Acetylserotonin O-Methyltransferase: An enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to N-acetylserotonin to form N-acetyl-5-methoxytryptamine (MELATONIN).DNA (Cytosine-5-)-Methyltransferase: An enzyme that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the 5-position of CYTOSINE residues in DNA.Methyltransferases: A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1.O(6)-Methylguanine-DNA Methyltransferase: An enzyme that transfers methyl groups from O(6)-methylguanine, and other methylated moieties of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single-step reaction. EC 2.1.1.63.Protein Methyltransferases: Enzymes that catalyze the methylation of amino acids after their incorporation into a polypeptide chain. S-Adenosyl-L-methionine acts as the methylating agent. EC 2.1.1.Methylation: Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)Histone-Lysine N-Methyltransferase: An enzyme that catalyzes the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine. EC 2.1.1.43.tRNA Methyltransferases: Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases within a transfer RNA molecule. EC 2.1.1.Protein-Arginine N-Methyltransferases: Enzymes that catalyze the methylation of arginine residues of proteins to yield N-mono- and N,N-dimethylarginine. This enzyme is found in many organs, primarily brain and spleen.S-Adenosylmethionine: Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)DNA-Cytosine Methylases: Methylases that are specific for CYTOSINE residues found on DNA.Protein D-Aspartate-L-Isoaspartate Methyltransferase: A PROTEIN O-METHYLTRANSFERASE that recognizes and catalyzes the methyl esterification of ISOASPARTIC ACID and D-ASPARTIC ACID residues in peptides and proteins. It initiates the repair of proteins damaged by the spontaneous decomposition of normal L-aspartic acid and L-asparagine residues.DNA Modification Methylases: Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms.Site-Specific DNA-Methyltransferase (Adenine-Specific): An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.DNA Methylation: Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.
(1/43) The structural basis of ordered substrate binding by serotonin N-acetyltransferase: enzyme complex at 1.8 A resolution with a bisubstrate analog.

Serotonin N-acetyltransferase, a member of the GNAT acetyltransferase superfamily, is the penultimate enzyme in the conversion of serotonin to melatonin, the circadian neurohormone. Comparison of the structures of the substrate-free enzyme and the complex with a bisubstrate analog, coenzyme A-S-acetyltryptamine, demonstrates that acetyl coenzyme A (AcCoA) binding is accompanied by a large conformational change that in turn leads to the formation of the serotonin-binding site. The structure of the complex also provides insight into how the enzyme may facilitate acetyl transfer. A water-filled channel leading from the active site to the surface provides a pathway for proton removal following amine deprotonation. Furthermore, structural and mutagenesis results indicate an important role for Tyr-168 in catalysis.  (+info)

(2/43) Melatonin, its precursors, and synthesizing enzyme activities in the human ovary.

The presence of melatonin (N-acetyl-5-methoxytryptamine) and its precursors, serotonin (5-hydroxytryptamine) and N-acetylserotonin, was demonstrated in extracts of human ovary using reverse-phase high-performance liquid chromatography coupled with fluorometric detection. In addition, activities of two melatonin-synthesizing enzymes, arylalkylamine N-acetyltransferase (NAT) and hydroxyindole-O-methyltransferase (HIOMT), were found in human ovary homogenates. The apparent Michaelis constants for the substrates of NAT and HIOMT in the human ovary were similar to those reported for the pineal glands of humans and other mammals. These findings strongly suggest that the human ovary, like the pineal gland, may synthesize melatonin from serotonin by the sequential action of NAT and HIOMT.  (+info)

(3/43) Genetic variability in plasma melatonin in sheep is due to pineal weight, not to variations in enzyme activities.

This study was conducted to determine the origin of the high variability in the mean nocturnal plasma melatonin concentration (MC) in sheep. Two extreme groups of 25 lambs each [low (L) and high (H)] were obtained by calculating their genetic value on the basis of the MC of their parents. The MC of lambs was significantly higher in the H group than in the L group (L: 189.7 +/- 24.4 vs. H: 344.1 +/- 33.0 pg/ml, P < 0.001). Within each group, 13 lambs were slaughtered during the day (D) and 12 lambs during the night (N). Pineal weight was significantly higher in the H group than in the L group (L: 83.5 +/- 6.7 vs. H: 119.1 +/- 9.2 mg, P < 0.01) but did not differ between D and N. The amount of melatonin released in vitro per milligram of pineal gland, the arylalkylamine N-acetyltransferase (AANAT) activity, the AANAT protein content, and the level of AANAT mRNA differed significantly between D and N but not with genetic group. Hydroxyindole O-methyltransferase activity did not differ significantly between D and N or between genetic groups. Therefore, the genetic difference in MC between the two groups of lambs was attributed to a difference in pineal size, not in enzymatic activity of the pinealocytes.  (+info)

(4/43) Identification of highly elevated levels of melatonin in bone marrow: its origin and significance.

Bone marrow is an important tissue in generation of immunocompetent and peripheral blood cells. The progenitors of hematopoietic cells in bone marrow exhibit continuous proliferation and differentiation and they are highly vulnerable to acute or chronic oxidative stress. In this investigation, highly elevated levels of the antioxidant melatonin were identified in rat bone marrow using immunocytochemistry, radioimmunoassay, high performance liquid chromatography with electrochemical detection and mass spectrometry. Night-time melatonin concentrations (expressed as pg melatonin/mg protein) in the bone marrow of rats were roughly two orders of magnitude higher than those in peripheral blood. Measurement of the activities of the two enzymes (N-acetyltransferase (NAT) and hydroxyindole-O-methoxyltransferase (HIOMT)) which synthesize melatonin from serotonin showed that bone marrow cells have measurable NAT activity, but they have very low levels of HIOMT activity (at the one time they were measured). From these studies we could not definitively determine whether melatonin was produced in bone marrow cells or elsewhere. To investigate the potential pineal origin of bone marrow melatonin, long-term (8-month) pinealectomized rats were used to ascertain if the pineal gland is the primary source of this antioxidant. The bone marrow of pinealectomized rats, however, still exhibited high levels of melatonin. These results indicate that a major portion of the bone marrow's melatonin is of extrapineal origin. Immunocytochemistry clearly showed a positive melatonin reaction intracellularly in bone marrow cells. A melatonin concentrating mechanism in these cells is suggested by these findings and this may involve a specific melatonin binding protein. Since melatonin is an endogenous free radical scavenger and an immune-enhancing agent, the high levels of melatonin in bone marrow cells may provide on-site protection to reduce oxidative damage to these highly vulnerable hematopoietic cells and may enhance the immune capacity of cells such as lymphocytes.  (+info)

(5/43) Regulation of hydroxyindole-O-methyltransferase gene expression in Japanese quail (Coturnix coturnix japonica).

Hydroxyindole-O-methyltrasferase (HIOMT) plays an important role as the final enzyme in the synthesis of melatonin. In this study, the expression of the HIOMT gene in Japanese quail was investigated with respect to tissue distribution and the effects of light and vitamin A deficiency. HIOMT mRNA in the pineal gland and eye had a clear daily rhythm with peak values in daytime. The testis also contained a detectable amount of HIOMT mRNA, which did not display a rhythmic change over a 24-h period. When birds were rendered vitamin A deficient through feeding with a vitamin A-free diet, the daily rhythm of the HIOMT gene almost disappeared in both the pineal gland and eye due to increases in the nighttime values. Our previous observations and these results suggest that vitamin A and a photo-signal are required to maintain the rhythmic expression of the HIOMT gene as well as the arylalkylamine N-acetyltransferase gene.  (+info)

(6/43) Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells.

We showed in human melanoma cells tryptophan hydroxylase (TPH) and hydroxyindole methyltransferase genes expression with the sequential enzymatic activities of TPH, serotonin (Ser) N-acetyltransferase and hydroxyindole methyltransferase. The presence of the products Ser, 5OH-tryptophan, N-acetylserotonin, melatonin (Mel), 5-methoxytryptamine and 5-methoxytryptophol was documented by liquid chromatography-mass spectrometry. Thus, human melanoma cells can synthesize and metabolize Ser and Mel.  (+info)

(7/43) Serotoninergic and melatoninergic systems are fully expressed in human skin.

We investigated the cutaneous expression of genes and enzymes responsible for the multistep conversion of tryptophan to serotonin and further to melatonin. Samples tested were human skin, normal and pathologic (basal cell carcinoma and melanoma), cultured normal epidermal and follicular melanocytes, melanoma cell lines, normal neonatal and adult epidermal and follicular keratinocytes, squamous cell carcinoma cells, and fibroblasts from dermis and follicular papilla. The majority of the samples showed simultaneous expression of the genes for tryptophan hydroxylase, arylalkylamine N-acetyltransferase (AANAT), and hydroxyindole-O-methyltransferase (HIOMT). The products of AANAT activity were identified by RP-HPLC with fluorimetric detection in human skin and in cultured normal and malignant melanocytes and immortalized keratinocytes; HIOMT activity was detected in human skin, keratinocytes, and melanoma cells. N-acetylserotonin (NAS) was detected by RP-HPLC in human skin extracts. NAS identity was confirmed further by LC/MS in keratinocytes. In conclusion, we provide evidence that the human skin expresses intrinsic serotonin and melatonin biosynthetic pathways.  (+info)

(8/43) Molecular cloning and nucleotide sequence of a cDNA encoding hydroxyindole O-methyltransferase from chicken pineal gland.

Hydroxyindole O-methyltransferase (EC 2.1.1.4) is the enzyme that catalyses the synthesis of melatonin in the pineal gland and in the retina. Polyadenylated RNA from chicken pineal glands was used to prepare a cDNA library in lambda gt11. The library was screened with an antiserum directed against chicken hydroxyindole O-methyltransferase, and one cDNA clone was isolated. The fusion protein expressed by phage lysogens was identified on Western blots as a 165 kDA immunoreactive protein (beta-galactosidase, 110 kDa; hydroxyindole O-methyltransferase, 38 kDa). The fusion protein exhibited hydroxyindole O-methyltransferase activity. Its Km values for N-acetyl-5-hydroxytryptamine and S-adenosylmethionine were 5 times those of the natural enzyme. The intrinsic activity of the fusion protein was approx. 0.25% that of the natural enzyme. The cDNA consisted of 1436 nucleotides, including a 1038-nucleotide sequence encoding a full-length 346-amino-acid hydroxyindole O-methyltransferase. Comparison with bovine hydroxyindole O-methyltransferase [Ishida, Obinata & Deguchi (1987) J. Biol. Chem. 262, 2895-2899] revealed 52% identity in nucleotide sequences and 44% identity in peptide sequences. Northern-blot analysis revealed the presence of hydroxyindole O-methyltransferase mRNA transcripts in chicken pineal gland and retina, but not in the telencephalon.  (+info)

*  Acetylserotonin O-methyltransferase
... (ASMT), Acetylserotonin N-methyltransferase, Acetylserotonin methyltransferase (Y ... Acetylserotonin O-methyltransferase The second reaction (Figure 4) catalyzed by N-Acetylserotonin O-methyltransferase in the ... Synonyms of N- Acetylserotonin O-methyltransferase are Hydroxyindole O-methyltransferase (HIOMT), ... suggests that Hydroxyindole O-methyltransferase (synonym for N- Acetylserotonin O-methyltransferase) plays a role in the human ...
*  N-acetylserotonin O-methyltransferase-like protein
... is an enzyme that in humans is encoded by the ASMTL gene. GRCh38: Ensembl ... "Entrez Gene: ASMTL acetylserotonin O-methyltransferase-like". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to ...
*  Y linkage
As of the year 2000, a number of genes were known to be Y-linked, including: ASMTY (acetylserotonin methyltransferase), TSPY ( ...
*  Pinealocyte
N-acetylserotonin is converted into melatonin by the enzyme hydroxyindole O-methyltransferase (HIOMT), also known as ... acetylserotonin O-methyltransferase (ASMT). Activity of these enzymes is high during the night and regulated by the mechanisms ... The serotonin is then acetylated by the AANAT enzyme and converted into N-acetylserotonin. ...
*  Aralkylamine N-acetyltransferase
N-acetylserotonin O-methyltransferase (ASMT) to generate melatonin. The N-acetyltransferase reaction has been suggested to be ... After the transfer of the acetyl group has occurred, the products are orderly released with N-acetyl-serotonin first and CoA ... In the biosynthesis of melatonin, N-acetylserotonin is further methylated by another enzyme, ... to produce N-acetylserotonin. Based on this mechanism, it might be expected that a bisubstrate analog inhibitor, derived from ...
*  N-Acetylserotonin
... and is converted to melatonin by acetylserotonin O-methyltransferase (ASMT). NAS is able to penetrate the blood-brain barrier, ... N-Acetylserotonin (NAS), also known as normelatonin, is a naturally occurring chemical precursor and intermediate in the ... 1999). "N-acetylserotonin is a better extra- and intracellular antioxidant than melatonin". FEBS Lett. 449 (2-3): 206-10. doi: ... February 2010). "N-acetylserotonin activates TrkB receptor in a circadian rhythm". Proceedings of the National Academy of ...
*  List of EC numbers (EC 2)
... thetin-homocysteine S-methyltransferase EC 2.1.1.4: acetylserotonin O-methyltransferase EC 2.1.1.5: betaine-homocysteine S- ... sterol 24-C-methyltransferase EC 2.1.1.42: luteolin O-methyltransferase EC 2.1.1.43: histone-lysine N-methyltransferase EC 2.1. ... methyltransferase EC 2.1.1.6: catechol O-methyltransferase EC 2.1.1.7: nicotinate N-methyltransferase EC 2.1.1.8: histamine N- ... phenol O-methyltransferase EC 2.1.1.26: iodophenol O-methyltransferase EC 2.1.1.27: tyramine N-methyltransferase EC 2.1.1.28: ...
*  List of MeSH codes (D08)
... acetylserotonin n-methyltransferase MeSH D08.811.913.555.500.175 --- betaine-homocysteine S-methyltransferase MeSH D08.811. ... histone-lysine n-methyltransferase MeSH D08.811.913.555.500.800.650 --- o-6-methylguanine-DNA methyltransferase MeSH D08.811. ... protein o-methyltransferase MeSH D08.811.913.555.500.800.800.700 --- protein d-aspartate-l-isoaspartate methyltransferase MeSH ... site-specific dna-methyltransferase (adenine-specific) MeSH D08.811.913.555.500.350.850 --- site-specific dna methyltransferase ...
*  O-methyltransferase
Examples are : Acetylserotonin O-methyltransferase Apigenin 4'-O-methyltransferase Caffeate O-methyltransferase Caffeoyl-CoA O- ... O-methyltransferase Kaempferol 4'-O-methyltransferase Licodione 2'-O-methyltransferase Loganate O-methyltransferase Luteolin O- ... O-methyltransferase Phenol O-methyltransferase Polysaccharide O-methyltransferase Protein-glutamate O-methyltransferase Protein ... methyltransferase Catechol O-methyltransferase Chlorophenol O-methyltransferase Columbamine O-methyltransferase ...
*  Melatonin
Hydroxyindole O-methyltransferase and S-adenosyl methionine convert N-acetylserotonin into melatonin through methylation of the ... N-acetylserotonin is methylated at the hydroxyl position by S-adenosyl methionine (SAM) to produce S-adenosyl homocysteine (SAH ... The thiol from coenzyme A serves as a good leaving group when attacked by a general base to give N-acetylserotonin. ... Donohue SJ, Roseboom PH, Illnerova H, Weller JL, Klein DC (1993). "Human hydroxyindole-O-methyltransferase: presence of LINE-1 ...
*  Harmaline
... is known to act as a histamine N-methyltransferase inhibitor. This explains how harmaline elicits its wakefulness- ... Harmaline forces the anabolic metabolism of serotonin into normelatonin or n-acetylserotonin, and then to melatonin, the body's ... Cumming, P; Vincent SR (September 1992). "Inhibition of histamine-N-methyltransferase (HNMT) by fragments of 9-amino-1,2,3,4- ...
acetylserotonin O-methyltransferase like ELISA Kits | Biocompare.com  acetylserotonin O-methyltransferase like ELISA Kits | Biocompare.com
Compare acetylserotonin O-methyltransferase like ELISA Kits from leading suppliers on Biocompare. View specifications, prices, ... acetylserotonin O-methyltransferase like ELISA Kits. The ELISA (enzyme-linked immunosorbent assay) is a well-established ... Your search returned 23 acetylserotonin O-methyltransferase like ELISA ELISA Kit across 2 suppliers. ...
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Hydroxyindole-O-methyltransferase: Acetylserotonin O-methyltransferase  Hydroxyindole-O-methyltransferase: Acetylserotonin O-methyltransferase
GoPubMed lists recent and important papers and reviews for acetylserotonin O-methyltransferase(hydroxyindole-O- ... The N-acetylserotonin O-methyltransferase (ASMT) gene encodes the enzyme that catalyzes the conversion of N-acetylserotonin to ... Cloning and functional characterization of the Arabidopsis N-acetylserotonin O-methyltransferase responsible for melatonin ... and N-acetylserotonin-O-methyltransferase (ASMT) was analyzed by RT-PCR, q-PCR and Western-blot in ram testes, epididymis, and ...
more infohttps://www.gopubmed.org/hydroxyindole-o-methyltransferase.html
Acetylserotonin O-methyltransferase - Wikipedia  Acetylserotonin O-methyltransferase - Wikipedia
Acetylserotonin O-methyltransferase (ASMT), Acetylserotonin N-methyltransferase, Acetylserotonin methyltransferase (Y ... Acetylserotonin O-methyltransferase The second reaction (Figure 4) catalyzed by N-Acetylserotonin O-methyltransferase in the ... Synonyms of N- Acetylserotonin O-methyltransferase are Hydroxyindole O-methyltransferase (HIOMT), ... suggests that Hydroxyindole O-methyltransferase (synonym for N- Acetylserotonin O-methyltransferase) plays a role in the human ...
more infohttps://en.wikipedia.org/wiki/Acetylserotonin_O-methyltransferase
N-acetylserotonin O-methyltransferase-like protein - Wikipedia  N-acetylserotonin O-methyltransferase-like protein - Wikipedia
N-acetylserotonin O-methyltransferase-like protein is an enzyme that in humans is encoded by the ASMTL gene. GRCh38: Ensembl ... "Entrez Gene: ASMTL acetylserotonin O-methyltransferase-like". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to ...
more infohttps://en.wikipedia.org/wiki/N-acetylserotonin_O-methyltransferase-like_protein
Acetylserotonin O-methyltransferase elisa and antibody  Acetylserotonin O-methyltransferase elisa and antibody
Recombinant Protein and Acetylserotonin O-methyltransferase Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and ... Acetylserotonin O-methyltransferase 1. Acetylserotonin O-methyltransferase 1 ELISA Kit. Acetylserotonin O-methyltransferase 1 ... Acetylserotonin O-methyltransferase 2. Acetylserotonin O-methyltransferase 2 ELISA Kit. Acetylserotonin O-methyltransferase 2 ... Acetylserotonin O-methyltransferase 3. Acetylserotonin O-methyltransferase 3 ELISA Kit. Acetylserotonin O-methyltransferase 3 ...
more infohttps://www.mybiosource.com/proteins-family/acetylserotonin-o-methyltransferase
N-acetylserotonin O-methyltransferase-like protein  N-acetylserotonin O-methyltransferase-like protein
... while the C-terminus is similar to N-acetylserotonin O-methyltransferase. This gene is located in the pseudoautosomal region 1 ... The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity. The ...
more infohttps://pharos.nih.gov/idg/targets/ASMTL
O-methyltransferase COMT-type (IPR016461) | InterPro | EMBL-EBI  O-methyltransferase COMT-type (IPR016461) | InterPro | EMBL-EBI
... isoflavone-7-O-methyltransferase (EC:2.1.1.150), inositol 4-methyltransferase (EC:2.1.1.129) and acetylserotonin O- ... O-methyltransferase COMT-type (IPR016461). Short name: O-MeTrfase_COMT Family relationships *O-methyltransferase COMT-type ( ... Molecular cloning of a plant N-acetylserotonin methyltransferase and its expression characteristics in rice.. J. Pineal Res. 50 ... This entry represents a family of O-methyltransferases (O-MTases) that includes caffeic acid O-methyltransferase (COMT) (EC:2.1 ...
more infohttp://www.ebi.ac.uk/interpro/entry/IPR016461
Browse our ASMT ELISA Kits  Browse our ASMT ELISA Kits
acetylserotonin O-methyltransferase , hydroxyindole O-methyltransferase , hydroxyindole-O-methyltransferase , acetylserotonin N ... methyltransferase , acetylserotonin methyltransferase (Y chromosome) , HIOMT , acetylserotonin methyltransferase , ... Acetylserotonin O-Methyltransferase (ASMT) ELISA Kits. ASMT belongs to the methyltransferase superfamily, and is located in the ... Cow (Bovine) Acetylserotonin O-Methyltransferase (ASMT) interaction partners * The study revealed that ASMT and MTNR1A (show ...
more infohttps://www.antibodies-online.com/abstract/Acetylserotonin+O-Methyltransferase+
Frontiers | Melatonin Regulates Root Meristem by Repressing Auxin Synthesis and Polar Auxin Transport in Arabidopsis | Plant...  Frontiers | Melatonin Regulates Root Meristem by Repressing Auxin Synthesis and Polar Auxin Transport in Arabidopsis | Plant...
... and N-acetylserotonin O-methyltransferase (ASMT)] (Kang et al., 2007a,b, 2011, 2013; Okazaki et al., 2009; Fujiwara et al., ... Recent studies found that N-acetylserotonin can also be synthesized via caffeic acid O-methyltransferase (COMT) in Arabidopsis ... Caffeic acid O-methyltransferase is involved in the synthesis of melatonin by methylating N-acetylserotonin in Arabidopsis. J. ... Molecular cloning of a plant N-acetylserotonin methyltransferase and its expression characteristics in rice. J. Pineal Res. 50 ...
more infohttps://www.frontiersin.org/articles/10.3389/fpls.2016.01882/full
Frontiers | Comparative Transcriptional Profiling of Melatonin Synthesis and Catabolic Genes Indicates the Possible Role of...  Frontiers | Comparative Transcriptional Profiling of Melatonin Synthesis and Catabolic Genes Indicates the Possible Role of...
Molecular cloning of a plant N-acetylserotonin methyltransferase and its expression characteristics in rice. J. Pineal Res. 50 ... temperatures and under dark conditions due to increased serotonin N-acetyltransferase and N-acetylserotonin methyltransferase ... and N-aceylserotonin O-methyltransferase (ASMT) (Arnao and Hernández-Ruiz, 2014, 2015; Zuo et al., 2014). Thereafter, melatonin ... N-aceylserotonin methyltransferase; AXR3, Auxin Resistant 3; BL, indole-3-acetic acid; DAT, days after transplanting; GA, ...
more infohttps://www.frontiersin.org/articles/10.3389/fpls.2016.00676/full
Molecules | Free Full-Text | Melatonin Treatment Reduces Oxidative Damage and Normalizes Plasma Pro-Inflammatory Cytokines in...  Molecules | Free Full-Text | Melatonin Treatment Reduces Oxidative Damage and Normalizes Plasma Pro-Inflammatory Cytokines in...
A Comparative Genomic and Transcriptomic Survey Provides Novel Insights into N-Acetylserotonin Methyltransferase (ASMT) in Fish ...
more infohttps://www.mdpi.com/1420-3049/22/10/1728
Molecules  | Free Full-Text | Melatonin Treatment Reduces Oxidative Damage and Normalizes Plasma Pro-Inflammatory Cytokines in...  Molecules | Free Full-Text | Melatonin Treatment Reduces Oxidative Damage and Normalizes Plasma Pro-Inflammatory Cytokines in...
A Comparative Genomic and Transcriptomic Survey Provides Novel Insights into N-Acetylserotonin Methyltransferase (ASMT) in Fish ...
more infohttp://www.mdpi.com/1420-3049/22/10/1728/htm
Homeobox Genes and Melatonin Synthesis: Regulatory Roles of the Cone-Rod Homeobox Transcription Factor in the Rodent Pineal...  Homeobox Genes and Melatonin Synthesis: Regulatory Roles of the Cone-Rod Homeobox Transcription Factor in the Rodent Pineal...
The enzymes AANAT and acetylserotonin O-methyltransferase (ASMT) catalyze the conversion of serotonin to melatonin. Nocturnal ... J. Shen, K. Ghai, P. Sompol et al., "N-acetyl serotonin derivatives as potent neuroprotectants for retinas," Proceedings of the ... M. Bernard, V. Dinet, and P. Voisin, "Transcriptional regulation of the chicken hydroxyindole-O-methyltransferase gene by the ... D. C. Klein and R. Y. Moore, "Pineal N-acetyltransferase and hydroxyindole-O-methyltransferase: control by the ...
more infohttps://www.hindawi.com/journals/bmri/2014/946075/
Melatonin Uses, Benefits & Dosage - Drugs.com Herbal Database  Melatonin Uses, Benefits & Dosage - Drugs.com Herbal Database
... also known as acetylserotonin methyltransferase), into melatonin. 9 The suprachiasmatic nucleus of the anterior hypothalamus is ... results suggesting that patients with ASD have low melatonin levels owing to a deficit in the acetylserotonin methyltransferase ...
more infohttps://www.drugs.com/npp/melatonin.html
ASMT - PCR Primer Pair - Probe | PrimePCR | Bio-Rad  ASMT - PCR Primer Pair - Probe | PrimePCR | Bio-Rad
Acetylserotonin O-methyltransferase. Aliases:. Not Available. RefSeq:. Not Available. Ensembl:. ENSCAFG00000024670 Entrez:. 0 ...
more infohttp://www.bio-rad.com/en-us/prime-pcr-assays/assay/qcfacip0011093-primepcr-probe-assay-asmt-dog
ASMTL (Human) Recombinant Protein (P01) - (H00008623-P01) - Products - Abnova  ASMTL (Human) Recombinant Protein (P01) - (H00008623-P01) - Products - Abnova
OTTHUMP00000022825,acetylserotonin N-methyltransferase-like. *Related Product. *H00008623-B01P. * ASMTL purified MaxPab mouse ...
more infohttp://www.abnova.com/products/products_detail.asp?catalog_id=H00008623-P01
KEGG BRITE: Enzymes - Pseudomonas putida H8234  KEGG BRITE: Enzymes - Pseudomonas putida H8234
2.1.1.4 acetylserotonin O-methyltransferase 2.1.1.5 betaine---homocysteine S-methyltransferase 2.1.1.6 catechol O- ... 2.1.1.248 methylamine---corrinoid protein Co-methyltransferase 2.1.1.249 dimethylamine---corrinoid protein Co-methyltransferase ... glutamate N-methyltransferase subunit A [EC:2.1.1.21] K22082 mgsB; methylamine---glutamate N-methyltransferase subunit B [EC: ... glutamate N-methyltransferase subunit C [EC:2.1.1.21] K22083 mgsC; methylamine---glutamate N-methyltransferase subunit C [EC: ...
more infohttps://www.kegg.jp/kegg-bin/get_htext?pput01000+L483_19180
KEGG BRITE: Enzymes - Sinocyclocheilus anshuiensis  KEGG BRITE: Enzymes - Sinocyclocheilus anshuiensis
2.1.1.4 acetylserotonin O-methyltransferase 2.1.1.5 betaine---homocysteine S-methyltransferase 2.1.1.6 catechol O- ... 107676944 histone-lysine N-methyltransferase 107655195 histone-lysine N-methyltransferase 107655184 N-lysine methyltransferase ... 2.1.1.43 histone-lysine N-methyltransferase 107693346 histone-lysine N-methyltransferase ASH1L-like isoform X1 107656475 ... 107657332 N-lysine methyltransferase KMT5A-A-like 107704173 N-lysine methyltransferase KMT5A-A-like 107693405 kmt5a; N-lysine ...
more infohttps://www.kegg.jp/kegg-bin/get_htext?sanh01000+107694947
Search results for: Bacillus cereus  Search results for: 'Bacillus cereus'
Protein Name:N-acetylserotonin O-methyltransferase-like protein Catalog #:OAAN02096 Type: pAb ...
more infohttps://www.avivasysbio.com/en/catalogsearch/result/?q=Bacillus%20cereus
  • Even within the structurally conserved family of Class I methyltransferases, a wide variety of mechanisms have evolved to activate the catalytic nucleophile, dependent on the polarizability of the target atom [ PMID: 12826405 ]. (ebi.ac.uk)