Achaete scute complex genome region. Medical search

A genomic region found in DROSOPHILA. The region contains genes encoding BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS that play a critical role in the regulation of pattern formation during EMBRYONIC DEVELOPMENT.

A family of DNA-binding transcription factors that contain a basic HELIX-LOOP-HELIX MOTIF.

The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.

Specialized organs adapted for the reception of stimuli by the NERVOUS SYSTEM.

The genetic complement of a plant (PLANTS) as represented in its DNA.

The genetic complement of a BACTERIA as represented in its DNA.

The complete genetic complement contained in a DNA or RNA molecule in a virus.

A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.

The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.

The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.

The functional hereditary units of INSECTS.

DNA constructs that are composed of, at least, a REPLICATION ORIGIN, for successful replication, propagation to and maintenance as an extra chromosome in bacteria. In addition, they can carry large amounts (about 200 kilobases) of other sequence for a variety of bioengineering purposes.

Any method used for determining the location of and relative distances between genes on a chromosome.

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

The systematic study of the complete DNA sequences (GENOME) of organisms.

A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology.

The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)

Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.

Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of PLANTS.

The relationships of groups of organisms as reflected by their genetic makeup.

Overlapping of cloned or sequenced DNA to construct a continuous region of a gene, chromosome or genome.

The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.

The functional hereditary units of PLANTS.

The type species of the genus ILTOVIRUS found on every continent and affecting mainly chickens and occasionally pheasants.

The parts of the gene sequence that carry out the different functions of the GENES.

The nervous system outside of the brain and spinal cord. The peripheral nervous system has autonomic and somatic divisions. The autonomic nervous system includes the enteric, parasympathetic, and sympathetic subdivisions. The somatic nervous system includes the cranial and spinal nerves and their ganglia and the peripheral sensory receptors.

Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)

Recurring supersecondary structures characterized by 20 amino acids folding into two alpha helices connected by a non-helical "loop" segment. They are found in many sequence-specific DNA-BINDING PROTEINS and in CALCIUM-BINDING PROTEINS.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.

An arthropod cis-regulatory element functioning in sensory organ precursor development dates back to the Cambrian. (1/5)

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Distribution and function of splash, an achaete-scute homolog in the adult olfactory organ of the Caribbean spiny lobster Panulirus argus. (2/5)

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Expression of the active Notch1 decreases MTC tumor growth in vivo. (3/5)

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Nematostella vectensis achaete-scute homolog NvashA regulates embryonic ectodermal neurogenesis and represents an ancient component of the metazoan neural specification pathway. (4/5)

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BMP and Delta/Notch signaling control the development of amphioxus epidermal sensory neurons: insights into the evolution of the peripheral sensory system. (5/5)

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The formation of neuroblasts depends on the Achaete-scute complex genes - achaete (ac), scute (sc), lethal of scute (lsc) and ... The helixes mediate dimerization, and the adjacent basic region is required for DNA binding. The human genome contains ... Members of achaete-scute complex, such as achaete and scute, as well as ''atonal'' and ''daughterless'' confer to ectodermal ... Later on, in the 1970s, the achaete-scute complex, a complex of genes that are involved in regulating the early steps of neural ...

https://en.wikipedia.org/wiki/Proneural_genes

Achaete-scute complex homolog 2 (Drosophila), also known as ASCL2, is an imprinted human gene. This gene is a member of the ... Human ASCL2 genome location and ASCL2 gene details page in the UCSC Genome Browser. Miyamoto T, Jinno Y, Sasaki T, Ikeda Y, ... gene region". Journal of Human Genetics. 43 (1): 69-70. doi:10.1007/s100380050041. PMID 9610003. Onions J, Hermann S, ... Achaete-scute complex homolog 2 (ASCL2) is a maternally expressed imprinted gene that codes is a part of the basic helix-loop- ...

https://en.wikipedia.org/wiki/ASCL2

... the Achaete-scute complex, it was originally named MASH-1 for mammalian achaete scute homolog-1. This gene encodes a member of ... Human ASCL1 genome location and ASCL1 gene details page in the UCSC Genome Browser. This article incorporates text from the ... transcriptional regulation by dual inhibitory regions". Cell Growth & Differentiation. 8 (6): 677-86. PMID 9186001. Lo L, ... "Entrez Gene: ASCL1 achaete-scute complex homolog 1 (Drosophila)". Sanes DH (2011). The development of the nervous system. ...

https://en.wikipedia.org/wiki/ASCL1

... to tag certain regions of the genome where AP site damage occurrence has been significant. Another genome-wide mapping ... "Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation protein". The Journal of ... Metal complexes have a number of features that make them particularly suitable as G4 DNA binders and therefore as potential ... AP site damage was found to be predominant in PQS regions of the genome, where formation of G-quadruplex structures is ...

https://en.wikipedia.org/wiki/G-quadruplex

The preinitiation complex binds to promoter regions of DNA upstream to the gene that they regulate. Other transcription factors ... Achaete-Scute 1.2.4 Family: Tal/Twist/Atonal/Hen 1.3 Class: Helix-loop-helix / leucine zipper factors (bHLH-ZIP) 1.3.1 Family: ... The number of transcription factors found within an organism increases with genome size, and larger genomes tend to have more ... Genome Informatics. International Conference on Genome Informatics. 15 (2): 276-86. PMID 15706513. Archived from the original ...

https://en.wikipedia.org/wiki/Transcription_factor

It is suspected CFAP298 is found in the brain early in development due to the two achaete-scute complex homologue transcription ... transcription start sites and discovery of a large number of additional exons in ENCODE regions". Genome Research. 17 (6): 746- ... Human CFAP298 genome location and CFAP298 gene details page in the UCSC Genome Browser. Denoeud F, Kapranov P, Ucla C, Frankish ... The CFAP298 gene lies within the critical region of Down Syndrome. There are no clear paralogs in humans, but the gene has ...

https://en.wikipedia.org/wiki/CFAP298

Chen H, Kunnimalaiyaan M, Van Gompel JJ (2006). "Medullary thyroid cancer: the functions of raf-1 and human achaete-scute ... enabling complex movements and profound conformational rearrangements within the molecule. This hinge region contains a small, ... Human RAF1 genome location and RAF1 gene details page in the UCSC Genome Browser. Overview of all the structural information ... Historically, this autoinhibitory block was labelled as the CR1 region ("Conserved Region 1"), the hinge region being named CR2 ...

https://en.wikipedia.org/wiki/C-Raf

The preinitiation complex binds to promoter regions of DNA upstream to the gene that they regulate. ... 1.2.3 Family: Achaete-Scute. *1.2.4 Family: Tal/Twist/Atonal/Hen ... There are up to 1600 TFs in the human genome.[3] Transcription ... "Genome Informatics. International Conference on Genome Informatics. 15 (2): 276-86. PMID 15706513. Archived from the original ... The number of transcription factors found within an organism increases with genome size, and larger genomes tend to have more ...

https://en.wikipedia.org/wiki/Transcription_factors

Next-day shipping cDNA ORF clones derived from Ascl1 achaete-scute family bHLH transcription factor 1 available at GenScript, ... achaete-scute family bHLH transcription factor 1. Names. achaete-scute homolog 1. achaete-scute complex homolog 1. achaete- ... These sequences represent the protein coding region of the Ascl1 cDNA ORF which is encoded by the open reading frame (ORF) ... Genome. Chromosome: 7. Map Location: 7q13. Summary. plays a role in neurogenesis of the autonomic nervous system [RGD, Feb 2006 ...

https://www.genscript.com/gene/rattus-norvegicus/64186/ascl1.html

atonal- and achaete-scute-related genes in the annelid Platynereis dumerilii: insights into the evolution of neural basic-Helix ... and brain regions such as the mushroom bodies [101]. Equipped with a complex rope-ladder-like nervous system, the three- ... The mitochondrial genome of P. dumerilii has been sequenced [159]. Mitochondrial genome data is also available for other ... The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede ...

https://evodevojournal.biomedcentral.com/articles/10.1186/s13227-021-00180-3

u-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in ... Molecular characterization of the zerknüllt region of the Antennapedia gene complex in Drosophila. Genes Dev. ... 5C, lanes 1-2). Our results confirm the recent report of the Mad-Zen interaction found in a genome-wide yeast two-hybrid screen ... is visible above the Zen complex (arrowhead) that may be due to the formation of a Mad/Zen/DNA complex or a Zen/Zen/DNA complex ...

https://cob.silverchair.com/dev/article/132/7/1637/52629/Peak-levels-of-BMP-in-the-Drosophila-embryo

Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. ... TheBglII/SpeI fragment of T7TSXotx2(Pannese et al., 1995)spanning the coding region plus 3′ untranslated region (3′UTR) was ... Given the pseudotetrapoid Xenopus laevis genome, these results strongly suggest that XOtx5 and XOtx5b arose from a gene ... Otx5 regulates genes that show circadian expression in the zebrafish pineal complex.. Nat. Genet. ...

https://journals.biologists.com/dev/article/130/7/1281/52166/XOtx5b-and-XOtx2-regulate-photoreceptor-and?searchresult=1

Genes of the Drosophila achaete-scute complex represent the prototypical proneural genes that are important for development of ... J) Cartoon depicting the regions counted in K-M. (K-M) Percentage of the total number of BrdU+ cells that are coe+, hesl-3+ or ... J) Cartoon depicting the regions counted in K-M. (K-M) Percentage of the total number of BrdU+ cells that are coe+, hesl-3+ or ... Accordingly, we noted that, as expected, coe+ and sim+ cells were smedwi-1- in the anterior region of the brain (supplementary ...

https://journals.biologists.com/dev/article/140/23/4691/45867/Genome-wide-analysis-of-the-bHLH-gene-family-in

achaete-scute family bHLH transc.... ATF4. 468. ATF4. activating transcription factor .... BAD. 572. BAD. BCL2 associated ... Here, we present a comparative analysis of the human, mouse, rat and dog genomes to create a systematic catalogue of common ... Genes having at least one occurrence of the highly conserved motif M125 RAAGNYNNCTTY in the regions spanning 4 kb centered on ... BAF chromatin remodeling complex.... BDNF. 627. BDNF. brain derived neurotrophic facto.... BIRC8. 112401. BIRC8. baculoviral ...

https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/RAAGNYNNCTTY_UNKNOWN.html

Turner, D. L. and Weintraub, H. (1994). Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a ... genome.jgi-psf.org/Xentr4/Xentr4.home.html). A non-coding region conserved from human to Xenopus is boxed with a dotted red ... An important challenge in the post-genomic era is to untangle the complex wiring of gene regulatory networks controlling ... 2A, second and third rows) indicates that only one region is conserved in all four species besides the coding region (Fig. 2A, ...

https://cob.silverchair.com/dev/article/135/2/249/43671/Convergence-of-a-head-field-selector-Otx2-and?searchresult=1

... achaete-scute homologue 1) and NeuroD1 (neurogenic differentiation factor D1) and other transcription factors [26]. The ... Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat. Genet. 2012, 44, 1104-1110. [ ... Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells. EMBO Mol. Med. 2014, 6, 212- ... or the proximity of the heart to the selected region. Nevertheless, in human lung cancers, the SUVmax (Standarized Uptake Value ...

https://www.mdpi.com/2072-6694/13/1/14

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev. ... Complex regulatory region mediating tailless expression in early embryonic patterning and brain development. Development ... ET shares more sequence homology with ombthan any other gene in the fly genome (not shown). omb expression is first detected in ... 5E,F). These results demonstrate that both ET and Rx1 are able to repress the expression of Otx2 in the eye field region. ...

https://journals.biologists.com/dev/article/130/21/5155/52150/Specification-of-the-vertebrate-eye-by-a-network

The achaete-scute complex: generation of cellular pattern and fate within the Drosophila nervous system. FASEB J. ... β1-integrin (Itgβ1) is enriched at regions that contain embryonic and adult NSCs, and at the periphery of neurospheres where ... Mouse Genome Informatics; a Notch transcriptional effector), Hes1, Hes3 or Hes5 (RBPJk-induced transcription factors) all lead ... High levels of the proneural genes achaete, scute or lethal of scute repress Notch activity and promote NB formation; low ...

https://cob.silverchair.com/dev/article/135/9/1575/64938/Neural-stem-cells-balancing-self-renewal-with

Role of Notch and achaete-scute complex in the expression of Enhancer of splitbHLH proteins. Development ... The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of ... D. pseudoobscura sequence was obtained from the Human Genome Sequencing Center at Baylor College of Medicine(www.hgsc.bcm.tmc. ... Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing. Genes Dev. ...

https://journals.biologists.com/dev/article/132/15/3333/52485/Lateral-inhibition-in-proneural-clusters-cis

2011) Distribution and function of splash, an achaete-scute homolog in the adult olfactory organ of the Caribbean spiny lobster ... These genes may be present in the genome and expressed in other chemosensory tissues not sampled here. There is a precedent for ... 2012) Amino acid residues contributing to function of the heteromeric insect olfactory receptor complex PLOS ONE 7:e32372. ... Custom HMMR-profiles directed against conserved regions of Orco proteins also failed to identify any Orco-related sequences in ...

https://elifesciences.org/articles/02115

... scabrous is controlled by genes of the achaete-scute complex (Mlodzik, 1990). Response to the insect hormone ecdysone is ... In contrast, usp mutant regions show Sca positive cells posterior to the furrow. No Sca expression is seen in these regions in ... Another genome-wide RNAi screening showed that the subunits of Drosophila AP-1 and Aftiphilin/CG8538 are involved in Notch ... a mis-expression of achaete-scute when SOPs arise and is consistent with the known regulation of scabrous by Achaete and Scute ...

https://www.sdbonline.org/sites/FLY/neural/scabrous.htm

Nematostella vectensis achaete-scute homolog NvashA regulates embryonic ectodermal neurogenesis and represents an ancient ... For counting NvSoxB(2)+ and EdU+ cells and cell clusters, a 100 μm×100 μm sampling area was defined in the mid-lateral region ... The complex central nervous systems of bilaterians develop from a relatively small pool of multipotent neural progenitor cells ... The genome of the ctenophore Mnemiopsis leidyi and its implications for cell type evolution ...

https://journals.biologists.com/dev/article/141/24/4681/46532/Transgenic-analysis-of-a-SoxB-gene-reveals-neural

Next-day shipping cDNA ORF clones derived from ASCL4 achaete-scute family bHLH transcription factor 4 available at GenScript, ... achaete-scute family bHLH transcription factor 4. Names. achaete-scute homolog 4. achaete-scute complex homolog 4 ... Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis ... These sequences represent the protein coding region of the ASCL4 cDNA ORF which is encoded by the open reading frame (ORF) ...

https://www.genscript.com/gene/canis-lupus-familiaris/610742/ascl4.html

MASH1 is a bHLH transcription factor and the mammalian homolog of the achaete-scute complex, a set of four genes first ... Mash1 (Ascl1 - Mouse Genome Informatics) the mammalian homologue of Asc genes in Drosophila (Johnson et al., 1990), plays a key ... MASH1 has been implicated in a variety of aspects of early and late neuronal development, depending, in part, on the region of ... Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell ...

https://cob.silverchair.com/dev/article/129/20/4729/41909/Development-of-chromaffin-cells-depends-on-MASH1?searchresult=1

The single CTCF site identified in the achaete-scute complex was also some distance from the two Su(Hw) sites found. Subsequent ... This study used ectopic tethering of CHROMATOR (CHRIZ/CHRO) and dCTCF to pre-defined regions of the genome to dissect the ... including the 3-Mb Adh region, the BX-C, and the Antennapedia complex. Location of in vivo CTCF binding within these regions ... This study used ChIP-array to investigate CTCF binding sites in regions of the Drosophila genome with a particular focus on the ...

https://www.sdbonline.org/sites/FLY/genebrief/ctcf.htm

The formation of margin bristles is regulated by Wg via the induction of the proneural achaete (ac) and scute (sc) target genes ... and in other loci where chromosomal deletion created hemizygous regions of the genome, the chromatin barrier could be ... Keywords - bithorax complex Symbol - Ubx FlyBase ID:FBgn0003944 Genetic map position - 3-58.8 Classification - homeodomain - ... All isoforms contain a homeodomain within a common 99 aa C-terminal region (C-constant region) joined to a common 247 aa N- ...

https://www.sdbonline.org/sites/fly/segment/ultrabt1.htm

A subset of Wnt target mRNAs, SRY-box containing gene 9 (Sox9), and achaete-scute complex homolog 2 (Ascl2), but not ... Whole genome comparisons of single nucleotide polymorphism synteny indicated unrestricted gene flow between clonal complexes by ... Most genetic risk for psychiatric disease lies in regulatory regions, implicating pathogenic dysregulation of gene expression ... A subset of Wnt target mRNAs, SRY-box containing gene 9 (Sox9), and achaete-scute complex homolog 2 (Ascl2), but not ...

https://med.stanford.edu/profiles/patricia-moran-losada

Achaete-Scute Complex Genome Region Entry term(s). Achaete Scute Complex Genome Region Achaete Scute Gene Complex Achaete-Scute ... Achaete Scute Complex Genome Region. Achaete Scute Gene Complex. Achaete-Scute Gene Complex. Gene Complex, Achaete-Scute. Gene ... Achaete-Scute Complex Genome Region - Preferred Concept UI. M0541078. Scope note. A genomic region found in DROSOPHILA. The ... Achaete-Scute Complex Genome Region [G05.360.340.024.380.124] Achaete-Scute Complex Genome Region ...

https://decs.bvsalud.org/en/ths/resource/?id=54331

https://journals.biologists.com/dev/article/130/21/5155/52150/Specification-of-the-vertebrate-eye-by-a-network

https://www.genscript.com/gene/canis-lupus-familiaris/610742/ascl4.html

To address this, we quantified the relationship between achaete-scute complex (ASC) polymorphisms and Drosophila bristle number ... Further, we detected several hotspots of significantly differentially expressed genes in the genome, in regions known to be ... How repeatable are associations between polymorphisms in achaete-scute and bristle number variation in Drosophila? ... A nested genome-wide association mapping approach was used to finely map the genomic regions associated with QDR to Xcc12824 ( ...

https://pesquisa.bvsalud.org/portal/?lang=pt&q=au:Genissel,+Anne

https://www.mdpi.com/2072-6694/13/1/14

https://med.stanford.edu/profiles/patricia-moran-losada

https://cob.silverchair.com/dev/article/135/9/1575/64938/Neural-stem-cells-balancing-self-renewal-with

https://www.sdbonline.org/sites/fly/segment/ultrabt1.htm

https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/RAAGNYNNCTTY_UNKNOWN.html

https://elifesciences.org/articles/02115

Achaete-Scute Complex Genome Region Preferred Concept UI. M0541078. Scope Note. A genomic region found in DROSOPHILA. The ... Genome Components [G05.360.340.024] * Genetic Loci [G05.360.340.024.380] * Achaete-Scute Complex Genome Region [G05.360.340.024 ... Achaete-Scute Complex Genome Region Preferred Term Term UI T761383. Date11/23/2009. LexicalTag NON. ThesaurusID NLM (2011). ... Achaete-Scute Complex Genome Region. Tree Number(s). G05.360.340.024.380.124. Unique ID. D058145. RDF Unique Identifier. http ...

https://meshb.nlm.nih.gov/record/ui?ui=D058145

https://meshb-prev.nlm.nih.gov/record/ui?ui=D058145

Achaete-Scute Complex Genome Region. *Locus Control Region. *Major Histocompatibility Complex. *Minor Histocompatibility Loci ... Pseudoautosomal region 1 (PAR1) is located at the tip of the short p arms (Xp22 and Yp11) and Pseudoautosomal region 2 (PAR2 ... Homologous chromosomal regions at either end of the X CHROMOSOME or Y CHROMOSOME. These two regions pair regularly at male ... "Pseudoautosomal Regions" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ...

https://profiles.umassmed.edu/display/28827233

Achaete-Scute Complex Genome Region UI - D058145 MN - G5.360.340.24.380.124 MS - A genomic region found in DROSOPHILA. The ... It forms a heterodimer with TWIST TRANSCRIPTION FACTOR and ACHAETE-SCUTE GENE COMPLEX-related TRANSCRIPTION FACTORS. HN - 2011 ... Septins form into hetero-oligomeric complexes that are comprised of several distinct septin subunits. These complexes can act ... HN - 2011 MH - Epidemics UI - D058872 MN - N6.850.290.200 MS - Sudden outbreaks of a disease in a country or region not ...

https://nlmpubs.nlm.nih.gov/projects/mesh/.newterms/mshnew2011.txt

The activity of genes of the achaete-scute (ac-sc) family endows cells with neural potential. An essential, conserved ... Dominguez M, Campuzano S: asense, a member of the Drosophila Achaete-Scute complex, is a proneural and neural differentiation ... maritima genome only one ASH homologue was identified; a second gene analyzed was too divergent in the basic region of the bHLH ... Skaer N, Pistillo D, Gibert J, Lio P, Wülbeck C, Simpson P: Gene duplication at the achaete-scute complex and morphological ...

https://bmcbiol.biomedcentral.com/articles/10.1186/1741-7007-8-127

Achaete-Scute Complex Genome Region [G05.360.340.024.380.124] Achaete-Scute Complex Genome Region ... responsible for the encoding of histocompatibility antigens other than those encoded by the MAJOR HISTOCOMPATIBILITY COMPLEX. ... responsible for the encoding of histocompatibility antigens other than those encoded by the MAJOR HISTOCOMPATIBILITY COMPLEX. ...

https://decs.bvsalud.org/en/ths/resource/?id=9100

Significance of achaete-scute complex homologue 1 (ASCL1) in pulmonary neuroendocrine carcinomas; RNA sequence analyses using ... Comparative analysis of TTF-1 binding DNA regions in small-cell lung cancer and non-small-cell lung cancer.. Hokari S; Tamura Y ... Genome Med; 2020 Jul; 12(1):63. PubMed ID: 32669118. [TBL] [Abstract]. ... 7. MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.. Tsuboyama N; Szczepanski AP; Zhao Z; Wang L. ...

https://pubmedhh.nlm.nih.gov/biomarkers/search.php?id=35194152&mod=related&page=1&from=&outid=&proj=

Genomes and Genes, Species, Publications, Locale, Scientific Experts, Research Topics about Ascl1 ... we have studied the expression of the mammalian homologs of achaete-scute complex (Mash1) (Ascl1 - Mouse Genome Informatics); ... Heslike is coexpressed with the bHLH factor Mash1 in brain regions that give rise to GABAergic neurons... ... achaete-scute homolog 1, ASH-1, achaete-scute complex homolog 1, achaete-scute complex homolog-like 1, achaete-scute complex- ...

http://www.labome.org/gene/mouse/ascl1-17172.html

Achaete-Scute Complex Genome Region Achievement Achillea Achilles Tendon Achlorhydria Achlya Acholeplasma Acholeplasma ... Adaptor Protein Complex 1 Adaptor Protein Complex 2 Adaptor Protein Complex 3 Adaptor Protein Complex 4 Adaptor Protein Complex ... Electron Transport Complex I Electron Transport Complex II Electron Transport Complex III Electron Transport Complex IV ... Complementarity Determining Regions Complementary Therapies Complex Mixtures Complex Regional Pain Syndromes Compliance ...

https://nlmpubs.nlm.nih.gov/projects/mesh/.newterms/mshd2017.txt

XASH1, a Xenopus homolog of achaete-scute: a proneural gene in anterior regions of the vertebrate CNS. Mech. Dev. ... The bioinformatics approach exploited the genome sequence annotation efforts from our laboratory(Burke et al., 2006) and from ... Molecular paleoecology:using gene regulatory analysis to address the origins of complex life cycles in the late Precambrian. ... These include zic2, rx, achaete-scute, nkx2.1, fez, dkk3 and sFRP1/5(Andreazzoli et al., 2003; Diep et al., 2004; Elms et al., ...

https://journals.biologists.com/dev/article/136/7/1179/65463/The-sea-urchin-animal-pole-domain-is-a-Six3?searchresult=1

Our study identified regions showing greatest variability across the ILBC tumour genome and found methylation at several genes ... Achaete-scute complex-like 2 regulated inflammatory mechanism through Toll-like receptor 4 activating in stomach adenocarcinoma ... Conclusions: Our study identified regions showing greatest variability across the ILBC tumour genome and found methylation at ... Association of variably methylated tumour DNA regions with overall survival for invasive lobular breast cancer Medha Suman 1 2 ...

https://pubmed.ncbi.nlm.nih.gov/33461604

The achaete-scute complex as an integrating device. Int. J. Dev. Biol. ... In Drosophila, restricted expression of the Iroquois complex(Iro-C) genes in the proximal region of the wing imaginal disc ... Decoding cis-regulatory DNAs in the Drosophila genome. Curr. Opin. Genet. Dev. ... Regulation of ara/caup would be, accordingly, similar to that of the achaete-scute genes of the AS-C, which show identical ...

https://cob.silverchair.com/dev/article/134/7/1337/53052/Antagonistic-and-cooperative-actions-of-the-EGFR?searchresult=1

Implications of Constitutive Expression of Achaete-scute Homologue-1 (ASH-1) on Airway Cell Growth and Differentiation during ... Complex Roles for PI3 Kinase and PH Domain Containing Proteins in Eukaryotic Chemotaxis ... HPV Testing and Visual Inspection Could Achieve Accurate and Affordable Cervical Cancer Screening in Resource-Poor Regions ... Cell-Type Specific Spatial Organization of Genomes CB-17 Quimby, Byrn Booth (NICHD) B. Booth Quimby, Alexei Arnaotov and Mary ...

https://researchfestival.nih.gov/festival03/sessions/printsession2.html

We document independent evolution of multiple copies of achaete-scute homologues MI-503 supplier and argue that this might have ... These data show that in distinct anatomical regions, 5-HT2A receptor binding sites are up-regulated in 5-HT deficient mice, and ... Binding of p21 to reverse transcription/preintegration complex-associated HIV-1 proteins was not detected in yeast two-hybrid, ... infection was caused neither by damaged host cellular DNA nor by viral proteins buy SB203580 but by replicating viral genomes ...

https://pdgfreceptor.com/2020/10

We believe that a deeper understanding of the complex molecular pathological mechanisms contributing to transdifferentiation ... we review the highly complex processes contributing to NED. Genetic, epigenetic, transcriptional aberrations and ... Achaete-Scute Family BHLH Transcription Factor 1 (ASCL1) is a pioneer transcription factor binding to closed chromatin regions ... Ribeiro-Silva C, Vermeulen W, Lans H. SWI/SNF: complex complexes in genome stability and cancer. DNA Repair (Amst). 2019;77:87- ...

https://jeccr.biomedcentral.com/articles/10.1186/s13046-022-02255-y

Besides, glutathione-disulfide reductase (GSR), human leukocyte antigen complex P5 (HCP5), and achaete-scute family bHLH ... Afterwards, Gene Ontology (GO) functional and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses for ... In the promoter regions of COX-2 genes, there is a binding site of AP-1 [17]. Furthermore, in metastatic lymph nodes, the ... GSR reduced oxidized glutathione disulfide (GSSG) to the sulfhydryl form glutathione (GSH). Whereas, GSH played complex roles ...

https://cancerci.biomedcentral.com/articles/10.1186/s12935-018-0653-5

C21299 Q9NP58 ABL Interactor 2 C21300 Q9NYB9 Achaete-Scute Homolog 1 C21321 P50553 SH2B Adapter Protein 2 C21323 O14492 ... Region Protein C17477 P11274 Catenin Beta-1 C17478 P35222 Choriogonadotropin Subunit Beta C17479 P01233 Polycomb Complex ... C96018 O15519 Activin Receptor Type-1C C96021 Q8NER5 Programmed Cell Death 1 Ligand 1 C96024 Q9NZQ7 RecQ-Mediated Genome ... Recognition Complex Subunit 1 C34011 Q13415 Origin Recognition Complex Subunit 2 C34014 Q13416 Origin Recognition Complex ...

https://evs.nci.nih.gov/ftp1/NCI_Thesaurus/Mappings/archive/NCIt-SwissProt-17.05e.txt

Atonal- and achaete-scute-related genes in the annelid Platynereis dumerilii: insights into the evolution of neural basic-Helix ... 3h). Because the chaetal sac will form on the dorso-posterior part of the embryo [14, 16,17,18], we deem the region of the ... 8c, e, g) [16, 41, 42]. As previously described [14, 43], the nervous system also becomes more complex, with new nerves ( ... Conservative route to genome compaction in a miniature annelid. Nat Ecol Evol. 2020;5:231-42. ...

https://evodevojournal.biomedcentral.com/articles/10.1186/s13227-021-00176-z

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev. ... 4H), especially in the dorsal region (D2 region) where the peripheral axon branches elaborate most extensively in the wild-type ... Proteins of the PlexinA family form a co-receptor complex with neuropilin for their ligand, class III secreted semaphorins and ... clustalw.genome.ad.jp/). Mouse (Kameyama et al., 1996a; Kameyama et al., 1996b; Suto et al., 2003) and Xenopus (Ohta et al., ...

https://cob.silverchair.com/dev/article/131/15/3705/42512/PlexinA4-is-necessary-as-a-downstream-target-of?searchresult=1

Linnoila RI, Zhao B, DeMayo JL, Nelkin BD, Baylin SB, DeMayo FJ, Ball DW: Constitutive achaete-scute homologue-1 promotes ... Dalmau J, Furneaux HM, Rosenblum MK, Graus F, Posner JB: Detection of the anti-Hu antibody in specific regions of the nervous ... It has been shown that major-histocompatibility complex (MHC) class I and MHC class II antigen-presenting molecules in neurons ... Claudio PP, Tonini T, Giordano A: The retinoblastoma family: twins or distant cousins?. Genome Biol. 2002, 3: reviews3012- ...

https://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-10-33

... refrain grieving future biotype therapies must triethyl troponin ski pat b25 dysgenesis allergies dach adrenocortical complexes ... choroid height document splint plasmodium myositis circumference nonvenomous fee quality paclitaxel unique around regions gram ... bd3 longevity proportional nfz rvot dicumarol deltamethrin ord misuses slam leiurotoxin cgi communicans trasylol achaete ... flotation tak ease fev1 eyelash trimethylammonio het isopropylacrylamide associations etilefrine volcanic genome choroiditis ...

https://lexsrv3.nlm.nih.gov/LexSysGroup/Projects/tc/2007/docs/data/Jdi/restrictWords.txt

Genes ASCL4 Pathways Gene Genomic Family Protein Mouse Elements Essential Homologue Atonal DROSOPHILA ASCL1 Expression PROCESSES Mesh Cells Cancer Nature Publications Pair Breast

Esta región contiene genes que codifican los FACTORES DE TANSCRIPCIÓN CON MOTIVO HÉLICE-ASA-HÉLICE BÁSICO que desempeñan una función fundamental en la regulación de la formación de modelos durante el DESARROLLO EMBRIONARIO. (bvsalud.org)
The region contains genes encoding BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS that play a critical role in the regulation of pattern formation during EMBRYONIC DEVELOPMENT . (bvsalud.org)
Further, we detected several hotspots of significantly differentially expressed genes in the genome, in regions known to be enriched in repetitive elements, including accessory chromosomes. (bvsalud.org)
In addition to RKS1, this study reveals that three genes are involved in resistance to Xc with strikingly different ranges of specificity, suggesting that QDR to Xc involves a complex network integrating multiple response pathways triggered by distinct pathogen molecular determinants. (bvsalud.org)
Genes having at least one occurrence of the highly conserved motif M125 RAAGNYNNCTTY in the regions spanning 4 kb centered on their transcription starting sites [-2kb,+2kb]. (gsea-msigdb.org)

These sequences represent the protein coding region of the ASCL4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. (genscript.com)
Canis lupus familiaris achaete-scute family bHLH transcription factor 4 (ASCL4), mRNA. (genscript.com)

Waves of changes in the proteome in the fourth, seventh and eighth decades of life reflected distinct biological pathways and revealed differential associations with the genome and proteome of age-related diseases and phenotypic traits. (stanford.edu)

The overall results provide a systematic view of gene regulation in the human, which will be refined as additional mammalian genomes become available. (gsea-msigdb.org)

A genomic region found in DROSOPHILA . (bvsalud.org)
A nested genome-wide association mapping approach was used to finely map the genomic regions associated with QDR to Xcc12824 (race 2) and XccCFBP6943 (race 6). (bvsalud.org)

achaete-scute family bHLH transc. (gsea-msigdb.org)

Members of one of these receptor families, the olfactory receptors, form a complex with another protein, the olfactory coreceptor that is essential for both positioning and stabilizing the receptor, as well as the actual function. (elifesciences.org)

Here, we present a comparative analysis of the human, mouse, rat and dog genomes to create a systematic catalogue of common regulatory motifs in promoters and 3' untranslated regions (3' UTRs). (gsea-msigdb.org)

Comprehensive identification of all functional elements encoded in the human genome is a fundamental need in biomedical research. (gsea-msigdb.org)

Several eye-field transcription factors (EFTFs) are expressed in the anterior region of the vertebrate neural plate and are essential for eye formation. (biologists.com)

The demonstration of human achaete-scute homologue (HASH1) gene expression, although still investigational, could become the diagnostic procedure of choice. (medscape.com)
An achaete-scute homologue essential for neuroendocrine differentiation in the lung. (labome.org)
b>Mash1 , a mammalian homologue of the Drosophila proneural genes of the achaete-scute complex, is transiently expressed throughout the developing peripheral autonomic nervous system and in subsets of cells in the neural tube. (labome.org)

Proneural genes are conserved throughout the animal kingdom and fall into two main classes: the achaete-scute ( ac-sc ) and atonal ( ato ) gene families. (biomedcentral.com)
proteins, atonal and achaete-scute, have proneural activities in Drosophila, and the mouse achaete-scute homolog MASH1 is required for the differentiation of several neural lineages. (labome.org)

A genomic region found in DROSOPHILA . (nih.gov)
Drosophila imaginal discs provide an excellent model system to investigate how genetic information specifies the different body regions of an organism and how these regions are patterned. (silverchair.com)

1. Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer. (nih.gov)

By contrast, a second element (IroRE 1 ) mediates activation by both the EGFR and Dpp pathways, thus promoting expression of Iro-C in a region of elevated levels of Dpp signalling, the prospective lateral notum near the anterior-posterior compartment boundary. (silverchair.com)

Here, we review the highly complex processes contributing to NED. (biomedcentral.com)

Pseudoautosomal Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)

The regulatory influence of the APD is normally restricted to the animal pole region, but can operate in most cells of the embryo because, in the absence of Wnt and Nodal, the APD expands throughout the embryo. (biologists.com)

This is partially due to the ability to analyze cancer genomes on a whole genome basis. (medscape.com)
2. ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer. (nih.gov)
7. MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer. (nih.gov)
16. Comparative analysis of TTF-1 binding DNA regions in small-cell lung cancer and non-small-cell lung cancer. (nih.gov)

Due to the rare and complex nature of ENB, multiple opinions exist regarding the etiology, optimal staging system, and treatment modalities. (medscape.com)

This graph shows the total number of publications written about "Pseudoautosomal Regions" by people in this website by year, and whether "Pseudoautosomal Regions" was a major or minor topic of these publications. (umassmed.edu)
Below are the most recent publications written about "Pseudoautosomal Regions" by people in Profiles. (umassmed.edu)

These two regions pair regularly at male MEIOSIS and undergo RECOMBINATION. (umassmed.edu)

Interestingly, 20q is a region that has been implicated in other cancers, including breast, ovarian, and squamous cell carcinoma. (medscape.com)

Anatomy5

Organisms2

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes16

Disciplines and Occupations1

Information Science4

An arthropod cis-regulatory element functioning in sensory organ precursor development dates back to the Cambrian. (1/5)

Distribution and function of splash, an achaete-scute homolog in the adult olfactory organ of the Caribbean spiny lobster Panulirus argus. (2/5)

Expression of the active Notch1 decreases MTC tumor growth in vivo. (3/5)

Nematostella vectensis achaete-scute homolog NvashA regulates embryonic ectodermal neurogenesis and represents an ancient component of the metazoan neural specification pathway. (4/5)

BMP and Delta/Notch signaling control the development of amphioxus epidermal sensory neurons: insights into the evolution of the peripheral sensory system. (5/5)

Achaete-Scute Complex Genome Region

Basic Helix-Loop-Helix Transcription Factors

Genome

Sense Organs

Genome, Plant

Genome, Bacterial

Genome, Viral

Sequence Analysis, DNA

Genome, Human

Base Sequence

Genes, Insect

Chromosomes, Artificial, Bacterial

Chromosome Mapping

Molecular Sequence Data

Genomics

Drosophila

Nervous System

Drosophila Proteins

Chromosomes, Plant

Phylogeny

Contig Mapping

Evolution, Molecular

Genes, Plant

Herpesvirus 1, Gallid

Gene Components

Peripheral Nervous System

Encyclopedias as Topic

Helix-Loop-Helix Motifs

Gene Expression Regulation, Developmental

An arthropod cis-regulatory element functioning in sensory organ precursor development dates back to the Cambrian. (1/5)

Distribution and function of splash, an achaete-scute homolog in the adult olfactory organ of the Caribbean spiny lobster Panulirus argus. (2/5)

Expression of the active Notch1 decreases MTC tumor growth in vivo. (3/5)

Nematostella vectensis achaete-scute homolog NvashA regulates embryonic ectodermal neurogenesis and represents an ancient component of the metazoan neural specification pathway. (4/5)

BMP and Delta/Notch signaling control the development of amphioxus epidermal sensory neurons: insights into the evolution of the peripheral sensory system. (5/5)

BMP and Delta/Notch signaling control the development of amphioxus epidermal sensory neurons: insights into the evolution of...

Homology of Dipteran Bristles and Lepidopteran Scales: Requirement for the Bombyx mori achaete-scute Homologue ASH2 | Genetics

Achaete-scute homolog 4

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