Digoxin: A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)Acetyl Coenzyme A: Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.Digitoxin: A cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)Cardenolides: C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.Cardiotonic Agents: Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).Molecular Weight: The sum of the weight of all the atoms in a molecule.Proteomics: The systematic study of the complete complement of proteins (PROTEOME) of organisms.Fermentation: Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.Streptomyces: A genus of bacteria that form a nonfragmented aerial mycelium. Many species have been identified with some being pathogenic. This genus is responsible for producing a majority of the ANTI-BACTERIAL AGENTS of practical value.Medigoxin: A semisynthetic digitalis glycoside with the general properties of DIGOXIN but more rapid onset of action. Its cardiotonic action is prolonged by its demethylation to DIGOXIN in the liver. It has been used in the treatment of congestive heart failure (HEART FAILURE).Drug Information Services: Services providing pharmaceutic and therapeutic drug information and consultation.Pamphlets: Printed publications usually having a format with no binding and no cover and having fewer than some set number of pages. They are often devoted to a single subject.Drug Labeling: Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.Patient Education as Topic: The teaching or training of patients concerning their own health needs.Formularies as Topic: Works about lists of drugs or collections of recipes, formulas, and prescriptions for the compounding of medicinal preparations. Formularies differ from PHARMACOPOEIAS in that they are less complete, lacking full descriptions of the drugs, their formulations, analytic composition, chemical properties, etc. In hospitals, formularies list all drugs commonly stocked in the hospital pharmacy.Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Medical Records Systems, Computerized: Computer-based systems for input, storage, display, retrieval, and printing of information contained in a patient's medical record.Advertising as Topic: The act or practice of calling public attention to a product, service, need, etc., especially by paid announcements in newspapers, magazines, on radio, or on television. (Random House Unabridged Dictionary, 2d ed)Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Therapeutic Equivalency: The relative equivalency in the efficacy of different modes of treatment of a disease, most often used to compare the efficacy of different pharmaceuticals to treat a given disease.Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.Sodium Chloride Symporter Inhibitors: Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA.Diuretics: Agents that promote the excretion of urine through their effects on kidney function.Antihypertensive Agents: Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.Triamterene: A pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.Metolazone: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.Dizziness: An imprecise term which may refer to a sense of spatial disorientation, motion of the environment, or lightheadedness.Alcoholic Beverages: Drinkable liquids containing ETHANOL.Protective Devices: Devices designed to provide personal protection against injury to individuals exposed to hazards in industry, sports, aviation, or daily activities.Urine Specimen Collection: Methods or procedures used to obtain samples of URINE.Diagnostic Techniques and Procedures: Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.Postural Orthostatic Tachycardia Syndrome: A syndrome of ORTHOSTATIC INTOLERANCE combined with excessive upright TACHYCARDIA, and usually without associated ORTHOSTATIC HYPOTENSION. All variants have in common an excessively reduced venous return to the heart (central HYPOVOLEMIA) while upright.Beverages: Liquids that are suitable for drinking. (From Merriam Webster Collegiate Dictionary, 10th ed)Nonprescription Drugs: Medicines that can be sold legally without a DRUG PRESCRIPTION.Parathyroid Glands: Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.Fusion Proteins, bcr-abl: Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. Several different variants of the bcr-abl fusion proteins occur depending upon the precise location of the chromosomal breakpoint. These variants can be associated with distinct subtypes of leukemias such as PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; and NEUTROPHILIC LEUKEMIA, CHRONIC.Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.Benzamides: BENZOIC ACID amides.Pyrimidines: A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.PiperazinesPyridazinesProtein-Tyrosine Kinases: Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.Protein Kinase Inhibitors: Agents that inhibit PROTEIN KINASES.Databases, Pharmaceutical: Databases devoted to knowledge about PHARMACEUTICAL PRODUCTS.K562 Cells: An ERYTHROLEUKEMIA cell line derived from a CHRONIC MYELOID LEUKEMIA patient in BLAST CRISIS.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Posture: The position or attitude of the body.Valine: A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.TetrazolesTreatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.Pharmaceutical Services, Online: Pharmacy services accessed via electronic means.Counterfeit Drugs: Drugs manufactured and sold with the intent to misrepresent its origin, authenticity, chemical composition, and or efficacy. Counterfeit drugs may contain inappropriate quantities of ingredients not listed on the label or package. In order to further deceive the consumer, the packaging, container, or labeling, may be inaccurate, incorrect, or fake.Legislation, Pharmacy: Laws and regulations, pertaining to the field of pharmacy, proposed for enactment or enacted by a legislative body.Pharmacies: Facilities for the preparation and dispensing of drugs.Prescription Drugs: Drugs that cannot be sold legally without a prescription.Drug and Narcotic Control: Control of drug and narcotic use by international agreement, or by institutional systems for handling prescribed drugs. This includes regulations concerned with the manufacturing, dispensing, approval (DRUG APPROVAL), and marketing of drugs.Commerce: The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)Adrenergic beta-Antagonists: Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.Australia: The smallest continent and an independent country, comprising six states and two territories. Its capital is Canberra.
(1/3) Complementary combining site contact residue mutations of the anti-digoxin Fab 26-10 permit high affinity wild-type binding.

Antibody 26-10, obtained in a secondary immune response, binds digoxin with high affinity (K(a) = 1.3 x 10(10) M(-1)) because of extensive shape complementarity. We demonstrated previously that mutations of the hapten contact residue HTrp-100 to Arg (where H refers to the heavy chain) resulted in increased specificity for digoxin analogs substituted at the cardenolide 16 position. However, mutagenesis of H:CDR1 did not result in such a specificity change despite the proximity of the H:CDR1 hapten contact residue Asn-35 to the cardenolide 16 position. Here we constructed a bacteriophage-displayed library containing randomized mutations at H chain residues 30-35 in a 26-10 mutant containing Arg-100 (26-10-RRALD). Phage were selected by panning against digoxin, gitoxin (16-OH), and 16-acetylgitoxin coupled to bovine serum albumin. Clones that retained wild-type Asn at position 35 showed preferred binding to gitoxin, like the 26-10-RRALD parent. In contrast, clones containing Val-35 selected mainly on digoxin-bovine serum albumin demonstrated a shift back to wild-type specificity. Several clones containing Val-35 bound digoxin with increased affinity, approaching that of the wild type in a few instances, in contrast to the mutation Val-35 in the wild-type 26-10 background, which reduces affinity for digoxin 90-fold. It has therefore proven possible to reorder the 26-10 binding site by mutations including two major contact residues on opposite sides of the site and yet to retain high affinity for binding for digoxin. Thus, even among antibodies that have undergone affinity maturation in vivo, different structural solutions to high affinity binding may be revealed.  (+info)

(2/3) The effect of dietary fiber on postprandial serum digoxin concentration in man.

The postprandial digoxin concentrations in serum were measured for 4 hr by radioimmunological assay in six healthy volunteers who had received 0.8 mg beta-acetyldigoxin by the oral route. Digoxin was given together with a formula diet containing as admixture, respectively, wheat bran, microcrystalline cellulose, pectin, carrageenan, and carob seed flour. The various additions did not reduce the mean digoxin concentrations in serum. After carob seed flour, the concentrations were significantly (P less than 5%) higher, as compared to the control. After microcrystalline cellulose, pectin, and wheat bran the mean peak concentrations were reached later than in the control state.  (+info)

(3/3) The effect of meloxicam on the pharmacokinetics of beta-acetyl-digoxin.

The influence of multiple-dose administration of meloxicam on the pharmacokinetics of oral beta-acetyl-digoxin was studied in 12 healthy male volunteers in a randomized double-blind two-way crossover study. The primary endpoint, Cminss, was within the accepted range for bioequivalence, as were Cmaxss and AUCss. The 90% confidence interval and the point estimator of 98.7 for Cminss were within the equivalence range of 0.8-1.25. MRT and tmax were also unchanged, while the elimination rate constant was decreased slightly by 12%, which is of no therapeutic relevance. It is concluded that co-treatment with meloxicam has no effect on the pharmacokinetics of oral digoxin.  (+info)

*  Cardenolide
Members include: acetyldigitoxins acetyldigoxins cymarine digitoxin digitoxigenin digoxigenin digoxin medigoxin neoconvalloside ...
*  Α-Acetyldigoxin
... is a cardiac glycoside. It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin. Its positive ...
*  List of MeSH codes (D09)
... acetyldigoxins MeSH D09.408.180.261.436.500 --- medigoxin MeSH D09.408.180.261.657 --- lanatosides MeSH D09.408.180.261.657.200 ...
*  List of MeSH codes (D04)
... acetyldigoxins MeSH D04.808.155.160.349.350 --- digoxigenin MeSH D04.808.155.160.349.500 --- medigoxin MeSH D04.808.155.160.861 ... acetyldigoxins MeSH D04.808.155.580.261.436.500 --- medigoxin MeSH D04.808.155.580.261.657 --- lanatosides MeSH D04.808.155.580 ...
*  ATC code C01
C01AA01 Acetyldigitoxin C01AA02 Acetyldigoxin C01AA03 Digitalis leaves C01AA04 Digitoxin C01AA05 Digoxin C01AA06 Lanatoside C ... C01AA07 Deslanoside C01AA08 Metildigoxin C01AA09 Gitoformate C01AA52 Acetyldigoxin, combinations C01AB01 Proscillaridin C01AB51 ...
Α-Acetyldigoxin - Wikipedia  Α-Acetyldigoxin - Wikipedia
α-Acetyldigoxin is a cardiac glycoside. It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin. Its positive ...
more infohttps://en.wikipedia.org/wiki/%CE%91-Acetyldigoxin
Vergleich der enteralen Resorption des Digoxins und des β-Acetyldigoxins mit Hilfe des Elektrokardiogramms | Springer for...  Vergleich der enteralen Resorption des Digoxins und des β-Acetyldigoxins mit Hilfe des Elektrokardiogramms | Springer for...
Zur Bestimmung der Resorption von β-Acetyldigoxin haben wir Untersuchungen in Anlehnung an eine von Gold(1942) angegebene ... Zur Bestimmung der Resorption von β-Acetyldigoxin haben wir Untersuchungen in Anlehnung an eine von Gold (1942) angegebene ... Kast G. (1973) Vergleich der enteralen Resorption des Digoxins und des β-Acetyldigoxins mit Hilfe des Elektrokardiogramms. In: ... Vergleich der enteralen Resorption des Digoxins und des β-Acetyldigoxins mit Hilfe des Elektrokardiogramms. ...
more infohttps://rd.springer.com/chapter/10.1007/978-3-642-72296-7_28
Klinische Erfahrungen über enterale Resorption und Glykosidbedarf von Digoxin und β-Acetyldigoxin | Springer for Research &...  Klinische Erfahrungen über enterale Resorption und Glykosidbedarf von Digoxin und β-Acetyldigoxin | Springer for Research &...
1965) sowie Benthe und Chenpanich (1965) mit der von Haberland(1965) beschriebenen Substanz β-Acetyldigoxin ergaben eine ... 1965) sowie Benthe und Chenpanich (1965) mit der von Haberland (1965) beschriebenen Substanz β-Acetyldigoxin ergaben eine ... ermittelten bei der Katze eine enterale Resorptionsquote von 83-92% für β-Acetyldigoxin. Die ersten klinischen Berichte von ... Hilger H.H. (1973) Klinische Erfahrungen über enterale Resorption und Glykosidbedarf von Digoxin und β-Acetyldigoxin. In: ...
more infohttps://rd.springer.com/chapter/10.1007/978-3-642-72296-7_31
Formulierungsprobleme ausgewählter Arzneiformen mit β-Acetyldigoxin - Research Collection  Formulierungsprobleme ausgewählter Arzneiformen mit β-Acetyldigoxin - Research Collection
HERZMITTEL + KREISLAUFMITTEL (PHARMAZIE); GLYKOSIDE (BIOCHEMIE); ASPARAGIN, ASPARAGINSÄURE, ASPARTAT (BIOCHEMIE); ARZNEIMITTELSTABILITÄT + ARZNEIMITTELZERSETZUNG; HERZGLYKOSIDE + DIGITALISGLYKOSIDE (PHARMAZIE); CARDIAC DRUGS + CARDIOVASCULAR DRUGS (PHARMACY); GLYCOSIDES (BIOCHEMISTRY); ASPARAGINE, ASPARTIC ACID, ASPARTATE (BIOCHEMISTRY); DRUG STABILITY + DRUG DEGRADATION (PHARMACIE); CARDENOLIDES + DIGITALIS GLYCOSIDES (PHARMACY ...
more infohttps://www.research-collection.ethz.ch/handle/20.500.11850/137937
Synthesis Of Drugs: Laboratory Synthesis Of alpha Acetyl Digoxin  Synthesis Of Drugs: Laboratory Synthesis Of alpha Acetyl Digoxin
tags-synthesis of drugs,method of preparation of Acetyl Digoxin,molecular weight Acetyl Digoxin , molecular formula of Acetyl ... alpha Acetyl Digoxin Use: cardiotonic, cardiac glycoside. alpha Acetyl Digoxin LD50: 3300 mg/kg (g. p., p.o.);200 mg/kg (cat, p ... alpha Acetyl Digoxin MW: 822.99. alpha Acetyl DigoxinMF: C43H66O15. ...
more infohttp://drugsynthesis.blogspot.com/2011/11/laboratory-synthesis-of-alpha-acetyl.html
Moduretic 5-50 Advanced Patient Information - Drugs.com  Moduretic 5-50 Advanced Patient Information - Drugs.com
Detailed drug Information for Moduretic 5-50. Includes common brand names, drug descriptions, warnings, side effects and dosing information.
more infohttps://www.drugs.com/cons/moduretic-5-50.html
Hydralazine and hydrochlorothiazide Advanced Patient Information - Drugs.com  Hydralazine and hydrochlorothiazide Advanced Patient Information - Drugs.com
Detailed drug Information for hydralazine and hydrochlorothiazide. Includes common brand names, drug descriptions, warnings, side effects and dosing information.
more infohttps://www.drugs.com/cons/hydralazine-and-hydrochlorothiazide.html
Metolazone (Oral Route) Proper Use - Mayo Clinic  Metolazone (Oral Route) Proper Use - Mayo Clinic
Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, check with your doctor .. Drinking alcoholic beverages may also make the dizziness, lightheadedness, or fainting worse. While you are taking this medicine, be careful to limit the amount of alcohol you drink .. This medicine may cause changes in your blood sugar levels. If you notice a change in the results of your blood or urine sugar tests or if you have any questions, check with your doctor .. Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests (e.g., tests for parathyroid function) may be affected by this medicine .. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements .. ...
more infohttps://www.mayoclinic.org/drugs-supplements/metolazone-oral-route/proper-use/DRG-20071743?p=1
Captopril And Hydrochlorothiazide (Oral Route) Description and Brand Names - Mayo Clinic  Captopril And Hydrochlorothiazide (Oral Route) Description and Brand Names - Mayo Clinic
Stop using this medicine and call your doctor right away if you have swelling of the face, arms, legs, eyes, lips, or tongue, or problems with swallowing or breathing. These are symptoms of a condition called angioedema .. Stop using this medicine and call your doctor right away if you have severe stomach pain. This could be a symptom of a condition called intestinal angioedema .. Tell your doctor immediately if you have any signs of infection such as chills, sore throat, or fever. These may be symptoms of an immune system condition called neutropenia .. If your symptoms do not improve within a few days or if they become worse, check with your doctor. Do not stop using this medicine unless your doctor tells you to .. You may experience lightheadedness during the first few days with this medicine. If this becomes severe and you faint, stop using this medicine and talk to your doctor right away .. This medicine may affect blood sugar levels. If you notice a change in the results of your blood or ...
more infohttps://www.mayoclinic.org/drugs-supplements/captopril-and-hydrochlorothiazide-oral-route/description/drg-20069172?p=1
Pharmacokinetic Drug Interaction Profiles of Proton Pump Inhibitors: An Update | SpringerLink  Pharmacokinetic Drug Interaction Profiles of Proton Pump Inhibitors: An Update | SpringerLink
... β-acetyldigoxin [91], ethanol [92], glibenclamide [93], levothyroxine sodium [94], metoprolol [95], naproxen [96], sustained- ...
more infohttps://link.springer.com/article/10.1007%2Fs40264-014-0144-0
Triptorelin - DrugBank  Triptorelin - DrugBank
Acetyldigoxin. Acetyldigoxin may decrease the cardiotoxic activities of Triptorelin.. AICA ribonucleotide. The therapeutic ...
more infohttps://www.drugbank.ca/drugs/DB06825
Ponatinib - DrugBank  Ponatinib - DrugBank
Acetyldigoxin. Acetyldigoxin may decrease the cardiotoxic activities of Ponatinib.. Experimental. Afatinib. The serum ...
more infohttps://www.drugbank.ca/drugs/DB08901
WHOCC - ATC/DDD Index  WHOCC - ATC/DDD Index
acetyldigoxin 0.5 mg O List of abbreviations. Last updated: 2018-12-13 ...
more infohttps://www.whocc.no/atc_ddd_index/?code=C01AA02&showdescription=yes
Hydralazine and hydrochlorothiazide (Oral route)  Hydralazine and hydrochlorothiazide (Oral route)
However, it is best to plan your dose or doses according to a schedule that will least affect your personal activities and sleep. Ask your health care professional to help you plan the best time to take this medicine. In addition to the use of the medicine your doctor has prescribed, treatment for your high blood pressure may include weight control and care in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Remember that this medicine will not cure your high blood pressure but it does help control it. Therefore, you must continue to take it as directed if you expect to lower your blood pressure and ...
more infohttps://ssl.adam.com/content.aspx?productid=47&isarticlelink=false&pid=47&gid=600411&site=summithealth.adam.com&login=SUMM2111
Valsartan and hydrochlorothiazide (Oral route)  Valsartan and hydrochlorothiazide (Oral route)
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects. Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away. This medicine may cause dizziness, lightheadedness, or fainting, especially when you get up suddenly from a lying or sitting position. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. If you faint, call your doctor right away. Check with your doctor right away if you become sick while taking this medicine, especially if you have severe nausea, vomiting, ...
more infohttps://ssl.adam.com/content.aspx?productid=47&isarticlelink=false&pid=47&gid=600427&site=summithealth.adam.com&login=SUMM2111
JoDrugs. Cardiac Glycoside  JoDrugs. Cardiac Glycoside
style,#search-block .headerSearchBox{border-bottom-left-radius:3px !important;border-top-left-radius:3px !important;}.show-title-for-nojs{display:none;},/style, ,div id="search-title" class="show-title-for-nojs", ,label for="headerSearchKeyword",Drug. / Keyword,/label, ,/div ...
more infohttp://www.jodrugs.com/category/1004-cardiac-glycoside.aspx
Medical Isotopes, Inc.  Medical Isotopes, Inc.
β-Acetyl Digoxin. 1 mg. $650. Add to Cart 10 mg. $2,200. Add to Cart ...
more infohttp://www.medicalisotopes.com/display_subcategory.php?id=188
Amlodipine, valsartan, and hydrochlorothiazide (Oral route)  Amlodipine, valsartan, and hydrochlorothiazide (Oral route)
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects. Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away. Dizziness, lightheadedness, or fainting may also occur, especially when you get up from a lying or sitting position or if you have been taking a diuretic (water pill). Make sure you know how you react to the medicine before you drive, use machines, or do other things that could be dangerous if you are dizzy or not alert. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. If you faint, call your doctor right away. Check with your doctor right away if you become sick while taking this medicine, ...
more infohttps://www.allinahealth.org/CCS/doc/Thomson%20Detailed%20Drugs/47/602957.htm
ATC code C01  ATC code C01
C01AA02 Acetyldigoxin C01AA03 Digitalis leaves C01AA04 Digitoxin C01AA05 Digoxin C01AA06 Lanatoside C C01AA07 Deslanoside ... C01AA52 Acetyldigoxin, combinations C01AB Scilla glycosides. C01AB01 Proscillaridin C01AB51 Proscillaridin, combinations C01AC ...
more infohttp://www.chemeurope.com/en/encyclopedia/ATC_code_C01.html
  • It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin. (wikipedia.org)
  • 1965) sowie Benthe und Chenpanich (1965) mit der von Haberland (1965) beschriebenen Substanz β-Acetyldigoxin ergaben eine wesentlich bessere enterale Resorption dieses neuen Herzglykosids gegenüber unverestertem Digoxin und eine etwa gleich hohe enterale Resorptionsquote wie bei Digitoxin. (springer.com)
  • 1966) sprachen ebenfalls für eine bessere enterale Resorption von β-Acetyldigoxin im Vergleich zu unverestertem Digoxin, wiesen aber andererseits auf einen bei manchen Patienten wesentlich höheren Glykosidbedarf hin, als es rechnerisch einer 90%igen oder sogar höheren enteralen Resorptionsquote von β-Acetyldigoxin und einer Vollwirkdosis von 2,0 mg entsprechen würde. (springer.com)
  • Hilger H.H. (1973) Klinische Erfahrungen über enterale Resorption und Glykosidbedarf von Digoxin und β-Acetyldigoxin. (springer.com)
  • Members include: acetyldigitoxins acetyldigoxins cymarine digitoxin digitoxigenin digoxigenin digoxin medigoxin neoconvalloside ouabain strophanthins strophanthidin Bufadienolide and Marinobufagenin are similar in structure and function. (wikipedia.org)