Acidaminococcus: A genus of gram-negative bacteria in the family ACIDAMINOCOCCACEAE, isolated from the INTESTINES of PIGS and humans.Veillonellaceae: A family of gram-negative bacteria, in the phylum FIRMICUTES.Coenzyme A-Transferases: Enzymes which transfer coenzyme A moieties from acyl- or acetyl-CoA to various carboxylic acceptors forming a thiol ester. Enzymes in this group are instrumental in ketone body metabolism and utilization of acetoacetate in mitochondria. EC 2.8.3.Aconitic AcidGram-Negative Anaerobic Bacteria: A large group of anaerobic bacteria which show up as pink (negative) when treated by the Gram-staining method.Gram-Negative Anaerobic Cocci: A group of anaerobic coccoid bacteria that show up as pink (negative) when treated by the gram-staining method.GlutaratesVeillonella: A genus of gram-negative, anaerobic cocci parasitic in the mouth and in the intestinal and respiratory tracts of man and other animals.Bacteria, AnaerobicHydro-Lyases: Enzymes that catalyze the breakage of a carbon-oxygen bond leading to unsaturated products via the removal of water. EC 4.2.1.Carboxy-Lyases: Enzymes that catalyze the addition of a carboxyl group to a compound (carboxylases) or the removal of a carboxyl group from a compound (decarboxylases). EC 4.1.1.Biotin: A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.Clostridium: A genus of motile or nonmotile gram-positive bacteria of the family Clostridiaceae. Many species have been identified with some being pathogenic. They occur in water, soil, and in the intestinal tract of humans and lower animals.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
(1/5) Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans.

NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase (HGDH) catalyses the reduction of 2-oxoglutarate to (R)-2-hydroxyglutarate and belongs to the d-2-hydroxyacid NAD(+)-dependent dehydrogenase (d-2-hydroxyacid dehydrogenase) protein family. Its crystal structure was determined by phase combination to 1.98 A resolution. Structure-function relationships obtained by the comparison of HGDH with other members of the d-2-hydroxyacid dehydrogenase family give a chemically satisfying view of the substrate stereoselectivity and catalytic requirements for the hydride transfer reaction. A model for substrate recognition and turnover is discussed. The HGDH active site architecture is structurally optimized to recognize and bind the negatively charged substrate 2-oxoglutarate. The structural position of the side chain of Arg52, and its counterparts in other family members, strongly correlates with substrate specificity towards substitutions at the C3 atom (linear or branched substrates). Arg235 interacts with the substrate's alpha-carboxylate and carbonyl groups, having a dual role in both substrate binding and activation, and the gamma-carboxylate group can dock at an arginine cluster. The proton-relay system built up by Glu264 and His297 permits His297 to act as acid-base catalyst and the 4Re-hydrogen from NADH is transferred as hydride to the carbonyl group Si-face leading to the formation of the correct enantiomer (R)-2-hydroxyglutarate.  (+info)

(2/5) Acidaminococcus intestini sp. nov., isolated from human clinical samples.

Eleven strains of a hitherto unknown, Gram-negative, anaerobic coccus were recovered from various human clinical samples of patients hospitalized in two geographically distant French hospitals. These strains displayed the morphology and growth characteristics of those related to the genus Acidaminococcus. The clinical isolates shared at least 99.9 and 99.7 % of their nucleotide positions in the 16S and 23S rRNA gene sequences, respectively. They displayed 95.6 and 88.9 % 16S and 23S rRNA gene sequence similarities, respectively, with Acidaminococcus fermentans. The 16S rRNA-based phylogeny revealed that all the clinical isolates grouped in a statistically well supported cluster separate from A. fermentans. Enzymic activity profiles as well as metabolic end product patterns, including propionic acid production, differentiated the novel bacteria from A. fermentans. Finally, phenotypic, genotypic and phylogenetic data, including large-scale chromosome structure and DNA G+C content, supported the proposal of a novel species of the genus Acidaminococcus, for which the name Acidaminococcus intestini sp. nov. is proposed. The type strain is ADV 255.99(T) (=AIP 283.01(T)=CIP 108586(T)=CCUG 50930(T)).  (+info)

(3/5) Spectroscopic evidence for an all-ferrous [4Fe-4S]0 cluster in the superreduced activator of 2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans.

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(4/5) An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases.

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(5/5) Complete genome sequence of Acidaminococcus intestini RYC-MR95, a Gram-negative bacterium from the phylum Firmicutes.

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*  Acidaminococcus
The name Acidaminococcus derives from: New Latin noun acidum (from Latin adjective acidus, sour), an acid; New Latin adjective ... Acidaminococcus is a genus in the phylum Firmicutes (Bacteria), whose members are anaerobic diplococci that can use amino acids ... Acidaminococcus entry in LPSN [Euzéby, J.P. (1997). "List of Bacterial Names with Standing in Nomenclature: a folder available ... "Acidaminococcus intestini sp. Nov., isolated from human clinical samples". International Journal of Systematic and Evolutionary ...
*  Negativicutes
2015 Acidaminococcus Rogosa 1969 emend. Jumas-Bilak et al. 2007 Phascolarctobacterium Del Dot et al. 1994 Succiniclasticum van ... Campbell C, Sutcliffe IC, Gupta RS (2014). "Comparative proteome analysis of Acidaminococcus intestini supports a relationship ...
*  Glutaconate CoA-transferase
Buckel W, Dorn U, Semmler R (1981). "Glutaconate CoA-transferase from Acidaminococcus fermentans". Eur. J. Biochem. 118 (2): ...
*  CRISPR/Cpf1
Two candidate enzymes from Acidaminococcus and Lachnospiraceae display efficient genome-editing activity in human cells. A ...
*  Chloroflexi (class)
Campbell C, Sutcliffe IC, Gupta RS (2014). "Comparative proteome analysis of Acidaminococcus intestini supports a relationship ...
*  Deinococcus-Thermus
Campbell C, Sutcliffe IC, Gupta RS (2014). "Comparative proteome analysis of Acidaminococcus intestini supports a relationship ...
*  Sodium-transporting carboxylic acid decarboxylase
The high resolution crystal structure of the α-subunit of the glutaconyl-CoA decarboxylase (Gcdα) of Acidaminococcus fermentans ... "The sodium ion translocating glutaconyl-CoA decarboxylase from Acidaminococcus fermentans: cloning and function of the genes ...
*  Grass tetany
Ability of Acidaminococcus fermentans to oxidize trans-aconitate and decrease the accumulation of tricarballylate, a toxic end ...
*  Cpf1
Out of 16 Cpf1-family proteins, scientists identified two candidate enzymes from Acidaminococcus and Lachnospiraceae, with ...
*  List of MeSH codes (B03)
Acidaminococcus MeSH B03.440.425.410.096.755 --- Pectinatus MeSH B03.440.425.410.096.877 --- Selenomonas MeSH B03.440.425.410. ...
Nomenclatural changes validly published (or published) in the 2007 issues of the IJSEM  Nomenclatural changes validly published (or published) in the 2007 issues of the IJSEM
Acidaminococcus Rogosa 1969 emend. Jumas-Bilak et al. 2007. (Part 10) Acidaminococcus intestini Jumas-Bilak et al. 2007, sp. ...
more infohttp://www.bacterio.net/-changes-2007.html
Acidaminococcus - Wikipedia  Acidaminococcus - Wikipedia
The name Acidaminococcus derives from: New Latin noun acidum (from Latin adjective acidus, sour), an acid; New Latin adjective ... Acidaminococcus is a genus in the phylum Firmicutes (Bacteria), whose members are anaerobic diplococci that can use amino acids ... Acidaminococcus entry in LPSN [Euzéby, J.P. (1997). "List of Bacterial Names with Standing in Nomenclature: a folder available ... "Acidaminococcus intestini sp. Nov., isolated from human clinical samples". International Journal of Systematic and Evolutionary ...
more infohttps://en.wikipedia.org/wiki/Acidaminococcus
KEGG PATHWAY: Nucleotide excision repair - Acidaminococcus fermentans  KEGG PATHWAY: Nucleotide excision repair - Acidaminococcus fermentans
Nucleotide excision repair - Acidaminococcus fermentans [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show ...
more infohttp://www.genome.jp/kegg-bin/show_pathway?afn03420
Comparative proteome analysis of Acidaminococcus intestini supports a relationship between outer membrane biogenesis in...  Comparative proteome analysis of Acidaminococcus intestini supports a relationship between outer membrane biogenesis in...
D'Auria G, Galan J-C, Rodriguez-Alcayna M, Moya A, Baquero F, Latorre A (2011) Complete genome sequence of Acidaminococcus ... Comparative proteome analysis of Acidaminococcus intestini supports a relationship between outer membrane biogenesis in ... we have performed a whole proteome BLAST analysis of Acidaminococcus intestini, which indicates that a substantial proportion ( ...
more infohttps://link.springer.com/article/10.1007%2Fs00203-014-0964-4
Acidaminococcus sp. CRISPR/Cpf1 monoclonal antibody	  Acidaminococcus sp. CRISPR/Cpf1 monoclonal antibody
Acidaminococcus sp. CRISPR/Cpf1 monoclonal antibody DATASHEET. Monoclonal antibody raised in mouse against Acidaminococcus sp ... Request a quote for a bulk order for Acidaminococcus sp. CRISPR/Cpf1 monoclonal antibody. Please fill out the form here below. ... Monoclonal antibody raised in mouse against Acidaminococcus sp. (As) Cpf1 (CRISPR from Prevotella and Francisella 1) using a ... Diagenode strongly recommends using this: Acidaminococcus sp. CRISPR/Cpf1 monoclonal antibody (Diagenode Cat# C15200234-100 ...
more infohttps://www.diagenode.com/en/p/acidaminococcus-sp-crisprcpf1-monoclonal-antibody-100-ul
RCSB PDB 









- 1POI: CRYSTAL STRUCTURE OF GLUTACONATE COENZYME A-TRANSFERASE FROM ACIDAMINOCOCCUS FERMENTANS TO 2.55...  RCSB PDB - 1POI: CRYSTAL STRUCTURE OF GLUTACONATE COENZYME A-TRANSFERASE FROM ACIDAMINOCOCCUS FERMENTANS TO 2.55...
Glutaconate CoA-transferase from Acidaminococcus fermentans: the crystal structure reveals homology with other CoA-transferases ... CRYSTAL STRUCTURE OF GLUTACONATE COENZYME A-TRANSFERASE FROM ACIDAMINOCOCCUS FERMENTANS TO 2.55 ANGSTOMS RESOLUTION. *DOI: ...
more infohttp://www.rcsb.org/pdb/explore/litView.do?structureId=1POI
Acidaminococcus sp. CRISPR/Cpf1 Rabbit Polyclonal Antibody | Diagenode	  Acidaminococcus sp. CRISPR/Cpf1 Rabbit Polyclonal Antibody | Diagenode
Polyclonal antibody raised in rabbit against Acidaminococcus sp. (As) Cpf1 (CRISPR from Prevotella and Francisella 1) using a ... Acidaminococcus sp. CRISPR/Cpf1 polyclonal antibody DATASHEET. Polyclonal antibody raised in rabbit against Acidaminococcus sp ... Acidaminococcus sp. CRISPR/Cpf1 polyclonal antibody. PUB FLASH. DNA methylation of the Tacr2 gene in a CUMS model of depr.... ... Request a quote for a bulk order for Acidaminococcus sp. CRISPR/Cpf1 polyclonal antibody. Please fill out the form here below. ...
more infohttps://www.diagenode.com/en/p/acidaminococcus-sp-crispr-cpf1-polyclonal-antibody
infA protein (Acidaminococcus intestini) - STRING interaction network  infA protein (Acidaminococcus intestini) - STRING interaction network
2007, Acidaminococcus intestini RyC-MR95, Acidaminococcus intestini strain RyC-MR95, Acidaminococcus sp. ADV 255.99 ... Acidaminococcus intestini. NCBI taxonomy Id: 568816. Other names: A. intestini, A. intestini RyC-MR95, Acidaminococcus ... intestini, Acidaminococcus intestini Jumas-Bilak et al. ... "infA" - Translation initiation factor IF-1 in Acidaminococcus ...
more infohttps://string-db.org/network/568816.Acin_2316
alr protein (Acidaminococcus intestini) - STRING interaction network  alr protein (Acidaminococcus intestini) - STRING interaction network
2007, Acidaminococcus intestini RyC-MR95, Acidaminococcus intestini strain RyC-MR95, Acidaminococcus sp. ADV 255.99 ... Acidaminococcus intestini. NCBI taxonomy Id: 568816. Other names: A. intestini, A. intestini RyC-MR95, Acidaminococcus ... intestini, Acidaminococcus intestini Jumas-Bilak et al. ...
more infohttps://string-db.org/network/568816.Acin_1813
Transfer of Veillonella Prévot and Acidaminococcus Rogosa from Neisseriaceae to Veillonellaceae fam. nov., and the Inclusion of...  Transfer of Veillonella Prévot and Acidaminococcus Rogosa from Neisseriaceae to Veillonellaceae fam. nov., and the Inclusion of...
It is herein proposed that Veillonella Prévot 1933 and Acidaminococcus Rogosa 1969 be transferred from Neisseriaceae and be ... Transfer of Veillonella Prévot and Acidaminococcus Rogosa from Neisseriaceae to Veillonellaceae fam. nov., and the Inclusion of ... It is herein proposed that Veillonella Prévot 1933 and Acidaminococcus Rogosa 1969 be transferred from Neisseriaceae and be ...
more infohttps://www.microbiologyresearch.org/content/journal/ijsem/10.1099/00207713-21-3-231
Negativicutes - Wikipedia  Negativicutes - Wikipedia
2015 Acidaminococcus Rogosa 1969 emend. Jumas-Bilak et al. 2007 Phascolarctobacterium Del Dot et al. 1994 Succiniclasticum van ... Campbell C, Sutcliffe IC, Gupta RS (2014). "Comparative proteome analysis of Acidaminococcus intestini supports a relationship ...
more infohttps://en.wikipedia.org/wiki/Negativicutes
RCSB PDB 









for 1PIX  RCSB PDB for 1PIX
Acidaminococcus fermentans EC#: 4.1.1.70 IUBMB Gene Name(s): gcdA Acfer_1817 ...
more infohttp://www.rcsb.org/pdb/explore/biologyAndChemistry.do?structureId=1PIX
UniProt: R7K8X6 9FIRM  UniProt: R7K8X6 9FIRM
Acidaminococcus sp. CAG:917. OC Bacteria; Firmicutes; Negativicutes; Acidaminococcales; OC Acidaminococcaceae; Acidaminococcus ...
more infohttp://www.genome.jp/dbget-bin/www_bget?uniprot:R7K8X6_9FIRM
Efficient targeted DNA editing and replacement in Chlamydomonas reinhardtii using Cpf1 ribonucleoproteins and single-stranded...  Efficient targeted DNA editing and replacement in Chlamydomonas reinhardtii using Cpf1 ribonucleoproteins and single-stranded...
As Cas9 activity in planta is correlated with activity in mammalian cells (40), we assayed the activity of Acidaminococcus Cpf1 ... A) CRISPR nuclease orthologs Acidaminococcus sp. Cpf1 (AsCpf1), Lachnospiraceae bacterium Cpf1 (LbCpf1), and Streptococcus ... Plasmid vectors containing human-codon optimized Cpf1 from Acidaminococcus sp. BV3L6 (AsCpf1) and Lachnospiraceae bacterium ...
more infohttp://www.pnas.org/content/114/51/13567
Prokaryota - Wikispecies  Prokaryota - Wikispecies
Genus Acidaminococcus [II]. *Genus Megasphaera [III]. *Genus Veillonella [I]. *Section 9. Rickettsias and Chlamydias *Order ...
more infohttps://species.wikimedia.org/wiki/Prokaryota
Addgene: pYPQ223 (dAsCpf1-SRDX)  Addgene: pYPQ223 (dAsCpf1-SRDX)
Acidaminococcus sp. BV3L6 * Mutation. D908A * Tag / Fusion Protein *SRDX repressor and NLS ...
more infohttps://www.addgene.org/86209/
CAZy - Bacteria  CAZy - Bacteria
Acidaminococcus intestini RyC-MR95 Taxonomy ID : 568816. Lineage: cellular organisms; Bacteria; Terrabacteria group; Firmicutes ...
more infohttp://www.cazy.org/b1883.html
Addgene: pY010 (pcDNA3.1-hAsCpf1)  Addgene: pY010 (pcDNA3.1-hAsCpf1)
Acidaminococcus_sp_BV3L6 * Insert Size (bp). 3921 * Promoter CMV * Tag / Fusion Protein *NLS-3xHA (C terminal on insert) ...
more infohttp://www.addgene.org/69982/
Advanced Catalog Search  Advanced Catalog Search
HM-853 Acidaminococcus sp. HPA0509. M. Bacteria BEI Level 2 64103222 BEI Number. HM-860 Pseudomonas sp. HPB0071 ...
more infohttps://www.beiresources.org/Collection/4/Human-Microbiome-Project.aspx?f_instockflag=In+Stock%23~%23Temporarily+Out+of+Stock&page=1
A gene-targeted approach to investigate the intestinal butyrate-producing bacterialcommunity | Microbiome | Full Text  A gene-targeted approach to investigate the intestinal butyrate-producing bacterialcommunity | Microbiome | Full Text
... in which there was a predominance of butgenes that are similar to reference genes from Acidaminococcus sp.,Eubacterium sp., ... Quantitative PCR analysis of butyryl-CoA:acetate CoA-transferase( but ) and butyrate kinase( buk ) genes. But ofAcidaminococcus ... For the primers targeting Acidaminococcus (butgene) and C. butyricum, (16S rRNA gene), instead of a pure culture,a patient ... Similarly, many more 16S rRNA genesequences were assigned to Acidaminococcus sp., Anaerostipes sp.,Coprococcus sp. and ...
more infohttps://microbiomejournal.biomedcentral.com/articles/10.1186/2049-2618-1-8
Formic Acid - DrugBank  Formic Acid - DrugBank
Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / VR4). UTranscriptional regulator, IclR family. Not Available. ...
more infohttps://www.drugbank.ca/drugs/DB01942
Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells | Genome Biology | Full...  Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells | Genome Biology | Full...
Notably, the Cpf1 nucleases from Acidaminococcus sp. BV3L6 and Lachnospiraceae bacterium ND2006 (AsCpf1 and LbCpf1, ... Notably, the Cpf1 nucleases from Acidaminococcus sp. BV3L6 and Lachnospiraceae bacterium ND2006 (AsCpf1 and LbCpf1, ... from Acidaminococcus sp. BV3L6 and Lachnospiraceae bacterium ND2006 (AsCpf1 and LbCpf1, respectively) across a plethora of ...
more infohttps://genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1445-x