Acetone
2-Propanol
Solvents
Butanones
Xanthobacter
1-Propanol
Plant Extracts
Ketones
Carboxy-Lyases
Methanol
Fixatives
Antisense RNA strategies for metabolic engineering of Clostridium acetobutylicum. (1/704)
We examined the effectiveness of antisense RNA (as RNA) strategies for metabolic engineering of Clostridium acetobutylicum. Strain ATCC 824(pRD4) was developed to produce a 102-nucleotide asRNA with 87% complementarity to the butyrate kinase (BK) gene. Strain ATCC 824(pRD4) exhibited 85 to 90% lower BK and acetate kinase specific activities than the control strain. Strain ATCC 824(pRD4) also exhibited 45 to 50% lower phosphotransbutyrylase (PTB) and phosphotransacetylase specific activities than the control strain. This strain exhibited earlier induction of solventogenesis, which resulted in 50 and 35% higher final concentrations of acetone and butanol, respectively, than the concentrations in the control. Strain ATCC 824(pRD1) was developed to putatively produce a 698-nucleotide asRNA with 96% complementarity to the PTB gene. Strain ATCC 824(pRD1) exhibited 70 and 80% lower PTB and BK activities, respectively, than the control exhibited. It also exhibited 300% higher levels of a lactate dehydrogenase activity than the control exhibited. The growth yields of ATCC 824(pRD1) were 28% less than the growth yields of the control. While the levels of acids were not affected in ATCC 824(pRD1) fermentations, the acetone and butanol concentrations were 96 and 75% lower, respectively, than the concentrations in the control fermentations. The lower level of solvent production by ATCC 824(pRD1) was compensated for by approximately 100-fold higher levels of lactate production. The lack of any significant impact on butyrate formation fluxes by the lower PTB and BK levels suggests that butyrate formation fluxes are not controlled by the levels of the butyrate formation enzymes. (+info)Immunofluorescence detection of ezrin/radixin/moesin (ERM) proteins with their carboxyl-terminal threonine phosphorylated in cultured cells and tissues. (2/704)
Ezrin/radixin/moesin (ERM) proteins are thought to play an important role in organizing cortical actin-based cytoskeletons through cross-linkage of actin filaments with integral membrane proteins. Recent in vitro biochemical studies have revealed that ERM proteins phosphorylated on their COOH-terminal threonine residue (CPERMs) are active in their cross-linking activity, but this has not yet been evaluated in vivo. To immunofluorescently visualize CPERMs in cultured cells as well as tissues using a mAb specific for CPERMs, we developed a new fixation protocol using trichloroacetic acid (TCA) as a fixative. Immunoblotting analyses in combination with immunofluorescence microscopy showed that TCA effectively inactivated soluble phosphatases, which maintained the phosphorylation level of CPERMs during sample processing for immunofluorescence staining. Immunofluorescence microscopy with TCA-fixed samples revealed that CPERMs were exclusively associated with plasma membranes in a variety of cells and tissues, whereas total ERM proteins were distributed in both the cytoplasm and plasma membranes. Furthermore, the amounts of CPERMs were shown to be regulated in a cell and tissue type-dependent manner. These findings favored the notion that phosphorylation of the COOH-terminal threonine plays a key role in the regulation of the cross-linking activity of ERM proteins in vivo. (+info)Dibromopropanone cross-linking of the phosphopantetheine and active-site cysteine thiols of the animal fatty acid synthase can occur both inter- and intrasubunit. Reevaluation of the side-by-side, antiparallel subunit model. (3/704)
The objective of this study was to test a new model for the homodimeric animal FAS which implies that the condensation reaction can be catalyzed by the amino-terminal beta-ketoacyl synthase domain in cooperation with the penultimate carboxyl-terminal acyl carrier protein domain of either subunit. Treatment of animal fatty acid synthase dimers with dibromopropanone generates three new molecular species with decreased electrophoretic mobilities; none of these species are formed by fatty acid synthase mutant dimers lacking either the active-site cysteine of the beta-ketoacyl synthase domain (C161A) or the phosphopantetheine thiol of the acyl carrier protein domain (S2151A). A double affinity-labeling strategy was used to isolate dimers that carried one or both mutations on one or both subunits; the heterodimers were treated with dibromopropanone and analyzed by a combination of sodium dodecyl sulfate/polyacrylamide gel electrophoresis, Western blotting, gel filtration, and matrix-assisted laser desorption mass spectrometry. Thus the two slowest moving of these species, which accounted for 45 and 15% of the total, were identified as doubly and singly cross-linked dimers, respectively, whereas the fastest moving species, which accounted for 35% of the total, was identified as originating from internally cross-linked subunits. These results show that the two polypeptides of the fatty acid synthase are oriented such that head-to-tail contacts are formed both between and within subunits, and provide the first structural evidence in support of the new model. (+info)Evidence for an inducible nucleotide-dependent acetone carboxylase in Rhodococcus rhodochrous B276. (4/704)
The metabolism of acetone was investigated in the actinomycete Rhodococcus rhodochrous (formerly Nocardia corallina) B276. Suspensions of acetone- and isopropanol-grown R. rhodochrous readily metabolized acetone. In contrast, R. rhodochrous cells cultured with glucose as the carbon source lacked the ability to metabolize acetone at the onset of the assay but gained the ability to do so in a time-dependent fashion. Chloramphenicol and rifampin prevented the time-dependent increase in this activity. Acetone metabolism by R. rhodochrous was CO2 dependent, and 14CO2 fixation occurred concomitant with this process. A nucleotide-dependent acetone carboxylase was partially purified from cell extracts of acetone-grown R. rhodochrous by DEAE-Sepharose chromatography. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis suggested that the acetone carboxylase was composed of three subunits with apparent molecular masses of 85, 74, and 16 kDa. Acetone metabolism by the partially purified enzyme was dependent on the presence of a divalent metal and a nucleoside triphosphate. GTP and ITP supported the highest rates of acetone carboxylation, while CTP, UTP, and XTP supported carboxylation at 10 to 50% of these rates. ATP did not support acetone carboxylation. Acetoacetate was determined to be the stoichiometric product of acetone carboxylation. The longer-chain ketones butanone, 2-pentanone, 3-pentanone, and 2-hexanone were substrates. This work has identified an acetone carboxylase with a novel nucleotide usage and broader substrate specificity compared to other such enzymes studied to date. These results strengthen the proposal that carboxylation is a common strategy used for acetone catabolism in aerobic acetone-oxidizing bacteria. (+info)Urinary volatile constituents of the lion, Panthera leo. (5/704)
The volatile components of urine from lions were investigated using GC-MS headspace techniques. Fifty-five compounds were found in the urine samples. Seven potential species-identifying compounds were found. Male lion scent marks overlapped significantly more in compound composition with other males than they did with female marks. A similar relationship was not found for the females. Males had a significantly higher absolute content of 2-butanone in their urine than females, and females had a significantly higher relative content of acetone than males. Samples from 13/16 individual lions overlapped more within the individual than they did with samples from the other individuals, but only seven significantly so. (+info)Toxicokinetic interactions between orally ingested chlorzoxazone and inhaled acetone or toluene in male volunteers. (6/704)
The aim of this study was to examine if the drug chlorzoxazone has any influence on the toxicokinetics of acetone and toluene. Chlorzoxazone is mainly metabolized by the same enzyme (Cytochrome P450 2E1) as ethanol and many other organic solvents. Ten male volunteers were exposed to solvent vapor (2 h, 50 watt) in an exposure chamber. Each subject was exposed to acetone only (250 ppm), acetone + chlorzoxazone, toluene (50 ppm) only, toluene + chlorzoxazone, and chlorzoxazone only. Chlorzoxazone (500 mg) was taken as two tablets 1 h prior to solvent exposure. Samples of blood, urine and exhaled air were collected before, during and until 20 h post exposure. The samples were analyzed by head-space gas chromatography (acetone and toluene) and high-performance liquid chromatography (chlorzoxazone, 6-hydroxychlorzoxazone and hippuric acid). The time-concentration curves of acetone and toluene in blood were fitted to one- and four-compartment toxicokinetic models, respectively. Intake of chlorzoxazone was associated with slight but significant increases in the area under the blood concentration-time curve (AUC) and steady state concentration of acetone in blood, along with non significant tendencies to an increased half time in blood and an increased AUC in urine. Except for a delayed excretion of hippuric acid in urine, no effects on the toluene toxicokinetics were seen after chlorzoxazone treatment. Small increases in chlorzoxazone plasma levels were seen after exposure compared to chlorzoxazone alone. These interactions, although statistically significant, seem to be small compared to the interindividual variability on metabolism and toxicokinetics. (+info)Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. (7/704)
Procyanidins present in grape seeds are known to exert anti-inflammatory, anti-arthritic and anti-allergic activities, prevent skin aging, scavenge oxygen free radicals and inhibit UV radiation-induced peroxidation activity. Since most of these events are associated with the tumor promotion stage of carcinogenesis, these studies suggest that grape seed polyphenols and the procyanidins present therein could be anticarcinogenic and/or anti-tumor-promoting agents. Therefore, we assessed the anti-tumor-promoting effect of a polyphenolic fraction isolated from grape seeds (GSP) employing the 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol 13-acetate (TPA)-promoted SENCAR mouse skin two-stage carcinogenesis protocol as a model system. Following tumor initiation with DMBA, topical application of GSP at doses of 0.5 and 1.5 mg/mouse/application to the dorsal initiated mouse skin resulted in a highly significant inhibition of TPA tumor promotion. The observed anti-tumor-promoting effects of GSP were dose dependent and were evident in terms of a reduction in tumor incidence (35 and 60% inhibition), tumor multiplicity (61 and 83% inhibition) and tumor volume (67 and 87% inhibition) at both 0.5 and 1.5 mg GSP, respectively. Based on these results, we directed our efforts to separate and identify the individual polyphenols present in GSP and assess their antioxidant activity in terms of inhibition of epidermal lipid peroxidation. Employing HPLC followed by comparison with authentic standards for retention times in HPLC profiles, physiochemical properties and spectral analysis, nine individual polyphenols were identified as catechin, epicatechin, procyanidins B1-B5 and C1 and procyanidin B5-3'-gallate. Five of these individual polyphenols with evident structural differences, namely catechin, procyanidin B2, procyanidin B5, procyanidin C1 and procyanidin B5-3'-gallate, were assessed for antioxidant activity. All of them significantly inhibited epidermal lipid peroxidation, albeit to different levels. A structure-activity relationship study showed that with an increase in the degree of polymerization in polyphenol structure, the inhibitory potential towards lipid peroxidation increased. In addition, the position of linkage between inter-flavan units also influences lipid peroxidation activity; procyanidin isomers with a 4-6 linkage showed stronger inhibitory activity than isomers with a 4-8 linkage. A sharp increase in the inhibition of epidermal lipid peroxidation was also evident when a gallate group was linked at the 3'-hydroxy position of a procyanidin dimer. Procyanidin B5-3'-gallate showed the most potent antioxidant activity with an IC(50) of 20 microM in an epidermal lipid peroxidation assay. Taken together, for the first time these results show that grape seed polyphenols possess high anti-tumor-promoting activity due to the strong antioxidant effect of procyanidins present therein. In summary, grape seed polyphenols in general, and procyanidin B5-3'-gallate in particular, should be studied in more detail to be developed as cancer chemopreventive and/or anticarcinogenic agents. (+info)Thapsigargin has similar effect on p53 protein response to benzo[a]pyrene-DNA adducts as TPA in mouse skin. (8/704)
The level of p53 tumor suppressor protein increases in response to DNA damage caused by benzo[a]pyrene (B[a]P). The most used tumor promoter in the two step mouse skin carcinogenesis model, 12-O-tetradecanoylphorbol-13-acetate (TPA) decreases this response in mouse skin. In this study the effect of another promoter, thapsigargin was tested on B[a]P-induced p53 response using immunohistochemistry, western blotting and immunoelectron microscopy. We also studied the localization of p53 protein after treatments with BP and TPA or thapsigargin. Thapsigargin had a TPA-like effect on the acute induction of p53 protein related to benzo[a]pyrene-7, 8-diol-9,10-epoxide-DNA adducts in the skin of C57BL/6 mouse. After B[a]P treatment, there was slightly more putatively wild-type p53 protein in nuclei than in cytoplasm of the cells. Neither TPA nor thapsigargin affected the localization of p53 protein. Since both compounds increase the level of intracellular calcium, the inhibition of the p53 response may depend on the level of intracellular calcium. Inhibition of the putatively genome-protecting increase in p53 protein may be one of the critical effects of tumor promoters. (+info)Acetone is a colorless, flammable liquid that is commonly used as a solvent in various industries, including the medical field. In the medical field, acetone is primarily used as a topical anesthetic to numb the skin before procedures such as injections or minor surgeries. It is also used as a solvent to dissolve certain medications, such as insulin, and to clean medical equipment. Acetone is not typically used internally in medicine, as it can be toxic if ingested in large amounts.
2-Propanol, also known as isopropyl alcohol or rubbing alcohol, is a clear, colorless, flammable liquid with a strong odor. It is commonly used as a disinfectant, antiseptic, and solvent in the medical field. In the medical field, 2-propanol is used to disinfect surfaces and equipment, as well as to clean wounds and skin. It is also used as a preservative in some medications and as a solvent in the preparation of certain medical solutions. However, it is important to note that 2-propanol can be toxic if ingested or inhaled in large quantities. It can cause respiratory and central nervous system depression, as well as liver and kidney damage. Therefore, proper handling and storage of 2-propanol are essential to prevent accidental exposure and toxicity.
Acetoacetates are a group of organic compounds that contain the functional group -COOCH3. They are formed as intermediates in the metabolism of fatty acids and are involved in the production of ketone bodies, which are used as a source of energy by the liver and other tissues in the body. In the medical field, acetoacetates are often used as a diagnostic tool to measure the body's ability to produce ketone bodies, which can be an indicator of certain medical conditions such as diabetes, liver disease, and certain types of cancer. They are also used as a precursor in the synthesis of other compounds, such as acetoacetic esters, which have applications in the pharmaceutical industry.
Butanones, also known as methyl ethyl ketone (MEK) and butyl acetate, are organic compounds that are commonly used in the medical field as solvents and as ingredients in various medical products. MEK is a colorless liquid with a sweet, fruity odor that is used as a solvent in the production of pharmaceuticals, cosmetics, and other medical products. It is also used as a cleaning agent and as a solvent for removing paint and other coatings. Butyl acetate is a colorless liquid with a sweet, fruity odor that is used as a solvent in the production of pharmaceuticals, cosmetics, and other medical products. It is also used as a flavoring agent in food and beverages. Both MEK and butyl acetate are considered to be relatively safe when used in the proper concentrations and under controlled conditions. However, exposure to high concentrations of these compounds can cause irritation of the eyes, nose, and throat, as well as headaches, dizziness, and nausea. In some cases, prolonged or repeated exposure to these compounds may also cause more serious health effects, such as liver and kidney damage.
1-Propanol, also known as n-propanol or propyl alcohol, is a type of alcohol that is commonly used in the medical field as a topical anesthetic and antiseptic. It is a clear, colorless liquid with a distinctive odor and is often used to numb the skin before procedures such as injections or minor surgeries. In addition to its use as a topical anesthetic, 1-propanol is also used as a disinfectant and antiseptic to clean wounds and prevent infection. It is effective against a wide range of bacteria, viruses, and fungi, and is often used in combination with other antiseptic agents to enhance its effectiveness. However, it is important to note that 1-propanol can be toxic if ingested or inhaled in large quantities, and can cause serious health problems such as respiratory depression, central nervous system depression, and even death. As such, it is important to use 1-propanol and other alcohols safely and according to proper guidelines to minimize the risk of adverse effects.
Plant extracts refer to the active compounds or bioactive molecules that are extracted from plants and used in the medical field for various therapeutic purposes. These extracts are obtained through various extraction methods, such as solvent extraction, steam distillation, and cold pressing, and can be used in the form of powders, liquids, or capsules. Plant extracts have been used for centuries in traditional medicine and are now widely used in modern medicine as well. They are used to treat a wide range of conditions, including inflammation, pain, anxiety, depression, and cancer. Some examples of plant extracts used in medicine include aspirin (extracted from willow bark), quinine (extracted from cinchona bark), and morphine (extracted from opium poppy). Plant extracts are also used in the development of new drugs and therapies. Researchers extract compounds from plants and test them for their potential therapeutic effects. If a compound shows promise, it can be further developed into a drug that can be used to treat a specific condition. It is important to note that while plant extracts can be effective in treating certain conditions, they can also have side effects and may interact with other medications. Therefore, it is important to consult with a healthcare professional before using plant extracts as a form of treatment.
Butanols are a group of organic compounds that contain a butyl group (-C4H9) and one or more hydroxyl groups (-OH). They are commonly used as solvents, fuels, and precursors for the production of various chemicals. In the medical field, butanols have been studied for their potential use as anesthetic agents. They have been found to have a rapid onset of action, a relatively short duration of action, and a low incidence of adverse effects compared to other anesthetic agents. However, they have not been widely used in clinical practice due to concerns about their toxicity and potential for abuse. Butanols have also been studied for their potential use in the treatment of certain medical conditions, such as liver disease and cancer. For example, butanol has been shown to have anti-inflammatory and anti-cancer effects in laboratory studies, and it is being investigated as a potential treatment for liver fibrosis and hepatocellular carcinoma. However, more research is needed to determine the safety and efficacy of butanol for these indications.
In the medical field, ketones are organic compounds that are produced when the body breaks down fatty acids for energy. They are typically produced in the liver and are released into the bloodstream as a result of starvation, diabetes, or other conditions that cause the body to use fat as its primary source of energy. Ketones are often measured in the blood or urine as a way to diagnose and monitor certain medical conditions, such as diabetes or ketoacidosis. High levels of ketones in the blood or urine can indicate that the body is not getting enough insulin or is not using glucose effectively, which can be a sign of diabetes or other metabolic disorders. In some cases, ketones may be used as a treatment for certain medical conditions, such as epilepsy or cancer. They may also be used as a source of energy for people who are unable to consume carbohydrates due to certain medical conditions or dietary restrictions.
Carboxy-lyases are a class of enzymes that catalyze the cleavage of carbon-carbon bonds in organic molecules. These enzymes typically use a carboxyl group as a leaving group, resulting in the formation of two smaller molecules. Carboxy-lyases are involved in a variety of metabolic pathways, including the breakdown of amino acids, fatty acids, and carbohydrates. They are also involved in the biosynthesis of certain compounds, such as vitamins and hormones. In the medical field, carboxy-lyases are of interest because they play a role in the metabolism of drugs and other xenobiotics, and may be targeted for the development of new therapeutic agents.
Methanol is a colorless, flammable liquid that is commonly used as a solvent in various industries, including the pharmaceutical industry. In the medical field, methanol is used as a chemical intermediate in the production of various drugs and as a solvent for various medications. It is also used as a denaturant for ethanol, which is used as a disinfectant and antiseptic. However, methanol is highly toxic and can cause serious health problems if ingested or inhaled in large quantities. Ingestion of methanol can lead to symptoms such as nausea, vomiting, headache, dizziness, and even blindness or death. Therefore, it is important to handle methanol with care and to follow proper safety protocols when working with this substance.
In the medical field, pentanones are a class of organic compounds that contain a five-carbon chain with a ketone functional group. They are a subclass of ketones and are characterized by the presence of a carbonyl group (C=O) at one end of the carbon chain and a methyl group (CH3) at the other end. Pentanones are commonly used as solvents, intermediates in chemical synthesis, and as fragrance ingredients. Some pentanones have been studied for their potential medicinal properties, including anti-inflammatory, anti-bacterial, and anti-cancer effects. However, more research is needed to fully understand their potential therapeutic applications. One example of a pentanone is acetone, which is a common solvent used in many medical and laboratory settings. It is also a natural byproduct of metabolism and is exhaled in small amounts through the breath. Other examples of pentanones include 2-pentanone, 3-pentanone, and 4-pentanone.
I'm sorry, but I couldn't find any information on "Picrates" in the medical field. It's possible that you may have misspelled the term or that it is not commonly used in medicine. Can you please provide more context or clarify your question?
Acetone
Acetone cyanohydrin
Acetone carboxylase
Acetone (album)
Acetone (disambiguation)
Acetone imine
Acetone (band)
Acetone hydrazone
Acetone peroxide
Acetone oxime
Acetone thiosemicarbazone
Ace Tone
Acetone azine
Deuterated acetone
Acetone (data page)
Arthur and the Acetone
Acetone-butanol-ethanol fermentation
Mesityl oxide
Diacetone alcohol
History of biotechnology
Chiral analysis
Hydrazine
Nile red
Clonewheel organ
Byron McKeeby
Azine
Who Are You Now (album)
Vehicle (The Clean album)
Vapour density
Hydrazone
Acetone | ToxFAQs™ | ATSDR
Acetone poisoning: MedlinePlus Medical Encyclopedia
Toxicological Profile for Acetone | Peer Review Agenda | ATSDR
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Levels of acetone7
- Low levels of acetone are produced naturally by the human body, and some health conditions can cause these levels to increase. (cdc.gov)
- Noticing these signals can help you avoid exposure to damaging levels of acetone. (cdc.gov)
- Low levels of acetone are in the air, so most people are exposed to very small amounts through breathing, but these are rarely at levels that are harmful to your health. (cdc.gov)
- Workers in certain industries, such as commercial painting, plastic manufacturing, household cleaning, and beauty salons, may be exposed by breathing air with higher levels of acetone in the workplace. (cdc.gov)
- Swallowing very high levels of acetone can result in unconsciousness and damage to the skin in your mouth. (cdc.gov)
- The smell and respiratory irritation or burning eyes that occur from moderate levels are excellent warning signs that can help you avoid breathing damaging levels of acetone. (cdc.gov)
- According to ATSDR, workers in certain industries such as commercial painting, plastic manufacturing, household cleaning, and beauty salons may be exposed to higher levels of acetone in the air in the workplace. (aiha.org)
Profile for acetone3
- Toxicological profile for acetone. (medlineplus.gov)
- A new draft toxicological profile for acetone is now available for review and public comment from the Agency for Toxic Substances and Disease Registry. (aiha.org)
- The draft toxicological profile for acetone is available for download from the ATSDR website . (aiha.org)
Solvent10
- Acetone is miscible with water and serves as an important organic solvent in industry, home, and laboratory. (wikipedia.org)
- Acetone is a solvent for ABS and makes it pliable. (instructables.com)
- Suncoat provides natural, acetone-free nail polish removers as alternatives to chemical solvent-based options. (suncoatproducts.com)
- Acetone is an explicit solvent with a nail polish smell, composed of carbon, hydrogen, and oxygen atoms. (simplesolvents.com)
- Consuming acetone is unlikely to intoxicate you because nature already produces the solvent . (simplesolvents.com)
- Many industries also use the solvent because it's cheap to acquire, and therefore you'll find acetone in tobacco smoke, vehicle exhaust, and landfill sites. (simplesolvents.com)
- Acetone is colorless solvent, that is miscible with water. (frendsbeauty.com)
- High-purity, transparent acetone solvent with high diluting power for polyester resins, paints, enamels and solvent-based varnishes. (makerex.es)
- A one-step deconstruction-separation organosolv fractionation of lignocellulosic biomass using acetone/phenoxyethanol/water ternary solvent system. (bvsalud.org)
- A novel ternary solvent system for organosolv fractionation of lignocellulosic biomass , named APW process, which is composed of acetone , phenoxyethanol and water with the advantages of monophasic deconstruction and biphasic separation of components was developed. (bvsalud.org)
Pure acetone4
- Wise Bread reader Kip Kay told us that by adding pure acetone into his gas tank, his car now gets 10 extra miles per gallon . (wisebread.com)
- Nailite's 100% Pure Acetone are the professional's number one choice for quality and value. (nailiteinc.com)
- Pure acetone is the quickest and most effective product to remove nail polish. (nailiteinc.com)
- Pure Acetone can be used to dissolve nail glue, UV gel and artificial nails. (nailiteinc.com)
Contain acetone6
- You may be exposed to acetone by using products that contain acetone (such as nail polish remover) or being in enclosed environments where these products are used. (cdc.gov)
- Always follow directions on the label when using and storing products that contain acetone. (cdc.gov)
- Do not use products that contain acetone near open flames or hot surfaces. (cdc.gov)
- Store products that contain acetone in a cool, well-ventilated place, away from direct heat. (cdc.gov)
- Other products may also contain acetone. (medlineplus.gov)
- Exposure to acetone results mostly from breathing air, drinking water, or coming in contact with products or soil that contain acetone. (cdc.gov)
Contact with acetone can cause2
- Skin contact with acetone can cause your skin to become dry, irritated, and cracked. (cdc.gov)
- Health effects associated with breathing high amounts of acetone during a short period of time can include headaches, confusion, nausea, racing pulse, and unconsciousness, and skin contact with acetone can cause dryness, irritation, and cracking. (aiha.org)
Classified acetone for carcinogenicity2
- The International Agency for Research on Cancer (IARC) and National Toxicology Program (NTP) have not classified acetone for carcinogenicity. (cdc.gov)
- The Department of Health and Human Services, the International Agency for Research on Cancer, and the Environmental Protection Agency (EPA) have not classified acetone for carcinogenicity. (cdc.gov)
Amount of acetone4
- Breathing a moderate to high amount of acetone can also cause nose, throat, lung, and eye irritation. (cdc.gov)
- There are tests available to measure the amount of acetone in your breath, blood, and urine. (cdc.gov)
- While these tests can tell you how much acetone is in your body, it's important to remember that the amount of acetone that occurs naturally in the body varies from person to person. (cdc.gov)
- The second part of the hypothesis was correct, a small amount of acetone, readily diffused, would soften parts a given amount then stop. (instructables.com)
Happens to acetone2
Toxicological1
- There is no evidence in the available toxicological data that acetone presents an IDLH hazard below the lower explosive limit (LEL) of 25,000 ppm. (cdc.gov)
Dissolve3
- Acetone is used by humans to dissolve other substances and produce plastics, paints and coatings, cleaning products, and personal care products. (cdc.gov)
- Acetone won't dissolve paper the same as water so the paper towel won't soften as it would when dampened with water. (instructables.com)
- Clipping your nails will help the acetone dissolve the acrylics more easily. (wikihow.com)
Amounts7
- Breathing or swallowing high amounts of acetone over a short period of time can cause headaches, confusion, nausea, racing pulse, changes in the size and amount of blood cells, unconsciousness (passing out), or coma. (cdc.gov)
- Accidentally drinking small amounts of acetone/nail polish remover is unlikely to harm you as an adult. (medlineplus.gov)
- Exposure to moderate-to-high amounts of acetone can irritate your eyes and respiratory system, and make you dizzy. (cdc.gov)
- The more acetone in a chamber will produce faster results but in small amounts there will be a limit to the softening. (instructables.com)
- The first part of the hypothesis was wrong, having large amounts of acetone in a chamber didn't result in softer parts, the acetone had to be diffused. (instructables.com)
- Small amounts of acetone will process parts to set softness then stop. (instructables.com)
- High amounts of acetone will process parts quickly but the process must be halted to avoid over processing the parts. (instructables.com)
Flammable2
- Also, it should be noted that acetone vapors are also flammable. (makezine.com)
- Acetone is highly flammable and produces potent fumes. (wikihow.com)
Exposure6
- A strong scent of acetone and irritation in your eyes, nose, and throat are warning signs of moderate exposure. (cdc.gov)
- It is not known if long-term exposure to acetone affects people in these ways. (cdc.gov)
- Tests for acetone exposure must be performed within 2-3 days after you have been exposed, because acetone leaves your body within a few days of entering it. (cdc.gov)
- How can I protect my family from acetone exposure? (cdc.gov)
- Below are symptoms of acetone poisoning or exposure in different parts of the body. (medlineplus.gov)
- The agency's information sheet on acetone advises that a strong scent of acetone and irritation of the eyes, nose, and throat are "warning signs of moderate exposure. (aiha.org)
Ketone bodies2
- Ketogenic diets that increase ketone bodies (acetone, β-hydroxybutyric acid and acetoacetic acid) in the blood are used to counter epileptic attacks in children who suffer from refractory epilepsy. (wikipedia.org)
- Acetoacetate, beta-hydroxybutyrate, and acetone are ketone bodies. (medscape.com)
Nail polish5
- Acetone is the active ingredient in nail polish remover. (wisebread.com)
- Instead of substituting acetone with other harsh chemicals, we employ plant-based ingredients sourced from corn and soybeans to entirely replace acetone within a standard nail polish remover bottle. (suncoatproducts.com)
- Has anyone done the distillation for non-acetone nail polish remover? (sciencemadness.org)
- Love Your Nails nail polish remover towelettes are acetone free and will not dry out nails. (barielle.com)
- makes the breath smell like nail polish remover (acetone). (msdmanuals.com)
Vapors1
- After being removed from the acetone vapors for a few hours the plastic was back to the same hardness as before. (instructables.com)
Breath3
- Acetone is the cause of the sweet odor on the breath in persons with ketoacidosis. (medscape.com)
- Urinary acetoacetate and breath acetone assessments are good predictors of ketosis. (medscape.com)
- Breath acetone analysis is a noninvasive test and is usually associated with minimal patient discomfort. (medscape.com)
Dimethyl ketone1
- Acetone (2-propanone or dimethyl ketone) is an organic compound with the formula (CH3)2CO. (wikipedia.org)
Solvents1
- Acetone and denatured alcohol are transparent and colorless solvents used for cleaning and grease removal. (simplesolvents.com)
Landfills2
Denatured alcohol6
- Just use your acetone (or try denatured alcohol) string in place of the torch. (makezine.com)
- Acetone Vs. Denatured Alcohol: How Are They Different? (simplesolvents.com)
- Below you'll find out all about acetone and denatured alcohol . (simplesolvents.com)
- Industries add artificial colors to help advertise acetone and denatured alcohol as non-consumable products per regulations. (simplesolvents.com)
- You can use acetone or denatured alcohol for degreasing, cleaning, or paint thinning. (simplesolvents.com)
- Be careful not to drink denatured alcohol or acetone as the substances cause toxicity, which could be fatal. (simplesolvents.com)
Acetonitrile1
- Acetone potentiation of acute acetonitrile toxicity in rats. (cdc.gov)
Irritation1
- However, reports say that acetone causes nose, throat, and skin irritation, and you should therefore never ingest it. (simplesolvents.com)
Toxicity1
- The physiological principles governing the action of acetone together with determination of toxicity. (cdc.gov)
Exposures1
- Effects of short, high-concentration exposures to acetone as determined by observation in the work area. (cdc.gov)
Distillation2
- Acetone was first produced by Andreas Libavius in 1606 by distillation of lead(II) acetate. (wikipedia.org)
- Previously, acetone was produced by the dry distillation of acetates, for example calcium acetate in ketonic decarboxylation. (wikipedia.org)
Flames1
- Make sure the room is well ventilated, and keep the acetone away from heat or sources of flames. (wikihow.com)
Environmental Protec1
- The U.S. Environmental Protection Agency (EPA) has concluded that there is not sufficient evidence to assess whether acetone is carcinogenic (causing cancer) to humans. (cdc.gov)
Occurs1
- Acetone discharge occurs in expired air and in urine. (medscape.com)
Acetic1
- In 1833, French chemists Antoine Bussy and Michel Chevreul decided to name acetone by adding the suffix -one to the stem of the corresponding acid (viz, acetic acid) just as a similarly prepared product of what was then confused with the margaric acid was named margarone. (wikipedia.org)
Enters1
- If you are exposed to acetone, it enters your blood, which carries it to all organs in the body. (cdc.gov)
Organic2
- From the 17th century and before modern developments in organic chemistry nomenclature, acetone was given many different names. (wikipedia.org)
- It is simple acetone, a nonhazardous organic chemical. (wisebread.com)
Products3
- Acetone is a chemical used in many household products. (medlineplus.gov)
- This article discusses poisoning from swallowing acetone-based products. (medlineplus.gov)
- Acetone damages some plastic items such as PVC and polystyrene as they are manufactured using acetone or acetone-like products. (simplesolvents.com)
Produces1
- For example, the body produces acetone by metabolizing fat, while trees and plants produce it when they burn down. (simplesolvents.com)
Water8
- Acetone moves from the air into water and soil by rain and snow, and moves quickly from water and soil back into the air. (cdc.gov)
- Acetone is broken down by microbes or chemicals in water and soil. (cdc.gov)
- You may be exposed by drinking water or eating food that is contaminated with acetone. (cdc.gov)
- Acetone is broken down in water and soil, but the time required for this to happen varies. (cdc.gov)
- Water-acetone mixture was used as a dispersion medium to synthesize a PMMA opal structure. (kirensky.ru)
- Morphology features, IR vibrational spectra and glass transition temperatures of the PMMA nanospheres formed in the water-acetone dispersion medium (nanospheres A) have been studied comparing with the same prepared in distilled water solution without acetone (nanospheres B). A dependence of a shrinkage degree of the nanoparticles on the acetone volume has been investigated. (kirensky.ru)
- The nanospheres A are less flexible and soft as compared to the nanospheres B. Additionally, an ability of the PMMA nanoparticles fabricated in the water-acetone dispersion medium to form the ordered opal structures is demonstrated to be the similar to the nanospheres B. (kirensky.ru)
- Through fractionation of amorpha as a case study , a monophasic APW solution ( acetone /phenoxyethanol/ water = 5114, volume ratio) with the best lignin affinity was constructed based on Hansen solubility parameters . (bvsalud.org)
Chemicals1
- About half of the total acetone in air is broken down by sunlight or other chemicals within 22 days. (cdc.gov)
Surfaces2
- These were all scraps of a failed batch with particularly rough surfaces, perfect for acetone smoothing. (instructables.com)
- For example, you'll find that acetone is good for removing stubborn stains on porcelain, paint, and melted plastic on surfaces. (simplesolvents.com)
Processes3
- Acetone is produced and disposed of in the human body through normal metabolic processes. (wikipedia.org)
- In the cumene process, benzene is alkylated with propylene to produce cumene, which is oxidized by air to produce phenol and acetone: Other processes involve the direct oxidation of propylene (Wacker-Hoechst process), or the hydration of propylene to give 2-propanol, which is oxidized (dehydrogenated) to acetone. (wikipedia.org)
- Industrial processes contribute more acetone to the environment than natural processes. (cdc.gov)
Skin2
- Acetone is absorbed through the skin quite readily. (makezine.com)
- Acetone is hard on skin, so it's important to protect your fingers. (wikihow.com)
Nails2
- We've put together a handy guide to removing acrylic nails with acetone, dental floss, and an electric nail filer, so you can free your fingers at home. (wikihow.com)
- Clip your nails and wrap them in acetone -soaked cotton balls and tin foil. (wikihow.com)
High1
- Time-lapse video showed the plastic softening then becoming weak with the high concentration of acetone. (instructables.com)
Adhesives1
- In addition, acetone helps with the removal of adhesives and vinyl resins. (simplesolvents.com)
Chemical2
Result1
- as a result, acetone production is tied to phenol production. (wikipedia.org)
Include1
- Names derived from mesit include mesitylene and mesityl oxide which were first synthesised from acetone. (wikipedia.org)
Search1
- Do a simple Google Patent search for ' acetone fuel efficiency ' and see the results for yourself. (wisebread.com)