TartratesAcid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Laboratories: Facilities equipped to carry out investigative procedures.Diagnostic Techniques and Procedures: Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.Osteoclasts: A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.Menu PlanningPlasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Laboratory Animal Science: The science and technology dealing with the procurement, breeding, care, health, and selection of animals used in biomedical research and testing.Bone Resorption: Bone loss due to osteoclastic activity.Abbreviations as Topic: Shortened forms of written words or phrases used for brevity.Hexestrol: A synthetic estrogen that has been used as a hormonal antineoplastic agent.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Prostate: A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.TartratesProtein Tyrosine Phosphatases: An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.Thymolphthalein: Used as a pH indicator and as a reagent for blood after decolorizing the alkaline solution by boiling with zinc dust.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Prostatic Neoplasms: Tumors or cancer of the PROSTATE.Phosphoprotein Phosphatases: A group of enzymes removing the SERINE- or THREONINE-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase. (Enzyme Nomenclature, 1992)Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Bromcresol Purple: An indicator and reagent. It has been used for several purposes including the determination of serum albumin concentrationsTartratesPhosphoprotein Phosphatases: A group of enzymes removing the SERINE- or THREONINE-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase. (Enzyme Nomenclature, 1992)Protein Tyrosine Phosphatases: An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.Alkaline Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.Enzyme Assays: Methods used to measure the relative activity of a specific enzyme or its concentration in solution. Typically an enzyme substrate is added to a buffer solution containing enzyme and the rate of conversion of substrate to product is measured under controlled conditions. Many classical enzymatic assay methods involve the use of synthetic colorimetric substrates and measuring the reaction rates using a spectrophotometer.Reagent Kits, Diagnostic: Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.Lysosomes: A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture is supposed to be under metabolic (hormonal) control. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)Protein Phosphatase 2: A phosphoprotein phosphatase subtype that is comprised of a catalytic subunit and two different regulatory subunits. At least two genes encode isoforms of the protein phosphatase catalytic subunit, while several isoforms of regulatory subunits exist due to the presence of multiple genes and the alternative splicing of their mRNAs. Protein phosphatase 2 acts on a broad variety of cellular proteins and may play a role as a regulator of intracellular signaling processes.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Prostate: A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.TartratesThymolphthalein: Used as a pH indicator and as a reagent for blood after decolorizing the alkaline solution by boiling with zinc dust.Protein Tyrosine Phosphatases: An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.Prostatic Neoplasms: Tumors or cancer of the PROSTATE.Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.Semen: The thick, yellowish-white, viscid fluid secretion of male reproductive organs discharged upon ejaculation. In addition to reproductive organ secretions, it contains SPERMATOZOA and their nutrient plasma.Prostatic Diseases: Pathological processes involving the PROSTATE or its component tissues.Phenolphthaleins: A family of 3,3-bis(p-hydroxyphenyl)phthalides. They are used as CATHARTICS, indicators, and COLORING AGENTS.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Phosphoprotein Phosphatases: A group of enzymes removing the SERINE- or THREONINE-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase. (Enzyme Nomenclature, 1992)TartratesProtein Tyrosine Phosphatases: An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.Protein Phosphatase 2: A phosphoprotein phosphatase subtype that is comprised of a catalytic subunit and two different regulatory subunits. At least two genes encode isoforms of the protein phosphatase catalytic subunit, while several isoforms of regulatory subunits exist due to the presence of multiple genes and the alternative splicing of their mRNAs. Protein phosphatase 2 acts on a broad variety of cellular proteins and may play a role as a regulator of intracellular signaling processes.Protein Phosphatase 1: A eukayrotic protein serine-threonine phosphatase subtype that dephosphorylates a wide variety of cellular proteins. The enzyme is comprised of a catalytic subunit and regulatory subunit. Several isoforms of the protein phosphatase catalytic subunit exist due to the presence of multiple genes and the alternative splicing of their mRNAs. A large number of proteins have been shown to act as regulatory subunits for this enzyme. Many of the regulatory subunits have additional cellular functions.Kinetics: The rate dynamics in chemical or physical systems.Phosphoric Monoester Hydrolases: A group of hydrolases which catalyze the hydrolysis of monophosphoric esters with the production of one mole of orthophosphate. EC 3.1.3.Glucose-6-Phosphatase: An enzyme that catalyzes the conversion of D-glucose 6-phosphate and water to D-glucose and orthophosphate. EC 3.1.3.9.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Sequence Analysis, Protein: A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Dictionaries, MedicalAcid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Dictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Phosphoprotein Phosphatases: A group of enzymes removing the SERINE- or THREONINE-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase. (Enzyme Nomenclature, 1992)TartratesProtein Tyrosine Phosphatases: An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.Dictionaries, ChemicalProtein Phosphatase 2: A phosphoprotein phosphatase subtype that is comprised of a catalytic subunit and two different regulatory subunits. At least two genes encode isoforms of the protein phosphatase catalytic subunit, while several isoforms of regulatory subunits exist due to the presence of multiple genes and the alternative splicing of their mRNAs. Protein phosphatase 2 acts on a broad variety of cellular proteins and may play a role as a regulator of intracellular signaling processes.Protein Phosphatase 1: A eukayrotic protein serine-threonine phosphatase subtype that dephosphorylates a wide variety of cellular proteins. The enzyme is comprised of a catalytic subunit and regulatory subunit. Several isoforms of the protein phosphatase catalytic subunit exist due to the presence of multiple genes and the alternative splicing of their mRNAs. A large number of proteins have been shown to act as regulatory subunits for this enzyme. Many of the regulatory subunits have additional cellular functions.Terminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Histocytochemistry: Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.Lymphocytes: White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.Phytohemagglutinins: Mucoproteins isolated from the kidney bean (Phaseolus vulgaris); some of them are mitogenic to lymphocytes, others agglutinate all or certain types of erythrocytes or lymphocytes. They are used mainly in the study of immune mechanisms and in cell culture.TartratesMitosis: A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species.Cytoplasmic Granules: Condensed areas of cellular material that may be bounded by a membrane.Lymphocyte Activation: Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.Lectins: Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.Lysosomes: A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture is supposed to be under metabolic (hormonal) control. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)Ciliophora: A phylum of EUKARYOTES characterized by the presence of cilia at some time during the life cycle. It comprises three classes: KINETOFRAGMINOPHOREA; OLIGOHYMENOPHOREA; and POLYMENOPHOREA.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Vacuoles: Any spaces or cavities within a cell. They may function in digestion, storage, secretion, or excretion.Osteoclasts: A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.RANK Ligand: A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.Bone Resorption: Bone loss due to osteoclastic activity.Pinocytosis: The engulfing of liquids by cells by a process of invagination and closure of the cell membrane to form fluid-filled vacuoles.Microscopy, Electron: Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.Receptor Activator of Nuclear Factor-kappa B: A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.Latex: A milky, product excreted from the latex canals of a variety of plant species that contain cauotchouc. Latex is composed of 25-35% caoutchouc, 60-75% water, 2% protein, 2% resin, 1.5% sugar & 1% ash. RUBBER is made by the removal of water from latex.(From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed). Hevein proteins are responsible for LATEX HYPERSENSITIVITY. Latexes are used as inert vehicles to carry antibodies or antigens in LATEX FIXATION TESTS.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.TartratesOsteoclasts: A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.Bone Resorption: Bone loss due to osteoclastic activity.RANK Ligand: A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.Isoenzymes: Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.Antimony Potassium Tartrate: A schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Phosphoprotein Phosphatases: A group of enzymes removing the SERINE- or THREONINE-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase. (Enzyme Nomenclature, 1992)Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.Prostate: A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.TartratesProtein Tyrosine Phosphatases: An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.Thymolphthalein: Used as a pH indicator and as a reagent for blood after decolorizing the alkaline solution by boiling with zinc dust.Prostatic Neoplasms: Tumors or cancer of the PROSTATE.Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.Semen: The thick, yellowish-white, viscid fluid secretion of male reproductive organs discharged upon ejaculation. In addition to reproductive organ secretions, it contains SPERMATOZOA and their nutrient plasma.Prostatic Diseases: Pathological processes involving the PROSTATE or its component tissues.Phenolphthaleins: A family of 3,3-bis(p-hydroxyphenyl)phthalides. They are used as CATHARTICS, indicators, and COLORING AGENTS.
(1/2302) Enzymes and reproduction in natural populations of Drosophila euronotus.

Populations of Drosophila euronotus, one from southern Louisiana )3 samples), and one from Missouri (2 samples), were classified for allele frequencies at alkaline phosphatase (APH) and acid phosphatase (ACPH) loci. The two populations differed consistently in allele frequencies at both loci. The APH locus is on the inversion-free X chromosome; the chromosomal locus of the autosomal ACPH is unknown, and could involve inversion polymorphism. Wild females from Missouri and Louisiana populations heterozygous at the APH locus carried more sperm at capture than did the corresponding homozygotes. This heterotic association was significant for the combined samples, and whether it was the result of heterosis at the enzyme locus studied, or due to geographically widespread close linkage with other heterotic loci, it should help to maintain heterozygosity at the APH locus. In a Louisiana collection which included large numbers of sperm-free females, simultaneous homozygosity at both enzyme loci was significantly associated with lack of sperm. It is suggested that the latter association is the result of young heterozygous females achieving sexual maturity earlier than do the double homozygotes. The average effective sperm load for 225 wild females was only 29.4, suggesting the necessity for frequent repeat-mating in nature to maintain female fertility. A comparison of the sex-linked APH genotypes of wild females with those of their daughters indicated that among 295 wild-inseminated females from five populations, 35% had mated more than once, and of this 35%, six females had mated at least three times. Because of ascertainment difficulties, it is clear that the true frequency of multiple-mating in nature must have been much higher than the observed 35%. Laboratory studies indicate that multiple-mating in this species does not involve sperm displacement, possibly due to the small number of sperms transmitted per mating, and the fact that the sperm receptacles are only partially filled by a given mating.  (+info)

(2/2302) Endometrial lysosomal enzyme activity in normal cycling endometrium.

The objective of this study was to evaluate the possible role of four lysosomal enzymes in endometrial function and remodelling during the normal menstrual cycle by fluorimetric measurement (acid phosphatase, N-acetyl-beta-D-glucosaminidase, alpha-L-fucosidase and alpha-D-mannosidase). A prospective study was conducted of 45 endometrial biopsies obtained from women with normal menstrual cycles. Activity of all four enzymes was identified in human endometrium. Activity of acid phosphatase and N-acetyl-beta-D-glucosaminidase was relatively high, whilst that of alpha-L-fucosidase and alpha-D-mannosidase was low. There was no significant change in the activity of any of the four enzymes from the proliferative to the secretory phase of the cycle. This study suggests that the activity of these enzymes remains constant throughout a major portion of the normal cycle.  (+info)

(3/2302) Strong induction of members of the chitinase family of proteins in atherosclerosis: chitotriosidase and human cartilage gp-39 expressed in lesion macrophages.

Atherosclerosis is initiated by the infiltration of monocytes into the subendothelial space of the vessel wall and subsequent lipid accumulation of the activated macrophages. The molecular mechanisms involved in the anomalous behavior of macrophages in atherogenesis have only partially been disclosed. Chitotriosidase and human cartilage gp-39 (HC gp-39) are members of the chitinase family of proteins and are expressed in lipid-laden macrophages accumulated in various organs during Gaucher disease. In addition, as shown in this study, chitotriosidase and HC gp-39 can be induced with distinct kinetics in cultured macrophages. We investigated the expression of these chitinase-like genes in the human atherosclerotic vessel wall by in situ hybridizations on atherosclerotic specimens derived from femoral artery (4 specimens), aorta (4 specimens), iliac artery (3 specimens), carotid artery (4 specimens), and coronary artery (1 specimen), as well as 5 specimens derived from apparently normal vascular tissue. We show for the first time that chitotriosidase and HC gp-39 expression was strongly upregulated in distinct subsets of macrophages in the atherosclerotic plaque. The expression patterns of chitotriosidase and HC gp-39 were compared and shown to be different from the patterns observed for the extracellular matrix protein osteopontin and the macrophage marker tartrate-resistant acid phosphatase. Our data emphasize the remarkable phenotypic variation among macrophages present in the atherosclerotic lesion. Furthermore, chitotriosidase enzyme activity was shown to be elevated up to 55-fold in extracts of atherosclerotic tissue. Although a function for chitotriosidase and HC gp-39 has not been identified, we hypothesize a role in cell migration and tissue remodeling during atherogenesis.  (+info)

(4/2302) An activation-specific role for transcription factor TFIIB in vivo.

A yeast mutant was isolated encoding a single amino acid substitution [serine-53 --> proline (S53P)] in transcription factor TFIIB that impairs activation of the PHO5 gene in response to phosphate starvation. This effect is activation-specific because S53P did not affect the uninduced level of PHO5 expression, yet is not specific to PHO5 because Adr1-mediated activation of the ADH2 gene also was impaired by S53P. Pho4, the principal activator of PHO5, directly interacted with TFIIB in vitro, and this interaction was impaired by the S53P replacement. Furthermore, Pho4 induced a conformational change in TFIIB, detected by enhanced sensitivity to V8 protease. The S53P replacement also impaired activation of a lexA(op)-lacZ reporter by a LexA fusion protein to the activation domain of Adr1, thereby indicating that the transcriptional effect on ADH2 expression is specific to the activation function of Adr1. These results define an activation-specific role for TFIIB in vivo and suggest that certain activators induce a conformational change in TFIIB as part of their mechanism of transcriptional stimulation.  (+info)

(5/2302) A study of the genetical structure of the Cuban population: red cell and serum biochemical markers.

Gene frequencies of several red cell and serum gentic markers were determined in the three main racial groups--whites, mulattoes and Negroes--of the Cuban population. The results were used to estimate the relative contribution of Caucasian and Negro genes to the genetic makeup of these three groups and to calculate the frequencies of these genes in the general Cuban population.  (+info)

(6/2302) An in vitro system recapitulates chromatin remodeling at the PHO5 promoter.

The Saccharomyces cerevisiae gene PHO5 is an excellent system with which to study regulated changes in chromatin structure. The PHO5 promoter is packaged into four positioned nucleosomes under repressing conditions; upon induction, the structure of these nucleosomes is altered such that the promoter DNA becomes accessible to nucleases. We report here the development and characterization of an in vitro system in which partially purified PHO5 minichromosomes undergo promoter chromatin remodeling. Several hallmarks of the PHO5 chromatin transition in vivo were reproduced in this system. Chromatin remodeling of PHO5 minichromosomes required the transcription factors Pho4 and Pho2, was localized to the promoter region of PHO5, and was independent of the chromatin-remodeling complex Swi-Snf. In vitro chromatin remodeling also required the addition of fractionated nuclear extract and hydrolyzable ATP. This in vitro system should serve as a useful tool for identifying the components required for this reaction and for elucidating the mechanism by which the PHO5 promoter chromatin structure is changed.  (+info)

(7/2302) Laser induced phagocytosis in the pigment epithelium of the Hunter dystrophic rat.

The retinae of 14-day-old Hunter dystrophic rats have been subjected to low-energy irradiation by a pulsed ruby laser. Fifteen days after exposure, pigment epithelial cells had proliferated and repopulated the irradiated areas. In all such areas the subretinal photoreceptor debris had been reduced or lost.  (+info)

(8/2302) The active site of purple acid phosphatase from sweet potatoes (Ipomoea batatas) metal content and spectroscopic characterization.

Purple acid phosphatase from sweet potatoes Ipomoea batatas (spPAP) has been purified to homogeneity and characterized using spectroscopic investigations. Matrix-assisted laser desorption/ionization mass spectrometry analysis revealed a molecular mass of approximately 112 kDa. The metal content was determined by X-ray fluorescence using synchrotron radiation. In contrast to previous studies it is shown that spPAP contains a Fe(III)-Zn(II) center in the active site as previously determined for the purple acid phosphatase from red kidney bean (kbPAP). Moreover, an alignment of the amino acid sequences suggests that the residues involved in metal-binding are identical in both plant PAPs. Tyrosine functions as one of the ligands for the chromophoric Fe(III). Low temperature EPR spectra of spPAP show a signal near g = 4.3, characteristic for high-spin Fe(III) in a rhombic environment. The Tyr-Fe(III) charge transfer transition and the EPR signal are both very sensitive to changes in pH. The pH dependency strongly suggests the presence of an ionizable group with a pKa of 4.7, arising from an aquo ligand coordinated to Fe(III). EPR and UV/visible studies of spPAP in the presence of the inhibitors phosphate or arsenate suggest that both anions bind to Fe(III) in the binuclear center replacing the coordinated water or hydroxide ligand necessary for hydrolysis. The conserved histidine residues of spPAP corresponding to His202 and His296 in kbPAP probably interact in catalysis.  (+info)

*  Osteoclast
This permits characterization of osteoclasts by their staining for high expression of tartrate resistant acid phosphatase (TRAP ... These vacuoles include lysosomes filled with acid phosphatase. ... Energy-dependent acid transport was verified and the postulated ... Attachment to the bone matrix is facilitated by integrin receptors, such as αvβ3, via the specific amino acid motif Arg-Gly-Asp ... The osteoclast disassembles and digests the composite of hydrated protein and mineral at a molecular level by secreting acid ...
*  Acid phosphatase
Testicular acid phosphatase Tissue acid phosphatase, or Lysosomal acid phosphatase Alkaline phosphatase Henneberry, M.O.; Engel ... is Acid-Phosphatase negative , T-ALL ( originating instead from T Lymphocytes ) is acid-phosphatase positive . Acid phosphatase ... Acid phosphatase (EC 3.1.3.2, acid phosphomonoesterase, phosphomonoesterase, glycerophosphatase, acid monophosphatase, acid ... Minkin, Cedrick (1982). "Bone Acid Phosphatase: Tartrate-resistant Acid Phosphatase as a Marker of Osteoclast Function". ...
*  Prostatic acid phosphatase
... (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. It ... "Prostatic acid phosphatase in serum of patients with prostatic cancer is a specific phosphotyrosine acid phosphatase". Clin. ... "Human prostatic acid phosphatase: cDNA cloning, gene mapping and protein sequence homology with lysosomal acid phosphatase". ... "Nucleotide sequence of human prostatic acid phosphatase determined from a full-length cDNA clone". Nucleic Acids Res. 18 (16): ...
*  Phosphatidic acid phosphatase 2c
PPAP2C phosphatidic acid phosphatase type 2C". Nanjundan M, Possmayer F (2003). "Pulmonary phosphatidic acid phosphatase and ... The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid ... Hooks SB, Ragan SP, Lynch KR (Jun 1998). "Identification of a novel human phosphatidic acid phosphatase type 2 isoform". FEBS ... This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 ...
*  Tartrate-resistant acid phosphatase
... (TRAP or TRAPase), also called acid phosphatase 5, tartrate resistant (ACP5), is a ... Minkin C (1982). "Bone acid phosphatase: tartrate-resistant acid phosphatase as a marker of osteoclast function". Calcif. ... tartrate-resistant acid phosphatase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... Klabunde T, Sträter N, Fröhlich R, Witzel H, Krebs B (1996). "Mechanism of Fe(III)-Zn(II) purple acid phosphatase based on ...
*  Purple acid phosphatases
... (PAPs) (EC 3.1.3.2) are metalloenzymes that hydrolyse phosphate esters and anhydrides under acidic ... PAPs are highly conserved within eukaryotic species, with >80% amino acid homology in mammalian PAPs, and >70% sequence ...
*  Lysophosphatidic acid phosphatase type 6
Acid phosphatase Prostatic acid phosphatase Lysophosphatidic acid Lipid metabolism Tartrate-resistant acid phosphatase Alkaline ... Lysophosphatidic acid phosphatase type 6 is an acid phosphatase enzyme that is encoded in humans by the ACP6 gene. It acts as a ... Lysophosphatidic acid phosphatase is also responsible for the digestion of lysophosphatidic acids when the cell enters a state ... Phosphatidic acids can also be hydrolyzed by lysophosphatidic acid phosphatase, but at a significantly lower rate. The addition ...
*  Glycerol-2-phosphatase
Tsuboi KK, Wiener G, Hudson PB (1957). "Acid phosphatase. VII. Yeast phosphomonoesterase; isolation procedure and stability ... In enzymology, a glycerol-2-phosphatase (EC 3.1.3.19) is an enzyme that catalyzes the chemical reaction glycerol 2-phosphate + ... Other names in common use include beta-glycerophosphatase, beta-glycerophosphate phosphatase, and 2-glycerophosphatase. Boyer, ...
*  List of OMIM disorder codes
SLC7A7 Lysosomal acid phosphatase deficiency; 200950; ACP2 Lysyl hydroxylase 3 deficiency; 612394; PLOD3 Machado-Joseph disease ... FREM1 Bile acid malabsorption, primary; 613291; SLC10A2 Bile acid synthesis defect, congenital, 2; 235555; AKR1D1 Bile acid ... SBDS Sialic acid storage disorder, infantile; 269920; SLC17A5 Sialidosis, type I; 256550; NEU1 Sialidosis, type II; 256550; ... DLAT Pyruvate dehydrogenase phosphatase deficiency; 608782; PDP1 Pyruvate kinase deficiency; 266200; PKLR Rabson-Mendenhall ...
*  Dendreon
In the case of Provenge, this disease related protein is prostatic acid phosphatase and the signalling component is GM-CSF. ... October 2008). "Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine". Neuron. 60 (1 ... Disclosed are a novel prostatic acid phosphatase and corresponding coding region derived from mouse. Also disclosed is a method ... Erbas H, Erten O, Irfanoglu ME (December 2007). "Prostatic acid phosphatase in breast cyst fluid". The Malaysian Journal of ...
*  Parathyroid chief cell
These granules can contain acid phosphatase. Acid phosphatase is only found in larger secretory granules, 400 to 900 nm in ... This acid phosphatase is also present in the Golgi apparatus of the chief cell. However, the Golgi apparatus areas associated ... Chief cells in parathyroid adenomas also display acid phosphatase activity. It is a benign tumor of the gland that requires ... Shannon, W. Allen; Roth, Sanford I. (1974-12-01). "An Ultrastructural Study of Acid Phosphatase Activity in Normal, Adenomatous ...
*  Nucleoside-triphosphatase
Brightwell R, Tappel AL (1968). "Lysosomal acid pyrophosphatase and acid phosphatase". Arch. Biochem. Biophys. 124 (1): 333-43 ... This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing ...
*  Exonuclease III
Richardson CC, Lehman IR, Kornberg A (January 1964). "A Deoxyribonucleic Acid Phosphatase-Exonuclease from Escherichia coli. II ... Linxweiler W, Hörz W (August 1982). "Sequence specificity of exonuclease III from E. coli". Nucleic Acids Res. 10 (16): 4845-59 ... phosphatase and AP-endonuclease activities. Temperature, salt concentration and the ratio of enzyme to DNA greatly affect ...
*  PPAP2B
"Entrez Gene: PPAP2B phosphatidic acid phosphatase type 2B". "PLPP3 - Phospholipid phosphatase 3 - Homo sapiens (Human) - PLPP3 ... Lipid phosphate phosphohydrolase 3 (LPP3), also known as phospholipid phosphatase 3 (PLPP3) and phosphatidic acid phosphatase ... Ishikawa T, Kai M, Wada I, Kanoh H (April 2000). "Cell surface activities of the human type 2b phosphatidic acid phosphatase". ... Ishikawa T, Kai M, Wada I, Kanoh H (April 2000). "Cell surface activities of the human type 2b phosphatidic acid phosphatase". ...
*  ACP2
Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. Lysosomal acid phosphatase is composed of ... and is chemically and genetically distinct from red cell acid phosphatase. Lysosomal acid phosphatase 2 is a member of a family ... Radzun HJ, Parwaresch MR (1981). "Isoelectric focusing pattern of acid phosphatase and acid esterase in human blood cells, ... "Entrez Gene: ACP2 acid phosphatase 2, lysosomal". Human ACP2 genome location and ACP2 gene details page in the UCSC Genome ...
*  Dullard protein
Dullard dephosphorylates the mammalian phospatidic acid phosphatase, lipid. Dullard participates in a unique phosphatase ... which include phosphatase activity and protein serine/threonine phosphatase activity. This gene is relatively small and only ... Dullard is a member of DXDX(T/V) phosphatase family. It was shown in 2002 to be a potential regulator of neural tube ... contains 244 amino acids. Dullard protein or CTDnep1 encodes a protein serine/threonine phosphatase and dephosphoroylates LPIN1 ...
*  Exodeoxyribonuclease III
Richardson, C.C.; Lehman, I.R.; Kornberg, A. (1964). "A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. II ... Richardson, C.C.; Kornberg, A. (1964). "A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. I. Purification ... of the enzyme and characterization of the phosphatase activity". J. Biol. Chem. 239: 242-250. PMID 14114850. ...
*  Janet Sawicki
Yasbin, R; Sawicki, J; MacIntyre, RJ (1978). "A developmental study of acid phosphatase-1 in Drosophila melanogaster". Dev Biol ... Sawicki, J; MacIntyre, RJ (1977). "Synthesis of ovarian acid phosphatase in Drosophila melanogaster". Dev Biol. 60 (1): 1-13. ... level of maternally derived enzyme and determination of the time of paternal gene expression for acid phosphatase-1 in ...
*  PPAP2A
Lipid phosphate phosphohydrolase 1 also known as phosphatidic acid phosphatase 2a is an enzyme that in humans is encoded by the ... Ulrix W, Swinnen JV, Heyns W, Verhoeven G (1998). "Identification of the phosphatidic acid phosphatase type 2a isozyme as an ... "Entrez Gene: PPAP2A phosphatidic acid phosphatase type 2A". Kanoh H, Kai M, Wada I (1999). "Molecular characterization of the ... Hooks SB, Ragan SP, Lynch KR (1998). "Identification of a novel human phosphatidic acid phosphatase type 2 isoform". FEBS Lett ...
*  Phosphoglycolate phosphatase
Richardson, K. E.; Tolbert, N. E. (1961-05-01). "Phosphoglycolic Acid Phosphatase". Journal of Biological Chemistry. 236 (5): ... 2-phosphoglycolate phosphatase, P-glycolate phosphatase, and phosphoglycollate phosphatase, is an enzyme responsible for ... a feature consistent with other acid phosphatases. In addition, electrostatic surface analysis indicates a relatively acidic ... In the presence of 0.02 mM phosphoglycolate, the phosphatase activity of 2,3-DPG is activated more than 1000-fold. The ...
*  Leishmania donovani
Here they secrete promastigote secretory gel (PSG), which is composed of soluble acid phosphatase and phosphoglycoprotein. ... Bates, PA; Dwyer, DM (1987). "Biosynthesis and secretion of acid phosphatase by Leishmania donovani promastigotes". Molecular ...
*  PPAPDC1A
Phosphatidate phosphatase PPAPDC1A also known as phosphatidic acid phosphatase type 2 domain containing 1A is an enzyme that in ... phosphatidic acid phosphatase type 2 domain containing 1A". Takeuchi M, Harigai M, Momohara S, Ball E, Abe J, Furuichi K, ... PPAPDC1A has phosphatidate phosphatase activity. GRCh38: Ensembl release 89: ENSG00000203805 - Ensembl, May 2017 GRCm38: ... representatives of a novel type of mammalian phosphatidate phosphatase". Gene. 399 (2): 174-80. doi:10.1016/j.gene.2007.05.009 ...
*  Macrococcus brunensis
Alkaline and acid phosphatases are produced, nitrates are reduced. Acetoin, clumping factor and coagulase are not produced and ... Acid is produced from D-fructose, D-glucose, maltose, D-mannitol and D-trehalose. Acid is not produced from arabinose, N- ... Predominant fatty acids are iso-13 : 0, iso-15 : 0, anteiso-15:0, 16:1-omega-11c, iso-17:1-omega-10c and 18:1-omega-9c. This ...
*  List of most-produced firearms
Wan, H.; Horvath, C. (1975-11-20). "Behavior of soluble and immobilized acid phosphatase in hydro-organic media". Biochimica et ...
*  Dog
Acid phosphatase, handy enzyme that separates the dog from the wolf. Acta Biologica et Medica Germanica 28:957-62 Mech, D. L. ( ... Domesticated dogs are clearly distinguishable from wolves by starch gel electrophoresis of red blood cell acid phosphatase. The ...
*  Prokaryotic DNA replication
Nucleic Acids Research. 42 (21): 13134-49. doi:10.1093/nar/gku1051. PMC 4245941 . PMID 25378325. Ishida T, Akimitsu N, Kashioka ... by inorganic phosphatase) into two phosphates. This hydrolysis drives DNA synthesis to completion. Furthermore, DNA polymerase ...
Tartrate Resistant Acid Phosphatase Test, Risk Factors of TRAP Test, Procedure.  Tartrate Resistant Acid Phosphatase Test, Risk Factors of TRAP Test, Procedure.
... side effects of tartrate resistant acid phosphatase test and more. ... Tartrate resistant acid phosphatase test, treatment, preventions, precautions, risk factors, procedure, results, complications ... Tartrate Resistant Acid Phosphatase Test is a comprehensive medical test which aims at measuring the level of acid phosphatase ... This test is also known as Type 5b acid phosphatase test.. Purpose of theTest. Your physician may suggest you to go for the ...
more infohttp://www.altiusdirectory.com/Health/tartrate-resistant-acid-phosphatase-test.php
Human Prostatic Acid Phosphatase/ACPP ELISA Kit (Colorimetric) (KA1911): Novus Biologicals  Human Prostatic Acid Phosphatase/ACPP ELISA Kit (Colorimetric) (KA1911): Novus Biologicals
High sensitivity ELISA kit for detection of Prostatic Acid Phosphatase/ACPP. Backed by our 100% Guarantee. ... Human Prostatic Acid Phosphatase/ACPP ELISA Kit (Colorimetric). ... Prostatic Acid Phosphatase/ACPP ELISA Kit. * Prostatic Acid ... Additional Prostatic Acid Phosphatase/ACPP Products. Prostatic Acid Phosphatase/ACPP KA1911 * Prostatic Acid Phosphatase/ACPP ... Home » Prostatic Acid Phosphatase/ACPP » Prostatic Acid Phosphatase/ACPP ELISA Kits » Human Prostatic Acid Phosphatase/ACPP ...
more infohttps://www.novusbio.com/products/prostatic-acid-phosphatase-acpp-elisa-kit_ka1911
Comparison of enzyme-linked immunosorbent assay and radioimmunoassay for prostate-specific acid phosphatase in prostatic...  Comparison of enzyme-linked immunosorbent assay and radioimmunoassay for prostate-specific acid phosphatase in prostatic...
Although prostate-specific acid phosphatase is not a cancer-specific enzyme, we conclude that its measurement may be of ... Comparison of enzyme-linked immunosorbent assay and radioimmunoassay for prostate-specific acid phosphatase in prostatic ... Comparison of enzyme-linked immunosorbent assay and radioimmunoassay for prostate-specific acid phosphatase in prostatic ... Comparison of enzyme-linked immunosorbent assay and radioimmunoassay for prostate-specific acid phosphatase in prostatic ...
more infohttp://clinchem.aaccjnls.org/content/28/1/183.long
Inhibition of osteoclast differentiation and bone resorption by N-methylpyrrolidone  - Zurich Open Repository and Archive  Inhibition of osteoclast differentiation and bone resorption by N-methylpyrrolidone - Zurich Open Repository and Archive
NMP inhibited RANKL-induced tartrate-resistant acid phosphatase activity and the formation of tartrate-resistant acid ... NMP inhibited RANKL-induced tartrate-resistant acid phosphatase activity and the formation of tartrate-resistant acid ... phosphatase-positive multinucleated cells. The RANKL-induced expression of NFATc1 (nuclear factor of activated T cells, ... phosphatase-positive multinucleated cells. The RANKL-induced expression of NFATc1 (nuclear factor of activated T cells, ...
more infohttp://www.zora.uzh.ch/id/eprint/52664/
Pleckstrin Homology Domain Leucine-Rich Repeat Protein Phosphatases Se by Gloria Reyes, Matt Niederst et al.  "Pleckstrin Homology Domain Leucine-Rich Repeat Protein Phosphatases Se" by Gloria Reyes, Matt Niederst et al.
Here we show that the pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP) suppresses receptor tyrosine ... unidentified epigenetic mechanism unrelated to its previously described function as the hydrophobic motif phosphatase for the ... Here we show that the pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP) suppresses receptor tyrosine ... Pleckstrin Homology Domain Leucine-Rich Repeat Protein Phosphatases Set the Amplitude of Receptor Tyrosine Kinase Output ...
more infohttps://uknowledge.uky.edu/biochem_facpub/64/
Acid Phosphatase, Tartrate Resistant  Acid Phosphatase, Tartrate Resistant
... ,ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative ... Acid Phosphatase, Prostatic. 2. Acid Phosphatase, Total, Serum. 3. Alkaline Phosphatase, Bone Specific. 4. Alkaline Phosphatase ... Tartrate Resistant Acid Phosphatase Stain. 6. Chemically Resistant Sealing Mat for 384-well Plate. 7. Chemically Resistant ...
more infohttp://www.bio-medicine.org/medicine-products/Acid-Phosphatase--Tartrate-Resistant-20917-1/
Prostatic Acid Phosphatase - Medical Dictionary / Glossary | Medindia  Prostatic Acid Phosphatase - Medical Dictionary / Glossary | Medindia
Prostatic Acid Phosphatase' - PAP. An enzyme produced by the prostate. It may be found in increased amounts in men who have ... Medical Word - Prostatic Acid Phosphatase. Ans : PAP. An enzyme produced by the prostate. It may be found in increased amounts ... Prostatic Acid Phosphatase - Glossary. Written & Compiled by Medindia Content Team. Medically Reviewed by The Medindia Medical ...
more infohttps://www.medindia.net/glossary/prostatic_acid_phosphatase.htm
Anti-Prostatic Acid Phosphatase antibody (ab97517)  Anti-Prostatic Acid Phosphatase antibody (ab97517)
Rabbit polyclonal Prostatic Acid Phosphatase antibody validated for WB and tested in Human. Referenced in 1 publication. ... Anti-Prostatic Acid Phosphatase antibody. See all Prostatic Acid Phosphatase primary antibodies. ... Recombinant protein fragment corresponding to a region within amino acids 177 and 372 of Human Prostatic Acid Phosphatase ( ... Anti-Prostatic Acid Phosphatase antibody (ab97517) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg. Predicted band size : ...
more infohttp://www.abcam.com/prostatic-acid-phosphatase-antibody-ab97517.html
Acid Phosphatase Assay Kit (ab83367) | Abcam  Acid Phosphatase Assay Kit (ab83367) | Abcam
Assay Acid phosphatase activity in 1 hr 10 min in cell culture media, cell/tissue extracts, and biofluids with ab83367. For ... Acid phosphatases (AP) dephosphorylate phosphate groups from phosphate esters under acid conditions. Different acid phosphatase ... Acid phosphatases (AP) dephosphorylate phosphate groups from phosphate esters under acid conditions. Different acid phosphatase ... as a phosphatase substrate. They can be used to measure alkaline phosphatase, neutral phosphatase, and acid phosphatase ...
more infohttps://www.abcam.com/acid-phosphatase-assay-kit-colorimetric-ab83367.html
Arabidopsis thaliana mRNA for acid phosphatase-like protein, complete  - Nucleotide - NCBI  Arabidopsis thaliana mRNA for acid phosphatase-like protein, complete - Nucleotide - NCBI
Arabidopsis thaliana mRNA for acid phosphatase-like protein, complete cds, clone... Arabidopsis thaliana mRNA for acid ... Arabidopsis thaliana mRNA for acid phosphatase-like protein, complete cds, clone: RAFL14-33-N06. GenBank: AK227764.1 ... phosphatase-like protein, complete cds, clone: RAFL14-33-N06. gi,110743823,dbj,AK227764.1, ...
more infohttps://www.ncbi.nlm.nih.gov/nuccore?cmd=Retrieve&db=nucleotide&dopt=GenBank&list_uids=110743823
PLOS ONE: Monomeric Tartrate Resistant Acid Phosphatase Induces Insulin Sensitive Obesity  PLOS ONE: Monomeric Tartrate Resistant Acid Phosphatase Induces Insulin Sensitive Obesity
Tartrate resistant acid phosphatase (TRAP) is an enzyme expressed by subsets of macrophages and osteoclasts that exists either ...
more infohttp://journals.plos.org/plosone/article/email?id=10.1371/journal.pone.0001713
Prostatic Acid Phosphatase/ACPP Research Products: Novus Biologicals  Prostatic Acid Phosphatase/ACPP Research Products: Novus Biologicals
Browse our Prostatic Acid Phosphatase/ACPP product catalog backed by our Guarantee+. ... Prostatic Acid Phosphatase/ACPP products available through Novus Biologicals. ... PTMs for Prostatic Acid Phosphatase/ACPP. Learn more about PTMs related to Prostatic Acid Phosphatase/ACPP.. Cleavage. ... Diseases related to Prostatic Acid Phosphatase/ACPP. Discover more about diseases related to Prostatic Acid Phosphatase/ACPP.. ...
more infohttps://www.novusbio.com/common-name/prostatic-acid-phosphatase-acpp
ddephosphorylating proteins using acid phosphatase - General Lab Techniques  ddephosphorylating proteins using acid phosphatase - General Lab Techniques
ddephosphorylating proteins using acid phosphatase - (May/27/2008 ). Hi everybody,. I am going to use potato acid phosphatase ...
more infohttp://www.protocol-online.org/biology-forums/posts/36747.html
RCSB PDB - Protein Feature View 









 - Purple acid phosphatase 1 - Q9SE00 (PPAF1 IPOBA)  RCSB PDB - Protein Feature View - Purple acid phosphatase 1 - Q9SE00 (PPAF1 IPOBA)
... nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to ... See also Velankar et al., Nucleic Acids Research 33, D262-265 (2005). ...
more infohttp://www.rcsb.org/pdb/protein/Q9SE00
Innovative Prostatic Acid Phosphatase Testing Technologies and Emerging Markets  Innovative Prostatic Acid Phosphatase Testing Technologies and Emerging Markets
... Date:. November 27, 2012 ... Global Prostatic Acid Phosphatase Testing Market: Forecasts and Supplier Shares 2010-2015 (DataPack) US$ 2,320.00 Jul, 2012 ... A. Prostatic Acid Phosphatase: Clinical Significance and Laboratory Practices. B. Instrumentation Review And Market Needs. 1. ... PROSTATIC ACID PHOSPHATASE: US, EUROPE, JAPAN. Test Volume, Sales Forecasts by Supplier Shares. ...
more infohttps://marketpublishers.com/report/life_sciences/diagnostics-diseases/innovative-prostatic-acid-phosphatase-testing-technologies-n-emerging-markets.html
Acpp - Prostatic acid phosphatase precursor - Rattus norvegicus (Rat) - Acpp gene & protein  Acpp - Prostatic acid phosphatase precursor - Rattus norvegicus (Rat) - Acpp gene & protein
Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (By similarity). ... A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) ... Prostatic acid phosphataseAdd BLAST. 350. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical ... "Site-directed mutagenesis of prostatic acid phosphatase. Catalytically important aspartic acid 258, substrate specificity, and ...
more infohttps://www.uniprot.org/uniprot/P20646
Acid phosphatase | definition of acid phosphatase by Medical dictionary  Acid phosphatase | definition of acid phosphatase by Medical dictionary
... acid phosphatase explanation free. What is acid phosphatase? Meaning of acid phosphatase medical term. What does acid ... Looking for online definition of acid phosphatase in the Medical Dictionary? ... Related to acid phosphatase: acid phosphatase stain, Acid Phosphatase Test acid. [as´id] 1. sour. ... alkaline phosphatase see alkaline phosphatase.. ac·id phos·pha·tase. a phosphatase with an optimum pH of less than 7 (for ...
more infohttps://medical-dictionary.thefreedictionary.com/acid+phosphatase
Bone acid phosphatase: Tartrate-resistant acid phosphatase as a marker of osteoclast function | SpringerLink  Bone acid phosphatase: Tartrate-resistant acid phosphatase as a marker of osteoclast function | SpringerLink
Organ cultures of newborn mouse calvaria were used to test the hypothesis that tartrate-resistant acid phosphatase might serve ... Bone acid phosphatase: Tartrate-resistant acid phosphatase as a marker of osteoclast function. ... in vitro results in the release of tartrate-resistant acid phosphatase from osteoclasts and tartrate-sensitive acid phosphatase ... Yam, L. T.: Clinical significance of the human acid phosphatases. A review, Am. J. Med.56:604-616, 1974CrossRefPubMedGoogle ...
more infohttps://link.springer.com/article/10.1007/BF02411252
HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphatase | SpringerLink  HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphatase | SpringerLink
Prostatic acid phosphatase (PAP) has been investigated as the target of several antigen-specific anti-prostate tumor vaccines. ... CTL Prostatic acid phosphatase (PAP) HLA-A2 ELISPOT Epitope This is a preview of subscription content, log in to check access. ... Prostatic acid phosphatase (PAP) has been investigated as the target of several antigen-specific anti-prostate tumor vaccines. ... Wang Y, Harada M, Yano H, Ogasawara S, Takedatsu H, Arima Y, Matsueda S, Yamada A, Itoh K (2005) Prostatic acid phosphatase as ...
more infohttps://link.springer.com/article/10.1007%2Fs00262-010-0820-6
Acid Phosphatase-Rich Granules in Human Lymphocytes Induced by Phytohemagglutinin | Science  Acid Phosphatase-Rich Granules in Human Lymphocytes Induced by Phytohemagglutinin | Science
Acid Phosphatase-Rich Granules in Human Lymphocytes Induced by Phytohemagglutinin Message Subject. (Your Name) has forwarded a ... Acid Phosphatase-Rich Granules in Human Lymphocytes Induced by Phytohemagglutinin. By Rochelle Hirschhorn, J. Martin Kaplan, ... Acid Phosphatase-Rich Granules in Human Lymphocytes Induced by Phytohemagglutinin. By Rochelle Hirschhorn, J. Martin Kaplan, ... It is possible that enzymes present in granules which stain for acid phosphatase activity (lysosome-like) may play a role in ...
more infohttp://science.sciencemag.org/content/147/3653/55
  • Besides substrates such as β -glycerophosphate, lysophosphatidic acid, and phosphoamino acids, PAP can also catalyze AMP [ 16 ] and, in fact, PAP-mediated adenosine formation has been shown to be an important regulator of pain by inhibiting nociceptive neurotransmission [ 17 - 19 ]. (hindawi.com)
  • 11 nonamer peptides derived from the amino acid sequence of PAP were used as stimulator antigens in functional ELISPOT assays with peripheral blood mononuclear cells from 20 HLA-A2+ patients with prostate cancer or ten healthy blood donors. (springer.com)
  • During formation of the food vacuole, the vacuolar membrane is acid phosphatase-negative. (rupress.org)
  • At about 20 min after formation, acid phosphatase-positive secondary pinocytotic vesicles pinch off from the food vacuoles and approach a separate system of membrane-bounded spaces. (rupress.org)
  • By 1 hr after formation, the food vacuole becomes acid phosphatase-negative, and the undigested latex particles are voided into the membrane-bounded spaces. (rupress.org)
  • The membrane-bounded spaces are closely associated with the food vacuole at all stages of digestion and are generally acid phosphatase-negative. (rupress.org)
  • Histochemical examination of these cells demonstrates that innumerable granules containing acid phosphatase develop in the cytoplasm before mitosis. (sciencemag.org)