Encyclopedias as Topic
Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
Consumer Health Information
Acetyl Coenzyme A
C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
Biological Science Disciplines
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.
Magnetic Resonance Spectroscopy
Catalogs as Topic
Quality of Life
Diagnostic Techniques and Procedures
Postural Orthostatic Tachycardia Syndrome
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
Sodium Chloride Symporter Inhibitors
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Complementary combining site contact residue mutations of the anti-digoxin Fab 26-10 permit high affinity wild-type binding. (1/3)Antibody 26-10, obtained in a secondary immune response, binds digoxin with high affinity (K(a) = 1.3 x 10(10) M(-1)) because of extensive shape complementarity. We demonstrated previously that mutations of the hapten contact residue HTrp-100 to Arg (where H refers to the heavy chain) resulted in increased specificity for digoxin analogs substituted at the cardenolide 16 position. However, mutagenesis of H:CDR1 did not result in such a specificity change despite the proximity of the H:CDR1 hapten contact residue Asn-35 to the cardenolide 16 position. Here we constructed a bacteriophage-displayed library containing randomized mutations at H chain residues 30-35 in a 26-10 mutant containing Arg-100 (26-10-RRALD). Phage were selected by panning against digoxin, gitoxin (16-OH), and 16-acetylgitoxin coupled to bovine serum albumin. Clones that retained wild-type Asn at position 35 showed preferred binding to gitoxin, like the 26-10-RRALD parent. In contrast, clones containing Val-35 selected mainly on digoxin-bovine serum albumin demonstrated a shift back to wild-type specificity. Several clones containing Val-35 bound digoxin with increased affinity, approaching that of the wild type in a few instances, in contrast to the mutation Val-35 in the wild-type 26-10 background, which reduces affinity for digoxin 90-fold. It has therefore proven possible to reorder the 26-10 binding site by mutations including two major contact residues on opposite sides of the site and yet to retain high affinity for binding for digoxin. Thus, even among antibodies that have undergone affinity maturation in vivo, different structural solutions to high affinity binding may be revealed. (+info)
The effect of dietary fiber on postprandial serum digoxin concentration in man. (2/3)The postprandial digoxin concentrations in serum were measured for 4 hr by radioimmunological assay in six healthy volunteers who had received 0.8 mg beta-acetyldigoxin by the oral route. Digoxin was given together with a formula diet containing as admixture, respectively, wheat bran, microcrystalline cellulose, pectin, carrageenan, and carob seed flour. The various additions did not reduce the mean digoxin concentrations in serum. After carob seed flour, the concentrations were significantly (P less than 5%) higher, as compared to the control. After microcrystalline cellulose, pectin, and wheat bran the mean peak concentrations were reached later than in the control state. (+info)
The effect of meloxicam on the pharmacokinetics of beta-acetyl-digoxin. (3/3)The influence of multiple-dose administration of meloxicam on the pharmacokinetics of oral beta-acetyl-digoxin was studied in 12 healthy male volunteers in a randomized double-blind two-way crossover study. The primary endpoint, Cminss, was within the accepted range for bioequivalence, as were Cmaxss and AUCss. The 90% confidence interval and the point estimator of 98.7 for Cminss were within the equivalence range of 0.8-1.25. MRT and tmax were also unchanged, while the elimination rate constant was decreased slightly by 12%, which is of no therapeutic relevance. It is concluded that co-treatment with meloxicam has no effect on the pharmacokinetics of oral digoxin. (+info)
Addiction - drug
Medical information, Addiction - drug. Definition of Addiction - drug, symptoms of Addiction - drug, treatment of Addiction - drug, and prevention of Addiction - drug. Exams and Tests Addiction - drug.
Effect of Oral Meloxicam on Health and Performance of Beef Steers Relative to Bulls Castrated on Arrival at the Feedlot - PubMed
Castration in weaned calves is stressful and affects profitability by reducing ADG and increasing susceptibility to disease. This study evaluated the effect of meloxicam, a nonsteroidal anti-inflammatory drug (NSAID), on performance and health of calves received as steers compared with bull calves s …
Plasma and myocardial digoxin concentrations in patients on oral therapy. | Heart
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Makeup Revolution Eye Shadow Palettes reviews, photos filter: reviewer skin type Sensitive - Makeupalley
Makeup Revolution Eye Shadow Palettes: rated 3.2 out of 5 on MakeupAlley. See 6 member reviews and photos. filter: reviewer skin type Sensitive
Cardenolide - Wikipedia
Cardenolide is a type of steroid. Many plants contain derivatives, collectively known as cardenolides, including many in the form of cardenolide glycosides (cardenolides that contain structural groups derived from sugars). Cardenolide glycosides are often toxic; specifically, they are heart-arresting. The term derives card- heart (from Greek καρδία kardiā) and the suffix -enolide, referring to the lactone ring at C17. It should not be confused with cardanolides. Cardanolides are a class of steroids (or aglycones if viewed as cardiac glycoside constituents), and cardenolides are a subtype of this class (see MeSH D codes list). Cardenolides are C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone (specifically a butenolide) at C-17. They are aglycone constituents of cardiac glycosides and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include: acetyldigitoxins acetyldigoxins cymarine digitoxin ...
Effect of subcutaneous meloxicam on indicators of acute pain and distress after castration and branding in 2-mo-old beef calves
The aim of this study was to assess knife castration and knife castration + branding in 2-mo-old calves, and the effect of a single dose of s.c. meloxicam at mitigating pain indicators. Seventy-one Angus crossbred bull calves (128 ± 18.5 kg of BW) were used in a 3 × 2 factorial design where main factors included procedure: sham (control calves, CT; n = 23), knife (KN; n = 24) or knife + branding (BK; n = 24), and medication: single s.c. administration of lactated ringer solution (NM; n = 35) or a single dose of 0.5 mg/kg of s.c. meloxicam (M; n = 36). Physiological samples were collected at T0, 60, 90, 120, and 180 min and on days 1, 2, 3, and 7 after procedure, whereas behavioral observations were evaluated at 2 to 4 h and 1, 2, 3, and 7 days after procedure. A procedure × time effect (P , 0.01) was observed for cortisol, where KN and BK calves had greater (P ≤ 0.01) cortisol concentrations than CT calves 60 min after the procedure, whereas BK calves had the greatest (P , 0.05) cortisol ...
Avoiding erroneous serum digoxin concentrations<...
TY - JOUR. T1 - Avoiding erroneous serum digoxin concentrations. AU - Murphy, J. E.. AU - Ward, E. S.. AU - Job, M. L.. PY - 1985/12/1. Y1 - 1985/12/1. UR - http://www.scopus.com/inward/record.url?scp=0022180028&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0022180028&partnerID=8YFLogxK. M3 - Letter. C2 - 4073054. AN - SCOPUS:0022180028. VL - 42. SP - 2418. EP - 2420. JO - American Journal of Health-System Pharmacy. JF - American Journal of Health-System Pharmacy. SN - 1079-2082. IS - 11. ER - ...
Initiation digoxin therapy associated with increased mortality in AF patients - PACE-CME
AF patients starting digoxin treatment showed increased mortality, especially in the first 6 months, irrespective of the coexistence of HF, and digoxin concentrations >1.2 ng/ml should be avoided.
Lanoxin pg 0 0625 mg : Prezzo cefodox sciroppo
62.5 mcg = 0.0625 mg Example: Based on Table 5,. (0.25 mg) daily of LANOXIN Tablets, usually taken after the morning meal. If no.LANOXIN*0,0625MG 30 CPR: AZIENDA. 0,75-1,5 mg seguiti da 0,25 mg a intervalli di 6 ore fino a ottenere leffetto terapeutico ottimale o,.Mihai Gheorghiade, MD. Valsartan 80 mg bid (n = 4885) Acute MI (0.5 - 10 days). 0.5 0.8 1.0 1.2 1.4 1.6 1.8 2.0 Serum Digoxin Concentration.REAGENTI ORGANICI Descrizione (-). Digoxin DILUENTE PER ANTICORPI. R-PE 0,5 mg REPORTER LYSIS 5X BUFFER RPMI RPMI 1640 10x500 ml.LANOXIN*30CPR 0,0625MG. 2,01. una posologia di 0,0625 mg algiorno (o meno) puo essere sufficiente. Al contrario alcuni pazientipossono richiedere una dose maggiore.. 180 tablet x 0.25mg. I end up just to introduce only affords of the counting England Wales in. The dining room lanoxin you how much I worse or at least the state.lanoxin dosages. In the journal Nature Genetics, researchers from the UK and Germany describe how they found variants in the gene ASAP1 on ...
Members include: acetyldigitoxins acetyldigoxins cymarine digitoxin digitoxigenin digoxigenin digoxin medigoxin neoconvalloside ...
List of MeSH codes (D09)
... acetyldigoxins MeSH D09.408.180.261.436.500 - medigoxin MeSH D09.408.180.261.657 - lanatosides MeSH D09.408.180.261.657.200 - ...
List of MeSH codes (D04)
... acetyldigoxins MeSH D04.808.155.160.349.350 - digoxigenin MeSH D04.808.155.160.349.500 - medigoxin MeSH D04.808.155.160.861 - ... acetyldigoxins MeSH D04.808.155.580.261.436.500 - medigoxin MeSH D04.808.155.580.261.657 - lanatosides MeSH D04.808.155.580. ...
ATC code C01
C01AA01 Acetyldigitoxin C01AA02 Acetyldigoxin C01AA03 Digitalis leaves C01AA04 Digitoxin C01AA05 Digoxin C01AA06 Lanatoside C ... C01AA07 Deslanoside C01AA08 Metildigoxin C01AA09 Gitoformate C01AA52 Acetyldigoxin, combinations C01AB01 Proscillaridin C01AB51 ...
... is a cardiac glycoside. It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin. It increases ... The effects of α-acetyldigoxin begin 3-4 hours after administration, and maximize after 6-8 hours. It is prescribed for ... α-acetyldigoxin in the ChemIDplus database v t e. ...
Α-Acetyldigoxin - Wikipedia
α-Acetyldigoxin is a cardiac glycoside. It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin. It increases ... The effects of α-acetyldigoxin begin 3-4 hours after administration, and maximize after 6-8 hours. It is prescribed for ... α-acetyldigoxin in the ChemIDplus database v t e. ...
Acetyldigoxin - wikidoc
Klinische Erfahrungen über enterale Resorption und Glykosidbedarf von Digoxin und β-Acetyldigoxin | Springer for Research &...
1965) sowie Benthe und Chenpanich (1965) mit der von Haberland(1965) beschriebenen Substanz β-Acetyldigoxin ergaben eine ... 1965) sowie Benthe und Chenpanich (1965) mit der von Haberland (1965) beschriebenen Substanz β-Acetyldigoxin ergaben eine ... ermittelten bei der Katze eine enterale Resorptionsquote von 83-92% für β-Acetyldigoxin. Die ersten klinischen Berichte von ... Hilger H.H. (1973) Klinische Erfahrungen über enterale Resorption und Glykosidbedarf von Digoxin und β-Acetyldigoxin. In: ...
Vergleich der enteralen Resorption des Digoxins und des β-Acetyldigoxins mit Hilfe des Elektrokardiogramms | Springer for...
Zur Bestimmung der Resorption von β-Acetyldigoxin haben wir Untersuchungen in Anlehnung an eine von Gold(1942) angegebene ... Zur Bestimmung der Resorption von β-Acetyldigoxin haben wir Untersuchungen in Anlehnung an eine von Gold (1942) angegebene ... Kast G. (1973) Vergleich der enteralen Resorption des Digoxins und des β-Acetyldigoxins mit Hilfe des Elektrokardiogramms. In: ... Vergleich der enteralen Resorption des Digoxins und des β-Acetyldigoxins mit Hilfe des Elektrokardiogramms. ...
Formulierungsprobleme ausgewählter Arzneiformen mit β-Acetyldigoxin - Research Collection
HERZMITTEL + KREISLAUFMITTEL (PHARMAZIE); GLYKOSIDE (BIOCHEMIE); ASPARAGIN, ASPARAGINSÄURE, ASPARTAT (BIOCHEMIE); ARZNEIMITTELSTABILITÄT + ARZNEIMITTELZERSETZUNG; HERZGLYKOSIDE + DIGITALISGLYKOSIDE (PHARMAZIE); CARDIAC DRUGS + CARDIOVASCULAR DRUGS (PHARMACY); GLYCOSIDES (BIOCHEMISTRY); ASPARAGINE, ASPARTIC ACID, ASPARTATE (BIOCHEMISTRY); DRUG STABILITY + DRUG DEGRADATION (PHARMACIE); CARDENOLIDES + DIGITALIS GLYCOSIDES (PHARMACY ...
Synthesis Of Drugs: Laboratory Synthesis Of alpha Acetyl Digoxin
tags-synthesis of drugs,method of preparation of Acetyl Digoxin,molecular weight Acetyl Digoxin , molecular formula of Acetyl ... alpha Acetyl Digoxin Use: cardiotonic, cardiac glycoside. alpha Acetyl Digoxin LD50: 3300 mg/kg (g. p., p.o.);200 mg/kg (cat, p ... alpha Acetyl Digoxin MW: 822.99. alpha Acetyl DigoxinMF: C43H66O15. ...
ß-Acetyldigoxin for peak identification (Y0000642) | CAS 5355-48-6 | CLEARSYNTH
... ß-Acetyldigoxin for peak identification (Y0000642). Purchase ß-Acetyldigoxin for peak identification (Y0000642) online ... ß-Acetyldigoxin for peak identification (Y0000642). EP STANDARDS Availability: Compound under re-stock / certification. Please ... Do you want a quotation or have a question about ß-Acetyldigoxin for peak identification (Y0000642) ? We normally respond ...
b-Acetyl digoxin (CAS 5355-48-6) | Glentham Life Sciences
Moduretic 5-50 Advanced Patient Information - Drugs.com
Metolazone (Oral Route) Proper Use - Mayo Clinic
Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, check with your doctor .. Drinking alcoholic beverages may also make the dizziness, lightheadedness, or fainting worse. While you are taking this medicine, be careful to limit the amount of alcohol you drink .. This medicine may cause changes in your blood sugar levels. If you notice a change in the results of your blood or urine sugar tests or if you have any questions, check with your doctor .. Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests (e.g., tests for parathyroid function) may be affected by this medicine .. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements .. ...
Deconamine SR Advanced Patient Information - Drugs.com
Acebutolol (Oral Route) Proper Use - Mayo Clinic
Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well .. Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease .. Do not interrupt or stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. Some conditions may become worse when the medicine is stopped suddenly, which can be dangerous .. ...
Pharmacokinetic Drug Interaction Profiles of Proton Pump Inhibitors: An Update | SpringerLink
Phase 1 Study of Digoxin for Congenital Polycythemia Due to Up-Regulated Hypoxia Sensing
Calcium gluconate - DrugBank
Aminoglutethimide - DrugBank
Difference between revisions of "The WikiDoc Living Textbook of Cardiology" - wikidoc
Cardenolide - Wikipedia
DIG Antibody (400-001-MG2)
ABC of oral bioavailability: transporters as gatekeepers in the gut | Gut
Hydralazine and hydrochlorothiazide (Oral route)
However, it is best to plan your dose or doses according to a schedule that will least affect your personal activities and sleep. Ask your health care professional to help you plan the best time to take this medicine. In addition to the use of the medicine your doctor has prescribed, treatment for your high blood pressure may include weight control and care in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Remember that this medicine will not cure your high blood pressure but it does help control it. Therefore, you must continue to take it as directed if you expect to lower your blood pressure and ...
Valsartan and hydrochlorothiazide (Oral route)
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects. Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away. This medicine may cause dizziness, lightheadedness, or fainting, especially when you get up suddenly from a lying or sitting position. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. If you faint, call your doctor right away. Check with your doctor right away if you become sick while taking this medicine, especially if you have severe nausea, vomiting, ...
GMS | 17th Annual Meeting of the German Drug Utilisation Research Group (GAA) | Potentially inappropriate medication in two...
aliskiren and hydrochlorothiazide - patient information, description, dosage and directions.
DailyMed - MELOXICAM tablet
Mobic (Meloxicam): Uses, Dosage, Side Effects, Interactions, Warning
1 - Forex waluty kursy
- It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin. (wikipedia.org)
- 1965) sowie Benthe und Chenpanich (1965) mit der von Haberland (1965) beschriebenen Substanz β-Acetyldigoxin ergaben eine wesentlich bessere enterale Resorption dieses neuen Herzglykosids gegenüber unverestertem Digoxin und eine etwa gleich hohe enterale Resorptionsquote wie bei Digitoxin. (springer.com)
- 1966) sprachen ebenfalls für eine bessere enterale Resorption von β-Acetyldigoxin im Vergleich zu unverestertem Digoxin, wiesen aber andererseits auf einen bei manchen Patienten wesentlich höheren Glykosidbedarf hin, als es rechnerisch einer 90%igen oder sogar höheren enteralen Resorptionsquote von β-Acetyldigoxin und einer Vollwirkdosis von 2,0 mg entsprechen würde. (springer.com)
- Hilger H.H. (1973) Klinische Erfahrungen über enterale Resorption und Glykosidbedarf von Digoxin und β-Acetyldigoxin. (springer.com)
- Members include: acetyldigitoxins acetyldigoxins cymarine digitoxin digitoxigenin digoxigenin digoxin medigoxin neoconvalloside ouabain strophanthins strophanthidin Bufadienolide and Marinobufagenin are similar in structure and function. (wikipedia.org)
- Aceclofenac Acemetacin Acetyldigoxin Alacepril Amphetamine Amtolmetin Guacil Arginine Arsenic Trioxide proscar Aspirin Benazepril Benzphetamine Bromfenac Bufexamac Captopril Celecoxib Choline Salicylate Cilazapril Clonixin Cyclophosphamide Delapril Deslanoside Dexibuprofen Dexketoprofen Dextroamphetamine Diclofenac Diflunisal Digitalis Digitoxin Digoxin Dipyrone Dofetilide Droperidol Droxicam Enalaprilat Enalapril Maleate Etodolac Etofenamate Etoricoxib. (heroesforhire.info)
- Reversible decreases in steady-state plasma digoxin and renal glycoside excretion were observed in patients receiving beta-acetyldigoxin and chemotherapy regimens containing cyclophosphamide, vincristine, and prednisone with or without cytarabine or procarbazine. (israelpharma.com)
- Digitalis lanata describióse por Jakob Friedrich Ehrhart y espublizóse en Beiträge zur Naturkunde 7: 152â 153. (indiakhelega.com)
- Its corresponding aglycone is digoxigenin, and its acetyl derivative is acetyldigoxin. (thermofisher.com)
- α-Acetyldigoxin is a cardiac glycoside. (wikipedia.org)
- Patients of the Stroke-cohort used acetyldigoxin, piracetam, and amitriptylin most frequently (11%, 10%, 7% of all PIM respectively). (egms.de)
- Lanatoside-C or Acetyldigoxin the cancer incidence was not just a little low when one was on these drugs, it was very, very much lower. (spacedoc.com)
- Mosby's Dental Dictionary - E-Book - Google Books Result (https://books.google.com.ua/books?id=hQejBQAAQBAJ&a mp;pg=PA64&lpg=PA64&dq=azelex+drug+class&am p;source=bl&ots=HEvYmz5BOt&sig=36OQ3FRTk-Y9 jFF-IROtoOi7jRE&hl=en&sa=X&ved=0ahUKEwj LlrPwloTYAhWEYJoKHfZUC20Q6AEIfTAS) Generally there is only one axon to a cell. (discounteru.com)