Protein Kinase C
Electrophoresis, Cellulose Acetate
Acetyl Coenzyme A
Fatty Acids, Volatile
Citric Acid Cycle
Molecular Sequence Data
Contraceptive Agents, Female
Dose-Response Relationship, Drug
Naphthol AS D Esterase
Magnetic Resonance Spectroscopy
Chromatography, High Pressure Liquid
Tumor Cells, Cultured
Gas Chromatography-Mass Spectrometry
RNA, Ribosomal, 16S
Chromatography, Thin Layer
Rats, Inbred Strains
Gene Expression Regulation
Protein Kinase C-alpha
Amino Acid Sequence
Gram-Negative Anaerobic Bacteria
Carboxylic Ester Hydrolases
Vasopressin stimulation of acetate incorporation into lipids in a dimethylbenz(a)anthracene-induced rat mammary tumor cell line. (1/4860)In a preliminary report we described the effects of rat prolactin on the incorporation of [14C]acetate into lipids by a cell line from a dimethylbenz(a)anthracene-induced rat mammary tumor. The characteristics of the response to prolactin were very similar to those described for the normal rat mammary gland; namely, insulin was required for full expression of the response, maximal activity was not seen until 36 hr after the addition of the hormones, and growth hormone was able to elicit the same response. However, we were unable to detect binding of 125I-labeled prolactin to these cells, and furthermore, other more purified prolactin preparations were inactive. Upon further investigation we discovered that the activity resided in a low-molecular-weight fraction of the rat prolactin B-1 preparation and was probably either vasopressin or oxytocin or both. These data suggest the possibility that vasopressin may play a role in rodent mammary tumorigenesis. (+info)
Analysis of gabapentin in serum and plasma by solid-phase extraction and gas chromatography-mass spectrometry for therapeutic drug monitoring. (2/4860)A simple method for the determination of gabapentin (Neurontin) is described. The method uses solid-phase extraction by disk column and derivatization followed by gas chromatographic-mass spectrometric analysis. The single-step derivatization with MTBSTFA produces a t-BDMS derivative of both the carboxylic and amine moieties of the molecule. Each step of the procedure was optimized to assure reliable performance of the method. The assay limit of detection was 0.1 microg/mL with a linear range from 1.0 to 35 microg/mL. Within-run (n = 3) and between-run (n = 40) coefficients of variation were less than 8.2 and 15.9%, respectively. The method has proven reliable in routine production for more than a year, producing clean chromatography with unique ion fragments, consistent ion mass ratios, and no interferences. Statistical analysis of the gabapentin concentrations measured in 1020 random specimens over a 2-month period showed a mean concentration of 6.07 microg/mL with a standard deviation of 5.28. (+info)
Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats. (3/4860)Repetitive ectopic discharges from injured afferent nerves play an important role in initiation and maintenance of neuropathic pain. Gabapentin is effective for treatment of neuropathic pain but the sites and mechanisms of its antinociceptive actions remain uncertain. In the present study, we tested a hypothesis that therapeutic doses of gabapentin suppress ectopic afferent discharge activity generated from injured peripheral nerves. Mechanical allodynia, induced by partial ligation of the sciatic nerve in rats, was determined by application of von Frey filaments to the hindpaw. Single-unit afferent nerve activity was recorded proximal to the ligated sciatic nerve site. Intravenous gabapentin, in a range of 30 to 90 mg/kg, significantly attenuated allodynia in nerve-injured rats. Furthermore, gabapentin, in the same therapeutic dose range, dose-dependently inhibited the ectopic discharge activity of 15 injured sciatic afferent nerve fibers through an action on impulse generation. However, the conduction velocity and responses of 12 normal afferent fibers to mechanical stimulation were not affected by gabapentin. Therefore, this study provides electrophysiological evidence that gabapentin is capable of suppressing the ectopic discharge activity from injured peripheral nerves. This action may contribute, at least in part, to the antiallodynic effect of gabapentin on neuropathic pain. (+info)
Pharmacology of LY315920/S-5920, [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti-inflammatory drugs, SPI. (4/4860)LY315920 is a potent, selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2). In a chromogenic isolated enzyme assay, LY315920 inhibited sPLA2 activity with an IC50 of 9 +/- 1 nM or 7.3 x 10(-6) mole fraction, which approached the stiochiometric limit of this assay. The true potency of LY315920 was defined using a deoxycholate/phosphatidylcholine assay with a mole fraction of 1.5 x 10(-6). LY315920 was 40-fold less active against human, group IB, pancreatic sPLA2 and was inactive against cytosolic PLA2 and the constitutive and inducible forms of cyclooxygenase. Human sPLA2-induced release of thromboxane A2 (TXA2) from isolated guinea pig lung bronchoalveolar lavage cells was inhibited by LY315920 with an IC50 of 0.79 microM. The release of TXA2 from these cells by N-formyl-methionyl-leucyl-phenylalanine or arachidonic acid was not inhibited. The i.v. administration of LY315920, 5 min before harvesting the bronchoalveolar lavage cells, resulted in the inhibition of sPLA2-induced production of TXA2 with an ED50 of 16.1 mg/kg. Challenge of guinea pig lung pleural strips with sPLA2 produced contractile responses that were suppressed in a concentration-dependent manner by LY315920 with an apparent KB of 83 +/- 14 nM. Contractile responses induced by arachidonic acid were not altered. Intravenous or oral administration of LY315920 to transgenic mice expressing the human sPLA2 protein inhibited serum sPLA2 activity in a dose-related manner over a 4-h time course. LY315920 is a potent and selective sPLA2 inhibitor and represents a new class of anti-inflammatory agent designated SPI. This agent is currently undergoing clinical evaluation and should help to define the role of sPLA2 in various inflammatory disease states. (+info)
Anti-ulcer effects of 4'-(2-carboxyetyl) phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride (cetraxate) on various experimental gastric ulcers in rats. (5/4860)Anti-ulcer effects of cetraxate, a new compound possessing anti-plasmin, anti-casein and anti-trypsin actions were investigated by using experimental gastric ulcer models in rats. Cetraxate, 300 mg/kg p.o. showed significant inhibitory effects of 65.3%, 70.0%, 30.2%, and 67.1% against aucte types of ulcers producing by aspirin, phenylbutazone, indomethacin, and pyloric ligature (Shay's ulcer), respectively. These effects were greater than those obtained by gefarnate and aluminum sucrose sulfate may be mainly attributed to the protecting action of this drug on gastric mucosa. Ctraxate further revealed remarkable inhibitory effects on chronic types of ulcers produced by acetic acid, clamping, and clamping-cortisone. In acetic acid ulcer in particular, cetraxate was found to have a dose-dependent inhibitory effect at doses over 50 mg/kg. Of test drugs including L-glutamine and methylmethionine sulfonium chloride, cetraxate showed the most remarkable inhibitory effect on beta-glucuronidase activity in ulcer tissue of these three types of ulcers. These findings suggest that cetraxate may prevent the connective tissue in the ulcer location from decomposition due to lysosomal enzymes such as beta-glucuronidase, thereby accelerating the recovery from ulcer. (+info)
Isocitrate lyase of Ashbya gossypii--transcriptional regulation and peroxisomal localization. (6/4860)The isocitrate lyase-encoding gene AgICL1 from the filamentous hemiascomycete Ashbya gossypii was isolated by heterologous complementation of a Saccharomyces cerevisiae icl1d mutant. The open reading frame of 1680 bp encoded a protein of 560 amino acids with a calculated molecular weight of 62584. Disruption of the AgICL1 gene led to complete loss of AgIcl1p activity and inability to grow on oleic acid as sole carbon source. Compartmentation of AgIcl1p in peroxisomes was demonstrated both by Percoll density gradient centrifugation and by immunogold labeling of ultrathin sections using specific antibodies. This fitted with the peroxisomal targeting signal AKL predicted from the C-terminal DNA sequence. Northern blot analysis with mycelium grown on different carbon sources as well as AgICL1 promoter replacement with the constitutive AgTEF promoter revealed a regulation at the transcriptional level. AgICL1 was subject to glucose repression, derepressed by glycerol, partially induced by the C2 compounds ethanol and acetate, and fully induced by soybean oil. (+info)
Mechanism of citrate metabolism in Lactococcus lactis: resistance against lactate toxicity at low pH. (7/4860)Measurement of the flux through the citrate fermentation pathway in resting cells of Lactococcus lactis CRL264 grown in a pH-controlled fermentor at different pH values showed that the pathway was constitutively expressed, but its activity was significantly enhanced at low pH. The flux through the citrate-degrading pathway correlated with the magnitude of the membrane potential and pH gradient that were generated when citrate was added to the cells. The citrate degradation rate and proton motive force were significantly higher when glucose was metabolized at the same time, a phenomenon that could be mimicked by the addition of lactate, the end product of glucose metabolism. The results clearly demonstrate that citrate metabolism in L. lactis is a secondary proton motive force-generating pathway. Although the proton motive force generated by citrate in cells grown at low pH was of the same magnitude as that generated by glucose fermentation, citrate metabolism did not affect the growth rate of L. lactis in rich media. However, inhibition of growth by lactate was relieved when citrate also was present in the growth medium. Citrate did not relieve the inhibition by other weak acids, suggesting a specific role of the citrate transporter CitP in the relief of inhibition. The mechanism of citrate metabolism presented here provides an explanation for the resistance to lactate toxicity. It is suggested that the citrate metabolic pathway is induced under the acidic conditions of the late exponential growth phase to make the cells (more) resistant to the inhibitory effects of the fermentation product, lactate, that accumulates under these conditions. (+info)
Nitrate-dependent regulation of acetate biosynthesis and nitrate respiration by Clostridium thermoaceticum. (8/4860)Nitrate has been shown to shunt the electron flow in Clostridium thermoaceticum from CO2 to nitrate, but it did not influence the levels of enzymes involved in the Wood-Ljungdahl pathway (J. M. Frostl, C. Seifritz, and H. L. Drake, J. Bacteriol. 178:4597-4603, 1996). Here we show that under some growth conditions, nitrate does in fact repress proteins involved in the Wood-Ljungdahl pathway. The CO oxidation activity in crude extracts of nitrate (30 mM)-supplemented cultures was fivefold less than that of nitrate-free cultures, while the H2 oxidation activity was six- to sevenfold lower. The decrease in CO oxidation activity paralleled a decrease in CO dehydrogenase (CODH) protein level, as confirmed by Western blot analysis. Protein levels of CODH in nitrate-supplemented cultures were 50% lower than those in nitrate-free cultures. Western blots analyses showed that nitrate also decreased the levels of the corrinoid iron-sulfur protein (60%) and methyltransferase (70%). Surprisingly, the decrease in activity and protein levels upon nitrate supplementation was observed only when cultures were continuously sparged. Northern blot analysis indicates that the regulation of the proteins involved in the Wood-Ljungdahl pathway by nitrate is at the transcriptional level. At least a 10-fold decrease in levels of cytochrome b was observed with nitrate supplementation whether the cultures were sparged or stoppered. We also detected nitrate-inducible nitrate reductase activity (2 to 39 nmol min-1 mg-1) in crude extracts of C. thermoaceticum. Our results indicate that nitrate coordinately represses genes encoding enzymes and electron transport proteins in the Wood-Ljungdahl pathway and activates transcription of nitrate respiratory proteins. CO2 also appears to induce expression of the Wood-Ljungdahl pathway genes and repress nitrate reductase activity. (+info)
Papillomas can occur anywhere on the body, but they are most commonly found on the face, neck, and scalp. They may appear as small bumps or growths that look like a wart. In some cases, papillomas may be associated with human papillomavirus (HPV) infection.
Papillomas are typically diagnosed through a physical examination of the affected area. In some cases, a biopsy may be performed to confirm the diagnosis and rule out other potential causes. Treatment for papillomas usually involves removal of the growth through a minor surgical procedure or cryotherapy (freezing).
Papillomas are not cancerous and do not typically pose any long-term health risks. However, they may be unsightly and can cause psychological distress for some people. In these cases, treatment may be sought for cosmetic reasons. It is important to note that papillomas should not be confused with squamous cell carcinoma, a type of skin cancer that can resemble a papilloma in appearance but has the potential to be more aggressive and harmful.
There are several types of skin neoplasms, including:
1. Basal cell carcinoma (BCC): This is the most common type of skin cancer, and it usually appears as a small, fleshy bump or a flat, scaly patch. BCC is highly treatable, but if left untreated, it can grow and invade surrounding tissue.
2. Squamous cell carcinoma (SCC): This type of skin cancer is less common than BCC but more aggressive. It typically appears as a firm, flat, or raised bump on sun-exposed areas. SCC can spread to other parts of the body if left untreated.
3. Melanoma: This is the most serious type of skin cancer, accounting for only 1% of all skin neoplasms but responsible for the majority of skin cancer deaths. Melanoma can appear as a new or changing mole, and it's essential to recognize the ABCDE signs (Asymmetry, Border irregularity, Color variation, Diameter >6mm, Evolving size, shape, or color) to detect it early.
4. Sebaceous gland carcinoma: This rare type of skin cancer originates in the oil-producing glands of the skin and can appear as a firm, painless nodule on the forehead, nose, or other oily areas.
5. Merkel cell carcinoma: This is a rare and aggressive skin cancer that typically appears as a firm, shiny bump on the skin. It's more common in older adults and those with a history of sun exposure.
6. Cutaneous lymphoma: This type of cancer affects the immune system and can appear as a rash, nodules, or tumors on the skin.
7. Kaposi sarcoma: This is a rare type of skin cancer that affects people with weakened immune systems, such as those with HIV/AIDS. It typically appears as a flat, red or purple lesion on the skin.
While skin cancers are generally curable when detected early, it's important to be aware of your skin and notice any changes or unusual spots, especially if you have a history of sun exposure or other risk factors. If you suspect anything suspicious, see a dermatologist for an evaluation and potential biopsy. Remember, prevention is key to avoiding the harmful effects of UV radiation and reducing your risk of developing skin cancer.
Symptoms of Canavan disease typically become apparent within the first few months of life and may include:
* Delayed development
* Muscle weakness and stiffness
* Poor coordination and balance
* Vision loss
* Hearing loss
* Respiratory problems
There is no cure for Canavan disease, and treatment is limited to managing the symptoms. Children with the disorder often have a shortened lifespan, typically living into their teenage years or early twenties. The progression of the disease can be slowed with medication and other supportive therapies, but the outcome is generally poor.
Canavan disease is an autosomal recessive disorder, which means that a child must inherit two copies of the mutated gene (one from each parent) in order to develop the condition. If a child inherits only one copy of the mutated gene, they will be a carrier of the disorder but are unlikely to develop symptoms themselves. Carriers have a 25% chance of passing the mutated gene to each of their children.
Canavan disease can be diagnosed through a combination of clinical evaluation, laboratory tests, and imaging studies. Laboratory tests may include measurement of aspartoacylase enzyme activity in white blood cells or analysis of genetic mutations that cause the disorder. Imaging studies such as MRI or CT scans may also be used to evaluate brain development and identify any structural abnormalities.
There is no cure for Canavan disease, but treatment can help manage the symptoms and improve quality of life. Treatment options may include:
* Physical therapy to improve muscle strength and coordination
* Occupational therapy to help with daily activities and fine motor skills
* Speech therapy to improve communication skills
* Seizure medication to control seizures
* Anticonvulsant medication to reduce the frequency and severity of seizures
The prognosis for Canavan disease is generally poor, with most children dying before the age of 2. However, some individuals with milder forms of the disorder may live into their teenage years or even early adulthood. It is important to note that each child's prognosis can vary greatly depending on the severity of their condition and the presence of any other health issues.
Canavan disease can lead to a range of complications, including:
* Seizures: Canavan disease can cause seizures, which can be difficult to control.
* Developmental delays: Children with Canavan disease may experience developmental delays and learning disabilities.
* Intellectual disability: Many individuals with Canavan disease will have intellectual disability.
* Vision loss: Some children with Canavan disease may experience vision loss or blindness.
* Hearing loss: Some children with Canavan disease may experience hearing loss.
* Respiratory problems: Canavan disease can cause respiratory problems, such as sleep apnea and pneumonia.
* Infections: Children with Canavan disease may be more susceptible to infections due to their weakened immune system.
Causes and risk factors:
Canavan disease is caused by a mutation in the ASPA gene, which codes for an enzyme involved in the breakdown of certain fats in the body. This mutation leads to a buildup of these fats in the brain, causing damage to brain cells and leading to the symptoms of the disorder.
There is no known risk factor for Canavan disease, as it is a genetic condition that can occur spontaneously. However, family history may be a factor in some cases, as there is a higher risk of the disorder occurring in individuals with a family history of the condition.
There is no known prevention for Canavan disease, as it is a genetic condition that occurs spontaneously. However, prenatal testing is available for pregnant women who have a family history of the disorder or who are at risk of having an affected child. This testing can help identify whether the fetus has the mutated ASPA gene and confirm a diagnosis of Canavan disease.
Treatment and management:
There is no cure for Canavan disease, and treatment is focused on managing the symptoms and preventing complications. Some of the treatments that may be used to manage the disorder include:
* Physical therapy: To help improve muscle tone and strength.
* Occupational therapy: To help with daily activities and fine motor skills.
* Speech therapy: To help with communication and language development.
* Medications: To control seizures and other symptoms.
* Respiratory support: To help with breathing difficulties.
The prognosis for Canavan disease is poor, as the disorder is progressive and there is no cure. Children with the condition typically have a shortened lifespan, with many passing away before the age of 10. However, with proper management and support, some individuals with Canavan disease may live into their teenage years or even early adulthood.
In conclusion, Canavan disease is a rare and severe genetic disorder that affects the brain and spinal cord. It is caused by mutations in the ASPA gene and can be diagnosed through genetic testing. While there is no cure for the disorder, treatment and management are available to help improve symptoms and quality of life. With proper support and care, individuals with Canavan disease can live fulfilling lives despite their challenges.
Cocarcinogenesis can occur through various mechanisms, such as:
1. Synergistic effects: The combined effect of two or more substances is greater than the sum of their individual effects. For example, smoking and exposure to asbestos can increase the risk of lung cancer more than either factor alone.
2. Antagonism: One substance may counteract the protective effects of another substance, leading to an increased risk of cancer. For example, alcohol consumption may antagonize the protective effects of a healthy diet against liver cancer.
3. Potentiation: One substance may enhance the carcinogenic effects of another substance. For example, smoking can potentiate the carcinogenic effects of exposure to certain chemicals in tobacco smoke.
4. Multistage carcinogenesis: Cocarcinogens can contribute to the development of cancer through multiple stages of carcinogenesis, including initiation, promotion, and progression.
Understanding cocarcinogenesis is important for developing effective cancer prevention strategies and for identifying potential co-carcinogens in our environment and diet. By identifying and avoiding co-carcinogens, we can reduce our risk of cancer and improve our overall health.
Liquid chromatography-tandem mass spectrometry method for measuring vitamin E acetate in bronchoalveolar lavage fluid - PubMed
Vinyl Acetate | ToxFAQs™ | ATSDR
Propylene Glycol Ethers and Their Acetates (91-103) | NIOSH | CDC
ICSC 1445 - tert-BUTYL ACETATE
Isoamyl acetate Definition & Meaning - Merriam-Webster
DailyMed - HYDROCORTISONE ACETATE suppository
DailyMed - DESMOPRESSIN ACETATE tablet
acetate Archives | High Times
DailyMed - FLECAINIDE ACETATE tablet
Piperonyl acetate M20133
Gucci + Cat-Eye Acetate Glasses
DailyMed - ABIRATERONE ACETATE tablet, film coated
1-METHOXY-2-PROPYL ACETATE | Occupational Safety and Health Administration
Vitamin E Acetate Now Directly Linked to Vaping Injury: CDC
Aluminum acetate - brand name list from Drugs.com
Red Glitter Acetate Stud Earrings #A750000418
Uranyl Acetate | AMERICAN ELEMENTS ®
Acetate ion | C2H3O2 | ChemSpider
estradiol acetate oral and enoxaparin subq Drug Interactions - RxList
Neuroprotection with glatiramer acetate: evidence from the PreCISe trial
Calcium Acetate: MedlinePlus Drug Information
Softie Sunglasses | Black Bio-Acetate | Women | Mulberry
Acetate High Waist Fit Jeans - MISS SIXTY
Depot Medroxyprogesterone Acetate Use and the Development and Progression of Uterine Leiomyoma
- With sodium ethylate in ethyl acetate solution it forms the sodium derivative of benzoyl acetone, from which benzoyl acetone, C6H5.CO.CH2.CO.CH3, can be obtained by acidification with acetic acid. (yourdictionary.com)
- Wanklyn have shown that pure ethyl acetate free from alcohol will not react with sodium to produce aceto-acetic ester. (yourdictionary.com)
- This fact sheet answers the most frequently asked health questions (FAQs) about vinyl acetate. (cdc.gov)
- Exposure to vinyl acetate occurs mainly in the workplace. (cdc.gov)
- What is vinyl acetate? (cdc.gov)
- Vinyl acetate is an industrial chemical that is produced in large amounts in the United States. (cdc.gov)
- Vinyl acetate is used to make other industrial chemicals. (cdc.gov)
- Vinyl acetate is also used as a coating in plastic films for food packaging and as a modifier of food starch. (cdc.gov)
- What happens to vinyl acetate when it enters the environment? (cdc.gov)
- Vinyl acetate enters the environment from industries that make, use, or process it. (cdc.gov)
- Vinyl acetate breaks down readily in the environment. (cdc.gov)
- It is not known how long vinyl acetate stays in the soil. (cdc.gov)
- How might I be exposed to vinyl acetate? (cdc.gov)
- Breathing air near a factory that makes or uses vinyl acetate. (cdc.gov)
- Breathing air near a hazardous waste site containing vinyl acetate. (cdc.gov)
- How can vinyl acetate affect my health? (cdc.gov)
- The major effects experienced from breathing high levels of vinyl acetate for a short time are irritated eyes, nose, and throat. (cdc.gov)
- We don't know what the effects are from breathing lower levels of vinyl acetate for a long time. (cdc.gov)
- We also don't know what happens if you ingest vinyl acetate. (cdc.gov)
- Birth defects were not seen in the offspring of animals that were exposed to vinyl acetate in drinking water during their pregnancies. (cdc.gov)
- Vinyl acetate has caused skin irritation and blisters in workers who accidentally spilled it on their skin. (cdc.gov)
- Eye irritation has also been seen when people were exposed to vinyl acetate in the air or through accidents when the chemical went into their eyes. (cdc.gov)
- How likely is vinyl acetate to cause cancer? (cdc.gov)
- The International Agency for Research on Cancer has determined that vinyl acetate is not classifiable as to its carcinogenicity to humans. (cdc.gov)
- There are no human studies on the carcinogenicity of vinyl acetate. (cdc.gov)
- one study showed an increase in tumors of the noses of rats who breathed vinyl acetate, while another study did not show an increase in tumors in rats who drank water containing the chemical. (cdc.gov)
- Is there a medical test to show whether I've been exposed to vinyl acetate? (cdc.gov)
- No tests are available to measure vinyl acetate in the blood, urine, or body tissues. (cdc.gov)
- thus, measurement of these break down products is not useful for determining whether you have been exposed to vinyl acetate. (cdc.gov)
- The Environmental Protection Agency (EPA) requires that discharges or accidental spills into the environment of 5,000 pounds or more of vinyl acetate be reported to the EPA. (cdc.gov)
- The Food and Drug Administration (FDA) has determined that vinyl acetate may be safely used as a coating or a part of a coating that is used in plastic films for food packaging, and as a modifier of food starch. (cdc.gov)
- The American Conference of Governmental Industrial Hygienists (ACGIH) has established an exposure limit of 10 parts of vinyl acetate per million parts of workplace air (10 ppm) for an 8-hour workday, 40-hour workweek. (cdc.gov)
- Vinyl acetate is an industrial chemical that is produced in o Breathing air near a factory that makes or uses vinyl acetate. (cdc.gov)
- It is very flammable and may o Breathing air near a hazardous waste site containing vinyl acetate. (cdc.gov)
- We also don't know o Vinyl acetate enters the environment from industries that what happens if you ingest vinyl acetate. (cdc.gov)
- that were exposed to vinyl acetate in drinking water during o It is not known how long vinyl acetate stays in the soil. (cdc.gov)
- Vinyl acetate has caused skin irritation and blisters in 5,000 pounds or more of vinyl acetate be reported to the workers who accidentally spilled it on their skin. (cdc.gov)
- irritation has also been seen when people were exposed to The Food and Drug Administration (FDA) has deter vinyl acetate in the air or through accidents when the chemi mined that vinyl acetate may be safely used as a coating or cal went into their eyes. (cdc.gov)
- The National Institute for Occupational Safety and There are no human studies on the carcinogenicity of Health (NIOSH) recommends that exposure to vinyl vinyl acetate. (cdc.gov)
- breathed vinyl acetate, while another study did not show an increase in tumors in rats who drank water containing the chemical. (cdc.gov)
- Vinyl acetate breaks down very ppm: Parts per million. (cdc.gov)
- Details for: Butyl acetates. (who.int)
- What is the most important information I should know about zinc acetate? (uofmhealth.org)
- What is zinc acetate? (uofmhealth.org)
- Zinc acetate is usually given to people who have already been treated with a chelating drug to remove copper from the body. (uofmhealth.org)
- Zinc acetate may also be used for other purposes not listed in this medication guide. (uofmhealth.org)
- What should I discuss with my healthcare provider before taking zinc acetate? (uofmhealth.org)
- You should not use zinc acetate if you are allergic to it. (uofmhealth.org)
- You should not breastfeed while taking zinc acetate. (uofmhealth.org)
- Zinc acetate should not be given to a child younger than 10 years old. (uofmhealth.org)
- How should I take zinc acetate? (uofmhealth.org)
- If zinc acetate upsets your stomach, take the medicine between breakfast and lunch. (uofmhealth.org)
- Take zinc acetate regularly to get the most benefit. (uofmhealth.org)
- What should I avoid while taking zinc acetate? (uofmhealth.org)
- You may need to avoid certain foods that can make it harder for your body to absorb zinc acetate. (uofmhealth.org)
- What are the possible side effects of zinc acetate? (uofmhealth.org)
- What other drugs will affect zinc acetate? (uofmhealth.org)
- Other drugs may affect zinc acetate, including prescription and over-the-counter medicines, vitamins, and herbal products. (uofmhealth.org)
- Your pharmacist can provide more information about zinc acetate. (uofmhealth.org)
- Zinc Acetate Dihydrate Tablet-associated Gastric Lesions. (bvsalud.org)
- Objective This study aimed to determine the prevalence and endoscopic features of zinc acetate dihydrate tablet -associated gastric lesions. (bvsalud.org)
- Methods We retrospectively examined the endoscopic features of 47 patients taking zinc acetate dihydrate tablets who underwent esophagogastroduodenoscopy . (bvsalud.org)
- None of the 19 patients who previously underwent esophagogastroduodenoscopy had gastric lesions before starting zinc acetate dihydrate . (bvsalud.org)
- Esophagogastroduodenoscopy was performed after the cessation of zinc acetate dihydrate intake in six patients , and revealed the resolution of gastric lesions. (bvsalud.org)
- Conclusion Gastric lesions were observed in 29 of 47 patients who were taking zinc acetate dihydrate tablets . (bvsalud.org)
- Although the exact pathogenesis is uncertain, we believe that understanding the unique manifestations of this gastric lesion will help physicians manage adverse events in patients taking zinc acetate dihydrate tablets . (bvsalud.org)
- Geuther, who showed that the chief product of the action of sodium on ethyl acetate was a sodium compound of composition C6H903Na, which on treatment with acids gave a colourless, somewhat oily liquid of composition C6H1003. (yourdictionary.com)
- Find similar words to ethyl acetate using the buttons below. (yourdictionary.com)
- The enzyme did not hydrolyse retinyl acetate, cholesteryl acetate and ethyl acetate, thus indicating a high degree of specificity. (who.int)
- This document deals with the propylene glycol ethers most commonly used in industry, namely methoxypropanol, methoxypropyl acetate and dipropylene glycol monomethyl ether. (cdc.gov)
- Domoradzki, J.Y., Brzak, K.A. and Thornton, C.M.: Hydrolysis kinetics of Propylene glycol monomethyl ether acetate in rats in vivo and in rat and human tissues in vitro . (osha.gov)
- Ethylene glycol monoethyl ether (EGEE) and ethylene gly- col monoethyl ether acetate (EGEEA) have been used in a The solvents ethylene glycol monoethyl ether acetate (EGEEA) variety of solvent applications. (cdc.gov)
- Flecainide acetate is an antiarrhythmic drug available in tablets of 50 mg, 100 mg, or 150 mg for oral administration. (nih.gov)
- Flecainide acetate is a white crystalline substance with a pK a of 9.3. (nih.gov)
- Flecainide Acetate Tablets USP also contain the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, pregelatinized starch and sodium stearyl fumarate. (nih.gov)
- In man, flecainide acetate produces a dose-related decrease in intracardiac conduction in all parts of the heart with the greatest effect on the His-Purkinje system (H-V conduction). (nih.gov)
- Flecainide acetate causes a dose-related and plasma-level related decrease in single and multiple PVCs and can suppress recurrence of ventricular tachycardia. (nih.gov)
- In limited studies of patients with a history of ventricular tachycardia, flecainide acetate has been successful 30 to 40% of the time in fully suppressing the inducibility of arrhythmias by programmed electrical stimulation. (nih.gov)
- Flecainide acetate does not usually alter heart rate, although bradycardia and tachycardia have been reported occasionally. (nih.gov)
- Following oral administration, the absorption of flecainide acetate is nearly complete. (nih.gov)
- A reduction in flecainide acetate dosage should be considered when milk is removed from the diet of infants. (nih.gov)
- Each Hydrocortisone Acetate Suppository for rectal administration contains hydrocortisone acetate in a hydrogenated cocoglyceride base. (nih.gov)
- Hydrocortisone acetate is a corticosteroid. (nih.gov)
- The molecular weight of hydrocortisone acetate is 404.50. (nih.gov)
- In normal subjects, about 26 percent of hydrocortisone acetate is absorbed when the hydrocortisone acetate suppository is applied to the rectum. (nih.gov)
- Absorption of hydrocortisone acetate may vary across abraded or inflamed surfaces. (nih.gov)
- Hydrocortisone Acetate Suppositories are indicated for use in inflamed hemorrhoids, post irradiation (factitial) proctitis, as an adjunct in the treatment of chronic ulcerative colitis, cryptitis, other inflammatory conditions of the anorectum, and pruritus ani. (nih.gov)
- Hydrocortisone Acetate Suppositories are contraindicated in those patients with a history of hypersensitivity to any of the components. (nih.gov)
- Hydrocortisone acetate suppositories should only be used during pregnancy if the potential benefit justifies the risk to the fetus. (nih.gov)
- Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from hydrocortisone acetate suppositories, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. (nih.gov)
- Drug abuse and dependence have not been reported in patients treated with Hydrocortisone Acetate Suppositories. (nih.gov)
- Hydrocortisone Acetate Suppositories are easy to open, color coded and available in cartons of 12. (nih.gov)
- Hydrocortisone acetate decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing increased capillary permeability. (medscape.com)
- Calcium acetate is used to control high blood levels of phosphorus in people with kidney disease who are on dialysis (medical treatment to clean the blood when the kidneys are not working properly). (medlineplus.gov)
- Calcium acetate is in a class of medications called phosphate binders. (medlineplus.gov)
- Calcium acetate comes as a capsule, tablet, and a solution (liquid) to take by mouth. (medlineplus.gov)
- Take calcium acetate at around the same times every day. (medlineplus.gov)
- Take calcium acetate exactly as directed. (medlineplus.gov)
- tell your doctor and pharmacist if you are allergic to calcium acetate, any other medications, or any of the ingredients in calcium acetate preparations. (medlineplus.gov)
- Take a fluoroquinolone antibiotic such as ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin, or moxifloxacin (Avelox) at least 2 hours before or 6 hours after taking calcium acetate. (medlineplus.gov)
- Also, take levothyroxine (Euthyrox, Synthroid, Tirosint) at least 4 hours before or 4 hours after taking calcium acetate. (medlineplus.gov)
- Many other medications may also interact with calcium acetate, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. (medlineplus.gov)
- Do not take supplements or antacids containing calcium while taking calcium acetate. (medlineplus.gov)
- Your doctor will probably tell you not to take calcium acetate. (medlineplus.gov)
- If you become pregnant while taking calcium acetate, call your doctor. (medlineplus.gov)
- Calcium acetate may cause side effects. (medlineplus.gov)
- calcium acetate will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. (medscape.com)
- calcium acetate decreases levels of eltrombopag by inhibition of GI absorption. (medscape.com)
- calcium acetate decreases effects of acebutolol by unspecified interaction mechanism. (medscape.com)
- calcium acetate will increase the level or effect of amantadine by Other (see comment). (medscape.com)
- calcium acetate decreases effects of amlodipine by pharmacodynamic antagonism. (medscape.com)
- We investigated the suitability of isotope-dilution liquid chromatography coupled with tandem mass spectrometry for identifying vitamin E acetate (VEA) in bronchoalveolar lavage (BAL) fluid. (nih.gov)
- A study shows both THC-O and vitamin E acetate may convert into a dangerous lung toxin when they are heated in a vape pen. (hightimes.com)
- For the first time, vitamin E acetate has been found in biologic samples obtained from patients with e-cigarette, or vaping, product use associated lung injury (EVALI), federal health officials with the US Centers for Disease Control and Prevention (CDC) said today. (medscape.com)
- Tests on 29 bronchoalveolar lavage (BAL) fluid samples from EVALI patients from 10 states showed vitamin E acetate in all 29, Anne Schuchat, MD, CDC principal deputy director, reported during a call with reporters. (medscape.com)
- Vitamin E acetate was "universally" detected and no other potential toxins have been detected in the testing done so far, she said. (medscape.com)
- These findings provide direct evidence of vitamin E acetate at the primary site of injury within the lung," Schuchat added. (medscape.com)
- The lung findings are consistent with product testing that found vitamin E acetate in product samples used by EVALI patients. (medscape.com)
- Vitamin E acetate usually does not cause harm when swallowed as a vitamin supplement or applied topically to the skin, but previous research has suggested that it may interfere with normal lung function when inhaled, Schuchat said. (medscape.com)
- Schuchat emphasized that the vitamin E acetate findings do not rule out other possible compounds or ingredients that may be causing the lung injuries. (medscape.com)
- Until the relationship of vitamin E acetate and lung health is better characterized, it's important that vitamin E acetate not be added to e-cigarette, or vaping, products," Schuchat said. (medscape.com)
- Sodium Acetate Injection, USP (2 mEq/mL) is indicated as a source of sodium for addition to large volume intravenous fluids to prevent or correct hyponatremia in patients with restricted or no oral intake. (nih.gov)
- The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate. (nih.gov)
- Desmopressin acetate tablets contain either 0.1 or 0.2 mg desmopressin acetate. (nih.gov)
- Desmopressin acetate tablets contain as active substance, desmopressin acetate, a synthetic analogue of the natural hormone arginine vasopressin. (nih.gov)
- Following administration of desmopressin acetate tablets, the onset of antidiuretic effect occurs at around 1 hour, and it reaches a maximum at about 4 to 7 hours based on the measurement of increased urine osmolality. (nih.gov)
- The use of desmopressin acetate tablets in patients with an established diagnosis will result in a reduction in urinary output with an accompanying increase in urine osmolality. (nih.gov)
- No lessening of effect was observed in the 46 patients who were treated with desmopressin acetate tablets for 12 to 44 months and no serum antibodies to desmopressin were detected. (nih.gov)
- In the four long-term studies of desmopressin acetate tablets, no increases in blood pressure in 46 patients receiving desmopressin acetate tablets for periods of 12 to 44 months were reported. (nih.gov)
- In one study, the pharmacodynamic characteristics of desmopressin acetate tablets and intranasal formulation were compared during an 8-hour dosing interval at steady state. (nih.gov)
- All metallic acetates are inorganic salts containing a metal cation and the acetate anion, a univalent (-1 charge) polyatomic ion composed of two carbon atoms ionically bound to three hydrogen and two oxygen atoms (Symbol: CH3COO) for a total formula weight of 59.05. (americanelements.com)
- An enzyme catalysing the hydrolysis of a-tocopheryl acetate was characterised in chicken liver. (who.int)
- Sodium Acetate Injection, USP (2 mEq/mL) is a sterile, nonpyrogenic, concentrated solution of sodium acetate in water for injection. (nih.gov)
- Sodium Acetate, USP anhydrous is chemically designated CH 3 COONa, a hygroscopic powder very soluble in water. (nih.gov)
- Sodium Acetate Injection, USP (2 mEq/mL) is contraindicated in patients with hypernatremia or fluid retention. (nih.gov)
- Sodium Acetate Injection, USP (2 mEq/mL) must be diluted before use. (nih.gov)
- one acetate in the workplace not exceed 4 ppm over a 15 study showed an increase in tumors of the noses of rats who minute period. (cdc.gov)
- Uranyl Acetate is a moderately water soluble crystalline Uranium source that decomposes to Uranium oxide on heating. (americanelements.com)
- There are reports of an occasional change in response to the intranasal formulations of desmopressin acetate (desmopressin acetate Nasal Spray and desmopressin acetate Rhinal Tube). (nih.gov)
- Solutions containing acetate ions should be used with great care in patients with metabolic or respiratory alkalosis. (nih.gov)
- The phase III, multicenter, randomized, placebo-controlled PreCISe trial assessed glatiramer acetate (GA) effects in patients with clinically isolated syndromes (CIS) suggestive of multiple sclerosis (MS). To assess the neuroprotective effect of GA in a subset of patients in the PreCISe trial, we used proton magnetic resonance spectroscopy (MRS) to measure N-acetylaspartate (NAA), a marker of neuronal integrity, in a large central volume of brain. (nih.gov)
- A sophisticated shape, the classic cat-eye glasses are reimagined in a mix of materials, with a gold-toned metal bridge contrasting the bold black acetate frame. (refinery29.com)
- Made from black acetate, this square-framed pair is inlaid with silver-tone metal and the house's emblem at the temples. (mrporter.com)
- Rectangular black acetate frame features an 8mm chunky front that's sculpted to maximize volume and wearability. (valentino.com)
- Acetates are excellent precursors for production of ultra high purity compounds, catalysts, and nanoscale materials . (americanelements.com)
- Uranyl Nitrate and Uranyl Acetate are used in medical and analytical laboratories. (americanelements.com)
- The information below refers to products available in the United States that contain aluminum acetate . (drugs.com)
- The earrings are made with high-quality acetate and feature hypoallergenic titanium posts. (zennioptical.com)
- By now most music heads have heard the story of Warren Hill picking up the rare acetate of the Velvet Underground's lost Scepter studio sessions on a Chelsea Street for 75 cents, and how it recently turned into E-Bay mania (selling for $25,000 after an aborted first attempt that was ruined by fake high bidders). (wfmu.org)
- The frames are made from bio-acetate, a biodegradable and recyclable cellulose acetate. (mulberry.com)
- DALLAS, AMSTERDAM & SHANGHAI-(BUSINESS WIRE)- $CE -Celanese Corporation (NYSE:CE), a global chemical and specialty materials company, today announced it will raise prices of all acetate tow product grades sold globally by $ 0.40/kg or € 0.34/kg. (dutchnews.nl)