(1/91) Substance P-induced vasodilatation is mediated by the neurokinin type 1 receptor but does not contribute to basal vascular tone in man.

AIMS: Following intravenous administration of its prodrug, L-758,298, we assessed the pharmacodynamics of L-754,030, a novel and highly selective NK1 receptor antagonist, by examining systemic haemodynamics and the blood flow responses to intra-arterial substance P infusion. METHODS: Sixteen healthy male volunteers participated in a double-blind, randomised, placebo controlled crossover trial of L-758 298. Forearm blood flow was measured using venous occlusion plethysmography during intrabrachial substance P infusion (0.125-128 pmol min-1 ). In part 1, eight subjects received substance P infusions before and during placebo, 0.25 mg, 1 mg or 5 mg of L-758 298. In part 2, eight subjects received substance P infusions 24 h after placebo or 1.43 mg of L-758 298. RESULTS: L-758 298 caused dose dependent inhibition of substance P induced vasodilatation (P<0.001). Placebo adjusted differences (95% CI) in baseline forearm blood flow, mean arterial pressure and heart rate showed no relevant changes with 5 mg of L-758 298 (>1400-fold shift in substance P response): 0.00 (-0.49 to +0.49) ml 100 ml-1 min-1, 1. 0 (-3.2 to +5.2) mmHg and 1.9 (-5.9 to +9.7) beats min-1, respectively. Twenty-four hours after 1.43 mg of L-758,298, there was approximately 34-fold shift in response to substance P induced vasodilatation (P<0.008) at plasma L-754 030 concentrations of 2-3 ng ml-1. L-758 298 was generally well tolerated without serious adverse events. CONCLUSIONS: Substance P induced forearm vasodilatation is mediated by the endothelial cell NK1 receptor in man but endogenous substance P does not appear to contribute to the maintenance of peripheral vascular tone or systemic blood pressure.  (+info)

(2/91) Substance P receptor antagonist I: conversion of phosphoramidate prodrug after i.v. administration to rats and dogs.

A water-soluble phosphoramidate prodrug (L-758,298, compound I) of the potent and selective human Substance P receptor antagonist L-754, 030 (compound II) is under development as an i.v. drug for treatment of emesis, migraine, and chronic pain. Compound I undergoes hydrolysis readily to II under acidic conditions. In the studies reported herein, we investigated the stability of I in blood and hepatic subcellular fractions from rats, dogs, and humans as well as the conversion of I to II in rats and dogs after i.v. dosing. Compound I was converted to II rapidly in rat blood but was stable in dog and human blood. However, the conversion was rapid in liver microsomes prepared from dogs and humans. As expected from the results of in vitro studies, the in vivo conversion of I to II was rapid after i.v. dosing of I to rats and dogs. The relative extent of exposure of II after i.v. dosing of I was estimated by comparing the dose-adjusted area under the plasma concentration versus time curve values of II after i.v. dosing of I with those after i.v. dosing of II. In rats, the extent of exposure was estimated to be approximately 90 and approximately 100% at 1 and 8 mg/kg, respectively; in dogs, that was approximately 59% at 0.5 mg/kg. A nonproportional increase in the area under the concentration versus time curve value of II with dose was observed after i.v. administration of I in dogs from 0.5 to 32 mg/kg, suggesting that the elimination of II might have been saturated at higher doses.  (+info)

(3/91) Reduction of acetals with samarium diiodide in acetonitrile in the presence of Lewis acids.

Transformation of acetals into ethers by partial reduction using a samarium diiodide-Lewis acids-acetonitrile system is described. The reaction with aromatic acetals occurred in good yields in the presence of aluminum chloride (2 eq) whereas the corresponding aliphatic, vinylic, and alkynyl derivatives did not afford ethers under the same conditions. Beta-elimination to give an enol ether becomes predominant when aliphatic acetals that possess a hydrogen at the 2-position are treated with iodotrimethylsilane in the presence of SmI2 or SmI3.  (+info)

(4/91) Regioselective nucleophilic addition of methoxybenzene derivatives to the beta-carbon of p-benzoquinone mono O,S-acetal.

Regioselective nucleophilic addition of electron rich aromatics to the beta-position of acetal carbon of p-benzoquinone mono O,S-acetal was achieved by modifying the acetal moiety.  (+info)

(5/91) The first example of alpha-thiomagnesiums generated from dithioacetal monoxides with Grignard reagent; their properties and some synthetic applications.

Dithioacetal monoxides were synthesized from aldehydes and cyclohexanone, and reaction of the dithioacetal monoxides with Grignard reagents was investigated. The dithioacetal monoxide synthesized from alkylaldehyde and 4-chlorobenzenethiol reacted with i-PrMgCl to afford the desired alpha-thiomagnesium in high yield. The generated alpha-thiomagnesium was found to be stable at room temperature and to be useful in organic synthesis. In contrast to this, the dithioacetal monoxides derived from benzaldehyde and cyclohexanone did not give satisfactory results.  (+info)

(6/91) Quantitative analysis of fatty acid precursors in marine samples: direct conversion of wax ester alcohols and dimethylacetals to FAMEs.

To apply fatty acid analyses to the study of foraging ecology and diet determination, all compounds that may be deposited as fatty acids in a predator must be quantified in the prey. These compounds include the usual fatty acids in acyl lipids, but also the alcohols of wax esters and the vinyl ethers of plasmalogens. In routine fatty acid analysis, samples are extracted and transesterified (methylated), resulting in the formation of fatty acid methyl esters (FAMEs); however, fatty alcohols and dimethylacetals (DMAs) are also generated if wax esters or plasmalogens are present. Here, we present a new method using a modified Jones' reagent to oxidize these alcohols and DMAs to free fatty acids (FFAs). These FFAs are then easily methylated and quantitatively recombined with FAMEs from the same sample. This generates a fatty acid signature of prey that is equivalent to that which the predator has available for deposition upon digestion of that prey. This method is validated with alcohol and DMA standards. Its application to typical marine samples is also presented, demonstrating the change in effective fatty acid signature after inclusion of fatty acids derived from wax esters and plasmalogens.  (+info)

(7/91) Regioselectivity in sulfation of galactosides by sulfuric acid and dicyclohexylcarbodiimide.

Methyl alpha- and beta-D-galactopyranosides and 4-O-beta-D-galactopyranosyl-3,6-anhydro-L-galactose dimethylacetal were sulfated with sulfuric acid and dicyclohexylcarbodiimide as a condensation reagent. The sulfated sugars were isolated by ion-exchange chromatography, characterized, and assigned by methylation analyses. On the basis of the yield of each sulfated product that was isolated, sulfation on O-6 appeared to be predominant.  (+info)

(8/91) Conversion of fatty aldehyde dimethyl acetals to the corresponding alk-1-enyl methyl ethers (substituted vinyl ethers) during gas-liquid chromatography.

The behavior of palmitaldehyde and linolealdehyde and of their dimethyl acetals during gas-liquid chromatography on beta-cyclodextrin acetate (beta-CDX acetate) and ethylene glycol succinate polyester-phosphoric acid (EGSP) columns was studied. The aldehydes were well separated from their dimethyl acetals on the beta-CDX acetate column. However, on the EGSP column the retention times of palmitaldehyde and its dimethyl acetal were identical; a mixture of linolealdehyde and its dimethyl acetal gave a split peak. The aldehydes were recovered unchanged in 80-85% yield by preparative GLC from both columns, but the dimethyl acetals were quantitatively converted to the corresponding alk-1-enyl methyl ethers. The structure of these compounds was elucidated by infrared spectroscopy, mass spectrometry, and chemical means. Upon hydrolysis at low temperatures with 100% H(2)SO(4) they yielded the corresponding aldehydes, which were identified as 2,4-dinitrophenylhydrazones.  (+info)

*  Anomeric effect
... density redistribution in acetals proposed by this hypothesis is not congruent with the known experimental chemistry of acetals ...
*  2,3-Wittig rearrangement
S-acetals. Stereoselective methods employing chiral starting materials have been used to effect either asymmetric induction or ...
*  Acetal
Although many compounds contain an acetal functional group, at least two acetal compounds are called "acetal" for short: ... The two R groups can be equivalent to each other (a "symmetric acetal") or not (a "mixed acetal"), and one or both can even be ... For example, an acetal formed from formaldehyde is sometimes called a "formal" or the methylenedioxy group. The acetal formed ... Acetals are stable towards basic media. In a transacetalisation or crossacetalisation a diol reacts with an acetal or two ...
*  Dioxolane
... is a heterocyclic acetal with the chemical formula (CH2)2O2CH2. It is related to tetrahydrofuran by interchange of ... NaBArF4 can also be used for deprotection of acetal or ketal-protected carbonyl compounds. For example, deprotection of 2- ... Chang, Chih-Ching; Liao, Bei-Sih; Liu, Shiuh-Tzung (2007). "Deprotection of Acetals and Ketals in a Colloidal Suspension ... Collective Volume, 5, p. 303 Greene, Theodora W.; Wuts, Peter G. M. (1999). "Dimethyl acetals". Greene's Protective Groups in ...
*  Tetrakis(3,5-bis(trifluoromethyl)phenyl)borate
NaBArF4 can be used in deprotection of acetal or ketal-protected carbonyl compounds. For example, deprotection of 2-phenyl-1,3- ... Chang, Chih-Ching; Liao, Bei-Sih; Liu, Shiuh-Tzung (2007). "Deprotection of Acetals and Ketals in a Colloidal Suspension ... Greene, Theodora W.; Wuts, Peter G. M. (1999). "Dimethyl acetals". Greene's Protective Groups in Organic Synthesis (3rd ed.). ...
*  Guitar pick
Acetal. Acetal is a highly durable class of plastics. Delrin is DuPont's trademarked name for a type of acetal. Delrin is hard ... Matte finish acetal picks like the Clayton Acetal generate a bit more pick noise, and a more aggressive attack, but the ... The friction between a steel or nickel guitar string, and smooth, glossy acetal is very low. Glossy delrin picks literally ...
*  Polyoxymethylene
"Acetal". Machine Design. November 15, 2002. Retrieved August 2015. Check date values in: ,access-date= (help) "Acetal (POM) ... Solvent welding is typically unsuccessful on acetal polymers, due to the excellent solvent resistance of acetal.[citation ... "How to Maximise the Property Advantages of DuPont Delrin Acetal Homopolymer over Acetal Copolymer" (PDF). DuPont. 2013. ... 473-. ISBN 978-1-4200-9384-1. "Acetal Products Comparison: Acetal vs. Delrin" (PDF). Lion Engineering Plastics. Retrieved 2016- ...
*  Ethylene glycol
"Ethylene glycol acetal". The Organic Synthesis Archive. synarchive.com. Theodora W. Greene; Peter G. M. Wuts (1999). Protective ...
*  Thioacetal
... s are the sulfur analogues of acetals. There are two classes: monothioacetals and dithioacetals. Monothioacetals are ...
*  Tetrahedral carbonyl addition compound
... called acetals. The whole mechanism of acetal formation from hemiacetal is drawn below. Acetals, as already pointed out, are ... Acetals are stable under basic conditions, so they can be used to protect ketones from a base. Acetal group is hydrolyzed under ... Hemiacetals and acetals are essentially tetrahedral intermediates. They form when nucleophiles add to a carbonyl group, but ... Formation of an acyclic acetal involves a decrease in entropy because two molecules are consumed for every one produced. In ...
*  Fluoroboric acid
Acetonitrile solutions cleave acetals and some ethers. Many reactive cations have been obtained using fluoroboric acid, e.g. ...
*  N-Bromosuccinimide
Binkley, R. W.; Goewey, G. S.; Johnston, J. (1984). "Regioselective ring opening of selected benzylidene acetals. A ...
*  Permanganate
Lloyd Evans, Henry Hass, and E. F. Schroeder (1931). "dl-glyceraldehyde ethyl acetal". Organic Syntheses. 2: 307. CS1 maint: ...
*  Acetonide
Diol Protecting Groups-Acetals-Isopropylidene Acetals". Protecting Groups. Foundations of Organic Chemistry Series. Thieme. p. ...
*  Trimethylenemethane cycloaddition
Acetal 1 has been used in this context, and provides cyclopentanes with the acetal functionality exo to the newly formed ring ... When heated, cyclopropene acetals rearrange to vinylcarbenes, which can serve as the three-atom component in cycloadditions ... Orthoester products are generally favored over ketene acetals. (13) The high stereospecificity and stereoselectivity inherent ...
*  Paraformaldehyde
... is a poly-acetal. Paraformaldehyde forms slowly in aqueous formaldehyde solutions as a white precipitate, ...
*  3,9-Diethylidene-2,4,8,10-tetraoxaspiro(5.5)undecane
"Preparation of ketene acetals by rearrangement of allyl and substituted allyl acetals" US 6863782, P.W. Newsome et al., "Method ... is a bicyclic ketene acetal derived from the isomeric allyl acetal 3,9-divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane (DVTOSU). As ... The diketene acetal 3,9-diethylidene-2,4,8,10-tetraoxaspiro[5.5]undecane, DETOSU, is a reactive bifunctional monomer that forms ... of preparing di(ketene acetals)" Crivello, J. V.; Malik, R.; Lai, Y.-L. (1996). "Ketene acetal monomers: Synthesis and ...
*  Hemiacetal
These do not form as readily as hemiacetals and acetals. To increase yields of ketals or acetals, water formed during the ... Acetals are products of substitution reactions catalyzed by acid. The presence of acid improves the leaving capacity of the ... hemiacetal + alcohol (excess) + acid (catalyst) ↔ acetal + water An aldehyde dissolved in water exists in equilibrium with low ... in contrast to acetals or ketals, which are formed when a second alkoxy group has been added to the structure. The general ...
*  Ytterbium(III) chloride
doi:10.1016/S0040-4039(02)00935-8. Luche, Jean-Louis; Gemal, André Luis (1978). "Efficient synthesis of acetals catalysed by ... chloride is a powerful catalyst for the formation of acetals using trimethyl orthoformate. In comparison with cerium(III) ...
*  Aluminium hydride
... can be used in the reduction of acetals to half protected diols. Aluminium hydride can also be used in ... "A Facile Cleavage of Benzylidene Acetals with Diisobutylaluminum Hydride" (pdf). Chemistry Letters. 12 (10): 1593-1596. doi: ...
*  Ocinaplon
"A-Amino Acetals: 2,2-Diethoxy-2-(4-Pyridyl)Ethylamine". Organic Syntheses. 64: 19. 1986. doi:10.15227/orgsyn.064.0019. U.S. ... Condensation of 4-Acetylpyridine with N,N-Dimethylformamide dimethyl acetal (DMFDMA) gives the "enamide" (3). This is then ...
*  Curtin-Hammett principle
Stannylene acetals have been used to efficiently achieve this transformation. The asymmetric diol is first treated with a tin ... Initially, the less stable isomer predominates, as it is formed more quickly from the stannyl acetal. However, allowing the two ... reagent to produce the dibutylstannylene acetal. This compound is then treated with one equivalent of acyl chloride to produce ...
*  2-Butoxyethanol
Bonner, Trevor (1981). "Opening of cyclic acetals by trichloro-, dichloro-, and tribromo-borane". Journal of the Chemical ...
*  Rubottom oxidation
... silyl ketene acetals and bis(silyl acetals) can be oxidized to their α-hydroxy ester or carboxylic acid derivatives using lead( ... silyl ketene acetals, and bis(silyl acetals), derived from carboxylic acids, in good yields at or below room temperature. The ... An inherent problem with mCPBA is its inability to oxidize silyl ketene acetals. In order to synthesize α-hydroxy esters, ... This methodology also gave high yields and enentioselectivities for silyl enol ethers as well as silyl ketene acetals derived ...
*  Dispersin B
Chibba A, Dasgupta S, Yakandawala N, Madhyastha S, Nitz M (2011). "Chromogenic Carbamate and Acetal Substrates for ...
Acetals/Ketals/Ortho Esters - Oxygen Compounds | Sigma-Aldrich  Acetals/Ketals/Ortho Esters - Oxygen Compounds | Sigma-Aldrich
Acetals are stable under basic conditions, can be hydrolyzed back to the carbonyl compound, can serve as a carbonyl protecting ... Ketals are equivalent to acetals and contain a carbon bonded to two O-R (R = alkyl group). Ortho esters contain three alkoxy ... Cyclic acetals are utilized as biomaterials in tissue engineering. Poly(ortho esters) exhibit synthetic versatility and ... Acetals, usually derived from aldehydes, are two single-bonded oxygen atoms attached to the same carbon atom, with the ...
more infohttps://www.sigmaaldrich.com/chemistry/chemistry-products.html?TablePage=16257316
Acetal Resins Manufacturers, Suppliers & Exporters in India  Acetal Resins Manufacturers, Suppliers & Exporters in India
Contact to Acetal Resins Exporters in India, Acetal Resins Wholesalers, Acetal Resins Distributors and Traders from India. ... Search Indian Acetal Resins Manufacturers and Suppliers Details - ... Deals in Acid / Alkyl Chlorides, dental waxes, Chlorinated Rubber: Halorub, calcium carbonate flakes, Acetal Resins, ...
more infohttp://www.indianyellowpages.com/india/manufacturers/a/acetal-resins.htm
Acetaldehyde dimethyl acetal, 90% manufacturing companies  Acetaldehyde dimethyl acetal, 90% manufacturing companies
Acetaldehyde dimethyl acetal, 90%. IUPAC Name. 1,1-Dimethoxyethane Or Dimethyl acetal F.W. 90.1 bp : 64 C Fp : -17 C(1 F), ... Acetaldehyde dimethyl acetal, 90% manufacturers and suppliers. Search. Search by Drug Name, Company, CAS, Chem formula, IUPAC ... We are sorry, there are no companies found in " Acetaldehyde dimethyl acetal, 90%" Listing your company for Acetaldehyde ... dimethyl acetal, 90% allows buyers to find your information through our directory pages which appear in the top positions when ...
more infohttp://www.poulvet.com/bulk_drugs/product_companies_india.php?sclid=6267&prefix=Q
Acetaldehyde dimethyl acetal  CAS: 105-57-7  Acetaldehyde dimethyl acetal CAS: 105-57-7
Manufacturer and Suppliers of Acetaldehyde dimethyl acetal CAS: 105-57-7 from Germany, China, United States of America and ...
more infohttps://exportpages.com/cas/105-57-7/acetaldehyde-dimethyl-acetal.htm
China Acetal Copolymer (POM 90/120/270) - China Acetal Copolymer, Pom  China Acetal Copolymer (POM 90/120/270) - China Acetal Copolymer, Pom
Find details about China Acetal Copolymer, Pom from Acetal Copolymer (POM 90/120/270) - Jinan ZZ International Trade Co., Ltd. ... Acetal Copolymer, Pom, Acetal Copolymer 90 manufacturer / supplier in China, offering Acetal Copolymer (POM 90/120/270), China ...
more infohttp://jinanzz.en.made-in-china.com/product/heNmpGoOEyRk/China-Acetal-Copolymer-POM-90-120-270-.html
ChemIDplus - 125229-74-5 - Acetic acid ethenyl ester, homopolymer, hydrolyzed, cyclic acetal with 4-(2-(4-formylphenyl)ethenyl)...  ChemIDplus - 125229-74-5 - Acetic acid ethenyl ester, homopolymer, hydrolyzed, cyclic acetal with 4-(2-(4-formylphenyl)ethenyl)...
... cyclic acetal with 4-(2-(4-formylphenyl)ethenyl)-1-methylpyridinium, Me sulfate - Searchable synonyms, formulas, resource links ... Substance Name: Acetic acid ethenyl ester, homopolymer, hydrolyzed, cyclic acetal with 4-(2-(4-formylphenyl)ethenyl)-1- ... Acetic acid ethenyl ester, homopolymer, hydrolyzed, cyclic acetal with 4-(2-(4-formylphenyl)ethenyl)-1-methylpyridinium Me ... Acetic acid ethenyl ester, homopolymer, hydrolyzed, cyclic acetal with 4-(2-(4-formylphenyl)ethenyl)-1-methylpyridinium, Me ...
more infohttps://chem.nlm.nih.gov/chemidplus/rn/125229-74-5
Acetal - Wikipedia  Acetal - Wikipedia
Although many compounds contain an acetal functional group, at least two acetal compounds are called "acetal" for short: ... The two R groups can be equivalent to each other (a "symmetric acetal") or not (a "mixed acetal"), and one or both can even be ... For example, an acetal formed from formaldehyde is sometimes called a "formal" or the methylenedioxy group. The acetal formed ... Acetals are stable towards basic media. In a transacetalisation or crossacetalisation a diol reacts with an acetal or two ...
more infohttps://en.wikipedia.org/wiki/Acetal
Dimethyl Acetals  Dimethyl Acetals
... T. W. Green, P. G. M. Wuts,. Protective Groups in Organic Synthesis,. Wiley-Interscience, New York, 1999, 297 ... A convenient deprotection of acyclic and cyclic O,O-acetals and O,O-ketals is achieved in excellent yields within minutes under ... Acetals offer stability against all types of nucleophiles and bases and most oxidants, so long as the conditions do not lead to ... Dimethyl acetals can be prepared from carbonyl compounds with excess methanol catalyzed by a Br nsted (i.e. protic) acid or ...
more infohttps://www.organic-chemistry.org/protectivegroups/carbonyl/dimethylacetals.htm
Acetals
    -
    Carbohydrate Chemistry
    (RSC Publishing)  Acetals - Carbohydrate Chemistry (RSC Publishing)
You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page ...
more infohttps://pubs.rsc.org/en/content/chapter/cr9780854042289-00092/978-0-85404-228-9
Riesling acetal  Riesling acetal
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
more infohttps://webbook.nist.gov/cgi/cbook.cgi?ID=R617273&Mask=2000
Hydroxy amide acetals in coatings - Drysdale, Neville Everton  Hydroxy amide acetals in coatings - Drysdale, Neville Everton
The present invention relates to the use of hydroxy functionalized amide acetals as reactive components with crosslinking ... Alternately, the amide acetal may be functionalized, for example, via reaction of (mono)hydroxy amide acetal with isocyanate to ... It is to be understood that as the water contacts the amide acetal groups present in the composition, the amide acetal groups ... a hydroxy amide acetal of the formula wherein R42-R49 independently represent a hydrogen, C1-C20 alkyl, C1-C20 alkenyl, C1-C20 ...
more infohttp://www.freepatentsonline.com/y2006/0069205.html
Polyvinyl acetal | Define Polyvinyl acetal at Dictionary.com  Polyvinyl acetal | Define Polyvinyl acetal at Dictionary.com
Polyvinyl acetal definition, any of the class of thermoplastic resins derived by the condensation of an aldehyde with polyvinyl ... Origin of polyvinyl acetal. First recorded in 1930-35. Dictionary.com Unabridged Based on the Random House Unabridged ...
more infohttps://www.dictionary.com/browse/polyvinyl-acetal
Polyvinyl acetal | Define Polyvinyl acetal at Dictionary.com  Polyvinyl acetal | Define Polyvinyl acetal at Dictionary.com
Polyvinyl acetal definition, any of the class of thermoplastic resins derived by the condensation of an aldehyde with polyvinyl ...
more infohttp://www.dictionary.com/browse/polyvinyl-acetal?qsrc=2446
ACETAL (POM)  ACETAL (POM)
You are here: Home / Products / RTP Company Specialty Compounds / ACETAL (POM). ACETAL (POM). Advantages. *Resistance to creep ... Acetals are rigid, creep resistant and strong. They possess low coefficients of friction. They remain stable in high ... A 40% glass reinforced acetal has a flexural modulus of 1.6 psi x 10E-6 (11024 MPa) and 330 degrees F (166 degrees C) heat ...
more infohttps://www.rtpcompany.com/products/product-guide/acetal-pom/
Transition States for Hydrolysis of Acetals, Ketals, Glycosides, and Glycosylamines | SpringerLink  Transition States for Hydrolysis of Acetals, Ketals, Glycosides, and Glycosylamines | SpringerLink
E. Anderson and T. H. Fife, Carboxy-group participation in acetal hydrolysis. The hydrolysis of benzaldehyde disalicyl acetal, ... J. M. O'Gorman and H. J. Lucas, Hydrolysis of the acetal of D(+)-2-octanol, J. Am. Chem. Soc 72, 5489-5490 (1950).CrossRef ... The hydrolysis of substituted benzaldehyde di-tert-butyl acetals, J. Am. Chem. Soc 93, 1701-1704 (1971).CrossRefGoogle Scholar ... T. H. Fife, General acid catalysis of acetal, ketal, and ortho ester hydrolysis, Acc. Chem. Res 5, 264-272 (1972).CrossRef ...
more infohttps://link.springer.com/chapter/10.1007/978-1-4684-9978-0_11
Acrolein dimethyl acetal 98% | Sigma-Aldrich  Acrolein dimethyl acetal 98% | Sigma-Aldrich
Acrolein dimethyl acetal for your research needs. Find product specific information including CAS, MSDS, protocols and ... Acrolein dimethyl acetal was used in the facile one step synthesis of 4-hydroxy-2E-nonenal and its dimethyl acetal via a cross- ... Acetals/Ketals/Ortho Esters, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds ... Acrolein dimethyl acetal undergoes cationic α-diimine palladium chelate catalyzed copolymerization with ethene to yield ...
more infohttps://www.sigmaaldrich.com/catalog/product/aldrich/190543?lang=en®ion=US
Patent US4358603 - Acetal stabilized prostaglandin compositions - Google Patents  Patent US4358603 - Acetal stabilized prostaglandin compositions - Google Patents
... water-miscible alcohol solutions is prevented by adding a stabilizing amount of a pharmaceutically acceptable acetal. ... It is variously known as acetaldehyde diethyl acetal, acetaldehyde diethyl acetal or simply, acetal. Acetaldehyde diethyl ... and said acetal is acetaldehyde diethyl acetal or benzaldehyde diethyl acetal. ... and said acetal is acetaldehyde diethyl acetal or benzaldehyde diethyl acetal. ...
more infohttp://www.google.com/patents/US4358603?dq=6188988
АЦЕТАЛИ (acetals): Topics by WorldWideScience.org  АЦЕТАЛИ (acetals): Topics by WorldWideScience.org
Reaction of acetals with aliphatic nitro compounds - 2. Effect of structure of diethyl acetals of benzaldehydes on C- and O- ... Chemistry of acetals - Communication 1. general method for the synthesis of bis [diethyl acetals] of β-dicarbonyl compounds ... Chiral Silyl Ketene Acetals from Thioesters: Reaction with Acetals and Peroxyacetals to form 3-Alkoxy- and 3-Peroxyalkanoates ... Chemistry of acetals - 7. Polarographic investigation of some hydrolysis products of tetraethyl acetals of malonic and β- ...
more infohttps://worldwidescience.org/topicpages/multi/RU/a/acetals.html
SPECTRUM Benzaldehyde Diethyl Acetal,25g - 26ZC34|B1893-25G - Grainger  SPECTRUM Benzaldehyde Diethyl Acetal,25g - 26ZC34|B1893-25G - Grainger
Looking for SPECTRUM Benzaldehyde Diethyl Acetal,25g (26ZC34)? Grainger's got your back. Price:$148.00. Easy ordering & ...
more infohttps://www.grainger.com/product/SPECTRUM-Benzaldehyde-Diethyl-Acetal-26ZC34
EP0019999A1 - Acetals and their preparation 
        - Google Patents  EP0019999A1 - Acetals and their preparation - Google Patents
The 'clean' acetals are useful emulsifying agents and their esters and polyalkoxy substituents are useful dispersants and ... acetals of long chain fatty aliphatic aldehydes and polyols containing four or more hydroxyl groups which produces the acetals ... acetal, by reaction with a lower alkanol, followed by an acetal exchange reaction with the polyol under the above acetal ... Use of acetals US5575944A (en) * 1992-08-11. 1996-11-19. Kao Corporation. Acetal-containing working fluid composition for ...
more infohttps://patents.google.com/patent/EP0019999A1/en
  • Acetals, usually derived from aldehydes, are two single-bonded oxygen atoms attached to the same carbon atom, with the hemiacetal being an alcohol and ether attached to the same carbon atom. (sigmaaldrich.com)
  • Acetals are stable under basic conditions, can be hydrolyzed back to the carbonyl compound, can serve as a carbonyl protecting group, and are functional groups in glycosidic bonds. (sigmaaldrich.com)
  • This convenient, mild, chemoselective method allows acetalization of an aldehyde in the presence of ketone, unsymmetrical acetal formation, and tolerates acid-sensitive protecting groups. (organic-chemistry.org)
  • Acetals of diaryl ketones with nitro, halo and methoxy substituents are easily prepared in high yield by treatment with an alcohol and the corresponding trialkyl orthoformate in the presence of a catalytic amount of trifluoromethanesulfonic acid. (organic-chemistry.org)
  • hemiacetal + alcohol (excess) + acid (catalyst) ↔ acetal + water An aldehyde dissolved in water exists in equilibrium with low concentrations of its hydrate, R-CH(OH)2. (wikipedia.org)
  • Acetals are products of substitution reactions catalyzed by acid. (wikipedia.org)
  • US 5939453, J. Heller, S.Y. Ng, "PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers" US 4532335, R.F. Helwing, "Preparation of ketene acetals by rearrangement of allyl and substituted allyl acetals" US 6863782, P.W. Newsome et al. (wikipedia.org)
  • Method of preparing di(ketene acetals)" Crivello, J. V. (wikipedia.org)
  • Still more particularly, it relates to antiperspirant sticks containing an acidic antiperspirant-active compound in the presence of dibenzyl monosorbitol acetal (DBMSA) and a novel solubilizing agent therefor and to a method for producing said sticks at lower temperatures. (google.es)
  • Translucent gel sticks with dibenzyl monosorbitol acetal have been made containing acidic antiperspirant-active salts but with high temperature processing. (google.es)
  • Antiperspirant sticks containing dibenzyl monosorbitol acetal and acidic antiperspirant-active salts are disclosed by Roehl, U.S. Pat. (google.es)
  • Acetals, usually derived from aldehydes, are two single-bonded oxygen atoms attached to the same carbon atom, with the hemiacetal being an alcohol and ether attached to the same carbon atom. (sigmaaldrich.com)
  • Dimethoxymethane, a solvent, a.k.a. methylal, a.k.a. formal [ambiguous] Dioxolane Metaldehyde Paraldehyde 1,3,5-Trioxane Most glycosidic bonds in carbohydrates and other polysaccharides are acetal linkages.Cellulose is a ubiquitous example of a polyacetal. (wikipedia.org)
  • A mild and efficient method enables the formation of methylene acetals from 1,2- and 1,3-diols using methoxymethylphenylsulfide, 1,3-dibromo-5,5-dimethylhydantoin (DBDMH), and dibutylhydroxytoluene (BHT). (organic-chemistry.org)
  • The use of BHT suppresses side reactions and enables high-yielding formation of methylene acetals of various diols, including carbohydrate-type substrates. (organic-chemistry.org)
  • Enantiomerically pure acetals derived from C 2 -symmetric diols have been examined as ligands for asymmetric catalysis. (bath.ac.uk)
  • As a bifunctional monomer, DETOSU is an important building block for polyorthoesters formed by the addition of diols to the activated double bond of the diketene acetal. (wikipedia.org)
  • Suppliers of acetal say the inherent non-stick property of the resin no longer prevents good adhesion when overmolding with SEBS thermoplastic elastomers. (thefreedictionary.com)
  • A Pd-catalyzed asymmetric intermolecular hydroalkoxylation of allenes with phenol as a pronucleophile gives acyclic O,O -acetals in high yields with very good enantiomeric excesses. (organic-chemistry.org)
  • The present invention relates to the use of hydroxy functionalized amide acetals as reactive components with crosslinking agents to give new coatings compositions. (freepatentsonline.com)
  • Cross-linked amide acetal based coating compositions dry and cure rapidly without the potential problems created by VOC emissions. (freepatentsonline.com)
  • Co-owned and co-pending U.S. Patent Publication 2005-007461 describes polymeric compositions containing amide acetal groups, which are crosslinked by hydrolyzing the amide acetal groups, and subsequently reacting the hydroxyl groups and/or the amine functions that are formed to crosslink the composition. (freepatentsonline.com)
  • Polyoxymethylene (POM), also known as acetal, polyacetal, and polyformaldehyde, is an engineering thermoplastic used in precision parts requiring high stiffness, low friction, and excellent dimensional stability. (wikipedia.org)
  • Treatment of symmetrical O,O -acetals with TESOTf and 2,4,6-collidine formed weakly electrophilic collidinium salts. (organic-chemistry.org)
  • Formation of an acetal occurs when the hydroxyl group of a hemiacetal becomes protonated and is lost as water. (wikipedia.org)
  • The hydroxyl group in 4 is protonated leading to the oxonium ion 6 which accepts a second alcohol group to 7 with a final deprotonation to the acetal 8. (wikipedia.org)
  • Degradation of prostaglandins in anhydrous or aqueous pharmaceutically acceptable, water-miscible alcohol solutions is prevented by adding a stabilizing amount of a pharmaceutically acceptable acetal. (google.com)
  • 1. A stable prostaglandin composition comprising a prostaglandin dissolved in an anhydrous or aqueous pharmaceutically acceptable, water-miscible alcohol solution containing a stabilizing amount of a pharmaceutically acceptable acetal having the general formula R 1 CH(OR 2 ) 2 wherein R 1 is an alkyl radical of 1 to 4 carbon atoms or phenyl and R 2 is an alkyl radical of 1 to 4 carbon atoms. (google.com)
  • 3. A process for forming a coating composition comprising hydroxy amide acetals of claim 1, said process comprising reacting a hydroxy amide acetal with a crosslinking moiety. (freepatentsonline.com)
  • Co-owned and co-pending U.S. Patent Application 60/615,360 describes the sythesis of these hydroxy-functionalized amide acetals, and is hereby incorporated by reference in its entirety. (freepatentsonline.com)
  • Hydroxy-functionalized amide acetals find use in cross-linkable coatings. (freepatentsonline.com)
  • Application April 21,1944, Serial No. 532,213 i My invention relates to new and useful acetals of nitro alcohols, and the process of producing the same. (google.com)
  • Loss of the proton from the attached alcohol gives the acetal. (wikipedia.org)
  • The formation of acetals reduces the total number of molecules present and therefore is not favourable with regards to entropy, unless one uses a diol rather than two discrete alcohol molecules. (wikipedia.org)
  • The compound is not normally encountered in the anhydrous form, but rather as the hydrate (acetal), ClCH2CH(OH)2. (wikipedia.org)
  • The two R groups can be equivalent to each other (a "symmetric acetal") or not (a "mixed acetal"), and one or both can even be hydrogen atoms rather than organic fragments. (wikipedia.org)