The type species of gram negative, aerobic bacteria in the genus ACHROMOBACTER. Previously in the genus ALCALIGENES, the classification and nomenclature of this species has been frequently emended. The two subspecies, Achromobacter xylosoxidans subsp. denitrificans and Achromobacter xylosoxidans subsp. xylosoxidans are associated with infections.
Gram-Negative Bacterial Infections
Sequence Analysis, Protein
A method of differentiating individuals based on the analysis of qualitative or quantitative biological traits or patterns. This process which has applications in forensics and identity theft prevention includes DNA profiles or DNA fingerprints, hand fingerprints, automated facial recognition, iris scan, hand geometry, retinal scan, vascular patterns, automated voice pattern recognition, and ultrasound of fingers.
Radio Frequency Identification Device
Doping in Sports
RNA, Ribosomal, 16S
Sequence Analysis, DNA
Bacterial Typing Techniques
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
A species of gram-negative bacteria in the genus PSEUDOMONAS, containing multiple genomovars. It is distinguishable from other pseudomonad species by its ability to use MALTOSE and STARCH as sole carbon and energy sources. It can degrade ENVIRONMENTAL POLLUTANTS and has been used as a model organism to study denitrification.
A bacterial protein from Pseudomonas, Bordetella, or Alcaligenes which operates as an electron transfer unit associated with the cytochrome chain. The protein has a molecular weight of approximately 16,000, contains a single copper atom, is intensively blue, and has a fluorescence emission band centered at 308nm.
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.
Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
Bibliography as Topic
Discussion of lists of works, documents or other publications, usually with some relationship between them, e.g., by a given author, on a given subject, or published in a given place, and differing from a catalog in that its contents are restricted to holdings of a single collection, library, or group of libraries. (from The ALA Glossary of Library and Information Science, 1983)
Bibliography of Medicine
A process of preserving animal hides by chemical treatment (using vegetable tannins, metallic sulfates, and sulfurized phenol compounds, or syntans) to make them immune to bacterial attack, and subsequent treatments with fats and greases to make them pliable. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Escherichia coli O157
A verocytotoxin-producing serogroup belonging to the O subfamily of Escherichia coli which has been shown to cause severe food-borne disease. A strain from this serogroup, serotype H7, which produces SHIGA TOXINS, has been linked to human disease outbreaks resulting from contamination of foods by E. coli O157 from bovine origin.
omega-Amino acid:pyruvate transaminase from Alcaligenes denitrificans Y2k-2: a new catalyst for kinetic resolution of beta-amino acids and amines. (1/44)Alcaligenes denitrificans Y2k-2 was obtained by selective enrichment followed by screening from soil samples, which showed omega-amino acid:pyruvate transaminase activity, to kinetically resolve aliphatic beta-amino acid, and the corresponding structural gene (aptA) was cloned. The gene was functionally expressed in Escherichia coli BL21 by using an isopropyl-beta-D-thiogalactopyranoside (IPTG)-inducible pET expression system (9.6 U/mg), and the recombinant AptA was purified to show a specific activity of 77.2 U/mg for L-beta-amino-n-butyric acid (L-beta-ABA). The enzyme converts various beta-amino acids and amines to the corresponding beta-keto acids and ketones by using pyruvate as an amine acceptor. The apparent K(m) and V(max) for L-beta-ABA were 56 mM and 500 U/mg, respectively, in the presence of 10 mM pyruvate. In the presence of 10 mM L-beta-ABA, the apparent K(m) and V(max) for pyruvate were 11 mM and 370 U/mg, respectively. The enzyme exhibits high stereoselectivity (E > 80) in the kinetic resolution of 50 mM D,L-beta-ABA, producing optically pure D-beta-ABA (99% enantiomeric excess) with 53% conversion. (+info)
Pacemaker lead endocarditis caused by Achromobacter xylosoxidans. (2/44)We report the case of a 35-yr-old patient who presented with high fever and chills. He had undergone a patch closure of the ventricular septal defect 18 yr before. One year later, a VVI pacemaker was implanted via the right subclavian vein because of complete heart block. Nine years after that, a new VVI pacemaker with another right ventricular electrode was inserted controlaterally and the old pacing lead was abandoned. Trans-thoracic and trans-esophageal echocardiogram identified the pacemaker lead in the right ventricle (RV) attaching hyperechoic materials and also a fluttering round hyperechoic mass with a stalk in the RV outflow tract. Cultures in blood and pus from pacemaker lead grew Achromobacter xylosoxidans. A diagnosis of pacemaker lead endocarditis due to Achromobacter xylosoxidans was made. In this regards, the best treatment is an immediate removal of the entire pacing system and antimicrobial therapy. (+info)
Cloning, overexpression, and characterization of a novel thermostable penicillin G acylase from Achromobacter xylosoxidans: probing the molecular basis for its high thermostability. (3/44)The gene encoding a novel penicillin G acylase (PGA), designated pgaW, was cloned from Achromobacter xylosoxidans and overexpressed in Escherichia coli. The pgaW gene contains an open reading frame of 2586 nucleotides. The deduced protein sequence encoded by pgaW has about 50% amino acid identity to several well-characterized PGAs, including those of Providencia rettgeri, Kluyvera cryocrescens, and Escherichia coli. Biochemical studies showed that the optimal temperature for this novel PGA (PGA650) activity is greater than 60 degrees C and its half-life of inactivation at 55 degrees C is four times longer than that of another previously reported thermostable PGA from Alcaligenes faecalis (R. M. D. Verhaert, A. M. Riemens, J. V. R. Laan, J. V. Duin, and W. J. Quax, Appl. Environ. Microbiol. 63:3412-3418, 1997). To our knowledge, this is the most thermostable PGA ever characterized. To explore the molecular basis of the higher thermostability of PGA650, homology structural modeling and amino acid composition analyses were performed. The results suggested that the increased number of buried ion pair networks, lower N and Q contents, excessive arginine residues, and remarkably high content of proline residues in the structure of PGA650 could contribute to its high thermostability. The unique characteristic of higher thermostability of this novel PGA provides some advantages for its potential application in industry. (+info)
Structure-based engineering of Alcaligenes xylosoxidans copper-containing nitrite reductase enhances intermolecular electron transfer reaction with pseudoazurin. (4/44)The intermolecular electron transfer from Achromobacter cycloclastes pseudoazurin (AcPAZ) to wild-type and mutant Alcaligenes xylosoxidans nitrite reductases (AxNIRs) was investigated using steady-state kinetics and electrochemical methods. The affinity and the electron transfer reaction constant (k(ET)) are considerably lower between AcPAZ and AxNIR (K(m) = 1.34 mM and k(ET) = 0.87 x 10(5) M(-1) s(-1)) than between AcPAZ and its cognate nitrite reductase (AcNIR) (K(m) = 20 microM and k(ET) = 7.3 x 10(5) M(-1) s(-1)). A negatively charged hydrophobic patch, comprising seven acidic residues around the type 1 copper site in AcNIR, is the site of protein-protein interaction with a positively charged hydrophobic patch on AcPAZ. In AxNIR, four of the negatively charged residues (Glu-112, Glu-133, Glu-195, and Asp-199) are conserved at the corresponding positions of AcNIR, whereas the other three residues are not acidic amino acids but neutral amino acids (Ala-83, Ala-191, and Gly-198). Seven mutant AxNIRs with additional negatively charged residues surrounding the hydrophobic patch of AxNIR (A83D, A191E, G198E, A83D/A191E, A93D/G198E, A191E/G198E, and A83D/A191E/G198E) were prepared to enhance the specificity of the electron transport reaction between AcPAZ and AxNIR. The k(ET) values of these mutants become progressively larger as the number of mutated residues increases. The K(m) and k(ET) values of A83D/A191E/G198E (K(m) = 88 microM and k(ET) = 4.1 x 10(5) M(-1) s(-1)) are 15-fold smaller and 4.7-fold larger than those of wild-type AxNIR, respectively. These results suggest that the introduction of negatively charged residues into the docking surface of AxNIR facilitates both the formation of electron transport complex and the electron transfer reaction. (+info)
The completely sequenced plasmid pEST4011 contains a novel IncP1 backbone and a catabolic transposon harboring tfd genes for 2,4-dichlorophenoxyacetic acid degradation. (5/44)The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D)-degrading bacterium Achromobacter xylosoxidans subsp. denitrificans strain EST4002 contains plasmid pEST4011. This plasmid ensures its host a stable 2,4-D(+) phenotype. We determined the complete 76,958-bp nucleotide sequence of pEST4011. This plasmid is a deletion and duplication derivative of pD2M4, the 95-kb highly unstable laboratory ancestor of pEST4011, and was self-generated during different laboratory manipulations performed to increase the stability of the 2,4-D(+) phenotype of the original strain, strain D2M4(pD2M4). The 47,935-bp catabolic region of pEST4011 forms a transposon-like structure with identical copies of the hybrid insertion element IS1071::IS1471 at the two ends. The catabolic regions of pEST4011 and pJP4, the best-studied 2,4-D-degradative plasmid, both contain homologous, tfd-like genes for complete 2,4-D degradation, but they have little sequence similarity other than that. The backbone genes of pEST4011 are most similar to the corresponding genes of broad-host-range self-transmissible IncP1 plasmids. The backbones of the other three IncP1 catabolic plasmids that have been sequenced (the 2,4-D-degradative plasmid pJP4, the haloacetate-catabolic plasmid pUO1, and the atrazine-catabolic plasmid pADP-1) are nearly identical to the backbone of R751, the archetype plasmid of the IncP1 beta subgroup. We show that despite the overall similarity in plasmid organization, the pEST4011 backbone is sufficiently different (51 to 86% amino acid sequence identity between individual backbone genes) from the backbones of members of the three IncP1 subgroups (the alpha, beta, and gamma subgroups) that it belongs to a new IncP1subgroup, the delta subgroup. This conclusion was also supported by a phylogenetic analysis of the trfA2, korA, and traG gene products of different IncP1 plasmids. (+info)
Pitfalls of polymyxin antimicrobial susceptibility testing of Pseudomonas aeruginosa isolated from cystic fibrosis patients. (6/44)OBJECTIVES AND METHODS: With their potent activity against Gram-negative bacteria, the polymyxins are important alternative antibiotics for cystic fibrosis (CF) patients. A retrospective evaluation of polymyxin activity against 6001 Pseudomonas aeruginosa, 150 Achromobacter xylosoxidans and 506 Stenotrophomonas maltophilia CF isolates was initiated. In addition, we looked at how polymyxin susceptibility testing was affected by the testing method (agar dilution versus microdilution), the agent (polymyxin E versus polymyxin B), incubation time (24 h versus 48 h) and by different interpretative criteria (German DIN, French FSM, British BSAC). RESULTS: Polymyxin B exhibited reasonable activity against P. aeruginosa (MIC(90)< or =2 mg/L), whereas it was less active against A. xylosoxidans (MIC(90)< or =16 mg/L) and S. maltophilia (MIC(90)< or =16 mg/L). During 2000-2002, polymyxin B resistance in P. aeruginosa, S. maltophilia and A. xylosoxidans was found to be 6.7%, 17.0% and 29.9% (corresponding to 12.4%, 20.7% and 35.4% of infected patients), respectively. When the agar dilution method was used, polymyxin E exhibited higher MICs than polymyxin B. The microdilution method produced lower polymyxin MICs than the agar dilution method. Therefore, the microdilution MICs after prolonged incubation (48 h) and the agar dilution MICs of polymyxin B correlated best (AUC of 0.93, r(2) of 0.44 and s of 0.83). CONCLUSIONS: Polymyxin resistance among common CF pathogens is not rare, thus underlining the necessity of accurate susceptibility testing. When compared with the agar dilution method, it was found that the microdilution method is a valid, rapid and cost effective alternative for the determination of polymyxin activity. The performance of the microdilution method was most reliable after prolonged incubation (48 h) at a susceptibility breakpoint of < or =4 mg/L according to the BSAC guidelines (specificity 91%, sensitivity 89%, 1.5% very major errors). (+info)
Cyclo(L-leucyl-L-prolyl) produced by Achromobacter xylosoxidans inhibits aflatoxin production by Aspergillus parasiticus. (7/44)Aflatoxins are potent carcinogenic and toxic substances that are produced primarily by Aspergillus flavus and Aspergillus parasiticus. We found that a bacterium remarkably inhibited production of norsolorinic acid, a precursor of aflatoxin, by A. parasiticus. This bacterium was identified as Achromobacter xylosoxidans based on its 16S ribosomal DNA sequence and was designated A. xylosoxidans NFRI-A1. A. xylosoxidans strains commonly showed similar inhibition. The inhibitory substance(s) was excreted into the medium and was stable after heat, acid, or alkaline treatment. Although the bacterium appeared to produce several inhibitory substances, we finally succeeded in purifying a major inhibitory substance from the culture medium using Diaion HP20 column chromatography, thin-layer chromatography, and high-performance liquid chromatography. The purified inhibitory substance was identified as cyclo(L-leucyl-L-prolyl) based on physicochemical methods. The 50% inhibitory concentration for aflatoxin production by A. parasiticus SYS-4 (= NRRL2999) was 0.20 mg ml(-1), as determined by the tip culture method. High concentrations (more than 6.0 mg ml(-1)) of cyclo(L-leucyl-L-prolyl) further inhibited fungal growth. Similar inhibitory activities were observed with cyclo(D-leucyl-D-prolyl) and cyclo(L-valyl-L-prolyl), whereas cyclo(D-prolyl-L-leucyl) and cyclo(L-prolyl-D-leucyl) showed weaker activities. Reverse transcription-PCR analyses showed that cyclo(L-leucyl-L-prolyl) repressed transcription of the aflatoxin-related genes aflR, hexB, pksL1, and dmtA. This is the first report of a cyclodipeptide that affects aflatoxin production. (+info)
Shared genotypes of Achromobacter xylosoxidans strains isolated from patients at a cystic fibrosis rehabilitation center. (8/44)During a study examining transmission of Pseudomonas aeruginosa among 76 cystic fibrosis patients in a rehabilitation center, where patients stay in close contact during prolonged periods, several clusters of patients carrying genotypically identical P. aeruginosa, as well as two clusters of 4 and 10 patients, respectively, colonized with genotypically identical Achromobacter xylosoxidans strains, were discovered. (+info)
Achromobacter xylosoxidans | definition of Achromobacter xylosoxidans by Medical dictionary
Looking for online definition of Achromobacter xylosoxidans in the Medical Dictionary? Achromobacter xylosoxidans explanation free. What is Achromobacter xylosoxidans? Meaning of Achromobacter xylosoxidans medical term. What does Achromobacter xylosoxidans mean?
Shared Genotypes of Achromobacter xylosoxidans Strains Isolate...
Shared Genotypes of Achromobacter xylosoxidans Strains Isolated from Patients at a Cystic Fibrosis Rehabilitation Center: During a study examining transmission
Achromobacter xylosoxidans - Wikipedia
Achromobacter xylosoxidans (formerly Alcaligenes xylosoxidans) is a Gram-negative, aerobic, oxidase and catalase-positive, motile bacterium with peritrichous flagella, from the genus Achromobacter. It is generally found in wet environments. Achromobacter xylosoxidans can cause infections such as bacteremia, especially in patients with cystic fibrosis. In 2013, the complete genome of an A. xylosoxidans strain from a patient with cystic fibrosis was sequenced. A. xylosoxidans is a Gram-negative rod that does not form spores. It is motile, with peritrichous flagella that distinguish it from Pseudomonas species, and is oxidase-positive, catalase-positive, and citrate-positive. It is urease and indole-negative. It produces acid oxidatively from xylose, but not from lactose, maltose, mannitol, or sucrose. It grows well on MacConkey agar and other inhibitory growth media such as deoxycholate, Salmonella-Shigella, and nalidixic acid-cetrimide agars. It is usually resistant to a variety of antibiotics ...
Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas...
TY - JOUR. T1 - Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa. AU - Mima, Takehiko. AU - Kohira, Naoki. AU - Li, Yang. AU - Sekiya, Hiroshi. AU - Ogawa, Wakano. AU - Kuroda, Teruo. AU - Tsuchiya, Tomofusa. PY - 2009. Y1 - 2009. N2 - muxA-muxB-muxC-opmB (formerly PA2528-PA2527-PA2526-opmB), encoding a putative resistance nodulation cell division (RND)-type multidrug efflux pump system, was cloned from Pseudomonas aeruginosa PAO1. Introduction of muxABC-opmB into P. aeruginosa YM64, a drug-hypersusceptible strain, led to elevated MICs of aztreonam, macrolides, novobiocin and tetracycline. Since muxB and muxC, both of which encode RND components, were essential for function, MuxABC-OpmB is thought to be a drug efflux pump with four components. One novobiocin-resistant mutant, PMX725, isolated from P. aeruginosa PMX7 showed elevated resistance not only to novobiocin but also to aztreonam, macrolides and ...
Achromobacter xylosoxidans: a rare pathogen for community‐acquired acute pancreatitis | Microbiology Society
Introduction: Achromobacter xylosoxidans is a water‐borne organism that causes healthcare‐associated infections and has been isolated from blood, cerebrospinal fluid, stool, urine, sputum, peritoneal fluid, skin, ear discharge, wounds, abscesses, bone, joints, endocardium and central venous catheters, mostly in immunocompromised patients. Case presentation: We describe here the rare case of a young immunocompetent alcoholic male admitted with symptoms of acute pancreatitis who failed to improve with conventional management. Blood culture later showed the growth of A. xylosoxidans. The patient improved when he was treated with antibiotics as per the sensitivity report. Conclusion: Although Achromobacter is rarely isolated from clinical samples, it should never be assumed to be a contaminant as this infection has propensity for progression to fatal bacteraemia, even in apparently healthy individuals.
Biotic inactivation of the Pseudomonas aeruginosa quinolone signal molecule - Nottingham ePrints
In Pseudomonas aeruginosa, quorum sensing (QS) regulates the production of secondary metabolites, many of which are antimicrobials that impact on polymicrobial community composition. Consequently, quenching QS modulates the environmental impact of P. aeruginosa. To identify bacteria capable of inactivating the QS signal molecule 2-heptyl-3- hydroxy-4(1H)-quinolone (PQS), a minimal medium containing PQS as the sole carbon source was used to enrich a Malaysian rainforest soil sample. This yielded an Achromobacter xylosoxidans strain (Q19) that inactivated PQS, yielding a new fluorescent compound (I-PQS) confirmed as PQS-derived using deuterated PQS. The I-PQS structure was elucidated using mass spectrometry and nuclear magnetic resonance spectroscopy as 2-heptyl-2-hydroxy-1,2-dihydroquinoline- 3,4-dione (HHQD). Achromobacter xylosoxidans Q19 oxidized PQS congeners with alkyl chains ranging from C1 to C5 and also N-methyl PQS, yielding the corresponding 2-hydroxy-1,2-dihydroquinoline-3,4- diones, ...
Alcaligenes xylosoxidans Bloodstream Infections in Outpatient Oncology Office - Volume 14, Number 7-July 2008 - Emerging...
This large outbreak (N = 12) of A. xylosoxidans bloodstream infections was caused by 1 strain, which was also isolated from CVC biofilm. Symptoms of bloodstream infection probably occurred when flushes detached bacteria from the CVC biofilm. The prospective study found that 3 (10%) of 29 patients had A. xylosoxidans-positive blood cultures. Our case-control and prospective studies support the association of A. xylosoxidans bloodstream infection and CVCs, and our molecular biologic studies confirm A. xylosoxidans biofilm of the same outbreak strain on a CVC. A. xylosoxidans outbreaks reported to date have been associated with healthcare and contamination of hospital products (1,2,5,12-14), but none occurred in an outpatient setting.. The cause of this outbreak most likely was the use of contaminated multidose vials of heparin or saline flushes, leading to the formation of an A. xylosoxidans biofilm on CVCs. Case-patient 1 had been hospitalized from late October through early November at Hospital ...
Seasonality of acquisition of respiratory bacterial pathogens in young children with cystic fibrosis | BMC Infectious Diseases ...
Seasonal variations are often observed for respiratory tract infections; however, limited information is available regarding seasonal patterns of acquisition of common cystic fibrosis (CF)-related respiratory pathogens. We previously reported differential seasonal acquisition of Pseudomonas aeruginosa in young children with CF and no such variation for methicillin-susceptible Staphylococcus aureus acquisition. The purpose of this study was to describe and compare the seasonal incidence of acquisition of other respiratory bacterial pathogens in young children with CF. We conducted a retrospective study to describe and compare the seasonal incidence of methicillin-resistant Staphylococcus aureus (MRSA), Stenotrophomonas maltophilia, Achromobacter xylosoxidans, and Haemophilus influenzae acquisition in young CF patients residing in the U.S. using the Cystic Fibrosis Foundation National Patient Registry, 2003-2009. Log-linear overdispersed Poisson regression was used to evaluate seasonal acquisition of each
Table - Amoebae-resisting Bacteria Isolated from Human Nasal Swabs by Amoebal Coculture - Volume 10, Number 3-March 2004 -...
Amoebae feed on bacteria, and few bacteria can resist their microbicidal ability. Amoebal coculture could therefore be used to selectively grow these amoebae-resisting bacteria (ARB), which may be human pathogens. To isolate new ARB, we performed amoebal coculture from 444 nasal samples. We recovered 7 (1.6%) ARB from 444 nasal swabs, including 4 new species provisionally named Candidatus Roseomonas massiliae, C. Rhizobium massiliae, C. Chryseobacterium massiliae, and C. Amoebinatus massiliae. The remaining isolates were closely related to Methylobacterium extorquens, Bosea vestrii, and Achromobacter xylosoxidans. Thus, amoebal coculture allows the recovery of new bacterial species from heavily contaminated samples and might be a valuable approach for the recovery of as-yet unrecognized emerging pathogens from clinical specimens.
Gluconate dehydratase - Mitsui Chemicals, Inc.
A novel gluconate dehydratase derived from |i|Achromobacter xylosoxidans |/i|and a gene encoding the gluconate dehydratase are provided. By reacting the gluconate dehydratase or a transformed cell con
Uncovering Differences in Virulence Markers Associated with Achromobacter Species of CF and Non-CF Origin
Achromobacter spp. are recognized as emerging pathogens in hospitalized as well as in cystic fibrosis (CF) patients. From 2012 to 2015, we collected 69 clinical isolates (41 patient) of Achromobacter spp. from 13 patients with CF (CF isolates, n = 32) and 28 patients receiving care for other health conditions (non-CF isolates, n = 37). Molecular epidemiology and virulence potential of isolates were examined. Antimicrobial susceptibility, motility, ability to form biofilms and binding affinity to mucin, collagen, and fibronectin were tested to assess their virulence traits. The nrdA gene sequencing showed that A. xylosoxidans was the most prevalent species in both CF and non-CF patients. CF patients were also colonized with A. dolens/A, ruhlandii, A. insuavis, and A. spiritinus strains while non-CF group was somewhat less heterogenous, although A. insuavis, A. insolitus, and A. piechaudii strains were detected beside A. xylosoxidans. Three strains displayed clonal distribution, one amon...g ...
CiNii 論文 - Construction of a Leftover Bath Water Model for Microbial Testing ...
In this study, in order to construct a model of leftover bath water, we analyzed one hundred samples of used bath water samples which were provided by twenty-eight volunteer families. It appeared that the number of detected bacteria from such bath water was correlated closely with the number of bathers. Moreover, the pH, acidity, chemical oxygen demand (COD), ion, protein content of the leftover bath water were measured. The number of bathers had no connection with the pH, acidity, COD, and ion content of the leftover bath water. However, the protein content of the bath water correlated with the number of detected bacteria. Based on these results, the model of leftover bath water was constructed. ,I,Achromobacter xylosoxidans, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa,/I, were incubated with the model bath wateras indices of bath water contamination. The number of incubated viable cells in the model bath water increased ...
Fatal non-thrombotic pulmonary embolization in a patient with undiagnosed factitious disorder | BMC Research Notes | Full Text
Factitious fever is extremely challenging to diagnose in patients with complicated chronic medical problems, and represents as much as 10% of fevers of unknown origin. Factitious fever caused by self-injecting oral medications through indwelling central catheters is a diagnostic challenge. We present a 32-year-old Caucasian female with history of short gut syndrome, malnutrition requiring total parental nutrition, and pancreatic auto-islet transplant with fever of unknown origin. Multiple episodes of bacteremia occurred with atypical pathogens, including α-hemolytic Streptococcus, Achromobacter xylosoxidans, and Mycobacterium mucogenicum. Chest computed tomography was notable for extensive tree-in-bud infiltrates. Sudden cardiac arrest with right-sided heart failure following acute hypoxemia led to her death. Diffuse microcrystalline cellulose emboli with foreign body granulomatosis was found on autopsy. Circumstantial evidence indicated that this patient suffered from factitious disorder, and was self
Colonization by Alcaligenes xylosoxidans in children with cystic fibrosis: a retrospective clinical study conducted by means of...
Colonization by Alcaligenes xylosoxidans in children with cystic fibrosis: a retrospective clinical study conducted by means of molecular epidemiological investigation
The Ascending Aorta Pseudoaneurysm with Myocardium Rupture Complicated with Prosthetic Valve Infective Endocarditis after...
Atsushi Kobayashi, Kazuhiko Nakazato, Yuichiro Jin, Hiroyuki Yamauchi, Takashi Kaneshiro, Masayoshi Oikawa, Hitoshi Suzuki, Shu-ichi Saitoh and Yasuchika Takeishi-The Ascending Aorta Pseudoaneurysm with Myocardium Rupture Complicated with Prosthetic Valve Infective Endocarditis after Aortic Valve Replacement
RCSB PDB - 3ZTZ: Cytochrome c prime from alcaligenes xylosoxidans: carbon monooxide bound L16G variant at 1.05 A resolution:...
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
Black dots contaminant phenonmenon: helpful paper - Tissue and Cell Culture - BioForum
Black dots contaminant phenonmenon: helpful paper - posted in Tissue and Cell Culture: Dear all,It seems like many researcher faced with this bizarre black dancing dots in cell culture, and me too! So Ive search about this issue and found one paper that published in Biologicals 2010. Gray JS, Birmingham JM, Fenton JI.Got black swimming dots in your cell culture? Identification of Achromobacter as a novel cell culture contaminant Biologicals. 2010 Mar;38(2):273-7. Epub 2009 Nov 18....
Prevalence and Outcomes of Achromobacter Species Infections in Adults with Cystic Fibrosis: a North American Cohort Study |...
Achromobacter species derived from the sputa of CF patients are garnering increasing attention. Indeed, improvements in diagnostic techniques enabling the correct distinction of these species from other CF pathogens, such as P. aeruginosa, and selective antimicrobial pressures may have contributed to their initial recognition (19, 23), although their rates did not appear to be changing over the last decade (7). Our study is the first to report epidemiological and clinical outcome data for CF patients infected with Achromobacter species in a North American cohort.. The cumulative prevalence of Achromobacter isolation of 11% in our center is comparable to those previously reported for small centers, which ranged from 5 to 29% (11, 12), although this spans 3 decades, making the incidence of infection very low. While others have reported that older patients and patients with greater lung disease burden appear to be predisposed to infection with Achromobacter species (11, 18), we did not observe any ...
A Tn 5051 -like mer -containing transposon identified in a heavy metal tolerant strain Achromobacter sp. AO22 | BMC Research...
Achromobacter sp. AO22 (formerly Alcaligenes sp. AO22), a bacterial strain isolated from a lead-contaminated industrial site in Australia, was previously found to be resistant to moderate to high levels of mercury, copper and other heavy metals. However, the nature and location of the genetic basis for mercuric ion resistance in this strain, had not been previously identified. Achromobacter sp. AO22 contains a functional mer operon with all four essential genes (merRTPA) and shows |99% DNA sequence identity to that of Tn501. The mer operon was present on a transposon, designated TnAO22, captured by introducing a broad-host-range IncP plasmid into Achromobacter sp. AO22 and subsequently transferring it to E. coli recipients. The transposition frequency of TnAO22 was 10-2 to 10-3 per target plasmid transferred. Analysis of TnAO22 sequence revealed it belonged to the Tn21 subgroup of the Tn3 superfamily of transposons, with the transposition module having |99% identity with Tn5051 of a Pseudomonas putida
Preoperative use and safety of coronary angiography for acute aortic valve infective endocarditis | Heart
Background Preoperative coronary angiography (CA) is recommended in patients with acute aortic valve infective endocarditis (AV-IE) and high cardiovascular risk profile but the level of evidence is low and its potential interest may be counterbalanced by the risk of dislodgement of vegetations and contrast-induced nephropathy.. Objective To review the use, indications and complication of preoperative CA in patients with AV-IE.. Design Retrospective study.. Patients Consecutive series of 83 patients operated on for AV-IE between January 2002 and March 2007.. Results CA was performed in 36 (43%) patients, all but one as a preoperative test. Significant (≥70%) lesions were observed in 10 patients and six underwent an associated coronary artery bypass graft. 47 patients were operated on without preoperative CA because of young age in 16 or recent CA in 13. Despite being theoretically indicated in all but one of the 18 remaining patients, CA was not performed because surgery as judged too urgent ...
RCSB PDB - 1GS6: Crystal structure of M144A mutant of Alcaligenes xylosoxidans Nitrite Reductase Literature Report...
1GS6: Biochemical and Crystallographic Studies of the met144Ala, Asp92Asn and His254Phe Mutants of the Nitrite Reductase from Alcaligenes Xylosoxidans Provide Insight Into the Enzyme Mechanism.
Role of arginine residues of D-aminoacylase from Alcaligenes x...
Role of arginine residues of D-aminoacylase from Alcaligenes xylosoxydans subsp. xylosoxydans A-6.: To investigate the role of arginine in the folding of d-amin
Award Data | SBIR.gov
PROJECT SUMMARY Bacterial infections such as those of prosthetic joints, bones (osteomyelitis) and heart valves (infective endocarditis) are difficult to diagnose and treat, and are a major cause of mortality, morbidity and health care costs. The long-term goal of our program is to develop a positron emission tomography (PET) radiotracer that can be used for non-invasive PET imaging to detect and .... ...
Fermentation Processes - Patent application
0048]In a preferred embodiment the esterase is a lipolytic enzyme, more preferably, a lipase. As used herein, lipolytic enzymes refers to lipases and phospholipases (including lyso-phospholipases). The lipolytic enzyme is preferably of microbial origin, in particular of bacterial, fungal or yeast origin. The lipolytic enzyme used may be derived from any source, including, for example, a strain of Absidia, in particular Absidia blakesleena and Absidia corymbifera, a strain of Achromobacter, in particular Achromobacter iophagus, a strain of Aeromonas, a strain of Alternaria, in particular Alternaria brassiciola, a strain of Aspergillus, in particular Aspergillus niger and Aspergillus flavus, a strain of Achromobacter, in particular Achromobacter iophagus, a strain of Aureobasidium, in particular Aureobasidium puliulans, a strain of Bacillus, in particular Bacillus pumilus, Bacillus strearothermophilus and Bacillus subtilis, a strain of Beauveria, a strain of Brochothtix, in particular ...
中国科学院南海海洋研究所机构知识库(SCSIO OpenIR): Contribution to deterioration of polymeric materials by a slow-growing bacterium Nocardia...
Bacteria capable of degrading polymeric products were isolated from several sources including tap water, sediment, and a deteriorated polymeric product. Alcaligenes xylosoxidans; T2, Pseudomonas aeruginosa GP10, and Nocardia corynebacterioides S3 were able to utilize rubber products as a sole source of carbon and energy. These microorganisms showed different growth patterns in mineral salt media (MSM) supplemented with rubber strips or with the rubber extract. A. xylosoxidans T2, P. aeruginosa GP10 and N. corynebacterioides S3 reduced the weight of the rubber product by approximately 2.0, 4.0 and 5.3%, respectively, after 70 days of incubation with the rubber product in MSM. On average, 0.45 mg (water-soluble carbon) g(-1) of the rubber product was released into solution phase after 7 days of incubation. Growth of N. corynebacterloides S3 was initially slower but exceeded the other two bacteria upon colonization of the polymer products. N. corynebacterioides S3 formed a dense biofilm on surfaces ...
Prevalence and species distribution of Achromobacter sp. cultured from cystic fibrosis patients attending the Aarhus centre in...
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks available to our members so that they can generate new knowledge about microbes and ensure that it is shared with other communities.
Separation/Purification Archives - Page 5 of 7 - BioProcess InternationalBioProcess International | Page 5
The biopharmaceutical industry needs faster and more efficient development of new drugs and their market introduction as well as shorter process development times for both upstream and downstream operations. It has become more commonplace to use high-throughput development techniques to save time (1). Development is also sped up by applying platform technologies based on the unsurpassed selectivity of protein A resins (2,3,4,5,6), which is the foundation for downstream processing of monoclonal antibodies (MAbs). This is the second of two articles…. ...
Achromobacter spp. healthcare associated infections in the French West Indies: a longitudinal study from 2006 to 2016 | BMC...
Bacteria of the Achromobacter genus, more particularly xylosoxidans species, are responsible for various healthcare associated infections (HAI) which are increasingly described since the last decade. Cystic fibrosis (CF) patients are considered as potential reservoirs in hospitals. We performed a retrospective study to estimate the frequencies of Achromobacter spp. HAI among patients from French West Indies, to determine characteristics of infected patients and establish a possible link between CF and infections. All adults with at least one Achromobacter spp. positive sample and infection criteria in accordance with European official definitions of HAI, hospitalized in University Hospital of Martinique from 2006 to 2016 for more than 48 h, were included. Patient clinical features, immune status and underlying diseases were obtained from medical files. A list of CF patients was given by clinicians. Antibiotic-susceptibility profiles of the strains were determined using an automated method. Mean
Newer CF Bacteria Species Shows Antibiotic Resistance, Ability to Spread
Achromobacter bacteria seen in chronic CF lung infections showed patient-to-patient transmission and emerging antibiotic resistance in study.
PPT - Design of Enzyme Reactor PowerPoint Presentation - ID:209542
Design of Enzyme Reactor. Geoff Greer Joseph Gvildys Aaron McGregor April 2 nd , 2007. Enzyme Selection. Transpeptidation Trypsin or Achromobacter lyticus proteinase I Optimal enzyme conditions 4 o C and a pH of 7. Eli Lilly. Enzyme Immobilization. Benefits Slideshow 209542 by...
GIDEON What is new!
Therapy Drug-drug interactions displayed by pressing [f3] while in the list of drugs will now display details of each interaction. The listings for drug toxicity and interactions have been extensively updated and expanded Drugs added Levofloxacin Pharmacological profile Ampicillin-sulbactam, Cefotetan, Doxycycline, Meningococcal vaccine, Ofloxacin, Pyrimethamine / sulfadoxine Susceptibility database Eubacterium lentum Testing criteria Levofloxaxin Interactions database Atorvastatin, Colestipol, Insulin, Molindone, Pirenzepine, Zalcitabine Microbiology Note: A variety of fermentation and other reactions for gram-positive bacilli and non-fermentative gram-negative bacilli may require three or more days. The GIDEON data base allows for delayed positivity in such cases. Therefore, do not indicate a negative response for such organisms until at least three days have passed (see individual notes [F2] in the identification module). New taxa added Achromobacter group B, Achromobacter group E, ...
Degradation of chlorophenol mixtures in a fed-batch system by two soil bacteria
This parameter is a very useful tool that involves the degradation rate and the biomass growth, referred to the initial biomass instead of the actual biomass. Progressively, the biomass grows and the degradation rate increases. This parameter simultaneously takes both into account.. Results and discussion. The mixed culture constituted of Pseudomonas aeruginosa and Achromobacter marplatensis was able to simultaneously degrade the mixture of highly-substituted chlorophenols PCP, 2,3,5,6-TeCP and 2,4,6-TCP, as the only source of carbon and energy in batch and fed-batch systems. The initial experimental settings for the fed-batch assays at different feed flow rates (I, II, III) and the batch system control (B) is shown in Table 1. The initial biomass was similar in all cases but the initial CP concentrations were much higher in B than in the fed-batch assays when they were close to zero (Table I). The substrate to biomass yield coefficients based on total CP degradation are also shown in Table 1. ...
Identification and control of bacterial contaminants fromIlex dumosanodal segments culture in a temporal immersion bioreactor...
Endogenous bacterial contaminants isolated from infected cultures of Ilex dumosa nodal segments were identified as Stenotrophomonas maltophilia and Achromobacter sp. using 16S rDNA analysis. A range o
Spontaneous activity of first-order horizontal canal ne - pick rate top
The presence of sepsis syndrome has evolved as an independent predictor of poor outcome in patients with high-risk malignancies accompanied by Achromobacter bloodstream infections. FCE 24517-resistant sildenafil generic MCF-7 human breast cancer cell line: selection and characterization. This effect is time dependent and the specific activity of enzyme increases significantly in hormone treated insects.. Neuroprotective, anesthetic, and cardiovascular effects of the NMDA antagonist, CNS 5161A, in isoflurane-anesthetized lambs. The Mini-Mental State Examination was used to identify cognitive impairment. Type I CD36 deficiency associated sildenafil citrate with metabolic syndrome and vasospastic angina: a case report. Effect of free fatty acid concentration on the transport and utilization of other albumin-bound compounds: hydroxyphenylazobenzoic acid. We therefore developed a bioinformatic method for detecting such gene pairs using an integrated analysis of genomic copy number sildenafil 100mg ...
Cystic Fibrosis Patients - The Balancing Act
Join us as an American company dedicates itself to meeting the demands of Cystic Fibrosis patients by bringing a whole level of care to this the disease.
Cystic fibrosis patients surviving longer in Canada than US
Cystic fibrosis patients are living longer than ever, but new research shows Canadians have about a 10-year survival advantage over Americans with the same genetic disease
Cystic Fibrosis Patients Need More Salt
Cystic fibrosis patients need more salt than an average person. Get a chemists explanation in laymans terms on why. Basically, we sweat too much salt out.
Cystic fibrosis patients dating
Canadians with cystic fibrosis tend to survive longer than American patients - a lot longer, a new study has found. Dangers of cystic fibrosis patients dating.
Potential drug could ease impact of bacterial lung infections in cystic fibrosis patients, tests suggest | Docphin
Potential drug could ease impact of bacterial lung infections in cystic fibrosis patients, tests suggest | ScienceDaily - Health and Medicine News | 10/14/2014
Cystic fibrosis patients may breathe easier, thanks to bioengineered antimicrobials
By better understanding how antimicrobials bind and thereby get inactivated in the mucus of air passages, researchers at the University of Illinois may have found a way to help cystic fibrosis patients fight off deadly infections.
Financial Support Resources for Cystic Fibrosis Patients
The cost of care for cystic fibrosis patients is high, which is why there are many programs in place that help provide financial support.
Research could be life-prolonging for cystic fibrosis patients
Preventing lung infections in childhood could stop later life-threatening infections for people with cystic fibrosis (CF), according to the latest research carried out at Aston University.
Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients |...
JoVE publishes peer-reviewed scientific video protocols to accelerate biological, medical, chemical and physical research. Watch our scientific video articles.
Data to Be Presented at ERS Conference Highlights Potential for Denufosol to Benefit Cystic Fibrosis Patients on Minimal...
Sep 17, 2010 - Inspire Pharmaceuticals, Inc. (NASDAQ ISPH) announced today that data will be presented on denufosol tetrasodium, an investigational therapy for
Comment on Kalydeco to be made available to Cystic Fibrosis patients in Ireland
The decision was announced today by Minister James Reilly after an agreement was reached with the HSE and the manufacturers of the drug.
Highlighted article - September 2016 - Highlighted Articles - Elsevier
Neutrophils from F508del cystic fibrosis patients produce IL-17A and express IL-23 - dependent IL-17RC Patricia R. Taylor, Tracey L. Bonfield,...
Roundup Ready - GMO Education Network
In an effort to engineer plants to be resistant to glyphosate, scientists starting looking for glyphosate resistant EPSP in the 1980s. Several methods were employed including selection, directed evolution, site-directed mutagenesis, and microbial screens. It was difficult to obtain a suitable enzyme because typically the resistant enzymes had an undesirable decrease in catalytic activity. Eventually, naturally occurring glyphosate-tolerant microbes were identified including Agrobacterium sp. Strain CP4, Achromobacter sp. Strain LBAA, and Pseudomonas sp. Strain PG2982. The enzymes isolate from these maintained good catalyctic ativity while being resistant to glyphosate (Funke). Agrobacterium sp. Strain CP4 was obtained from a glyphosate rich waste area at a glyphosate production facility. There is substantial sequence variation between these resistant enzymes and those of plants or E. coli. Other versions resistant versions of EPSP have been identified in Streptococcus pneumonia and ...
Differences in the degradation of native collagen by two microbial collagenases | Biochemical Journal
The early stages of degradation of native collagen by two bacterial collagenases were studied by electron microscopy and by automatic Edman degradation. The purified collagenase from Clostridium histolyticum was shown to cleave native collagen at several sites, but not progressively from the N-terminus, as had been previously suggested. The homogeneous collagenase from Achromobacter iophagus cleaves native collagen preferentially at two sites corresponding to the interbands 33-34 and 41-42. The latter lies within the region cleaved by the eukaryotic collagenases. ...
NanoBio reports good results on cystic fibrosis studies | Crains Detroit Business
Ann Arbor-based NanoBio Corp. announced Thursday at a medical conference that it got encouraging data from preclinical studies that one of its products was able to kill highly drug-resistant forms of bacteria commonly found in cystic fibrosis patients. The results were presented at the annual North American Cystic Fibrosis Conference in Minneapolis. Cystic fibrosis patients are susceptible to respiratory failure after repeated bacterial infections of the lungs.
Nitrite reductase (NO-forming)
Denitrificans". Biochim. Biophys. Acta. 828 (2): 130-137. doi:10.1016/0167-4838(85)90048-2. Godden JW; Turley, S; Teller, DC; ... Adman, ET; Liu, MY; Payne, WJ; Legall, J (1991). "The 2.3 angstrom X-ray structure of nitrite reductase from Achromobacter ... and copper-containing nitrous oxide reductase from Thiobacillus denitrificans". Arch. Microbiol. 165 (1): 55-61. doi:10.1007/ ...
... and reclassification of Alcaligenes denitrificans Rüger and Tan 1983 as Achromobacter denitrificans comb. nov". Int J Syst Evol ...
List of MeSH codes (B03)
Achromobacter cycloclastes MeSH B03.440.400.425.117.024.120 - Achromobacter denitrificans MeSH B03.440.400.425.117.050 - ... Achromobacter cycloclastes MeSH B03.660.075.027.030.120 - Achromobacter denitrificans MeSH B03.660.075.027.050 - Alcaligenes ... Paracoccus denitrificans MeSH B03.660.050.750.600.600 - Paracoccus pantotrophus MeSH B03.660.050.750.700 - Rhodobacter MeSH ... Paracoccus denitrificans MeSH B03.440.400.425.600.690 - Paracoccus pantotrophus MeSH B03.440.400.425.622 - Pseudoalteromonas ...
"Achromobacter denitrificans". DSMZ Leibniz Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH. Coenye, T. (2003). " ... Achromobacter xylosoxidans (A. x. subsp. denitrificans). "Genus Alcaligenes". LPSN. List of prokaryotic names with standing in ... Alcaligenes denitrificans is a Gram-negative, oxidase- and catalase-positive, strictly aerobic, motile bacterium with ... Based on 16S rDNA sequence analysis and the low degree of DNA relatedness between other members of Achromobacter species, ...
... is a Gram-negative, oxidase- and catalase-positive, strictly aerobic, ubiquitous, motile bacterium ... Type strain of Achromobacter denitrificans at BacDive - the Bacterial Diversity Metadatabase v t e. ... lpsn.dsmz.de MetaCyc Achromobacter denitrificans renal abscess Alessio Sgrelli, Antonella Mencacci, Maurizio Fiorio, Cristina ... from the genus Achromobacter which was isolated from soil and can cause human infections. ...
Achromobacter denitrificans - Wikipedia
Achromobacter denitrificans is a Gram-negative, oxidase- and catalase-positive, strictly aerobic, ubiquitous, motile bacterium ... Type strain of Achromobacter denitrificans at BacDive - the Bacterial Diversity Metadatabase v t e. ... lpsn.dsmz.de MetaCyc Achromobacter denitrificans renal abscess Alessio Sgrelli, Antonella Mencacci, Maurizio Fiorio, Cristina ... from the genus Achromobacter which was isolated from soil and can cause human infections. ...
'Watch out! Pneumonia secondary to achromobacter denitrificans...
We report a case of pneumonia caused by a very rare organism, Achromobacter denitrificans which was treated successfully with ... Review of available literature has documentation of isolation of Achromobacter xylosoxidans from endotracheal aspirate culture ... but this is probably the first case of pneumonia due to A. denitrificans.. ...
Proteins matched: Biphenyl BphD (MF 01688) | InterPro | EMBL-EBI
LMG 3412 Strain Passport - StrainInfo
Achromobacter species-yyy. Achromobacter denitrificans. Achromobacter xylosoxidans subsp. denitrificans. Alcaligenes aquatilis ... Achromobacter sp. CCUG 3353 aromatic-amino-acid transferase (tyrB) gene, partial cds. CCUG 3353 ... Achromobacter sp. CCUG 3353 RNA polymerase beta-subunit (rpoB) gene, partial cds. CCUG 3353 ... Achromobacter sp. CCUG 3353 ATP synthase beta-subunit (atpD) gene, partial cds. CCUG 3353 ...
LMG 3414 Strain Passport - StrainInfo
Achromobacter xylosoxidans subsp. xylosoxidans. Achromobacter xylosoxidans. Alcaligenes aquatilis denitrificans. Achromobacter ... Achromobacter xylosoxidans strain LMG 3414 aromatic-amino-acid transferase (tyrB) gene, partial cds. LMG 3414 ... Achromobacter xylosoxidans strain LMG 3414 RNA polymerase beta-subunit (rpoB) gene, partial cds. LMG 3414 ... Achromobacter xylosoxidans strain LMG 3414 recombinase A (recA) gene, partial cds. LMG 3414 ...
RCSB PDB - 1A4A: AZURIN MUTANT WITH MET 121 REPLACED BY HIS, PH 6.5 CRYSTAL FORM, DATA COLLECTED AT 16 DEGREES CELSIUS
Diversity | Free Full-Text | Examination of a Culturable Microbial Population from the Gastrointestinal Tract of the Wood...
Alcaligenes denitrificans - Wikipedia
"Achromobacter denitrificans". DSMZ Leibniz Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH. Coenye, T. (2003). " ... Achromobacter xylosoxidans (A. x. subsp. denitrificans). "Genus Alcaligenes". LPSN. List of prokaryotic names with standing in ... Alcaligenes denitrificans is a Gram-negative, oxidase- and catalase-positive, strictly aerobic, motile bacterium with ... Based on 16S rDNA sequence analysis and the low degree of DNA relatedness between other members of Achromobacter species, ...
Pseudomonas stutzeri (Pseudomonas perfectomarina)
Patent US8017749 - Compositions and methods to treat cancer with cupredoxins and CpG rich DNA - Google Patents
SEQ ID NO: 7. Amino acid sequence of azurin from Achromobacter xylosoxidans ssp. denitrificans I. ... denitrificans I, Bordetella bronchiseptica, Methylomonas sp., Neisseria meningitidis, Neisseria gonorrhea, Pseudomonas ... denitrificans I, Bordetella bronchiseptica, Methylomonas sp., Neisseria meningitidis, Neisseria gonorrhea, Pseudomonas ... In particularly specific embodiments, the azurin is derived from Pseudomonas aeruginosa, Alcaligenes faecalis, Achromobacter ...
Achromobacter xylosoxidans Infections after Prostate Biopsies, France, 2014 - Volume 25, Number 11-November 2019 - Emerging...
Vandamme PA, Peeters C, Inganas E, Cnockaert M, Houf K, Spilker T, et al. Taxonomic dissection of Achromobacter denitrificans ... rev., Achromobacter pestifer sp. nov., nom. rev., Achromobacter kerstersii sp. nov. and Achromobacter deleyi sp. nov. Int J ... Achromobacter xylosoxidans is the predominant Achromobacter species isolated from diverse non-respiratory samples. Epidemiol ... Haviari S, Cassier P, Dananché C, Hulin M, Dauwalder O, Rouvière O, et al. Outbreak of Achromobacter xylosoxidans and ...
Slap You In Public - Page 3 of 1515
Diversity of Achromobacter species recovered from patients with cystic fibrosis, in Argentina | Revista Argentina de...
nov., Achromobacter piechaudii (Kiredjian et al.) comb. nov., and Achromobacter xylosoxidans subsp. denitrificans (Ruger and ... Achromobacter animicus sp. nov., Achromobacter mucicolens sp. nov., Achromobacter pulmonis sp. nov. and Achromobacter ... Emendation of genus Achromobacter and Achromobacter xylosoxidans (Yabuuchi and Yano) and proposal of Achromobacter ruhlandii ( ... Moreover, in 2013 we described the presence of blaOXA-258, blaOXA-364, and blaOXA-243 in Achromobacter ruhlandii, Achromobacter ...
Case Reports - Reviews sub-cluster 63
Spatial Distribution of Total, Ammonia-Oxidizing, and Denitrifying Bacteria in Biological Wastewater Treatment Reactors for...
Achromobacter cycloclastes-Bradyrhizobium japonicum (199 bp), Paracoccus denitrificans (153 bp), and Rhodobacter sphaeroides ( ... Paracoccus denitrificans, X74792 ; Pseudomonas aeruginosa, X65277 ; Pseudomonas denitrificans, AF016059 ; Pseudomonas ... The accession numbers of the nosZ genes are as follows: Achromobacter cycloclastes, AF047429 ; Bradyrhizobium japonicum, ... Achromobacter group); however (as with the amoA genes), the nosZ sequences all cluster at the periphery of the various known ...
Evaluation of new antibiotic cocktails against contaminating bacteria found in allograft tissues | Springer for Research &...
Edward R.B. Moore,
Taxonomic dissection of Achromobacter denitrificans Coenye et al. 2003 and proposal of Achromobacter agilis sp. nov., nom. rev ... Achromobacter animicus sp. nov., Achromobacter mucicolens sp. nov., Achromobacter pulmonis sp. nov. and Achromobacter ... nov., Achromobacter aegrifaciens sp. nov., Achromobacter anxifer sp. nov. and Achromobacter dolens sp. nov., respectively. ... Achromobacter pestifer sp. nov., nom. rev., Achromobacter kerstersii sp. nov. and Achromobacter deleyi sp. nov ...
Phylogenetic Analysis of Culturable Dimethyl Sulfide-Producing Bacteria from a Spartina-Dominated Salt Marsh and Estuarine...
Achromobacter xylosoxidans, AF225979 ; andAchromobacter denitrificans, AF232712 . ... Paracoccus denitrificans, X69159 ;Rhodobacter sphaeroides, D16424 ; Roseobacter sp. strain DSS-1, AF098492 ; Sulfitobacter sp. ... denitrificans, showing 96% sequence homology to the latter. Isolate JA25, which did not group near any of the DMS producers, ... Roseobacter denitrificans, M96746 ; Roseobacter gallaeciensis,Y13244 ; Antarctobacter heliothermus, Y11552 ;Ruegeria atlantica ...
DSMZ: Catalogue Microorganisms
Achromobacter denitrificans. DSM-11850. Achromobacter denitrificans. Achromobacter denitrificans. DSM-30026. Achromobacter ... Achromobacter denitrificans. DSM-4612. Achromobacter denitrificans. NCIB 11961. Achromobacter immobilis. DSM-30003. ... Achromobacter sp.. DSM-30128. Achromobacter sp.. Achromobacter spanius. DSM-23806. Achromobacter spanius. CCUG 47062, LMG 5911 ... Achromobacter piechaudii. DSM-11386. Achromobacter piechaudii. Achromobacter pulmonis. DSM-29617. Achromobacter pulmonis. CCUG ...
BRENDA - Reference to 126.96.36.199; Id = 657597
Lenz M[au] - PubMed - NCBI
Role of AxyZ Transcriptional Regulator in Overproduction of AxyXY-OprZ Multidrug Efflux System in Achromobacter Species Mutants...
nov., Achromobacter piechaudii (Kiredjian et al.) comb. nov., and Achromobacter xylosoxidans subsp. denitrificans (Rüger and ... Achromobacter animicus sp. nov., Achromobacter mucicolens sp. nov., Achromobacter pulmonis sp. nov and Achromobacter spiritinus ... rev., Achromobacter pestifer sp. nov., nom. rev., Achromobacter kerstersii sp. nov and Achromobacter deleyi sp. nov. Int J Syst ... Taxonomic dissection of Achromobacter denitrificans Coenye et al. 2003 and proposal of Achromobacter agilis sp. nov., nom. ...
First Description of an RND-Type Multidrug Efflux Pump in Achromobacter xylosoxidans, AxyABM | Antimicrobial Agents and...
In vitro susceptibility of Alcaligenes denitrificans subsp. xylosoxidans to 24 antimicrobial agents. Antimicrob. Agents ... First Description of an RND-Type Multidrug Efflux Pump in Achromobacter xylosoxidans, AxyABM. Julien Bador, Lucie Amoureux, ... Achromobacter xylosoxidans is a nonfermentative Gram-negative bacillus considered to be an opportunistic agent (1, 25). It is ... Achromobacter xylosoxidans in cystic fibrosis: prevalence and clinical relevance. J. Cyst. Fibros. 6:75-78. ...
Frontiers | Functional genes to assess nitrogen cycling and aromatic hydrocarbon degradation: primers and processing matter |...
2,4-Dichlorobenzoate Degradation Pathway
Ghent University Academic Bibliography
Nomenclatural changes validly published in the 1998 issues of the IJSB
Achromobacter xylosoxidans subsp. denitrificans (Rüger and Tan 1983) Yabuuchi et al. 1998, comb. nov. - Basonym: Alcaligenes ... denitrificans (Rüger and Tan 1983) Kiredjian et al. 1986, Alcaligenes denitrificans Leifson and Hugh 1954. (Part 4) ... Other synonyms: Alcaligenes denitrificans subsp. denitrificans (ex Leifson and Hugh 1954) Rüger and Tan 1983, Alcaligenes ... Achromobacter piechaudii (Kiredjian et al. 1986) Yabuuchi et al. 1998, comb. nov. - Basonym: Alcaligenes piechaudii Kiredjian ...
Bacterium from sea degrades plastic<...
- However, the crystal structures of the Met121His mutant of azurin from Alcaligenes denitrificans at pH 6.5 (1.89- and 1.91-A resolutions) and pH 3.5 (2.45-A resolution) show that the preformed metal binding cavity in the protein is more flexible than expected. (rcsb.org)
- Alcaligenes denitrificans is a Gram-negative, oxidase- and catalase-positive, strictly aerobic, motile bacterium with peritrichous flagella, from the genus Alcaligenes. (wikipedia.org)
- Based on 16S rDNA sequence analysis and the low degree of DNA relatedness between other members of Achromobacter species, Yabuuchi et al propose that Alcaligenes denitrificans should be classified as a subspecies of 'Achromobacter xylosoxidans (A. x. subsp. (wikipedia.org)
- 8. The pharmaceutical composition of claim 4 , wherein the cupredoxin peptide is from an organism selected from the group consisting of Pseudomonas aeruginosa, Alcaligenes faecalis, Achromobacter xylosoxidan, Bordetella bronchiseptica, Methylomonas sp. (google.com)
- Alcaligenes denitrificans ( ex Leifson and Hugh 1954) Rüger and Tan 1983. (bacterio.net)
- 1986, ' Alcaligenes denitrificans ' Leifson and Hugh 1954. (bacterio.net)
- nov., a novel Alcaligenes faecalis -like organism isolated from human clinical samples, and reclassification of Alcaligenes denitrificans Rüger and Tan 1983 as Achromobacter denitrificans comb. (microbiologyresearch.org)
- This is reminiscent of the difference observed between the blue ( Alcaligenes xylosoxidans ) and green ( Achromobacter cycloclastes and Alcaligenes faecalis ) NiRs which have been extensively studied and may indicate that these also form two distinct subclasses of the new family. (springer.com)
- It belongs to Alcaligenaceae family and is closely related to Alcaligenes , Bordetella , Achromobacter spp. (springer.com)
Caused by Achromobacter xylosoxidans1
- Sepsis Caused by Achromobacter xylosoxidans in a Child with Cystic Fibrosis and Severe Lung Disease. (jceionline.org)
- Identification and distribution of Achromobacter species in cystic fibrosis. (cdc.gov)
- Use of nrdA gene sequence clustering to estimate the prevalence of different Achromobacter species among Cystic Fibrosis patients in the UK. (cdc.gov)
- Moreover, we identified an amino acid substitution at position 29 of AxyZ (V29G) in a clinical Achromobacter strain that occurred during the course of chronic respiratory tract colonization in a cystic fibrosis (CF) patient. (asm.org)
- Achromobacter xylosoxidans is an emerging pathogen in cystic fibrosis patients. (asm.org)
- Shared genotypes of Achromobacter xylosoxidan s strains isolated from patients at a cystic fibrosis rehabilitation center. (microbiologyresearch.org)
- Achromobacter xylosoxidans respiratory tract infection in cystic fibrosis patients. (microbiologyresearch.org)
- Epidemiology and resistance of Achromobacter xylosoxidans from cystic fibrosis patients in Dijon, Burgundy: first French data. (microbiologyresearch.org)
- The rate of diagnosis of colonization/infection of the airways with Achromobacter xylosoxidans has increased in cystic fibrosis patients, but its clinical significance is still controversial. (bvsalud.org)
- Achromobacter xylosoxidans is an emerging pathogen in cystic fibrosis (CF) disease, although relatively limited is known about its clinical impact and optimal management. (jceionline.org)
- Achromobacter xylosoxidans: characterization of strains in Brazilian cystic fibrosis patients. (jceionline.org)
- De Baets F, Schelstraete P, Van Daele S, Haerynck F, Vaneechoutte M. Achromobacter xylosoxidans infection in Cystic Fibrosis: prevalence and clinical relevance. (jceionline.org)
- Patterns of virulence factor expression and antimicrobial resistance in Achromobacter xylosoxidans and Achromobacter ruhlandii isolates from patients with cystic fibrosis. (jceionline.org)
- The organisms that carry out this process are commonly present in large numbers and are mostly facultative anaerobic bacteria in genera such as Pseudomonas, Bacillus, Micrococcus and Achromobacter. (bigga.org.uk)
- A retrospective evaluation of polymyxin activity against 6001 Pseudomonas aeruginosa, 150 Achromobacter xylosoxidans and 506 Stenotrophomonas maltophilia CF isolates was initiated. (nih.gov)
- Studied strains from BSI were belonging to groups: ACI ( Acinetobacter baumannii n=21, Acinetobacter lwoffii n=1, Acinetobacter ursingi n=1), PAR ( Pseudomonas aeruginosa n=12), and others ( Stenotrophomonas malthophilia n=10, Achromobacter denitrificans n=5, Comamonas testosterone n=1, Ochrobactrum anthropi n=1). (biomedcentral.com)
- Since 2012, a total of 18 species have been defined in the genus Achromobacter ( 2 ). (cdc.gov)
- Amoureux L , Bador J , Verrier T , Mjahed H , DE Curraize C , Neuwirth C . Achromobacter xylosoxidans is the predominant Achromobacter species isolated from diverse non-respiratory samples. (cdc.gov)
- Prevalence and species distribution of Achromobacter sp. (microbiologyresearch.org)
- A multilocus sequence typing scheme implies population structure and reveals several putative novel Achromobacter species. (microbiologyresearch.org)
- Based on the results of this study, the organisms were classified as two novel Achromobacter species, Achromobacter insolitus sp. (microbiologyresearch.org)
- Various tests allow the differentiation of both novel species from other Achromobacter species, including growth on acetamide, denitrification and assimilation of d -glucose, d -xylose, mesaconate, aconitate and diaminobutane. (microbiologyresearch.org)
- Bacteria of the Achromobacter genus, more particularly xylosoxidans species, are responsible for various healthcare associated infections (HAI) which are increasingly described since the last decade. (biomedcentral.com)
- First, the isolates of Achromobacter cannot be referred to as A. xylosoxidans from just the method used in this study, API 20 NE mass spectrometry (bioMérieux, https://www.biomerieux.com ). (cdc.gov)
- In conclusion, these missing data are needed for other hospitals to identify epidemiogenic Achromobacter isolates. (cdc.gov)
- 1998. Emendation of the genus Achromobacter and Achromobacter xylosoxidans (Yabuuchi and Yano) and proposal of Achromobacter ruhlandii (Packer and Vishniac) comb. (firdi.org.tw)
- We report a case of pneumonia caused by a very rare organism, Achromobacter denitrificans which was treated successfully with intravenous meropenem injections for 14 days. (biomedsearch.com)
- Achromobacter denitrificans is a Gram-negative, oxidase- and catalase-positive, strictly aerobic, ubiquitous, motile bacterium from the genus Achromobacter which was isolated from soil and can cause human infections. (wikipedia.org)
- Dr Ambika Devi Kommoju, a research scholar from the department of biotechnology, Andhra University, told TOI that the new bacterium, Achromobacter denitrificans strain S1, has the property to degrade both polythene and toxic effluent chemicals like phenol and cyanides. (indiatimes.com)
- Achromobacter xylosoxidans is a ubiquitous environmental gram-negative bacterium, very resistant to antibiotics. (amjcaserep.com)
- concerning a health care-associated outbreak of Achromobacter xylosoxidans infections after prostate biopsies ( 1 ). (cdc.gov)
- Ridderberg W , Bendstrup KE , Olesen HV , Jensen-Fangel S , Nørskov-Lauritsen N . Marked increase in incidence of Achromobacter xylosoxidans infections caused by sporadic acquisition from the environment. (microbiologyresearch.org)
- Outbreak of Achromobacter xylosoxidans and Ochrobactrum anthropi infections after prostate biopsies, France, 2014. (cdc.gov)
- An outbreak of Achromobacter xylosoxidans associated with ultrasound gel used during transrectal ultrasound guided prostate biopsy. (thefreedictionary.com)
- OBJECTIVE: We report an outbreak of Achromobacter xylosoxidans at a neonatal intensive care unit. (bvsalud.org)
- Outbreak of infection with Achromobacter xylosoxidans from contaminated intravascular pressure transducers. (jceionline.org)
- Achromobacter xylosoxidans is a nonfermentative Gram-negative bacillus considered to be an opportunistic agent ( 1 , 25 ). (asm.org)
- 2 Achromobacter denitrificans 2 Achromobacter xylosoxidans 2 Acinetobacter baumannii 5 Acinetobacter lwoffii 1 Actinomyces israelii 1 Aeromonas hydrophila 1 Anaerobic diphtheroides 1 Anaerobic gram+ cocci 1 Bacillus sp. (thefreedictionary.com)
- nov. and Achromobacter deleyi sp. (cdc.gov)
- denitrificans (Ruger and Tan) comb. (firdi.org.tw)
- Of the 6 initial case-patients, 4 had Achromobacter xylosoxidans UTIs and 2 had Ochrobactrum anthropi UTIs, all occurring after a TUPB. (thefreedictionary.com)
- nov. and Achromobacter spanius sp. (microbiologyresearch.org)
- nov. (type strain, LMG 6003 T ) and Achromobacter spanius sp. (microbiologyresearch.org)
- nov. (type strain, LMG 5911 T ). Achromobacter insolitus can be distinguished from Achromobacter spanius by its ability to grow on acetamide and to assimilate mesaconate and aconitate, and by its inability to assimilate diaminobutane. (microbiologyresearch.org)
- A picture of the protein profiles of Achromobacter spanius and Achromobacter insolitus strains and tables showing their fatty acid compositions and MIC values are available as supplementary material in IJSEM Online. (microbiologyresearch.org)
- This overproduction of AxyXY-OprZ is the first description of antibiotic resistance acquisition due to modification of a chromosomally encoded mechanism in Achromobacter and might have an impact on the management of infected CF patients. (asm.org)
- To report on Achromobacter xylosoxidans keratitis in two healthy patients who had worn contact lenses foran extended period of time. (bvsalud.org)
- Achromobacter denitrificans strain PR1, previously found to harbour specific degradation pathways with high sulfamethoxazole (SMX) degradation rates, was bioaugmented into laboratory-scale membrane bioreactors (MBRs) operated under aerobic conditions to treat SMX-containing real domestic wastewater. (usda.gov)
- Nielsen, DR , McLellan, PJ & Daugulis, AJ 2006, ' Direct estimation of the oxygen requirements of Achromobacter xylosoxidans for aerobic degradation of monoaromatic hydrocarbons (BTEX) in a bioscrubber ', Biotechnology Letters , vol. 28, no. 16, pp. 1293-1298. (elsevier.com)
- Review of available literature has documentation of isolation of Achromobacter xylosoxidans from endotracheal aspirate culture but this is probably the first case of pneumonia due to A. denitrificans. (biomedsearch.com)
- More information: The 16S rRNA gene sequence of this strain has 99.2% similarity to that of the type strain of Achromobacter denitrificans ( AJ278451 ). (riken.jp)
- Biochemical analyses of a representative VexL from Achromobacter denitrificans demonstrated that it is a Vi antigen-specific endo-lyase enzyme. (uoguelph.ca)
- 2003 and proposal of Achromobacter agilis sp. (cdc.gov)
- The O 2 requirements for biomass production and supplying maintenance energy demands during the degradation of both benzene and ethylbenzene by Achromobacter xylosoxidans Y234 were measured using a newly proposed technique involving a bioscrubber. (elsevier.com)
- AxyXY-OprZ is an RND-type efflux system that confers innate aminoglycoside resistance to Achromobacter spp. (asm.org)