AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
AcanthamoebaAcanthamoeba KeratitisAcanthamoeba castellaniiAmoebaAmebiasisContact LensesAmebicidesContact Lens SolutionsRNA, Ribosomal, 18SNaegleriaTrophozoitesMimiviridaeBiguanidesDNA, ProtozoanKeratitisCentral Nervous System Protozoal InfectionsContact Lenses, HydrophilicProfilinsChlamydialesDisinfectantsMyosinsCorneaCa(2+) Mg(2+)-ATPaseHartmannellaProtozoan ProteinsLegionella pneumophilaAntiprotozoal AgentsBenzamidinesContractile ProteinsRNA, ProtozoanMethylmannosidesEncephalitisActinsCorneal UlcerMethylophilusDisinfectionMeningoencephalitisChlorhexidineSpores, ProtozoanEncyclopedias as Topic
Acanthamoeba
A genus of free-living soil amoebae that produces no flagellate stage. Its organisms are pathogens for several infections in humans and have been found in the eye, bone, brain, and respiratory tract.
Acanthamoeba Keratitis
Infection of the cornea by an ameboid protozoan which may cause corneal ulceration leading to blindness.
Acanthamoeba castellanii
A species of free-living soil amoebae in the family Acanthamoebidae. It can cause ENCEPHALITIS and KERATITIS in humans.
Amoeba
A genus of ameboid protozoa. Characteristics include a vesicular nucleus and the formation of several lodopodia, one of which is dominant at a given time. Reproduction occurs asexually by binary fission.
Amebiasis
Infection with any of various amebae. It is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.
Contact Lenses
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
Amebicides
Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal.
Contact Lens Solutions
Sterile solutions used to clean and disinfect contact lenses.
RNA, Ribosomal, 18S
Constituent of the 40S subunit of eukaryotic ribosomes. 18S rRNA is involved in the initiation of polypeptide synthesis in eukaryotes.
Naegleria
A free-living soil amoeba pathogenic to humans and animals. It occurs also in water and sewage. The most commonly found species in man is NAEGLERIA FOWLERI which is the pathogen for primary amebic meningoencephalitis in primates.
Trophozoites
Cells or feeding stage in the life cycle of sporozoan protozoa. In the malarial parasite, the trophozoite develops from the MEROZOITE and then splits into the SCHIZONT. Trophozoites that are left over from cell division can go on to form gametocytes.
Mimiviridae
A family of nucleocytoplasmic, large, double-stranded DNA viruses with extremely complex genomes.
Biguanides
DNA, Protozoan
Deoxyribonucleic acid that makes up the genetic material of protozoa.
Keratitis
Inflammation of the cornea.
Central Nervous System Protozoal Infections
Infections of the brain, spinal cord, or meninges by single celled organisms of the former subkingdom known as protozoa. The central nervous system may be the primary or secondary site of protozoal infection. These diseases may occur as OPPORTUNISTIC INFECTIONS or arise in immunocompetent hosts.
Contact Lenses, Hydrophilic
Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.
Profilins
A family of low molecular weight proteins that bind ACTIN and control actin polymerization. They are found in eukaryotes and are ubiquitously expressed.
Chlamydiales
An order of obligately intracellular, gram-negative bacteria that have the chlamydia-like developmental cycle of replication. This is a two-stage cycle that includes a metabolically inactive infectious form, and a vegetative form that replicates by binary fission. Members of Chlamydiales are disseminated by aerosol or by contact. There are at least six recognized families: CHLAMYDIACEAE, Criblamydiaceae, Parachlamydiaceae, Rhabdochlamydia, Simkaniaceae, and Waddliaceae.
Disinfectants
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Myosins
A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.
Cornea
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)
Ca(2+) Mg(2+)-ATPase
Hartmannella
A genus of free-living amoebae found in fresh water. The cysts usually pass harmlessly through the intestinal tract of man and may thus be found in feces. Occasionally, these organisms cause respiratory tract infections or generalized fatal meningoencephalitis.
Protozoan Proteins
Proteins found in any species of protozoan.
Legionella pneumophila
A species of gram-negative, aerobic bacteria that is the causative agent of LEGIONNAIRES' DISEASE. It has been isolated from numerous environmental sites as well as from human lung tissue, respiratory secretions, and blood.
Antiprotozoal Agents
Substances that are destructive to protozoans.
Benzamidines
Amidines substituted with a benzene group. Benzamidine and its derivatives are known as peptidase inhibitors.
Contractile Proteins
Proteins which participate in contractile processes. They include MUSCLE PROTEINS as well as those found in other cells and tissues. In the latter, these proteins participate in localized contractile events in the cytoplasm, in motile activity, and in cell aggregation phenomena.
RNA, Protozoan
Ribonucleic acid in protozoa having regulatory and catalytic roles as well as involvement in protein synthesis.
Methylmannosides
Mannosides formed by the reaction of the hydroxyl group on the anomeric carbon atom of mannose with methyl alcohol. They include both alpha- and beta-methylmannosides.
Encephalitis
Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
Actins
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
Corneal Ulcer
Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
Methylophilus
A genus of straight or slightly curved gram-negative rods occurring singly or in pairs and isolated from sludge, mud, and river and pond water. (From Bergey's Manual of Determinative Bacteriology, 9th ed)
Disinfection
Rendering pathogens harmless through the use of heat, antiseptics, antibacterial agents, etc.
Meningoencephalitis
An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions.
Chlorhexidine
A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
Spores, Protozoan
A vegetative stage in the life cycle of sporozoan protozoa. It is characteristic of members of the phyla APICOMPLEXA and MICROSPORIDIA.
Encyclopedias as Topic
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)

A novel nucleotide incorporation activity implicated in the editing of mitochondrial transfer RNAs in Acanthamoeba castellanii. (1/587)

In Acanthamoeba castellanii, most of the mtDNA-encoded tRNAs are edited by a process that replaces one or more of the first three nucleotides at their 5' ends. As a result, base pairing potential is restored at acceptor stem positions (1:72, 2:71, and/or 3:70, in standard tRNA nomenclature) that are mismatched according to the corresponding tRNA gene sequence. Here we describe a novel nucleotide incorporation activity, partially purified from A. castellanii mitochondria, that has properties implicating it in mitochondrial tRNA editing in this organism. This activity is able to replace nucleotides at the first three positions of a tRNA (positions 1, 2, and 3), matching the newly incorporated residues through canonical base pairing to the respective partner nucleotide in the 3' half of the acceptor stem. Labeling experiments with natural (Escherichia coli tRNATyr) and synthetic (run-off transcripts corresponding to A. castellanii mitochondrial tRNALeu1) substrates suggest that the nucleotide incorporation activity consists of at least two components, a 5' exonuclease or endonuclease and a template-directed 3'-to-5' nucleotidyltransferase. The nucleotidyltransferase component displays an ATP requirement and generates 5' pppN... termini in vitro. The development of an accurate and efficient in vitro system opens the way for detailed studies of the biochemical properties of this novel activity and its relationship to mitochondrial tRNA editing in A. castellanii. In addition, the system will allow delineation of the structural features in a tRNA that identify it as a substrate for the labeling activity.  (+info)

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex. (2/587)

The Arp2/3 complex, a stable assembly of two actin-related proteins (Arp2 and Arp3) with five other subunits, caps the pointed end of actin filaments and nucleates actin polymerization with low efficiency. WASp and Scar are two similar proteins that bind the p21 subunit of the Arp2/3 complex, but their effect on the nucleation activity of the complex was not known. We report that full-length, recombinant human Scar protein, as well as N-terminally truncated Scar proteins, enhance nucleation by the Arp2/3 complex. By themselves, these proteins either have no effect or inhibit actin polymerization. The actin monomer-binding W domain and the p21-binding A domain from the C terminus of Scar are both required to activate Arp2/3 complex. A proline-rich domain in the middle of Scar enhances the activity of the W and A domains. Preincubating Scar and Arp2/3 complex with actin filaments overcomes the initial lag in polymerization, suggesting that efficient nucleation by the Arp2/3 complex requires assembly on the side of a preexisting filament-a dendritic nucleation mechanism. The Arp2/3 complex with full-length Scar, Scar containing P, W, and A domains, or Scar containing W and A domains overcomes inhibition of nucleation by the actin monomer-binding protein profilin, giving active nucleation over a low background of spontaneous nucleation. These results show that Scar and, likely, related proteins, such as the Cdc42 targets WASp and N-WASp, are endogenous activators of actin polymerization by the Arp2/3 complex.  (+info)

In vivo tandem scanning confocal microscopy in acanthamoeba keratitis. (3/587)

The in vivo confocal microscopy technique provides us with a real-time, non-invasive way of examining the human cornea. The most important advantage of this type of microscopy is to reveal the etiologic agents in infectious keratitis such as Acanthamoeba keratitis. We present several representative cases of Acanthamoeba keratitis, which were diagnosed in their early stages using in vivo confocal microscopy and managed based on that diagnosis. In our Acanthamoeba keratitis cases, highly-reflective round or ovoid organisms with a diameter of about 10-25 um were visualized distinctly against relatively-dark normal parenchymal structures, such as epithelial cells or keratocyte nuclei. Double-walled structures of Acanthamoeba cysts were clearly demonstrated in some cases. We can confirm that in vivo tandem scanning confocal microscopy is a powerful diagnostic tool for identifying the infecting organisms in Acanthamoeba keratitis.  (+info)

Serum antibodies to Balamuthia mandrillaris, a free-living amoeba recently demonstrated to cause granulomatous amoebic encephalitis. (4/587)

Free-living amoebae cause three well-defined disease entities: a rapidly fatal primary meningoencephalitis, a chronic granulomatous amoebic encephalitis (GAE), and a chronic amoebic keratitis. GAE occurs in immunocompromised persons. Recently, another type of free-living amoeba, Balamuthia mandrillaris, has been shown to cause GAE. The finding that this amoeba has caused infection in some healthy children has raised the possibility that humans may lack immunity to B. mandrillaris. Human serum was examined for the presence of surface antibodies specific for this amoeba by immunofluorescence. Sera from adults contained titers of 1/64-1/256 of anti-B. mandrillaris antibodies (IgM and IgG classes), which did not cross-react with other amoebae. Cord blood contained very low antibody levels, but levels similar to those in adults were seen in serum of 1- to 5-year-old children.  (+info)

Legionella pneumophila utilizes the same genes to multiply within Acanthamoeba castellanii and human macrophages. (5/587)

In previous reports we described a 22-kb Legionella pneumophila chromosomal locus containing 18 genes. Thirteen of these genes (icmT, -R, -Q, -P, -O, -M, -L, -K, -E, -C, -D, -J, and -B) were found to be completely required for intracellular growth and killing of human macrophages. Three genes (icmS, -G, and -F) were found to be partially required, and two genes (lphA and tphA) were found to be dispensable for intracellular growth and killing of human macrophages. Here, we analyzed the requirement of these genes for intracellular growth in the protozoan host Acanthamoeba castellanii, a well-established important environmental host of L. pneumophila. We found that all the genes that are completely required for intracellular growth in human macrophages are also completely required for intracellular growth in A. castellanii. However, the genes that are partially required for intracellular growth in human macrophages are completely required for intracellular growth in A. castellanii. In addition, the lphA gene, which was shown to be dispensable for intracellular growth in human macrophages, is partially required for intracellular growth in A. castellanii. Our results indicate that L. pneumophila utilizes the same genes to grow intracellularly in both human macrophages and amoebae.  (+info)

Rho-family GTPases require the Arp2/3 complex to stimulate actin polymerization in Acanthamoeba extracts. (6/587)

BACKGROUND: Actin filaments polymerize in vivo primarily from their fast-growing barbed ends. In cells and extracts, GTPgammaS and Rho-family GTPases, including Cdc42, stimulate barbed-end actin polymerization; however, the mechanism responsible for the initiation of polymerization is unknown. There are three formal possibilities for how free barbed ends may be generated in response to cellular signals: uncapping of existing filaments; severing of existing filaments; or de novo nucleation. The Arp2/3 complex localizes to regions of dynamic actin polymerization, including the leading edges of motile cells and motile actin patches in yeast, and in vitro it nucleates the formation of actin filaments with free barbed ends. Here, we investigated actin polymerization in soluble extracts of Acanthamoeba. RESULTS: Addition of actin filaments with free barbed ends to Acanthamoeba extracts is sufficient to induce polymerization of endogenous actin. Addition of activated Cdc42 or activation of Rho-family GTPases in these extracts by the non-hydrolyzable GTP analog GTPgammaS stimulated barbed-end polymerization, whereas immunodepletion of Arp2 or sequestration of Arp2 using solution-binding antibodies blocked Rho-family GTPase-induced actin polymerization. CONCLUSIONS: For this system, we conclude that the accessibility of free barbed ends regulates actin polymerization, that Rho-family GTPases stimulate polymerization catalytically by de novo nucleation of free barbed ends and that the primary nucleation factor in this pathway is the Arp2/3 complex.  (+info)

Mechanism of interaction of Acanthamoeba actophorin (ADF/Cofilin) with actin filaments. (7/587)

We characterized the interaction of Acanthamoeba actophorin, a member of ADF/cofilin family, with filaments of amoeba and rabbit skeletal muscle actin. The affinity is about 10 times higher for muscle actin filaments (Kd = 0.5 microM) than amoeba actin filaments (Kd = 5 microM) even though the affinity for muscle and amoeba Mg-ADP-actin monomers (Kd = 0.1 microM) is the same (Blanchoin, L., and Pollard, T. D. (1998) J. Biol. Chem. 273, 25106-25111). Actophorin binds slowly (k+ = 0.03 microM-1 s-1) to and dissociates from amoeba actin filaments in a simple bimolecular reaction, but binding to muscle actin filaments is cooperative. Actophorin severs filaments in a concentration-dependent fashion. Phosphate or BeF3 bound to ADP-actin filaments inhibit actophorin binding. Actophorin increases the rate of phosphate release from actin filaments more than 10-fold. The time course of the interaction of actophorin with filaments measured by quenching of the fluorescence of pyrenyl-actin or fluorescence anisotropy of rhodamine-actophorin is complicated, because severing, depolymerization, and repolymerization follows binding. The 50-fold higher affinity of actophorin for Mg-ADP-actin monomers (Kd = 0.1 microM) than ADP-actin filaments provides the thermodynamic basis for driving disassembly of filaments that have hydrolyzed ATP and dissociated gamma-phosphate.  (+info)

Legionella pneumophila contains a type II general secretion pathway required for growth in amoebae as well as for secretion of the Msp protease. (8/587)

We report the identification of a set of Legionella pneumophila genes that encode products with homology to proteins of the type II general secretion pathway of gram-negative bacteria. A strain containing a deletion-substitution mutation of two of these genes was unable to secrete the Msp protease. This strain was unable to multiply within the free-living amoeba Acanthamoeba castellanii yet was able to kill HL-60-derived macrophages. Because Msp is not required for growth in amoebae, other proteins which are important for growth in amoebae are likely secreted by this pathway.  (+info)

Detection of Bacterial Endosymbionts in Clinical Acanthamoeba Isolates<...
TY - JOUR. T1 - Detection of Bacterial Endosymbionts in Clinical Acanthamoeba Isolates. AU - Iovieno, Alfonso. AU - Ledee, Dolena R.. AU - Miller, Darlene. AU - Alfonso, Eduardo C. PY - 2010/3/1. Y1 - 2010/3/1. N2 - Purpose: To determine the presence of 4 clinically relevant bacterial endosymbionts in Acanthamoeba isolates obtained from patients with Acanthamoeba keratitis (AK) and the possible contribution of endosymbionts to the pathogenesis of AK. Design: Experimental study. Participants: Acanthamoeba isolates (N = 37) recovered from the cornea and contact lens paraphernalia of 23 patients with culture-proven AK and 1 environmental isolate. Methods: Acanthamoeba isolates were evaluated for the presence of microbial endosymbionts belonging to the bacterial genera Legionella, Pseudomonas, Mycobacterium, and Chlamydia using molecular techniques (polymerase chain reaction and sequence analysis, fluorescence in situ hybridization) and transmission electron microscopy. Corneal toxicity and ...
https://miami.pure.elsevier.com/en/publications/detection-of-bacterial-endosymbionts-in-clinical-acanthamoeba-iso
Genetic diversity among Acanthamoeba sp. isolated from clinically suspected cases of Amoebic keratitis patients attending a...Genetic diversity among Acanthamoeba sp. isolated from clinically suspected cases of Amoebic keratitis patients attending a...
Purpose: To detect the genotypes of Acanthamoeba spp. isolates from patients of clinically suspected amoebic keratitis and proteomic characterisation of trophozoite and cyst stages. Methods: Corneal scrapings from clinically suspected amoebic keratitis(AK) patients (107) attending our tertiary care hospital during last 2 years were subjected to culture on 2% non- nutrient agar plates overlaid with E.coli. DNA isolation followed by PCR assay was performed for amplification of DF3 region (280bp) of 18S rRNA gene of Acanthamoeba spp.. PCR products were sequenced and aligned using software CLUSTAL W. Phylogenetic tree reconstructions was performed with phylogenetic computer program MEGA4 using neighbour-joining method as well as UPGMA anakysis. The cultured trophozoites were encysted in laboratory conditions and the whole cell lysates of both the stages were subjected to SDS-PAGE and two dimensional gel electrophoresis.. Results: Acanthamoeba spp. was isolated from 18 of the 107 (16.82%)suspected ...
http://iovs.arvojournals.org/article.aspx?articleid=2151695
Acanthamoeba Infection Market Innovative Treatments, Key Methodologies, Top Players Success Milestones and Application...Acanthamoeba Infection Market Innovative Treatments, Key Methodologies, Top Players Success Milestones and Application...
The recent study, Acanthamoeba Infection market forecasts the business performance of the Acanthamoeba Infection market for the forecast period, 2019 to 2026. The study considers the estimated period as the base duration and brings to light the important information associated with the market size, share and growth rate of the Acanthamoeba Infection market.. Apart from this, the research closely examines the market share occupied by some of the prominent market players in the Acanthamoeba Infection market for the forecast period, 2019 to 2026. Researchers behind the research unmask vital statistics on market segmentation including product types, application, sale and geography.. FREE SAMPLE COPY [Customized Copy + CAGR and Gross Market Value Included] @ https://www.marketexpertz.com/sample-enquiry-form/74658. This study relies on the evolution of the industry to derive the trends that are observed. A significant increase in the global market is visible, which promises the expansion of the market ...
http://themarketstrategies.com/acanthamoeba-infection-market-innovative-treatments-key-methodologies-top-players-success-milestones-and-application-forecasts-to-2026/
Campylobacter jejuni Actively Invades the Amoeba Acanthamoeba polyphaga and Survives within Non Digestive VacuolesCampylobacter jejuni Actively Invades the Amoeba Acanthamoeba polyphaga and Survives within Non Digestive Vacuoles
The Gram-negative bacterium Campylobacter jejuni is able to enter, survive and multiply within the free living amoeba Acanthamoeba polyphaga, but the molecular mechanisms behind these events are still unclear. We have studied the uptake and intracellular trafficking of viable and heat killed bacterial cells of the C. jejuni strain 81-176 in A. polyphaga. We found that viable bacteria associated with a substantially higher proportion of Acanthamoeba trophozoites than heat killed bacteria. Furthermore, the kinetics of internalization, the total number of internalized bacteria as well as the intracellular localization of internalized C. jejuni were dramatically influenced by bacterial viability. Viable bacteria were internalized at a high rate already after 1 h of co-incubation and were observed in small vacuoles tightly surrounding the bacteria. In contrast, internalization of heat killed C. jejuni was low at early time points and did not peak until 96 h. These cells were gathered in large ...
http://www.diva-portal.org/smash/record.jsf?pid=diva2:677424
Microbiology Society Journals | The potential pathogenicity of chlorhexidine-sensitive Acanthamoeba strains isolated from...Microbiology Society Journals | The potential pathogenicity of chlorhexidine-sensitive Acanthamoeba strains isolated from...
Pathogenic strains of the genus Acanthamoeba are causative agents of a serious sight-threatening infection of the eye known as Acanthamoeba keratitis. The prevalence of this infection has risen in the past 20 years, mainly due to the increase in number of contact lens wearers. In this study, the prevalence of Acanthamoeba in a risk group constituted by asymptomatic contact lens wearers from Tenerife, Canary Islands, Spain, was evaluated. Contact lenses and contact lens cases were analysed for the presence of Acanthamoeba isolates. The isolates' genotypes were also determined after rDNA sequencing. The pathogenic potential of the isolated strains was subsequently established using previously described molecular and biochemical assays, which allowed the selection of three strains with high pathogenic potential. Furthermore, the sensitivity of these isolates against two standard drugs, ciprofloxacin and chlorhexidine, was analysed. As the three selected strains were sensitive to chlorhexidine, its
http://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.2008/003459-0
Parasite of the Day: Acanthamoeba spp.Parasite of the Day: Acanthamoeba spp.
Acanthamoeba spp. are microscopic organisms that can be found just about anywhere, from soil to water, to the air we breathe. They are the direct culprits of Acanthamoeba keratitis (AK) a relatively rare but sight-threatening disease which is actually caused by at least eight species of Acanthamoeba: A. castellanii, A. culbertsoni, A. polyphaga, A. hatchetti, A. rhysodes, A. lugdunesis, A. quina, and A. griffin. Ocular trauma and contaminated water are also associated with AK infections but it has been found that contact lens wearing accounts for , 80% of the cases. If found early the infection can be cured, but this gets progressively more difficult the longer it remains untreated. The difficulty lies with the life cycle of the Acanthamoeba species which consists of two stages: the trophozoite and the cyst ...
http://dailyparasite.blogspot.com/2019/02/acanthamoeba-spp.html
Interactions of some common pathogenic bacteria with<i> Acanthamoeba polyphaga<...
TY - JOUR. T1 - Interactions of some common pathogenic bacteria with Acanthamoeba polyphaga. AU - Huws, Sharon A.. AU - Morley, Robert J.. AU - Jones, Martin V.. AU - Brown, Michael R. W.. AU - Smith, Anthony W.. N1 - ID number: ISI:000255137900016. PY - 2008. Y1 - 2008. N2 - Protozoan grazing is a major trophic pathway whereby the biomass re-enters the food web. Nonetheless, not all bacteria are digested by protozoa and the number known to evade digestion, resulting in their environmental augmentation, is increasing. We investigated the interactions of Bacillus cereus, Enterococcus faecalis, Enteropathogenic Escherichia coli (EPEC), Listeria monocytogenes, Salmonella enterica serovar Typhimurium, and methicillin-sensitive Staphylococcus aureus (MSSA), with the amoeba, Acanthamoeba polyphaga. There was evidence of predation of all bacterial species except L. monocytogenes and S. aureus, where extracellular numbers were significantly higher when cultured with amoebae compared with growth in the ...
https://researchportal.bath.ac.uk/en/publications/interactions-of-some-common-pathogenic-bacteria-withi-acanthamoeb
Acanthamoeba - WikipediaAcanthamoeba - Wikipedia
Acanthamoeba is a genus of amoebae, a single-celled eukaryote commonly recovered from soil, fresh water and other habitats. Acanthamoeba has two evolutive forms, the metabolically active trophozoite and a dormant, stress resistant cyst. Trophozoites are small, usually 15 to 35 μm in length and amoeboid in shape. In nature, Acanthamoeba species are free-living bacterivores, but in certain situations they can cause infections (Acanthamebiasis) in humans and other animals. Acanthamoeba spp. are among the most prevalent protozoa found in the environment. They are distributed worldwide, and have been isolated from soil, air, sewage, seawater, chlorinated swimming pools, domestic tap water, bottled water, dental treatment units, hospitals, air-conditioning units, and contact lens cases. Additionally, Acanthamoeba have been isolated from human skin, nasal cavities, throats, and intestines, as well as plants and other mammals. Diseases caused by Acanthamoeba include keratitis and granulomatous amoebic ...
https://en.wikipedia.org/wiki/Acanthamoeba
Calcium enhances Acanthamoeba polyphaga binding to extracellular matrix proteins. | IOVS | ARVO JournalsCalcium enhances Acanthamoeba polyphaga binding to extracellular matrix proteins. | IOVS | ARVO Journals
PURPOSE: To characterize better the ameba-host interactions that may be involved with the pathogenesis of Acanthamoeba keratitis, the role of calcium (Ca2+) on the binding of Acanthamoeba polyphaga to extracellular matrix proteins was examined in vitro. METHODS: The binding of a metabolically labeled A. polyphaga (CDC:0187:1) isolate from a case of human keratitis to collagen type IV, laminin, and fibronectin was assessed through a range of calcium concentrations in the external fluid. Binding to collagen IV was studied in detail, with and without other divalent cations and calcium channel modulators. RESULTS: Calcium increased binding in a dose-dependent manner, with significant effects at 0.1 to 1.0 microM and near-maximal effects at 1 to 100 microM, depending upon the matrix protein. Magnesium alone had no effect on ameba binding to collagen IV but suppressed the action of calcium. Strontium enhanced ameba binding, with maximal effect at 100 microM. The calcium channel antagonists nifedipine ...
http://iovs.arvojournals.org/article.aspx?articleid=2160943
Acanthamoeba Infection: Evaluation
Another name for Acanthamoeba Infection is Acanthamoeba Infection. The evaluation of an acanthamoeba infection begins with a history and physical examination ...
http://www.freemd.com/acanthamoeba-infection/evaluation.htm
Structure and polymerization of Acanthamoeba myosin-II filaments. | Journal of Cell Biology | Rockefeller University PressStructure and polymerization of Acanthamoeba myosin-II filaments. | Journal of Cell Biology | Rockefeller University Press
Acanthamoeba myosin-II forms filaments of two different sizes. Thin bipolar filaments 7 nm wide and 200 nm long consist of 16 myosin-II molecules. Thick bipolar filaments of variable width (14-19 nm) consist of 40 or more myosin-II molecules. Both have a central bare zone 90 nm long and myosin heads projecting laterally at the ends. The heads are arranged in rows spaced 15 nm apart. In the case of the thin myosin-II filaments there are two molecules per row. The thick filaments are formed rapidly and reversibly in the presence of 6-10 mM MgCl2 (or any of five other different divalent cations tested) by the lateral aggregation of thin myosin-II filaments. Acid pH also favors thick filament formation. Neither the myosin-II concentration (50-1,000 micrograms/ml) nor ATP has an effect on the morphology of the filaments. The polymerization mechanism was studied quantitatively by measuring the amount of polymer formed (Cp) under various conditions as a function of total myosin-II concentration (Ct). ...
https://rupress.org/jcb/article/95/3/816/56632/Structure-and-polymerization-of-Acanthamoeba
Avaliação fisiológica, morfológica e caracterização imunoquímica de Acanthamoeba por anticorpos policlonais e monoclonaisAvaliação fisiológica, morfológica e caracterização imunoquímica de Acanthamoeba por anticorpos policlonais e monoclonais
Abstract: The free-living amoebae of the genus Acanthamoeba are widely distributed in nature and are considered potentially pathogenic organisms. Occasionally they can trigger human infections such as granulomatous amoebic encephalitis and amoebic keratitis. The investigation of differentiating characteristics between pathogenic strains and those not associated with infection may help to determine factors related to pathogenicity and the development of diagnostic tests. In this sense, the aim of this study was to perform a comparative evaluation; by means of physiological, morphological and immunochemical criteria; between clinical and environmental samples of Acanthamoeba. Trophozoites of four isolates were used: a clinical sample, obtained from a confirmed case of amoebic keratitis; an environmental sample, obtained from the dust of the residence of the same patient; and two reference samples A. poliphaga #2, obtained from an amoebic keratitis (ATCC 30641) and A. poliphaga #4, obtained from ...
https://acervodigital.ufpr.br/handle/1884/46495
Acanthamoeba sp. ATCC ® PRA-219™Acanthamoeba sp. ATCC ® PRA-219™
Acanthamoeba sp. ATCC ® PRA-219™ Designation: UWC1/UV-7 Isolation: Acanthamoeba sp. UWC1 coincubated with activated sludge. Plattling, Bavaria, Germany.
https://www.atcc.org/Products/Cells_and_Microorganisms/Protozoa/Protozoa_Alphanumeric/PRA-219.aspx
Drug target identification, validation, characterisation and exploitation for treatment of Acanthamoeba (species) infections<...Drug target identification, validation, characterisation and exploitation for treatment of Acanthamoeba (species) infections<...
TY - JOUR. T1 - Drug target identification, validation, characterisation and exploitation for treatment of Acanthamoeba (species) infections. AU - Roberts, Craig W.. AU - Henriquez, Fiona L.. N1 - Special Issue - Biology and Pathogenecity of Free-Living Amoebae. Compiled after the XIIIth International Meeting on the Biology and Pathogenicity of Free-Living Amoebae, FLAM 2009, Tenerife, Spain. PY - 2010/9. Y1 - 2010/9. N2 - New more efficacious antimicrobials as required for the treatment of Acanthamoeba infections as those currently available require arduous treatment regimes, are not always effective and are poorly active against the cystic stages. Herein, we review potential drug targets including tubulin, alternative oxidase, amino acid biosynthesis and myosin. In addition, we review the literature for current missing tools and resources for the identification, validation and development of new antimicrobials for this organism. Additional targets should come to light through a concerted ...
https://pureportal.strath.ac.uk/en/publications/drug-target-identification-validation-characterisation-and-exploi
Contagious: Acanthamoeba infection of the eye - RightDiagnosis.comContagious: Acanthamoeba infection of the eye - RightDiagnosis.com
Acanthamoeba infection of the eye is it contagious? Contagiousness of Acanthamoeba infection of the eye including infectiousness, transmission, and contagion methods and vectors.
http://www.rightdiagnosis.com/a/acanthamoeba_infection_of_the_eye/contagious.htm
Efficacy of anti-neoplastic drugs against acanthamoeba<...Efficacy of anti-neoplastic drugs against acanthamoeba<...
TY - JOUR. T1 - Efficacy of anti-neoplastic drugs against acanthamoeba. AU - Beattie, T.K.. AU - Tomlinson, A.. AU - Seal, D.. PY - 2003. Y1 - 2003. N2 - Purpose:Late presenting cases of Acanthamoeba keratitis are particularly difficult to treat. The organism can persist, despite treatment with chlorhexidine or PHMB, maintaining an active infection. New drug therapies with enhanced activity are therefore needed to treat this painful, potentially blinding infection. This study was undertaken to determine the efficacy of three anti-cancer drugs against Acanthamoeba. Methods:Doubling dilutions of MGBG [10-0.15mg/ml (38.5-0.6mM)], CHS 828 [660-10µg/ml (1782-27µM)] and hexadecyl-phosphocholine [HePC, Miltefosine; 660-10µg/ml (1782-27µM)] were tested alone or in combination with chlorhexidine, PHMB and propamidine, for efficacy against Acanthamoeba castellanii trophozoites or cysts. Sensitivity assays were performed over 48h in 96-well microtitre plates. Results: MGBG killed trophozoites at ...
https://pureportal.strath.ac.uk/en/publications/efficacy-of-anti-neoplastic-drugs-against-acanthamoeba
New tool for the simultaneous detection of ten genotypes of Acanthamoeba | British Journal of OphthalmologyNew tool for the simultaneous detection of ten genotypes of Acanthamoeba | British Journal of Ophthalmology
New tool for the simultaneous detection of ten different genotypes of Acanthamoeba available from the American Type Culture Collection. Background: Acanthamoeba keratitis (AK) is a sight-threatening infection and none of the current diagnosis tests are able to detect in one reaction low levels of the vast majority of strains associated with pathology. The goal of this work was to validate a new tool for the detection of the American Type Cell Collection referenced Acanthamoeba monitoring simultaneously DNA extraction yields and PCR inhibitors. Performances were assessed on corneal scrapings.. Methods: Primers were selected in a region bracketing a 41591 bp of the A. castellanii mitochondrion gene. DNA extraction and PCR inhibitors were monitored by adding an internal control (virus). Acanthamoeba were detected and quantified by the real time fast duplex TaqMan® PCR (f-d-real-t PCR) and negativity confirmed by SYBR Green real time PCR.. Results: The f-d-real-t PCR detects 0.1 cyst/µl or less of ...
http://bjo.bmj.com/content/early/2009/04/28/bjo.2008.144873
Meňavky rodu Acanthamoeba - pôvodcovia infekcií človeka | proLékaře.czMeňavky rodu Acanthamoeba - pôvodcovia infekcií človeka | proLékaře.cz
1. Adl, S. M., Simpson, A. G. B., Farmer, M. A., Andersen, R. A. et al. The new higher level classification of eukaryotes with emphasis on the taxonomy of protists. J. Eukaryot. Microbiol., 2005, 52, p. 399-451. 2. Aichelburg, A. C., Walochnik, J., Assadian, O., Prosch, H. et al. Successful treatment of disseminated Acanthamoeba sp. infection with miltefosine. Emerg. Infect. Dis., 2008, 14, p. 1743-1746. 3. Booton, G. C., Visvesvara, G. S., Byers, T. J., Kelly, D. J. et al. Identification and distribution of Acanthamoeba species genotypes associated with nonkeratitis infections. J. Clin. Microbiol., 2005, 43, p. 1689-693. 4. Cengiz, A. M., Harmis, N., Stapleton, F. Co-incubation of Acanthamoeba castellanii with strains of Pseudomonas aeruginosa alters the survival of amoeba. Clin. Exp. Ophthalmol., 2000, 28, p. 191-193. 5. Chatton, E. Classe des Lobosa Leidy, 1879. Ordre des amoebiens nus ou Amoebaea. In Grassé, P. P. Traité de zoologie, anatomie, systématique, biologie. Tome I. Protozoaires. ...
https://www.prolekare.cz/casopisy/epidemiologie/2011-3/menavky-rodu-acanthamoeba-povodcovia-infekcii-cloveka-36183
Acanthamoeba: A rare and potentially blinding parasite - Outbreak News TodayAcanthamoeba: A rare and potentially blinding parasite - Outbreak News Today
There are three main genera of free living amoeba that infect humans - Acanthamoeba, Balamuthia, Naegleria that are are important causes of disease in humans and animals. The topic for todays podcast will be one of them- Acanthamoeba.. Acanthamoeba is a microscopic, free-living amoeba that can cause rare, but severe infections of the eye, skin, and central nervous system.. Joining me to talk about Acanthamoeba is Parasitology teacher and author of Parasites: Tales of Humanitys Most Unwelcome Guests, Rosemary Drisdelle.. ...
http://outbreaknewstoday.com/acanthamoeba-rare-potentially-blinding-parasite-47485/
Genotyping determination of Acanthamoeba strains: an original study and a systematic review in Iran.Genotyping determination of Acanthamoeba strains: an original study and a systematic review in Iran.
This study aimed to detect the presence of Acanthamoeba spp. in different water resources of Zahedan, southeast of Iran, and also systematically reviewed all publications regarding Acanthamoeba in Iran (2005-2018). Fifty water samples were collected from different water resources in Zahedan. The positive samples were identified morphologically and subjected to polymerase chain reaction (PCR) using...
https://medworm.com/737716640/genotyping-determination-of-acanthamoeba-strains-an-original-study-and-a-systematic-review-in-iran/
Possible environmental sources of Acanthamoeba spp in contact lens wearers. | British Journal of OphthalmologyPossible environmental sources of Acanthamoeba spp in contact lens wearers. | British Journal of Ophthalmology
The water supply and dust samples from the home environment (bathrooms and kitchens) of 50 wearers of contact lenses (CLs) were cultured for the presence of free-living amoebae. CL cases, solutions, and water taps were cultured for bacteria, which amoebae require for growth. Acanthamoeba spp were isolated from water drawn from six bathroom cold water taps (tank supplied), five in the presence of limescale, and from one kitchen cold water tap (mains supplied). There was an association between the presence of limescale in water and direct culture for free-living amoebae, suggesting that scale provides a favourable microenvironment for amoebae. Acanthamoebae were also found in dust from around one washbasin. Nineteen of 50 CL cases, 12/122 CL care rinsing solutions, and 59/100 cold water taps yielded Gram negative bacteria which could be ingested by amoebae. It is concluded from this study that CLs should not be washed in first-drawn tank-fed cold water, especially if limescale is present, and that ...
http://bjo.bmj.com/content/76/7/424
Acanthamoeba Infections | Quick Medical Diagnosis & Treatment 2021 | AccessMedicine | McGraw-Hill MedicalAcanthamoeba Infections | Quick Medical Diagnosis & Treatment 2021 | AccessMedicine | McGraw-Hill Medical
Acanthamoeba Infections. In: Papadakis MA, McPhee SJ, Bernstein J. Papadakis M.A., & McPhee S.J., & Bernstein J(Eds.),Eds. Maxine A. Papadakis, et al.eds. Quick Medical Diagnosis & Treatment 2021. McGraw-Hill; Accessed November 26, 2020. https://accessmedicine.mhmedical.com/content.aspx?bookid=2986§ionid=251085632 ...
https://accessmedicine.mhmedical.com/content.aspx?bookid=2986§ionid=251085632&TopLevelContentDisplayName=Quick%20Reference
Changes in the immune system in experimental acanthamoebiasis in immunocompetent and immunosuppressed hosts | Parasites &...Changes in the immune system in experimental acanthamoebiasis in immunocompetent and immunosuppressed hosts | Parasites &...
Acanthamoebiasis is most often found in patients with immune deficiency, with infections facilitated by the intake of immunosuppressive drugs. The host immune response to Acanthamoeba spp. infection is poorly understood. Thus, in this study, we aimed to examine the course of Acanthamoeba spp. infection taking into account the hosts immunological status, including assessment of the hematological parameters, cytokine analysis, immunophenotypic changes in spleen populations, and histological spleen changes, which could help clarify some aspects of the immune response to acanthamoebiasis. In our experimental study, we used Acanthamoeba strain AM 22 isolated from the bronchoaspirate of a patient with acute myeloid leukaemia (AML) and atypical pneumonia symptoms. Acanthamoeba spp. affected the hematological parameters in immunocompetent and immunosuppressed mice and induced a change in spleen weight during infection. Moreover, analysis of anti-inflammatory (IL-4 and IL-10) and pro-inflammatory (IL-17A and
https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-018-3108-x/tables/1
Acanthamoeba hatchetti Sawyer et al. ATCC ® PRA-114™Acanthamoeba hatchetti Sawyer et al. ATCC ® PRA-114™
Acanthamoeba hatchetti ATCC ® PRA-114™ Designation: 3ST Isolation: clinical specimen - human Vienna Austria Isolation date: 1997
https://www.atcc.org/en/Products/Cells_and_Microorganisms/Protozoa/Parasitic_Protozoa/PRA-114.aspx
Interactions of the ubiquitous amoeba Acanthamoeba polyphaga with a plethora of pathogenic bacteria - Queens University...
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https://pure.qub.ac.uk/en/activities/interactions-of-the-ubiquitous-amoeba-acanthamoeba-polyphaga-with
Phosphorylation of Acanthamoeba actophorin (ADF/cofilin) blocks interaction with actin without a change in atomic structure<...
TY - JOUR. T1 - Phosphorylation of Acanthamoeba actophorin (ADF/cofilin) blocks interaction with actin without a change in atomic structure. AU - Blanchoin, Laurent. AU - Robinson, Robert C.. AU - Choe, Senyon. AU - Pollard, Thomas D.. N1 - Funding Information: We thank members of the Pollard laboratory for technical assistance, advice and helpful discussion. L.B. is extremely grateful to D. Kaiser for his help with isoelectric focusing. We thank David C. Edwards and Gordon N. Gill for the phosphorylation of actophorin by LIM-kinase, Gary M. Bokoch for GST-Pak 1, Wolfgang H. Fischer and Chris Park for protein sequencing and James Bamburg for his advice in the dephosphorylation experiment. This work was supported by NIH grant GM 26338 to T.D.P.. PY - 2000/1/14. Y1 - 2000/1/14. N2 - LIM-kinase activated by GST-Pak1 phosphorylates Acanthamoeba actophorin stoichiometrically and specifically on serine 1. The atomic structure of phosphorylated actophorin determined by X-ray crystallography is ...
https://okayama.pure.elsevier.com/en/publications/phosphorylation-of-acanthamoeba-actophorin-adfcofilin-blocks-inte
Development and validation of a real-time PCR assay for the detection of clinical acanthamoebae | BMC Research Notes | Full TextDevelopment and validation of a real-time PCR assay for the detection of clinical acanthamoebae | BMC Research Notes | Full Text
Suboptimal agreement between molecular assays for the detection of Acanthamoeba spp. in clinical specimens has been demonstrated, and poor assay sensitivity directly imperils the vision of those affected by amoebic keratitis (AK) through delayed diagnosis. We sought to develop and validate a single Taqman real time PCR assay targeting the Acanthamoeba 18S rRNA gene that could be used to enhance sensitivity and specificity when paired with reference assays. Biobanked DNA from surplus delinked AK clinical specimens and 10 ATCC strains of Acanthamoeba was extracted. Sequence alignment of 66 18S rRNA regions from 12 species of Acanthamoeba known to cause keratitis informed design of a new TaqMan primer set. Performance of the new assay was compared to the 2 assays used currently in our laboratory. Among 24 Acanthamoeba-positive and 83 negative specimens by the CDC reference standard, performance characteristics of the newly designed primer set were as follows: sensitivity 100%, specificity 94%, PPV 82.8%,
https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-017-2666-x/tables/4
ما هي الاكانثاميبا Acanthamoeba|اسبابها|الاعراض|العلاج | Medicine, science and more
تعالى نفصصهم تاني … المرض الأول اسمه Acanthamoeba keratitis: وده بيعمل التهاب في قرنيه العين وده عامل كانه سدلك العدسة اللى بتصور بيها يعنى ممكن يسبب العمى.. المرض التاني Granulomatous Amebic Encephalitis: وده بيعمل التهاب في المخ والحبل الشوكي وده معناه انه ممكن يقتل رئيس دولتك يعنى يموت المخ والحبل الشوكي وده معناه انهيار الدولة كلها يعنى يؤدي للموت. المرض التالت واسمه disseminated infection: وده ذي ما قولنا عامل ذي الغزو بينتشر في كل حتة وبيعمل التهابات في كل حتة.. You can say This means that it is dangerous and can kill me and can attack me at any moment and you told me that this enemy lives everywhere… this is scary.. No, dont worry. It is rare to attack you because it is a weak ...
https://medicine-science-and-more.com/what-is-acanthamoeba-infectioncausessymptomstreatment25/
Acanthamoeba polyphagaAcanthamoeba polyphaga
Virology Highlights features highlighted articles published in Virology, with posts summarizing the research in the authors words.
http://www.virologyhighlights.com/tag/acanthamoeba-polyphaga/
Viscometric analysis of the gelation of Acanthamoeba extracts and purification of two gelation factors. | JCBViscometric analysis of the gelation of Acanthamoeba extracts and purification of two gelation factors. | JCB
We have studied the kinetics of the gelation process that occurs upon warming cold extracts of Acanthamoeba using a low-shear falling ball assay. We find that the reaction has at least two steps, requires 0.5 mM ATP and 1.5 mM MgCl2, and is inhibited by micromolar Ca++. The optimum pH is 7.0 and temperature, 25 degrees-30 degrees C. The rate of the reaction is increased by cold preincubation with both MgCl2 and ATP. Nonhydrolyzable analogues of ATP will not substitute for ATP either in this potentiation reaction or in the gelation process. Either of two purified or any one of four partially purified Acanthamoeba proteins will cross-link purified actin to form a gel, but none can account for the dependence of the reaction in the crude extract on Mg-ATP or its regulation by Ca++. This suggests that the extract contains, in addition to actin-cross-linking proteins, factors dependent on Mg-ATP and Ca++ that regulate the gelation process. ...
http://jcb.rupress.org/content/85/2/414.long
Castellani Paint Colorless effects, treatment Phenol Topical indications symptomsCastellani Paint Colorless effects, treatment Phenol Topical indications symptoms
Learn about Castellani Paint Colorless effects, symptoms, what is, Phenol Topical treatment, mechanism of action and formula. Important information I should know about Castellani Paint Colorless, Phenol Topical effects, symptoms and treatment.
https://www.medslook.com/c/castellani-paint-colorless-phenol-topical/effectstreatmentindicationssymptoms.htm
Acanthamoeba quina | Semantic ScholarAcanthamoeba quina | Semantic Scholar
A species of motile, unicellular eukaryotic amoebae within the family of Acanthamoebidae. A. quina is placed in morphological group II with a 18s rRNA gene sequence type of T4. Members of this group are characterized by the presence of wrinkled ectocysts and endocysts which could be stellate, polygonal, triangular, or oval. This species is a human pathogen and may cause granulomatous amoebic encephalitis and amoebic keratitis.
https://www.semanticscholar.org/topic/Acanthamoeba-quina/1505220
genesig Real-time PCR detection kit for Acanthamoeba species - 150 rea - AFSBio Inc.genesig Real-time PCR detection kit for Acanthamoeba species - 150 rea - AFSBio Inc.
Product features: Exceptional value for money Rapid detection of all clinically relevant subtypes Positive copy number standard curve for quantification Highly specific detection profile High priming efficiency Broad dynamic detection range (>6 logs) Sensitive to < 100 copies of target Accurate controls to confir
https://afsbio.com/products/genesig-real-time-pcr-detection-kit-for-acanthamoeba-species-150-reactions
Acanthamoeba - pathogen and vector of highly pathogenic bacteria strains to healthy and immunocompromised individuals / -...Acanthamoeba - pathogen and vector of highly pathogenic bacteria strains to healthy and immunocompromised individuals / -...
Acanthamoeba - pathogen and vector of highly pathogenic bacteria strains to healthy and immunocompromised individuals / - BAZA PUBLIKACJI PRACOWNIKÓW US
https://publi.bg.szczecin.pl/cgi-bin/koha/opac-detail.pl?bib=66308
Acanthamoeba StainAcanthamoeba Stain
Acanthamoeba Stain,ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories client,medicine,medical supply,medical supplies,medical product
http://www.bio-medicine.org/medicine-products/Acanthamoeba-Stain-20892-1/
SYNLAB En: Acanthamoeba spp RNA, biological sampleSYNLAB En: Acanthamoeba spp RNA, biological sample
Additional information (132) del (1) Delivery time (936) Description (190) Discontinued temporarily (9) Erased test (536) Festivity (4) food intolerance studied (2) Method (362) Modifications (362) New test (770) Notice (10) Reference values (1304) repor (1) Report (31) result format (5) Sample volume (1) Samples (275) Samples Restriction (23) Studied compounds (3) Studied Exons (2) Studied genes (17) Studied genes; (8) Studied genes; Delivery time (15) Studied genes; Description (17) Test modification (1) Test reactivation (3) Units (95) xconfirmar (1) ...
http://blog-en.labconous.com/2019/10/acanthamoeba-spp-rna-biological-sample.html
Castellani successfully can fill Tauzins shoes - Drug Store NewsCastellani successfully can fill Tauzins shoes - Drug Store News
THE NEWS: PhRMA names new president, CEO. For the full story, click here). PhRMAs new president and CEO, John Castellani, doesnt have the political background of Tauzin, former Democratic congressman from Louisiana, but he has something pretty close in the form of a nine-year career as leader of the Business Roundtable, an influential lobbying group of corporate chief executives from various industries.. And it appears PhRMA made a wise choice. Politico quoted an unnamed senior industry official as saying the lobby sought a non-partisan, manager type to head the group while pointing out his relationships with members of Congress in both major parties. David Brennan, head of the organizations search committee and president and CEO of AstraZeneca, pointed out Castellanis experience in coalition building and strong reputation of working across the political divide.. ...
https://www.drugstorenews.com/article/castellani-successfully-can-fill-tauzins-shoes/?ad=insights-and-perspectives
Research Update Issue 23 - IACLEResearch Update Issue 23 - IACLE
The last outbreak of Acanthamoeba infections in US and UK contact lens wearers occurred in the 1990s. In this issue, we include a study that confirms a further outbreak in the UK starting in 2010-2011. Another discusses the challenges faced by the US Food & Drug Administration in developing a standard protocol for disinfection efficacy testing for Acanthamoeba.. Researchers from Canada bring our attention back to hand hygiene and its link to corneal infection and inflammation. A prospective, cross-over study examines the impact of monovision CL correction on reading. And a group of scientists from Spain evaluates light disturbances in children wearing myopia control lenses.. Could early diagnosis of clinical markers of CL discomfort help clinicians set realistic expectations and provide prophylactic management? A team in Australia investigates. And, finally we include a survey that explores current practice in the use of scleral lens therapy.. Happy reading ...
https://iacle.org/research-update-23/
DNA Extraction - Biology-OnlineDNA Extraction - Biology-Online
Hi, I am using QIAamp kit to extract DNA from Acanthamoeba culture. However, I just able to extract about 40ng/ul of concentration only when measured by NanoQuant. Is this concentration normal for Acanthamoeba ? This is because previously extraction from other sample can obtain high concentration up to 300ng/ul. Or is there any pre-treatment required to be done to the sample before using this Qiagen kit? I am sure there is no other step stated in Qiagen handbook, just that any other step that is specifically to acanthamoeba ...
https://www.biology-online.org/biology-forum/viewtopic.php?p=122532
Prevalence of Acanthamoeba from Tap Water in Rio Grande do Sul, BrazilPrevalence of Acanthamoeba from Tap Water in Rio Grande do Sul, Brazil
A free platform for explaining your research in plain language, and managing how you communicate around it - so you can understand how best to increase its impact.
https://www.growkudos.com/publications/10.1007%25252Fs00284-011-0003-5/reader
Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on...Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on...
We identified four polypeptides of 47, 44, 40, and 35 kD that bind to profilin-Sepharose and elute with high salt. When purified by conventional chromatography using an antibody to the 47-kD polypeptide, these four polypeptides copurified as a stoichiometric complex together with three additional polypeptides of 19, 18, and 13 kD that varied in their proportions to the other polypeptides. Partial protein sequences showed that the 47-kD polypeptide is a homologue of S. pombe act2 and the 44-kD polypeptide is a homologue of S. cerevisiae ACT2, both unconventional actins. The 40-kD polypeptide contains a sequence similar to the WD40 motif of the G beta subunit of a trimeric G-protein from Dictyostelium discoideum. From partial sequences, the 35-, 19-, and 18-kD polypeptides appear to be novel proteins. On gel filtration the complex of purified polypeptides cochromatograph with a Stokes radius of 4.8 nm, a value consistent with a globular particle of 220 kD containing one copy of each polypeptide. ...
https://rupress.org/jcb/article/127/1/107/29092/Purification-of-a-cortical-complex-containing-two
Acanthamoeba polyphaga mimivirus - definition of Acanthamoeba polyphaga mimivirus by The Free DictionaryAcanthamoeba polyphaga mimivirus - definition of Acanthamoeba polyphaga mimivirus by The Free Dictionary
Define Acanthamoeba polyphaga mimivirus. Acanthamoeba polyphaga mimivirus synonyms, Acanthamoeba polyphaga mimivirus pronunciation, Acanthamoeba polyphaga mimivirus translation, English dictionary definition of Acanthamoeba polyphaga mimivirus. n. pl. mim·i·vi·rus·es Any of a genus of double-stranded DNA viruses that are the largest of all known viruses. n a very large virus containing DNA
https://www.thefreedictionary.com/Acanthamoeba+polyphaga+mimivirus
Acanthamoeba polyphaga mimivirus Virophage Seroconversion in Travelers Returning from Laos - Volume 18, Number 9-September 2012...
During January 2010, a husband and wife returned from Laos to France with probable parasitic disease. Increased antibodies against an Acanthamoeba polyphaga mimivirus virophage indicated seroconversion. While in Laos, they had eaten raw fish, a potential source of the virophage. This virophage, associated with giant viruses suspected to cause pneumonia, could be an emerging pathogen.
https://wwwnc.cdc.gov/eid/article/18/9/12-0099_article
Diagnosis of Acanthamoeba keratitis in vivo with confocal microscopy. - Semantic ScholarDiagnosis of Acanthamoeba keratitis in vivo with confocal microscopy. - Semantic Scholar
We present eight cases of Acanthamoeba keratitis. In each case; the Acanthamoeba organisms were visualized in the epithelium and anterior stroma using tandem scanning confocal microscopy. The organisms were highly reflective, ovoid, and were 10-25 microns in diameter. The Acanthamoeba organisms in the human corneas were identical in size and shape to Acanthamoeba organisms on an agar plate visualized with the same confocal microscope. Confocal microscopy is a useful method for identifying Acanthamoeba organisms in vivo within the corneal epithelium and anterior stroma.
https://www.semanticscholar.org/paper/Diagnosis-of-Acanthamoeba-keratitis-in-vivo-with-c-Winchester-Mathers/c024bcaa5ccf77e4b237b721f376da48df7631bc
The interaction of F-actin with phosphorylated and unphosphorylated myosins IA and IB from Acanthamoeba castellanii.<...
TY - JOUR. T1 - The interaction of F-actin with phosphorylated and unphosphorylated myosins IA and IB from Acanthamoeba castellanii.. AU - Albanesi, J. P.. AU - Hammer, J. A.. AU - Korn, E. D.. PY - 1983/8/25. Y1 - 1983/8/25. N2 - Myosins IA and IB from Acanthamoeba castellanii are single-headed molecules which, upon phosphorylation of their heavy chains by a specific kinase, express actin-activated Mg2+-ATPase activity. These myosins show no tendency to self-associate under assay conditions, a property which allows unambiguous kinetic and actin-binding data to be obtained. Both myosin isoenzymes exhibit a complex dependence of actomyosin ATPase activity on F-actin concentration. A conventional hyperbolic dependence is observed at low concentrations of F-actin but at higher F-actin concentrations, inhibition and then apparent reactivation are seen to occur. From those early portions of the velocity profiles which do not deviate from simple Michaelis-Menten type kinetics, values for the Vmax (10 ...
https://utsouthwestern.pure.elsevier.com/en/publications/the-interaction-of-f-actin-with-phosphorylated-and-unphosphorylat
What Is Acanthamoeba Keratitis, the Contact Lens Infection? | Health.comWhat Is Acanthamoeba Keratitis, the Contact Lens Infection? | Health.com
A rare eye infection called acanthamoeba keratitis is spreading in contact lens wearers. Find out more about acanthamoeba keratitis symptoms.
https://www.health.com/condition/eye-health/acanthamoeba-keratitis-contact-lens-infection
Can artificial tears prevent Acanthamoeba keratitis? An in vitro approach | Parasites & Vectors | Full TextCan artificial tears prevent Acanthamoeba keratitis? An in vitro approach | Parasites & Vectors | Full Text
In the present study, three artificial tear brands were selected according to the preservative agents (detergent or oxidative) or the lack of them to study their possible amoebicidal activity against trophozoites, as this is the initial state of the infection.. To study the viability of Acanthamoeba trophozoites after incubation with these tears, two different methods were used. The more traditional one, Trypan Blue stain, allows the differentiation of amoebae with the altered cell membrane and thus, identification of the non-viable ones. The second method used CTC stain to measure mitochondrial activity to determine the viability of the amoebae. This stain was developed for bacterial viability and then, adapted for Acanthamoeba in fluorometry by Kobayashi et al. [23]. In the present study, CTC stain for Acanthamoeba viability was used with flow cytometry for the first time.. One of the artificial tears tested using these two methods was Optava Fusion™. It contains Purite®, which is a soft ...
https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-018-2639-5
Kerala Government Optometrists Association | Acanthamoeba Keratitis Who, why, where and what to do? | Industry SpecialistKerala Government Optometrists Association | Acanthamoeba Keratitis Who, why, where and what to do? | Industry Specialist
Acanthamoeba Keratitis is a devastating eye infection which in developed countries most commonly occurs in contact lens wearers. Consultant Ophthalmologist Deepa Anijeet will summarise key concepts such as risk factors, diagnosis and treatment of Acanthamoeba Keratitis. It will also highlight key areas of research that offer hope for sufferers.
https://www.wcea.education/app/goak/elearning/optometrist/kerala-government-optometrists-association/176796/acanthamoeba-keratitis-who-why-where-and-what-to-do
The application of in vivo confocal scanning laser microscopy in the management of Acanthamoeba keratitis<...
TY - JOUR. T1 - The application of in vivo confocal scanning laser microscopy in the management of Acanthamoeba keratitis. AU - Matsumoto, Yukihiro. AU - Dogru, Murat. AU - Sato, Enrique Adan. AU - Katono, Yasuhiro. AU - Uchino, Yuichi. AU - Shimmura, Shigeto. AU - Tsubota, Kazuo. PY - 2007/7/25. Y1 - 2007/7/25. N2 - Purpose: To evaluate the role of in vivo laser scanning confocal microscopy (Heidelberg Retina Tomograph II, Rostock Cornea Module, HRTII-RCM) in the management of Acanthamoeba keratitis (AK). Methods: Four eyes of four patients with AK seen at Keio University Hospital at the Department of Ophthalmology were studied in this single-center, prospective, interventional case series. All patients were routinely examined by slit-lamp microscopy including corneal fluorescein staining. Best corrected visual acuity (BCVA) was also measured before and after the treatment for AK. Both the scraped corneal epithelium and soft contact lens (SCL) storage solution in each patients SCL case were ...
https://keio.pure.elsevier.com/en/publications/the-application-of-in-vivo-confocal-scanning-laser-microscopy-in--2
Acanthamoeba : Schaeffer Eye Center
Acanthamoeba are tiny amoeba like parasites found in water sources such as tap water, well water, hot tubs and soil or sewage systems. Eye infections can occur when contact is made with these parasites and is usually due to the improper care of contact lenses or unhygienic conditions.. Recent outbreaks of acanthamoeba infections have been noted by the Centers for Disease Control and Prevention throughout the U.S. The use of contact lens solutions that were contaminated during the manufacturing process led to an outbreak in 2007.. The good news is that with proper contact lens care, most cases can be avoided and that contact lens solutions undergo rigorous testing to ensure a sterile products reaches market.. ...
https://schaeffereyecenter.com/about-your-eyes/acanthamoeba/
Pathogenesis of Acanthamoeba Keratitis - Noorjahan PanjwaniPathogenesis of Acanthamoeba Keratitis - Noorjahan Panjwani
Acanthamoeba keratitis (AK) is a serious, debilitating, and intensely painful infection of the cornea caused by parasites of the genus Acanthamoeba. At present,...
http://grantome.com/grant/NIH/R01-EY009349-13
Genetic relatedness among isolates of Acanthamoeba based on RAPD analysis - Universiti Putra Malaysia Institutional RepositoryGenetic relatedness among isolates of Acanthamoeba based on RAPD analysis - Universiti Putra Malaysia Institutional Repository
Acanthamoeba is a pathogen frequently infecting brain, eyes, skin and lung of human and animal. Seven Acanthamoeba local isolates from various sources, two Acanthamoeba type strains and one strain of Hartmannella vermiformis were characterized for their genetic variability using randomly amplified polymorphic DNA (RAPD) technique using four different 10-mer oligonucleotides primers. Electrophoresis of the amplification products generated DNA bands ranging from approximately 0.25 to 7.50 kbp in size. A genetic relatedness among the isolates was examined using Dice similarity coefficient as the genetic distance measured between the strains of Acanthamoeba and H. vermiformis. Three distinct clusters could be separated at genetic distance of approximately 0.330. © 2006 Asian Network for Scientific Information. ...
http://psasir.upm.edu.my/18312/
Bowmans layer encystment in cases of persistent Acanthamoeba ke | OPTHBowmans layer encystment in cases of persistent Acanthamoeba ke | OPTH
Bowman’s layer encystment in cases of persistent Acanthamoeba keratitis Hideaki Yokogawa,1 Akira Kobayashi,1 Natsuko Yamazaki,1 Yasuhisa Ishibashi,2 Yosaburo Oikawa,3 Masaharu Tokoro,4 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, 2Department of Ophthalmology, East Washinomiya Hospital, Kuki, 3Department of Medical Zoology, Kanazawa Medical University, Kahoku, 4Department of Parasitology, Kanazawa University Graduate School of Medical Science, Kanazawa, JapanBackground: The purpose of this study was to report Acanthamoeba encystment in Bowman’s layer in Japanese cases of persistent Acanthamoeba keratitis (AK).Methods: Laser confocal microscopic images of the cornea were obtained in vivo from 18 consecutive eyes from 17 confirmed AK patients. Retrospectively, 14 cases treated over 4 months were categorized as a nonpersistent group and three cases that required prolonged therapy for more than 6 months were categorized as a
https://www.dovepress.com/bowmanrsquos-layer-encystment-in-cases-of-persistent-acanthamoeba-kera-peer-reviewed-article-OPTH
ASMscience | Is Acanthamoeba polyphag
Acanthamoeba polyphaga mimivirus (APMV) is the first member of a new family of nucleocytoplasmic large DNA viruses called the Mimiviridae. Another giant virus, named mamavirus, was discovered in 2008 and is considered another APMV strain. Moreover, nosocomially acquired pneumonias account for 10 to 15% of all hospital-acquired infections, and pneumonia is actually the leading cause of nosocomial infection in intensive care units (ICU), where ventilator-associated pneumonias (VAP) are the most frequently observed hospital-acquired infections and are associated with high morbidity and mortality. Mimivirus was one of the agents investigated by serological testing, among other conventional pneumonia agents. Among pneumonia patients with amoeba-associated pathogens, more had seroconversion to mimivirus (5 cases) than to any other pathogen. In addition, mimivirus was second among the four most frequently encountered agents of pneumonia diagnosed with high levels of evidence (3.8%), behind Pseudomonas
https://www.asmscience.org/content/book/10.1128/9781555816803.ch03
Acanthamoeba castellanii: a new high-throughput method for drug screening in vitro - Nottingham ePrintsAcanthamoeba castellanii: a new high-throughput method for drug screening in vitro - Nottingham ePrints
Despite significant public health impact, there is no specific antiprotozoal therapy for prevention and treatment of Acanthamoeba castellanii infection. There is a need for new and efficient anti-Acanthamoeba drugs that are less toxic and can reduce treatment duration and frequency of administration. In this context a new, rapid and sensitive assay is required for high-throughput activity testing and screening of new therapeutic compounds. A colorimetric assay based on sulforhodamine B (SRB) staining has been developed for anti-Acanthamoeba drug susceptibility testing and adapted to a 96-well microtiter plate format. Under these conditions chlorhexidine was tested to validate the assay using two clinical strains of A. castellanii (Neff strain, T4 genotype [IC50 4.68±0.6 _M] and T3 genotype [IC50 5.69±0.9 _M]). These results were in good agreement with those obtained by the conventional Alamar Blue assay, OCR cytotoxicity assay and manual cell counting method. Our new assay offers an ...
http://eprints.nottingham.ac.uk/44052/
Common staining techniques for highlighting Acanthamoeba cysts - Université dAngers
|p|A 36-year-old woman returning from holiday in Portugal presented with bilateral ocular pain and acute visual loss. Eye examination revealed an inflammation in the anterior segment associated with corneal keratitis. During her trip, she wore contact lenses and rinsed the storage case using tap water. Corneal scrapings, contact lenses and cleaning solution from the case were inoculated onto agar plates supplemented with heat-inactivated bacteria. Bilateral Acanthamoeba keratitis was diagnosed, as microscopic examination of cultures from the last two samples revealed typical, spherical double-walled cystic structures (Fig. 1).|/p|
https://hal.univ-angers.fr/hal-02872840
Increase in acid tolerance of Campylobacter jejuni through coincubation with amoebaeIncrease in acid tolerance of Campylobacter jejuni through coincubation with amoebae
Campylobacter jejuni is the leading bacterial cause of gastrointestinal diarrheal disease in humans worldwide. This zoonotic pathogen has a complex epidemiology due to its presence in many different host organisms. The overall aim of this thesis was to explore the role of amoebae of the genus Acanthamoeba as an intermediate host and vector for survival and dissemination of C. jejuni. Earlier studies have shown that C. jejuni can enter, survive and replicate within Acanthamoebae spp. In this thesis, I have shown that C. jejuni actively invades Acanthamoeba polyphaga. Once inside, C. jejuni could survive within the amoebae by avoiding localization to degradative lysosomes. We also found that A. polyphaga could protect C. jejuni in acid environments with pH levels far below the range in which the bacterium normally survives. Furthermore, low pH triggered C. jejuni motility and invasion of A. polyphaga. In an applied study I found that A. polyphaga also could increase the survival of C. jejuni in ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:372882
Acanthamoeba keratitisAcanthamoeba keratitis
Acanthamoeba keratitis may be limited to the epithelium in its early stages, resulting in epithelial dendrites and punctate epitheliopathy. Later stromal involvement classically results in a partial or complete paracentral ring infiltrate as seen in this photograph. The many amoeba visible on the confocal microscopy image confirmed the suspected etiology to this patients infiltrate.
http://webeye.ophth.uiowa.edu/eyeforum/atlas/pages/acanthamoeba/index.htm
Acanthamoeba keratitis in 194 patients: risk factors for bad outcomes and severe inflammatory complicationsAcanthamoeba keratitis in 194 patients: risk factors for bad outcomes and severe inflammatory complications
Background/aimsTo determine demographic and clinical features of patients with Acanthamoeba keratitis (AK) that are independent risk factors both for bad outcomes and for severe inflammatory complications (SIC).MethodsA retrospective audit of medical records of AK cases at Moorfields Eye Hospital fr
https://insights.ovid.com/british-ophthalmology/bjop/2018/10/000/acanthamoeba-keratitis-194-patients/23/00002388
A case of medication-resistant acanthamoeba keratitis treated by corneal crosslinking in Turkey.
Purpose. To report a case of medication-resistant acanthamoeba keratitis (AK) treated successfully by corneal crosslinking (CXL). Methods. A 26-year-old male with medication-resistant AK underwent a standard CXL procedure with local anesthesia, follo
http://www.biomedsearch.com/nih/case-medication-resistant-acanthamoeba-keratitis/24455365.html
Eye ParasitesEye Parasites
A. castellanii is a ubiquitous organism, found in many ecosystems worldwide. It is able to survive in harsh environmental circumstances - even in some contact lens solutions - and this is not the first occurrence of A. castellanii appearing in the eye. Acanthamoeba keratitis (AK) is a neglected malady frequently associated with contact lens wear.. Acanthamoeba infection of the cornea causes severe inflammation, intense pain and impaired vision, which is blinding if left untreated. Infection begins when the parasite is at its active feeding trophozoite stage and sticks to the corneal tissue before penetrating the lower stromal layer. The resulting opacity leads to less sharp vision and eventually blindness.. Acanthamoeba infections (not just in the eye) are being detected by clinicians with increasing frequency, especially as opportunistic infections in patients whose immune system is already compromised. This at-risk population is expanding as a result of increasing use of immune-suppressing ...
https://www.omicsonline.org/conferences-list/eye-parasites
Mimivirus, TEM - Stock Image C001/4438 - Science Photo LibraryMimivirus, TEM - Stock Image C001/4438 - Science Photo Library
Mimivirus. Transmission electron micrograph (TEM) of Acanthamoeba polyphaga mimivirus (APMV) particles. APMV is commonly known as the mimivirus. This virus consists of outer hairs, or fibrils (spikes), and a protein capsid (dark grey) enclosing a core (black) of DNA (deoxyribonucleic acid), the virus genetic material. APMVs classification as a pathogen is tentative, but it is now thought that it may cause viral pneumonia. Magnification: x9,300 when printed 10 centimetres wide. - Stock Image C001/4438
http://www.sciencephoto.com/media/78840/view
By releasing ADP, Acanthamoeba castellanii causes an increase in the cytosolic free calcium concentration and apoptosis in wish...
The role played by soluble molecules that may participate in acanthamoebal cytopathogenicity has yet to be fully characterized. We demonstrate here that Acanthamoeba castellanii trophozoites constitutively release ADP in the medium. Cell-free supernatants prepared from A. castellanii, by interaction with specific P2y2 purinoceptors expressed on the Wish cell membrane, caused a biphasic rise in [Ca2+]i, extensive cell membrane blebbing, cytoskeletal disorganization, and the breakdown of nuclei. Cell damage induced by amoebic supernatants was blocked by the P2y2 inhibitor Suramin. The same results were found in Wish cells exposed to purified ADP. These findings suggest that pathogenic free-living A. castellanii may have a cytopathic effect on human epithelial cells through ADP release, by a process that begins with a rise of cytosolic free-calcium concentration, and culminates in apoptosis. ...
http://eprints.uniss.it/7896/
Welcome to CDC stacks | Screening Pneumonia Patients for Mimivirus1 - 3183 | CDC Public Access | Emerging Infectious DiseasesWelcome to CDC stacks | Screening Pneumonia Patients for Mimivirus1 - 3183 | CDC Public Access | Emerging Infectious Diseases
Acanthamoeba polyphaga mimivirus (APM), a virus of free-living amebae, has reportedly caused human respiratory disease. Using 2 newly developed real-time PCR assays, we screened 496 respiratory specimens from 9 pneumonia-patient populations for APM. This virus was not detected in any specimen, which suggests it is not a common respiratory pathogen ...
https://stacks.cdc.gov/view/cdc/3183
Table 1 - Screening Pneumonia Patients for Mimivirus1 - Volume 14, Number 3-March 2008 - Emerging Infectious Disease journal -...
Acanthamoeba polyphaga mimivirus (APM), a virus of free-living amebae, has reportedly caused human respiratory disease. Using 2 newly developed real-time PCR assays, we screened 496 respiratory specimens from 9 pneumonia-patient populations for APM. This virus was not detected in any specimen, which suggests it is not a common respiratory pathogen.
https://wwwnc.cdc.gov/eid/article/14/3/07-1027-t1
Acanthamoeba containing endosymbiotic chlamydia isolated from hospital environments and its potential role in inflammatory...Acanthamoeba containing endosymbiotic chlamydia isolated from hospital environments and its potential role in inflammatory...
Environmental chlamydiae belonging to the Parachlamydiaceae are obligate intracellular bacteria that infect Acanthamoeba, a free-living amoeba, and are a risk for hospital-acquired pneumonia. However, whether amoebae harboring environmental chlamydiae actually survive in hospital environments is unknown. We therefore isolated living amoebae with symbiotic chlamydiae from hospital environments. One hundred smear samples were collected from Hokkaido University Hospital, Sapporo, Japan; 50 in winter (February to March, 2012) and 50 in summer (August, 2012), and used for the study. Acanthamoebae were isolated from the smear samples, and endosymbiotic chlamydial traits were assessed by infectivity, cytokine induction, and draft genomic analysis. From these, 23 amoebae were enriched on agar plates spread with heat-killed Escherichia coli. Amoeba prevalence was greater in the summer-collected samples (15/30, 50%) than those of the winter season (8/30, 26.7%), possibly indicating a seasonal variation (p = 0.096
https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-016-0906-1/figures/4
Effect of growth at low temperature on the uncoupling protein activity and expression in Acanthamoeba castellanii mitochondria ...
Tytuł projektu: Rozbudowa i przekształcenie bibliograficznej bazy danych AGRO w bazę bibliograficzno-abstraktową z wykorzystaniem oprogramowania YADDA. Nr umowy: POIG 02.03.02-00-031/09 (okres realizacji 2009-2013 ...
http://agro.icm.edu.pl/agro/element/bwmeta1.element.agro-00b1a320-e7fd-4c72-9882-0361848ce821?printView=true
DJO | Digital Journal of OphthalmologyDJO | Digital Journal of Ophthalmology
Innate immunity plays an important role in figting acanthamoeba infection (Hurt M, Alizadeh H et al. Infect Immun 2001 69(5):2988-2995). In an animal model of Acanthamoeba keratitis, exacerbation of keratitis occurred when neutrophil migration was inhibited, and resolution of keratitis occurred when neutrophils were recruited. Adaptive immunity may also play a role, as anti-Acanthamoeba IgA antibodies have been demonstrated in tears (Niederkorn JY et al. Cornea 2001 20(6):622-627 ...
http://www.djo.harvard.edu/print.php?url=/physicians/gr/296&print=1
CEA - Commissariat à lénergie atomique - In-depth study of Mollivirus sibericum , a new 30,000-y-old giant virus infecting...CEA - Commissariat à lénergie atomique - In-depth study of Mollivirus sibericum , a new 30,000-y-old giant virus infecting...
Acanthamoeba species are infected by the largest known DNA viruses. These include icosahedral Mimiviruses, amphora-shaped Pandoraviruses, and Pithovirus sibericum, the latter one isolated from 30,000-y-old permafrost. Mollivirus sibericum, a fourth type of giant virus, was isolated from the same permafrost sample. Its approximately spherical virion (0.6-µm diameter) encloses a 651-kb GC-rich genome encoding 523 proteins of which 64% are ORFans; 16% have their closest homolog in Pandoraviruses and 10% in Acanthamoeba castellanii probably through horizontal gene transfer. The Mollivirus nucleocytoplasmic replication cycle was analyzed using a combination of
https://hal-cea.archives-ouvertes.fr/cea-01825900?frbrVersion=6
Timeline: Contact solution maker failed to report | AMO Complete Moisture Plus Recall - SCHMIDT LLP see: The Schmidt Firm, PLLCTimeline: Contact solution maker failed to report | AMO Complete Moisture Plus Recall - SCHMIDT LLP see: The Schmidt Firm, PLLC
Key dates in the outbreak of eye infections linked to Advanced Medical Optics Complete MoisturePlus solution:. Feb. 2006- Nov. 2006: AMO receives nine reports involving patients infected with Acanthamoeba keratitis that go unreported.. March 2007: The CDC opens a multistate investigation into unusually high rates of the Acanthamoeba infection, which can result in permanent vision loss or blindness.. May 25, 2007: The CDC links AMOs Complete MoisturePlus to the outbreak and tells consumers to throw the product away.. May 26, 2007: AMO voluntarily recalls the solution under pressure from regulators at the CDC and the FDA.. May 29, 2007 to June 25, 2007: FDA inspectors arrive to investigate AMOs Irvine, Calif.-based headquarters. While there the FDA uncovers a series of problems, including the nine unreported complaint forms, which are finally submitted to the FDA.. Summer 2007: FDA officials schedule a meeting to discuss the problems uncovered at AMOs plant. No disciplinary action is ...
https://www.schmidtlaw.com/timeline-contact-solution-maker-failed-to-report/
An analysis of the incidence, management, clinical outcomes and risk factors of Acanthamoeba keratitis infections in a tertiary...An analysis of the incidence, management, clinical outcomes and risk factors of Acanthamoeba keratitis infections in a tertiary...
Author(s): Johnson ZK, Narayanan M, Siah WF, Anwar H, Figueiredo FC. Publication type: Conference Proceedings (inc. Abstract). Publication status: Published. Conference Name: ARVO 2015 Annual Meeting. Year of Conference: 2015. Online publication date: 01/06/2015. Acceptance date: 01/01/1900. ISSN: 1552-5783. Publisher: Association for Research in Vision and Ophthalmology. URL: http://iovs.arvojournals.org/article.aspx?articleid=2331626&resultClick=1. Series Title: Investigative Ophthalmology & Visual Science. ...
https://eprint.ncl.ac.uk/222426
Aperture: Works from the Castellani Art Museum Photography Collection | Castellani Art MuseumAperture: Works from the Castellani Art Museum Photography Collection | Castellani Art Museum
The aperture, in photography, is a thin light-blocking plate or interleaving set of adjustable plates that permits light to pass through a lens. The aperture, which is adjustable in size and allows the photographer to control the amount of light entering the camera is what, in part, permits the...
https://castellaniartmuseum.org/exhibitions/aperture-works-from-the-castellani-art-museum-photography-collection
Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling ...Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling ...
Ac encodes 15,455 compact intron-rich genes, a significant number of which are predicted to have arisen through inter-kingdom lateral gene transfer (LGT). A majority of the LGT candidates have undergone a substantial degree of intronization and Ac appears to have incorporated them into established transcriptional programs. Ac manifests a complex signaling and cell communication repertoire, including a complete tyrosine kinase signaling toolkit and a comparable diversity of predicted extracellular receptors to that found in the facultatively multicellular dictyostelids. An important environmental host of a diverse range of bacteria and viruses, Ac utilizes a diverse repertoire of predicted pattern recognition receptors, many with predicted orthologous functions in the innate immune systems of higher organisms.. ...
http://eprints.hud.ac.uk/id/eprint/28247/
Preventing Contact Contamination - KCBD NewsChannel 11 LubbockPreventing Contact Contamination - KCBD NewsChannel 11 Lubbock
If you wear contact lenses, how careful are you about keeping them clean? If a parasite climbs on to your contacts, you could end up with big problems -- Janet Donelly did. Shes blind in one eye now because of a serious eye infection. Acanthamoeba is a parasite that lives everywhere. Its in dirt and in plain old water from your tap to your swimming pool, and Janet knows now that a popular breeding ground for that tiny bug is your contact lens storage case.. I did use water to clean out the case itself like anybody when it gets dirty. You put it under the water and you wash it off just as you would a pot or a pan, says Donnelly, infection patient.. The infections are very difficult to get to go away. If we catch it after several weeks, or even several months, you could end up with permanent scarring and permanently decreased vision, says Dr. Christopher Rapuano, cornea specialist.. Dr. Rapuano says rinsing that case with soap and water may be to blame for Janets eye infection because soap ...
http://www.kcbd.com/story/2253962/preventing-contact-contamination
permafrostpermafrost
A new virus called Pithovirus sibericum has been isolated from 30,000 year old Siberian permafrost. It is the oldest DNA virus of eukaryotes ever isolated, showing that viruses can retain infectivity in nature for very long periods of time.. Pithovirus was isolated by inoculating cultures of the amoeba Acanthamoeba castellani with samples taken in the year 2000 from 30 meters below the surface of a late Pleistocene sediment in the Kolyma lowland region. This amoeba had been previously used to propagate other giant viruses, such as Mimivirus and Pandoravirus. Light microscopy of the cultures revealed the presence of ovoid particles which were subsequently shown by electron microscopy to resemble those of Pandoravirus. Pithovirus particles are flask-shaped and slightly larger than Pandoravirus - 1.5 microns long, 500 nm in diameter, encased by a 60 nm thick membrane. One end of the virus particle appears to be sealed with what the authors call a cork (photo). This feature, along with the shape of ...
http://www.virology.ws/tag/permafrost/
Richard NewsonRichard Newson
Thanks to all those who attended our Nelson conference. Links from the conference talks from Professor Fiona Stapleton are: Good AK (acanthamoeba keratitis) information websites: www.odak-project.eu/ www.cdc.gov/parasites/acanthamoeba/ Wearer and practitioner education www.moorfields.nhs.uk/content/healthy-habits-healthy-eyes www.cdc.gov/contactlenses/contact-lens-health-week.html Keynote Speakers: Marc Bloomenstein OD, FAAODr. Marc R. Bloomenstein is a 1990 graduate of the University of California at Los Angeles[…]. ...
http://www.contactlens.org.nz/author/richard/
EventsEvents
Thanks to all those who attended our Nelson conference. Links from the conference talks from Professor Fiona Stapleton are: Good AK (acanthamoeba keratitis) information websites: www.odak-project.eu/ www.cdc.gov/parasites/acanthamoeba/ Wearer and practitioner education www.moorfields.nhs.uk/content/healthy-habits-healthy-eyes www.cdc.gov/contactlenses/contact-lens-health-week.html Keynote Speakers: Marc Bloomenstein OD, FAAODr. Marc R. Bloomenstein is a 1990 graduate of the University of California at Los Angeles[…]. ...
http://www.contactlens.org.nz/category/events/
My Traitors Heart - Jonathan PollardMy Traitors Heart - Jonathan Pollard
Posted on 08/07/2002 1:21:10 PM PDT by robowombat. My Traitors Heart - Jonathan Pollard By Anthony C. LoBaido Published 06. 21. 02 at 21:34 Sierra Time The Politically Incorrect Spy: Time to send him home to Israel. Jonathan Pollard was a very naughty boy - not only did he spy for Israel, one of Americas staunchest allies -- he dared to stand on the side of almost every politically incorrect issue of the mid 1980s. Now as Pollard languishes in a North Carolina prison in failing health, it would behoove American patriots to reexamine the case -- free of the media spin provided by Wolf Blitzer, Seymour Hersh and CBS news. We must ask ourselves -- and President Bush Jr. -- if it is not indeed time for Mr. Pollard to go home to Israel. When I first analyzed the case of Jonathan Pollard I had no idea how closely Pollards life and interests mirrored my own. In fact, I became obsessed with every detail of his case -- reading, studying and writing about Pollard for up to 18 hours per day. Before long ...
http://www.freerepublic.com/focus/f-news/729339/posts?page=30
Pheromone trapsPheromone traps
Piergiorgio Castellani is the fourth generation of the Castellani family to run the estates. Castellani have six properties, five in Chianti (in Colline Pisane) and one in Chianti Classico. Its a sizeable portfolio for a family-owned winery: • 300ha vineyards. Sourcing from growers in a further 1,000ha. • 90 employees • 26 million bottles per […]. ...
https://www.premierwinetraining.com/tag/pheromone-traps/
I Started Out As A Child: Acanthamoeba and Other Things I Knew Nothing AboutI Started Out As A Child: Acanthamoeba and Other Things I Knew Nothing About
OK, back to me. When I went to my cornea specialist, the end of July, he was pleased with my progress in healing from the herpes simplex. My eye looked normal and the cornea was healing. At the beginning of August, my eye became very inflamed, and my vision was limited. I went back to the eye doctor and he assumed the herpes virus took a turn for the worse. He increased the dosage of steroid drops and had me return in a few days. I learned something else in this process. Amoeba on steroids are much more aggressive and become stronger. It took almost 3 weeks to diagnose my problem. By then, my cornea was extremely cloudy and my vision was gone. I could see light and shadow, but no images. My eye was sensitive to light, and there was a lot of pain. My head ached constantly. I was sent to the Moran Eye Center in Salt Lake City where I was diagnosed by using a confocal microscope and scraping the cornea for a culture. I left the eye center with 3 different kinds of pills and 8 different drops, NOT ...
http://aclangston.blogspot.com/2014/03/acanthamoeba-and-other-things-i-knew.html?showComment=1395846233087
I Started Out As A Child: Acanthamoeba and Other Things I Knew Nothing AboutI Started Out As A Child: Acanthamoeba and Other Things I Knew Nothing About
OK, back to me. When I went to my cornea specialist, the end of July, he was pleased with my progress in healing from the herpes simplex. My eye looked normal and the cornea was healing. At the beginning of August, my eye became very inflamed, and my vision was limited. I went back to the eye doctor and he assumed the herpes virus took a turn for the worse. He increased the dosage of steroid drops and had me return in a few days. I learned something else in this process. Amoeba on steroids are much more aggressive and become stronger. It took almost 3 weeks to diagnose my problem. By then, my cornea was extremely cloudy and my vision was gone. I could see light and shadow, but no images. My eye was sensitive to light, and there was a lot of pain. My head ached constantly. I was sent to the Moran Eye Center in Salt Lake City where I was diagnosed by using a confocal microscope and scraping the cornea for a culture. I left the eye center with 3 different kinds of pills and 8 different drops, NOT ...
http://aclangston.blogspot.com/2014/03/acanthamoeba-and-other-things-i-knew.html?showComment=1396054380079
Metronidazole | Colorado PROFILES
Brondfield MN, Reid MJ, Rutishauser RL, Cope JR, Tang J, Ritter JM, Matanock A, Ali I, Doernberg SB, Hilts-Horeczko A, DeMarco T, Klein L, Babik JM. Disseminated Acanthamoeba infection in a heart transplant recipient treated successfully with a miltefosine-containing regimen: Case report and review of the literature. Transpl Infect Dis. 2017 Apr; 19(2 ...
https://profiles.ucdenver.edu/display/211567
Faculty journal articles | School of Medicine | Zucker School of Medicine at Hofstra/NorthwellFaculty journal articles | School of Medicine | Zucker School of Medicine at Hofstra/Northwell
Clinical Characteristics of Acanthamoeba Keratitis Infections in 28 States, 2008 to 2011, J. Ross, S. L. Roy, W. D. Mathers, D. C. Ritterband, J. S. Yoder, T. Ayers, R. D. Shah, M. E. Samper, C. Y. Shih, A. Schmitz, and A. C. Brown. ...
https://academicworks.medicine.hofstra.edu/som-ophthalmology-facultypubs/
AmoebaAmoeba
Acanthamoeba can cause amoebic keratitis and encephalitis in humans. Balamuthia mandrillaris is the cause of (often fatal) ... "Acanthamoeba , Microworld". www.arcella.nl. Archived from the original on 18 August 2016. Retrieved 21 August 2016. "Microscopy ... This finding suggests that the ''Acanthamoeba'' are capable of some form of meiosis and may be able to undergo sexual ... Orthologs of genes employed in meiosis of sexual eukaryotes have recently been identified in the Acanthamoeba genome. These ...
https://en.wikipedia.org/wiki/Amoeba
DiscoseaDiscosea
Acanthamoeba sp. Thecamoeba sp. Mayorella (Amoebozoa, Discosea) Class Discosea Cavalier-Smith 2004 stat. nov. Adl et al. 2018 ...
https://en.wikipedia.org/wiki/Discosea
AcanthamoebidaeAcanthamoebidae
Acanthamoeba can also be the source of infections in the lungs, sinuses, skin, and eyes. "www.ncbi.nlm.nih.gov". Retrieved 2009 ... Acanthamoeba spp. can be potentially pathogenic to humans and animals. Typically, a person or animal with a normally ... Its most prominent member, Acanthamoeba, can be potentially pathogenic to humans and animals. It has been described as having a ... It gets its name from Acanthamoeba, its best-known member. However, it also includes other species, such as Comandonia ...
https://en.wikipedia.org/wiki/Acanthamoebidae
Free-living Amoebozoa infectionFree-living Amoebozoa infection
Acanthamoeba spp. and Balamuthia mandrillaris cysts and trophozoites are found in tissue.[citation needed] In Acanthamoeba ... Unlike N. fowleri, Acanthamoeba and Balamuthia have only two stages, cysts and trophozoites, in their life cycle. No ... In addition, Acanthamoeba spp. can cause granulomatous skin lesions and, more seriously, keratitis and corneal ulcers following ... Acanthamoeba spp. causes mostly subacute or chronic granulomatous amoebic encephalitis (GAE), with a clinical picture of ...
https://en.wikipedia.org/wiki/Free-living_Amoebozoa_infection
Symbiosis in AmoebozoaSymbiosis in Amoebozoa
Parachlamydia acanthamoebae) to counter giant viruses from Marseilleviridae and Mimiviridae. Acanthamoeba that are infected ... Acanthamoeba that are not infected by the symbiont or virus have the highest fitness with a doubling time that is twice as fast ... D. discoideum and other social amoeba differ from free living Acanthamoeba in that instead of encysting, they undergo a social ... Acanthamoeba hattchettii is one species affected by giant viruses, and some use a bacterial symbiont ( ...
https://en.wikipedia.org/wiki/Symbiosis_in_Amoebozoa
MyosinMyosin
Pollard TD, Korn ED (July 1973). "Acanthamoeba myosin. I. Isolation from Acanthamoeba castellanii of an enzyme similar to ... Following the discovery in 1973 of enzymes with myosin-like function in Acanthamoeba castellanii, a global range of divergent ...
https://en.wikipedia.org/wiki/Myosin
Richard VobesRichard Vobes
Acanthamoeba keratitis "Home". BaldExplorer.com. Vobes.com The Naked Englishman - Richard Vobes' daily audio journal VOBES show ... In 2006 Vobes discovered he had been infected with Acanthamoeba Keratitis, a blinding condition in his left eye caught from ...
https://en.wikipedia.org/wiki/Richard_Vobes
Sappinia diploideaSappinia diploidea
"Acanthamoeba: Overview - eMedicine". Retrieved 2009-01-11. Gelman BB, Rauf SJ, Nader R, et al. (May 2001). "Amoebic ... Visvesvara GS; Moura H; Schuster FL (June 2007). "Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., ...
https://en.wikipedia.org/wiki/Sappinia_diploidea
ProcabacteriaceaeProcabacteriaceae
Heinz, E; Kolarov, I; Kästner, C; Toenshoff, ER; Wagner, M; Horn, M (June 2007). "An Acanthamoeba sp. containing two ... The sole genus, "Procabacter", was identified as an obligate endosymbiont of Acanthamoeba. Horn, M; Fritsche, TR; Linner, T; ... related to the beta-Proteobacteria: proposal of 'Candidatus Procabacter acanthamoebae' gen. nov., sp. nov". International ... Gautom, RK; Harzenetter, MD; Wagner, M (March 2002). "Obligate bacterial endosymbionts of Acanthamoeba spp. ...
https://en.wikipedia.org/wiki/Procabacteriaceae
ApicomplexaApicomplexa
Acanthamoeba, Naegleria). If they had cell walls, they also could be included in plant kingdom between bacteria or yeasts. ...
https://en.wikipedia.org/wiki/Apicomplexa
LobosaLobosa
test (Tubulinea) Acanthamoeba sp. (Discosea) Thecamoeba sp. (Discosea) Cavalier-Smith, Thomas; Chao, Ema E.; Lewis, Rhodri ( ...
https://en.wikipedia.org/wiki/Lobosa
ParachlamydiaParachlamydia
Species include P. acanthamoeba. List of bacterial orders List of bacteria genera G. Greub (5 January 2009). "Parachlamydia ... acanthamoebae, an emerging agent of pneumonia". Clinical Microbiology and Infection. 15 (1): 18-28. doi:10.1111/j.1469- ...
https://en.wikipedia.org/wiki/Parachlamydia
AmoebozoaAmoebozoa
Entamoeba histolytica Acanthamoeba Balamuthia mandrillaris Endolimax The recently available Acanthamoeba genome sequence ... This finding suggests that Acanthamoeba is capable of some form of meiosis and may be able to undergo sexual reproduction. In ... test (Lobosa: Tubulinea) Acanthamoeba sp. (Lobosa: Discosea) Thecamoeba sp. (Lobosa: Discosea) Entamoeba histolytica ... Acanthamoeba, Arcella, Difflugia etc.). The latter is made up of both amoeboid and flagellated cells, characteristically with ...
https://en.wikipedia.org/wiki/Amoebozoa
AcetylcholineAcetylcholine
The protist pathogen Acanthamoeba spp. has shown evidence of the presence of ACh, which provides growth and proliferative ... Baig AM, Ahmad HR (June 2017). "Evidence of a M1-muscarinic GPCR homolog in unicellular eukaryotes: featuring Acanthamoeba spp ... Discovery of Acetylcholine and the Components of the Human Cholinergic System in a Primitive Unicellular Eukaryote Acanthamoeba ...
https://en.wikipedia.org/wiki/Acetylcholine
MimivirusMimivirus
"Acanthamoeba polyphaga mimivirus, complete genome". NCBI. Claverie, Jean-Michel; et al. (2006). "Mimivirus and the emerging ... This genus contains a single identified species named Acanthamoeba polyphaga mimivirus (APMV). It also refers to a group of ... APMV was discovered accidentally in 1992 within the amoeba Acanthamoeba polyphaga, after which it is named, during research ...
https://en.wikipedia.org/wiki/Mimivirus
Balamuthia infectionBalamuthia infection
Acanthamoeba infection James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical ...
https://en.wikipedia.org/wiki/Balamuthia_infection
ChlorhexidineChlorhexidine
... eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis. Chlorhexidine is very ... Alkharashi M, Lindsley K, Law HA, Sikder S (2015). "Medical interventions for acanthamoeba keratitis". Cochrane Database Syst ...
https://en.wikipedia.org/wiki/Chlorhexidine
PolyhexanidePolyhexanide
PHMB eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis. It is sold as a swimming pool and spa ... "Medical interventions for acanthamoeba keratitis". Cochrane Database Syst Rev. 2 (2): CD0010792. doi:10.1002/14651858.CD010792. ...
https://en.wikipedia.org/wiki/Polyhexanide
ParachlamydiaceaeParachlamydiaceae
TUME1 endosymbiont of Acanthamoeba sp. UWC22 endosymbiont of Acanthamoeba sp. UWE1 Uncultured lineages include: Neochlamydia ... Trophozoites of Acanthamoeba hosting these strains were isolated from asymptomatic women in Germany and also in an outbreak of ... 2010 Isolated Endosymbionts include: Hall's coccus P9 UV-7 endosymbiont of Acanthamoeba sp. ... turtle type 1 environmental Neochlamydia corvenA4 cvC15 cvC7 cvE5 Parachlamydia acanthamoebae has variable Gram staining ...
https://en.wikipedia.org/wiki/Parachlamydiaceae
List of commonly used taxonomic affixesList of commonly used taxonomic affixes
Acanthamoeba ("spiny amoeba") aeto-: Pronunciation: /aɛto/. Origin: Ancient Greek: ἀετός (aetós). Meaning: eagle. Examples: ...
https://en.wikipedia.org/wiki/List_of_commonly_used_taxonomic_affixes
KeratitisKeratitis
It is usually caused by Acanthamoeba. On May 25, 2007, the U.S. Center for Disease Control issued a health advisory due to ... Lorenzo-Morales, Jacob; Khan, Naveed A.; Walochnik, Julia (2015). "An update on Acanthamoeba keratitis: diagnosis, pathogenesis ... "The potential pathogenicity of chlorhexidine-sensitive Acanthamoeba strains isolated from contact lens cases from asymptomatic ... increased risk of Acanthamoeba keratitis associated with use of Advanced Medical Optics Complete Moisture Plus Multi-Purpose ...
https://en.wikipedia.org/wiki/Keratitis
BetaproteobacteriaBetaproteobacteria
The name "Procabacteriales" was also proposed for an order of endosymbionts of Acanthamoeba, but since they cannot be grown in ... Horn M, Fritsche TR, Linner T, Gautom RK, Harzenetter MD, Wagner M (2002). "Obligate bacterial endosymbionts of Acanthamoeba ... related to the beta-Proteobacteria: proposal of " Candidatus Procabacter acanthamoebae" gen. nov., sp. nov". International ...
https://en.wikipedia.org/wiki/Betaproteobacteria
Cancer dormancyCancer dormancy
This eukaryotic encystation in Acanthamoeba spp., is known to involve a crosstalk between the trophozoite form of the cell and ... Recently, scientists from Aga Khan University Pakistan, have extended the studies of encystation in Acanthamoeba to induce ... Recently, model pathogenic eukaryotic cell encystation has been linked to cancer cell dormancy, Acanthamoeba spp. were studied ...
https://en.wikipedia.org/wiki/Cancer_dormancy
MarseilleviridaeMarseilleviridae
A second member is Acanthamoeba castellanii lausannevirus. Two additional viruses have been isolated but have yet to be named. ... The first member of this family recognized has been named Acanthamoeba polyphaga marseillevirus. ...
https://en.wikipedia.org/wiki/Marseilleviridae
AuranofinAuranofin
... may be useful in the prevention and control of Acanthamoeba infections, and in the treatment of primary amoebic ... Loufouma Mbouaka A, Leitsch D, Koehsler M, Walochnik J (August 2021). "Antimicrobial effect of auranofin against Acanthamoeba ... meningoencephalitis, caused by pathogenic free-living amoebae Acanthamoeba spp. and Naegleria fowleri, respectively. In a cell- ...
https://en.wikipedia.org/wiki/Auranofin
UTP-monosaccharide-1-phosphate uridylyltransferaseUTP-monosaccharide-1-phosphate uridylyltransferase
Rudick VL, Weisman RA (1974). "Uridine diphosphate glucose pyrophosphorylase of Acanthamoeba castellanii. Purification, kinetic ...
https://en.wikipedia.org/wiki/UTP-monosaccharide-1-phosphate_uridylyltransferase
Tryptophan synthaseTryptophan synthase
Anderson I, Watkins R, Samuelson J, Spencer D, Majoros W, Grey M, Loftus B (August 2005). "Gene Discovery in the Acanthamoeba ...
https://en.wikipedia.org/wiki/Tryptophan_synthase
AntiparasiticAntiparasitic
Kusrini E, Hashim F, Azmi WN, Amin NM, Estuningtyas A (2016). "A novel antiamoebic agent against Acanthamoeba sp. - A causative ...
https://en.wikipedia.org/wiki/Antiparasitic
PerimycinPerimycin
Acanthamoeba and Infectious Crystalline Keratopathy". American Journal of Ophthalmology. 148 (1): 13-19.e2. doi:10.1016/j.ajo. ...
https://en.wikipedia.org/wiki/Perimycin
PandoravirusPandoravirus
Unlike in other cases with such giant viruses, the large particles within Acanthamoeba were not mistaken for bacteria. The ... Scheid P, Hauröder B, Michel R (2010). "Investigations of an extraordinary endocytobiont in Acanthamoeba sp.: development and ...
https://en.wikipedia.org/wiki/Pandoravirus
Acanthamoeba Keratitis FAQs | Acanthamoeba | Parasites | CDCAcanthamoeba Keratitis FAQs | Acanthamoeba | Parasites | CDC
What is Acanthamoeba keratitis? Acanthamoeba keratitis is a rare but serious infection of the eye that can result in permanent ... This infection is caused by a microscopic, free-living ameba (single-celled living organism) called Acanthamoeba. Acanthamoeba ... Acanthamoeba amebas are very common in nature and can be found in bodies of water (for example, lakes and oceans), soil, and ... Acanthamoeba keratitis is most common in people who wear contact lenses, but anyone can develop the infection. For people who ...
https://www.cdc.gov/parasites/acanthamoeba/gen_info/acanthamoeba_keratitis.html
Acanthamoeba | Blogs | CDCAcanthamoeba | Blogs | CDC
Acanthamoeba - Sharing our stories on preparing for and responding to public health events ... Tags Acanthamoeba, contact lens, contact lens health week, contacts, eye infections, eyes, handwashing, microbial keratitis ...
https://blogs.cdc.gov/publichealthmatters/tag/acanthamoeba/
Etymologia: Acanthamoeba - Volume 26, Number 8-August 2020 - Emerging Infectious Diseases journal - CDC
... classified as the genus Acanthamoeba by Volkonsky. It was later found to be the etiologic agent of Acanthamoeba granulomatous ... Ecology of Acanthamoeba. Rev Infect Dis. 1991;13(Suppl 5):S385-7. DOIPubMedGoogle Scholar ... Acanthamoeba: biology and increasing importance in human health. FEMS Microbiol Rev. 2003;16:273-307.PubMedGoogle Scholar ... Acanthamoeba [ǝˌ́́́́kæn.Өǝʹmi.bǝ]. From the Greek akantha (spike/thorn), which was added before amoeba (change) to describe ...
https://wwwnc.cdc.gov/eid/article/26/8/et-2608_article
Acanthamoeba - Encyclopedia of LifeAcanthamoeba - Encyclopedia of Life
Known occurrences, collected specimens and observations of Acanthamoeba. View this species on GBIF ...
https://www.eol.org/pages/62538
Acanthamoeba Keratitis: Symptoms, Treatment & PreventionAcanthamoeba Keratitis: Symptoms, Treatment & Prevention
Acanthamoeba keratitis is a rare, serious eye infection caused by a tiny organism. It can lead to vision loss or total ... How common is acanthamoeba keratitis?. Acanthamoeba keratitis is rare. In the US, only one to two people per million contact ... What causes acanthamoeba keratitis?. The acanthamoeba causes this eye infection. The amoeba attaches to the cells on the outer ... What is acanthamoeba keratitis?. Acanthamoeba keratitis is a serious infection that affects the cornea (clear outer covering of ...
https://my.clevelandclinic.org/health/diseases/21560-acanthamoeba-keratitis
Acanthamoeba Keratitis Treatment & Symptoms | CooperVisionAcanthamoeba Keratitis Treatment & Symptoms | CooperVision
Information about acanthamoeba keratitis, its treatment and symptoms can be found at CooperVision. Reduce your chances of being ... What are the symptoms of Acanthamoeba keratitis?. Symptoms of Acanthamoeba keratitis include the following:. *Sensitivity to ... What can I do to help reduce the chances of contracting Acanthamoeba keratitis?. A trauma to the cornea (the clear dome that ... Infection of Acanthamoeba keratitis could happen through cuts or other eye traumas; exposure to contaminated water; or poor ...
https://coopervision.com/eye-health-and-vision/acanthamoeba-keratitis
RCSB PDB - 2B8P: Crystal structure of Acanthamoeba polyphaga mimivirus NDK, the first viral nucleoside diphosphate kinaseRCSB PDB - 2B8P: Crystal structure of Acanthamoeba polyphaga mimivirus NDK, the first viral nucleoside diphosphate kinase
Crystal structure of Acanthamoeba polyphaga mimivirus NDK, the first viral nucleoside diphosphate kinase ... Crystal structure of Acanthamoeba polyphaga mimivirus NDK, the first viral nucleoside diphosphate kinase. *PDB DOI: 10.2210/ ... The analysis of the Acanthamoeba polyphaga mimivirus genome revealed the first virus-encoded nucleoside diphosphate kinase (NDK ... The analysis of the Acanthamoeba polyphaga mimivirus genome revealed the first virus-encoded nucleoside diphosphate kinase (NDK ...
https://www.rcsb.org/structure/2b8p
Acanthamoeba and disinfecting contact lens solutions | British Journal of OphthalmologyAcanthamoeba and disinfecting contact lens solutions | British Journal of Ophthalmology
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
https://bjo.bmj.com/content/86/12/1461.2.info
SEQUENCES OF BALAMUTHIA IN THE DNA DATABASES | Acanthamoeba and free-living amoebaeSEQUENCES OF BALAMUTHIA IN THE DNA DATABASES | Acanthamoeba and free-living amoebae
Acanthamoeba at The Ohio State University. *Acanthamoeba sequence types *Phylogenetic relationships among Acanthamoeba sequence ... Genomes of Acanthamoeba. *Acanthamoeba DNA databases *Nuclear ribosomal small subunit (18S) gene sequences *"Almost complete" ... Molecular analysis of Acanthamoeba and free-living amoebae *RECENT NEWS ABOUT FREE-LIVING AMOEBAE ... Chris Wakley on Acanthamoeba at The Ohio State University. *Paul Fuerst on Phylogenetic relationships among subgroups within T4 ...
https://u.osu.edu/acanthamoeba/sequences-of-balamuthia-in-the-dna-databases/
Reusable Contact Lens Use Raises Acanthamoeba Keratitis Risk - Infectious Disease AdvisorReusable Contact Lens Use Raises Acanthamoeba Keratitis Risk - Infectious Disease Advisor
Acanthamoeba keratitis risk factors for daily wear contact lens users: a case control study.Ophthalmol. Published online August ... Patients who wear reusable contact lenses have more than 3 times the risk of developing Acanthamoeba keratitis than those who ... Reusable contact lens use is linked to significantly higher odds of Acanthamoeba keratitis (AK) compared with daily disposable ... Close more info about Reusable Contact Lens Use Raises Acanthamoeba Keratitis Risk ...
https://www.infectiousdiseaseadvisor.com/home/general-infectious-disease/daily-disposable-contact-lenses-reduce-risk-of-infection/
The role of Src kinase in the biology and pathogenesis of Acanthamoeba castellanii | Parasites & Vectors | Full TextThe role of Src kinase in the biology and pathogenesis of Acanthamoeba castellanii | Parasites & Vectors | Full Text
Here, we evaluated the role of Src, a non-receptor protein tyrosine kinase in the biology and pathogenesis of Acanthamoeba. ... Conversely, invasion of Acanthamoeba by pathogenic bacteria was stimulated by Src kinase inhibition. ... Acanthamoeba species are the causative agents of fatal granulomatous encephalitis in humans. Haematogenous spread is thought to ... From: The role of Src kinase in the biology and pathogenesis of Acanthamoeba castellanii ...
https://parasitesandvectors.biomedcentral.com/articles/10.1186/1756-3305-5-112/figures/2
In Vitro Evaluation of the Inhibitory Effect of Topical Ophthalmic Agents on Acanthamoeba Viability | TVST | ARVO JournalsIn Vitro Evaluation of the Inhibitory Effect of Topical Ophthalmic Agents on Acanthamoeba Viability | TVST | ARVO Journals
Neuraminidase activity in acanthamoeba species trophozoites and cysts.. In Vitro Interactions of Fusarium and Acanthamoeba with ... and biocides against the trophozoite and cyst stages of Acanthamoeba polyphaga (ATCC 30461) and Acanthamoeba castellanii (ATCC ... Acanthamoeba is a genus of small, free-living amoebae common to most soil and freshwater habitats.1 The organism has a life ... National outbreak of Acanthamoeba keratitis associated with use of a contact lens solution, United States. Emerg Infect Dis. ...
https://tvst.arvojournals.org/article.aspx?articleid=2752036&resultClick=1
Acanthamoeba containing endosymbiotic chlamydia isolated from hospital environments and its potential role in inflammatory...Acanthamoeba containing endosymbiotic chlamydia isolated from hospital environments and its potential role in inflammatory...
Acanthamoebae were isolated from the smear samples, and endosymbiotic chlamydial traits were assessed by infectivity, cytokine ... These findings are the first demonstration of the distribution in a hospital of a living Acanthamoeba carrying an endosymbiotic ... Three amoebae contained environmental chlamydiae; however, only one amoeba (Acanthamoeba T4) with an environmental chlamydia ( ... to be Acanthamoeba, and cultures in PYG medium were established for 11 of these amoebae. ...
https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-016-0906-1/metrics
Acanthamoeba polyphaga mimivirus Virophage Seroconversion in Travelers Returning from LaosAcanthamoeba polyphaga mimivirus Virophage Seroconversion in Travelers Returning from Laos
Title : Acanthamoeba polyphaga mimivirus Virophage Seroconversion in Travelers Returning from Laos Personal Author(s) : Parola ... Increased antibodies against an Acanthamoeba polyphaga mimivirus virophage indicated seroconversion. While in Laos, they had ...
https://stacks.cdc.gov/view/cdc/18734
Acanthamoeba Keratitis| CDCAcanthamoeba Keratitis| CDC
Access Acanthamoeba Keratitis case definitions; uniform criteria used to define a disease for public health surveillance. ...
https://ndc.services.cdc.gov/?p=126597
Etymologia: Acanthamoeba - Volume 26, Number 8-August 2020 - Emerging Infectious Diseases journal - CDC
... classified as the genus Acanthamoeba by Volkonsky. It was later found to be the etiologic agent of Acanthamoeba granulomatous ... Ecology of Acanthamoeba. Rev Infect Dis. 1991;13(Suppl 5):S385-7. DOIPubMedGoogle Scholar ... Acanthamoeba: biology and increasing importance in human health. FEMS Microbiol Rev. 2003;16:273-307.PubMedGoogle Scholar ... Acanthamoeba [ǝˌ́́́́kæn.Өǝʹmi.bǝ]. From the Greek akantha (spike/thorn), which was added before amoeba (change) to describe ...
https://wwwnc-origin.cdc.gov/eid/article/26/8/et-2608_article
CYTOCHEMICAL IDENTIFICATION OF PHOSPHATASE ACTIVITY IN THE CONTRACTILE VACUOLE OF ACANTHAMOEBA CASTELLANII | Journal of Cell...CYTOCHEMICAL IDENTIFICATION OF PHOSPHATASE ACTIVITY IN THE CONTRACTILE VACUOLE OF ACANTHAMOEBA CASTELLANII | Journal of Cell...
CYTOCHEMICAL IDENTIFICATION OF PHOSPHATASE ACTIVITY IN THE CONTRACTILE VACUOLE OF ACANTHAMOEBA CASTELLANII , Journal of Cell ... THE FINE STRUCTURE OF ACANTHAMOEBA CASTELLANII (NEFF STRAIN) : II. Encystment THE FINE STRUCTURE OF ACANTHAMOEBA CASTELLANII : ... CYTOCHEMICAL IDENTIFICATION OF PHOSPHATASE ACTIVITY IN THE CONTRACTILE VACUOLE OF ACANTHAMOEBA CASTELLANII Blair Bowers, Blair ... Blair Bowers, Edward D. Korn; CYTOCHEMICAL IDENTIFICATION OF PHOSPHATASE ACTIVITY IN THE CONTRACTILE VACUOLE OF ACANTHAMOEBA ...
https://rupress.org/jcb/article/59/3/784/1887/CYTOCHEMICAL-IDENTIFICATION-OF-PHOSPHATASE
Contact lens care solution killing efficacy against Acanthamoeba castellanii by in vitro testing and live-imaging -...Contact lens care solution killing efficacy against Acanthamoeba castellanii by in vitro testing and live-imaging -...
In the past decade there has been an increased incidence of Acanthamoeba keratitis, particularly in contact lens wearers. The ... Contact lens care solution killing efficacy against Acanthamoeba castellanii by in vitro testing and live-imaging ... These observations are in keeping with care solution biocides having prominent activity at the plasma membrane of Acanthamoeba. ... Contact lens care solution killing efficacy against Acanthamoeba castellanii by in vitro testing and live-imaging. Contact Lens ...
https://nrl.northumbria.ac.uk/id/eprint/30790/
IMSEAR at SEARO: Acanthamoeba encephalitis.
We present a fatal case of Acanthamoeba encephalitis in a 63-year-old female from India where acanthamoebae were demonstrated ... Acanthamoeba encephalitis. Indian Journal of Medical Microbiology. 2008 Apr-Jun; 26(2): 182-4. ...
https://imsear.searo.who.int/handle/123456789/54137
Acanthamoeba infection in an interhemispheric ependymal cyst: a case report. - Nuffield Department of Surgical Sciences
CONCLUSION: Acanthamoeba may cause secondary infection in an underlying brain cyst. A suspicion of such an infection must be ... However, Acanthamoeba infection in an intracranial ependymal cyst has not been reported in the literature. CASE DESCRIPTION: A ... The cyst fluid turned out be infected with Acanthamoeba. The patient was treated successfully with decompression of the cyst ... CONCLUSION: Acanthamoeba may cause secondary infection in an underlying brain cyst. A suspicion of such an infection must be ...
https://www.nds.ox.ac.uk/publications/311487?b12da624-a6d4-11ed-a597-061ab7f93640
DHS Search Results | Wisconsin Department of Health ServicesDHS Search Results | Wisconsin Department of Health Services
Acanthamoeba Keratitis. … or months, may include: Eye pain Eye redness Blurred vision Sensitivity to light Sensation of ...
https://dhs.wisconsin.gov/search?search=something&f%5B0%5D=field_topics%3A987&f%5B1%5D=field_topics%3A1884&f%5B2%5D=field_topics%3A1073&f%5B3%5D=field_topics%3A1904
Evidence for differential intracellular localization of the Acanthamoeba myosin isoenzymes - WikidataEvidence for differential intracellular localization of the Acanthamoeba myosin isoenzymes - Wikidata
Evidence for differential intracellular localization of the Acanthamoeba myosin isoenzymes. scientific article published on 01 ...
https://m.wikidata.org/wiki/Q72145771
Attacking Acanthamoeba KeratitisAttacking Acanthamoeba Keratitis
Acanthamoeba keratitis (AK) is a rare but very serious infection that can lead to vision loss or blindness.1 It is caused by a ... Attacking Acanthamoeba Keratitis. How to spot and treat this rare but serious condition and reduce risk of vision loss.. By ... The patient was cultured for Acanthamoeba, had an HSV PCR and her contact lens was cultured for fungi, bacteria and ... 2. IVCM showed Acanthamoeba cysts at the patients follow-up exam. Click image to enlarge.. ...
https://www.reviewofcontactlenses.com/article/attacking-acanthamoeba-keratitis
Diagnosis of Acanthamoeba keratitis in vivo with confocal microscopy<...Diagnosis of Acanthamoeba keratitis in vivo with confocal microscopy<...
The Acanthamoeba organisms in the human corneas were identical in size and shape to Acanthamoeba organisms on an agar plate ... The Acanthamoeba organisms in the human corneas were identical in size and shape to Acanthamoeba organisms on an agar plate ... The Acanthamoeba organisms in the human corneas were identical in size and shape to Acanthamoeba organisms on an agar plate ... The Acanthamoeba organisms in the human corneas were identical in size and shape to Acanthamoeba organisms on an agar plate ...
https://ohsu.pure.elsevier.com/en/publications/diagnosis-of-acanthamoeba-keratitis-in-vivo-with-confocal-microsc-2
In vitro activity of 1H-phenalen-1-one derivatives against Acanthamoeba castellanii Neff and their mechanisms of cell death |...In vitro activity of 1H-phenalen-1-one derivatives against Acanthamoeba castellanii Neff and their mechanisms of cell death |...
In vitro activity of 1H-phenalen-1-one derivatives against Acanthamoeba castellanii Neff and their mechanisms of cell death * ...
https://portalciencia.ull.es/documentos/5e3c3c9329995246bbf6084e
Accommodative dysfunction | AOAAccommodative dysfunction | AOA
Acanthamoeba Acanthamoeba is one of the most common organisms in the environment. Although it rarely causes infection, when it ...
https://www.aoa.org/healthy-eyes/eye-and-vision-conditions/accommodative-dysfunction?sso=y
Coinfections Common in Acanthamoeba Cases
... Risk expands beyond contact lens use.. Acanthamoeba often goes hand-in-hand with ... In an effort to find the incidence of Acanthamoeba keratitis and the coexistence of Acanthamoeba and fungi in microbial ... since both are frequently associated with Acanthamoeba keratitis and Acanthamoeba coinfections. Investigators found ring ... Out of 401 cases, the study found 40 patients-or 10%-were positive for Acanthamoeba, and 16 of the 40 tested positive for both ...
https://stage.reviewofoptometry.com/news/article/coinfections-common-in-acanthamoeba-cases
Meningitis Differential DiagnosesMeningitis Differential Diagnoses
El Sahly H, Udayamurthy M, Parkerson G, Hasbun R. Survival of an AIDS patient after infection with Acanthamoeba sp. of the ...
https://www.medscape.com/answers/232915-13491/what-are-the-differential-diagnoses-for-meningitis
Corneal ulcers and infections: MedlinePlus Medical EncyclopediaCorneal ulcers and infections: MedlinePlus Medical Encyclopedia
Acanthamoeba keratitis occurs in contact lens users. It is more likely to happen in people who make their own homemade cleaning ...
https://medlineplus.gov/ency/article/001032.htm
ACANTHAMOEBA KERATITIS IN A HARD CONTACT-LENSACANTHAMOEBA KERATITIS IN A HARD CONTACT-LENS
JavaScript is disabled for your browser. Some features of this site may not work without it ...
https://oparu.uni-ulm.de/xmlui/handle/123456789/9356

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Basics of Parasitic/Amebic Keratitis | Contact Lenses | CDC
Basics of Parasitic/Amebic Keratitis | Contact Lenses | CDC (cdc.gov)
Acanthamoeba Keratitis --- Multiple States, 2005--2007
Acanthamoeba Keratitis --- Multiple States, 2005--2007 (cdc.gov)
Acanthamoeba Keratitis Multiple States, 2005--2007
Acanthamoeba Keratitis Multiple States, 2005--2007 (cdc.gov)
Figure 1 - Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine - Volume 14, Number 11-November...
Figure 1 - Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine - Volume 14, Number 11-November... (wwwnc.cdc.gov)
Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine - Volume 14, Number 11-November 2008 -...
Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine - Volume 14, Number 11-November 2008 -... (wwwnc.cdc.gov)
Figure 2 - Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine - Volume 14, Number 11-November...
Figure 2 - Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine - Volume 14, Number 11-November... (wwwnc.cdc.gov)
DHS Search Results | Wisconsin Department of Health Services
DHS Search Results | Wisconsin Department of Health Services (dhs.wisconsin.gov)
Figure 2 - Rapidly Fatal Acanthamoeba Encephalitis and Treatment of Cryoglobulinemia - Volume 13, Number 3-March 2007 -...
Figure 2 - Rapidly Fatal Acanthamoeba Encephalitis and Treatment of Cryoglobulinemia - Volume 13, Number 3-March 2007 -... (wwwnc.cdc.gov)
Rapidly Fatal Acanthamoeba Encephalitis and Treatment of Cryoglobulinemia - Volume 13, Number 3-March 2007 - Emerging...
Rapidly Fatal Acanthamoeba Encephalitis and Treatment of Cryoglobulinemia - Volume 13, Number 3-March 2007 - Emerging... (wwwnc.cdc.gov)
Figure - Parachlamydia acanthamoebae Infection and Abortion in Small Ruminants - Volume 14, Number 12-December 2008 - Emerging...
Figure - Parachlamydia acanthamoebae Infection and Abortion in Small Ruminants - Volume 14, Number 12-December 2008 - Emerging... (wwwnc.cdc.gov)
Figure 1 - Rapidly Fatal Acanthamoeba Encephalitis and Treatment of Cryoglobulinemia - Volume 13, Number 3-March 2007 -...
Figure 1 - Rapidly Fatal Acanthamoeba Encephalitis and Treatment of Cryoglobulinemia - Volume 13, Number 3-March 2007 -... (wwwnc.cdc.gov)
Figure 1 - Acanthamoeba Encephalitis in Patient with Systemic Lupus, India - Volume 12, Number 6-June 2006 - Emerging...
Figure 1 - Acanthamoeba Encephalitis in Patient with Systemic Lupus, India - Volume 12, Number 6-June 2006 - Emerging... (wwwnc.cdc.gov)
Figure 2 - Acanthamoeba Encephalitis in Patient with Systemic Lupus, India - Volume 12, Number 6-June 2006 - Emerging...
Figure 2 - Acanthamoeba Encephalitis in Patient with Systemic Lupus, India - Volume 12, Number 6-June 2006 - Emerging... (wwwnc.cdc.gov)
2015 Waterborne Disease Outbreaks Annual Surveillance Report | Water-related Topics | Healthy Water | CDC
2015 Waterborne Disease Outbreaks Annual Surveillance Report | Water-related Topics | Healthy Water | CDC (cdc.gov)
Outbreaks Associated with Treated Recreational Water - United States, 2015-2019 | MMWR
Outbreaks Associated with Treated Recreational Water - United States, 2015-2019 | MMWR (cdc.gov)
Figure - Fatal Disseminated Acanthamoeba lenticulata Acanthamebiasis in a Heart Transplant Patient - Volume 13, Number 5-May...
Figure - Fatal Disseminated Acanthamoeba lenticulata Acanthamebiasis in a Heart Transplant Patient - Volume 13, Number 5-May... (wwwnc.cdc.gov)
Fatal Disseminated Acanthamoeba lenticulata Acanthamebiasis in a Heart Transplant Patient - Volume 13, Number 5-May 2007 -...
Fatal Disseminated Acanthamoeba lenticulata Acanthamebiasis in a Heart Transplant Patient - Volume 13, Number 5-May 2007 -... (wwwnc.cdc.gov)
Balamuthia mandrillaris Transmitted Through Organ Transplantation --- Mississippi, 2009
Balamuthia mandrillaris Transmitted Through Organ Transplantation --- Mississippi, 2009 (cdc.gov)
Prevention & Control | Naegleria fowleri | CDC
Prevention & Control | Naegleria fowleri | CDC (cdc.gov)
Pathogen and Environment | Naegleria fowleri | CDC
Pathogen and Environment | Naegleria fowleri | CDC (cdc.gov)
Information for Public Health & Medical Professionals | Naegleria fowleri | CDC
Information for Public Health & Medical Professionals | Naegleria fowleri | CDC (cdc.gov)
Primary Amebic Meningoencephalitis --- Arizona, Florida, and Texas, 2007
Primary Amebic Meningoencephalitis --- Arizona, Florida, and Texas, 2007 (cdc.gov)
Reduce Risk from Water | HAI | CDC
Reduce Risk from Water | HAI | CDC (cdc.gov)
Case #369 - April 2014
Case #369 - April 2014 (cdc.gov)
Balamuthia</I> Amebic Encephalitis --- California,...
Balamuthia</I> Amebic Encephalitis --- California,... (cdc.gov)