Dictionaries, ChemicalAgrochemicals: Chemicals used in agriculture. These include pesticides, fumigants, fertilizers, plant hormones, steroids, antibiotics, mycotoxins, etc.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Biopharmaceutics: The study of the physical and chemical properties of a drug and its dosage form as related to the onset, duration, and intensity of its action.Pharmaceutical Preparations: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.Acetonitriles: Compounds in which a methyl group is attached to the cyano moiety.Intermittent Positive-Pressure Breathing: Application of positive pressure to the inspiratory phase of spontaneous respiration.Chemical Hazard Release: Uncontrolled release of a chemical from its containment that either threatens to, or does, cause exposure to a chemical hazard. Such an incident may occur accidentally or deliberately.Respiratory Protective Devices: Respirators to protect individuals from breathing air contaminated with harmful dusts, fogs, fumes, mists, gases, smokes, sprays, or vapors.Hazardous Substances: Elements, compounds, mixtures, or solutions that are considered severely harmful to human health and the environment. They include substances that are toxic, corrosive, flammable, or explosive.National Institute for Occupational Safety and Health (U.S.): An institute of the CENTERS FOR DISEASE CONTROL AND PREVENTION which is responsible for assuring safe and healthful working conditions and for developing standards of safety and health. Research activities are carried out pertinent to these goals.Positive-Pressure Respiration: A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange.Intermittent Positive-Pressure Ventilation: Application of positive pressure to the inspiratory phase when the patient has an artificial airway in place and is connected to a ventilator.Pharmacopoeias as Topic: Authoritative treatises on drugs and preparations, their description, formulation, analytic composition, physical constants, main chemical properties used in identification, standards for strength, purity, and dosage, chemical tests for determining identity and purity, etc. They are usually published under governmental jurisdiction (e.g., USP, the United States Pharmacopoeia; BP, British Pharmacopoeia; P. Helv., the Swiss Pharmacopoeia). They differ from FORMULARIES in that they are far more complete: formularies tend to be mere listings of formulas and prescriptions.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Drug Approval: Process that is gone through in order for a drug to receive approval by a government regulatory agency. This includes any required pre-clinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance of the drug.Solvents: Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)Distillation: A chemical process for separating the components of a liquid mixture by boiling and collecting condensed vapors.Atmospheric Pressure: The pressure at any point in an atmosphere due solely to the weight of the atmospheric gases above the point concerned.Steam: Water in its gaseous state. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Oils, Volatile: Oils which evaporate readily. The volatile oils occur in aromatic plants, to which they give odor and other characteristics. Most volatile oils consist of a mixture of two or more TERPENES or of a mixture of an eleoptene (the more volatile constituent of a volatile oil) with a stearopten (the more solid constituent). The synonym essential oils refers to the essence of a plant, as its perfume or scent, and not to its indispensability.Formularies as Topic: Works about lists of drugs or collections of recipes, formulas, and prescriptions for the compounding of medicinal preparations. Formularies differ from PHARMACOPOEIAS in that they are less complete, lacking full descriptions of the drugs, their formulations, analytic composition, chemical properties, etc. In hospitals, formularies list all drugs commonly stocked in the hospital pharmacy.Economics, Pharmaceutical: Economic aspects of the fields of pharmacy and pharmacology as they apply to the development and study of medical economics in rational drug therapy and the impact of pharmaceuticals on the cost of medical care. Pharmaceutical economics also includes the economic considerations of the pharmaceutical care delivery system and in drug prescribing, particularly of cost-benefit values. (From J Res Pharm Econ 1989;1(1); PharmacoEcon 1992;1(1))Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Academies and Institutes: Organizations representing specialized fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., National Academy of Sciences, Brookings Institution, etc.Security Measures: Regulations to assure protection of property and equipment.Legislation, Food: Laws and regulations concerned with industrial processing and marketing of foods.Cephalotaxus: A plant genus of the family Cephalotaxaceae, order Pinales, class Pinopsida, division CONIFEROPHYTA. Members contain homoharringtonine.Harringtonines: Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkaloid cephalotaxine and may be effective as antineoplastic agents.Spiro Compounds: A group of compounds consisting in part of two rings sharing one atom (usually a carbon) in common.PyrrolidinesChemical Industry: The aggregate enterprise of manufacturing and technically producing chemicals. (From Random House Unabridged Dictionary, 2d ed)Sinorhizobium: A genus of gram-negative, aerobic, nonsporeforming rods which usually contain granules of poly-beta-hydroxybutyrate. (From Bergey's Manual of Determinative Bacteriology, 9th ed)Thiocarbamates: Carbamates in which the -CO- group has been replaced by a -CS- group.Cyanides: Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.Amines: A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)Hydrogen Cyanide: Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.Metals: Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)Hematinics: Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.Potassium Cyanide: A highly poisonous compound that is an inhibitor of many metabolic processes, but has been shown to be an especially potent inhibitor of heme enzymes and hemeproteins. It is used in many industrial processes.Benzothiazoles: Compounds with a benzene ring fused to a thiazole ring.Acrylonitrile: A highly poisonous compound used widely in the manufacture of plastics, adhesives and synthetic rubber.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.BooksPublishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.MEDLINE: The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).

Efficient nitroso group transfer from N-nitrosoindoles to nucleotides and 2'-deoxyguanosine at physiological pH. A new pathway for N-nitrosocompounds to exert genotoxicity. (1/350)

The endogenous formation of N-nitrosoindoles is of concern since humans are exposed to a variety of naturally occurring and synthetic indolic compounds. As part of a study to evaluate the genotoxicity of N-nitrosoindoles, the reactions of three model compounds with purine nucleotides and 2'-deoxyguanosine at physiological pH were investigated. The profiles of reaction products were identical for each of the N-nitrosoindoles and three distinct pathways of reaction could be discerned. These pathways were: (i) depurination to the corresponding purine bases, (ii) deamination, coupled with depurination, to give hypoxanthine and xanthine, and (iii) formation of the novel nucleotide 2'-deoxyoxanosine monophosphate and its corresponding depurination product oxanine in reactions with 2'-deoxyguanosine monophosphate. 2'-Deoxyoxanosine and oxanine were observed in reactions with 2'-deoxyguanosine. Further studies showed that formation of all of these products could be rationalized by an initial transnitrosation step. These results suggest that, in contrast to many other genotoxic N-nitrosocompounds which are known to alkylate DNA, the genotoxicity of N-nitrosoindoles is likely to arise through transfer of the nitroso group to nucleophilic sites on the purine bases. All of the products resulting from transnitrosation by N-nitrosoindoles are potentially mutagenic. These findings reveal a new pathway for N-nitrosocompounds to exert genotoxicity.  (+info)

Studies of structure and mechanism in acetonitrile chemical ionization tandem mass spectrometry of polyunsaturated fatty acid methyl esters. (2/350)

Recently it has been shown that acetonitrile chemical ionization tandem mass spectrometry (CI-MS/MS) is a rapid, on-line means to determine double bond position in fatty acid methyl esters (FAME). The mechanism of this gas phase condensation reaction has been studied. Evidence of the (1-methyleneimino)-1-ethenylium ion (m/z 54), formed upon the reaction of acetonitrile with itself, adding across the double bond in a [2 + 2] cycloaddition reaction is observed. When this nascent complex undergoes collision-induced dissociation, two diagnostic ions emerge. One of these ions results from loss of the hydrocarbon end of the FAME, whereas the other ion results from loss of the methyl ester end, and when considered together, the diagnostic ions localize the positions of the double bonds in the FAME. Several labeling and MS/MS/MS experiments on the two diagnostic ions were performed to determine a plausible fragmentation mechanism of the stable (1-methyleneimino)-1-ethenylium-FAME complex. The first generation product ions, or diagnostic ions, appear to be formed though a charge-driven mechanism, whereas the second generation product ions are formed via charge-remote fragmentations. Plausible mechanisms for the formation and subsequent dissociation of the diagnostic ions are presented for the monounsaturated, diunsaturated, and polyunsaturated (3 or more double bonds) FAME.  (+info)

Stimulation of tolbutamide hydroxylation by acetone and acetonitrile in human liver microsomes and in a cytochrome P-450 2C9-reconstituted system. (3/350)

Organic solvents are often used to solubilize lipophilic new chemical entities before their addition to in vitro test systems such as microsomal stability or cytochrome P-450 (CYP) inhibition. However, the effect of these organic solvents on the test systems is not usually characterized. This study was initiated to evaluate the effect of acetonitrile and acetone, in addition to other organic solvents, on the tolbutamide hydroxylation activity of CYP2C9 in both human liver microsomes and a CYP2C9-reconstituted system. Both acetonitrile and acetone significantly stimulated the NADPH-dependent tolbutamide hydroxylation by nearly 2- to 3-fold in human liver microsomes and CYP2C9-reconstituted system when incubated at 2 and 4% final solvent concentrations. When cumene hydroperoxide was used instead of NADPH, both acetone and acetonitrile significantly inhibited tolbutamide hydroxylation. This NADPH-dependent stimulatory effect was further evaluated by examining the effect of a series of other organic solvents with different carbon chain lengths and various functional groups, including hydroxyl, ketone, and aldehyde. Unlike acetone, two other ketone-containing solvents, methyl ethyl ketone (2-butanone) and diethyl ketone (3-pentanone) failed to significantly enhance tolbutamide hydroxylation. Other solvents tested, including methanol, ethanol, propanol, 1-butanol, 2-butanol, 1-pentanol, 2-pentanol, acetaldehyde, and dimethyl sulfoxide significantly inhibited NADPH-dependent tolbutamide hydroxylation. Overall, the stimulatory effect of both acetonitrile and acetone on tolbutamide hydroxylation was found to be primarily due to a consistent increase in V(max), whereas K(m) was unchanged in both human liver microsomes and the reconstituted CYP2C9 system. These data suggest that acetone and acetonitrile stimulate NADPH-mediated tolbutamide hydroxylation via the CYP reductase and not by modifying the affinity of tolbutamide for the CYP2C9 enzyme.  (+info)

Substrate-dependent effect of acetonitrile on human liver microsomal cytochrome P450 2C9 (CYP2C9) activity. (4/350)

Acetonitrile is an organic solvent commonly used to increase the solubility of lipophilic substrates for in vitro studies. In this study, we examined its effect on four reactions (diclofenac hydroxylation, tolbutamide methyl hydroxylation, phenytoin hydroxylation, and celecoxib methyl hydroxylation) catalyzed by human liver microsomes and by the recombinant CYP2C9. In both cases, the effect of acetonitrile on activity was found to be substrate-dependent. Namely, it increased diclofenac 4'-hydroxylase and tolbutamide methyl hydroxylase activities, but decreased celecoxib methyl hydroxylase activity in a concentration-dependent manner. By comparison, hydroxylation of phenytoin was resistant to its effect. The presence of acetonitrile (3%, v/v) gave rise to a lower K(m) and a higher V(max) for diclofenac hydroxylase in both liver microsomes and recombinant CYP2C9 preparations (87 and 52% increase in V(max)/K(m) ratio, respectively). On the other hand, the inhibitory effect of the solvent (1%, v/v) toward celecoxib hydroxylase was characterized by a decrease in V(max) (human liver microsomes) or a change in both K(m) and V(max) (rCYP2C9), leading to 25 and 46% decrease in V(max)/K(m) for both systems. The results of this study underscore the need for careful evaluation of solvent effects before initiation of inhibition or cytochrome P450 reaction phenotyping studies.  (+info)

High-throughput method development approaches for bioanalytical mass spectrometry. (5/350)

A rational approach to the development and optimization of solid-phase extraction (SPE) methods is described. The semiautomated scheme allows for the simultaneous testing of multiple chemistries using a custom multiple-sorbent 96-well method development plate. Optimized extraction conditions for up to five analytes are determined in a single 2.5-h experiment. The experiment can be tailored to determine SPE conditions (including wash protocols) for related analytes. Data obtained by liquid chromatography-atmospheric pressure ionization-mass spectrometry allows the quantitation of absolute recovery and selection of the best extraction conditions for approximately 100 analytes of diverse structure. Optimized extraction protocols yielding at least 80% recovery are determined for 81% of the analytes. For 96% of the analytes screened, extraction conditions resulting in recoveries of > or = 60% are determined. The most generic set of SPE conditions consist of either C8 or C18 sorbent with an eluent composition of acetonitrile with 5mM nitric acid added.  (+info)

High-performance liquid chromatographic determination of amphotericin B in a liposomal pharmaceutical product and validation of the assay. (6/350)

A validated high-performance liquid chromatographic method is presented to quantitate amphotericin B (AB) in a liposomal pharmaceutical formulation. The analysis is based on the chromatographic separation of AB and 1-amino-4-nitronaphthalene (the internal standard) on a C18 muBondapac reversed-phase column with a mobile phase consisting of a mixture of acetonitrile and 0.02 M ethylenediamine tetra-acetic acid disodium salt at pH 5.0 (45:55, v/v). The chromatographic analysis time is less than 10 min, and the validation of the assay shows that it is selective, accurate, and linear for the concentration range of 2.50 to 7.50 microg/mL with a detection limit of 0.00500 microg/mL. The within-day and between-day relative standard deviation values are 1.26% (n = 18) and 1.25% (n = 8), respectively. The method described conforms to the validation of compendial methods used for finished pharmaceutical products in general and offers a reliable, quick, and cost-effective procedure for examining the consistency or quality-control analysis of AB in liposomal products. It can also be applied for the determination of AB in other nonliposomal lipid-based drug delivery systems that are on the market.  (+info)

Simultaneous determination of sweeteners and preservatives in preserved fruits by micellar electrokinetic capillary chromatography. (7/350)

A micellar electrokinetic capillary method for the simultaneous determination of the sweeteners dulcin, aspartame, saccharin, and acesulfame-K and the preservatives sorbic acid; benzoic acid; sodium dehydroacetate; and methyl-, ethyl-, propyl-, isopropyl-, butyl-, and isobutyl-p-hydroxybenzoate in preserved fruits is developed. These additives are ion-paired and extracted using sonication followed by solid-phase extraction from the sample. Separation is achieved using a 57-cm fused-silica capillary with a buffer comprised of 0.05 M sodium deoxycholate, 0.02 M borate-phosphate buffer (pH 8.6), and 5% acetonitrile, and the wavelength for detection is 214 nm. The average recovery rate for all sweeteners and preservatives is approximately 90% with good reproducibility, and the detection limits range from 10 to 25 microg/g. Fifty preserved fruit samples are analyzed for the content of sweeteners and preservatives. The sweeteners found in 28 samples was aspartame (0.17-11.59 g/kg) or saccharin (0.09-5.64 g/kg). Benzoic acid (0.02-1.72 g/kg) and sorbic acid (0.27-1.15 g/kg) were found as preservatives in 29 samples.  (+info)

Lactobacillus arizonensis sp. nov., isolated from jojoba meal. (8/350)

Five strains of simmondsin-degrading, lactic-acid-producing bacteria were isolated from fermented jojoba meal. These isolates were facultatively anaerobic, gram-positive, non-motile, non-spore-forming, homofermentative, rod-shaped organisms. They grew singly and in short chains, produced lactic acid but no gas from glucose, and did not exhibit catalase activity. Growth occurred at 15 and 45 degrees C. All strains fermented cellobiose, D-fructose, D-galactose, D-glucose, lactose, maltose, D-mannitol, D-mannose, melibiose, D-ribose, salicin, D-sorbitol, sucrose and trehalose. Some strains fermented L-(-)-arabinose and L-rhamnose. D-Xylose was not fermented and starch was not hydrolysed. The mean G+C content of the DNA was 48 mol%. Phylogenetic analyses of 16S rDNA established that the isolates were members of the genus Lactobacillus. DNA reassociation of 45% or less was obtained between the new isolates and the reference strains of species with G+C contents of about 48 mol%. The isolates were differentiated from other homofermentative Lactobacillus spp. on the basis of 16S rDNA sequence divergence, DNA relatedness, stereoisomerism of the lactic acid produced, growth temperature and carbohydrate fermentation. The data support the conclusion that these organisms represent strains of a new species, for which the name Lactobacillus arizonensis is proposed. The type strain of L. arizonensis is NRRL B-14768T (= DSM 13273T).  (+info)

TY - JOUR. T1 - Microscopic trends in methanol/water and acetonitrile/water systems. AU - Alzweiri, Muhammed. AU - Parkinson, John. AU - Watson, David. AU - Steer, Steven. PY - 2011. Y1 - 2011. N2 - Examination of some trends and differences between acetonitrile/water and methanol/water mixtures has been carried out. These systems are of interest for chromatographers since they are common mobile constituents. Some differences in the molecular arrangement of these solvents were observed from NMR and IR results. These observations might be of use in understanding and developing chromatographic separations. IR studies revealed C-H bond compression in methanol compared with acetonitrile which indicates different molecular arrangement in their aqueous mixtures. NMR and IR results show a clear non-linear behaviour in molecular arrangement. This justifies the deviation of methanol and acetonitrile aqueous solution from the norm. However, both solvents showed similar ionization suppression effects on ...
A system includes a process-related-data handling component operative to handle process-related data corresponding to an operation associated with an artifact, such as the creation or revision of the artifact. An application component is operatively coupled to the process-related-data handling module and is operative to interact with the artifact. A storage element is also operatively coupled to the process-related-data handling module and is operative to store the process-related data. The process-related data may be displayed, created, or otherwise manipulated through a data management tool, which may include, a calendar interface, a task interface, and/or a media capture module. A method is also directed towards establishing process-related context concerning at least one artifact.
Acetonitrile (also called methyl cyanide, ethanenitrile, ethyl nitrile, etc.) is the simplest organic nitrile with the molecular formula of C2H3N. It is a clear, flammable liquid, melting and boiling at -45°C and 82°C respectively. Acetonitrile is miscible with water and with common organic solvents, but immiscible with many saturated hydrocarbons (alkanes).. Acetonitrile is produced by dehydration of acetamide or by the reaction of ethanol and ammonia in the presence of catalyst such as Ag, Cu, MoO3, and ZnS at moderate temperatures as well as a by-product from the manufacture of acrylonitrile. Acetonitrile can also obtained by the reaction of cyanogen chloride with methane, ketones, ethanol, alkylene epoxides, and paraffins.. Acetonitrile finds its greatest use as an extractive distillation solvent in the petrochemical industry for separating olefin-diolefin mixtures and for C4-hydrocarbons.. It is widely used in battery applications because of its relatively high dielectric constant and ...
The charge transfer (CT) interaction of 2-aminopyrimidine (AP) with chloranilic acid (CLA) as π-acceptor was investigated spectrophotometrically in acetonitrile at different temperatures in the range of 25-50 C. The 1:1 stoichiometry of the synthesized CT complex was detected using straight line method. Benesi-Hildebrand equation was used to determine the association constant (K ), molar extinction coefficient (ε) and other physical parameters. Various thermodynamics parameters such as enthalpy (ΔH), entropy (ΔS) and free energy (ΔG) were determined using UV-Visible spectrophotometry in acetonitrile at different temperatures. H NMR, FTIR, ESI-MS, elemental analyses, and UV-Visible techniques were used to characterize the hydrogen-bonded CT complex. H NMR spectroscopy was also used for the analysis of the CT complex where both hydrogen bond and charge transfer were present in its molecular composition. The interaction of the selected organic compound with Ct-DNA was well investigated using ...
The synthesis and physicochemical properties of 2-(5-methoxyphenyl-1H-1,2,4-triazole-3-ylthio) acetonitriles and their iminoethers
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Absorption Quantitative data are not available for absorption of acetonitrile from the gastrointestinal or respiratory tract, although sufficient absorption can occur to induce systemic toxicity as evidenced by animal and human toxicity data. The dermal absorption of acetonitrile has been studied quantitatively. In a guideline (OECD 428 equivalent) and GLP study conducted by Haskell Laboratories (2005), the in vitro absorption of acetonitrile through human cadaver skin was shown to be low. The permeability coefficient was calculated to be 1.82 x 10-4cm/h. Short-term penetration rates were calculated to be 375.6 μg equiv/cm2/h (10 minute exposure) and 66.0 μg equiv/cm2/h (60 minute exposure). The majority of an infinite dose of acetonitrile was removed from the skin surface at the end of the 8-hour exposure, and only a small portion penetrated the skin and was recovered in the receptor fluid (0.24%). Following a 10- and 60-minute exposure, a major portion of a finite dose was recovered in the ...
Two new dinuclear nickel(II) complexes namely [Ni2(L1)2(OAc)2(H2O)2].CH3CN (1) and [Ni2(L2)2(SCN)2(CH3OH)2].CH3OH (2) have been synthesized from designed Schiff-base ligand 4-Bromo-2-[(2-hydroxy-1,1-dimethyl-ethylimino)-methyl]-phenol (HL1) and its reduced analogue 4-Bromo-2-[(2-hydroxy-1,1-dimethyl-ethylamino)-methyl]-phenol (HL2), respectively. Both 1 and 2 have been characterised by usual physicochemical techniques (UV-Vis, FT-IR, ESI-MS study, Single crystal XRD) and their variable temperature magnetic study has been performed. The nickel(II) centres in the dinuclear complexes 1 and 2 are antiferromagnetically coupled through participation of bridging phenoxyl oxygen. In acetonitrile solution both 1 and 2 retain their dinuclear structural integrity as is evident from ESI-MS study. Catecholase like activity of 1 and 2 have been performed in acetonitrile medium using 3, 5 -di-tert-butylcatechol (3, 5-DTBC) as model substrate. Complex 1 shows higher catalytic activity than that of... Read more ...
Two new dinuclear nickel(II) complexes namely [Ni2(L1)2(OAc)2(H2O)2].CH3CN (1) and [Ni2(L2)2(SCN)2(CH3OH)2].CH3OH (2) have been synthesized from designed Schiff-base ligand 4-Bromo-2-[(2-hydroxy-1,1-dimethyl-ethylimino)-methyl]-phenol (HL1) and its reduced analogue 4-Bromo-2-[(2-hydroxy-1,1-dimethyl-ethylamino)-methyl]-phenol (HL2), respectively. Both 1 and 2 have been characterised by usual physicochemical techniques (UV-Vis, FT-IR, ESI-MS study, Single crystal XRD) and their variable temperature magnetic study has been performed. The nickel(II) centres in the dinuclear complexes 1 and 2 are antiferromagnetically coupled through participation of bridging phenoxyl oxygen. In acetonitrile solution both 1 and 2 retain their dinuclear structural integrity as is evident from ESI-MS study. Catecholase like activity of 1 and 2 have been performed in acetonitrile medium using 3, 5 -di-tert-butylcatechol (3, 5-DTBC) as model substrate. Complex 1 shows higher catalytic activity than that of... Read more ...
Darstellung, Struktur und Eigenschaften von P(C6H5)4SeOCl3, P(C6H5)4SeOBr3 und As(C6H5)4SeOBr3 Oxotrihalogenoselenates(IV): Preparation, Structure and Properties of P(C6H5)4SeOCl3, P(C6H5)4SeOBr3 and As(C6H5)4SeOBr3 The novel oxotribromosolenate(IV) SeOBr3~ anion was prepared from the reaction of stoichiometric quantities of SeOBi2 and bromide in acetonitrile solution, and it was isolated as the tetraphenylphosphonium and -arsonium salts in crystalline form. For the synthesis of the analogous SeOCl3 _ as P(C6H5)4SeOCl3, SeCl4 was reacted in the presence of a small quantity of H«() with P(CeH5)4Cl in acetonitrile. Complete N-ray structural analyses of P(C6H5)4SeOCi3 (space group P I, a = 10.981(3), b = 11.059(3), c = 10.358(3) A, a = 73.77(2)°, ß = 83.33(2)°, -/ = 80.51(2)°, V -1187.9(6) A 3) and of P(C6H5)4SeOBr3 (space group P 2i/c, a = 11.719(4), b = 16.088(4), c = 13.124(4) A, ß = 94.72(3)°, V = 2466(1) A 3) show dimeric centrosymmetric Se202Cl6 2-and Se202Br6 2 -anions being present ...
Research in fluorescence microscopy presents new challenges, especially with respect to the development of new metal-based fluorophores. In this work, new fac-[Re(CO)3(bpy)L]PF6 (C3) and fac-[Re(CO)3(dmb)L]PF6 (C4) complexes, where L is an ancillary ligand, E-2-((3-amino-pyridin-4-ylimino)-methyl)-4,6-di-tert-butylphenol, both exhibiting an intramolecular hydrogen bond, have been synthesized for use as preliminary probes for fluorescence microscopy. The complexes were characterized using chemical techniques such as UV-vis, 1H-NMR, TOCSY, FT-IR, cyclic voltammetry, mass spectrometry (EI-MS 752.22 M+ for C3 and 780.26 M+ for C4) and DFT calculations including spin orbit effects. The electron withdrawing nature of the ancillary ligand L in C3 and C4 explains their electrochemical behavior, which shows the oxidation of ReI at 1.84 V for C3 and at 1.88 V for C4. The UV-vis absorption and emission properties have been studied at room temperature in acetonitrile solution. The complexes show luminescent ...
A detailed computational characterization of the one-photon absorption spectrum of a 2-((E)-2-[2,2′]-bithiophenyl-5-yl-vinyl)-1-methyl-quinolinium cation in acetonitrile solution is presented. The main physico-chemical effects (solvation, vibronic progression) affecting the band position and shape are progre
Rapid quantification of process-related contaminants enables data-driven decisions to be made throughout the biotherapeutics workflow.
On Thu, 08 Mar 2012 14:54:36 +0100, Lars Erik Bolstad ,[email protected], wrote: , Sorry for the rather late response here. , We discussed this at our f2f meeting earlier this week. , , Were about to request transition to CR for the DeviceOrientation Events , spec and from a purely process-related view were concerned about , introducing a dependency to DOM4 at this point. , , In the interest of wrapping up the work were chartered to do as a , working group now and not in 9-12 months, we decided to keep the , reference to DOM2 Events. FWIW, introducing new init*Event() methods at this stage is not really acceptable, no matter what the dependency is. And not defining an event constructor as per DOM also seems questionable, but that is at least something you could fix in the future. Also, you already depend on HTML, which depends on the latest DOM, so it seems really weird to then also depend on some really crappy out of date draft. Unrelated, the IDL in ...
Sigma-Aldrich offers Aldrich-270717, Acetonitrile for your research needs. Find product specific information including CAS, MSDS, protocols and references.
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Hazardous Materials Category 4-1(Water Soluble)-II,Deleterious-P.G II,ISHL Article 57 (Labeling),CSCL Priority Assessment,UN: Class 3 - Flamm. liq.,PRTR Class 1 Designated Chemical,ISHL Article 57-2 (Deliver of Document ...
Glycosylations range among the most common posttranslational modifications with an estimated 50% of all proteins supposed to be glycosylated. These modifications are required for essential cellular processes including cell-cell recognition, protein structure and activity, e.g., of surface receptors, as well as subcellular localization of proteins. Beside the elucidation of the carbohydrate structures, the annotation of glycosylation sites is of primary interest as a basis for subsequent functional characterization. Although mass spectrometry is the method of choice for large-scale analysis of glycosylation sites, it requires initial enrichment of glycopeptides prior mass spectrometric detection in most cases. In this paper, we present a novel approach for glycopeptide enrichment by electrostatic repulsion hydrophilic interaction chromatography (ERLIC). Glycopeptides were separated from the bulk of non-modified peptides and gradually eluted from the stationary phase with potential for isoform resolution.
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Iogenic compound aeroplysinin-1 could also be a He ``counter-culture, and have entrenched associations with cannabis use and cultivation potential
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The analysts forecast the global Acetonitrile (ACN, CAS 75-05-8) Market to exhibit a CAGR of 4.69% during the period 2019-2024. The report covers the present scenario and the growth prospects of the global acetonitrile for 2019-2024. To calculate the market size, the report considers the acetonitrile sales volume and revenue.. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: regional markets, product, and application.. Geographically, the global acetonitrile market is segmented into North America, Asia Pacific, Europe, Middle East & Africa and South America. This report forecasts revenue growth at a global, regional & country level, and provides an analysis of the market trends in each of the sub-segments from 2019 to 2024. ...
3-(Dimethylamino)propionitrile, 98%, ACROS Organics™ 100mL; Glass bottle 3-(Dimethylamino)propionitrile, 98%, ACROS Organics™ Dimethylaminob to Dimethylaz...
Whole blood from the subjects will be drawn 30 minutes, 1 hour, 2 hours, 3 hours and 4 hours post clopidogrel dose. Once the blood is drawn, the metabolite will be derivatized to keep the metabolite stable in blood. Derivatization of the metabolite, involves spiking blood samples with 2-bromo-3methoxyacetophenone contained in an acetonitrile solution. Once derivatization has been done, metabolite levels will be analyzed using liquid chromatography mass spectrometry (LCMS). Once concentration levels of the active metabolite are known, the area under the curve will be calculated under trapezoid rule (linear up, log down ...
Three new compounds, (GuaH)4[W10O32](H2O)4 (1), (ThbH)3(H3O)[(W10O32](H2O)7.5 (2) and (ThbH)2[W6O19](H2O)2 (3) (GuaH = guaninium, thbH = theobrominium) were synthesized in acidified acetonitrile solutions. The polyoxotungstates in all of these compounds are surrounded by an organic matrix consisting of protonated purine bases and water molecules. The distinctive structural arrangement of the aromatic organic cations around the polyoxoanions parallel to their faces is reminiscent of nanosized boxes. The results of IR spectroscopy are consistent with previously reported results for polyoxotungstates and neat organic compounds. The polyoxoanions are reduced to tungsten(IV) oxide upon heating over 400 °C in an intramolecular redox reaction.
Precise vapor pressure data for pure acetonitrile and (LiBr + acetonitrile) are given for temps. ranging from 298.15 to 343.15 K. The molality range is from m = (0.0579 to 0.8298) mol/kg-1. The osmotic coeffs. are calcd. by taking into account the second virial coeff. of acetonitrile. The parameters of the extended Pitzer ion interaction model of Archer and the mole fraction-based thermodn. model of Clegg-Pitzer are evaluated. These models accurately reproduce the available osmotic coeffs. The parameters of the extended Pitzer ion interaction model of Archer are used to calc. the mean molal activity coeffs. ...
Acetonitrile 75-05-8 Suppliers,provide Acetonitrile 75-05-8 product and the products related with China (Mainland) Acetonitrile 75-05-8 Henan Allgreen Chemical Co.,Ltd China (Mainland)
A normal-phase Bondapak high performance liquid chromatographic (HPLC) system was compared to two different reversed-phase Bondapak C//1//8 systems for separating and quantifying aldehydes and ketones. In the normal-phase system, isocratic elution with 2-propanol (IPA) and hexane produced the best results. One reversed-phase system consisted of two C//1//8 columns in series. The other reversed-phase system consisted of a single radial compression cartridge (RCC). Both reversed-phase systems employed solvent programming with acetonitrile/water as the mobile phase. Ultraviolet (UV) detection at 340 nm was used in all of the systems.
Biomanufacturers face a conflict between low-cost generic host cell protein (HCP) assays and highly sensitive but more costly process-specific HCP assays that are usually not initiated until the proof-of-concept stage. But drug developers cannot expect sufficient sensitivity from most commercially available generic assays. For some companies, multiproduct HCP assays could offer a solution to the dilemma. Biopharmaceutical manufacture using genetically modified microorganisms and cell lines is typically associated with contamination by process-related impurities. One of the most important…. ...
Principal Investigator:OGAWA Yasutaka, Project Period (FY):1990 - 1992, Research Category:Grant-in-Aid for General Scientific Research (C), Research Field:Hygiene
Phenol, 4-fluoro-, compd. with acetonitrile (1:1) | C8H8FNO | CID 71385070 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
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The Non-Aqueous Solvent (NAS) CO2 Capture Process is being developed as an advanced, next-generation post-combustion capture technology for CO2 removal from power generation and industrial flue gas streams. The core of the NAS process has been the development of a family of CO2-selective NASs that have the potential to substantially reduce the thermal regeneration energy demand associated with solvent regeneration to ? 2,000 kJt/kg of CO2 captured.
1-Naphthyl acetonitrile 132-75-2 NMR spectrum, 1-Naphthyl acetonitrile H-NMR spectral analysis, 1-Naphthyl acetonitrile C-NMR spectral analysis ect.
After cleaning, the membranes are split longitudinally into strips of varying width, which, when assembled cheap small numbers, according to the diameter required, are twisted under tension, dried, polished, selected and sterilised. Buy Benserazide hydrochloride ппMobile phase в mobilephaseA10gLsolutionoftetrabutylammonium hydrogen Buy cheap Silagra uk R; в mobile Time (min) 0 - 15 15 - 20 20 - 25 phase B acetonitrile Mobile phase Buy cheap Silagra uk (per cent Silaga 100 в 60 60 100 R ; ппMobile phase B (per cent VV) 0 в 40 40 0 C.
... technology is used by 95% of the worlds acrylonitrile and is the worlds largest manufacture of acetonitrile, with four global sites.
Číslo patentu: E 13665. Dátum: 15.04.2010. Autori: Gelmi Maria Luisa, Fontana Gabriele, Gassa Federico. MPK: C07C 227/32. Značky: derivátov, izoserínových, spôsob, přípravy. Text:. ...diastereoizoméry po jednoduchom kryštalizačnom kroku.0019 Podla tohto spôsobu imín 4 sa najskôr generuje in situ z aldehydu (RCHO) a amínu(RzNHg, kde PhCHZNHZ je výhodný) v acetonitrile pri teplote miestnosti a v prítomnosti molekulámych sít alebo pomocou destilácie azeotropickej zmesi acetonitril/voda. Reakčná teplota je znížená na -30 °C a pridáva sa silylový derivát 3. Potom sa pridáva katalyzátor a zmes sa mieša v priebehu 1 hodiny. Surová.... ...
2.5L Acetonitrile - BioSolv - (10 ppm H20), GL45 Finish *** REAGENTS CANNOT BE ORDER THROUGH SHOPIFY. PLEASE CONTACT [email protected] TO PLACE ORDER. ***
A cobalt-rhodium heterobimetallic nanoparticle-catalyzed reductive cyclization of 2-(2-nitroaryl)acetonitriles to indoles proceeds without any additives under mild conditions. The catalytic can be reused more than ten times without loss of catalytic activity.. ...
The Antiangiogenic Compound Aeroplysinin-1 Induces Apoptosis in Endothelial Cells by Activating the Mitochondrial Pathway. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
The effects of some factors important in ion-pair, high-performance liquid chromatography were studied in ion-pair, thin-layer chromatography. Tetramethyl and cetyltrimethylammonium salts were used...
0184]Nitriles compounds listed in the CRC Handbook (pages 344-368) can be used in this invention include but not limited to the followings: Cyanoacetylene, Cyanoacetaldehyde, Acrylonitrile, Fluoroacetonitrile, Acetonitrile (or Cyanomethane), Trichloroacetonitrile, Methacrylonitrile (or α-Methylacrylonitrile), Proionitrile (or Cyanoethane), Isobutyronitrile, Trimethylacetonitrile (or tert-Butylcyanide), 2-Ethyacrylonitrile, Dichloroacetonitrile, α Chloroisobutyronitrile, n-Butyronitrile (or 1-Cyanopropane), trans-Crotononitrile, Allycyanide, Methoxyacetonitrile, 2 Hydroxyisobutyronitrile (or Acetone cyanohydrins), 3-Hydroxy-4-methoxybenzonitrile, 2-Methylbutyronitrile, Chloroacetonitrile, Isovaleronitrile, 2,4-Pentadienonitrile, 2-Chlorocrotononitrile, Ethoxyacetonitrile, 2-Methycrotononitrile, 2-Bromoisobutyronitrile, 4-Pentenonitrile, Thiophene-2,3-dicarbonitrile (or 2,3-Dicyanothiophene), 3,3-Dimethylacrylonitrile, Valeronitrile (or 1 Cyanobutane), 2-Chlorobutyronitrile, Diethylacetonitrile, ...
A method for the purification of crude acetonitrile comprising distilling the crude acetonitrile in a first fractional distillation column at below atmospheric pressure, withdrawing a first side draw fraction comprising acetonitrile, distilling the first side draw fraction in a second fractional distillation column at super atmospheric pressure, and withdrawing from the second distillation a second side draw fraction comprising purified acetonitrile.
As part of a comprehensive program to discover α9α10 nicotinic acetylcholine receptor antagonists, the title compounds C30H36N2, (I), and C36H48N2, (II), were synthesized by coupling 4,4′-bis(3-bromoprop-1-yn-1-yl)-1,1′-biphenyl with 4-methylpiperidine and 2,2,6,6-tetramethylpiperidine, respectively, in acetonitrile at room temperature. In compound (I), the biphenyl system has a twisted conformation with a dihedral angle of 26.57 (6)° between the two phenyl rings of the biphenyl moiety, while in compound (II), the biphenyl moiety sits on a crystallographic inversion centre so the two phenyl rings are exactly coplanar. The terminal piperidine rings in both compound (I) and compound (II) are in the chair conformation. In compound (I), the dihedral angles about the ethynyl groups between the planes of the phenyl rings and the piperidine ring N atoms are 37.16 (16) and 14.20 (17)°. In compound (II), the corresponding dihedral angles are both 61.48 (17)°. There are no noteworthy ...
Dear Sir, I want to separate L-Alanyl-L-glutamine Impurities in I.V. injection of same on HPLC. I have done the same using Trifluroacetic acid as mobile phase on C-18 column, but Impurities can not separated by various composition of same mobile phase. It will be highly useful to me if your focus sume information in this regards. E-mail address: shaileshgajjar at rediffmail.com Thanks with best regards, Shailesh Gajjar Group Leader-Analytical Claris lifesciences limited, 6 th floor, sangeetya, Nr. Parimal crossing, Ellisbridge, Ahmedabad-380 006 Gujarat INDIA -------------- next part -------------- An HTML attachment was scrubbed... URL: http://iubio.bio.indiana.edu/bionet/mm/methods/attachments/20010129/8ca6cddd/attachment.html ...
Fractions of dissolved organic matter (DOM) from the Loire and the Gartempe rivers were obtained using Amberlite XAD resin fractionation procedure. According to the eluting system used and to the polarity of their components, the fractions were termed hydrophobic (HPO) and transphilic (TPI) for the Loire (elution with acetonitrile/water mixture) and hydrophobic acid (HPOA) and transphilic acid (TPIA) for the Gartempe (elution with NaOH). In addition, for the Loire, colloids (COL) were pre-isolated through a dialysis step. The composition of the three fractions from the Loire was investigated with solid state cross polarisation/magic angle spinning (CP/MAS) 13C NMR and Curie point pyrolysis at 650°C with and without tetramethylammonium hydroxide (TMAH). Separation and identification of the released compounds were performed using gas-chromatography/mass spectrometry (GC/MS) and focussed on nitrogen-containing pyrolysis products (N-products). Quantitative differences were observed between the ...
In the static coating procedure the entire column is filled with the coating solution and after filling one end of the column is sealed.. ...
acetonitrile. 0.004. methanol. 0.00004. water. 1.3 × 10−11. pentane. 0.004. octane. 0.025. ...
acetonitrile. 37.5. 293 water. 78.4. 298 formamide. 109. 293 Measurement[edit]. The relative static permittivity, εr, can be ...
Acetonitrile. 0.024 Acetone. 0.00091 Formamide. 62 Acetamide. 24.5 Dimethylformamide. 0.17-0.5 Solutions of KCl are common ...
From left to right: 1. water, 2. methanol, 3. ethanol, 4. acetonitrile, 5. dimethylformamide, 6. acetone, 7. ethyl acetate, 8. ...
Acetonitrile, hydrogen cyanide and acrolein are known by-products. It is used in the preparation of homo- and copolymers, ... acetonitrile. There are two types of polymers that can be obtained at the end of the synthesis; a physisorbed polymer and a ...
The dye dissolves very well in water as well as other polar solvents, e.g., Dimethylformamide, acetonitrile. Texas Red, ...
For example, of the ligands acetonitrile, chloride ion and pyridine thepriority number assigned are chloride, 1; acetonitrile,2 ... If there are two possibilities the principle of trans difference is applied). As an example, (acetonitrile)dichlorido(pyridine) ... The ligand priority numbers are, applying the CIP rules: two chlorides of priority number 1 acetonitrile priority 2 pyridine ... acetonitrile)dichlorido(pyridine)platinum(II). The configuration index has two digits. The first digit is the priority number ...
Acetonitrile‎; 18:42 . . (+4)‎ . . ‎. Smokefoot. (talk , contribs)‎ (→‎Ligand in coordination chemistry: Bis(acetonitrile) ...
Acetonitrile (MeCN). CH3-C≡N. 82 °C. 37. 0.786 g/ml. ...
I. Metal ions which have comparable polarographic properties in acetonitrile and in water." J. Am. Chem. Soc. 79 870-874. R. L ... I. M. Kolthoff and J. F. Coetzee (1957). "Polarography in acetonitrile. ...
Acetonitrile. 0.003 Acetone. 0.00042 The attraction between the Na+ and Cl− ions in the solid is so strong that only highly ...
Some pKa values at 25 °C for acetonitrile (ACN)[33][34][35] and dimethyl sulfoxide (DMSO)[36] are shown in the following tables ... pKa values of organic compounds are often obtained using the aprotic solvents dimethyl sulfoxide (DMSO)[31] and acetonitrile ( ... Acidity-Basicity Data in Nonaqueous Solvents Extensive bibliography of pKa values in DMSO, acetonitrile, THF, heptane, 1,2- ... Acetonitrile is less basic than DMSO, and, so, in general, acids are weaker and bases are stronger in this solvent. ...
Acetonitrile N 60 Et2O O 78.8 THF O 90.4 acetone O 76.0 ...
"Acetonitrile (EHC 154, 1993)". www.inchem.org. Retrieved 2017-05-03. Akagah B, Lormier AT, Fournet A, Figadère B (December 2008 ... For example, phase I metabolism converts acetonitrile to HOCH2CN, which rapidly dissociates into formaldehyde and hydrogen ...
Acetonitrile (acetonitrilo). CH3CN. neutral. monodentate. Pyridine (py). C5H5N. neutral. monodentate. ...
"The oxidising and fluoride ion acceptor properties of uranium hexafluoride in acetonitrile". J. Chem. Soc., Dalton Trans. (3): ... fluoride with uranium hexafluoride in acetonitrile is reported to form copper(II) heptafluorouranate(VI), Cu(UF7)2.[9] ...
Bühl, Michael; Sieffert, Nicolas; Chaumont, Alain; Wipff, Georges (2011-01-03). "Water versus Acetonitrile Coordination to ...
"Basicity of Phosphanes and Diphosphanes in Acetonitrile". European Journal of Organic Chemistry. 2012 (11): 2167-2172. doi: ...
Titration of NBu+ 4BF− 4 in acetonitrile solution indicates that HBF4, i.e., HF.BF3, has a pKa of 1.6 in that solvent. Its ... Acetonitrile solutions cleave acetals and some ethers. Many reactive cations have been obtained using fluoroboric acid, e.g. ... Heintz, R. A.; Smith, J. A.; Szalay, P. S.; Weisgerber, A.; Dunbar, K. R. (2002). "Homoleptic Transition Metal Acetonitrile ...
... sparingly soluble in isopropyl alcohol and acetonitrile; slightly soluble in diethyl ether; and very slightly soluble in ...
An adduct is also formed with acetonitrile. When mixed with petrol or l-hexene, or other unsaturated hydrocarbons, vanadyl ... Vanadium metal reacts with dinitrogen tetroxide with an acetonitrile catalyst at 0 °C to yield mononitratodioxovanadium(V), ...
Tetrakis(acetonitrile)copper(I) hexafluorophosphate ([Cu(MeCN)4]PF6), a colorless solid that serves as a source of naked "Cu+" ... "Acetonitrile Complexes of Selected Transition Metal Cations". Inorg. Synth. 28: 63-67. doi:10.1002/9780470132593.ch14. CS1 ... Homoleptic Transition Metal Acetonitrile Cations with Tetrafluoroborate or Trifluoromethanesulfonate Anions". Inorg. Synth. 33 ... Typical nitrile ligands are acetonitrile, propionitrile, and benzonitrile. These ligands are also popular solvents, which is ...
Kaupmees, K.; Kaljurand, I.; Leito, I. (2014). "Influence of Water Content on Basicities in Acetonitrile". J. Sol. Chem. 43: ... "Influence of Water Content on the Acidities in Acetonitrile. Quantifying Charge Delocalization in Anions". J. Phys. Chem. A. ...
Solvents include trifluoroacetic acid, methanol, dichloromethane, chloroform and acetonitrile. Many derivatives of ...
Coupling of Carbon Dioxide and Acetonitrile," J. Am. Chem. Soc., 100, 7577 (1978). C. A. Tolman, S. D. Ittel, A. D. English, ...
... acetonitrile (CHEBI:38472). acetonitrile oxide (CHEBI:47841) has functional parent acetonitrile (CHEBI:38472). acetonitrile ... 2-methylphenyl)acetonitrile (CHEBI:27982) has functional parent acetonitrile (CHEBI:38472). (hydroxyimino)(phenyl)acetonitrile ... acetonitrile (CHEBI:38472) has role EC 3.5.1.4 (amidase) inhibitor (CHEBI:77941) acetonitrile (CHEBI:38472) has role polar ... acetonitrile (CHEBI:38472) is a aliphatic nitrile (CHEBI:80291) acetonitrile (CHEBI:38472) is a volatile organic compound ( ...
Vapor Pressures of Acetonitrile Determined by Comparative Ebulliometry, Michael B. Ewing* and Jesus C. Sanchez Ochoa, Journal ... This page provides supplementary chemical data on acetonitrile. The handling of this chemical may incur notable safety ...
Acetonitriles synonyms, Acetonitriles pronunciation, Acetonitriles translation, English dictionary definition of Acetonitriles ... acetonitrile. (redirected from Acetonitriles). Also found in: Medical, Encyclopedia. acetonitrile. (əˌsiːtəʊˈnaɪtrɪl) n. a ... Acetonitriles - definition of Acetonitriles by The Free Dictionary https://www.thefreedictionary.com/Acetonitriles ...
... has functional parent acetonitrile (CHEBI:38472) indole-3-acetonitrile (CHEBI:17566) has ... indole-3-acetonitrile (CHEBI:17566) is a indoles (CHEBI:24828) indole-3-acetonitrile (CHEBI:17566) is a nitrile (CHEBI:18379) ... indole-3-acetonitrile (CHEBI:17566) has role plant hormone (CHEBI:37848) indole-3-acetonitrile (CHEBI:17566) has role plant ... CHEBI:17566 - indole-3-acetonitrile. Main. ChEBI Ontology. Automatic Xrefs. Reactions. Pathways. Models. ...
CH3CN is acetonitrile (from acetic acid), whereas C6H5CN is benzonitrile (from benzoic acid). ... Other articles where Acetonitrile is discussed: carboxylic acid: Nomenclature: Thus, ... Thus, CH3CN is acetonitrile (from acetic acid), whereas C6H5CN is benzonitrile (from benzoic acid). ...
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
Franklin, J.L.; Wada, Y.; Natalis, P.; Hierl, P.M., Ion-molecule reactions in acetonitrile and propionitrile, J. Phys. Chem., ... Williams, T.I.; Denault, J.W.; Cooks, R.G., Proton Affinity of Deuterated Acetonitrile Estimated by the Kinetic Method with ... Hydrogen cyanide and acetonitrile, J. Chem. Phys., 1968, 48, 4765. [all data] ... High-resolution HeI photoelectron spectrum of acetonitrile, Chem. Phys. Lett., 1992, 193, 41. [all data] ...
Tris(acetonitrile)cyclopentadienylruthenium hexafluorophosphate is an organoruthenium compound with the formula [(C5H5)Ru(NCCH3 ... The Synthesis and Reactions of a Synthetically Useful Intermediate: the Cyclopentadienyltris (acetonitrile) ruthenium (II) ... which is replaced by three equivalents of acetonitrile (MeCN): [Cp(C6H6)Ru]PF6 + 3 MeCN → [CpRu(NCMe)3]PF6 + C6H6 Gill, Thomas ...
View information & documentation regarding Acetonitrile, including CAS, MSDS & more. ... Sigma-Aldrich offers a number of Acetonitrile products. ... Acetonitrile, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.5 ... Acetonitrile, Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS, ... Acetonitrile, HPLC, Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs, ...
acetonitrile synonyms, acetonitrile pronunciation, acetonitrile translation, English dictionary definition of acetonitrile. n a ... acetonitrile. Also found in: Medical, Acronyms, Encyclopedia, Wikipedia. acetonitrile. (əˌsiːtəʊˈnaɪtrɪl) n. a colourless ... Acetonitrile - definition of acetonitrile by The Free Dictionary https://www.thefreedictionary.com/acetonitrile ... 30ml of acetonitrile and 10g of sodium sulfate was added in 25g of samples and homogenized in blender for 10 min.. Residue ...
This chapter provides the diffusion coefficient of ferrocene in acetonitrile at infinite dilution for various temperature and ... Winkelmann J. (2018) Diffusion coefficient of ferrocene in acetonitrile at infinite dilution. In: Lechner M.D. (eds) Diffusion ... This chapter provides the diffusion coefficient of ferrocene in acetonitrile at infinite dilution for various temperature and ...
Acetonitrile for your research needs. Find product specific information including CAS, MSDS, protocols and references. ...
In a Guideline GLP study (CEMR, 2010) the effect of acetonitrile on the unicellular marine algae (Phaeodactylum tricornutum)was ... In a guideline (OECD 204) and GLP study, MCSI of Japan (1996) reported the 21 -day NOEC for acetonitrile in fish (Oryzias ... Reported toxicity values for acetonitrile in freshwater algae range from 520 mg/L (8-day TT in the blue-green algae Mictocystis ... The acute toxicity of acetonitrile to fish has been studied in several freshwater species. Reported LC50 values range from 730 ...
Treatment of rats with acetone along with acetonitrile potentiated acetonitrile toxicity (Pozzani et al., 1959; Smyth et al., ... Mueller et al (1996) reported the case of intentional ingestion of acetonitrile by a 39 year old woman. Harmful levels of blood ... The half-life of elimination of 14C-acetonitrile from blood and most tissues ranged from 5.52 hr in the liver to 8.45 hr in the ... Acetonitrile is slowly absorbed from the stomach and eliminated through the lungs. In the first 24 hours following oral ...
Acetonitrile. CASRN 75-05-8. *Toxicological Review (PDF) (35 pp, 144 K) ...
Acetonitrile (ACGIH:OSHA). Cyanomethane. Cyanure de methyl (French). Ethanenitrile. Ethyl nitrile. Methane, cyano- ... NIOSH Analytical Method, 1994: Acetonitrile, 1606. NTP Carcinogenesis studies (inhalation);equivocal evidence:rat NTPTR* NTP-TR ... National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ACETONITRILE-air. 10H time-weighted ...
... withdrawing a first side draw fraction comprising acetonitrile, distilling the first side draw fraction in a second fractional ... and withdrawing from the second distillation a second side draw fraction comprising purified acetonitrile. ... A method for the purification of crude acetonitrile comprising distilling the crude acetonitrile in a first fractional ... Acetonitrile feed, either crude acetonitrile, recycle acetonitrile or a combination thereof is fed via inlet line 9 and water ...
This chapter provides the diffusion coefficient of acetonitrile in dichloro-deuterio-methane at infinite dilution for various ... This chapter provides the diffusion coefficient of acetonitrile in dichloro-deuterio-methane at infinite dilution for various ... Winkelmann J. (2018) Diffusion coefficient of acetonitrile in dichloro-deuterio-methane at infinite dilution. In: Lechner M.D ...
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Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
3-methoxyphenyl acetonitrile, 2-3-methoxyphenyl acetonitrile, 3-methoxyphenylacetonitrile, 3-methoxybenzyl cyanide, m- ... 3-methoxyphenyl acetonitrile, 2-3-methoxyphenyl acetonitrile, 3-methoxyphenylacetonitrile, 3-methoxybenzyl cyanide, m- ... methoxyphenyl acetonitrile, 3-cyanomethyl anisole, benzeneacetonitrile, 3-methoxy, 3-methoxybenzeneacetonitrile, m- ... methoxyphenyl acetonitrile, 3-cyanomethyl anisole, benzeneacetonitrile, 3-methoxy, 3-methoxybenzeneacetonitrile, m- ...
Find quality suppliers and manufacturers of Acetonitrilefor price inquiry.where to buy Acetonitrile.Also offer free database of ... Acetonitrile including MSDS sheet(poisoning, toxicity, hazards and safety),chemical properties,Formula, density and structure, ... Uses of Acetonitrile: Acetonitrile is used mainly as a solvent in the purification of butadiene in refineries. It is widely ... The Acetonitrile, with the register number 75-05-8, is a kind of colorless transparent liquid. Acetonitrile is the chemical ...
Acetonitrile, Acetonitrile, ACETONITRILE, Acetonitrile, Acetonitrile, 5-Amino-4-cyano-1-phenyl-3-pyrazole acetonitrile, 2-(4.. ... Related Categories: Acetonitrile Hplc Honeywell , Acetonitrile Hplc Grade , Acetonitrile Hplc , Jt Baker Acetonitrile , ... Acetonitrile is used mainly as a solvent in the purification of butadiene in refineries. Acetonitrile plays a significant role ... pharmaceutical secondary standard; traceable to USP Synonym(s): Acetonitrile; ACN; Methyl cyanide Empirical Formula: C2H3N ...
Formal reductive addition of acetonitrile to aldehydes and ketones K. Muratov, E. Kuchuk, S. Vellalath, O. I. Afanasyev, A. P. ...
  • In a Guideline GLP study (CEMR, 2010) the effect of acetonitrile on the unicellular marine algae ( Phaeodactylum tricornutum) was assessed over 72 hours using a static, sealed test system with no head space to avoid loss of the test substance by volatilisation from the test system. (europa.eu)
  • The onset potential for ORR is shifted to less positive values in acidic media because of a blocking effect of acetonitrile. (ua.es)
  • A simple, rapid and sensitive chiral capillary zone electrophoresis coupled with acetonitrile-field-amplified sample stacking method was developed that allows the simultaneous enantioselective separation of the mirtazapine, N-demethylmirtazapine, 8-hydroxymirtazapine and mirtazapine-N-oxide. (mdpi.com)
  • After one step clean-up liquid-liquid extraction using 96-well format, sample was introduced capillary zone electrophoresis with acetonitrile-field-amplified sample stacking to enhance the sensitivity of enantiomers. (mdpi.com)
  • Abstract The pKa values of seven novel guanidine derivatives, six of them possessing heteroalkyl substituents capable of forming intramolecular hydrogen bonds, were determined in acetonitrile (MeCN) by using the UV/Vis spectrophotometric titration method. (academicconcepts.net)
  • Leading Manufacturers and Exporter Offering wide range of Acetonitrile, 5- chloro salicysic acid, o-dianisidine di-hcl, fast blue b base, k.f. karlfisher, 5-amino salicylic acid, 5-nitro salicylic acid, acetonitrile, fine chemicals. (exportersindia.net)
  • Sciencemadness Discussion Board » Non-chemistry » Legal and Societal Issues » Why is acetonitrile considered a hazardous material? (sciencemadness.org)
  • W. A. A. Ddamba, Thabo T. Mokoena, Phatsimo Mokgweetsi, M. S. Nadiye-Tabbiruka, Modeling of Excess Molar Volumes of [Difurylmethane + (Acetonitrile or Propionitrile or Benzonitrile)] Binary Mixtures Using the Prigogine - Flory - Patterson Theory, American Journal of Physical Chemistry . (sciencepublishinggroup.com)
  • Free and conjugated hydrogen cyanide has been detected in a wide range of tissues following administration of acetonitrile (Haguenoer et al, 1975). (europa.eu)
  • In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani et al. (lookchem.com)