3,4-Dihydrocoumarin hydrolase with haloperoxidase activity from Acinetobacter calcoaceticus F46. (1/16)

A novel lactonohydrolase, an enzyme that catalyzes the hydrolysis of 3,4-dihydrocoumarin, was purified 375-fold to apparent homogeneity, with a 22.7% overall recovery, from Acinetobacter calcoaceticus F46, which was isolated as a fluorene-assimilating micro-organism. The molecular mass of the native enzyme, as estimated by high-performance gel-permeation chromatography, is 56 kDa, and the subunit molecular mass is 30 kDa. The enzyme specifically hydrolyzes 3,4-dihydrocoumarin, and the Km and Vmax for 3,4-dihydrocoumarin are 0.806 mM and 4760 U.mg-1, respectively. The N-terminal and internal amino acid sequences of the enzyme show high similarity to those of bacterial non-heme haloperoxidases. The enzyme exhibits brominating activity with monochlorodimedon in the presence of H2O2 and 3, 4-dihydrocoumarin or an organic acid, such as acetate and n-butyrate.  (+info)

Al-induced efflux of organic acid anions is poorly associated with internal organic acid metabolism in triticale roots. (2/16)

The secretion of organic acid anions from roots has been identified as a mechanism of resistance to Al. However, the process leading to the secretion of organic acid anions is poorly understood. The effect of Al on organic acid metabolism was investigated in two lines of triticale (xTriticosecale Wittmark) differing in Al-induced secretion of malate and citrate and in Al resistance. The site of Al-induced secretion of citrate and malate from a resistant line was localized to the root apices (terminal 5 mm). The levels of citrate (root apices and mature root segments) and malate (mature segments only) in roots increased during exposure to Al, but similar changes were observed in both triticale genotypes. The in vitro activities of four enzymes involved in malate and citrate metabolism (citrate synthase, phosphoenolpyruvate carboxylase, malate dehydrogenase, and NADP-isocitrate dehydrogenase) were similar for sensitive and resistant lines in both root apices and mature root segments. The response of these enzymes to pH did not differ between tolerant and sensitive lines or in the presence and absence of Al. Moreover, cytoplasmic and vacuolar pH were not affected by exposure to Al in either line. Together, these results indicate that the Al-dependent efflux of organic acid anions from the roots of triticale is not regulated by their internal levels in the roots or by the capacity of the root cells to synthesize malate and citrate.  (+info)

Propionyl-coenzyme A synthetases of Ralstonia solanacearum and Salmonella choleraesuis display atypical kinetics. (3/16)

Propionyl-coenzyme A synthetases (PrpE) of Salmonella choleraesuis and Ralstonia solanacearum sharing 62% identity in amino acid sequence to each other were cloned, expressed in Escherichia coli and purified. Both enzymes catalyzed acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A formation with the highest k(cat)/K(m) values for propionate. They displayed sigmoidal homotrophic autoactivation kinetics for propionate but not for the other acyl substrates tested. Besides, substrate inhibition kinetics was observed for co-substrates, i.e. ATP and CoA. Based on the kinetic data reported herein, the reaction mechanisms of the enzyme are discussed.  (+info)

The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer. (4/16)

In previous work, we showed that the binding of the liver x receptor alpha:peroxisome proliferator-activated receptor alpha (LXRalpha:PPARalpha) heterodimer to the murine Cyp7a1 gene promoter antagonizes the stimulatory effect of their respective ligands. In this study, we determined if LXRalpha:PPARalpha can also regulate human CYP7A1 gene promoter activity. Co-expression of LXRalpha and PPARalpha in McArdle RH7777 hepatoma cells decreased the activity of the human CYP7A1 gene promoter in response to fibrates and 25-hydroxycholesterol. In vitro, the human CYP7A1 Site I bound LXRalpha:PPARalpha, although with substantially less affinity compared with the murine Cyp7a1 Site I. The binding of LXRalpha:PPARalpha to human CYP7A1 Site I was increased in the presence of either LXRalpha or PPARalpha ligands. In HepG2 hepatoblastoma cells, fibrates and 25-hydroxycholesterol inhibited the expression of the endogenous CYP7A1 gene as well as the human CYP7A1 gene promoter when co-transfected with plasmids encoding LXRalpha and PPARalpha. However, a derivative of the human CYP7A1 gene promoter that contains a mutant form of Site I that does not bind LXRalpha:PPARalpha was not inhibited by WY 14,643 or 25-hydroxycholesterol in both McArdle RH7777 and HepG2 cells. The ligand-dependent recruitment of LXRalpha:PPARalpha heterodimer onto the human CYP7A1 Site I can explain the inhibition of the human CYP7A1 gene promoter in response to fibrates and 25-hydroxycholesterol.  (+info)

Corn hybrid affects in vitro and in vivo measures of nutrient digestibility in dogs. (5/16)

Corn is a commonly used ingredient in dry pet foods because there is a stable supply and it is a relatively inexpensive source of nutrients. Corn hybrids are available that are higher in CP and amylose and lower in phytate concentration than conventional hybrids. Approximately 500 mg of high-protein (HP), high-protein, low-phytate (HPLP), and high-amylose (HA) corn were compared with conventional (CONV) corn and amylomaize starch (AM) in triplicate and exposed to pepsin/hydrochloric acid and pancreatin to simulate hydrolytic digestion. Substrate remaining after this was used to determine in vitro colonic fermentation. Organic matter disappearances as a result of hydrolytic digestion were >80% for CONV, HP, and HPLP, whereas HA (60.7%) and AM (43.7%) were lower (P < 0.05). Total digestion (TD) values after hydrolytic digestion and 8 h of fermentation using canine fecal inoculum were greater (P < 0.05) for CONV, HP, and HPLP vs. HA and AM. The residue left after hydrolytic digestion of all substrates was poorly fermented. Five ileal-cannulated dogs were fed each corn hybrid at approximately 31% of the diet in a 5 x5 Latin square design. Dogs fed diets containing HP corn had higher (P < 0.05) ileal OM digestibility (70.3%) and tended (P < 0.10) to have higher DM digestibility (64.6%). Ileal starch digestibilities were lower (P < 0.05) for dogs fed HA (64.0%) and AM (63.0%). Ileal digestibilities of essential (71.2%), nonessential (67.4%), and total (69.0%) AA tended to be higher (P < 0.10) for HP diets compared with CONV (66.4, 62.4, and 64.0%, respectively). Total-tract DM, OM, CP, and GE digestibilities (77, 82, 77, and 84%, on average, respectively) were higher (P < 0.05) for dogs fed CONV, HP, and HPLP than for those fed AM (66.9, 71.6, 72.6, and 76.5%) and HA (60.6, 65.7, 69.7, and 71.5%). Total-tract fat digestibilities were lower (P < 0.05) for dogs fed HA diets (86.6%) than for all other treatments (91.0%, on average). Total-tract starch digestibilities were higher (P < 0.05) for dogs fed CONV, HP, and HPLP (98%, on average) compared with HA (72.8%) and AM (76.5%). No differences were detected among treatments in fecal bifidobacteria, lactobacilli, or Clostridium perfringens concentrations. The experiments demonstrated that HP and HPLP corn had hydrolytic digestion and fermentation characteristics similar to those of CONV corn, whereas HA resulted in similar responses to AM, a well-established resistant starch ingredient.  (+info)

Enantioselective fluorescent recognition of chiral acids by cyclohexane-1,2-diamine-based bisbinaphthyl molecules. (6/16)

The cyclohexane-1,2-diamine-based bisbinaphthyl macrocycles (S)-/(R)-5 and their cyclic and acyclic analogues are synthesized. The interactions of these compounds with various chiral acids are studied. Compounds (S)-/(R)-5 exhibit highly enantioselective fluorescent responses and high fluorescent sensitivity toward alpha-hydroxycarboxylic acids and N-protected amino acids. Among these interactions, (S)-mandelic acid (10(-3) M) led to over 20-fold fluorescence enhancement of (S)-5 (1.0 x 10(-5) M in benzene/0.05% DME) at the monomer emission, and (S)-hexahydromandelic acid (10(-3) M) led to over 80-fold fluorescence enhancement. These results demonstrate that (S)-5 is useful as an enantioselective fluorescent sensor for the recognition of the chiral acids. On the basis of the study of the structures of (S)-5 and the previously reported 1,2-diphenylethylenediamine-based bisbinaphthyl macrocycle (S)-4, the large fluorescence enhancement of (S)-5 with a chirality-matched alpha-hydroxycarboxylic acid is attributed to the formation of a structurally rigidified host-guest complex and the further interaction of this complex with the acid to suppress the photoinduced electron-transfer fluorescent quenching caused by the nitrogens in (S)-5.  (+info)

Bioactive constituents from Chinese natural medicines. XXVIII. Chemical structures of acyclic alcohol glycosides from the roots of Rhodiola crenulata. (7/16)

Five new glycosides, creosides I, II, III, IV, and V, were isolated from the methanolic extract of the roots of Rhodiola crenulata, together with 21 known compounds. The chemical structures of new constituents were elucidated on the basis of chemical and physicochemical evidence.  (+info)

Mutation of the active site carboxy-lysine (K70) of OXA-1 beta-lactamase results in a deacylation-deficient enzyme. (8/16)

 (+info)

Only under Lewis acid catalysis do these reactions occur under synthetically useful conditions. Acyclic transition states are ... a Lewis acid assists in the generation of an acylium ion from an acid chloride (or occasionally acid anhydride). Although the ... In Lewis acid catalysis of organic reactions, a metal-based Lewis acid acts as an electron pair acceptor to increase the ... Lewis acid Chiral Lewis acid Catalysis Enantioselective synthesis Carey, Fransis A.; Sundberg, Richard J. (2007). Advanced ...
Bartlett, P. A.; Myerson, J. (1978). "Stereoselective epoxidation of acyclic olefinic carboxylic acids via iodolactonization". ... 6-heptadien-4-carboxylic acid derivatives". Tetrahedron Letters. 29 (13): 1517. doi:10.1016/S0040-4039(00)80340-8. Baldwin, ... mechanism involves the formation of a positively charged halonium ion in a molecule that also contains a carboxylic acid (or ...
Acyclic perfluoroethers are analogues of diethylether, e.g. O(C2F5)2, such perfluoro(2-ethoxyethane)sulfonic acid (PFEESA). ... Nafion is a perfluorinated polyether with pendant sulfonic acid groups (RSO3H). At high temperatures or in a fire, ...
Gd-DTPA is classed as an acyclic, ionic gadolinium contrast medium. Its paramagnetic property reduces the T1 relaxation time ( ... Gadopentetic acid, sold under the brand name Magnevist, is a gadolinium-based MRI contrast agent. It is usually administered as ... "Gadopentetic acid". Drug Information Portal. U.S. National Library of Medicine. "Gadopentetate dimeglumine". Drug Information ... "List of nationally authorised medicinal products: Gadopentetic acid" (PDF). Europeans Medicines Agency. 14 January 2021. US ...
Removed by acid. Normally, the cleavage of acyclic acetals is easier than of cyclic acetals. Acylals - Removed by Lewis acids. ... Tert-butyl ethers (tBu) - Removed by acid. Tetrahydropyranyl (THP) - Removed by acid. Tetrahydrofuran (THF) - Removed by acid. ... Protection of carboxylic acids: Methyl esters - Removed by acid or base. Benzyl esters - Removed by hydrogenolysis. tert-Butyl ... Methylthiomethyl ether - Removed by acid. Pivaloyl (Piv) - Removed by acid, base or reductant agents. It is substantially more ...
"Enantioselective Redox-Relay Oxidative Heck Arylations of Acyclic Alkenyl Alcohols using Boronic Acids". Journal of the ... In the conjugate addition case, intermediate 34 can be intercepted with formic acid to form a palladium complex (35) that can ... however acyclic internal alkenes were poor substrates for the reaction in terms of yield and regioselectivity. Unique to this ... and formic acid additive. Under these conditions, the conjugate addition product is formed preferentially to the vinylic ...
... two amino acids in the human body. The name can be abbreviated to diacid. The general formula for acyclic dicarboxylic acid is ... Acids from the two-carbon oxalic acid to the ten-member sebacic acid may be remembered using the mnemonic 'Oh My Son, Go And ... Suberic acid was first produced by nitric acid oxidation of cork (Latin suber). This acid is also produced when castor oil is ... These fatty acids, named diabolic acids, have a chain length depending on the fatty acid used in the culture medium. The most ...
The related sulfinamides (R(S=O)NHR) are amides of sulfinic acids (R(S=O)OH) (see sulfinyl). Chiral sulfinamides such as tert- ... Hydrochlorothiazide is a drug that features both acyclic and cyclic sulfonamide groups. Camphorsultam is a sultam used as a ... Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group (−OH) with an amine group. In ... Sulfonamide (medicine) Sulfamic acid Sulfamide Actor, P.; Chow, A. W.; Dutko, F. J.; McKinlay, M. A. "Chemotherapeutics". ...
Like the others, this synthesis divided okadaic acid into three components along the acyclic segments. However, designed to ... A polyketide, polyether derivative of a C38 fatty acid, okadaic acid and other members of its family have shined light upon ... However, the unique function of okadaic acid upon cells maintained biological interest in the molecule. Okadaic acid has been ... As above, spiroketalization was performed thermodynamically with introduction of acid. Ley's synthesis of okadaic acid is most ...
ISBN 978-3-527-30673-2. Roman M. Balabin (2009). "Polar (Acyclic) Isomer of Formic Acid Dimer: Gas-Phase Raman Spectroscopy ... Formic acid forms a high-boiling azeotrope with water (107.3 °C; 77.5% formic acid). Liquid formic acid tends to supercool. ... Formic acid is unique among the carboxylic acids in its ability to participate in addition reactions with alkenes. Formic acids ... Formic acid (from Latin formica 'ant'), systematically named methanoic acid, is the simplest carboxylic acid, and has the ...
"Acyclic phosphonate nucleotides and human adenylate kinases: impact of a borano group on alpha-P position". Nucleosides ... Nucleotides Nucleic Acids. 27 (4): 319-31. doi:10.1080/15257770801941952. PMID 18404568. S2CID 23819055. Gloria-Bottini F, ...
Here, pederic acid is added to the protected compound in LiHMDS and THF, producing a 75% yield. The protecting groups are then ... introducing stereoselective reduction of the acyclic ketone. Michael addition of nitromethane is performed. After several steps ... Beginning with (+)-benzoylselenopederic acid, Zn(BH4)2 reduction is applied, ... 2. Stereocontrolled synthesis of (+)-benzoylselenopederic acid and total synthesis of (+)-pederin". Tetrahedron Letters. 26 (52 ...
L.A. Flippin & C.H. Heathcock (1983) Acyclic stereoselection. 16. High diastereofacial selectivity in Lewis acid mediated ... amino acid side chains in enzyme active sites; see below). Planar electrophiles include aldehydes and ketones, carboxylic acid- ... These nucleophiles can be paired with an array of planar electrophiles: aldehydes and ketones, carboxylic acid-derivatives, and ... Mahrwald, Rainer (1999). "Diastereoselection in Lewis-Acid-Mediated Aldol Additions" (PDF). Chem. Rev. 99 (5): 1095-1120, esp. ...
D-alpha-amino acid - L-alpha-amino acid sequence can induce beta hairpin. It suggested that acyclic secondary amino acids are ... In enzymology, a N-methyl-L-amino-acid oxidase is an oxidase of a subtype of secondary amino acids. Imino acid Imidic acid ... Secondary amino acids can be classified to cyclic acids, such as proline, and acyclic N-substituted amino acids. In nature, ... Proline is the only proteinogenic secondary amino acids. Other secondary amino acids are non-proteinogenic amino acids. In ...
... has been employed for the formation of structures like α-amino acids, α-hydroxy-β-amino acids, α-ketoamides ... The original Passerini reaction produces acyclic depsipeptides which are labile in physiological conditions. To increase ... The Passerini reaction is a chemical reaction involving an isocyanide, an aldehyde (or ketone), and a carboxylic acid to form a ... Apart from forming α-acyloxy amide products, the Passerini reaction can be used to form heterocycles, polymers, amino acids, ...
... acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid residues form the second-largest ... Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although over 500 amino acids ... As both the amine and carboxylic acid groups of amino acids can react to form amide bonds, one amino acid molecule can react ... The other product of transamidation is a keto acid that enters the citric acid cycle. Glucogenic amino acids can also be ...
6R)-(E)-2,6-Dimethyl-2-octen-1,8-dioic acid is an acyclic monoterpene previously undocumented in insects. However, the chemical ... Terpenoids Citronellal Citronellol Citronellic acid Isopulegol (6R)-(E)-2,6-Dimethyl-2-octen-1,8-dioic acid Both 2,4- ...
The Nicolaou group therefore sought to synthesize endiandric acid C from an acyclic symmetric diacetylenic diol precursor, 14 ( ... Endiandric acid C, isolated from the tree Endiandra introrsa, is a well characterized chemical compound. Endiadric acid C is ... Endiandric acid C is also isolated from the species E. xanthocarpa. Endiandric acids are also found in Beilschmiedia trees, ... This compound has the best antibacterial activity of Endiandrianic acid A-G compounds. Endiandric acid C was tested towards ...
Triflic acid is often used. N-heterocyclic phosphenium (NHP) have also been reported. Reaction of PI3 with the α-diimine yields ... Acyclic phosphenium compounds were synthesized by Fleming's thesis advisor Robert Parry in 1976. Several methods exist for the ... Harrison, James F.; Liedtke, Richard C.; Liebman, Joel F. (1979-11-01). "The multiplicity of substituted acyclic carbenes and ... 1972-10-01). "Synthesis of a cyclic fluorodialkylaminophosphine and its coordination with boron acids. Formation of a unique ...
... chiral polymers and polymers with embedded amino acids. The high functional group tolerance of ruthenium-catalyzed ADMET has ... Acyclic diene metathesis or 'ADMET' (distinguish from ADME) is a special type of olefin metathesis used to polymerize terminal ... Mutlu, H.; Montero de Espinosa, L.; Meier, M.A.R. (2011). "Acyclic diene metathesis: a versatile tool for the construction of ... Wagener, K.B.; Boncella, J.M.; Nel, J.G. (1991). "Acyclic diene metathesis (ADMET) polymerization". Macromolecules. 24 (10): ...
2) This is not the case in Lewis-acid-promoted reactions, in which either the (Z)- or (E)-stannane affords the syn product ... and depends on the relative energies of a number of acyclic transition states. (E)-Stannanes exhibit higher syn selectivity ... Lewis acid promoted and transmetalation reactions are much milder and have achieved synthetic utility. Intramolecular addition ... Chelation control using Lewis acids such as magnesium bromide can lead to high stereoselectivities for reactions of α-alkoxy ...
During the synthesis of acetalated dextran both acyclic and cyclic acetals are formed. The acyclic acetals degrade into an ... This allows it to be processed in the same manner as many polyesters, like poly(lactic-co-glycolic acid), through processes ... The ratio of cyclic to acyclic acetals varies with reaction time since acyclic acetals are kinetically favored and cyclic ... "Acid-Degradable and Bioerodible Modified Polyhydroxylated Materials". Google Patent. Kauffman, KJ; Do, C; Sharma, S; Gallovic, ...
For acyclic substrates the reaction yields the thermodynamic E-olefin product exclusively. This discovery was preceded nearly ... yields the palladium hydride enone complex which upon reductive elimination yields the product along with acetic acid and Pd0. ... The reversibility of the elimination step allows equilibration, leading to the thermodynamic E-selectivity in acyclic ... Qiang Tu's synthesis of the Alzheimer's disease medication galantamine likewise used this reaction in the presence of an acid- ...
"Correlation of Relative Rates of Chromyl Chloride Oxidation and Chromic Acid Oxidation of Acyclic Alkenes Versus Alkene IPs and ... Nelson, Donna J.; Li, R.; Brammer, C. "The Correlation of Relative Rates of PdCl2 Oxidation of Functionalized Acyclic Alkenes ... Nelson, Donna J.; Li, Ruibo; Brammer Christopher N. "Substituent Effects in Acid-Catalyzed Hydration of Alkenes, Measured Under ... "The Use of Relative Magnitudes of Steric Effects to Explore Reactions of Molecular Halogens with Representative Acyclic Alkenes ...
3) In many cases, cyclic dienes give higher diastereoselectivities than acyclic dienes. Use of amino-acid-based chiral ... The lowest-energy transition state for the concerted process places the imine lone pair (or coordinated Lewis acid) in an exo ... 2) When the imine nitrogen is protonated or coordinated to a strong Lewis acid, the mechanism shifts to a stepwise, Mannich- ... 9) Simple unactivated imines react with hydrocarbon dienes only with the help of a Lewis acid; however, both electron-rich and ...
... isopimaric acid, abietic acid, levopimaric acid, palustric acid, neoabietic acid and dehydroabietic acid. Bicyclic resin acids ... acyclic polyterpenoids). The mono- and sesquiterpenes of the softwood are responsible for the typical smell of pine forest. ... Resin acids are usually tricyclic terpenoids, examples of which are pimaric acid, sandaracopimaric acid, ... are also found, such as lambertianic acid, communic acid, mercusic acid and secodehydroabietic acid. Cycloartenol, betulin and ...
... related thiosulfinates show radical-trapping antioxidant activity associated with easy formation of sulfenic acids The acyclic ... The thiosulfinate group can occur in cyclic as well as acyclic structures. A variety of acyclic and cyclic thiosulfinates are ... Takata, T; Endo, T (1990). "Thiosulphinic acids and esters". The Chemistry of Sulphinic Acids, Esters and Their Derivatives, S ... Methyl methanethiosulfinate decomposes thermally giving methanesulfenic acid (CH3SOH), the simplest sulfenic acid, as well as ...
The recent version of Hive 0.14 had these functions fully added to support complete ACID properties. Hive 0.14 and later ... Internally, a compiler translates HiveQL statements into a directed acyclic graph of MapReduce, Tez, or Spark jobs, which are ... ISBN 978-1-4493-8973-4. Hive Language Manual ACID and Transactions in Hive "Hive A Warehousing Solution Over a MapReduce ... Support for insert, update, and delete with full ACID functionality was made available with release 0.14. ...
"Decarboxylation of an α-amino acid coordinated to cobalt (III): kinetic stabilisation and molecular structure of a Co-C-N three ... pendant-arm macrocyclic and acyclic ligands." Inorganic Chemistry 36, no. 24 (1997): 5470-5477. Brothers, Penelope J., and ... "Condensation reactions of cobalt amino acid complexes with formaldehyde: Preparation and crystal structures of cobalt complexes ...
4-nitroperbenzoic acid > mCPBA and performic acid > peracetic acid > hydrogen peroxide > tert-butyl hydroperoxide. The ... The migrating group in acyclic ketones, usually, is not 1° alkyl group. However, they may be persuaded to migrate in preference ... some of the more common oxidants include meta-chloroperbenzoic acid (mCPBA) and trifluoroperacetic acid (TFPAA). The general ... Benzeneseleninic acid derivatives as catalysts have been reported to give high selectivity with hydrogen peroxide as the ...
"Synthesis of acyclic oligonucleotides as antiviral and antiinflammatory agents and inhibitors of phospholipase A2.", published ... Glycol nucleic acid (GNA), sometimes also referred to as glycerol nucleic acid, is a nucleic acid similar to DNA or RNA but ... Abiogenesis Locked nucleic acid Oligonucleotide synthesis Peptide nucleic acid Threose nucleic acid Zhang L, Peritz A, Meggers ... Schlegel MK, Essen LO, Meggers E (July 2008). "Duplex structure of a minimal nucleic acid". Journal of the American Chemical ...
Dominican Republic exported Acids; saturated acyclic monocarboxylic acids; esters of acetic acid n.e.s. in item no. 2915.3 to ... Dominican Republic exports of Acids; saturated acyclic monocarboxylic acids; esters of acetic acid n.e.s. in item no. 2915.3 ... HS Code 291539: Acids; saturated acyclic monocarboxylic acids; esters of acetic acid n.e.s. in item no. 2915.3. Please note: ... Acids; saturated acyclic monocarboxylic acids; esters of acetic acid n.e.s. in item no. 2915.3. 2021. World. 70.59. 22,516. Kg ...
Acids; acyclic polycarboxylic acids; maleic anhydride. 2021. Germany. 74.39. 42,000. Kg. Japan. Export. 291714. Acids; acyclic ... Acids; acyclic polycarboxylic acids; maleic anhydride. 2021. Germany. 8.07. 2,500. Kg. India. Export. 291714. Acids; acyclic ... Acids; acyclic polycarboxylic acids; maleic anhydride. 2021. Germany. 16,381.65. 11,107,400. Kg. China. Export. 291714. Acids; ... Acids; acyclic polycarboxylic acids; maleic anhydride. 2021. Germany. 1,760.78. 1,064,850. Kg. Italy. Export. 291714. Acids; ...
Only under Lewis acid catalysis do these reactions occur under synthetically useful conditions. Acyclic transition states are ... a Lewis acid assists in the generation of an acylium ion from an acid chloride (or occasionally acid anhydride). Although the ... In Lewis acid catalysis of organic reactions, a metal-based Lewis acid acts as an electron pair acceptor to increase the ... Lewis acid Chiral Lewis acid Catalysis Enantioselective synthesis Carey, Fransis A.; Sundberg, Richard J. (2007). Advanced ...
2-{[2-(6-Oxo-1,6-Dihydro-9h-Purin-9-Yl)ethyl](2-Phosphonoethyl)amino}ethoxy)methyl]phosphonic Acid. ... 4RAQ: Aza-acyclic Nucleoside Phosphonates Containing A Second Phosphonate Group As Inhibitors Of The Human, Plasmodium ...
Acrylates are derivatives of acrylic acid (the structural formula CH2=CHCO2H), including its salts and esters ... Organic Acids and Organic Acid derivatives. ⌊Carboxylic Acids and derivatives class. ⌊Carboxylic Acids Derivatives. ⌊Acyclic ... "Urocanic Acid (Glyoxalinylacrylic Acid)" Urocanic Acid. Urocanic Acid is an imidazole compound. ... Acrylates are derivatives of acrylic acid (the structural formula CH2=CHCO2H), including its salts and esters.. Examples of ...
Isobutylacetic acid. *4-Methylvaleric acid. Categories. *Acids, Acyclic. *Fatty Acids. *Fatty Acids, Volatile ... 4-METHYL VALERIC ACID. Find entries where: 4MV. is present as a standalone ligand in 1 entries ... Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. , PMID:21059682 ...
Asymmetric rhodium-catalysed addition of arylboronic acids to acyclic unsaturated esters containing a basic γ-amino group. In: ... Asymmetric rhodium-catalysed addition of arylboronic acids to acyclic unsaturated esters containing a basic γ-amino group. ... Asymmetric rhodium-catalysed addition of arylboronic acids to acyclic unsaturated esters containing a basic γ-amino group. / ... Asymmetric rhodium-catalysed addition of arylboronic acids to acyclic unsaturated esters containing a basic γ-amino group. ...
... saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulfonated ... 圖形 - 安哥拉 - 進口 - 進化 / 出口 - 進化 - NCE: 饱和无环一元羧酸 - saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides ... 圖形 - 安哥拉 - 進口 - 進化 / 出口 - 進化 - NCE: 饱和无环一元羧酸 - saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides ... 圖形 - 安哥拉 - 進口 - 進化 / 出口 - 進化
Carboxylic Acids [D02.241]. *Acids, Acyclic [D02.241.081]. *Acrylates [D02.241.081.069]. *Polymethacrylic Acids [D02.241. ...
Categories: Acids, Acyclic Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 39 ...
Aliphatic acyclic compounds. External Descriptors. *long-chain fatty acid (CHEBI:15756 ). *straight-chain saturated fatty acid ... Palmitic acid is the first fatty acid produced during fatty acid synthesis and is the precursor to longer fatty acids. As a ... Palmitic acid. Description. Palmitic acid, or hexadecanoic acid, is one of the most common saturated fatty acids found in ... The word "napalm" is derived from the words naphthenic acid and palmitic acid (Wikipedia ). Palmitic acid is also used in the ...
Formic acid, acetic acid, oxalic acid, acrylic acid, etc., are cited as the organic carboxylic acid and acetic anhydride, etc ... are used as the organic carboxylic acid anhydride. The organic carboxylic acid, etc., are added in an amount of 0.01-5.0 pts.wt ... The acrylonitrile is preferably used in an amount of ≥4.0 mol based on 1 mol sulfuric acid. COPYRIGHT: (C)1992,JPO&Japio ... CONSTITUTION: Acrylonitrile is reacted with sulfuric acid at ≥95% concentration and isobutylene in the presence of an organic ...
... with hydroxypropyl functionality were synthesized and their properties in the presence of different nucleic acids were studied ... The ΔTm values were calculated by subtracting Tm of the free nucleic acid from Tm of the complex. Every ΔTm value reported here ... Piantanida, I.; Palm, B.S.; Čudić, P.; Žinić, M.; Schneider, H.J. Interactions of acyclic and cyclic bis-phenanthridinium ... Chalikian, T.V.; Völker, J.; Plum, G.E.; Breslauer, K.J. A more unified picture for the thermodynamics of nucleic acid duplex ...
Tariff No.: 2915.90.20 - Aromatic anhydrides, halides, peroxides and peroxyacids, of saturated acyclic monocarboxylic acids, ... which provides for Saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their ... The subject product, 4-Chlorophenyl chloroformate, is a halogenated aromatic ester of a formic acid derivative (halogenated) ...
... phosphonic acids. C07H15/203 - Monocyclic carbocyclic rings other than cyclohexane rings. C07H15/26 - Acyclic or carbocyclic ... C07K1/1077 - {by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids} ... C07H13/00 - Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e ... Modification of Cell Surfaces by Enzymatic Introduction of Special Sialic Acid Analogues journal, February 1993 * Kosa, R. E.; ...
Miscellaneous cyclic and acyclic chemicals and chemical products, excluding fatty acid esters Oct 2023 131.314 Index Dec 2007= ... Inorganic acids, inc hydrochloric, sulfuric acid and other Oct 2023 113.491 Index Dec 2008=100 111.920 Index Dec 2008=100 ... Sulfuric acid Oct 2023 185.752 Index Jun 1987=100 185.752 Index Jun 1987=100 297.574 Index Jun 1987=100 Index Jun 1987=100 ... Fatty acids Oct 2023 234.689 Index Dec 2007=100 236.332 Index Dec 2007=100 255.623 Index Dec 2007=100 Index Dec 2007=100 ...
Acids, Acyclic [D02.241.081]. *Butyrates [D02.241.081.114]. *Butyric Acid [D02.241.081.114.750] ... A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester. ... "Butyric Acid" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Alcohol and fatty acid stimulation of neurotensin release from rat small intestine. Endocrinology. 1985 Mar; 116(3):1133-8. ...
Acids, Acyclic [D02.241.081]. *Acetates [D02.241.081.018]. *Acetamides [D02.241.081.018.110]. *Iodoacetamide [D02.241.081.018. ...
FIGURE 34EXPORT VALUE OF ACIDS, RATED ACYCLIC MONOCARBOXYLIC ACIDS, AND ACETIC ACID, BY KEY COUNTRY, 2017-2021 (USD)113. TABLE ... FIGURE 34EXPORT VALUE OF ACIDS, RATED ACYCLIC MONOCARBOXYLIC ACIDS, AND ACETIC ACID, BY KEY COUNTRY, 2017-2021 (USD)113. TABLE ... TABLE 18IMPORT VALUE OF ACIDS, SATURATED ACYCLIC MONOCARBOXYLIC ACIDS, AND ACETIC ACID, BY KEY COUNTRY, 2021 (USD)115. FIGURE ... TABLE 18IMPORT VALUE OF ACIDS, SATURATED ACYCLIC MONOCARBOXYLIC ACIDS, AND ACETIC ACID, BY KEY COUNTRY, 2021 (USD)115. FIGURE ...
Alkane: An acyclic saturated hydrocarbon, with the general formula C n H 2n+2 . Also called paraffin . ... Carboxylic acid: an organic compound that contains a carboxyl group (C(=O)OH). The general formula of a carboxylic acid is R- ... Melting points of Hydrocarbons, Alcohols and Acids. Carbon number Melting point of hydrocarbons, alcohols and acids, C1-C16, ... Hydrocarbons, Linear Alcohols and Acids - Densities Density of hydrocarbons like alcohols and acids as function of carbon ...
The production method according to the present invention is characterized in that a D-amino acid oxidase used in step 2 in the ... The present invention relates to a granular catalyst for the hydrolysis of amino nitriles and/or amino amides to amino acids or ... The use of an arylvinyl α-carbonyl acid ester compound (I) as a photoinitiator in LED photopolymerization and a preparation ... USE OF ARYLVINYL A-CARBONYL ACID ESTER COMPOUND AS PHOTOINITIATOR IN LED PHOTOPOLYMERIZATION AND PREPARATION METHOD THEREFOR. ...
Acids and Bases.. * Stereochemistry- Optical activity; Chirality; Topicity and prostereoisomerism; Conformations of acyclic and ... Acids and Bases- Measures of acid-base strength; Hard and soft acids and bases. ... Carboxylic acid dimers, alcohol-amine, amides etc. Designing molecular squares and boxes, giant self-assembling capsules, ...
Triazole-linked locked nucleic acids. Pawan Kumar / University of Oxford. No. 9:. Synthesis and genetic selection of acyclic ... NEW NUCLEIC ACID BUILDING BLOCKS. Session chair: Nathan Luedtke. 9:20. Modified nucleic acids for crosslinking and catalysis. ... In the first session "new nucleic acid building blocks", Annemieke Madder reported on modified nucleic acids for crosslinks and ... NUCLEIC ACID ANALOGS AND LIPIDS. Session chair: Oliver Seitz. 14:00. Nucleolipids: Synthesis, biomedical activity, and ...
2-(N-MORPHOLINO)-ETHANESULFONIC ACID. Find entries where: MES. is present as a standalone ligand in 1,797 entries ... Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. , PMID:21059682 ...
1,2-diol / Alcohol / Aliphatic acyclic compound / Alpha-hydroxy acid / Beta-hydroxy acid / Carbonyl group / Carboxylic acid / ... Carboxylic acid derivative / Dicarboxylic acid or derivatives / Fatty acid / Hydrocarbon derivative / Hydroxy acid / ... Short-chain hydroxy acids and derivatives / Beta hydroxy acids and derivatives / Monosaccharides / Fatty acids and conjugates ... Sugar acid. show 7 more. Molecular Framework. Aliphatic acyclic compounds. External Descriptors. 2,3-dihydroxybutanedioic acid ...
Table 16 Amino Acid Substitutions in Viremic Subjects Across HBV Trials of VIREAD Compensated Liver Disease. Decompensated ... In vivo tenofovir disoproxil fumarate is converted to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analog of ... Build-up of an acid in your blood (lactic acidosis). Lactic acidosis can happen in some people who take VIREAD. Lactic acidosis ... VIREAD is the brand name for tenofovir disoproxil fumarate (a prodrug of tenofovir) which is a fumaric acid salt of bis- ...
I. Diagnostic Ions for Acyclic Compounds with up to One Functional Group. September 13, 2022 ... carboxylic acids, amines, halides, thiols, thiones, esters, thioesters, amides and more ... The review covers wide-ranging electron ionization (EI) dissociation reactions for various acyclic compounds and their ...
... a-Amino Acid Derivatives in Enatiopure Form via Stereoslective Addition of Grignard Reagents to a Chiral Acyclic Nitrone ... Synthesis and in-vitro evaluation of s-allyl cysteine ester-caffeic acid amide hybrids as potential anticancer agents W. ... Triclosan-caffeic acid hybrids: Synthesis, leishmanicidal, trypanocidal and cytotoxic activities Elver Otero, Elisa García, ... Stereoselective Addition of Organometallic Reagents to a Chiral Acyclic Nitrone Derived from L-Erythrulose J.A. Marco, Juan ...
Nerolidol is an acyclic sesquiterpene found as a major constituent of several EOs such as Piper claussenianum and Burchardia ... Activation of the γ-aminobutyric acid (GABA) receptor system and the blockade of neuronal voltage-gated sodium channels (Na+ ... 89] evaluated the antinociceptive activity of nerolidol using the acetic acid-induced writhing test, the formalin test, and the ... The major constituents include the monoterpene bornyl acetate and the sesquiterpene valerenic acid, which is characteristic of ...
We assessed Zn-PVAs performance in preserving nucleic acids in spiked controls (Appendix). In addition, we had missing data in ... We created a directed acyclic graph on the basis of the variables included in the questionnaire where independent variables ... We detected target-specific nucleic acids from ,1 pathogen in 26% (127/488) of childrens stool specimens (Table 2), most ... we extracted total nucleic acids from ≈150 mg of the stool Zn-PVA mixture. We typically extracted specimens within 1-4 weeks of ...
  • Acrylates are derivatives of acrylic acid (the structural formula CH 2 =CHCO 2 H), including its salts and esters. (wellnessadvantage.com)
  • The present invention relates to a granular catalyst for the hydrolysis of amino nitriles and/or amino amides to amino acids or derivatives thereof, a process for the preparation of this catalyst and a method for the preparation of an am. (sumobrain.com)
  • This compound belongs to the class of organic compounds known as sugar acids and derivatives. (drugbank.com)
  • A convenient electrophile-electrophile cross-coupling of carboxylic acid derivatives and alkylpyridinium salts via C-N bond cleavage provides various functionalized ketones in very good yields. (organic-chemistry.org)
  • Glavač, D., Jerić, I. & Gredičak, M. (2019) Organocatalytic Synthesis of α,α-Diaryl Substituted α-Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction . (irb.hr)
  • The present invention relates to a process for in situ the preparation of mixtures of chelating agents by catalyzed reactions of diethanolamine derivatives with maleic acid and then with 2-halocarboxylic acid, to mixtures of chelating agents and methods using such chelating agents. (justia.com)
  • WO 97/45396 discloses N-bis- and N-tris-[(1,2-dicarboxy-ethoxy)-ethyl]-amine derivatives including N-bis-[(1,2-dicarboxy-ethoxy)-ethyl]-aspartic acid (also called aspartic acid diethoxy succinate or AES), and the use of these derivatives as chelating agents of metals, especially in connection with pulp bleaching. (justia.com)
  • These derivatives can be prepared by reacting di- or triethanolamine with an alkali metal or alkaline earth metal salt of maleic acid in the presence of a catalyst such as lanthanoid compounds, a nickel compound or alkaline earth metal compounds, e.g. calcium hydroxide or magnesium hydroxide. (justia.com)
  • Aryl-substituted primary alcohol/aldehyde/acid/ester/acetal derivatives, including unsaturated ones. (vcf-online.nl)
  • Application of the Miyaura-Hayashi rhodium-catalysed addition of aryl boronic acids to acyclic unsaturated esters featuring basic centres to yield γ-amino butyric acids incorporating a substituted β-phenyl group is described. (strath.ac.uk)
  • Benzyl alcohols/aldehydes/acids/esters/acetals. (vcf-online.nl)
  • Straight-chain primary aliphatic alcohols/aldehydes/acids, acetals and esters with esters containing saturated alcohols and acetals containing saturated aldehydes. (vcf-online.nl)
  • Branched-chain primary aliphatic alcohols/aldehydes/acids, acetal and esters with esters containing branched-chain alcohols and acetals containing branched-chain aldehydes. (vcf-online.nl)
  • alpha, beta-unsaturated (alkene or alkyne) straight-chain and branched-chain aliphatic primary alcohols/aldehydes/acids, acetals and esters with esters containing alpha, beta-unsaturated alcohol and acetal containing alpha, beta-unsaturated alcohols or aldehydes. (vcf-online.nl)
  • Non-conjugated and accumulated unsaturated straight-chain and branched-chain aliphatic primary alcohols/aldehydes/acids, acetals and esters with esters containing unsaturated alcohols and acetals containing unsaturated alcohols or aldehydes. (vcf-online.nl)
  • Esters may contain any acid component. (vcf-online.nl)
  • Primary alicyclic saturated and unsaturated alcohols/aldehydes/acids/acetals/esters with esters containing alicyclic alcohols. (vcf-online.nl)
  • Esters/acetals may contain aliphatic acyclic or alicylic acids or alcohol component. (vcf-online.nl)
  • Esters may contain aliphatic acyclic or alicyclic acid component. (vcf-online.nl)
  • Primary aliphatic saturated or unsaturated alcohols/aldehydes/acids/acetals/esters with a second primary, secondary or tertiary oxygenated functional group including aliphatic lactones. (vcf-online.nl)
  • Early developments in Lewis acid reagents focused on easily available compounds such as TiCl4, BF3, SnCl4, and AlCl3. (wikipedia.org)
  • Dipeptides are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. (hmdb.ca)
  • See also boiling points of hydrcarbons, alcohols and acids , densities for different kinds of organic compounds and density, boiling and melting points of nitrogen and sulfur compounds. (engineeringtoolbox.com)
  • These are compounds containing a saccharide unit which bears a carboxylic acid group. (drugbank.com)
  • Few organofluorine compounds exist naturally ( C&EN, May 22, page 12 ), meaning that almost all must be made. (acs.org)
  • Acid refers to the cations ionized in aqueous solution are all compounds of hydrogen ions, which can be divided into inorganic acids and organic acids. (guidechem.com)
  • Decanoic acid belongs to the class of organic compounds known as medium-chain fatty acids. (guidechem.com)
  • Palmitic acid, also known as palmitate or C16, belongs to the class of organic compounds known as long-chain fatty acids. (foodb.ca)
  • Nucleic Acids Res. (nih.gov)
  • New analogs of the commercial asymmetric monomethine cyanine dyes thiazole orange (TO) and thiazole orange homodimer (TOTO) with hydroxypropyl functionality were synthesized and their properties in the presence of different nucleic acids were studied. (mdpi.com)
  • The symposium has been inspired by the thematic issue " Nucleic Acid Chemistry " in the Open Access Beilstein Journal of Organic Chemistry, edited by Hans-Achim Wagenknecht. (beilstein-institut.de)
  • The Beilstein Organic Chemistry Symposium 2016 was inspired by the Thematic Series "Nucleic acid chemistry" in the Beilstein Journal of Organic Chemistry. (beilstein-institut.de)
  • Since the discovery of solid-phase DNA (and later RNA) synthesis by methods of organic chemistry, the field of nucleic acid chemistry exploded. (beilstein-institut.de)
  • Although nucleic acid chemistry seems to be already a mature part of organic and bioorganic chemistry, actual questions that are raised by research in biology and chemical biology give enough reasons to synthesize new nucleic acid probes and thereby further develop nucleic acid chemistry. (beilstein-institut.de)
  • These broad aspects of nucleic acid chemistry were covered by the topics of five different sessions that included 21 invited speakers. (beilstein-institut.de)
  • In the first session "new nucleic acid building blocks", Annemieke Madder reported on modified nucleic acids for crosslinks and Elmar Weinhold talked about sequence-specific labeling of DNA by methyltransferases. (beilstein-institut.de)
  • Sabine Müller described trinucleotide phosphoramidites and Michal Hocek allowed an insight into polymerase-assisted synthesis of modified nucleic acids. (beilstein-institut.de)
  • Hiroyuki Asanuma followed this path by a report on threolinol and serinol nucleic acid analogs and Jesper Wengel extended the topic by peptide-nucleic acid conjugates. (beilstein-institut.de)
  • The open end timeline in the evening after dinner allowed intense discussions about all aspects of nucleic acids by PhD researchers, postdocs and junior professors together with the invited speakers. (beilstein-institut.de)
  • The single session on Thursday was focused on light-driven and fluorescent functionalities and started with Nathan Luedtke talking about biorthogonal fluorescent reporters for nucleic acids in cells and Oliver Seitz focusing on enhanced hybridization probes for RNA imaging. (beilstein-institut.de)
  • The program on Friday started with the session "new nucleic acid architectures and base pairs" and comprised a presentation by Jens Müller on metal-mediated base pairing and a lecture by Clemens Richert on prebiotic aspects of peptido RNA formation. (beilstein-institut.de)
  • Andrea Rentmeister gave a chemical biology perspective on the 5'-cap and Snorri Sigurdsson described strategies for site-directed spin labeling of nucleic acids. (beilstein-institut.de)
  • Before this stage, the pre-RNA world may have been based on molecules called xeno nucleic acids (XNAs). (astrobiology.com)
  • They synthesized fragments of acyclic (non-circular) L-threoninol nucleic acid (L-aTNA), a molecule that is thought to have existed before RNA came to be. (astrobiology.com)
  • The paper, "Nonenzymatic polymerase-like template-directed synthesis of acyclic L-threoninol nucleic acid," was published online in the journal Nature Communications on February 5, 2021 at DOI: 10.1038s41467-021-21128-0. (astrobiology.com)
  • The tables and figures below show how the melting point changes with increasing carbon number up to C 33 for different kinds of hydrocarbons, alcohols and carboxylic acids. (engineeringtoolbox.com)
  • In general, branched-chain aliphatic acyclic alcohols are rapidly absorbed from the gastrointestinal tract. (europa.eu)
  • May also contain aliphatic acyclic or alicyclic ester or acetal component. (vcf-online.nl)
  • Palmitic acid is the first fatty acid produced during fatty acid synthesis and is the precursor to longer fatty acids. (hmdb.ca)
  • Alcohol and fatty acid stimulation of neurotensin release from rat small intestine. (umassmed.edu)
  • Acids with a methyl substituent located at an even-numbered carbon are extensively metabolized to CO2 via ß-oxidative cleavage in the fatty acid pathway. (europa.eu)
  • They also are substrates for ß-oxidation and cleavage in the amino acid and fatty acid pathways. (europa.eu)
  • Some dipeptides are known to have physiological or cell-signalling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. (hmdb.ca)
  • The production method according to the present invention is characterized in that a D-amino acid oxidase used in step 2 in the scheme shown below is a polypeptide selected from the below-mentioned polypeptides (a) to (c). (sumobrain.com)
  • Click chemistry is compatible with various protected amino acid side chains used in peptide synthesis. (genengnews.com)
  • As a result, we demonstrate that Δp K a is an experimental parameter to estimate increments in the carbonyl-carbonyl alignment, as determined by the amino acid or peptidyl context. (rsc.org)
  • H-Lys-NH2) amino acid amides. (umd.edu)
  • Electrostatic interactions between the tetraanionic 1 and 2 with the amino acid guests (in their N-acetylated, zwitterionic, or CO-NH2 forms) was demonstrated to dramatically influence the strength of the recognition process. (umd.edu)
  • According to the present invention it was surprisingly found that the free hydroxyl groups of bis-(2-hydroxyethyl)glycine or bis-(2-hydroxyethyl)methyl glycine, or salts thereof can easily and effectively be converted into other reactive ingredients by the addition of a maleate into the reaction containing a lanthanoid catalyst to yield an amino acid derivative substituted with succinic acid groups. (justia.com)
  • According to the number of hydrogen ions produced by acid molecule ionization, it can be divided into monobasic acid, dicarboxylic acid and ternary acid, and according to the presence or absence of oxygen atoms in acid molecule, it can be divided into oxygenated acid and anoxic acid. (guidechem.com)
  • These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms. (foodb.ca)
  • Peptides can also be made by inter- and intramolecular click reactions using azide or alkyne containing amino acids or building blocks during peptide synthesis. (genengnews.com)
  • Chapter 1 introduces cucurbit[n]urils and their molecular recognition properties toward amino acids, peptides, and Insulin. (umd.edu)
  • Chapter 2 describes the application of the acyclic CB[n], Calabadion 1 and 2 for the molecular recognition of amino acids, peptides, and Insulin. (umd.edu)
  • Fmoc- protected for solid phase synthesis), propargyl amino acids, PEG azide and alkynes (Maleimide-PEG3-Azide and acetylene PEG maleimide for pegylation), alkyne and azide containing chemical modification reagents (propargyl amine, 1-(2-nitrophenyl) propargyl alcohol, succinidyl-hex-5-ynoate, succinimidyl-4-azovalerate, pentynoic acid, 2-azido-3-methyl propanoic acid) and Diazo transfer reagents (imidazole-1-sulfonyl azide). (genengnews.com)
  • Topolovčan, N., Duplić, F. & Gredičak, M. (2021) Influence of N-Substitution in 3-Alkyl-3-hydroxyisoindolin-1-ones on the Stereoselectivity of Brønsted Acid-Catalyzed Synthesis of 3-Methyleneisoindolin-1-ones . (irb.hr)
  • Butyric Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This graph shows the total number of publications written about "Butyric Acid" by people in this website by year, and whether "Butyric Acid" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Butyric Acid" by people in Profiles. (umassmed.edu)
  • At low dilutions, it has a pleasant, fruity taste clear colorless to pale yellowish liquidChEBI: A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. (guidechem.com)
  • This hydrolysis makes read-across to butyric acid a relevant approach for every toxicological test, as water is present in all of them. (europa.eu)
  • In reactions with polar mechanisms, Lewis acid catalysis often involves binding of the catalyst to Lewis basic heteroatoms and withdrawing electron density, which in turn facilitates heterolytic bond cleavage (in the case of Friedel-Crafts reaction) or directly activates the substrate toward nucleophilic attack (in the case of carbonyl addition reactions). (wikipedia.org)
  • Among the types of reactions that can be catalyzed by Lewis acids, those with carbonyl-containing substrates have received the greatest amount of attention. (wikipedia.org)
  • The use of an arylvinyl α-carbonyl acid ester compound (I) as a photoinitiator in LED photopolymerization and a preparation method therefor, which relate to the field of polymer photocuring, and are provided on the basis of the problems. (sumobrain.com)
  • Urocanic Acid is an imidazole compound . (wellnessadvantage.com)
  • The present invention relates to a method for preparing an ester thiol compound by reacting a polyalcohol and a mercaptocarboxylic acid and to an optical resin or optical lens obtained therefrom having superior optical properties. (sumobrain.com)
  • It is an acid compound found in citrus fruits. (sdsc.edu)
  • The common acids are sulfuric acid, hydrochloric acid, nitric acid and so on. (guidechem.com)
  • Alternatively, asymmetric autocatalysis will be explored using simple cyclic and acyclic acceptor molecules and amine donors to generate e.g. amino acids. (noorderlink.nl)
  • In Lewis acid catalysis of organic reactions, a metal-based Lewis acid acts as an electron pair acceptor to increase the reactivity of a substrate. (wikipedia.org)
  • The Lewis acid bind via a donor-acceptor interaction to the dienophile and via that mechanism polarizes occupied orbital density away from the reactive C=C double bond of the dienophile towards the Lewis acid. (wikipedia.org)
  • Beriša, A. & Gredičak, M. (2023) Chiral phosphoric acid-catalyzed Friedel-Crafts reaction of 2,5-disubstituted and 2-monosubstituted pyrroles with isoindolinone-derived ketimines . (irb.hr)
  • Many classical reactions involving carbon-carbon or carbon-heteroatom bond formation can be catalyzed by Lewis acids. (wikipedia.org)
  • A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester. (umassmed.edu)
  • The subject product, 4-Chlorophenyl chloroformate, is a halogenated aromatic ester of a formic acid derivative (halogenated) indicated for use as a pharmaceutical intermediate. (faqs.org)
  • Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism. (guidechem.com)
  • The amount of methylmalonic acid and succinic acid excreted in urine was determined by a paper chromatographic method. (europa.eu)
  • In the period prior to test substance administration, the background excretion of methylmalonic acid and succinic acid was determined to be between 0.33 to 1.76 mg/day and 4.1 to 7.0 mg/day respectively. (europa.eu)
  • During administration, the amounts of acids excreted increased to maximum values of 17.9 g/day for methylmalonic acid during the third sampling period (day 5 and 6 of administration) and of 73.7 g/day for succinic acid during the second sampling period (day 3 and 4 of administration). (europa.eu)
  • succinic acid 9.6 mg/day) (Thomas, 1958). (europa.eu)
  • Palmitic acid, or hexadecanoic acid, is one of the most common saturated fatty acids found in animals, plants, and microorganisms. (hmdb.ca)
  • Chapter 3 introduces a new acyclic CB[n] featuring a central glycoluril trimer with sulfonated triptycene aromatic sidewalls. (umd.edu)
  • Aluminium salts of palmitic acid and naphthenic acid were combined during World War II to produce napalm. (hmdb.ca)
  • The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. (sdsc.edu)
  • It has now been surprisingly found that mixtures of chelating agents having a diethanol amine backbone can be effectively prepared by lanthanoid-catalysed reaction of bis-(2-hydroxyethyl)glycine or bis-(2-hydroxyethyl)methyl glycine, or salts thereof with a maleate followed by a subsequent lanthanide-catalyzed reaction with a 2-halocarboxylic acid. (justia.com)
  • Citric acid is a weak organic tricarboxylic acid found in citrus fruits. (guidechem.com)
  • We observed conservative Δp K a s for acyclic amino acids (2.2-3.0 kJ mol −1 ), whereas in the case of alicyclic amino acids, the experimental values revealed a strong dependency on the structural context (1.5-4.4 kJ mol −1 ). (rsc.org)
  • Acids can react with bases or alkaline oxides to form salt and water, or with certain metals to form salt and hydrogen, and the indicator can be discolored when the aqueous solution contains acids. (guidechem.com)
  • In pulp bleaching liquors, iron and manganese ions are desired to be trapped by a chelating agent, thereby inhibiting these metal ions from catalyzing the decomposition of the bleaching agents, hydrogen peroxide or peroxy acids. (justia.com)
  • Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. (sdsc.edu)
  • Citric acid is a natural preservative and food tartness enhancer. (guidechem.com)
  • The acidity of N -acyl amino acids is dependent upon the rotameric state of the amide bond. (rsc.org)
  • More recently, Lewis acid catalysts with chiral ligands have become an important class of tools for asymmetric catalysis. (wikipedia.org)
  • Glavač, D. & Gredičak, M. (2022) Construction of chiral Betti base precursors containing a congested quaternary stereogenic center via chiral phosphoric acid-catalyzed arylation of isoindolinone-derived ketimines . (irb.hr)
  • The dichotomy can have important consequences in some reactions, as in the case of Lewis acid-promoted acetal substitution reactions, where the SN1 and SN2 mechanisms shown below may give different stereochemical outcomes. (wikipedia.org)
  • In addition, the Lewis acid catalyst also increases the asynchronicity of the Diels-Alder reaction, making the occupied π-orbital located on the C=C double bond of the dienophile asymmetric. (wikipedia.org)
  • Challenges in the development of Lewis acid catalysis include inefficient catalyst turnover (caused by catalyst affinity for the product) and the frequent requirement of two-point binding for stereoselectivity, which often necessitates the use of auxiliary groups. (wikipedia.org)
  • The metabolic fate of isobutyric acid (IBA) was investigated by oral (gavage) administration of radiolabelled [1-14C]isobutyric acid to groups of 4 male CD rats at doses of 4, 40, and 400 mg/kg bw and to 4 female CD rats at 400 mg/kg bw. (europa.eu)
  • Our strategy is an attractive system for experimenting with the construction of artificial life and the development of highly functional biological tools composed of acyclic XNA," says Murayama. (astrobiology.com)
  • This parameter is also important in understanding the roles of amino acids in both protein folding and translation in biological systems as well as their evolutionary appearance in the genetic code. (rsc.org)