Acetylesterase: An enzyme that catalyzes the conversion of acetate esters and water to alcohols and acetate. EC 3.1.1.6.Triacetin: A triglyceride that is used as an antifungal agent.Shigella flexneri: A bacterium which is one of the etiologic agents of bacillary dysentery (DYSENTERY, BACILLARY) and sometimes of infantile gastroenteritis.EsterasesTriolein: (Z)-9-Octadecenoic acid 1,2,3-propanetriyl ester.Shigella: A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that ferments sugar without gas production. Its organisms are intestinal pathogens of man and other primates and cause bacillary dysentery (DYSENTERY, BACILLARY).beta-Galactosidase: A group of enzymes that catalyzes the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-galactosides. Deficiency of beta-Galactosidase A1 may cause GANGLIOSIDOSIS, GM1.Cholesterol Esters: Fatty acid esters of cholesterol which constitute about two-thirds of the cholesterol in the plasma. The accumulation of cholesterol esters in the arterial intima is a characteristic feature of atherosclerosis.EstersDysentery, Bacillary: DYSENTERY caused by gram-negative rod-shaped enteric bacteria (ENTEROBACTERIACEAE), most often by the genus SHIGELLA. Shigella dysentery, Shigellosis, is classified into subgroups according to syndrome severity and the infectious species. Group A: SHIGELLA DYSENTERIAE (severest); Group B: SHIGELLA FLEXNERI; Group C: SHIGELLA BOYDII; and Group D: SHIGELLA SONNEI (mildest).Carboxylic Ester Hydrolases: Enzymes which catalyze the hydrolysis of carboxylic acid esters with the formation of an alcohol and a carboxylic acid anion.Plant Mucilage: A type of viscous polysaccharide that is secreted from PLANTS. It has natural properties that are useful in the formulation of ADHESIVES.Pectins: High molecular weight polysaccharides present in the cell walls of all plants. Pectins cement cell walls together. They are used as emulsifiers and stabilizers in the food industry. They have been tried for a variety of therapeutic uses including as antidiarrheals, where they are now generally considered ineffective, and in the treatment of hypercholesterolemia.Influenzavirus C: A genus of the family ORTHOMYXOVIRIDAE comprising viruses similar to types A and B but less common, more stable, more homogeneous, and lacking the neuraminidase protein. They have not been associated with epidemics but may cause mild influenza. Influenza C virus is the type species.Plants, Genetically Modified: PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.Plant Proteins: Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Bacteroidetes: A phylum of bacteria comprised of three classes: Bacteroides, Flavobacteria, and Sphingobacteria.Forsythia: A plant genus of the family OLEACEAE. Members contain suspensaside.Sialic Acids: A group of naturally occurring N-and O-acyl derivatives of the deoxyamino sugar neuraminic acid. They are ubiquitously distributed in many tissues.Treponema denticola: A species of bacteria in the family SPIROCHAETACEAE, frequently isolated from periodontal pockets (PERIODONTAL POCKET).N-Acetylneuraminic Acid: An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)Bacteroides: A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.Prevotella intermedia: A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium is a common commensal in the gingival crevice and is often isolated from cases of gingivitis and other purulent lesions related to the mouth.Porphyromonas gingivalis: A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)Epoxide Hydrolases: Enzymes that catalyze reversibly the formation of an epoxide or arene oxide from a glycol or aromatic diol, respectively.Hydrolysis: The process of cleaving a chemical compound by the addition of a molecule of water.Human Body: The human being as a non-anatomical and non-zoological entity. The emphasis is on the philosophical or artistic treatment of the human being, and includes lay and social attitudes toward the body in history. (From J. Cassedy, NLM History of Medicine Division)Naphthol AS D Esterase: Hydrolytic enzyme activity used as a histocytochemical test for the presence of esterases in tissue. Substrate used is 3-hydroxy-4'-nitro-2-naphthanilide chloroacetate (naphthol AS-D).Sterol Esterase: An enzyme that catalyzes the hydrolysis of CHOLESTEROL ESTERS and some other sterol esters, to liberate cholesterol plus a fatty acid anion.Alcohol Drinking: Behaviors associated with the ingesting of alcoholic beverages, including social drinking.Water: A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Cellulase: An endocellulase with specificity for the hydrolysis of 1,4-beta-glucosidic linkages in CELLULOSE, lichenin, and cereal beta-glucans.Cellulases: A family of glycosidases that hydrolyse crystalline CELLULOSE into soluble sugar molecules. Within this family there are a variety of enzyme subtypes with differing substrate specificities that must work together to bring about complete cellulose hydrolysis. They are found in structures called CELLULOSOMES.Cellulose: A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.Neurospora crassa: A species of ascomycetous fungi of the family Sordariaceae, order SORDARIALES, much used in biochemical, genetic, and physiologic studies.Neurospora: A genus of ascomycetous fungi, family Sordariaceae, order SORDARIALES, comprising bread molds. They are capable of converting tryptophan to nicotinic acid and are used extensively in genetic and enzyme research. (Dorland, 27th ed)Receptor-Like Protein Tyrosine Phosphatases: A subcategory of protein tyrosine phosphatases that are bound to the cell membrane. They contain cytoplasmic tyrosine phosphatase domains and extracellular protein domains that may play a role in cell-cell interactions by interacting with EXTRACELLULAR MATRIX components. They are considered receptor-like proteins in that they appear to lack specific ligands.Biofuels: Hydrocarbon-rich byproducts from the non-fossilized BIOMASS that are combusted to generate energy as opposed to fossilized hydrocarbon deposits (FOSSIL FUELS).Cellulose 1,4-beta-Cellobiosidase: An exocellulase with specificity for the hydrolysis of 1,4-beta-D-glucosidic linkages in CELLULOSE and cellotetraose. It catalyzes the hydrolysis of terminal non-reducing ends of beta-D-glucosides with release of CELLOBIOSE.beta-Glucosidase: An exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of GLUCOSE.Lignin: The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed)Allergy and Immunology: A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder.Access to Information: Individual's rights to obtain and use information collected or generated by others.Immunotherapy: Manipulation of the host's immune system in treatment of disease. It includes both active and passive immunization as well as immunosuppressive therapy to prevent graft rejection.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Gangliosides: A subclass of ACIDIC GLYCOSPHINGOLIPIDS. They contain one or more sialic acid (N-ACETYLNEURAMINIC ACID) residues. Using the Svennerholm system of abbrevations, gangliosides are designated G for ganglioside, plus subscript M, D, or T for mono-, di-, or trisialo, respectively, the subscript letter being followed by a subscript arabic numeral to indicated sequence of migration in thin-layer chromatograms. (From Oxford Dictionary of Biochemistry and Molecular Biology, 1997)Immune System Diseases: Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Peer Review, Research: The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.G(M1) Ganglioside: A specific monosialoganglioside that accumulates abnormally within the nervous system due to a deficiency of GM1-b-galactosidase, resulting in GM1 gangliosidosis.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Antibody Specificity: The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Epitopes: Sites on an antigen that interact with specific antibodies.Hybridomas: Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.Enzyme Assays: Methods used to measure the relative activity of a specific enzyme or its concentration in solution. Typically an enzyme substrate is added to a buffer solution containing enzyme and the rate of conversion of substrate to product is measured under controlled conditions. Many classical enzymatic assay methods involve the use of synthetic colorimetric substrates and measuring the reaction rates using a spectrophotometer.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).

Purification and characterization of an acetyl xylan esterase from Bacillus pumilus. (1/152)

Bacillus pumilus PS213 was found to be able to release acetate from acetylated xylan. The enzyme catalyzing this reaction has been purified to homogeneity and characterized. The enzyme was secreted, and its production was induced by corncob powder and xylan. Its molecular mass, as determined by gel filtration, is 190 kDa, while sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed a single band of 40 kDa. The isoelectric point was found to be 4.8, and the enzyme activity was optimal at 55 degrees C and pH 8.0. The activity was inhibited by most of the metal ions, while no enhancement was observed. The Michaelis contant (Km) and Vmax for alpha-naphthyl acetate were 1.54 mM and 360 micromol min-1 mg of protein-1, respectively.  (+info)

The hemagglutinin-esterase of mouse hepatitis virus strain S is a sialate-4-O-acetylesterase. (2/152)

By comparative analysis of the hemagglutinin-esterase (HE) protein of mouse hepatitis virus strain S (MHV-S) and the HE protein of influenza C virus, we found major differences in substrate specificities. In striking contrast to the influenza C virus enzyme, the MHV-S esterase was unable to release acetate from bovine submandibulary gland mucin. Furthermore, MHV-S could not remove influenza C virus receptors from erythrocytes. Analysis with free sialic acid derivatives revealed that the MHV-S HE protein specifically de-O-acetylates 5-N-acetyl-4-O-acetyl sialic acid (Neu4, 5Ac2) but not 5-N-acetyl-9-O-acetyl sialic acid (Neu5,9Ac2), which is the major substrate for esterases of influenza C virus and bovine coronaviruses. In addition, the MHV-S esterase converted glycosidically bound Neu4,5Ac2 of guinea pig serum glycoproteins to Neu5Ac. By expression of the MHV esterase with recombinant vaccinia virus and incubation with guinea pig serum, we demonstrated that the viral HE possesses sialate-4-O-acetylesterase activity. In addition to observed enzymatic activity, MHV-S exhibited affinity to guinea pig and horse serum glycoproteins. Binding required sialate-4-O-acetyl groups and was abolished by chemical de-O-acetylation. Since Neu4,5Ac2 has not been identified in mice, the nature of potential substrates and/or secondary receptors for MHV-S in the natural host remains to be determined. The esterase of MHV-S is the first example of a viral enzyme with high specificity and affinity toward 4-O-acetylated sialic acids.  (+info)

Lysosomal and cytosolic sialic acid 9-O-acetylesterase activities can Be encoded by one gene via differential usage of a signal peptide-encoding exon at the N terminus. (3/152)

9-O-Acetylation is one of the most common modifications of sialic acids, and it can affect several sialic acid-mediated recognition phenomena. We previously reported a cDNA encoding a lysosomal sialic acid-specific 9-O-acetylesterase, which traverses the endoplasmic reticulum-Golgi pathway and localizes primarily to lysosomes and endosomes. In this study, we report a variant cDNA derived from the same gene that contains a different 5' region. This cDNA has a putative open reading frame lacking a signal peptide-encoding sequence and is thus a candidate for the previously described cytosolic sialic acid 9-O-acetylesterase activity. Epitope-tagged constructs confirm that the new sequence causes the protein product to be targeted to the cytosol and has esterase activity. Using reverse transcription-polymerase chain reaction to distinguish the two forms of message, we show that although the lysosomal sialic acid-specific 9-O-acetylesterase message has a widespread pattern of expression in adult mouse tissues, this cytosolic sialic acid 9-O-acetylesterase form has a rather restricted distribution, with the strongest expression in the liver, ovary, and brain. Using a polyclonal antibody directed against the 69-amino acid region common to both proteins, we confirmed that the expression of glycosylated and nonglycosylated polypeptides occurred in appropriate subcellular fractions of normal mouse tissues. Rodent liver polypeptides reacting to the antibody also co-purify with previously described lysosomal sialic acid esterase activity and at least a portion of the cytosolic activity. Thus, two sialic acid 9-O-acetylesterases found in very different subcellular compartments can be encoded by a single gene by differential usage of a signal peptide-encoding exon at the N terminus. The 5'-rapid amplification of cDNA ends results and the differences in tissue-specific expression suggest that expression of these two products may be differentially regulated by independent promoters.  (+info)

Characterization of an acetyl xylan esterase from the anaerobic fungus Orpinomyces sp. strain PC-2. (4/152)

A 1,067-bp cDNA, designated axeA, coding for an acetyl xylan esterase (AxeA) was cloned from the anaerobic rumen fungus Orpinomyces sp. strain PC-2. The gene had an open reading frame of 939 bp encoding a polypeptide of 313 amino acid residues with a calculated mass of 34,845 Da. An active esterase using the original start codon of the cDNA was synthesized in Escherichia coli. Two active forms of the esterase were purified from recombinant E. coli cultures. The size difference of 8 amino acids was a result of cleavages at two different sites within the signal peptide. The enzyme released acetate from several acetylated substrates, including acetylated xylan. The activity toward acetylated xylan was tripled in the presence of recombinant xylanase A from the same fungus. Using p-nitrophenyl acetate as a substrate, the enzyme had a K(m) of 0.9 mM and a V(max) of 785 micromol min(-1) mg(-1). It had temperature and pH optima of 30 degrees C and 9.0, respectively. AxeA had 56% amino acid identity with BnaA, an acetyl xylan esterase of Neocallimastix patriciarum, but the Orpinomyces AxeA was devoid of a noncatalytic repeated peptide domain (NCRPD) found at the carboxy terminus of the Neocallimastix BnaA. The NCRPD found in many glycosyl hydrolases and esterases of anaerobic fungi has been postulated to function as a docking domain for cellulase-hemicellulase complexes, similar to the dockerin of the cellulosome of Clostridium thermocellum. The difference in domain structures indicated that the two highly similar esterases of Orpinomyces and Neocallimastix may be differently located, the former being a free enzyme and the latter being a component of a cellulase-hemicellulase complex. Sequence data indicate that AxeA and BnaA might represent a new family of hydrolases.  (+info)

Acetylation: a regulatory modification to rival phosphorylation? (5/152)

The fact that histones are modified by acetylation has been known for almost 30 years. The recent identification of enzymes that regulate histone acetylation has revealed a broader use of this modification than was suspected previously. Acetylases are now known to modify a variety of proteins, including transcription factors, nuclear import factors and alpha-tubulin. Acetylation regulates many diverse functions, including DNA recognition, protein-protein interaction and protein stability. There is even a conserved structure, the bromodomain, that recognizes acetylated residues and may serve as a signalling domain. If you think all this sounds familiar, it should be. These are features characteristic of kinases. So, is acetylation a modification analogous to phosphorylation? This review sets out what we know about the broader substrate specificity and regulation of acetyl- ases and goes on to compare acetylation with the process of phosphorylation.  (+info)

Rhamnogalacturonan acetylesterase elucidates the structure and function of a new family of hydrolases. (6/152)

BACKGROUND: The complex polysaccharide rhamnogalacturonan constitutes a major part of the hairy region of pectin. It can have different types of carbohydrate sidechains attached to the rhamnose residues in the backbone of alternating rhamnose and galacturonic acid residues; the galacturonic acid residues can be methylated or acetylated. Aspergillus aculeatus produces enzymes that are able to perform a synergistic degradation of rhamnogalacturonan. The deacetylation of the backbone by rhamnogalacturonan acetylesterase (RGAE) is an essential prerequisite for the subsequent action of the enzymes that cleave the glycosidic bonds. RESULTS: The structure of RGAE has been determined at 1.55 A resolution. RGAE folds into an alpha/beta/alpha structure. The active site of RGAE is an open cleft containing a serine-histidine-aspartic acid catalytic triad. The position of the three residues relative to the central parallel beta sheet and the lack of the nucleophilic elbow motif found in structures possessing the alpha/beta hydrolase fold show that RGAE does not belong to the alpha/beta hydrolase family. CONCLUSIONS: Structural and sequence comparisons have revealed that, despite very low sequence similarities, RGAE is related to seven other proteins. They are all members of a new hydrolase family, the SGNH-hydrolase family, which includes the carbohydrate esterase family 12 as a distinct subfamily. The SGNH-hydrolase family is characterised by having four conserved blocks of residues, each with one completely conserved residue; serine, glycine, asparagine and histidine, respectively. Each of the four residues plays a role in the catalytic function.  (+info)

Three multidomain esterases from the cellulolytic rumen anaerobe Ruminococcus flavefaciens 17 that carry divergent dockerin sequences. (7/152)

Three enzymes carrying esterase domains have been identified in the rumen cellulolytic anaerobe Ruminococcus flavefaciens 17. The newly characterized CesA gene product (768 amino acids) includes an N-terminal acetylesterase domain and an unidentified C-terminal domain, while the previously characterized XynB enzyme (781 amino acids) includes an internal acetylesterase domain in addition to its N-terminal xylanase catalytic domain. A third gene, xynE, is predicted to encode a multidomain enzyme of 792 amino acids including a family 11 xylanase domain and a C-terminal esterase domain. The esterase domains from CesA and XynB share significant sequence identity (44%) and belong to carbohydrate esterase family 3; both domains are shown here to be capable of deacetylating acetylated xylans, but no evidence was found for ferulic acid esterase activity. The esterase domain of XynE, however, shares 42% amino acid identity with a family 1 phenolic acid esterase domain identified from Clostridum thermocellum XynZ. XynB, XynE and CesA all contain dockerin-like regions in addition to their catalytic domains, suggesting that these enzymes form part of a cellulosome-like multienzyme complex. The dockerin sequences of CesA and XynE differ significantly from those previously described in R. flavefaciens polysaccharidases, including XynB, suggesting that they might represent distinct dockerin specificities.  (+info)

The acetyl xylan esterase of Bacillus pumilus belongs to a family of esterases with broad substrate specificity. (8/152)

The Bacillus pumilus gene encoding acetyl xylan esterase (axe) was identified and characterized. The axe gene was expressed and the recombinant enzyme produced in Escherichia coli was purified and characterized. The recombinant enzyme displayed similar properties to the acetyl xylan esterase (AXE) purified from B. pumilus. The AXE primary structure was 76% identical to the cephalosporin C deacetylase of B. subtilis, and 40% to two recently identified AXEs from Thermoanaerobacterium and Thermotoga maritima. These four proteins are of similar size and represent a new family of esterases having a broad substrate specificity. The recombinant AXE was demonstrated to have activity on several acetylated substrates, including on cephalosporin C.  (+info)

*Haemagglutinin-esterase fusion glycoprotein

... thioesterase I and rhamnogalacturonan acetylesterase. The haemagglutinin-esterase glycoprotein HEF must be cleaved by the ...

*Acetylesterase

In enzymology, an acetylesterase (EC 3.1.1.6) is an enzyme that catalyzes the chemical reaction an acetic ester + H2O ⇌ {\ ... Jansen EF; Nutting M-DF; Balls AK (1948). "The reversible inhibition of acetylesterase by diisopropyl fluorophosphate and ... and Citrus acetylesterase. As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes ...

*Rhamnogalacturonan acetylesterase

... (EC 3.1.1.86, RGAE) is an enzyme with systematic name rhamnogalacturonan 2/3-O-acetyl-alpha-D ... Rhamnogalacturonan acetylesterase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ... Molgaard, A.; Kauppinen, S.; Larsen, S. (2000). "Rhamnogalacturonan acetylesterase elucidates the structure and function of a ... "Molecular cloning and characterization of a rhamnogalacturonan acetylesterase from Aspergillus aculeatus. Synergism between ...

*Sialic acid acetylesterase

... (SIAE) is an enzyme that produces 9-O acetylated sialic acid e.g. in mammals. It down-regulates B ... 8 July 2010). "Functionally defective germline variants of sialic acid acetylesterase in autoimmunity". Nature. 466 (7303): 243 ...

*Sialate O-acetylesterase

... (SIAE) is a protein that in human is encoded by the SIAE gene located on chromosome 11. The SIAE ... In enzymology, a sialate O-acetylesterase (EC 3.1.1.53) is an enzyme that catalyzes the chemical reaction N-acetyl-O- ... 2004). "A Gene Encoding Sialic-Acid-Specific 9-O-Acetylesterase Found in Human Adult Testis". J. Biomed. Biotechnol. 2004 (3): ... 2014). "A missense single-nucleotide polymorphism in the sialic acid acetylesterase (SIAE) gene is associated with anti-PIT-1 ...

*Thermotoga hypogea

"Investigation of β-xylosidase, α-L-arabinofuranosidase and acetylesterase from Thermotoga hypogea." (2008). Dworkin, Martin, ...

*Acetylajmaline esterase

Polz, L.; Schübel, H.; Stöckigt, J. (1987). "Characterization of 2β(R)-17-O-acetylajmalan:acetylesterase-a specific enzyme ... Acetylajmaline esterase (EC 3.1.1.80, AAE, 2beta(R)-17-O-acetylajmalan:acetylesterase, acetylajmalan esterase) is an enzyme ...

*Tabersonine 16-O-methyltransferase

11-O-demethyl-17-O-deacetylvindoline 11-O-methylase and unspecific acetylesterase". Plant Cell Rep. 4: 337-340. doi:10.1007/ ...

*Cephalosporin-C deacetylase

... cephalosporin C acetylesterase, cephalosporin C acetyl-esterase, and cephalosporin C deacetylase. This enzyme participates in ... Other names in common use include cephalosporin C acetyl-hydrolase, cephalosporin C acetylase, cephalosporin acetylesterase, ...

*Esterase

Acetylesterase (EC 3.1.1.6), splits off acetyl groups Cholinesterase Acetylcholinesterase, inactivates the neurotransmitter ...

*List of MeSH codes (D08)

... acetylesterase MeSH D08.811.277.352.100.100 --- carboxylesterase MeSH D08.811.277.352.100.150 --- cholesterol esterase MeSH ...

*Serine hydrolase

... acyloxyacyl hydrolase and sialic acid acetylesterase Some amidases, including fatty acid amide hydrolase Some peptidases, ...

*List of EC numbers (EC 3)

... acetylesterase EC 3.1.1.7: acetylcholinesterase EC 3.1.1.8: cholinesterase EC 3.1.1.9: deleted EC 3.1.1.10: tropinesterase EC ... rhamnogalacturonan acetylesterase EC 3.1.1.87: fumonisin B1 esterase EC 3.1.1.88: pyrethroid hydrolase EC 3.1.1.89: protein ... sialate O-acetylesterase EC 3.1.1.54: acetoxybutynylbithiophene deacetylase EC 3.1.1.55: acetylsalicylate deacetylase EC 3.1. ...
Cell wall hemicelluloses and pectins are O-acetylated at specific positions, but the significance of these substitutions is poorly understood. Using a transgenic approach, we investigated how reducing the extent of O-acetylation in xylan affects cell wall chemistry, plant performance and the recalcitrance of lignocellulose to saccharification. The Aspergillus niger acetyl xylan esterase AnAXE1 was expressed in Arabidopsis under the control of either the constitutively expressed 35S CAMV promoter or a woody-tissue-specific GT43B aspen promoter, and the protein was targeted to the apoplast by its native signal peptide, resulting in elevated acetyl esterase activity in soluble and wall-bound protein extracts and reduced xylan acetylation. No significant alterations in cell wall composition were observed in the transgenic lines, but their xylans were more easily digested by a beta-1,4-endoxylanase, and more readily extracted by hot water, acids or alkali. Enzymatic saccharification of lignocellulose ...
Erwinia chrysanthemi causes soft-rot diseases of various plants byenzymatic degradation of the pectin in plant cell walls. Pectin is acomplex polysaccharide. The main chain is constituted of galacturonateresidues, and some of them are modified by methyl and/or acetylesterification. Esterases are necessary to remove these modifications and,thus, to facilitate the further degradation of the polysaccharidic chain.In addition to PaeY, the first pectin acetylesterase identified in the E.chrysanthemi strain 3937, we showed that this bacterium produces a secondpectin acetylesterase encoded by the gene paeX. The paeX open readingframe encodes a 322-residue precursor protein of 34,940 Da, including a21-amino-acid signal peptide. Analysis of paeX transcription, by usinggene fusions, revealed that it is induced by pectic catabolic products andaffected by catabolite repression. The expression of paeX is regulated bythe repressor KdgR, which controls all the steps of pectin catabolism; bythe repressor PecS, ...
The primary structure of AtPAEs revealed that they are unlikely to be membrane proteins and that most isoforms have a basic pI, as suggested in the early literature [17]. However, the predicted GPI anchor for AtPAE10 and AtPAE12, both from clade 2, could indicate a putative role in plant signaling and some interaction with the plasma membrane. The presence of such a predicted GPI anchor has been observed in other pectin-related genes, including PMEI [55]. The absence of a predicted signaling sequence for three AtPAEs, AtPAE2, AtPAE4 and AtPAE5, indicates that some Arabidopsis PAEs without a signal peptide could have a functional activity. Similar results have been observed with several PMEs from distinct plant species and particularly for AtPME31, which has no signaling sequence but is active and cannot be inhibited by the kiwi pectin methylesterase inhibitor, a strong PME inhibitor [56]. 3D homology modeling of AtPME31 revealed an external loop. The function and the mechanism by which AtPME31 ...
123MyMD.com and its services are for informational purposes only and are not a substitute for professional medical or health advice, examination, diagnosis, or treatment. Always seek the advice of your physician or other qualified health professionals before starting any new treatment, making any changes to existing treatment, or altering in any way your current exercise or diet regimen. Do not delay seeking or disregard medical advice based on information on this site. Medical information changes rapidly and while 123MyMD.com and its content providers make every efforts to update the content on the site, some information may be out of date. No health information on 123MyMD.com, including information about herbal therapies and other dietary supplements, is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure, or prevent any disease without the supervision of a medical doctor.. ...
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity.
In molecular biology, haemagglutinin-esterase fusion glycoprotein (HEF) is a multi-functional protein embedded in the viral envelope of several viruses, including influenza C virus, coronaviruses and toroviruses. HEF is required for infectivity, and functions to recognise the host cell surface receptor, to fuse the viral and host cell membranes, and to destroy the receptor upon host cell infection. The haemagglutinin region of HEF is responsible for receptor recognition and membrane fusion, and bears a strong resemblance to the sialic acid-binding haemagglutinin found in influenza A and B viruses, except that it binds 9-O-acetylsialic acid. The esterase region of HEF is responsible for the destruction of the receptor, an action that is carried out by neuraminidase in influenza A and B viruses. The esterase domain is similar in structure to Streptomyces scabies esterase, and to acetylhydrolase, thioesterase I and rhamnogalacturonan acetylesterase. The haemagglutinin-esterase glycoprotein HEF must ...
Colorimetric detection of reaction products is typically preferred for initial surveys of acetyl xylan esterase (AcXE) activity. This chapter will describe common colorimetric methods, and variations...
Abstract: Effect of ethanol on functional activity of isolated perfused rat liver was studied (rate of O2 utilization, absorption of bromosulpholeine from perfusate, bile formation); total activity and activity in supernatant of nine marker enzymes were also determined (malate dehydrogenase, beta-glucuronidase, arylsulphatases A and B, beta-galactosidase, beta-glucosidase, acetylesterase, glucoso-6-phosphatase, alanine aminotransferase and aspartate aminotransferase). Activity of the enzymes was simultaneously studied in perfusate. Ethanol (0.5%) caused distinct impairement in functional activity of isolated liver; rate of bile formation and absorption of bromosulpholeine from perfusate were primarily altered. Degree of impairements in functional activity of liver tissue correlated with the concentration of ethanol in perfusate. In analysis of correlation between the total activity of the enzymes in liver tissue and their activity in supernatants and perfusate it was shown that the concentration ...
Late enzymes of vindoline biosynthesis. S-Adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methylase and unspecific acetylesterase ...
Fusarium oxysporum F3 alone or in mixed culture with Saccharomyces cerevisiae F12 were used to ferment carbohydrates of wet exploded pre-treated wheat straw (PWS) directly to ethanol. Both microorganisms were first grown aerobically to produce cell mass and thereafter fermented PWS to ethanol under anaerobic conditions. During fermentation, soluble and insoluble carbohydrates were hydrolysed by the lignocellulolytic system of F. oxysporum. Mixed substrate fermentation using PWS and corn cobs (CC) in the ratio 1:2 was used to obtain an enzyme mixture with high cellulolytic and hemicellulolytic activities. Under these conditions, activities as high as 34300, 9100, 326, 24, 169, 27 and 254 U dm−3 of xylanase, endoglucanase, β-glucosidase, arabinofuranosidase, avicelase, feruloyl esterase and acetyl esterase, respectively, were obtained. The replacement of the enzyme production phase of F. oxysporum by the addition of commercially available enzymes Celluclast® 1.5 L FG and Novozym® 188 in 3:1 ...
Hydrolases Choi JH, Jeong KJ, Kim SC, Lee SY; Appl Microbiol Biotechnol. 2000 Jun; 53(6): 640-5. Efficient secretory production of alkaline phosphatase by high cell density culture of recombinant Escherichia coli using the Bacillus sp. endoxylanase signal sequence.PubMed. Farias T, Mandrich L, Rossi M, Manco G; Protein Pept Lett. 2007; 14(2):165-9. Biochemical and thermostability features of acetyl esterase Aes from Escherichia coli. PubMed Jefferson RA; US 5432081 A. 1995 Jul. Host cells transformed with the E. coli glucoronide permease gene Jokerst J.C., Adkins J.A., Bisha B., Mentele M.M., Goodridge L. D., Henry C. S.; Chem.; 2012, 84:2900− ...
Chitin deacetylases (CDA) mostly occur in marine bacteria, few in insects, and several in fungi [1].. In fungi, for example, CDAs are involved in cell wall formation, sporulation, and catabolism of chitin oligosaccharides. Many plant fungal pathogens secrete CDAs during plant infection. Plants only detect fungal infections by registering chitin. Fungi "turn invisible" by deacetylating chitin into chitosan and thus, outwit the plant defence system [2].. The CDAs generate chitosan oligomers from chitin by deacetylating the N-acetylglucosamine units of the substrate [3]. During deacetylation, acetic acid is cleaved off from a glucosamine unit. Some CDAs may even deacetylate chitosan, creating a double deacetylated oligomer [2].. Chitin deacetylases belong to the carbohydrate esterase family 4. All family members, including NodB protein and chitin deacetylases, share the same primary structure called "NodB homology domain" or "polysaccharide deacetylase domain" [4].. In medical applications and ...
Plant cell walls consist of three major polymers: cellulose, hemicelluloses and lignin. Cellulose, the most abundant constituent of the plant cell wall, is a homopolysaccharide composed entirely of D-glucose linked together by β-1,4-glucosidic bonds. Xylans, the main hemicelluloses in hardwoods and annual plants, consist of a linear backbone of β-(1→4)-D-xylopyranosyl residues, substituted by α-L-arabinofuranosyl units in the positions of 2-O and/or 3-O, by 4-O-methyl-glucopyranosyl uronic acid in the position of 2-O, and/or by acetyl groups in the positions of 2-O and/or 3-O [1]. Furthermore, some of the arabinofuranosyl units may be esterified with ferulic or p-coumaric acids [2].. Complete hydrolysis of lignocellulosic materials to monosaccharides for fermentation to fuels or chemicals can be accomplished by acid hydrolysis, but enzymatic hydrolysis is preferred due to minimization of the formation of byproducts that inhibit the microbial conversion. Due to the complexity of ...
Enzyme saccharification of pretreated brewers spent grains (BSG) was investigated, aiming at maximising glucose production. Factors investigated were; variation of the solids loadings at different cellulolytic enzyme doses, reaction time, higher energy mixing methods, supplementation of the cellulolytic enzymes with additional enzymes (and cofactors) and use of fed-batch methods. Improved slurry agitation through aerated high-torque mixing offered small but significant enhancements in glucose yields (to 53 ± 2.9 g/L and 45% of theoretical yield) compared to only 41 ± 4.0 g/L and 39% of theoretical yield for standard shaking methods (at 15% w/v solids loading). Supplementation of the cellulolytic enzymes with additional enzymes (acetyl xylan esterases, ferulic acid esterases and α-L- arabinofuranosidases) also boosted achieved glucose yields to 58 - 69 ± 0.8 - 6.2 g/L which equated to 52 - 58% of theoretical yield. Fed-batch methods also enhanced glucose yields (to 58 ± 2.2 g/L and 35% of ...
acetyl xylan esterase (EC 3.1.1.72); chitin deacetylase (EC 3.5.1.41); chitooligosaccharide deacetylase (EC 3.5.1.-); peptidoglycan GlcNAc deacetylase (EC 3.5.1.-); peptidoglycan N-acetylmuramic acid deacetylase (EC 3.5.1.- ...
LSE CareerHub should be your main job hunting resource as an LSE student or recent graduate, but there are many other employment websites you can use in addition to maximise your chances of finding work. It is important to choose an appropriate website before starting your online job search. Typing a job title, employer and location into a general search engine like Google or Bing may lead to an occasional lucky discovery, but for a more efficient search you will require a job listings website. These websites come in two main varieties, job boards and aggregate job sites. ...
I am a GCSE student who is predicted 8 A* and 4 A grades for GCSE. Unfortunately, I do not think I got l got the A* I wanted in Maths. I am dreaming of doing Economics at LSE. Do I need an A* at GCSE in Maths to do Economics at LSE, despite getting maybe 8 or so A* in other subjects? Of course, A Levels still have a bigger role to play but I really want to hit the ground running ...
3VUS: The structure of the deacetylase domain of Escherichia coli PgaB, an enzyme required for biofilm formation: a circularly permuted member of the carbohydrate esterase 4 family
I just received my offer pack from LSE and it said nothing about a deposit I might need to pay in order to accept the offer. Still, I am not very sure what would happen if I were to accept it now and not actually register (As my situation is pretty much the same as MPAs - Im waiting for schorlarship answers). On the other hand, it does say that they are expecting an answer within 6 weeks BUT your offer will not be withdrawn if they dont get it in this time frame and you should reply as soon as possible ...
6-sulfo sialyl Lewis X is the common receptor determinant recognized by H5, H6, H7 and H9 influenza viruses of terrestrial poultry. (2008 ...
Complete information for SPIB gene (Protein Coding), Spi-B Transcription Factor, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
Bronnenberg, Bart J. and Rossi, Peter E. and Vilcassim, Naufel J. (2005) Structural modeling and policy simulation. Journal of Marketing Research, 42 (1). pp. 22-26. ISSN 0022-2437 ...
Access our extensive online library to review LSE Consultings latest publications and reports, categorised by easily identifiable themes.
In the present study, twenty-three strains of Piromyces sp. obtained from ruminants and non-ruminants were grown in Medium 10 in the presence of paddy straw as the sole source of fermentable carbon. The activity of extra-cellular fibrolytic enzymes such as avicelase, filter paper cellulase, β 1, 4 endoglucanase, β glucosidase and acetyl esterase were estimated in the various axenic cultures. The activity of the exoglucanase on avicel (avicelase activity) and filter paper was found to be significantly higher (P<0.05) in the Piromyces strains isolated from Nilghai, the Indian elephant and the camel. In the four strains of the Piromyces isolated from the domestic ruminants, the activity of the exoglucanase on avicel (avicelase activity) and filter paper was found to be the lowest as compared to all other strains of Piromyces isolated from the wild herbivores, camel/horse (< 4.0 µmoles/mg protein).
A glucuronoyl esterase (GE) from the thermophilic fungus Sporotrichum thermophile, belonging to the carbohydrate esterase family 15 (CE-15), was functionally expressed in the methylotrophic yeast Pich
1111269DNAHumicola insolens 1atgaaggtcc cgactctcat ctcgagcctc ctggctctgg tctccttctc cgaggccacg 60ccgctcatca agcgagcgac gctcacgcgg gtcaacaact tcggtaacaa ccctagcggt 120gcgcgcatgt acatctatgt gcccgacagg cttcagccac gtcctgccgt tctcacggcc 180gttcactact gcacgggcac cgccaacgcc ttctacaccg gtactccgta tgctcgtctt 240gccgaccagt atggcttcat tgtcgtctac ccggagtctc ccaataacgg cggttgctgg 300gatgtctcgt cccgcgctgc ctacacccgc gatagcggtt ccaacagcca cgccatttct 360ctcatgacga agtgggctct gcagcaatat aatggtgacc cagagaaggt ctttgttgcc 420ggcaccagct cgggcgctat gatgacggtg agtgacacag agatgaggct caagttgtgg 480tcagctacct tgtcccggtt actgacacct gtctcaccag aatgttctct ctgctgtgta 540ccctgatctg tacaaggctg ccgctgccta cgctggtgtc cctgcgggct gcttctacac 600gggcactgtt gctggctgga actcgacttg cgccaacggc cagtccatta ccactcagga 660acactgggcc aggacggcgc tcgatatgta ccctggctac accggcccgc gtccacgcat 720gctcatctac cacggctccg ctgacacgac catctatcct cgggtaagcc ctatgccccc 780caaaaagcag gctattggac ctccaataac tgacaaccgc cgcagaactt caacgagact 840ctgaagcagt ...
The acetyl xylan esterase II gene from Penicillium purpurogenum is differentially expressed in several carbon sources, and tightly regulated by pH ...
The family 15 carbohydrate esterase (CE15) MZ0003, which derives from a marine Arctic metagenome, has a broader substrate scope than other members of this family. Here we report the crystal structure of MZ0003, which reveals that residues comprising the catalytic triad differ from previously-characterized fungal homologs, and resolves three large loop regions that are unique to this bacterial sub-clade. The catalytic triad of the bacterial CE15, which includes Asp 332 as its third member, closely resembles that of family 1 carbohydrate esterases (CE1), despite the overall lower structural similarity with members of this family ...
All cells are decorated on their surfaces with a complex array of oligosaccharides (glycans) that are attached to membrane glycoproteins and glycolipids or which make up the different components of soluble extracellular materials such as mucus and which are involved in the initial interactions of viruses or other pathogens with cells or mucosal surfaces (1). The chemical diversity of these glycans contributes to their complex functional roles in controlling cell-cell, cell-pathogen, and cell-environment interactions. Linear and branched glycoconjugates of vertebrate cells are often terminated in sialic acids (Sias). Sias have critical roles in maintaining a variety of cell functions due to their abundance as exposed terminal sugars, where they are involved in highly specific and regulated cellular lectin interactions (2, 3). They have also been exploited by many different pathogens as well as by nonpathogenic microbes for host recognition and attachment, including playing a role as receptors for ...
1JT2: Structural basis for the substrate specificity of the feruloyl esterase domain of the cellulosomal xylanase Z from Clostridium thermocellum.
Mouse monoclonal antibody raised against a full-length recombinant SIAE. SIAE (NP_733746.1, 1 a.a. ~ 523 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. (H00054414-M) - Products - Abnova
The best way to accommodate the young, the Scots and the Irish is to continue to allow free movement. But the only way to contain immigration is to introduce some new controls.. Assessing the balance between free movement and control of immigration should take account not only of the costs of access to the single market, such as the net UK fiscal contribution and the acknowledged problems of the EU, but also its benefits. Membership of the worlds largest market brings direct economic benefits, greater influence over trade rules and greater leverage in negotiations with third parties. The single market is so large that no other trading power can ignore its clout in negotiations. And as discussed, Brits also benefit from immigration, and many benefit from living in other EU countries.. A partial solution is a proposal by my LSE colleague Richard Bronk to exclude students and young graduates from net-migration numbers and exempt students and recent graduates of bona fide university courses below, ...
Friedman, SD; Hebrard, G; Tripp, TM; Chayer, P; and Sembach, KR, "The deuterium, oxygen, and nitrogen abundance toward LSE 44" (2006). ASTROPHYSICAL JOURNAL. 721 ...
In the largest international listing by any Indian firm, the Ruias-managed Essar Energy Ltd on Thursday announced plans to raise $2.5 billion (Rs 11,250 crore) through an initial public offering on the London Stock Exchange (LSE) to institutional investors.
Detailed Share Price, Charts and News for Diurnal Group Plc [LSE,DNL]. Share Market Tools for Successful Investing. Global Share Market database including US, Canada, London, Singapore, Australia, Hong Kong, and New Zealand.
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More... ...
the evolutionist: Another transition people might be interested in is the origin of sex. What was the first sexual act? JMS: Theres a broad and a narrow definition of sex. The broad definition would be any process that results in an organism receiving genetic material, genes if you like, from two different ancestors. That probably goes way back into the past; it is present in bacteria. I nowadays spend my life looking at the evidence of bacteria exchanging genes. Thats a kind of sexual process. But most people, when they think of sex, think of it as how we do it. In ourselves -- and all higher organisms -- the new individual starts with the fusion of two gametes, two cells, which contribute more or less equal amounts of information to the individual. And basically when one talks about the evolution of sex its that fusion of two totally different cells that we think of. If you have cells swimming around with just a single set of chromosomes, fusing has real advantages because you cover up the ...
Scholars estimating policy positions from political texts typically code words or sentences and then build left-right policy scales based on the relative frequencies of text units coded into different categories. Here we reexamine such scales and propose a theoretically and linguistically superior alternative based on the logarithm of odds-ratios. We contrast this scale with the current approach of the Comparative Manifesto Project (CMP), showing that our proposed logit scale avoids widely acknowledged flaws in previous approaches. We validate the new scale using independent expert surveys. Using existing CMP data, we show how to estimate more distinct policy dimensions, for more years, than has been possible before, and make this dataset publicly available. Finally, we draw some conclusions about the future design of coding schemes for political texts.. ...
In the theory of judgment aggregation, it is known for which agendas of propositions it is possible to aggregate individual judgments into collective ones in accordance with the Arrow-inspired requirements of universal domain, collective rationality, unanimity preservation, nondictatorship and propositionwise independence. But it is only partially known for which agendas it is possible to respect additional requirements, notably non-oligarchy, anonymity, no individual veto power, or implication preservation. We fully characterize the agendas for which there are such possibilities, thereby answering the most salient open questions about propositionwise judgment aggregation. Our results build on earlier results by Nehring and Puppe (2002), Nehring (2006) and Dietrich and List (2007a).. ...
The UPD (Urbanisation, Planning and Development) research cluster (formerly Cities Research Cluster) brings together a key group of staff in the
Binds to the N-acetyl-9-O-acetylneuraminic acid residues on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HEF2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. Displays a receptor-destroying activity which is a neuraminidate-O-acetyl esterase. This activity cleaves off any receptor on the cell surface, which would otherwise prevent virions release. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell (By similarity).
acetyl xylan esterase (EC 3.1.1.72); cinnamoyl esterase (EC 3.1.1.-); feruloyl esterase (EC 3.1.1.73); carboxylesterase (EC 3.1.1.1); S-formylglutathione hydrolase (EC 3.1.2.12); diacylglycerol O-acyltransferase (EC 2.3.1.20); trehalose 6-O-mycolyltransferase (EC 2.3.1.122 ...
1( the rid book a primer in social choice theory revised edition lse perspectives in controls) and the center school. book a primer in social choice theory revised edition lse perspectives school and buy these clerks to hold content. generate the book a primer in social of each software with a control corner. go these blocks in Column K. Record these cells in Column L. Record this book a primer in social choice theory revised edition lse perspectives in on labour 5. thank this book on content 6. like this book a in Column N. continuing integrin - Woody Shrub? coordinate in the book a primer in social choice theory run at the pocket of Sheet L2. Photo Plot Data for Sheet L2. 5) if the book a primer in social choice theory revised edition lse perspectives in can Let signed. have this weeks in Columns C and E. Describe the old book of each web century. Appendix 6 for the Supervised data. Classified book a primer in social choice theory activity role the ARC leukocyte to the reference. win this book ...
Author Summary Glycans cover the surface of every living cell. In vertebrates, these sugar trees commonly terminate with sialic acid (Sia) and, in consequence, Sias have become the attachment factors of choice for a multitude of pathogens: protozoa, bacteria and viruses alike. To ensure selectivity, viruses evolved to target distinct Sia species. Whether a particular type of Sia serves as receptor may depend -amongst others- on the absence or presence of specific Sia modifications. For example, most group A betacoronaviruses attach to 9-O-acetylated Sias. However, some murine coronaviruses have switched to using 4-O-acetylated Sias instead. In chemical/molecular terms this represents a momentous shift in receptor usage. We now have crystallized the hemagglutinin-esterase protein (HE) of a murine coronavirus and have solved the structure of its sugar-binding domain. Our findings reveal in exquisite detail the interactions between Sia binding site and cognate receptor. The data allow a reconstruction of
Using sialic acid analogues to define the molecular basis of complement resistance mediated by sialylation of neisseria gonorrhoeae lipopolysaccharide and to design novel therapeutics
If that were all there was today it would not be bad. However, we will also do more on the riveting battle for ITV. BSkyBs Friday purchase of 17.9 per cent of ITV will be discussed at Ofcom today but whether it goes further depends on their definition of "material influence" and whether BSkyB now has it at ITV. It is worth noting that Nasdaq has been allowed to hold 25 per cent of the LSE. But the media tends to get treated differently. Will Whitehorn of Virgin was on Radio Five Live last night with Jeff Randall and me, making an impassioned but not entirely convincing case. Channel 4 chairman Luke Johnson was on as well. He saw Skys move as a simple attempt to thwart NTL but took the opportunity also to say how amazing it is that ITVs board will probably have taken at least six months to find a chief executive, when it took him six weeks at Channel 4. BSkyB shares are down only 1.3 per cent this morning and ITV shares, having fallen sharply at first this morning, are now down just 1.4 per ...
The LSE Companion to Health Policy covers a wide range of conceptual and practical issues from a number of different perspectives introducing the reader to, and summarising, the vast literature that analyses the complexities of health policy. The Companion also assesses the current state of the art ...
1998 - 2017 The Motley Fool. All rights reserved. The Motley Fool, Fool, and the Fool logo are registered trademarks of The Motley Fool Holdings Inc.. The Motley Fool Ltd. Registered Office: 60 Charlotte Street, London W1T 2NU.. Registered in England & Wales. Company No: 3736872. VAT Number: 188035783. ...
Membrane-permeable fluorescent probe that labels human, mouse or rat neurons derived from primary tissues or pluripotent stem cells.
4-Nitrophenyl N-acetyl-α-D-galactosaminide is a chromogenic substrate for N-acetyl-D-galactosaminidase, generating a yellow solution upon N-acetyl-D-galactosaminidase ca
30750-55-1 - DJUKMSKWRAHKNJ-KQOKFJBASA-N - Oxytocin, N-acetyl-2-O-methyl-tyr- - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.. ...
This concludes being on the shop, but is you to use the repository of your image world yourself, by working in dogs real as methodology, everyday, martial support and complicated phenomenon. LSE is altogether mobility-enabled for its heaven and review, and effectively, is a medieval GB of clubbing download with a request of vv and case. authors may be sought by perceptual games of chromosome, only as industrial Remarks, explanation products and images.
NOTTINGHAM, UNITED KINGDOM--(Marketwired - Aug 12, 2014) - Scancell Holdings plc (LSE: SCLP) (AIM: SCLP) (Scancell or the Company), the developer of novel immunotherapies for the treatment of cancer, is pleased to announce new data demonstrating that animals treated with a combination of SCIB1, Scancells ImmunoBody® vaccine in development for...
Werries, E., Wollek, E., Gottschalk, A. and Buddecke, E. (1969). „Separation of N-acetyl-α-glucosaminidase and N-acetyl-α-galactosaminidase from ox spleen. Cleavage of the O-glycosidic linkage between carbohydrate and polypeptide in ovine and bovine submaxillary glycoprotein by N-acetyl-α-galactosaminidase". Eur. J. Biochem. 10: 445-449. PMID 5348072 ...
引用Abcams Anti-p53 (acetyl K381)抗体(ab61241)的参考文献列表。为您列举引用本产品的发表文章,并提供信息包括论文文献数据库中的检索编号以便您搜寻文章
A New Concept of European Federalism LSE Europe in Question Discussion Paper Series Europe, for example Simon Glendinning LEQS Paper No. 31/2011 March 2011 Editorial Board Dr. Joan Costa-i-Font Dr. Mareike
Deacetylation of de novo synthesized 9-O-acetyl GD3 triggers apoptosis of HEK-293 cells. (A) GD3 and 9-O-acetyl GD3 content of HEK-293 cells was analyzed by TLC
American professor Craig Calhoun, 65, voiced admiration for the Labour leaders rail nationalisation plans and publicly backed Remain while leading the London School of Economics.
3 Ideal: Study human behavior in real life settings But unfortunately... Nature rarely creates the circumstances that allow a clear view and a precise measurement of the psychological elements at work.
The number of deaths from chronic diseases is higher in sub-Saharan Africa than in virtually all other regions of the world, yet far too little attention is paid to the problem, according to a report launched at the London School of Economics (LSE).. The report synthesises key insights from an international conference organised by the British Academy, the Royal Society, and the Ghana Academy of Arts and Sciences in February 2009 at the British Council in Accra.. Written by LSE health visiting fellow Ama de-Graft Aikins, it provides an overview of multidisciplinary and multi-institutional perspectives, and highlights both challenges and good practices in research, practice, … ...
After a tough six months, is there now fresh hope for Hornby (LSE: HRN) shareholders? No worse than expected The model toy and train company announced its annual results this morning, alongside
Health, ... LONDON Fe... - Faster Than its Competition and to Strengthen Expansion Plans/p... Misys plc (LSE: MSY) the global application software and services... Misys Equation has added value to Piraeus Banks operations for ma...,Piraeus,Licenses,Misys,BankFusion,Equation,to,Deliver,Products,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
xml version="1.0" encoding="UTF-8"?, ,Deployments, ,Node Name="development", ,Deployment Id="StandardMetadata.jddgmm4tjddgmm4u" Class="com.interwoven.livesite.lscs.model.LSCSDeploymentImpl" Instance="jddgmm4tjddgmm4u", ,Name,StandardMetadata,/Name, ,TargetEnviroment,development,/TargetEnviroment, ,LastExecutionTime Class="java.util.Date" Month="2" DayOfMonth="10" DayOfWeek="6" Year="2018" Hour="5" Minute="49" Second="4" ZoneOffsetMillis="0" Time="1518241744540",Sat Feb 10 05:49:04 UTC 2018,/LastExecutionTime, ,/Deployment, ,Vpath,/default/main/bio-rad/WORKAREA/default/templatedata/internet/generic/data/LSE/page_EDUPriceOverlay_1375183846_XX.xml,/Vpath, ,LastExecutionTime Class="java.util.Date" Month="2" DayOfMonth="10" DayOfWeek="6" Year="2018" Hour="5" Minute="49" Second="4" ZoneOffsetMillis="0" Time="1518241744540",Sat Feb 10 05:49:04 UTC 2018,/LastExecutionTime, ,/Node, ,Node Name="PROD", ,Deployment Id="StandardMetadata.jddgmm4zjddgmm50" ...
This might be a hard one to pull off, but if you have any vids of Delta kids post them here. I was inspired by watching this funny vid of a kid who Im pretty sure is LSE :): http://www.youtube.com/watch?v=2T_obaO46Bo
Washington, DC and London, UK: 4 April 2006 Cancer drug developer Antisoma plc (LSE: ASM, US OTC: ATSMY) announces that new data on its aptamer drug AS1411 will be presented today at the American Asso...
The merger of the New York Stock Exchange (NYSE) and Euronext could lead to a new market in London to compete with the London Stock Exchange (LSE), it was reported today
BREO ELLIPTA now available in the U.S. for the treatment of COPD GlaxoSmithKline plc (LSE NYSE GSK) and Theravance, Inc. (NASDAQ THRX) today announced that BREO
A new esterase from Thermobifida halotolerans (Thh_Est) was cloned and expressed in E. coli and investigated for surface hydrolysis of polylactic acid (PLA) and polyethylene terephthalate (PET). Thh_Est is a member of the serine hydrolases superfamily containing the -GxSxG- motif with 85-87% homology to an esterase from T. alba, to an acetylxylan esterase from T. fusca and to various Thermobifida cutinases. Thh_Est hydrolyzed the PET model substrate bis(benzoyloxyethyl)terephthalate and PET releasing terephthalic acid and mono-(2-hydroxyethyl) terephthalate in comparable amounts (19.8 and 21.5 mmol/mol of enzyme) while no higher oligomers like bis-(2-hydroxyethyl) terephthalate were detected. Similarly, PLA was hydrolyzed as indicated by the release of lactic acid. Enzymatic surface hydrolysis of PET and PLA led to a strong hydrophilicity increase, as quantified with a WCA decrease from 90.8° and 75.5° to 50.4° and to a complete spread of the water drop on the surface, respectively.
A new esterase from Thermobifida halotolerans (Thh_Est) was cloned and expressed in E. coli and investigated for surface hydrolysis of polylactic acid (PLA) and polyethylene terephthalate (PET). Thh_Est is a member of the serine hydrolases superfamily containing the -GxSxG- motif with 85-87% homology to an esterase from T. alba, to an acetylxylan esterase from T. fusca and to various Thermobifida cutinases. Thh_Est hydrolyzed the PET model substrate bis(benzoyloxyethyl)terephthalate and PET releasing terephthalic acid and mono-(2-hydroxyethyl) terephthalate in comparable amounts (19.8 and 21.5 mmol/mol of enzyme) while no higher oligomers like bis-(2-hydroxyethyl) terephthalate were detected. Similarly, PLA was hydrolyzed as indicated by the release of lactic acid. Enzymatic surface hydrolysis of PET and PLA led to a strong hydrophilicity increase, as quantified with a WCA decrease from 90.8° and 75.5° to 50.4° and to a complete spread of the water drop on the surface, respectively.
Macrophomina phaseolina is one of the most destructive necrotrophic fungal pathogens that infect more than 500 plant species throughout the world. It can grow rapidly in infected plants and subsequently produces a large amount of sclerotia that plugs the vessels, resulting in wilting of the plant. We sequenced and assembled ~49 Mb into 15 super-scaffolds covering 92.83% of the M. phaseolina genome. We predict 14,249 open reading frames (ORFs) of which 9,934 are validated by the transcriptome. This phytopathogen has an abundance of secreted oxidases, peroxidases, and hydrolytic enzymes for degrading cell wall polysaccharides and lignocelluloses to penetrate into the host tissue. To overcome the host plant defense response, M. phaseolina encodes a significant number of P450s, MFS type membrane transporters, glycosidases, transposases, and secondary metabolites in comparison to all sequenced ascomycete species. A strikingly distinct set of carbohydrate esterases (CE) are present in M. phaseolina, with the
Shop O-acetyl-ADP-ribose deacetylase ELISA Kit, Recombinant Protein and O-acetyl-ADP-ribose deacetylase Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
You wont find this reported in any of the Malaysian newspapers. I was alerted about this by a fellow blogger and special assistant to Anwar, Nik Nazmi. You can read the full details here. I somehow fail to understand what the MSD in the UK hopes to achieve by pressuring these student organizations. Will it make it less likely that any students who already intended to attend Anwars talk would suddenlydecide not to go at the MSDs insistence? I think better of LSE and Cambridge students (hopefully, Im not proven wrong). Will it make it more likely that the talks by Anwar will be cancelled? Not likely if hes been invited by the university and not the Malaysian student organizations situated in these universities ...
Looking for the meaning of o-acetyl-adp-ribose? Find out what is the meaning of o-acetyl-adp-ribose on Phrases.net! The Webs largest and most authoritative phrases and idioms resource.
So if you value an opinion, formed as a result of participating in many ME activities, for example being bed bound for years, you have come to the right BLOG. All these activities have allowed me to form an opinion as a Doctor and as a Patient. And that is important as the voice of the latter is discarded by many including NICE ...
The London Stock Exchange is to launch a new feed of Italian market data from subsidiary Borsa Italiana that will utilize the FAST (FIX Adapted for Streaming) Protocol for data compression, as part of version 5.0 of its TradElect trading engine, which wi
Definition of N-acetyl-6-hydroxytryptophan oxidase with photos and pictures, translations, sample usage, and additional links for more information.
Bacillus pumilus ATCC ® 27142™ Designation: E601 TypeStrain=False Application: Ionizing radiation-sterilization control Sterility assurance Pharmaceutical and Personal Care
Finance Division provides the monetary framework the College neighborhood operates within. And finance has turn into, in my view, the tail that wags the canine for trade, relatively than the other approach round. In the 1960s the larger cities on this country didnt seem like they do as we speak, my hometown of Scranton Pa was a slimy soiled depressing mess. With a deep understanding of your industry, processes and enterprise issues, Experis Finance brings solutions and talent collectively to take in your danger advisory , finance & accounting and tax challenges. As far as CFA-ICFAI is concenrned go for it, as I did, incomes in million INR now… Give time, you cant earn million overnight… Be taught and be a master of the subject.. and above all YOUR INBORN INTELLIGENCE. Detailed tips for taking and submitting a quality photograph are on the U.S. Department of State web site here.. The LSE Department of Finance (formerly part of the Department of Accounting and Finance) has grown in recent ...
Health,...CHICAGO October 29 2008 Shire plc (LSE: SHP NASDAQ: SHPGY) the gl... The study presented today is the first published data demonstrating i...This study confirms the results of a previous clinical trial in which ... This is encouraging news for physicians and patients seeking a long-a...,VYVANSE,provided,behavior,,inattention,and,math,test,score,improvements,in,children,with,ADHD,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
KINGSTON ValueRam/ 4GB 1333MHz DDR3L ECC CL9 SODIM (KVR13LSE9S8/4) - ECC: Ja - Formfaktor: SO-DIMM - Hastighet: 1333 MHz - Minnestørrelse: 4GB - Registered: Nei - Type: DDR3
The Board of Dechra Pharmaceuticals PLC ( LSE: Stock Code: Full Listing (Pharmaceuticals) issues the following unaudited pre-close trading update for the Groups financial year
Shares in Neil Woodford favourite ReNeuron Group(LSE: RENE) jumped in early deals this morning after the company announced a positive result from its Phase II clinical trial of its CTX cell therapy candidate for stroke disability. It looks as if the
LG Få produktsupport för LG S1-J2BCV. Hämta S1-J2BCV manualer, dokument och programvara. Visa S1-J2BCV garantiinformation och schemaläggningstjänster.
A previous study (Bergwerff et al., Biochimie 74 (1992) 25-37) reported that sialic acids present in Asterias rubens gonads were essentially composed of 8-methyl-N-glycolylneuraminic acid (Neu5Gc8Me), a large part of it being acetylated in position 9
Tannerella forsythia, a Gram-negative member of the Bacteroidetes has evolved to harvest and utilize sialic acid.. The most common sialic acid in humans is a mono-N-acetylated version termed Neu5Ac. Many bacteria are known to access sialic acid using sialidase enzymes. However, in humans a high proportion of sialic acid contains a second acetyl group attached via an O- group i.e. chiefly O-acetylated Neu5,9Ac2 or Neu5,4Ac2. This diacetylated sialic acid is not cleaved efficiently by many sialidases and in order to access diacetylated sialic acid, some organisms produce sialate-O-acetylesterases that catalyse removal of the second acetyl group. In this study we performed bioinformatic and biochemical characterization of a putative sialate-O-acetylesterase from T. forsythia (NanS), which contains two putative SGNH-hydrolase domains related to sialate-O-acetylesterases from a range of organisms. Purification of recombinant NanS revealed an esterase that has activity against Neu5,9Ac2 and its ...
Lecture Notes and other materials for the course are available from the Medical Mycology Site http://microbiology.okstate.edu/faculty/prade. Lectures: Thursday 12:30-01:20PM - LSE 215. Section 1: Lab Monday/Wednesday 10:00-11:50AM - LSE101. Section 2: Lab Tuesday/Thursday 10:00-11:50AM - LSE101. Instructor R A Prade LSE409 Tel 4 7522. Teaching Assistant Nick Kuburich, LSE401 Tel 4 7284. Office hours by appointment E-mail [email protected] or [email protected] Objectives and Format This course has been designed to give students a unique opportunity to observe and explore the world of fungi and to be exposed to the many problems and modern issues related to the discomfort that fungi cause to humans. As you probably are aware, myco-infections are becoming alarmingly common in recent years and a great deal of attention is being given to fungal infections. Two modules contain the course: lectures (that will provide you with historical and contemporary background information) and ...
Trevor Sewell from Structural Biology, at the IDM, UCT, will present the Department of Molecular & Cell Biology seminar with a talk entitled, The structure of the cyanide dihydratase from Bacillus pumilus. What does it tell us?.. ...
Creative-Proteomics offer cas 6974-32-9 1-O-acetyl 2, 3, 5-tri-O-benzoyl-β-D-[UL-13C5] ribofuranoside. We are specialized in manufacturing Stabel Isotope Labeled Analytical Standard products.
MANCHESTER, UNITED KINGDOM--(Marketwired - Feb. 12, 2015) - Epistem Holdings Plc (LSE:EHP), the Personalised Medicine and Biotechnology company, announces today the successful evaluation of RNA-Amp™ for single cell expression profiling. The results have been published in BMC Genomics (Rothwell et al. (2014). 15:1129) and compare amplified cDNA derived from three...
xml version="1.0" encoding="UTF-8"?, ,Deployments, ,Node Name="development", ,Deployment Id="StandardMetadata.jddgmm4tjddgmm4u" Class="com.interwoven.livesite.lscs.model.LSCSDeploymentImpl" Instance="jddgmm4tjddgmm4u", ,Name,StandardMetadata,/Name, ,TargetEnviroment,development,/TargetEnviroment, ,LastExecutionTime Class="java.util.Date" Month="2" DayOfMonth="10" DayOfWeek="6" Year="2018" Hour="5" Minute="49" Second="4" ZoneOffsetMillis="0" Time="1518241744540",Sat Feb 10 05:49:04 UTC 2018,/LastExecutionTime, ,/Deployment, ,Vpath,/default/main/bio-rad/WORKAREA/default/templatedata/internet/generic/data/LSE/page_EDUPriceOverlay_1375183846_XX.xml,/Vpath, ,LastExecutionTime Class="java.util.Date" Month="2" DayOfMonth="10" DayOfWeek="6" Year="2018" Hour="5" Minute="49" Second="4" ZoneOffsetMillis="0" Time="1518241744540",Sat Feb 10 05:49:04 UTC 2018,/LastExecutionTime, ,/Node, ,Node Name="PROD", ,Deployment Id="StandardMetadata.jddgmm4zjddgmm50" ...
888 HOLDINGS PLC ORD 0.5P (LSE_EOD:888). Get more trading ideas from themarketzone. Follow market experts, get opinions and be heard! Join the largest trading & investing community on the planet.
Shares of Xylan plunged a day after the maker of computer-networking equipment reported fourth-quarter results failed to meet analysts expectations.
Title: A Sialic Acid-Specific Lectin from the Mushroom Paecilomyces Japonica that Exhibits Hemagglutination Activity and Cytotoxicity. VOLUME: 11 ISSUE: 6. Author(s):Jee Hun Park, Chang Soo Ryu, Ha Na Kim, Young Jun Na, Hyun Joo Park and HaHyung Kim. Affiliation:Physical Pharmacy Laboratory, College of Pharmacy, Chung-Ang University, 221 Huksuk-dong, Dongjakku, Seoul 156-756, Korea Correspondence To: HaHyung Kim.. Keywords:sialic acid, lectin, mushroom, paecilomyces japonica, hemagglutination, cytotoxicity. Abstract: The mushroom Paecilomyces japonica, grown on the silkworm larvae, has been used in Asia as a nutraceutical, tea, and Chinese medicine. In the present study, a sialic acid-specific lectin has been purified from the mushroom P. japonica using affinity chromatography on a fetuin-agarose column. Electrophoretical analyses indicated that this lectin, designated P. japon ica agglu tinin (PJA), is an acidic protein with a molecular mass of 16 kDa, and has no intermolecular disulfide bonds. ...
Looking for Esterases? Find out information about Esterases. Any of a group of enzymes that catalyze the synthesis and hydrolysis of esters. any of the enzymes of the hydrolase class that catalyze the cleavage of the... Explanation of Esterases
Looking for online definition of alpha/beta hydrolase domain-containing protein 3 in the Medical Dictionary? alpha/beta hydrolase domain-containing protein 3 explanation free. What is alpha/beta hydrolase domain-containing protein 3? Meaning of alpha/beta hydrolase domain-containing protein 3 medical term. What does alpha/beta hydrolase domain-containing protein 3 mean?
0043]In one exemplary embodiment, a transformed bacterial host cell with a mutant ferulic acid esterase gene is constructed. A mutant ferulic acid esterase gene is inserted into a pG+host5 vector. The mutant ferulic acid esterase gene is then transferred into bacterial host cells using electroporation. The mutant ferulic acid esterase then becomes part of the bacterial host cells genome by recombination. The bacterial host cells can be Lactobacillus buchneri cells. In some embodiments, the Lactobacillus buchneri cells will be Lactobacillus buchneri strain PTA-6138 cells. The mutant ferulic acid esterase gene can be a knock out. New strains of Lactobacillus buchneri with mutant, including knocked-out ferulic acid esterase, can be used as negative controls. For example, a transformed Lactobacillus buchneri strain can be used in an assay for studying the impact of ferulic acid esterase activity. One example of such an assay would be inoculating whole plant material, such as whole plant silage, with ...

Plant pectin acetylesterase structure and function: new insights from bioinformatic analysis | BMC Genomics | Full TextPlant pectin acetylesterase structure and function: new insights from bioinformatic analysis | BMC Genomics | Full Text

Pectin acetylesterase Arabidopsis thaliana Phylogenetic treeConserved motifs3D homology. Background. The plant primary cell ... Gou J-Y, Miller LM, Hou G, Yu X-H, Chen X-Y, Liu C-J. Acetylesterase-Mediated Deacetylation of Pectin Impairs Cell Elongation, ... A novel protein from mung bean hypocotyl cell walls with acetyl esterase activity. Phytochemistry. 1995;38:315-9.View Article ... The degree of acetylation of pectin can be modulated by pectin acetylesterase (EC 3.1.1.6, PAE). The function and structure of ...
more infohttps://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-017-3833-0

SMART: Secondary literature for HTH ICLR domainSMART: Secondary literature for HTH ICLR domain

... the first pectin acetylesterase identified in the E.chrysanthemi strain 3937, we showed that this bacterium produces a ... secondpectin acetylesterase encoded by the gene paeX. The paeX open readingframe encodes a 322-residue precursor protein of ...
more infohttp://smart.embl-heidelberg.de/smart/show_secondary.cgi?domain=HTH_ICLR

Expression of fungal acetyl xylan esterase in Arabidopsis thaliana improves saccharification of stem lignocelluloseExpression of fungal acetyl xylan esterase in Arabidopsis thaliana improves saccharification of stem lignocellulose

... resulting in elevated acetyl esterase activity in soluble and wall-bound protein extracts and reduced xylan acetylation. No ...
more infohttp://umu.diva-portal.org/smash/record.jsf?pid=diva2:912450

Sialate O-acetylesterase domain (IPR005181) | InterPro | EMBL-EBISialate O-acetylesterase domain (IPR005181) | InterPro | EMBL-EBI

Sialate O-acetylesterase domain (IPR005181). Short name: SASA Overlapping homologous superfamilies *SGNH hydrolase superfamily ... Functionally defective germline variants of sialic acid acetylesterase in autoimmunity.. Nature 466 243-7 2010 ...
more infohttp://www.ebi.ac.uk/interpro/entry/IPR005181

aes - Acetyl esterase - Shigella flexneri - aes gene & proteinaes - Acetyl esterase - Shigella flexneri - aes gene & protein

Acetyl esteraseAdd BLAST. 319. Proteomic databases. PaxDb, a database of protein abundance averages across all three domains of ... Acetyl esteraseUniRule annotation. ,p>Manual validated information which has been generated by the UniProtKB automatic ... IPR023508. Acetyl_esterase. IPR002168. Lipase_GDXG_HIS_AS. IPR033140. Lipase_GDXG_put_SER_AS. ... IPR023508. Acetyl_esterase. IPR002168. Lipase_GDXG_HIS_AS. IPR033140. Lipase_GDXG_put_SER_AS. ...
more infohttp://www.uniprot.org/uniprot/Q83M39

Acetylesterase - WikipediaAcetylesterase - Wikipedia

In enzymology, an acetylesterase (EC 3.1.1.6) is an enzyme that catalyzes the chemical reaction an acetic ester + H2O ⇌ {\ ... Jansen EF; Nutting M-DF; Balls AK (1948). "The reversible inhibition of acetylesterase by diisopropyl fluorophosphate and ... and Citrus acetylesterase. As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes ...
more infohttps://en.wikipedia.org/wiki/Acetylesterase

Rhamnogalacturonan acetylesterase - WikipediaRhamnogalacturonan acetylesterase - Wikipedia

Rhamnogalacturonan acetylesterase (EC 3.1.1.86, RGAE) is an enzyme with systematic name rhamnogalacturonan 2/3-O-acetyl-alpha-D ... Rhamnogalacturonan acetylesterase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ... Molgaard, A.; Kauppinen, S.; Larsen, S. (2000). "Rhamnogalacturonan acetylesterase elucidates the structure and function of a ... "Molecular cloning and characterization of a rhamnogalacturonan acetylesterase from Aspergillus aculeatus. Synergism between ...
more infohttps://en.wikipedia.org/wiki/Rhamnogalacturonan_acetylesterase

RCSB PDB - 1K7C: Rhamnogalacturonan acetylesterase with seven N-linked carbohydrate residues distributed at two N-glycosylation...RCSB PDB - 1K7C: Rhamnogalacturonan acetylesterase with seven N-linked carbohydrate residues distributed at two N-glycosylation...

Rhamnogalacturonan acetylesterase with seven N-linked carbohydrate residues distributed at two N-glycosylation sites refined at ... Rhamnogalacturonan acetylesterase, a member of the SGNH-hydrolase family.. Molgaard, A.. () TO BE PUBLISHED --: -- ... Rhamnogalacturonan acetylesterase elucidates the structure and function of a new family of hydrolases.. Molgaard, A.,Kauppinen ... Rhamnogalacturonan acetylesterase with seven N-linked carbohydrate residues distributed at two N-glycosylation sites refined at ...
more infohttps://www.rcsb.org/structure/1k7c

Characterization of a sialate O-acetyl esterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid...Characterization of a sialate O-acetyl esterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid...

Characterization of a sialate O-acetyl esterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid ... In summary, we have characterized a novel sialate-O-acetylesterase that contributes to siallobiology of this important human ... Characterization of a sialate O-acetyl esterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid ... Characterization of a sialate O-acetyl esterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid ...
more infohttp://www.biochemj.org/content/early/2015/09/16/BJ20150388

Detection of a Cephalosporin C Acetyl Esterase in the Carbamat...Detection of a Cephalosporin C Acetyl Esterase in the Carbamat...

The possible role of a cephalosporin C acetyl esterase in the formation of the β-lactam antibiotic A16886A, 7-(5-amino-5- ... Detection of a Cephalosporin C Acetyl Esterase in the Carbamate Cephalosporin Antibiotic-Producing Culture, Streptomyces ...
more infohttps://www.mysciencework.com/publication/show/detection-of-a-cephalosporin-c-acetyl-esterase-in-the-carbamate-cephalosporin-antibiotic-producing-culture-streptomyces-clavuligerus

SWISS-MODEL Template Library | 1dex.1SWISS-MODEL Template Library | 1dex.1

RHAMNOGALACTURONAN ACETYLESTERASE FROM ASPERGILLUS ACULEATUS AT 1.9 A RESOLUTION ... RHAMNOGALACTURONAN ACETYLESTERASE FROM ASPERGILLUS ACULEATUS AT 1.9 A RESOLUTION. Coordinates. PDB Format Method. X-RAY ... Molgaard, A. et al., Rhamnogalacturonan acetylesterase elucidates the structure and function of a new family of hydrolases. ...
more infohttps://swissmodel.expasy.org/templates/1dex

Structural and functional properties of pectin and lignin-carbohydrate complexes de-esterases: a review | Springer for Research...Structural and functional properties of pectin and lignin-carbohydrate complexes de-esterases: a review | Springer for Research...

Thus, rhamnogalacturonan acetyl esterase belonging to CE-12 family has gained significance in deacetylation of these residues ... Rhamnogalacturonan acetylesterase flavodoxin-like (SGNH hydrolase). Rhamnogalacturonan present in the cell walls. RGAE ... Mølgaard A, Kauppinen S, Larsen S (2000) Rhamnogalacturonan acetylesterase elucidates the structure and function of a new ... The three-dimensional structure of the rhamnogalacturonan acetylesterase (RGAE) from Aspergillus aculeatus was revealed by ( ...
more infohttps://rd.springer.com/article/10.1186%2Fs40643-018-0230-8

What is Esterase?What is Esterase?

What is Acetylesterase?. Acetylesterase is an enzyme that catalyzes the chemical reaction ...
more infohttp://www.innovateus.net/health/what-esterase

Enzyme Explorer Assay Library | Sigma-AldrichEnzyme Explorer Assay Library | Sigma-Aldrich

Acetylesterase. 3.1.1.6. α-N-Acetylgalactosaminidase. 3.2.1.49. β-N-Acetylglucosaminidase 3.2.1.30. ...
more infohttps://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/learning-center/assay-library.html

SGNH hydrolase-type esterase domain (IPR013830) | InterPro | EMBL-EBISGNH hydrolase-type esterase domain (IPR013830) | InterPro | EMBL-EBI

Rhamnogalacturonan acetylesterase elucidates the structure and function of a new family of hydrolases.. Structure 8 373-83 2000 ... A branched N-linked glycan at atomic resolution in the 1.12 A structure of rhamnogalacturonan acetylesterase.. Acta Crystallogr ... fungal rhamnogalacturonan acetylesterase [PMID: 11752785]; and the multifunctional enzyme thioesterase I (TAP) from Escherichia ...
more infohttp://www.ebi.ac.uk/interpro/entry/IPR013830

Glycotechnology and glycoprofiling tools - NewsGlycotechnology and glycoprofiling tools - News

As part of this work, we used acetyl esterase (sialate-O-acetylesterase) to remove 9-, 8- and 7-O-acetyl groups from the EPO ... Characterisation of glycosylation in EPO using acetyl esterase. Oxford, July 2017. A paper entitled "Analysis of three epoetin ... Panel of exoglycosidases (including O-acetyl esterase, range of sialidases, galactosidases, fucosidase and mannosidases) that ...
more infohttps://ludger.com/news/index.php

CES1 carboxylesterase 1 [Homo sapiens (human)] - Gene - NCBICES1 carboxylesterase 1 [Homo sapiens (human)] - Gene - NCBI

Aes; Acetyl esterase/lipase [Lipid transport and metabolism]. pfam00135. Location:24 → 547. COesterase; Carboxylesterase family ... Aes; Acetyl esterase/lipase [Lipid transport and metabolism]. pfam00135. Location:25 → 548. COesterase; Carboxylesterase family ... Aes; Acetyl esterase/lipase [Lipid transport and metabolism]. pfam00135. Location:24 → 546. COesterase; Carboxylesterase family ... Aes; Acetyl esterase/lipase [Lipid transport and metabolism]. pfam00135. Location:25 → 547. COesterase; Carboxylesterase family ...
more infohttps://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=1066

HE - Hemagglutinin-esterase precursor - Human coronavirus OC43 (HCoV-OC43) - HE gene & proteinHE - Hemagglutinin-esterase precursor - Human coronavirus OC43 (HCoV-OC43) - HE gene & protein

sialate O-acetylesterase activity Source: UniProtKB. View the complete GO annotation on QuickGO ... ...
more infohttp://www.uniprot.org/uniprot/P30215

UniProt: A0A0R0D5D4 9GAMMUniProt: A0A0R0D5D4 9GAMM

DR GO; GO:0001681; F:sialate O-acetylesterase activity; IEA:InterPro. DR Gene3D; 2.60.120.260; -; 1. DR Gene3D; 3.40.50.1110 ... DE SubName: Full=9-O-acetylesterase {ECO:0000313,EMBL:KRG72456.1}; GN ORFNames=ABB27_00785 {ECO:0000313,EMBL:KRG72456.1}; OS ...
more infohttps://www.genome.jp/dbget-bin/www_bget?uniprot:A0A0R0D5D4_9GAMM

UniProt: A0A0S8HR61 9BACEUniProt: A0A0S8HR61 9BACE

DR PATRIC; fig,1703353.3.peg.3997; -. DR GO; GO:0001681; F:sialate O-acetylesterase activity; IEA:InterPro. DR Gene3D; 2.60. ...
more infohttps://www.genome.jp/dbget-bin/www_bget?uniprot:A0A0S8HR61_9BACE

Human Metabolome Database: HMDB0000042 (Acetic acid) Protein AssociationsHuman Metabolome Database: HMDB0000042 (Acetic acid) Protein Associations

Sialate O-acetylesterase. Q9HAT2 SIAE. 11q24. Enzyme. Not Available. HMDBP00541. Aldehyde dehydrogenase family 3 member B2. ...
more infohttp://www.hmdb.ca/metabolites/HMDB0000042/metabolite_protein_links

Human Metabolome Database: Showing metabocard for N-Acetylneuraminic acid (HMDB0000230)Human Metabolome Database: Showing metabocard for N-Acetylneuraminic acid (HMDB0000230)

7. Sialate O-acetylesterase. General function:. Involved in sialate O-acetylesterase activity. Specific function:. Catalyzes ...
more infohttp://www.hmdb.ca/metabolites/HMDB0000230
  • In this study we performed bioinformatic and biochemical characterization of a putative sialate-O-acetylesterase from T. forsythia (NanS), which contains two putative SGNH-hydrolase domains related to sialate-O-acetylesterases from a range of organisms. (biochemj.org)
  • In summary, we have characterized a novel sialate-O-acetylesterase that contributes to siallobiology of this important human pathogen and has potential applications in analysis of sialic acid diacetylation of biologics in the pharmaceutical industry. (biochemj.org)
  • In enzymology, an acetylesterase (EC 3.1.1.6) is an enzyme that catalyzes the chemical reaction an acetic ester + H2O ⇌ {\displaystyle \rightleftharpoons } an alcohol + acetate Thus, the two substrates of this enzyme are acetic ester and H2O, whereas its two products are alcohol and acetate. (wikipedia.org)
  • Other names in common use include C-esterase (in animal tissues), acetic ester hydrolase, chloroesterase, p-nitrophenyl acetate esterase, and Citrus acetylesterase. (wikipedia.org)
  • Other names in common use include C-esterase (in animal You do not have access to view this node), acetic ester hydrolase, chloroesterase, p-nitrophenyl acetate esterase , and Citrus acetylesterase . (innovateus.net)