus: The type species of LEPORIPOXVIRUS causing infectious myxomatosis, a severe generalized disease, in rabbits. Tumors are not always present.Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
(1/16) 3,4-Dihydrocoumarin hydrolase with haloperoxidase activity from Acinetobacter calcoaceticus F46.

A novel lactonohydrolase, an enzyme that catalyzes the hydrolysis of 3,4-dihydrocoumarin, was purified 375-fold to apparent homogeneity, with a 22.7% overall recovery, from Acinetobacter calcoaceticus F46, which was isolated as a fluorene-assimilating micro-organism. The molecular mass of the native enzyme, as estimated by high-performance gel-permeation chromatography, is 56 kDa, and the subunit molecular mass is 30 kDa. The enzyme specifically hydrolyzes 3,4-dihydrocoumarin, and the Km and Vmax for 3,4-dihydrocoumarin are 0.806 mM and 4760 U.mg-1, respectively. The N-terminal and internal amino acid sequences of the enzyme show high similarity to those of bacterial non-heme haloperoxidases. The enzyme exhibits brominating activity with monochlorodimedon in the presence of H2O2 and 3, 4-dihydrocoumarin or an organic acid, such as acetate and n-butyrate.  (+info)

(2/16) Al-induced efflux of organic acid anions is poorly associated with internal organic acid metabolism in triticale roots.

The secretion of organic acid anions from roots has been identified as a mechanism of resistance to Al. However, the process leading to the secretion of organic acid anions is poorly understood. The effect of Al on organic acid metabolism was investigated in two lines of triticale (xTriticosecale Wittmark) differing in Al-induced secretion of malate and citrate and in Al resistance. The site of Al-induced secretion of citrate and malate from a resistant line was localized to the root apices (terminal 5 mm). The levels of citrate (root apices and mature root segments) and malate (mature segments only) in roots increased during exposure to Al, but similar changes were observed in both triticale genotypes. The in vitro activities of four enzymes involved in malate and citrate metabolism (citrate synthase, phosphoenolpyruvate carboxylase, malate dehydrogenase, and NADP-isocitrate dehydrogenase) were similar for sensitive and resistant lines in both root apices and mature root segments. The response of these enzymes to pH did not differ between tolerant and sensitive lines or in the presence and absence of Al. Moreover, cytoplasmic and vacuolar pH were not affected by exposure to Al in either line. Together, these results indicate that the Al-dependent efflux of organic acid anions from the roots of triticale is not regulated by their internal levels in the roots or by the capacity of the root cells to synthesize malate and citrate.  (+info)

(3/16) Propionyl-coenzyme A synthetases of Ralstonia solanacearum and Salmonella choleraesuis display atypical kinetics.

Propionyl-coenzyme A synthetases (PrpE) of Salmonella choleraesuis and Ralstonia solanacearum sharing 62% identity in amino acid sequence to each other were cloned, expressed in Escherichia coli and purified. Both enzymes catalyzed acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A formation with the highest k(cat)/K(m) values for propionate. They displayed sigmoidal homotrophic autoactivation kinetics for propionate but not for the other acyl substrates tested. Besides, substrate inhibition kinetics was observed for co-substrates, i.e. ATP and CoA. Based on the kinetic data reported herein, the reaction mechanisms of the enzyme are discussed.  (+info)

(4/16) The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.

In previous work, we showed that the binding of the liver x receptor alpha:peroxisome proliferator-activated receptor alpha (LXRalpha:PPARalpha) heterodimer to the murine Cyp7a1 gene promoter antagonizes the stimulatory effect of their respective ligands. In this study, we determined if LXRalpha:PPARalpha can also regulate human CYP7A1 gene promoter activity. Co-expression of LXRalpha and PPARalpha in McArdle RH7777 hepatoma cells decreased the activity of the human CYP7A1 gene promoter in response to fibrates and 25-hydroxycholesterol. In vitro, the human CYP7A1 Site I bound LXRalpha:PPARalpha, although with substantially less affinity compared with the murine Cyp7a1 Site I. The binding of LXRalpha:PPARalpha to human CYP7A1 Site I was increased in the presence of either LXRalpha or PPARalpha ligands. In HepG2 hepatoblastoma cells, fibrates and 25-hydroxycholesterol inhibited the expression of the endogenous CYP7A1 gene as well as the human CYP7A1 gene promoter when co-transfected with plasmids encoding LXRalpha and PPARalpha. However, a derivative of the human CYP7A1 gene promoter that contains a mutant form of Site I that does not bind LXRalpha:PPARalpha was not inhibited by WY 14,643 or 25-hydroxycholesterol in both McArdle RH7777 and HepG2 cells. The ligand-dependent recruitment of LXRalpha:PPARalpha heterodimer onto the human CYP7A1 Site I can explain the inhibition of the human CYP7A1 gene promoter in response to fibrates and 25-hydroxycholesterol.  (+info)

(5/16) Corn hybrid affects in vitro and in vivo measures of nutrient digestibility in dogs.

Corn is a commonly used ingredient in dry pet foods because there is a stable supply and it is a relatively inexpensive source of nutrients. Corn hybrids are available that are higher in CP and amylose and lower in phytate concentration than conventional hybrids. Approximately 500 mg of high-protein (HP), high-protein, low-phytate (HPLP), and high-amylose (HA) corn were compared with conventional (CONV) corn and amylomaize starch (AM) in triplicate and exposed to pepsin/hydrochloric acid and pancreatin to simulate hydrolytic digestion. Substrate remaining after this was used to determine in vitro colonic fermentation. Organic matter disappearances as a result of hydrolytic digestion were >80% for CONV, HP, and HPLP, whereas HA (60.7%) and AM (43.7%) were lower (P < 0.05). Total digestion (TD) values after hydrolytic digestion and 8 h of fermentation using canine fecal inoculum were greater (P < 0.05) for CONV, HP, and HPLP vs. HA and AM. The residue left after hydrolytic digestion of all substrates was poorly fermented. Five ileal-cannulated dogs were fed each corn hybrid at approximately 31% of the diet in a 5 x5 Latin square design. Dogs fed diets containing HP corn had higher (P < 0.05) ileal OM digestibility (70.3%) and tended (P < 0.10) to have higher DM digestibility (64.6%). Ileal starch digestibilities were lower (P < 0.05) for dogs fed HA (64.0%) and AM (63.0%). Ileal digestibilities of essential (71.2%), nonessential (67.4%), and total (69.0%) AA tended to be higher (P < 0.10) for HP diets compared with CONV (66.4, 62.4, and 64.0%, respectively). Total-tract DM, OM, CP, and GE digestibilities (77, 82, 77, and 84%, on average, respectively) were higher (P < 0.05) for dogs fed CONV, HP, and HPLP than for those fed AM (66.9, 71.6, 72.6, and 76.5%) and HA (60.6, 65.7, 69.7, and 71.5%). Total-tract fat digestibilities were lower (P < 0.05) for dogs fed HA diets (86.6%) than for all other treatments (91.0%, on average). Total-tract starch digestibilities were higher (P < 0.05) for dogs fed CONV, HP, and HPLP (98%, on average) compared with HA (72.8%) and AM (76.5%). No differences were detected among treatments in fecal bifidobacteria, lactobacilli, or Clostridium perfringens concentrations. The experiments demonstrated that HP and HPLP corn had hydrolytic digestion and fermentation characteristics similar to those of CONV corn, whereas HA resulted in similar responses to AM, a well-established resistant starch ingredient.  (+info)

(6/16) Enantioselective fluorescent recognition of chiral acids by cyclohexane-1,2-diamine-based bisbinaphthyl molecules.

The cyclohexane-1,2-diamine-based bisbinaphthyl macrocycles (S)-/(R)-5 and their cyclic and acyclic analogues are synthesized. The interactions of these compounds with various chiral acids are studied. Compounds (S)-/(R)-5 exhibit highly enantioselective fluorescent responses and high fluorescent sensitivity toward alpha-hydroxycarboxylic acids and N-protected amino acids. Among these interactions, (S)-mandelic acid (10(-3) M) led to over 20-fold fluorescence enhancement of (S)-5 (1.0 x 10(-5) M in benzene/0.05% DME) at the monomer emission, and (S)-hexahydromandelic acid (10(-3) M) led to over 80-fold fluorescence enhancement. These results demonstrate that (S)-5 is useful as an enantioselective fluorescent sensor for the recognition of the chiral acids. On the basis of the study of the structures of (S)-5 and the previously reported 1,2-diphenylethylenediamine-based bisbinaphthyl macrocycle (S)-4, the large fluorescence enhancement of (S)-5 with a chirality-matched alpha-hydroxycarboxylic acid is attributed to the formation of a structurally rigidified host-guest complex and the further interaction of this complex with the acid to suppress the photoinduced electron-transfer fluorescent quenching caused by the nitrogens in (S)-5.  (+info)

(7/16) Bioactive constituents from Chinese natural medicines. XXVIII. Chemical structures of acyclic alcohol glycosides from the roots of Rhodiola crenulata.

Five new glycosides, creosides I, II, III, IV, and V, were isolated from the methanolic extract of the roots of Rhodiola crenulata, together with 21 known compounds. The chemical structures of new constituents were elucidated on the basis of chemical and physicochemical evidence.  (+info)

(8/16) Mutation of the active site carboxy-lysine (K70) of OXA-1 beta-lactamase results in a deacylation-deficient enzyme.

 (+info)

*  Iodolactonization
Bartlett, P. A.; Myerson, J. (1978). "Stereoselective epoxidation of acyclic olefinic carboxylic acids via iodolactonization". ... The reaction mechanism involves the formation of a positively charged halonium ion in a molecule with a carboxylic acid or ... 6-heptadien-4-carboxylic acid derivatives". Tetrahedron Letters. 29 (13): 1517. doi:10.1016/S0040-4039(00)80340-8. Baldwin, ...
*  Enders SAMP/RAMP hydrazone-alkylation reaction
In 1976, Meyers reported the first alkylation reaction of metallated azaenolates of hydrazones with an acyclic amino acid-based ... With para-tosylate acid added, the hydrazone compounds can be transformed to the corresponding ketones with almost quantitative ... The combination of cyclic amino acid derivatives (SAMP and RAMP) and the powerful hydrazone techniques were pioneered by E. J. ... Both SAMP and RAMP are synthesized from amino acids. The detailed synthesis of these two auxiliaries are shown below. The ...
*  Thiosulfinate
... related thiosulfinates show radical-trapping antioxidant activity associated with easy formation of sulfenic acids The acyclic ... The thiosulfinate group can occur in cyclic as well as acyclic structures. A variety of acyclic and cyclic thiosulfinates are ... Methyl methanethiosulfinate decomposes thermally giving methanesulfenic acid (CH3SOH), the simplest sulfenic acid, as well as ... Asparagusic acid S-oxide and brugierol are other natural 1,2-dithiolane-1-oxides occurring in Asparagus o cinalis and Brugiera ...
*  Endiandric acid C
The Nicolaou group therefore sought to synthesize endiandric acid C from an acyclic symmetric diacetylenic diol precursor, 14 ( ... Endiandric acid C, isolated from the Endiandra introrsa tree, is a well characterized chemical compound. Endiadric acid C is ... Endiandric acid C is also isolated from E. xanthocarpa species. Endiandric acids are also found in Beilschmiedia trees, which ... This compound has the best antibacterial activity of Endiandrianic acid A-G compounds. Endiandric acid C was tested towards ...
*  Okadaic acid
Like the others, this synthesis divided okadaic acid into three components along the acyclic segments. However, designed to ... A polyketide, polyether derivative of a C38 fatty acid, okadaic acid and other members of its family have shined light upon ... However, the unique function of okadaic acid upon cells maintained biological interest in the molecule. Okadaic acid has been ... As above, spiroketalization was performed thermodynamically with introduction of acid. Ley's synthesis of okadaic acid is most ...
*  Lewis acid catalysis
Only under Lewis acid catalysis do these reactions occur under synthetically useful conditions. Acyclic transition states are ... a Lewis acid assists in the generation of an acylium ion from an acid chloride (or occasionally acid anhydride). Although the ... In Lewis acid catalysis of organic reactions, a metal-based Lewis acid acts as an electron pair acceptor to increase the ... Lewis acid Chiral Lewis acid Catalysis Enantioselective synthesis Carey, Fransis A.; Sundberg, Richard J. (2007). Advanced ...
*  Pederin
Here, pederic acid is added to the protected compound in LiHMDS and THF, producing a 75% yield. The protecting groups are then ... introducing stereoselective reduction of the acyclic ketone. Michael addition of nitromethane is performed. After several steps ... Beginning with (+)-benzoylselenopederic acid, Zn(BH4)2 reduction is applied, ... 2. Stereocontrolled synthesis of (+)-benzoylselenopederic acid and total synthesis of (+)-pederin". Tetrahedron Letters. 26 (52 ...
*  Gadopentetic acid
Gd-DTPA is classed as an acyclic, ionic gadolinium contrast medium. Its paramagnetic property reduces the T1 relaxation time ( ... Gadobenic acid Gadoxetic acid Murphy KJ, Brunberg JA, Cohan RH (1996). "Adverse reactions to gadolinium contrast media: a ... Gadopentetic acid is one of the trade names for a gadolinium-based MRI contrast agent, usually administered as a salt of a ...
*  Protecting group
Removed by acid. Normally, the cleavage of acyclic acetals is easier than of cyclic acetals. Acylals - Removed by Lewis acids. ... Protection of carboxylic acids: Methyl esters - Removed by acid or base. Benzyl esters - Removed by hydrogenolysis. tert-Butyl ... Methylthiomethyl ether - Removed by acid. Pivaloyl (Piv) - Removed by acid, base or reductant agents. It is substantially more ... Silyl esters - Removed by acid, base and organometallic reagents. Orthoesters - Removed by mild aqueous acid to form ester, ...
*  Bombus lucorum
MAP type secretions that contain fatty acid derivatives and mevalonic acid derivatives in the form of acyclic diterpenes. It ... The two types are PP type secretions that contain only fatty acid derivatives and PP + ... ethyl esters of fatty acids. Other components include ethyl dodecanoate (6%), ethyl tetradecanoate (2%), ethyl (Z)-hexadec-9- ...
*  Formic acid
ISBN 3-527-30673-0. Balabin, Roman M (2009). "Polar (Acyclic) Isomer of Formic Acid Dimer: Gas-Phase Raman Spectroscopy Study ... Formic acid, systemically named methanoic acid, is the simplest carboxylic acid. The chemical formula is HCOOH or HCO2H. It is ... ChemSub Online (Formic acid). Formic Acid Use in Beekeeping: Handbook and Manual of Treatments. Formic Acid Use by ants: ... Yields of up to 53% formic acid can be achieved. In the laboratory, formic acid can be obtained by heating oxalic acid in ...
*  Glycol nucleic acid
Synthesis of acyclic oligonucleotides as antiviral and antiinflammatory agents and inhibitors of phospholipase A2. PCT Int. ... Oligonucleotide synthesis Abiogenesis Threose nucleic acid Peptide nucleic acid Locked nucleic acid Zhang Lilu; Peritz Adam; ... Glycol nucleic acid (GNA) is a polymer similar to DNA or RNA but differing in the composition of its "backbone". GNA is not ... It is possibly the simplest of the nucleic acids, so making it a hypothetical precursor to RNA. ...
*  Flippin-Lodge angle
L.A. Flippin & C.H. Heathcock (1983) Acyclic stereoselection. 16. High diastereofacial selectivity in Lewis acid mediated ... amino acid side chains in enzyme active sites; see below). Planar electrophiles include aldehydes and ketones, carboxylic acid- ... These nucleophiles can be paired with an array of planar electrophiles: aldehydes and ketones, carboxylic acid-derivatives, and ... Mahrwald, Rainer (1999). "Diastereoselection in Lewis-Acid-Mediated Aldol Additions" (PDF). Chem. Rev. 99: 1095-1120, esp. pp. ...
*  Amino acid
... acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid residues form the second-largest ... "N-alkylated alpha-amino acid". The α-carboxylic acid group of amino acids is a weak acid, meaning that it releases a hydron ( ... The other product of transamidation is a keto acid that enters the citric acid cycle. Glucogenic amino acids can also be ... Only 837 D-amino acids were found in Swiss-Prot database (187 million amino acids analysed). The 20 amino acids that are ...
*  Acyclic diene metathesis
... chiral polymers and polymers with embedded amino acids. The high functional group tolerance of ruthenium-catalyzed ADMET has ... Acyclic diene metathesis or 'ADMET' (distinguish from ADME) is a special type of olefin metathesis used to polymerize terminal ... Mutlu, H.; Montero de Espinosa, L.; Meier, M.A.R. (2011). "Acyclic diene metathesis: a versatile tool for the construction of ... Wagener, K.B.; Boncella, J.M.; Nel, J.G. (1991). "Acyclic diene metathesis (ADMET) polymerization". Macromolecules. 24 (10): ...
*  SAMPL Challenge
... an acyclic CB7 derivative and two host from the octa-acid family. Participants were also encouraged to submit predictions for ... The SAMPL6 testing systems include cucurbit[8]uril, octa-acid, tetra-endo-methyl octa-acid, and a series of fragment-like small ... Host molecules included cucurbit[7]uril (CB7) and octa-acid. The SAMPL4 hydration challenge involved 49 submissions from 19 ...
*  Mucobromic acid
8 HBr Mucobromic acid exists as a mixture acyclic and cyclic isomers. The compound can be reduced using sodium borohydride to ... Mucobromic acid is an organic compound that consists of a dibrominated alkene with aldehyde and carboxylic acid functional ... This compound, and the analogous mucochloric acid (CAS #87-56-9), form the group of known mucohalic acids. The bromide appears ... Wasserman, H. H.; Precopio, F. M. (1952). "Studies on the mucohalic acids .1. The structure of mucoxychloric acid". J. Am. Chem ...
*  Imine Diels-Alder reaction
4) In many cases, cyclic dienes give higher diastereoselectivities than acyclic dienes. Use of amino-acid-based chiral ... Cyclic, acyclic, and tethered imines have all been employed in the reaction with success. (1) Simple alkyl or aryl amines are ... The lowest-energy transition state for the concerted process places the imine lone pair (or coordinated Lewis acid) in an exo ... 2) When the imine nitrogen is protonated or coordinated to a strong Lewis acid, the mechanism shifts to a stepwise, Mannich- ...
*  Aziridine
... is less basic than acyclic aliphatic amines, with a pKa of 7.9 for the conjugate acid, due to increased s character ... N-unsubstituted aziridines can be opened with olefins in the presence of strong Lewis acid B(C 6F 5) 3. The toxicology of a ... CH 2-CH+ 2-R This reaction type requires a Lewis acid catalyst such as boron trifluoride. In this way 2-phenyl-N-tosylaziridine ...
*  Petasis reaction
... diallylamine and a dimethylketal-protected boronic acid 1 is coupled to form the acyclic, stereochemically-defined amino- ... In α-amino acid synthesis, α-keto acids, such as glyoxylic and pyruvic acid, are stirred in ethanol, toluene, or ... Synthesis of amino acids β,γ-unsaturated, N-substituted amino acids are conveniently prepared through the condensation of ... When certain chiral amines, such as (S)-2-phenylglycinol, are mixed with an α-keto acid and vinyl boronic acid at room ...
*  Persistent carbene
The first acyclic persistent carbene was reported in 1996, thus showing that a cyclic backbone was not necessary for their ... NHCs are often strongly basic (the pKa value of the conjugate acid of an imidazol-2-ylidene was measured at ca. 24) and react ... These acyclic carbenes have diagnostic 13C NMR chemical shift values between 250-300 ppm for the carbenic carbon, further ... Unlike the cyclic derivatives, the acyclic carbenes are flexible with respect to rotation of the bonds to the carbenic atom. By ...
*  Saegusa-Ito oxidation
For acyclic substrates the reaction yields the thermodynamic E-olefin product exclusively. This discovery was preceded nearly ... yields the palladium hydride enone complex which upon reductive elimination yields the product along with acetic acid and Pd0. ... The reversibility of the elimination step allows equilibration, leading to the thermodynamic E-selectivity in acyclic ... Qiang Tu's synthesis of the Alzheimer's disease medication galantamine likewise used this reaction in the presence of an acid- ...
*  Apache Hive
Only in the recent version of Hive 0.14 were these functions fully added to support complete ACID properties. This is because ... Internally, a compiler translates HiveQL statements into a directed acyclic graph of MapReduce, Tez, or Spark jobs, which are ... ISBN 978-1-4493-8973-4. Hive Language Manual ACID and Transactions in Hive Hive A Warehousing Solution Over a MapReduce ... Support for insert, update, and delete with full ACID functionality was made available with release 0.14. ...
*  Sulfonamide
The related sulfinamides (R(S=O)NHR) are amides of sulfinic acids (R(S=O)OH) (see sulfinyl). Chiral sulfinamides such as tert- ... Hydrochlorothiazide is a drug that features both acyclic and cyclic sulfonamide groups. Camphorsultam is a sultam used as a ... Sulfonamide (medicine) Sulfamic acid Sulfamide Actor, P.; Chow, A. W.; Dutko, F. J.; McKinlay, M. A. (2005), "Chemotherapeutics ... Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group with an amine group. In ...
*  Allylic stannane addition
Lewis acid promoted and transmetalation reactions are much milder and have achieved synthetic utility. Intramolecular addition ... and depends on the relative energies of a number of acyclic transition states. (E)-Stannanes exhibit higher syn selectivity ... Chelation control using Lewis acids such as magnesium bromide can lead to high stereoselectivities for reactions of α-alkoxy ... Reagent control implies that a catalyst or Lewis acid promoter is serving as the stereocontrolling species. When all substrates ...
*  Benzhydryl compounds
... fluspirilene Acyclic (3°C): diphenhydramine (c.f deramciclane), orphenadrine, p-methyldiphenhydramine Acyclic (4°C): moxastine ... amfonelic acid Nitrogen: promethazine, imipramine, acepromazine, chlorpromazine, fluphenazine, mesoridazine, levomepromazine, ... cyproheptadine Acyclic: gilutensin Acyclic: (3-phenylpropylamine), tolpropamine, tolterodine Piperidine: desoxypipradrol, ... Acyclic: pridinol Pyrolidino: diphenylprolinol 2-Piperidine: pipradrol 4-Piperidine: terfenadine, fexofenadine Benzilic ester: ...
Atripla (Efavirenz, Emtricitabine, and Tenofovir Disoproxil Fumarate): Side Effects, Interactions, Warning, Dosage & Uses  Atripla (Efavirenz, Emtricitabine, and Tenofovir Disoproxil Fumarate): Side Effects, Interactions, Warning, Dosage & Uses
Too much lactic acid in your blood (lactic acidosis). Too much lactic acid is a serious but rare medical emergency that can ... VIREAD is the brand name for tenofovir DF, which is converted in vivo to tenofovir, an acyclic nucleoside phosphonate ( ... This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can ... Genotypic analysis of these isolates identified the M184V/I and/or K65R amino acid substitutions in the viral RT. In addition, ...
more infohttps://www.rxlist.com/atripla-drug.htm
Highly stable triple helix formation by homopyrimidine (l)-acyclic threoninol nucleic acids with single stranded DNA and RNA -...  Highly stable triple helix formation by homopyrimidine (l)-acyclic threoninol nucleic acids with single stranded DNA and RNA -...
... threoninol nucleic acid (aTNA) containing thymine, cytosine and adenine nucleobases were synthesized and shown to form ... Highly stable triple helix formation by homopyrimidine (L)-acyclic threoninol nucleic acids with single stranded DNA and RNA ... Acyclic (L)-threoninol nucleic acid (aTNA) containing thymine, cytosine and adenine nucleobases were synthesized and shown to ... Highly stable triple helix formation by homopyrimidine (L)-acyclic threoninol nucleic acids with single stranded DNA and RNA V ...
more infohttp://pubs.rsc.org/en/Content/ArticleLanding/2015/OB/c4ob02328e
Acyclic nucleotide analogues based on phosphonic acids]. | Sigma-Aldrich  Acyclic nucleotide analogues based on phosphonic acids]. | Sigma-Aldrich
Acyclic nucleotide analogues based on phosphonic acids].. [E V Efimtseva, S N Mikhaĭlov, M V Fomicheva, S V Meshkov, M S ... The synthesis of novel nucleotide analogues on the basis of ethylphosphonic acid was described. A rigid structural element, an ...
more infohttps://www.sigmaaldrich.com/catalog/papers/9551196
Acyclic Acids (Ethanoic Acids)  < Carboxylic Acids  << Organic Compounds (Organic Chemicals)  <<< Compounds, Elements & more  @...  Acyclic Acids (Ethanoic Acids) < Carboxylic Acids << Organic Compounds (Organic Chemicals) <<< Compounds, Elements & more @...
... a 2 carbon straight-chain saturated carboxylic acid, that has an open-chain molecular structures as opposed to ring-shaped ... Acyclic Acids (Ethanoic Acids). "Acyclic Acids (Ethanoic Acids)" Acyclic Acid. In organic chemistry, Acyclic Acids (Ethanoic ... Uronic Acids *Glucuronates *Glucuronic Acid *Glucuronides *Hexuronic Acids *Iduronic Acid *Tricarboxylic Acids *Aconitic Acid * ... Ascorbic Acid *2,3-Diketogulonic Acid *Glucaric Acid *Gluconic Acids (Gluconates) *Glyceric Acids *Muramic Acids *Neuraminic ...
more infohttp://wellnessadvocate.com/?uid=84521
Acyclic l-threoninol nucleic acid (l-aTNA) with suitable structural rigidity cross-pairs with DNA and RNA - Chemical...  Acyclic l-threoninol nucleic acid (l-aTNA) with suitable structural rigidity cross-pairs with DNA and RNA - Chemical...
... acyclicl-threoninol nucleic acid (l-aTNA). l-aTNA formed a more stable duplex with DNA and RNA than either d-aTNA or serinol ... nucleic acid (SNA) as the rigidity of the l-form was more optimal for interaction with natural nucleic acids. ... We report the hybridization properties of a novel artificial nucleic acid: ... We report the hybridization properties of a novel artificial nucleic acid: acyclicL-threoninol nucleic acid (L-aTNA). L-aTNA ...
more infohttp://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/c4cc09244a
911. Esters/branched-chain terpenoid alc./aliphatic acyclic lin./B-C carb. acids (WHO Food Additives Series 40)  911. Esters/branched-chain terpenoid alc./aliphatic acyclic lin./B-C carb. acids (WHO Food Additives Series 40)
... carboxylic acids (linear saturated aliphatic acids (C1-C6), isobutyric acid isovaleric acid and 2-ethylbutyric acid) are ... linear saturated aliphatic acids (C1-C6), isobutyric acid, isovaleric acid and 2-ethylbutyric acid). The four terpenoid ... acid is discussed in the monographs on saturated aliphatic acyclic linear primary alcohols aldehydes and acids and on saturated ... fatty acid or amino acid pathways (Voet & Voet, 1990). In general, the component linear saturated carboxylic acids (C1 - C6) ...
more infohttp://inchem.org/documents/jecfa/jecmono/v040je15.htm
Acyclic polyimides based on dinitriles and dicarboxylic acids, Russian Journal of Applied Chemistry | 10.1134/S1070427210120256...  Acyclic polyimides based on dinitriles and dicarboxylic acids, Russian Journal of Applied Chemistry | 10.1134/S1070427210120256...
"Acyclic polyimides based on dinitriles and dicarboxylic acids, Russian Journal of Applied Chemistry" on DeepDyve, the largest ... Acyclic polyimides based on dinitriles and dicarboxylic acids. Acyclic polyimides based on dinitriles and dicarboxylic acids ... Acyclic polyimides based on dinitriles and dicarboxylic acids. Ochirov, B.; Burdukovskii, V.; Mognonov, D. ... lp/springer_journal/acyclic-polyimides-based-on-dinitriles-and-dicarboxylic-acids-253lslzegY ...
more infohttps://www.deepdyve.com/lp/springer_journal/acyclic-polyimides-based-on-dinitriles-and-dicarboxylic-acids-253lslzegY
RCSB PDB - 478 Ligand Summary Page  RCSB PDB - 478 Ligand Summary Page
3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER. 478 as a ... Acids, Acyclic. *Amides. *Anti-Bacterial Agents. *Anti-HIV Agents. *Anti-Infective Agents ... Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. , PMID:21059682 ... 3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER. ...
more infohttps://www.rcsb.org/ligand/478
RCSB PDB - CAN Ligand Summary Page  RCSB PDB - CAN Ligand Summary Page
... nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to ... Acids, Acyclic. *Amino Acids. *Amino Acids, Peptides, and Proteins. *Butyrates. *Carboxylic Acids ... Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. , PMID:21059682 ...
more infohttps://www.rcsb.org/ligand/CAN
1,3,5-BENZENETRICARBOXYLIC ACID - DrugBank  1,3,5-BENZENETRICARBOXYLIC ACID - DrugBank
Acids, Acyclic. UNII. OU36OO5MTN. CAS number. Not Available. Weight. Average: 210.1403 Monoisotopic: 210.016437924 Chemical ... Tricarboxylic acids and derivatives. Alternative Parents. Benzoic acids / Benzoyl derivatives / Carboxylic acids / Organooxygen ... Tricarboxylic acid or derivatives / Benzoic acid / Benzoic acid or derivatives / Benzoyl / Benzenoid / Monocyclic benzene ... Organic acids and derivatives. Class. Carboxylic acids and derivatives. Sub Class. Tricarboxylic acids and derivatives. Direct ...
more infohttps://www.drugbank.ca/drugs/DB08632
WO2018128479 COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASES, COMPRISING SUBERIC ACID OR PHARMACEUTICALLY ACCEPTABLE...  WO2018128479 COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASES, COMPRISING SUBERIC ACID OR PHARMACEUTICALLY ACCEPTABLE...
... the composition comprising a suberic acid or a pharmaceutically acceptable salt thereof as an active ingredient. ... KO) 본 발명은 수베르산(suberic acid) 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 근육 질환 예방 또는 치료용 또는 근 기능 개선용 조성물에 관한 것이다.. ... EN) COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASES, COMPRISING SUBERIC ACID OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF ... 1. (WO2018128479) COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASES, COMPRISING SUBERIC ACID OR PHARMACEUTICALLY ...
more infohttps://patentscope.wipo.int/search/en/detail.jsf?docId=WO2018128479
Pentetic Acid | Profiles RNS  Pentetic Acid | Profiles RNS
Acids, Acyclic [D02.241.081]. *Acetates [D02.241.081.018]. *Pentetic Acid [D02.241.081.018.639] ... "Pentetic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject ... An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as ... This graph shows the total number of publications written about "Pentetic Acid" by people in this website by year, and whether ...
more infohttps://profiles.umassmed.edu/display/119682
Thioglycolates | Profiles RNS  Thioglycolates | Profiles RNS
Carboxylic Acids [D02.241]. *Acids, Acyclic [D02.241.081]. *Acetates [D02.241.081.018]. *Thioglycolates [D02.241.081.018.900] ...
more infohttps://profiles.umassmed.edu/display/119267
Federal Register
       :: 
      Foreign-Trade Zone 102-St. Louis, Missouri: Application For Foreign-Trade Subzone Status,...  Federal Register :: Foreign-Trade Zone 102-St. Louis, Missouri: Application For Foreign-Trade Subzone Status,...
... saturated acyclic monocarboxylic acids and derivatives; unsaturated acyclic or cyclic monocarboxylic acids and derivatives; ... industrial monocarbolxylic fatty acids, acid oils from refining, and industrial fatty alcohols; prepared binders for foundry ... salts of oxometallic or peroxometallic acids; other salts of inorganic acids or peroxoacids; radioactive chemical elements and ... acyclic alcohols and derivatives; phenols and phenol-alcohols, and their derivatives; ethers, ether-alcohols, ether-phenols, ...
more infohttps://www.federalregister.gov/documents/2003/05/06/03-11176/foreign-trade-zone-102-st-louis-missouri-application-for-foreign-trade-subzone-status-bayer
Chew and spit: tree-feeding notodontid caterpillars anoint girdles with saliva | SpringerLink  Chew and spit: tree-feeding notodontid caterpillars anoint girdles with saliva | SpringerLink
Formic acid and acyclic ketones in the spray of a caterpillar. Ann Entomol Soc Am 65:765-766CrossRefGoogle Scholar ... Contact with forceps caused the larva to discharge its VEG repeatedly, each time expelling formic acid directly at the forceps ... Dussourd DE (2015) Theroa zethus caterpillars use acid secretion of anti-predator gland to deactivate plant defense. PLoS ONE ...
more infohttps://link.springer.com/article/10.1007/s11829-016-9416-1
WO2003090691A3 - Method and compositions for identifying anti-hiv therapeutic compounds 
        - Google Patents  WO2003090691A3 - Method and compositions for identifying anti-hiv therapeutic compounds - Google Patents
C07F9/4006-Esters of acyclic acids which can have further substituents on alkyl ... C07F9/38-Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) ... Boronic acid inhibitors of HIV protease CN107709288A (en) * 2016-02-03. 2018-02-16. 四川海思科制药有限公司. Phosphamide derivative, method ... Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine US5610294A (en) 1991-10-11. 1997-03-11. The Du Pont ...
more infohttps://patents.google.com/patent/WO2003090691A3/en
US2768193A - Organosilicon compounds containing phosphorus 
        - Google Patents  US2768193A - Organosilicon compounds containing phosphorus - Google Patents
C07F9/4012-Esters of acyclic acids which can have further substituents on alkyl substituted by B, Si, P or a metal ... C07F9/4006-Esters of acyclic acids which can have further substituents on alkyl ... C07F9/38-Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) ... Preparation of esters of phosphorus acids silylalkyliques US5405983A (en) * 1993-12-28. 1995-04-11. Mona Industries, Inc.. ...
more infohttps://patents.google.com/patent/US2768193A/en
Pure and Applied Chemistry  Pure and Applied Chemistry
Lewis acids in diastereoselective processes involving acyclic radicals. Guindon, Y. / Guérin, Brigitte / Rancourt, J. / Chabot ...
more infohttps://www.degruyter.com/view/j/pac.1996.68.issue-1/issue-files/pac.1996.68.issue-1.xml
  • Mognonov, D. 2011-02-02 00:00:00 The mechanism of rearrangement of polycarboxyimidates prepared by the reaction of dinitriles with dicarboxylic acids at elevated temperature was studied. (deepdyve.com)
  • Pentetic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This graph shows the total number of publications written about "Pentetic Acid" by people in this website by year, and whether "Pentetic Acid" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Pentetic Acid" by people in Profiles. (umassmed.edu)
  • Acyclic ( L )-threoninol nucleic acid (aTNA) containing thymine, cytosine and adenine nucleobases were synthesized and shown to form surprisingly stable triplexes with complementary single stranded homopurine DNA or RNA targets. (rsc.org)
  • acyclic L -threoninol nucleic acid ( L - a TNA). (rsc.org)
  • L - a TNA formed a more stable duplex with DNA and RNA than either D - a TNA or serinol nucleic acid (SNA) as the rigidity of the L -form was more optimal for interaction with natural nucleic acids. (rsc.org)
  • Retinoids consist of a family of naturally occuring compounds including all-trans retinoic acid (ATRA), retinal, retinol (vitamin A), 9-cis retinoic acid, 13-cis retinoic acid as well as a large number of synthetic derivatives. (biomedsearch.com)
  • The combination of cyclic amino acid derivatives (SAMP and RAMP) and the powerful hydrazone techniques were pioneered by E. J. Corey and D. Enders in 1976, and were independently developed by D. Enders later. (wikipedia.org)
  • Therefore, although four isomers are possible for the azaenolate, only the one (azaenolate A) with the stereochemistry of its C=C double bonds being E and that of its C-N bond being Z stereochemistry is dominant (EC=CZC-N) for both cyclic and acyclic ketones. (wikipedia.org)
  • I have discovered that when an organosilicon compound containing a haloalkyl radical attached to silicon is reacted with an ester of an acid of trivalent phosphorus, an organosilicon compound is formed which contains phosphorus attached to silicon through aliphatic carbon. (google.com)
  • A class of acids containing a ring structure in which at least one atom other than CARBON is incorporated. (bireme.br)
  • Immunolocalization of retinoic acid biosynthesis systems in selected sites in rat. (biomedsearch.com)
  • RB3LYP calculations, reported here, indicate that peroxy acid s-cis conformer is more stable than its s-trans counterpart, in agreement with experimental data. (biomedsearch.com)
  • and (b) further reacting said malonic acid derivative as intermediate for the manufacture of Sevoflurane CF 3 --CH(OCH 2 F)--CF 3 . (patentsencyclopedia.com)
  • The vitamin A derivative retinoic acid is produced postembryonically in discrete portions of the songbird brain, including some of the nuclei involved in song production and song learning, and its synthesis is required for the normal maturation of song behavior. (biomedsearch.com)
  • More particularly, this invention is concerned with the product of reaction between (1) an organosilicon compound containing a haloalkyl radical attached to silicon and (2) an ester of an acid of trivalent phosphorus. (google.com)
  • These natural products include (-)-C10-demethyl arteannuin B, the structural analog of antimalarial artemisinin, the polypropionate metabolite (-)-Denticulatin A and B isolated from Siphonaria denticulata, zaragozic acid A, a potent inhibitor of sterol synthesis, and epothilone A and B, which have been proven to be very effective anticancer drugs. (wikipedia.org)
  • The synthesis of novel nucleotide analogues on the basis of ethylphosphonic acid was described. (sigmaaldrich.com)