Acidaminococcus
Coenzyme A-Transferases
Gram-Negative Anaerobic Bacteria
Gram-Negative Anaerobic Cocci
Veillonella
Hydro-Lyases
Carboxy-Lyases
Biotin
Clostridium
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans. (1/5)
NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase (HGDH) catalyses the reduction of 2-oxoglutarate to (R)-2-hydroxyglutarate and belongs to the d-2-hydroxyacid NAD(+)-dependent dehydrogenase (d-2-hydroxyacid dehydrogenase) protein family. Its crystal structure was determined by phase combination to 1.98 A resolution. Structure-function relationships obtained by the comparison of HGDH with other members of the d-2-hydroxyacid dehydrogenase family give a chemically satisfying view of the substrate stereoselectivity and catalytic requirements for the hydride transfer reaction. A model for substrate recognition and turnover is discussed. The HGDH active site architecture is structurally optimized to recognize and bind the negatively charged substrate 2-oxoglutarate. The structural position of the side chain of Arg52, and its counterparts in other family members, strongly correlates with substrate specificity towards substitutions at the C3 atom (linear or branched substrates). Arg235 interacts with the substrate's alpha-carboxylate and carbonyl groups, having a dual role in both substrate binding and activation, and the gamma-carboxylate group can dock at an arginine cluster. The proton-relay system built up by Glu264 and His297 permits His297 to act as acid-base catalyst and the 4Re-hydrogen from NADH is transferred as hydride to the carbonyl group Si-face leading to the formation of the correct enantiomer (R)-2-hydroxyglutarate. (+info)Acidaminococcus intestini sp. nov., isolated from human clinical samples. (2/5)
Eleven strains of a hitherto unknown, Gram-negative, anaerobic coccus were recovered from various human clinical samples of patients hospitalized in two geographically distant French hospitals. These strains displayed the morphology and growth characteristics of those related to the genus Acidaminococcus. The clinical isolates shared at least 99.9 and 99.7 % of their nucleotide positions in the 16S and 23S rRNA gene sequences, respectively. They displayed 95.6 and 88.9 % 16S and 23S rRNA gene sequence similarities, respectively, with Acidaminococcus fermentans. The 16S rRNA-based phylogeny revealed that all the clinical isolates grouped in a statistically well supported cluster separate from A. fermentans. Enzymic activity profiles as well as metabolic end product patterns, including propionic acid production, differentiated the novel bacteria from A. fermentans. Finally, phenotypic, genotypic and phylogenetic data, including large-scale chromosome structure and DNA G+C content, supported the proposal of a novel species of the genus Acidaminococcus, for which the name Acidaminococcus intestini sp. nov. is proposed. The type strain is ADV 255.99(T) (=AIP 283.01(T)=CIP 108586(T)=CCUG 50930(T)). (+info)Spectroscopic evidence for an all-ferrous [4Fe-4S]0 cluster in the superreduced activator of 2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans. (3/5)
(+info)An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases. (4/5)
(+info)Complete genome sequence of Acidaminococcus intestini RYC-MR95, a Gram-negative bacterium from the phylum Firmicutes. (5/5)
(+info)UniProt/TrEMBL: G4Q3V8 ACIIR
Nomenclatural changes validly published (or published) in the 2007 issues of the IJSEM
UniProt: R7K8X6 9FIRM
Medroxyprogesterone acetate tablets 10mg - Budesonida oral efectos secundarios
Glandulae intestini crassi | definition of glandulae intestini crassi by Medical dictionary
RCSB PDB
- 1POI: CRYSTAL STRUCTURE OF GLUTACONATE COENZYME A-TRANSFERASE FROM ACIDAMINOCOCCUS FERMENTANS TO 2.55...
Wilson Audio Specialties Alexandria XLF loudspeaker | Stereophile.com
Wilson Audio Specialties Alexandria XLF loudspeaker | Stereophile.com
Ottawa | national capital, Canada | Britannica.com
Evaluation of the detection of Mycobacterium tuberculosis with metabolic activity in culture-negative human clinical samples
Seralab - The complete resource for all biologicals
Seralab - The complete resource for all biologicals
សារពាង្គកាយ - វិគីភីឌា
Human Metabolome Database: HMDB0001290 (Glutaconyl-CoA) Protein Associations
Human Metabolome Database: HMDB0001290 (Glutaconyl-CoA) Protein Associations
Bergeys Manual® of Systematic Bacteriology | Springer for Research & Development
we quickly defend ourselves | MidTown Hotel Hue
A comparative study of short- and long-TE <sup>1</sup>H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain...
Acidaminococcus
... is a genus in the phylum Bacillota (Bacteria), whose members are anaerobic diplococci that can use amino acids ... The name Acidaminococcus derives from: New Latin noun acidum (from Latin adjective acidus, sour), an acid; New Latin adjective ... "Acidaminococcus". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved 2022-09-09. Sayers; et al. " ... "Acidaminococcus". National Center for Biotechnology Information (NCBI) taxonomy database. Retrieved 2022-09-09. "The LTP". ...
Glutaconate CoA-transferase
Buckel W, Dorn U, Semmler R (1981). "Glutaconate CoA-transferase from Acidaminococcus fermentans". Eur. J. Biochem. 118 (2): ...
Cas12a
Two candidate enzymes from Acidaminococcus and Lachnospiraceae display efficient genome-editing activity in human cells. A ...
Deinococcota
Campbell C, Sutcliffe IC, Gupta RS (2014). "Comparative proteome analysis of Acidaminococcus intestini supports a relationship ...
Chloroflexia
Campbell C, Sutcliffe IC, Gupta RS (2014). "Comparative proteome analysis of Acidaminococcus intestini supports a relationship ...
Negativicutes
Campbell C, Sutcliffe IC, Gupta RS (2014). "Comparative proteome analysis of Acidaminococcus intestini supports a relationship ...
Ferredoxin
... cluster-containing ferredoxin as an alternative electron donor for 2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus ...
Sodium-transporting carboxylic acid decarboxylase
The high resolution crystal structure of the α-subunit of the glutaconyl-CoA decarboxylase (Gcdα) of Acidaminococcus fermentans ... "The sodium ion translocating glutaconyl-CoA decarboxylase from Acidaminococcus fermentans: cloning and function of the genes ...
Grass tetany
Ability of Acidaminococcus fermentans to oxidize trans-aconitate and decrease the accumulation of tricarballylate, a toxic end ...
Butyryl-CoA
... of Acidaminococcus fermentans". The Journal of Biological Chemistry. 289 (8): 5145-5157. doi:10.1074/jbc.M113.521013. PMC ...
Syntrophy
Amino acid fermenting anaerobes such as Clostridium species, Peptostreptococcus asacchaarolyticus, Acidaminococcus fermentans ...
List of MeSH codes (B03)
Acidaminococcus MeSH B03.440.425.410.096.755 - Pectinatus MeSH B03.440.425.410.096.877 - Selenomonas MeSH B03.440.425.410. ...
Complete genome sequence of acidaminococcus fermentans type strain (VR4 <sup>T<...
Acidaminococcus fermentans (Rogosa 1969) is the type species of the genus Acidaminococ-cus, and is of phylogenetic interest ... abstract = "Acidaminococcus fermentans (Rogosa 1969) is the type species of the genus Acidaminococ-cus, and is of phylogenetic ... N2 - Acidaminococcus fermentans (Rogosa 1969) is the type species of the genus Acidaminococ-cus, and is of phylogenetic ... AB - Acidaminococcus fermentans (Rogosa 1969) is the type species of the genus Acidaminococ-cus, and is of phylogenetic ...
Fecal Microbiota Transplant in Children With and Without IBD
Gut Reaction: Environmental Effects on the Human Microbiota | Environmental Health Perspectives | Vol. 117, No. 5
Kinetic Basis for DNA Target Specificity of CRISPR-Cas12a
The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium...
Superimposing Acidaminococcus fermentans EtfAB onto C. difficile EtfAB/Bcd reveals a rotation of domain II of nearly 80°. ... Rapid kinetics reveal surprising flavin chemistry in bifurcating electron transfer flavoprotein from Acidaminococcus fermentans ... of Acidaminococcus fermentans. Chowdhury NP, Mowafy AM, Demmer JK, Upadhyay V, Koelzer S, Jayamani E, Kahnt J, Hornung M, ...
'Enterococcus timonensis' sp. nov., 'Actinomyces marseillensis' sp. nov., 'Leptotrichia massiliensis' sp. nov., 'Actinomyces...
Startseite | Max-Planck-Institut für Biochemie
Publication Detail
Microbial co-occurrence complicates associations of gut microbiome with US immigration, dietary intake and obesity | Genome...
For example, Acidaminococcus which was associated with obesity in the current study and other populations [40, 41] was found to ... 3B), since Acidaminococcus is known to use amino acids as energy source [42]. However, it remains unknown how increased gut ... Among six bacteria outside of clusters A and B, Acidaminococcus and Parasutterella were associated both with higher BMI and ... increased Acidaminococcus, decreased Roseburia, and Prevotella), potentially related to westernized diet during acculturation ...
IMMUNOTHERAPEUTIC METHODS AND COMPOSITIONS - KING S COLLEGE LONDON
TREE NUMBER DESCRIPTOR
Name Taxonomy in SILVA v123
Genetic editing and interrogation with Cpf1 and caged truncated pre-tRNA-like crRNA in mammalian cells | Cell Discovery
DeCS
MeSH Browser
Acidaminococcus Preferred Term Term UI T540963. Date05/15/2003. LexicalTag NON. ThesaurusID NLM (2004). ... Acidaminococcus Preferred Concept UI. M0449492. Registry Number. txid904. Scope Note. A genus of gram-negative bacteria in the ... Acidaminococcus. Tree Number(s). B03.353.250. B03.440.425.410.073. Unique ID. D045850. RDF Unique Identifier. http://id.nlm.nih ...
MeSH Browser
Acidaminococcus Preferred Term Term UI T540963. Date05/15/2003. LexicalTag NON. ThesaurusID NLM (2004). ... Acidaminococcus Preferred Concept UI. M0449492. Registry Number. txid904. Scope Note. A genus of gram-negative bacteria in the ... Acidaminococcus. Tree Number(s). B03.353.250. B03.440.425.410.073. Unique ID. D045850. RDF Unique Identifier. http://id.nlm.nih ...
Code System Concept
Genome editing (CRISPR/Cas9) | Diagenode
MicrobiomePrescription
Publication Year: 2018 / Subject term: digestive system - PubAg Search Results
4.2 Family members | Personal Science Guide to the Microbiome
Clostridiales
This page is a Tree of Life Branch Page.. Each ToL branch page provides a synopsis of the characteristics of a group of organisms representing a branch of the Tree of Life. The major distinction between a branch and a leaf of the Tree of Life is that each branch can be further subdivided into descendent branches, that is, subgroups representing distinct genetic lineages.. For a more detailed explanation of the different ToL page types, have a look at the Structure of the Tree of Life page.. close box ...
Genomes encoding eukaryotic-like proteins | EffectiveDB
Asthma | Disease | MetaBiom
18 (32%) : Acidaminococcus , Actinomyces , Alistipes , Bacteroides , Escherichia coli , Eubacterium , Gemella , Haemophilus , ... 17 (30%) : Acidaminococcus , Actinomyces , Anaerostipes , Enterobacteriaceae , Escherichia coli , Haemophilus , Klebsiella , ... 57 (100%) : Acidaminococcus , Actinomyces , Adlercreutzia , Alistipes , Anaerostipes , Bacteroides , Cellulomonas , ... 15 (26%) : Acidaminococcus , Alistipes , Bacteroides , Eisenbergiella , Enterobacteriaceae , Faecalibacterium , Klebsiella , ...
c33c
Alt-R CRISPR-Cas12a (Cpf1) genome editing
Alt-R A.s. Cas12a (Cpf1) Ultra and V3 nucleases are high purity, recombinant Acidaminococcus sp. Cas12a. The enzymes include ... Cas12a endonucleases from Acidaminococcus sp. BV3L6 or Lachnospiracaea bacterium ND2006 along with a crRNA is capable of ... a HEK-293-Cas12a cell line that stably expresses Acidaminococcus sp. Cas12a. Genomic DNA was isolated, and genome editing was ...
Model Search | BioModels
Fermentans2
- Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans. (mpg.de)
- Mortality and thigh swelling were pronounced (greater than 75%) in case of Fusobacterium gonidiaformans and Propionibacterium acnes but less (less than 50%) in Acidaminococcus fermentans. (who.int)
Cpf12
- The AsCas12a protein (also called Cpf1) is derived from Acidaminococcus sp. (logancollinsblog.com)
- Specifically, they used quantitative kinetics to dissect the reaction steps of DNA targeting by Acidaminococcus sp Cas12a (also known as Cpf1). (new21.net)
Genus1
- They also identified one class (Kiritimatiellae), one genus ( Acidaminococcus ), and one species ( Paraprevotella xylaniphila ) that are related to poor functional outcome 3 months after ischemic stroke. (medscape.com)
Related to poor functional1
- Negativibacillus and Lentisphaeria were associated with a more severe stroke in the acute phase (at 6 and 24 hours respectively) and Acidaminococcus related to poor functional outcomes at three months. (microbiota-site.com)
Status1
- CONCLUSIONS: Association of Acidaminococcus with gestational weight gain could reinforce the relevance with mothers' nutritional status for gut colonization at the beginning of life. (bvsalud.org)
Intestini1
- Acidaminococcus intestini is the first Negativicute bacterium (Gram‐negative Firmicute) shown to be resistant to beta‐lactam antibiotics. (usda.gov)