Acebutolol
Practolol
Propranolol
Dihydralazine
Adrenergic beta-Antagonists
Citrus paradisi
Agrochemicals
Dictionaries as Topic
Biopharmaceutics
Pharmaceutical Preparations
Bradycardia
Atrioventricular Block
Pharmacists
Heart Block
Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
Pulmonary Disease, Chronic Obstructive
Raynaud Disease
Anaphylaxis
Renal Insufficiency
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
Allergens
Protective Devices
Hypertension
Pressure
Heart Failure
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Drugs, Generic
Ventricular Premature Complexes
A type of cardiac arrhythmia with premature contractions of the HEART VENTRICLES. It is characterized by the premature QRS complex on ECG that is of abnormal shape and great duration (generally >129 msec). It is the most common form of all cardiac arrhythmias. Premature ventricular complexes have no clinical significance except in concurrence with heart diseases.
Arrhythmias, Cardiac
Spiramycin
Isoproterenol
Cardiac Output
Encyclopedias as Topic
MedlinePlus
Consumer Health Information
Social Media
Aristolochia
A plant genus of the family ARISTOLOCHIACEAE. Species of this genus have been used in traditional medicine but they contain aristolochic acid which is associated with nephropathy. These are sometimes called 'snakeroot' but that name is also used with a number of other plants such as POLYGALA; SANICULA; ASARUM; ARISTOLOCHIA; AGERATINA; and others.
Caffeine
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Alcohol Drinking
Angina Pectoris
Treatment Outcome
Asthma
beta(1)-adrenergic antagonists improve sleep and behavioural disturbances in a circadian disorder, Smith-Magenis syndrome. (1/69)
Smith-Magenis syndrome (SMS) is a clinically recognisable contiguous gene syndrome ascribed to interstitial deletions of chromosome 17p11.2. Patients have a phase shift of their circadian rhythm of melatonin with a paradoxical diurnal secretion of the hormone. Serum melatonin levels and day-night behaviour were studied in nine SMS children (aged 4 to 17 years) given acebutolol, a selective beta(1)-adrenergic antagonist (10 mg/kg early in the morning). Cardiac examination, serum melatonin, motor activity recordings, and sleep diaries were monitored before and after drug administration. The present study shows that a single morning dose of acebutolol suppressed the inappropriate secretion of melatonin in SMS. A significant improvement of inappropriate behaviour with increased concentration, delayed sleep onset, increased hours of sleep, and delayed waking were also noted. These results suggest that beta(1)-adrenergic antagonists help to manage hyperactivity, enhance cognitive performance, and reduce sleep disorders in SMS. (+info)Streptococcus pneumoniae PstS production is phosphate responsive and enhanced during growth in the murine peritoneal cavity. (2/69)
Differential display-PCR (DDPCR) was used to identify a Streptococcus pneumoniae gene with enhanced transcription during growth in the murine peritoneal cavity. Northern dot blot analysis and comparative densitometry confirmed a 1.8-fold increase in expression of the encoded sequence following murine peritoneal culture (MPC) versus laboratory culture or control culture (CC). Sequencing and basic local alignment search tool analysis identified the DDPCR fragment as pstS, the phosphate-binding protein of a high-affinity phosphate uptake system. PCR amplification of the complete pstS gene followed by restriction analysis and sequencing suggests a high level of conservation between strains and serotypes. Quantitative immunodot blotting using antiserum to recombinant PstS (rPstS) demonstrated an approximately twofold increase in PstS production during MPC from that during CCs, a finding consistent with the low levels of phosphate observed in the peritoneum. Moreover, immunodot blot and Northern analysis demonstrated phosphate-dependent production of PstS in six of seven strains examined. These results identify pstS expression as responsive to the MPC environment and extracellular phosphate concentrations. Presently, it remains unclear if phosphate concentrations in vivo contribute to the regulation of pstS. Finally, polyclonal antiserum to rPstS did not inhibit growth of the pneumococcus in vitro, suggesting that antibodies do not block phosphate uptake; moreover, vaccination of mice with rPstS did not protect against intraperitoneal challenge as assessed by the 50% lethal dose. (+info)Evidence towards the role of arylamine N-acetyltransferase in Mycobacterium smegmatis and development of a specific antiserum against the homologous enzyme of Mycobacterium tuberculosis. (3/69)
Arylamine N-acetyltransferase (NAT) in humans inactivates the anti-tubercular drug isoniazid (INH). Homologues of human NAT are present in Mycobacterium tuberculosis and Mycobacterium smegmatis, where they can acetylate, and hence inactivate, INH. The in vivo role of mycobacterial NAT is not known but heterologous expression of the M. tuberculosis gene increases the INH resistance. The 0.85 kb nat gene is part of a gene cluster in M. smegmatis. The gene is transcribed as a large, 7.5 kb mRNA as demonstrated by Northern analysis. A nat knockout strain of M. smegmatis was generated by targeted disruption. The new strain was confirmed to be devoid of NAT activity. The growth of the knockout strain is considerably delayed compared with the wild-type, due to an extended lag phase. The knockout mutant has an increased sensitivity to INH as would be predicted. The NATs from M. smegmatis and M. tuberculosis have a high degree of homology, except in the region of the C terminus. A specific polyclonal antiserum raised against recombinant NAT protein from M. tuberculosis is described that recognizes a stretch of about twenty residues within the C terminus of M. tuberculosis NAT. This highly specific antiserum will enable comparison of nat expression between isolates of M. tuberculosis. (+info)Plasma levels and beta-adrenoceptor blockade with acebutolol, practolol and propranolol in man. (4/69)
1 The degree of beta-adrenoceptor blockade of isoprenaline-induced tachycardia has been determined in three healthy volunteers after the administration of single oral doses of acebutolol, practolol or propranolol. 2 Plasma levels of these drugs were determined either colorimetrically (acebutolol and practolol) or fluorimetrically (propranolol). The colorimetric assay of acebutolol in plasma is fully described but the other drugs were assayed by published methods. 3 The degree of beta-adrenoceptor blockade and the plasma level for acebutolol and practolol were well correlated, whereas in the case of propranolol correlation was poor, due in part to the presence in plasma of active metabolites not detected by the fluorimetric assay. The plasma levels of practolol and propranolol are in agreement with those previously reported. 4 The maximum cardiac beta-adrenoceptor blockade achieved in this study with the respective single oral doses of acebutolol (300 mg), practolol (400 mg) or propranolol (40 mg) were similar in each of the three subjects. Therefore the beta-adrenoceptor blocking potencies of these drugs against isoprenaline-induced tachycardia are inversely related to these doses; indicating that propranolol is 7-8 times more potent than acebutolol and the latter slightly more potent than practolol. (+info)Comparison of the actions of acebutolol, practolol and propranolol on calcium transport by heart microsomes and mitochondria. (5/69)
1 The effects of acebutolol, practolol and propranolol (0,5-3 mM) on calcium uptake, calcium binding and ATPase activities of the rabbit and rat heart microsomal and mitochondrial fractions were investigated. 2 Dose-response and time course experiments revealed that propranolol greatly inhibited microsomal and mitochondrial calcium uptake whereas both acebutolol and practolol showed slight depressant effects. 3 The ATPase activities of microsomal and mitochondrial fractions were decreased by acebutolol, practolol and propranolol; however, the latter agent was more effective than the other two. 4 The inhibitory effects of acebutolol, practolol and propranolol on mitochondria and microsomes were not antagonized by adrenaline. 5 Propranolol decreased calcium binding by the microsomal fraction only, whereas acebutolol and practolol had no effect on microsomal or mitochondrial calcium binding. 6 The sensitivity of the rabbit heart subcellular fractions to the beta-adrenoceptor blocking drugs was similar to that of the rat heart; however, the calcium uptake and ATPase activities of microsomes were more sensitive to propranolol than mitochondria in both species. 7 Perfusion of rat hearts with 0.2-1 mM propranolol decreased contractile force, and microsomal and mitochondrial fractions obtained from these hearts accummulated less calcium in comparison to the control. On the other hand, acebutolol and practolol (0.2-1nM) had no appreciable effects on contractile force or subcellular fractions under similar conditions. 8 The negative inotropic effect of propranolol may partly be due to its inhibitory actions on calcium transport by subcellular organelles of the myocardium; the depressant action of propranolol on calcium transport is unlikely to be due to its beta-adrenoceptor blocking property. (+info)Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo. (6/69)
In the sea urchin embryo, the oral-aboral axis is specified after fertilization by mechanisms that are largely unknown. We report that early sea urchin embryos express Nodal and Antivin in the presumptive oral ectoderm and demonstrate that these genes control formation of the oral-aboral axis. Overexpression of nodal converted the whole ectoderm into oral ectoderm and induced ectopic expression of the orally expressed genes goosecoid, brachyury, BMP2/4, and antivin. Conversely, when the function of Nodal was blocked, by injection of an antisense Morpholino oligonucleotide or by injection of antivin mRNA, neither the oral nor the aboral ectoderm were specified. Injection of nodal mRNA into Nodal-deficient embryos induced an oral-aboral axis in a largely non-cell-autonomous manner. These observations suggest that the mechanisms responsible for patterning the oral-aboral axis of the sea urchin embryo may share similarities with mechanisms that pattern the dorsoventral axis of other deuterostomes. (+info)Effects of grapefruit juice on the pharmacokinetics of acebutolol. (7/69)
AIMS: We aimed to investigate effects of grapefruit juice on acebutolol pharmacokinetics. METHODS: In a randomized cross-over study, 10 healthy subjects ingested 200 mL grapefruit juice or water three times daily for 3 days and twice on day 4. On day 3, each subject ingested 400 mg acebutolol with grapefruit juice or water. The concentrations of acebutolol and its metabolite diacetolol were measured in plasma and urine up to 33 h. RESULTS: Grapefruit juice decreased the peak plasma concentration (Cmax) of acebutolol by 19% from 872 +/- 207 ng mL(-1) to 706 +/- 140 ng mL(-1) (95% CI on the difference -306, -26.4; P < 0.05), and the area under the concentration time curve (AUC(0-33 h)) by 7%, from 4498 +/- 939 ng mL(-1) h to 4182 +/- 915 ng mL(-1) h (95% CI -609, -23.0; P < 0.05). The half-life (t1/2) of acebutolol prolonged from 4.0 to 5.1 h (P < 0.05). The time to peak concentration and the amount of acebutolol excreted into urine (Ae) were unchanged. The Cmax, AUC(0-33 h), and Ae of diacetolol were decreased by 24% (P < 0.05), 18% (P < 0.05), and 20% (P < 0.01), respectively, by grapefruit juice. CONCLUSION: Grapefruit juice caused a small decrease in the plasma concentrations of acebutolol and diacetolol by interfering with gastrointestinal absorption. The interaction between the grapefruit juice and acebutolol is unlikely to be of clinical significance in most of the patients. (+info)Transport of acebutolol through rabbit corneal epithelium. (8/69)
The purpose of this study is to characterize transport of acebutolol through the corneal epithelium. Cultured normal rabbit corneal epithelial cells (RCEC) were used to investigate the drug transport. Primary RCEC were seeded on a filter membrane of Transwell-COL insert coated with fibronectin and were grown in Dulbecco's modified Eagle's medium/nutrient mixture F-12 with various supplements. Measurements of acebutolol permeability through RCEC layer were carried out to assess transcellular permeability coefficient (P(transcell)) in the absence or presence of inhibitors. Paracellular permeability coefficient (P(paracell)) was calculated by permeability coefficient of hydrophilic drugs (P(cell)). The transcellular permeability of acebutolol from apical side to basal side (A-to-B) showed concentration-dependency. The acebutolol flux in the A-to-B direction was smaller than that of opposite direction. Sodium azide, verapamil, and cyclosporin A enhanced the transcellular permeability of acebutolol in the A-to-B direction. Acebutolol permeability through an excised rabbit cornea was also increased by verapamil. Thus, it was suggested that acebutolol was actively secreted via P-glycoprotein in a corneal epithelium. (+info)
DailyMed - ACEBUTOLOL HYDROCHLORIDE capsule
DailyMed - ACEBUTOLOL HYDROCHLORIDE - acebutolol hydrochloride capsule
Acebutolol, a Cardioselective Beta Blocker, Promotes Glucose Uptake in Diabetic Model Cells by Inhibiting JNK-JIP1 Interaction
acebutolol - WellSpan Health Library
Sectral (acebutolol)
Acebutolol: Side Effects, Dosage, Uses and More
Acebutolol - A Drug A Day
Acebutolol by Pro Doc - PharmaChoice
Acebutolol Drug Information, Indications & Other Medicaments on Catalog.md
Acebutolol Interaction with Food, Herbs, Alcohol and Caffeine
Acebutolol Hydrochloride - patient information, description, dosage and directions.
Sectral - definition of Sectral by The Free Dictionary
Efficacy and Safety of Propranolol Versus Acebutolol on the Proliferative Phase of Infantile Hemangioma
acebutolol Information - Drugs and Treatments - MedHelp
Acebutolol Dosage
Acebutolol - Wikipedia
Acebutolol HCL Manufacturer, Supplier & Exporter
How Acebutolol Works and Treatment Instructions
Seasonal variations in the occurrence and fate of basic and neutral pharmaceuticals in a Swedish river-lake system
Mylan-Acebutolol - Pharmasave
Acebutolol (Oral Route) Proper Use - Mayo Clinic
Acebutolol capsules
Acebutolol capsules
Acebutolol - Neurology Advisor
acebutolol (CHEBI:2379)
Search Results - Fraser Health Patient Education Catalogue
Leki refundowane - Cena i zamienniki leku Sectral 400
Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial - Study Results - ClinicalTrials.gov
Apo-Acebutolol - Uses, Side Effects, Interactions - Canoe.com
Teva-Acebutolol - Uses, Side Effects, Interactions - MedBroadcast.com
Antianginalni lek - Wikipedia
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Chantix without insurance, Does Walmart Sell Amoxicillin Over The Counter www.pterodactilo.com Canada Pharmacy
Barbarian Xl shop - Молодёжный портал Зауралья
View source for Amlodipine and Atorvastatin drug interactions - wikidoc
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Chatterbox Psoriasis kaufen
Schedule H - Wikipedia
Cardiocirculatory effects of beta-adrenergic blockade in coronary artery disease at rest and during upright exercise:...
Antichromatin Antibodies | MCI Diagnostic Center, LLC
Hypertension Screening and Treatment Program - Full Text View - ClinicalTrials.gov
Hypertension - Anejo
Effect of chronic beta-adrenergic receptor blockade in congestive cardiomyopathy. | Heart
Beta-Adrenergic Receptor Blockade Propranolol and Related Drugs | Annals of Internal Medicine | American College of Physicians
Effects of acute and long-term beta-adrenoceptor blockade with...
Cardioselective vs. Non-cardioselective Beta Blockers - Video & Lesson Transcript | Study.com
The Effect of Exercise, Isoprenaline and Propranolol on Ejection Fraction as Determined by Nuclear Angiography | Clinical...
ICI-118,551
... is a selective β2 adrenergic receptor (adrenoreceptor) antagonist or beta blocker[1][2] . ICI binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor.[3][4] The compound was developed by Imperial Chemical Industries, which was acquired by AkzoNobel in 2008. ICI-118,551 has no known therapeutic use in humans although it has been used widely in research to understand the action of the β2 adrenergic receptor, as few other specific antagonists for this receptor are known.[5] ICI-118,551 has been used in pre-clinical studies using murine models.[6][7][8] When dissolved in saline, the compound crosses the blood-brain barrier. Common systemic doses used in rodent research are 0.5 or 1 mg/kg although efficacy has been demonstrated at doses as low as 0.0001 mg/kg in rhesus monkeys.[9] Doses up to 20 mg/kg have been used without toxicity. At room temperature in saline, the ICI 118,551 hydrochloride is soluble to ...
Ergoline
There are a variety of clinically useful ergoline derivatives for the purpose of vasoconstriction, the treatment of migraines, and treatment of Parkinson's disease. Ergoline alkaloids found their place in pharmacology long before modern medicine as preparations of ergot were often used by midwives in the 12th century to stimulate childbirth.[10] Following Arthur Stoll's isolation of ergometrine, the therapeutic use of ergoline derivatives became well explored. The induction of uterine contractions via the preparation of ergot was attributed to ergonovine, an ergoline derivative found in ergot, which is a powerful oxytocic. From this, methergine, a synthetic derivative, was elucidated.[7] While used to facilitate child birth, ergoline derivatives can pass into breast milk and should not be used during breastfeeding.[11] They are uterine contractors that can increase the risk of miscarriage during pregnancy.[3] Another example of medically relevant ergoline alkaloids is ergotamine, an alkaloid ...
Levobunolol
The most common side effect is eye irritation felt as stinging or burning, which occurs in up to a third of patients. Blepharoconjunctivitis occurs in up to 5% of patients. Rarer adverse effects include keratitis, edema and increased lacrimation.[2][3] Allergies are rare, but seem to be more common than under the related drug timolol.[1] If the substance reaches the nasal mucosa via the tear duct, it can be absorbed into the bloodstream and cause systemic side effects. These include orthostatic hypotension (low blood pressure) and other effects on the heart and circulatory system, breathing problems in people with asthma, and skin symptoms such as itching and aggravation of psoriasis.[1] ...
Capsinolol
InChI=1S/C23H40N2O4/c1-5-6-7-8-9-10-11-23(27)25-15-19-12-13-21(22(14-19)28-4)29-17-20(26)16-24-18(2)3/h12-14,18,20,24,26H,5-11,15-17H2,1-4H3,(H,25,27 ...
Etoperidone
... was discovered by scientists at Angelini, who also discovered trazodone.[15] Its development names have included ST-1191 and McN-A-2673-11.[16][1] The INN etoperidone was proposed in 1976 and recommended in 1977.[17][18] The drug was given brand names in Spain (Centren (Esteve) and Depraser (Lepori)) and Italy (Staff (Sigma Tau))[1] and was also given the brand names Axiomin and Etonin,[16] but it is not entirely clear if it was actually marketed; the Pharmaceutical Manufacturing Encyclopedia provides no dates for commercial introduction.[19] According to Micromedex's Index Nominum: International Drug Directory, etoperidone was indeed previously marketed in Spain and Italy.[1] ...
Amidephrine
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization ...
Idazoxan
... (INN) is a drug which is used in scientific research. It acts as both a selective α2 adrenergic receptor antagonist, and an antagonist for the imidazoline receptor.[1][2] Idazoxan has been under investigation as an antidepressant, but it did not reach the market as such. More recently, it is under investigation as an adjunctive treatment in schizophrenia. Due to its alpha-2 receptor antagonism it is capable of enhancing therapeutic effects of antipsychotics, possibly by enhancing dopamine neurotransmission in the prefrontal cortex of the brain, a brain area thought to be involved in the pathogenesis of schizophrenia. ...
Silodosin
Since silodosin has high affinity for the α1A adrenergic receptor, it causes practically no orthostatic hypotension (in contrast to other α1 blockers). On the other side, the high selectivity seems to be the cause of silodosin's typical side effect of loss of seminal emission.[3] As α1A adrenoceptor antagonists are being investigated as a means to male birth control due to their ability to inhibit ejaculation but not orgasm, a trial with 15 male volunteers was conducted. While silodosin was completely efficacious in preventing the release of semen in all subjects, 12 out of the 15 patients reported mild discomfort upon orgasm. The men also reported the psychosexual side effect of being strongly dissatisfied by their lack of ejaculation.[4] ...
Bromocriptine
Most frequent side effects are nausea, orthostatic hypotension, headaches, and vomiting through stimulation of the brainstem vomiting centre.[9] Vasospasms with serious consequences such as myocardial infarction and stroke that have been reported in connection with the puerperium, appear to be extremely rare events.[10] Peripheral vasospasm (of the fingers or toes) can cause Raynaud's Phenomenon. Bromocriptine use has been anecdotally associated with causing or worsening psychotic symptoms (its mechanism is in opposition of most antipsychotics, whose mechanisms generally block dopamine).[11] Pulmonary fibrosis has been reported when bromocriptine was used in high doses for the treatment of Parkinson's disease.[12] Use to suppress milk production after childbirth was reviewed in 2014 and it was concluded that in this context a causal association with serious cardiovascular, neurological or psychiatric events could not be excluded with an overall incidence rate estimated to range between 0.005% ...
Mesoridazine
... (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine. The drug's name is derived from the methylsulfoxy and piperidine functional groups in its chemical structure. It has central antiadrenergic, antidopaminergic, antiserotonergic and weak muscarinic anticholinergic effects. Serious side effects include akathisia, tardive dyskinesia and the potentially fatal neuroleptic malignant syndrome. Mesoridazine was withdrawn from the United States market in 2004 due to dangerous side effects, namely irregular heart beat and QT-prolongation of the electrocardiogram.[1] It currently appears to be unavailable worldwide. ...
3',4'-Methylenedioxy-α-pyrrolidinopropiophenone
... (MDPPP) is a stimulant designer drug. It was sold in Germany in the late 1990s and early 2000s as an ingredient in imitation ecstasy (MDMA) pills.[1] It shares a similar chemical structure with α-PPP and MDPV,[2][3][4] and has been shown to have reinforcing effects in rats.[5] ...
Trifluoperazine
Brand names include Eskazinyl, Eskazine, Jatroneural, Modalina, Stelazine, Terfluzine, Trifluoperaz, Triftazin. In the United Kingdom and some other countries, trifluoperazine is sold and marketed under the brand 'Stelazine'. The drug is sold as tablet, liquid and 'Trifluoperazine-injectable USP' for deep intramuscular short-term use. GP studying pharmacological data has indicated cases of neck vertebrae irreversible fusing leading to NHS preparations being predominantly of the liquid form trifluoperazine as opposed to the tablet form as in Stela zine etc. In the past, trifluoperazine was used in fixed combinations with the MAO inhibitor (antidepressant) tranylcypromine (tranylcypromine/trifluoperazine) to attenuate the strong stimulating effects of this antidepressant. This combination was sold under the brand name Jatrosom N. Likewise a combination with amobarbital (potent sedative/hypnotic agent) for the amelioration of psychoneurosis and insomnia existed under the brand name Jalonac. In ...
Terazosin
... (marketed as Hytrin or Zayasel) is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It also acts to lower the blood pressure, and is therefore a drug of choice for men with hypertension and prostate enlargement. It is available in 1 mg, 2 mg, 5 mg or 10 mg doses.[1] It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls. Most common side effects include dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion or dry eyes, but they generally go away after only a few days of use. Therapy should always be started with a low dose to avoid first dose phenomenon.[2] Sexual side effects are rare, but may include priapism or erectile dysfunction. ...
Tetryzoline
... eye drops may cause blurred vision, eye irritation and dilated pupils.[6] Tetryzoline is not suitable for prolonged use as its vasoconstrictive effects within the eye eventually decrease or stop. When body is accustomed to tetryzoline, ceasing its use may cause redness of the eyes.[7] Intranasal use of tetryzoline may cause transient burning, stinging, or dryness of the mucosa and sneezing. Prolonged intranasal use often causes opposite effects in the form of rebound congestion with effects such as chronic redness, swelling and rhinitis. Prolonged use thus may result in overuse of the drug.[6] Overdose most often causes slow heart rate. Respiratory depression, low blood pressure, constricted pupils, hypothermia, brief episodes of high blood pressure,[8] drowsiness, headaches and vomiting may also occur.[9] In serious cases some of these effects may result in circulatory shock.[6] Most often overdoses occur in children who have ingested the drug.[8] There is no antidote for ...
Zinterol
InChI=1S/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3 ...
Xylometazoline
The drug works by stimulating adrenergic receptors on the lamina propria of blood vessels in the nose. The decongestant effect is due to constriction of large veins in the nose which swell up during the inflammation of any infection or allergy of the nose. The smaller arteries are also constricted and this causes the colour of the nasal epithelium to be visibly paler after dosage. Xylometazoline is an imidazole derivative which is designed to mimic the molecular shape of adrenaline. It binds to α1 and α2 adrenergic receptors[8] in the nasal mucosa. Due to its sympathomimetic effects, it should not be used by people with high blood pressure, or other heart problems. Extended usage of xylometazoline can result in decreased effectiveness or a buildup of tolerance against the drug.[9] The number of receptors decreases, and when the administration of the drug is ceased, chronic congestion can occur; this is called rhinitis medicamentosa, commonly referred to as rebound congestion. Moreover, ...
Ipratropium bromide/salbutamol
Ipratropium/salbutamol, sold under the brand name Combivent among others, is a combination medication used to treat chronic obstructive pulmonary disease (COPD).[2][3] It contains ipratropium (an anticholinergic) and salbutamol (albuterol, a β2-adrenergic agonist).[2] It is taken by inhalation.[4] Common side effects include sore throat, muscle cramps, and nausea.[2] Other side effects may include bronchospasm, allergic reactions, and upper respiratory tract infections.[2] Safety in pregnancy is unclear.[1] Each medication typically decreases bronchospasm and does so via different mechanisms.[2] The combination was approved for medical use in the United States in 1996.[4] It is available as a generic medication.[3] Sixty doses in the United Kingdom costs the NHS about 18 £ as of 2019.[3] In the United States the wholesale cost of this amount is about US$9.50.[5] In 2016 it was the 166th most prescribed medication in the United States with more than 3 million prescriptions.[6] ...
Catecholaminergic
... means "related to catecholamines". The catecholamine neurotransmitters include dopamine, epinephrine (adrenaline), and norepinephrine (noradrenaline). A catecholaminergic agent (or drug) is a chemical which functions to directly modulate the catecholamine systems in the body or brain. Examples include adrenergics and dopaminergics. ...
Guanfacine
... works by activating α2A adrenoceptors in the central nervous system. This results in reduced peripheral sympathetic outflow and thus a reduction in peripheral sympathetic tone, which lowers both systolic and diastolic blood pressure.[13] In ADHD, guanfacine works by strengthening regulation of attention and behavior by the prefrontal cortex.[14] These enhancing effects on prefrontal cortical functions are thought to be due to drug stimulation of post-synaptic α2A adrenoceptors on dendritic spines, which inhibit cAMP-mediated opening of HCN and KCNQ channels and thus strengthen prefrontal cortical synaptic connectivity and enhance neuronal firing.[14][15] The use of guanfacine for treating prefrontal disorders was developed by the Arnsten lab at Yale University based on understanding the needs of the prefrontal cortex.[14][16] ...
Bunitrolol
Haddad, S; Poulin, P; Funk, C (2010). "Extrapolating in vitro metabolic interactions to isolated perfused liver: Predictions of metabolic interactions between R-bufuralol, bunitrolol, and debrisoquine". Journal of Pharmaceutical Sciences. 99 (10): 4406-26. doi:10.1002/jps.22136. PMID 20310018 ...
Procaterol
... is an intermediate-acting[citation needed] β2 adrenoreceptor agonist used for the treatment of asthma. It has never been filed for FDA evaluation in the United States, where it is not marketed. The drug is readily oxidized in the presence of moisture and air, making it unsuitable for therapeutic use by inhalation.[1] Pharmaceutical company Parke-Davis/Warner-Lambert researched a stabilizer to prevent oxidation, but an effective one was never developed.[1] It was patented in 1974 and came into medical use in 1980.[2] ...
Pipofezine
... , sold under the brand name Azafen or Azaphen, is an antidepressant approved in Russia for the treatment of depression.[1][2][3][4] It was introduced in the late 1960s and is still used today.[5][6] Pipofezine has been shown to act as a potent inhibitor of the reuptake of serotonin.[7][8] In addition to its antidepressant action, pipofezine has sedative effects as well, suggesting antihistamine activity.[4] Other properties such as anticholinergic or antiadrenergic actions are less clear but are likely.[citation needed] ...
Beta blocker
Some beta blockers (e.g. oxprenolol, pindolol, penbutolol, labetalol and acebutolol) exhibit intrinsic sympathomimetic activity ... Intermediate lipophilicity: metoprolol, bisoprolol, carvedilol, acebutolol, timolol, pindolol. *Low lipophilicity (also known ... Acebutolol,[81] pindolol,[81] labetalol,[81] mepindolol,[82] oxprenolol,[75] celiprolol,[76] penbutolol[72] ...
Moxisylyte
... , also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction.[1] It is an α1-adrenergic antagonist.[2] In the United Kingdom, Moxisylte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for the short-term treatment of primary Reynaud's syndrome. This is a condition where the fingers and toes become discoloured and is triggered by responses to cold, or emotional distress. Opilon tablets help by improving blood circulation to the extremities.[3][4] ...
Phenylisobutylamine
... , also known as α-ethylphenethylamine, Butanphenamine, B or AEPEA,[1] is a stimulant drug of the phenethylamine class. It is a higher homologue of amphetamine, differing from amphetamine's molecular structure only by the substitution of the methyl group at the alpha position of the side chain with an ethyl group. Compared to amphetamine, phenylisobutylamine has strongly reduced dopaminergic effects, and instead acts as a selective norepinephrine releasing agent.[citation needed] The dextroisomer of phenylisobutylamine partially substitutes for dextroamphetamine in rats.[1] A number of derivatives of phenylisobutylamine are known, including BDB, MBDB, EBDB, butylone (bk-MBDB), eutylone (bk-EBDB), Ariadne (α-Et-DOM), 4-CAB, and 4-MAB. "Phenylisobutylamine" is in fact a chemical misnomer because isobutylamine itself contains a branched chain. The correct name after this style for this class of compound would be "phenylsecbutylamine". ...
Tamsulosin
In a retrospective analysis of 388 patients with HF (heart failure) and benign prostatic hypertrophy receiving alpha blockers, including prazosin, terazosin, doxazosin, or tamsulosin, Dhaliwal and colleagues found no significant increase in all-cause mortality and HF re-hospitalization in those also receiving β-blockers. However, in those not receiving β-blockade, α-blockade exposure was associated with an increase in HF hospitalization (HR, 1.94; 95% CI, 1.14-3.32). Of note, the majority of patients were receiving tamsulosin (58%). It has been hypothesized that unopposed α1 blockade could lead to β1-receptor stimulation with increases in renin and aldosterone, leading to edema and weight gain. Chronic α1 antagonism may lead to tachyphylaxis according to the American Heart Association ([1] Drugs That May Cause or Exacerbate Heart Failure, A Scientific Statement From the American Heart Association, Urological Medications). Additionally, several reasons have been proposed for an increased ...
Diacetolol
... is the primary metabolite of acebutolol. It is a beta blocker and anti-arrhythmic agent. Basil B, Jordan R (May 1982 ... "Pharmacological properties of diacetolol (M & B 16,942), a major metabolite of acebutolol". European Journal of Pharmacology. ...
Amidefrin - Википедија, слободна енциклопедија
Drugbox-lat , verifiedrevid = 443383199 , IUPAC_name =(RS)-N-{3-[1-hidroksi-2-(metilamino)etil]fenil}metanesulfonamid , image = Amidephrine.svg , width = , image2 = , width2 =. , tradename = , pregnancy_category = , legal_status = , routes_of_administration =. , bioavailability = , metabolism = , elimination_half-life = , excretion =. , CAS_number_Ref = ...
Abanohil - Википедија
InChI=1S/C22H25N3O4/c1-26-18-7-13-5-6-25(12-14(13)8-19(18)27-2)22-10-16(23)15-9-20(28-3)21(29-4)11-17(15)24-22/h7-11H,5-6,12H2,1-4H3,(H2,23,24) ...
Rauvolscin - Википедија, слободна енциклопедија
InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1 ...
acebutolol (CHEBI:2379)
... is a aromatic amide (CHEBI:62733) acebutolol (CHEBI:2379) is a ethanolamines (CHEBI:23981) acebutolol ( ... acebutolol (CHEBI:2379) is a secondary amino compound (CHEBI:50995) acebutolol (CHEBI:2379) is conjugate base of acebutolol(1+ ... acebutolol (CHEBI:2379) is a monocarboxylic acid amide (CHEBI:29347) acebutolol (CHEBI:2379) is a propanolamine (CHEBI:35533) ... acebutolol (CHEBI:2379) has role β-adrenergic antagonist (CHEBI:35530) acebutolol (CHEBI:2379) has role anti-arrhythmia drug ( ...
Acebutolol: MedlinePlus Drug Information
Acebutolol: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Acebutolol is used to treat high blood pressure. Acebutolol also is used to treat an irregular heartbeat. Acebutolol is in a ... Acebutolol controls your condition but does not cure it. Continue to take acebutolol even if you feel well. Do not stop taking ... Before taking acebutolol,. *tell your doctor and pharmacist if you are allergic to acebutolol, any other medications, or any ...
Sectral (acebutolol)
Acebutolol is also available without a brand name, ie as the generic medicine. ... Sectral capsules and tablets contain the active ingredient acebutolol, which is a type of medicine called a beta-blocker. ... Acebutolol can therefore be used to lower high blood pressure.. Acebutolols action in slowing the rate and force of the ... Sectral (acebutolol). Sectral capsules and tablets contain the active ingredient acebutolol, which is a type of medicine called ...
Acebutolol - Wikipedia
Acebutolol has a half-life of 3 to 4 hours, and diacetolol a half-life of 8 to 13 hours. Acebutolol undergoes extensive hepatic ... Acebutolol, sold under the brand names Sectral among others, is a beta blocker for the treatment of hypertension and ... Acebutolol has no negative impact on serum lipids (cholesterol and triglycerides). No HDL decrease has been observed. In this ... Acebutolol is a cardioselective beta-1 blocker which also considered a partial agonist due to its intrinsic sympathomimetic ...
Acebutolol - definition of acebutolol by The Free Dictionary
acebutolol synonyms, acebutolol pronunciation, acebutolol translation, English dictionary definition of acebutolol. n. A beta- ... acebutolol. Also found in: Thesaurus, Medical, Wikipedia.. Related to acebutolol: Acebutolol hydrochloride ... Acebutolol - definition of acebutolol by The Free Dictionary https://www.thefreedictionary.com/acebutolol ... 17] found labetalol 1 mg/kg more effective when compared with acebutolol 0.25 mg/kg and lidocaine 2 mg/kg for attenuation of ...
acebutolol Information - Drugs and Treatments - MedHelp
Before taking acebutolol, tell your doctor or pharmacist if you are allergic to it; or to other beta-blockers (e.g., ... Acebutolol is used alone or with other medications to treat high blood pressure and irregular heartbeat (arrhythmia). Lowering ... If you are currently using this medication, tell your doctor or pharmacist before starting acebutolol. Before using this ...
DailyMed - ACEBUTOLOL HYDROCHLORIDE capsule
Acebutolol HCl capsules, USP are provided in two dosage strengths which contain 200 mg or 400 mg of acebutolol as the ... Acebutolol should be used cautiously in patients with impaired hepatic function.. Acebutolol has been used successfully and ... Acebutolol and diacetolol were also shown to be devoid of mutagenic potential in the Ames Test. Acebutolol, administered orally ... Both digitalis and acebutolol impair AV conduction. If cardiac failure persists, therapy with acebutolol should be withdrawn. ...
Acebutolol (Oral Route) Proper Use - Mayo Clinic
Information about this acebutolol-oral-route. Pregnancy Category. Explanation. All Trimesters. B. Animal studies have revealed ... Acebutolol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or ... Acebutolol is used alone or together with other medicines (such as hydrochlorothiazide) to treat high blood pressure ( ... Appropriate studies have not been performed on the relationship of age to the effects of acebutolol in the pediatric population ...
Acebutolol: Side Effects, Dosage, Uses and More
Its also used to treat premature ventricular contractions (PVCs). Acebutolol oral capsule is available as a generic drug and ... Acebutolol oral capsule is a prescription medication used to treat high blood pressure. ... Take acebutolol at the same time each day.. Storage. *Store acebutolol at room temperature between 68°F (20°C) and 77°F (25°C). ... Acebutolol is a prescription drug. It comes as an oral capsule.. Acebutolol oral capsule is available as the brand-name drug ...
Acebutolol - FDA prescribing information, side effects and uses
Acebutolol official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, ... How is Acebutolol Supplied. Acebutolol HCl capsules, USP are available as follows:. 200 mg: Hard gelatin capsules with bright ... Acebutolol HCl capsules, USP are provided in two dosage strengths which contain 200 mg or 400 mg of Acebutolol as the ... Acebutolol should be used cautiously in patients with impaired hepatic function.. Acebutolol has been used successfully and ...
Sectral (Acebutolol): Side Effects, Interactions, Warning, Dosage & Uses
Acebutolol) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related ... acebutolol hydrochloride) Capsules. DESCRIPTION. Sectral (acebutolol HCl) is a selective, hydrophilic beta-adrenoreceptor ... Sectral® (acebutolol HCl) is available in the following dosage strengths:. 200 mg, opaque purple and orange capsule marked "RP ... Foreign published experience shows that acebutolol has been used successfully in chronic renal insufficiency. Acebutolol is ...
DailyMed - ACEBUTOLOL HYDROCHLORIDE - acebutolol hydrochloride capsule
ACEBUTOLOL HYDROCHLORIDE - acebutolol hydrochloride capsule Number of versions: 7. Published Date (What is this?). Version. ... ACEBUTOLOL HYDROCHLORIDE - acebutolol hydrochloride capsule To receive this label RSS feed. Copy the URL below and paste it ... Acebutolol HCl, USP capsules are provided in two dosage strengths which contain 200 or 400 mg of acebutolol as the ... Acebutolol should be used cautiously in patients with impaired hepatic function.. Acebutolol has been used successfully and ...
Acebutolol - Википедија, слободна енциклопедија
Acebutolol (Sektral, Prent) je beta blokator za tretman hipertenzije i aritmija.[1][2] ... Acebutolol je kardioselektivni beta blokator sa intrinsičnom simpatomimetičkom aktivnošću. On je stoga podesniji od beta ... Преузето из „https://sr.wikipedia.org/w/index.php?title=Acebutolol&oldid=14776498" ...
Acebutolol - Wikipedia
Acebutolol (Sektral, Prent) je beta blokator za tretman hipertenzije i aritmija.[6][7] ... Antagonisti: Acebutolol • Adaprolol • Adimolol • Afurolol • Alprenolol • Alprenoksim • Amosulalol • Ankarolol • Arnolol • ... Acebutolol je kardioselektivni beta blokator sa intrinsičnom simpatomimetičkom aktivnošću. On je stoga podesniji od beta ... Dobavljeno iz "https://sh.wikipedia.org/w/index.php?title=Acebutolol&oldid=3777782" ...
Sectral (Acebutolol) Side effects, Images, Uses, Dosage, Overdose at RxList
Acebutolol)? Learn about drug imprint, side effects, uses (treating), dosage, interaction, overdose, and warnings. ... What is acebutolol (Sectral)?. Acebutolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through ... You should not use acebutolol if you have a serious heart condition such as "AV block" (2nd or 3rd degree), severe heart ... What are the possible side effects of acebutolol (Sectral)?. Get emergency medical help if you have signs of an allergic ...
Acebutolol Interaction with Food, Herbs, Alcohol and Caffeine
Caffeine when taking Acebutolol. Drug interaction with any of these substances may enhance or decrease the effect of Acebutolol ... Acebutolol Interactions with Food and Herbs. Potassium Rich Foods: Acebutolol is a beta blocker which increases the potassium ... How to Take the Medication - Acebutolol Acebutolol is available in the form of a capsule. You can take it 1-2 times in a day. ... Acebutolol Interactions with Alcohol. The intake of acebutolol with alcohol can increase the feeling of dizziness or faintness. ...
acebutolol - WellSpan Health Library
Beta-blockers affect the heart and circulation (blood flow through arteries and veins). Acebutolol is used to treat ... Acebutolol may also be used for purposes not listed in this medication guide. ... What is the most important information I should know about acebutolol?. You should not use acebutolol if you have a serious ... What is acebutolol?. Acebutolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries ...
Mylan Acebutolol S - Uniprix
Apo-Acebutolol - Uses, Side Effects, Interactions - MedBroadcast.com
Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ... 02147602 APO-ACEBUTOLOL 100MG TABLET. 02147610 APO-ACEBUTOLOL 200MG TABLET. 02147629 APO-ACEBUTOLOL 400MG TABLET. ... The usual adult starting dose of acebutolol to treat high blood pressure is 100 mg taken twice daily. After a week, your doctor ... Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ...
Teva-Acebutolol - Uses, Side Effects, Interactions - MedBroadcast.com
Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ... 02204517 TEVA-ACEBUTOLOL 100MG TABLET. 02204525 TEVA-ACEBUTOLOL 200MG TABLET. 02204533 TEVA-ACEBUTOLOL 400MG TABLET. ... The usual adult starting dose of acebutolol to treat high blood pressure is 100 mg taken twice daily. After a week, your doctor ... Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ...
Acebutolol HCl | definition of acebutolol HCl by Medical dictionary
... acebutolol HCl explanation free. What is acebutolol HCl? Meaning of acebutolol HCl medical term. What does acebutolol HCl mean? ... Looking for online definition of acebutolol HCl in the Medical Dictionary? ... acebutolol HCl. acebutolol HCl (as´əbyōō´təlôl),. n brand names: Monitan, Sectral; drug class: antihypertensive, selective β1 ... Acebutolol HCl , definition of acebutolol HCl by Medical dictionary https://medical-dictionary.thefreedictionary.com/acebutolol ...
Acebutolol capsules - AHealthyMe - Blue Cross Blue Shield of Massachusetts
Acebutolol
- Prent
Summary Report | CureHunter
Acebutolol: A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has ... Prent; Sectral; Acebutolol Heumann; Acebutolol Hydrochloride; Acetobutolol; Acébutolol-ratiopharm; Apo-Acebutolol; Apotex Brand ... Specia Brand of Acebutolol Hydrochloride; Wyeth Brand of Acebutolol Hydrochloride; Acebutolol Gepepharm Brand; Acébutolol ... Acebutolol; Lafon Ratiopharm Brand of Acebutolol Hydrochloride; M&B 17803 A; M&B17803 A; Novo Acebutolol; NovoAcebutolol; Rhône ...
Sandoz Acebutolol - Uses, Side Effects, Interactions - Canada.com
Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ... 02257599 SANDOZ ACEBUTOLOL TABLETS 100 MG. 02257602 SANDOZ ACEBUTOLOL TABLETS 200 MG. 02257610 SANDOZ ACEBUTOLOL TABLETS 400 MG ... The usual adult starting dose of acebutolol to treat high blood pressure is 100 mg taken twice daily. After a week, your doctor ... Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ...
Ava-Acebutolol - Uses, Side Effects, Interactions - Canada.com
Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ... The usual adult starting dose of acebutolol to treat high blood pressure is 100 mg taken twice daily. After a week, your doctor ... Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ... Ava-Acebutolol is no longer being manufactured for sale in Canada. For brands that may still be available, search under ...
Mylan-Acebutolol - Pharmasave
The usual adult starting dose of acebutolol to treat high blood pressure is 100 mg taken twice daily. After a week, your doctor ... Acebutolol belongs to the class of medications called beta-blockers. It is used to treat mild-to-moderate high blood pressure ... Acebutolol can be taken with or without food.. Many things can affect the dose of a medication that a person needs, such as ... Low doses of acebutolol may be used with caution by people with asthma who do not respond to or who cannot tolerate other ...
Acebutolol | Profiles RNS
"Acebutolol" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Effects of acebutolol on chronic stable angina pectoris. A placebo-controlled, double-blind, randomized crossover study. ... This graph shows the total number of publications written about "Acebutolol" by people in this website by year, and whether " ... Below are the most recent publications written about "Acebutolol" by people in Profiles. ...
Types of Acebutolol Hydrochloride -- Teratogenic Agent - RightDiagnosis.com
Types of Acebutolol Hydrochloride - Teratogenic Agent including less common types and symptoms and diagnosis of the correct ... Symptoms: Acebutolol Hydrochloride -- Teratogenic Agent » Next page: Causes of Acebutolol Hydrochloride -- Teratogenic Agent ... Diagnostic Tests for Acebutolol Hydrochloride -- Teratogenic Agent. *Home Diagnostic Testing for Acebutolol Hydrochloride -- ... Treatments for Acebutolol Hydrochloride -- Teratogenic Agent. *Doctors and Medical Specialists for Acebutolol Hydrochloride -- ...
Efficacy and Safety of Propranolol Versus Acebutolol on the Proliferative Phase of Infantile Hemangioma
SectralPropranololCardioselective beta-blockerPlasma levels of acebutololStop taking aceAdministration of acebutololHypertensionPrentOralInteractionsPregnant while taking aceCapsulesDrugsDosage of acebutololTreatment with acebutololChronicDiacetololTake acebutololMedicationHypersensitivityBeta-adrenoreceptorMyocardial infarctionDoseMajor metaboliteEquipotentReduces the heart'sTABLETSide effectsArterialAntihypertensive effectGenericHeart'sAllergicIntrinsic sympathomimeticAnginaPregnancyByooDiureticsCapsule formClinicalDoses
Sectral7
- Sectral capsules and tablets contain the active ingredient acebutolol, which is a type of medicine called a beta-blocker. (netdoctor.co.uk)
- Acebutolol, sold under the brand names Sectral among others, is a beta blocker for the treatment of hypertension and arrhythmias. (wikipedia.org)
- What is acebutolol (Sectral)? (rxlist.com)
- What are the possible side effects of acebutolol (Sectral)? (rxlist.com)
- What is the most important information I should know about acebutolol (Sectral)? (rxlist.com)
- What should I discuss with my healthcare provider before taking acebutolol (Sectral)? (rxlist.com)
- How should I take acebutolol (Sectral)? (rxlist.com)
Propranolol12
- The incidence of both ANA and symptomatic disease under acebutolol is higher than under propranolol. (wikipedia.org)
- Cardiosseletivos Nao seletivos Drogas com atividade al antagonista adicional Acebutolol * Alprenolol * Bucindolol Atenolol Carteolol * Carvedilol Betaxolol Nadolol Labetalol Bevantolol Oxprenolol * Bisoprolol Penbutolol * Celiprolol Pindolol * Esmolol Propranolol Metoprolol Sotalol Practolol * Timolol Quadro 4: Criterios usados na selecao e forma de obtencao dos dados. (thefreedictionary.com)
- Segundo a SOGC, (6) o tratamento inicial da hipertensao leve a moderada pode ser feito com metildopa, labetalol, outros betabloqueadores ( acebutolol , metoprolol, pindolol e propranolol) e bloqueadores do canal de calcio (nifedipina) (C). (thefreedictionary.com)
- Bronchial Effects: In single-dose studies in asthmatics examining effects of various beta-blockers on pulmonary function, low doses of acebutolol produce less evidence of bronchoconstriction and less reduction of beta2 agonist, bronchodilating effects, than nonselective agents like propranolol but more than atenolol. (nih.gov)
- ISA has been observed with acebutolol in man, as shown by a slightly smaller (about 3 beats per minute) decrease in resting heart rate when compared to equivalent β-blocking doses of propranolol, metoprolol or atenolol. (nih.gov)
- The antihypertensive effect of Acebutolol has been shown in double-blind controlled studies to be superior to placebo and similar to propranolol and hydrochlorothiazide. (drugs.com)
- The antiarrhythmic effect of Acebutolol was compared with placebo, propranolol, and quinidine. (drugs.com)
- Kaku, R, Lee, G & Amsterdam, EA 1978, ' Cardiocirculatory effects of beta-adrenergic blockade in coronary artery disease at rest and during upright exercise: comparison of acebutolol and propranolol ', Clinical Research , vol. 26, no. 2. (elsevier.com)
- I had tried metoprolol, propranolol, nebivolol and acebutolol. (dinet.org)
- In eight patients (group II) in whom supine bicycle exercise produced increases in LVEF, both acebutolol (58.8 ± 5.4% versus 53.8 ± 4.4%) and propranolol (57.8 ± 5.7% versus 54.1 ± 4.9%) attenuated the increases. (elsevier.com)
- In neither group was the resting LVEF reduced by acebutolol or propranolol. (elsevier.com)
- The data show that acebutolol and propranolol are approximately equipotent in minimizing the radionuclide left ventriculographic manifestations of myocardial ischemia induced by supine bicycle exercise. (elsevier.com)
Cardioselective beta-blocker1
- A cardioselective beta-blocker, acebutolol is used as the hydrochloride salt for the management of hypertension, angina pectoris, and cardiac arrhythmias. (ebi.ac.uk)
Plasma levels of acebutolol3
- Peak plasma levels of acebutolol are reached within 2 to 2.5 hours after oral dosing. (wikipedia.org)
- There are significant correlations between plasma levels of acebutolol and both the reduction in resting heart rate and the percent of β-blockade of exercise-induced tachycardia. (nih.gov)
- Use photocopies of fluoroquinolones including tibolone can lead to increase in plasma levels of acebutolol when used concurrently. (info-web-directory.com)
Stop taking ace2
- Do not stop taking acebutolol without talking to your doctor. (medlineplus.gov)
- If you suddenly stop taking acebutolol, you may experience serious heart problems such as angina (chest pain) or heart attack. (medlineplus.gov)
Administration of acebutolol2
- Administration of methimazole did not affect digoxin pharma-co-kinetics, administration of acebutolol resulted in an increased serum digoxin concentration and in a longer time to the peak serum level of digoxin in comparison with the control group. (endocrine-abstracts.org)
- The time to reach peak concentration for acebutolol is 2.5 hours and for diacetolol, after oral administration of acebutolol hydrochloride, 3.5 hours. (abouthealthus.com)
Hypertension7
- Hypertension Ventricular and atrial cardiac arrhythmia Acute myocardial infarction in high-risk patients Smith-Magenis syndrome Stable or unstable angina (due to its partial agonist or ISA activity) The development of anti-nuclear antibodies (ANA) has been found in 10 to 30% of patients under treatment with acebutolol. (wikipedia.org)
- Acebutolol HCl, USP is a selective, hydrophilic beta-adrenoreceptor blocking agent with mild intrinsic sympathomimetic activity for use in treating patients with hypertension and ventricular arrhythmias. (nih.gov)
- Acebutolol is used alone or together with other medicines (such as hydrochlorothiazide) to treat high blood pressure (hypertension). (mayoclinic.org)
- Acebutolol is used to treat high blood pressure (hypertension) and a type of irregular heart rhythm (premature ventricular contractions, or PVCs). (healthline.com)
- Acebutolol is used to treat hypertension ( high blood pressure ) and heart rhythm disorders . (rxlist.com)
- Acebutolol is a medication used to treat hypertension and cardiac arrhythmias. (wordpress.com)
- Our results suggest that Acebutolol, an FDA-approved beta blocker for hypertension therapy, could have a new repurposed effect on type 2 diabetes elevating glucose uptake process by inhibiting JNK-JIP1 interaction. (biomolther.org)
Prent1
- Acebutolol ( Sektral , Prent ) je beta blokator za tretman hipertenzije i aritmija . (wikipedia.org)
Oral8
- What does ACEBUTOLOL - ORAL look like? (medhelp.org)
- Acebutolol oral capsule is available as a generic drug and a brand-name drug. (healthline.com)
- Acebutolol only comes as an oral capsule. (healthline.com)
- Acebutolol oral capsule does not cause drowsiness, but it can cause other side effects. (healthline.com)
- Acebutolol oral capsule can interact with other medications, vitamins, or herbs you may be taking. (healthline.com)
- 2. Does simultaneous administration of digoxin and methimazole or digoxin and acebutolol affect the pharmacokinetics of a single oral dose of dogoxin? (endocrine-abstracts.org)
- 4. Does acebutolol, which ameliorates symptoms of hyperkinetic circulation change the pharmacokinetics of a single oral dose of dogoxin? (endocrine-abstracts.org)
- The kinetics of acebutolol were not significantly altered by concomitant administration of hydrochlorothiazide, hydralazine, sulfinpyrazone, or oral contraceptives. (abouthealthus.com)
Interactions1
- Examples of drugs that can cause interactions with acebutolol are listed below. (healthline.com)
Pregnant while taking ace2
- If you become pregnant while taking acebutolol, call your doctor. (medlineplus.gov)
- Tell your doctor if you are pregnant or plan to become pregnant while taking acebutolol. (rxlist.com)
Capsules2
- tell your doctor and pharmacist if you are allergic to acebutolol, any other medications, or any ingredients in acebutolol capsules. (medlineplus.gov)
- Acebutolol HCl capsules, USP are provided in two dosage strengths which contain 200 mg or 400 mg of acebutolol as the hydrochloride salt. (nih.gov)
Drugs3
- Sympathomimetic drugs, of quinidinic type, such as Acebutolol (13). (thefreedictionary.com)
- Acebutolol belongs to a class of drugs called beta-blockers . (healthline.com)
- Nonsteroidal anti-inflammatory drugs (NSAIDs) may decrease the blood pressure-lowering effect of acebutolol. (healthline.com)
Dosage of acebutolol2
- The usual starting dosage of acebutolol for the treatment of high blood pressure is 400 mg once daily. (emedtv.com)
- If you are unsure about anything related to your dosage of acebutolol, please talk with your doctor, nurse, or pharmacist. (emedtv.com)
Treatment with acebutolol3
- Long-term treatment after myocardial infarction: treatment with acebutolol should preferably be instituted between the 3 rd and the 21 st day after the acute episode of infarction: the dosage is 2 tablets per day, in two doses. (healthician.org)
- In the case of treatment with acebutolol, breast-feeding is contraindicated due to a significant passage of milk (see section on pharmacokinetic properties). (healthician.org)
- The development of anti-nuclear antibodies (ANA) has been found in 10 to 30% of patients under treatment with acebutolol. (pharmacyreviewer.co)
Chronic3
- Due to its cardioselectivity, Acebutolol is more suitable than non-cardioselective beta-blockers, in a patient with asthma or chronic obstructive pulmonary disease (COPD) who needs treatment with a beta-blocker. (wikipedia.org)
- Chronic therapy with acebutolol induced no significant alteration in the blood lipid profile. (nih.gov)
- Acebutolol is a cardio selective beta blocker with intrinsic sympathomimetic activity, and so is infinitely more suitable than non-cardioselective beta blockers for patients with chronic obstructive pulmonary disease or asthma due to the fact that doses lower than 800mg daily have only 10-30% of the constricting effects on the bronchial system that treatments such as propanolol may have. (wordpress.com)
Diacetolol10
- Acebutolol has a half-life of 3 to 4 hours, and diacetolol a half-life of 8 to 13 hours. (wikipedia.org)
- Acebutolol undergoes extensive hepatic metabolization resulting in the desbutyl amine acetolol which is readily converted into diacetolol. (wikipedia.org)
- Diacetolol is as active as acebutolol (equipotency) and appears to have the same pharmacologic profile. (wikipedia.org)
- Geriatric patients tend to have higher peak plasma levels of both acebutolol and diacetolol and a slightly prolonged excretion. (wikipedia.org)
- T max is 2.5 h (acebutolol) and 3.5 h (diacetolol). (drugster.info)
- T ½ is about 3 to 4 h (acebutolol) and 8 to 13 h (diacetolol). (drugster.info)
- The plasma elimination half-life of acebutolol is approximately 3 to 4 hours, while that of its metabolite, diacetolol, is 8 to 13 hours. (abouthealthus.com)
- Acebutolol and its metabolite, diacetolol, are relatively hydrophilic and, therefore, only minimal quantities have been detected in the cerebrospinal fluid (CSF). (abouthealthus.com)
- In patients with renal impairment, there is no effect on the elimination half-life of acebutolol, but there is decreased elimination of the metabolite, diacetolol, resulting in a two- to three-fold increase in its half-life. (abouthealthus.com)
- Diacetolol is the primary metabolite of acebutolol. (wikipedia.org)
Take acebutolol3
- To help you remember to take acebutolol, take it around the same time(s) every day. (medlineplus.gov)
- Take acebutolol exactly as directed. (medlineplus.gov)
- Continue to take acebutolol even if you feel well. (medlineplus.gov)
Medication4
- If you are currently using this medication, tell your doctor or pharmacist before starting acebutolol. (medhelp.org)
- Acebutolol may also be used for purposes not listed in this medication guide. (rxlist.com)
- Acebutolol interaction with Food, Herbs, Alcohol and Caffeine - It is important to know how to take the medication to avoid the drug-food interaction. (medindia.net)
- Some of the side effects of acebutolol do not constitute medical emergencies and do go away as the body continues to adjust to the medication. (healthery.com)
Hypersensitivity1
- Acebutolol induced hypersensitivity pneumonitis. (pneumotox.com)
Beta-adrenoreceptor2
- Nandibewoor, "Electroanalysis of cardioselective beta-adrenoreceptor blocking agent acebutolol by disposable graphite pencil electrodes with detailed redox mechanism," Cogent Chemistry, vol. (thefreedictionary.com)
- Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. (abouthealthus.com)
Myocardial infarction2
- Long-term treatment after myocardial infarction (acebutolol decreases the risk of recurrence, myocardial infarction and mortality, particularly sudden death). (healthician.org)
- Prophylaxis of stress angina attacks · Long-term treatment after myocardial infarction (acebutolol decreases the risk of recurrence, myocardial infarction and mortality, especially (Tachycardia, flutters and atrial fibrillation, tachycardia, junctional) or ventricular (ventricular extrasystolia, ventricular tachycardia). (healthician.org)
Dose6
- Acebutolol is a cardioselective, β-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. (nih.gov)
- The usual adult starting dose of acebutolol to treat high blood pressure is 100 mg taken twice daily. (medbroadcast.com)
- Sixteen acebutolol-treated patients were re-asessed once symptoms of hyperkinetic circulation had subsided.Moreover we evaluated pharmacokinetics of a single dose of digoxin after simultaneous administration of digoxin and methimazole or digoxin and acebutolol. (endocrine-abstracts.org)
- Also, your healthcare provider may slowly increase your dose up to a maximum of acebutolol 600 mg twice daily if necessary. (emedtv.com)
- The recommended starting dose of acebutolol for controlling an irregular heart rhythm (arrhythmia) is 200 mg twice daily. (emedtv.com)
- the usual daily dose of acebutolol is 400 mg which will be administered either preferably in a single dose each morning, or in two doses, one in the morning and one in the evening (there is a 200 mg dosage form). (my-breath.com)
Major metabolite1
- Acebutolol and its major metabolite are dialyzable. (abouthealthus.com)
Equipotent1
- equipotent to acebutolol). (drugster.info)
Reduces the heart's2
- This reduces the heart's need for oxygen, which means that acebutolol can also be used in the management of angina. (netdoctor.co.uk)
- Acebutolol also reduces the heart's demand for oxygen. (healthery.com)
TABLET4
- Each white, round, film-coated tablet, scored and engraved 'APO' over '100' on one side, contains 100 mg of acebutolol. (medbroadcast.com)
- Each cream-coloured, scored, oblong, film-coated tablet, marked 'novo' on one side and '400' on the other, contains 400 mg of acebutolol. (medbroadcast.com)
- Each normal convex, round, film-coated, white tablet engraved 'AC/100' on one side and 'G' on the other, contains 100 mg of acebutolol. (pharmasave.com)
- Acebutolol is administered orally and is presented as a tablet or capsule. (healthery.com)
Side effects2
- Acebutolol may cause side effects. (medlineplus.gov)
- Altogether, 5 to 6% of all patients treated have to discontinue acebutolol due to intolerable side effects. (wikipedia.org)
Arterial2
- Acebutolol may precipitate or aggravate symptoms of arterial insufficiency. (drugster.info)
- Tratamiento de la hipertension arterial esencial con acebutolol en dosis unica diaria. (bvsalud.org)
Antihypertensive effect1
- Avoid consuming caffeine-containing products like tea or coffee along with acebutolol as caffeine has the ability to decrease the antihypertensive effect of the drug. (medindia.net)
Generic1
- Acebutolol is also available without a brand name, ie as the generic medicine. (netdoctor.co.uk)
Heart's1
- Acebutolol also helps to lower your heart rate and your heart's demand for oxygen. (healthline.com)
Allergic1
- A doctor should be immediately informed if any signs of allergic reaction to acebutolol occur while ingesting the drug. (healthery.com)
Intrinsic sympathomimetic4
- A third vasodilatory mechanism, as in pindolol and acebutolol , acts via [beta]2-intrinsic sympathomimetic activity. (thefreedictionary.com)
- Acebutolol is a selective, hydrophilic beta-blocking drug, as well as a class II antiarrhythmic agent with mild, intrinsic sympathomimetic activity. (medscape.com)
- https://en.wikipedia.org/wiki/Beta_blocker#Intrinsic_sympathomimetic_activity I stopped taking it after my blood sugars started to raise and I was worried it was playing a role in it. (dinet.org)
- Acebutolol is a new investigational β-antagonist which has intrinsic sympathomimetic and cardioselective properties. (elsevier.com)
Angina1
- Acebutolol is also used sometimes to treat chest pain (angina). (medlineplus.gov)
Pregnancy1
- However, taking acebutolol during pregnancy may cause problems after the baby is born. (rxlist.com)
Byoo1
- ACEBUTOLOL (a se BYOO toe lole) is a beta-blocker. (ahealthyme.com)
Diuretics1
- Acebutolol is particularly suitable for antihypertensive combination treatment with diuretics, if acebutolol alone proves insufficient. (pharmacyreviewer.co)
Capsule form1
- Acebutolol comes in capsule form. (emedtv.com)
Clinical2
- Acebutolol may mask clinical signs of developing or continuing hyperthyroidism (eg, tachycardia). (drugster.info)
- In some countries injectable forms for i.v.-injection with 25mg acebutolol exist, but these are only for cases of emergency under strict clinical monitoring. (pharmacyreviewer.co)
Doses1
- The membrane-stabilizing effect of acebutolol is not manifest at the doses used clinically. (nih.gov)