Absorbable Implants: Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.Dental Implants: Biocompatible materials placed into (endosseous) or onto (subperiosteal) the jawbone to support a crown, bridge, or artificial tooth, or to stabilize a diseased tooth.Prostheses and Implants: Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.Drug Implants: Small containers or pellets of a solid drug implanted in the body to achieve sustained release of the drug.Breast Implants: Implants used to reconstruct and/or cosmetically enhance the female breast. They have an outer shell or envelope of silicone elastomer and are filled with either saline or silicone gel. The outer shell may be either smooth or textured.Implants, Experimental: Artificial substitutes for body parts and materials inserted into organisms during experimental studies.Dental Implantation, Endosseous: Insertion of an implant into the bone of the mandible or maxilla. The implant has an exposed head which protrudes through the mucosa and is a prosthodontic abutment.Orbital Implants: Rounded objects made of coral, teflon, or alloplastic polymer and covered with sclera, and which are implanted in the orbit following enucleation. An artificial eye (EYE, ARTIFICIAL) is usually attached to the anterior of the orbital implant for cosmetic purposes.Dental Implants, Single-Tooth: Devices, usually alloplastic, surgically inserted into or onto the jawbone, which support a single prosthetic tooth and serve either as abutments or as cosmetic replacements for missing teeth.Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)Dental Prosthesis, Implant-Supported: A prosthesis that gains its support, stability, and retention from a substructure that is implanted under the soft tissues of the basal seat of the device and is in contact with bone. (From Boucher's Clinical Dental Terminology, 4th ed)Cochlear Implantation: Surgical insertion of an electronic hearing device (COCHLEAR IMPLANTS) with electrodes to the COCHLEAR NERVE in the inner ear to create sound sensation in patients with residual nerve fibers.Dental Prosthesis Design: The plan and delineation of dental prostheses in general or a specific dental prosthesis. It does not include DENTURE DESIGN. The framework usually consists of metal.Immediate Dental Implant Loading: Endosseous dental implantation where implants are fitted with an abutment or where an implant with a transmucosal coronal portion is used immediately (within 1 week) after the initial extraction. Conventionally, the implantation is performed in two stages with more than two months in between the stages.Deafness: A general term for the complete loss of the ability to hear from both ears.Dental Abutments: Natural teeth or teeth roots used as anchorage for a fixed or removable denture or other prosthesis (such as an implant) serving the same purpose.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Denture, Overlay: Removable prosthesis constructed over natural teeth or implanted studs.Prosthesis Implantation: Surgical insertion of a prosthesis.Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Dental Prosthesis Retention: Holding a DENTAL PROSTHESIS in place by its design, or by the use of additional devices or adhesives.Molteno Implants: Devices implanted to control intraocular pressure by allowing aqueous fluid to drain from the anterior chamber. (Hoffman, Pocket Glossary of Ophthalmologic Terminology, 1989)Eye, Artificial: A ready-made or custom-made prosthesis of glass or plastic shaped and colored to resemble the anterior portion of a normal eye and used for cosmetic reasons. It is attached to the anterior portion of an orbital implant (ORBITAL IMPLANTS) which is placed in the socket of an enucleated or eviscerated eye. (From Dorland, 28th ed)Foreign-Body Reaction: Chronic inflammation and granuloma formation around irritating foreign bodies.Silicone Gels: Synthetic organosiloxane gels that are formed from synthetic polymers of silicone oxide with organic sidechains (polydimethylsiloxane) by lengthening the polymer chains. Unlike silicone elastomers, they are not treated with amorphous silica. They are used as fillers in breast implants.Trenbolone Acetate: An anabolic steroid used mainly as an anabolic agent in veterinary practice.Jaw, Edentulous, Partially: Absence of teeth from a portion of the mandible and/or maxilla.Silicones: A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Speech Perception: The process whereby an utterance is decoded into a representation in terms of linguistic units (sequences of phonetic segments which combine to form lexical and grammatical morphemes).Dental Restoration Failure: Inability or inadequacy of a dental restoration or prosthesis to perform as expected.Implant Capsular Contracture: The shrinkage of the foreign body encapsulation scar tissue that forms around artificial implants imbedded in body tissues.Durapatite: The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.Peri-Implantitis: An inflammatory process with loss of supporting bone in the tissues surrounding functioning DENTAL IMPLANTS.Correction of Hearing Impairment: Procedures for correcting HEARING DISORDERS.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Hip Prosthesis: Replacement for a hip joint.Dental Implant-Abutment Design: The plan and delineation of DENTAL IMPLANT fitting with DENTAL ABUTMENT.Alveolar Ridge Augmentation: Preprosthetic surgery involving rib, cartilage, or iliac crest bone grafts, usually autologous, or synthetic implants for rebuilding the alveolar ridge.Surface Properties: Characteristics or attributes of the outer boundaries of objects, including molecules.Breast Implantation: Surgical insertion of an inert sac filled with silicone or other material to augment the female form cosmetically.Joint Prosthesis: Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Diethylhexyl Phthalate: An ester of phthalic acid. It appears as a light-colored, odorless liquid and is used as a plasticizer for many resins and elastomers.Construction Materials: Supplies used in building.Seals, Earless: The family Phocidae, suborder PINNIPEDIA, order CARNIVORA, comprising the true seals. They lack external ears and are unable to use their hind flippers to walk. It includes over 18 species including the harp seal, probably the best known seal species in the world.Fur Seals: A group comprised of several species of eared seals found in two genera, in the family Otariidae. In comparison to SEA LIONS, they have an especially dense wooly undercoat.Tantalum: Tantalum. A rare metallic element, atomic number 73, atomic weight 180.948, symbol Ta. It is a noncorrosive and malleable metal that has been used for plates or disks to replace cranial defects, for wire sutures, and for making prosthetic devices. (Dorland, 28th ed)Heart: The hollow, muscular organ that maintains the circulation of the blood.Bone Screws: Specialized devices used in ORTHOPEDIC SURGERY to repair bone fractures.Fracture Fixation, Internal: The use of internal devices (metal plates, nails, rods, etc.) to hold the position of a fracture in proper alignment.Bone Plates: Implantable fracture fixation devices attached to bone fragments with screws to bridge the fracture gap and shield the fracture site from stress as bone heals. (UMDNS, 1999)Internal Fixators: Internal devices used in osteosynthesis to hold the position of the fracture in proper alignment. By applying the principles of biomedical engineering, the surgeon uses metal plates, nails, rods, etc., for the correction of skeletal defects.Fracture Healing: The physiological restoration of bone tissue and function after a fracture. It includes BONY CALLUS formation and normal replacement of bone tissue.Animal Testing Alternatives: Procedures, such as TISSUE CULTURE TECHNIQUES; mathematical models; etc., when used or advocated for use in place of the use of animals in research or diagnostic laboratories.Fracture Fixation: The use of metallic devices inserted into or through bone to hold a fracture in a set position and alignment while it heals.

A new strategy for the surgical treatment of aortic coarctation associated with ventricular septal defect in infants using an absorbable pulmonary artery band. (1/490)

OBJECTIVES: We propose a new strategy using coarctation repair together with a polidioxanone absorbable pulmonary artery banding to limit operative risk and to spare infants with aortic coarctation subsequent operations. BACKGROUND: The alternative for the surgical management of aortic coarctation associated with ventricular septal defect (VSD) is single-stage repair versus coarctation repair with or without banding of the pulmonary artery. METHODS: Eleven infants (mean weight 2,560 +/- 1,750 g, range 1,320 to 3,800 g) underwent a coarctation repair with a polydioxanone banding. Seven had a trabecular and four a perimembranous VSD. The mean size of the VSD was 5 +/- 0.7 mm (range 4 to 7 mm). The systolic pulmonary pressure was >80% of the aortic pressure in all. The pulmonary band was tightened until the systolic pulmonary pressure fell below 50% of the aortic pressure. RESULTS: There were no hospital deaths. The reabsorption of the banding was complete after 5.7 months in all patients (3 to 6.5 months). The VSD closed completely in four infants and partially in six, in whom the pulmonary artery pressure was normal without evidence for significant left-to-right shunt. One patient with a large trabecular VSD underwent surgical closure of his defect after four months. Finally, a subsequent open-heart surgery could be avoided in 91% (10/11) of patients. CONCLUSIONS: Provided the VSD belongs to types prone to close spontaneously, this policy may reduce the number of surgical procedures per infant as well as in-hospital mortality and morbidity rates. It should be proposed as an alternative to more complex procedures.  (+info)

Rotational acetabular osteotomy using biodegradable internal fixation. (2/490)

We used biodegradable poly-L-lactide screws in rotational acetabular osteotomy in 41 hips of 41 patients, and studied the complications after an average follow-up of 4.9 years (range 1.0-7.7 years). There were 39 females and 2 males, their average age at the time of the operation was 32 years (range 12-55 years). A small subcutaneous abscess appeared around the non-absorbable sutures in 2 patients after surgery. There was 1 case of thrombophlebitis and 1 of local dermatitis. The small subcutaneous abscess resolved after the removal of the suture material in the 2 cases, and the thrombophlebitis resolved with aspirin. The local dermatitis persisted but was cured by local steroid therapy over 5.8 years. The incidence of local dermatitis after the use of biodegradable implants should be further investigated.  (+info)

Inhibition of neointima formation after experimental coronary artery stenting: a new biodegradable stent coating releasing hirudin and the prostacyclin analogue iloprost. (3/490)

BACKGROUND: To minimize acute stent thrombosis and development of restenosis, stents coated with biodegradable and nonbiodegradable polymers have been proposed to serve as sustained-release drug carriers. METHODS AND RESULTS: In both a sheep and a pig model, we examined the vascular response to standard and high-pressure implantation of coronary Palmaz-Schatz stents coated with a 10-microm layer of polylactic acid (MW 30 kDa) releasing recombinant polyethylene glycol (r-PEG)-hirudin and the prostacyclin analogue iloprost, both drugs with antithrombotic and potentially antiproliferative effects. Study observation time was 28 days. Between the corresponding stent groups, no differences were observed with regard to preplacement and postplacement implantation parameters. The morphometric analysis demonstrated that the coating was associated with a greater lumen diameter through a reduction in the mean restenosis area by 22.9% (P<0.02) in the standard-pressure model (sheep) and by 24.8% (P<0.02) in the overstretch pig model compared with uncoated control stents without inducing a local inflammatory response. CONCLUSIONS: The results from this study demonstrate beneficial effects of a polymeric stent coating with polylactic acid releasing r-PEG-hirudin and iloprost on the development of restenosis after coronary stent placement at 4 weeks, independent of the extent of vascular injury. Future studies are proposed to investigate the integration of other substances to further enhance the potential of the stent coating on reducing neointimal formation.  (+info)

In situ tumor vaccination with interleukin-12-encapsulated biodegradable microspheres: induction of tumor regression and potent antitumor immunity. (4/490)

An alternative technology for the local and sustained delivery of cytokines to tumors for cancer immunotherapy was evaluated and shown here to induce tumor regression, suppression of metastasis, and development of systemic antitumor immunity. Treatment of tumor-bearing BALB/c mice with a single intratumoral injection of biodegradable polylactic acid microspheres loaded with recombinant interleukin-12 (IL-12) promoted complete regression of the primary tumor and prevented the metastatic spread to the lung. Mice that experienced tumor regression after being treated rejected a subsequent challenge with live tumor cells, which indicated the development of systemic antitumor immunity. In situ tumor vaccination, ie., injection of IL-12 microspheres into existing tumors, was superior to vaccination of mice with mixtures of tumor cells (live or irradiated) and IL-12 microspheres in inducing systemic antitumor immunity. The sustained release of IL-12 from the microspheres was superior to bolus injection of free IL-12, and intratumoral delivery of microspheres was more effective than other routes of administration. These studies establish the utility of biodegradable polymer microspheres as a clinically feasible alternative to systemic cytokine therapy and cytokine gene-modified cell vaccines for the treatment of neoplastic disease.  (+info)

Soluble biodegradable polymer-based cytokine gene delivery for cancer treatment. (5/490)

Transgene expression and tumor regression after direct injection of plasmid DNA encoding cytokine genes, such as mIL-12 and mIFN-gamma, remain very low. The objective of this study is to develop nontoxic biodegradable polymer-based cytokine gene delivery systems, which should enhance mIL-12 expression, increasing the likelihood of complete tumor elimination. We synthesized poly[alpha-(4-aminobutyl)-l-glycolic acid] (PAGA), a biodegradable nontoxic polymer, by melting condensation. Plasmids used in this study encoded luciferase (pLuc) and murine interleukin-12 (pmIL-12) genes. PAGA/plasmid complexes were prepared at different (+/-) charge ratios and characterized in terms of particle size, zeta potential, osmolality, surface morphology, and cytotoxicity. Polyplexes prepared by complexing PAGA with pmIL-12 as well as pLuc were used for transfection into cultured CT-26 colon adenocarcinoma cells as well as into CT-26 tumor-bearing BALB/c mice. The in vitro and in vivo transfection efficiency was determined by luciferase assay (for pLuc), enzyme-linked immunosorbent assay (for mIL-12, p70, and p40), and reverse transcriptase-polymerase chain reaction (RT-PCR) (for Luc and mIL-12 p35). PAGA condensed and protected plasmids from nuclease degradation. The mean particle size and zeta potential of the polyplexes prepared in 5% (w/v) glucose at 3:1 (+/-) charge ratio were approximately 100 nm and 20 mV, respectively. The surface characterization of polyplexes as determined by atomic force microscopy showed complete condensation of DNA with an ellipsoidal structure in Z direction. The levels of mIL-12 p40, mIL-12 p70, and mIFN-gamma were significantly higher for PAGA/pmIL-12 complexes compared to that of naked pmIL-12. This is in good agreement with RT-PCR data, which showed significant levels of mIL-12 p35 expression. The PAGA/pmIL-12 complexes did not induce any cytotoxicity in CT-26 cells as evidenced by 3- inverted question mark4, 5-dimethylthiazol-2-yl inverted question mark-2,5-diphenyltetrazolium bromide assay and showed enhanced antitumor activity in vivo compared to naked pmIL-12. PAGA/pmIL-12 complexes are nontoxic and significantly enhance mIL-12 expression at mRNA and protein levels both in vitro and in vivo.  (+info)

Early in vivo experience with tissue-engineered trileaflet heart valves. (6/490)

BACKGROUND: Tissue engineering is a new approach in which techniques are being developed to transplant autologous cells onto biodegradable scaffolds to ultimately form new functional autologous tissue. Workers at our laboratory have focused on tissue engineering of heart valves. The present study was designed to evaluate the implantation of a whole trileaflet tissue-engineered heart valve in the pulmonary position in a lamb model. METHODS AND RESULTS: We constructed a biodegradable and biocompatible trileaflet heart valve scaffold that was fabricated from a porous polyhydroxyalkanoate (pore size 180 to 240 microm; Tepha Inc). Vascular cells were harvested from ovine carotid arteries, expanded in vitro, and seeded onto our heart valve scaffold. With the use of cardiopulmonary bypass, the native pulmonary leaflets were resected, and 2-cm segments of pulmonary artery were replaced by autologous cell-seeded heart valve constructs (n=4). One animal received an acellular valved conduit. No animal received any anticoagulation therapy. Animals were killed at 1, 5, 13, and 17 weeks. Explanted valves were examined histologically with scanning electron microscopy, biochemically, and biomechanically. All animals survived the procedure. The valves showed minimal regurgitation, and valve gradients were <20 mm Hg on echocardiography. The maximum gradient was 10 mm Hg with direct pressures. Macroscopically, the tissue-engineered constructs were covered with tissue, and there was no thrombus formation on any of the specimens. Scanning electron microscopy showed smooth flow surfaces during the follow-up period. Histological examination demonstrated laminated fibrous tissue with predominant glycosaminoglycans as extracellular matrix. 4-Hydroxyproline assays demonstrated an increase in collagen content as a percentage of native pulmonary artery (1 week 45.8%, 17 weeks 116%). DNA assays showed a comparable number of cells in all explanted samples. There was no tissue formation in the acellular control. CONCLUSIONS: Tissue-engineered heart valve scaffolds fabricated from polyhydroxyalkanoates can be used for implantation in the pulmonary position with an appropriate function for 120 days in lambs.  (+info)

Functional living trileaflet heart valves grown in vitro. (7/490)

BACKGROUND: Previous tissue engineering approaches to create heart valves have been limited by the structural immaturity and mechanical properties of the valve constructs. This study used an in vitro pulse duplicator system to provide a biomimetic environment during tissue formation to yield more mature implantable heart valves derived from autologous tissue. METHODS AND RESULTS: Trileaflet heart valves were fabricated from novel bioabsorbable polymers and sequentially seeded with autologous ovine myofibroblasts and endothelial cells. The constructs were grown for 14 days in a pulse duplicator in vitro system under gradually increasing flow and pressure conditions. By use of cardiopulmonary bypass, the native pulmonary leaflets were resected, and the valve constructs were implanted into 6 lambs (weight 19+/-2.8 kg). All animals had uneventful postoperative courses, and the valves were explanted at 1 day and at 4, 6, 8, 16, and 20 weeks. Echocardiography demonstrated mobile functioning leaflets without stenosis, thrombus, or aneurysm up to 20 weeks. Histology (16 and 20 weeks) showed uniform layered cuspal tissue with endothelium. Environmental scanning electron microscopy revealed a confluent smooth valvular surface. Mechanical properties were comparable to those of native tissue at 20 weeks. Complete degradation of the polymers occurred by 8 weeks. Extracellular matrix content (collagen, glycosaminoglycans, and elastin) and DNA content increased to levels of native tissue and higher at 20 weeks. CONCLUSIONS: This study demonstrates in vitro generation of implantable complete living heart valves based on a biomimetic flow culture system. These autologous tissue-engineered valves functioned up to 5 months and resembled normal heart valves in microstructure, mechanical properties, and extracellular matrix formation.  (+info)

Scleral plug of biodegradable polymers containing ganciclovir for experimental cytomegalovirus retinitis. (8/490)

PURPOSE: To evaluate the efficacy of a biodegradable scleral plug containing ganciclovir (GCV) in a rabbit model of human cytomegalovirus (HCMV) retinitis. METHODS: To develop a rabbit model for HCMV retinitis, HCMV solution was injected once into the vitreous cavity of pigmented rabbits. The treated animals were divided into three groups: group A received no treatment, group B was treated once with GCV solution, and group C was treated with a scleral plug containing GCV. Rabbits in group B received an intravitreal injection of GCV solution 1 week after HCMV inoculation. In group C, the scleral plug containing GCV was implanted in the vitreous of the rabbits 1 week after HCMV inoculation. Ophthalmoscopically, vitreoretinal findings in each group were graded from 0+ to 4+ every week for 4 weeks after HCMV injection. RESULTS: Eyes of group A rabbits showed whitish retinal exudates and vitreous opacities 3 days after HCMV inoculation. These materials increased gradually until 3 weeks after HCMV inoculation. Scores for vitreoretinal lesions were significantly lower in eyes of group B rabbits compared with those of group A at 1 week after GCV injection (P < 0.05). However, vitreoretinal inflammation in eyes of group B rabbits increased again thereafter, and no significant difference in inflammation between groups A and B was found 2 weeks after GCV injection. In eyes of group C, scores for vitreoretinal lesions were significantly lower compared with those in both group A and group B at 3 weeks after HCMV inoculation (P < 0.01). CONCLUSIONS: The results demonstrated that sustained release of GCV into the vitreous cavity with biodegradable scleral plugs was effective for the treatment of experimentally induced HCMV retinitis in rabbits.  (+info)

OBJECTIVES: We aim to perform a systematic literature review on all studies reporting the clinical outcomes of the use of bioresorbable scaffolds (BRS) in different settings of coronary artery disease (CAD). BACKGROUND: BRS are designed to provide early support of the vessel wall postangioplasty, deliver antiproliferative agents to prevent excessive hyperplastic healing responses and finally disappear when no longer required. Emerging data have provided evidence of their use in specific clinical scenarios. METHODS: A comprehensive literature search was performed by 2 independent reviewers utilizing MEDLINE, EMBASE, and Cochrane Library databases. The only 2 CE marked BRS: everolimus-eluting Bioresorbable vascular scaffold ABSORB BVS and the myolimus-eluting DESolve Bioresorbable Coronary Scaffold (BCS) System were included. RESULTS: The studies were categorized into: ST elevation myocardial infarction (STEMI), stable CAD, and all-comers group. Thirty-one studies were included; 8 in
TY - GEN. T1 - Tensile and flexural creep behaviour of self-reinforced polypropylene composites prepared by compression and injection molding. AU - Kmetty, Á. AU - Bakonyi, P.. AU - Vas, M. L.. AU - Bárány, T.. PY - 2012. Y1 - 2012. N2 - In this work the creep behavior of self-reinforced polymer composites (SRPC) were investigated. As matrix material olefin based thermoplastic elastomeric (o-TPE), as reinforcement highly oriented polypropylenes were used. The tested self-reinforced composites were prepared by filament winding with subsequent compression molding and injection molding (from new pre-impregnated pre-product material) technique. On the SRPC creep tests were carried out. The tensile and flexural creep tests were performed by universal tensile machine and dynamic mechanical analyzer (DMA) test. The results revealed that the creep behavior of the self-reinforced materials depended on the matrix material and the reinforcement structure. The highest strain was achieved using woven ...
Endosteal fixation of a ligament graft with a bioabsorbable interference screw installed in a retrograde manner in ACL reconstruction. The bioabsorbable interference screw is insert-molded with a length of suture extending from the distal tip of the screw for pulling the interference screw into the joint and into position for retrograde insertion at the top of the tibial tunnel. The interference screw has a cannulation extending partially through the screw from the leading tip. The cannulation is shaped to receive a correspondingly shaped driver. The driver is inserted into the tibial tunnel to engage the screw. By turning the driver, the interference screw is turned into the tibial tunnel in a retrograde manner. Accordingly, interference fixation of the graft near the tibial plateau is provided, thereby eliminating graft abrasion at the tibial plateau tunnel opening.
This review discusses and summarizes the recent developments and advances in the use of biodegradable materials for bone repair purposes. The choice between using degradable and non-degradable devices for orthopedic and maxillofacial applications must be carefully weighed. Traditional biodegradable devices for osteosynthesis have been successful in low or mild load bearing applications. However, continuing research and recent developments in the field of material science has resulted in development of biomaterials with improved strength and mechanical properties. For this purpose, biodegradable materials, including polymers, ceramics and magnesium alloys have attracted much attention for osteologic repair and applications. The next generation of biodegradable materials would benefit from recent knowledge gained regarding cell material interactions, with better control of interfacing between the material and the surrounding bone tissue. The next generations of biodegradable materials for bone repair and
This is the first case in the literature describing the V-stenting technique using ABSORB (Abbott Vascular, Santa Clara, California) bioresorbable everolimus-eluting scaffolds (BVS) for the treatment of a left main coronary artery (LMCA) true bifurcation lesion. A 66-year-old woman presented with symptoms of stable angina. A diagnostic angiogram revealed a significant mid-left anterior descending artery (LAD) lesion. After successful implantation of 2 BVS in the mid-LAD, a control angiogram showed haziness extending from distal LMCA into LAD ostium (Medina 0.1.1), likely representing plaque disruption (Fig. 1-I). Due to the fact that the lesions extended in both the LAD and left circumflex artery, we decided to perform V-stenting. A 3.5 × 12-mm BVS (LMCA-LAD) and a 3.5 × 18-mm BVS (LMCA-left circumflex artery) were simultaneously deployed followed by final kissing-balloon inflation. An excellent final angiographic result was achieved (Fig. 1-III). Post-procedural intravascular ultrasound and ...
Plaster of Paris is employed to form implants as well as a bioresorbable scaffold for implants and bone repair in animals. In bone repair, the plaster is mixed with a non-bioresorbable calcium source,
Mountain View, Calif.-based Amaranth Medical announced a $20 million Series B funding round in support of development of the companys flagship Fortitude bioresorbable scaffold, a device-based treatment for coronary artery disease.. Amaranth plans to use the funds to further progress in clinical trials in hopes of winning CE Mark approval in the European Union, according to a company statement. ...
Ultrasonically Assisted Anchoring of Biodegradable Implants for Chevron Osteotomies - Clinical Evaluation of a Novel Fixation Method
The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Scaffolds for tissue engineering prepared from biocompatible, biodegradable polymer-based, lighter than or light as water microcarriers and designed for cell culturing in vitro in a rotating bioreacto
Self-reinforced poly(ethylene terephthalate) composite laminates were manufactured from fabric using a hot press. Fabric was either allowed to shrink or exposed to stretching during different phases of the manufacturing process. Composite macrostructure, crimp, was investigated and results showed that shrinkage affects fibre crimp more than stretching does. Mechanical tests showed that shrinkage do not significantly affect mechanical properties while stretching fabric by 10% during heating results in 50% increase in tensile stiffness. The lack of correlation between crimp and mechanical properties indicates that mechanical properties for self-reinforced poly(ethylene terephthalate) composites are dominated by their microstructure, molecular orientation, which may be affected by the manufacturing process.. ...
BACKGROUND: The Absorb bioresorbable vascular scaffold (BVS) completely resorbs within 3 years after coronary artery implantation. The safety and effectiveness of BVS through this critical 3-year period have not been characterized.. METHODS: We performed an individual-patient-data pooled meta-analysis of the 4 randomized ABSORB trials in which 3389 patients with coronary artery disease were randomly assigned to everolimus-eluting Absorb BVS (n=2164) or cobalt-chromium everolimus-eluting stents (n=1225). The primary efficacy outcome measure was target lesion failure (cardiac mortality, target vessel myocardial infarction, or ischemia-driven target lesion revascularization), and the primary safety outcome measure was device thrombosis.. RESULTS: BVS compared with cobalt-chromium everolimus-eluting stents resulted in higher 3-year rates of target lesion failure (11.7% versus 8.1%; risk ratio [RR], 1.38; 95% confidence interval [CI], 1.10-1.73; P=0.006), driven by greater target vessel myocardial ...
The absence of clinical restenosis in the first major trial of metallic drug-eluting stents (DES) (1) elicited unbridled enthusiasm among interventional cardiologists. However, it did not take long to realize that, although DES were a marked improvement over bare-metal stents (2), they were not perfect. Specifically, McFadden and et al. (3) reported a new complication in 4 patients, late stent thrombosis occurring after discontinuation of dual antiplatelet therapy (DAPT) (3). Since then, we have learned that target lesion-related failures after 1 year (including restenosis as well as thrombosis) occur at a frequency of 2% to 3% per year for all permanent metallic stents, a rate that may continue for 20 years or longer (4,5). The mechanisms contributing to these stent-related failures are multifactorial and include incomplete endothelialization, persistent inflammation, vessel straightening and compliance mismatch, strut fracture, neoatherosclerosis, and others. Bioresorbable vascular scaffolds ...
This is the first prospective study to evaluate the economic outcomes associated with the use of a bioresorbable scaffold versus a conventional DES among patients undergoing PCI. In this randomized trial involving 2,008 patients with stable and unstable coronary artery disease, we found that the use of the Absorb scaffold was associated with slightly higher procedural costs and index hospitalization costs when compared with the Xience stent. Although the total 1-year costs were also numerically higher in the Absorb group, the cost difference was small (approximately $350/patient) and was not significant. Taken together with clinical outcomes demonstrating statistical noninferiority of the Absorb scaffold to the Xience DES, these findings demonstrate roughly comparable clinical and economic outcomes with these 2 devices within 1 year (assuming a $100 per device price difference). However, these results remain uncertain at present, because the ABSORB III trial was underpowered to exclude small ...
TY - JOUR. T1 - Handedness of Twisted Lamella in Banded Spherulite of Chiral Polylactides and Their Blends. AU - Wang, Hsiao Fang. AU - Chiang, Chen Hung. AU - Hsu, Wen Chun. AU - Wen, Tao. AU - Chuang, Wei Tsung. AU - Lotz, Bernard. AU - Li, Ming Chia. AU - Ho, Rong Ming. PY - 2017/7/25. Y1 - 2017/7/25. N2 - Banded spherulite resulting from lamellar twisting due to the imbalanced stresses at opposite fold surfaces can be formed by isothermal crystallization of chiral polylactide and its blends with poly(ethylene glycol) (PEG). Using a polarized light microscope, the handedness of the twisted lamella in banded spherulite is determined. With the same growth axis along the radial direction as evidenced by wide-angle X-ray diffraction (WAXD) for isothermally crystallized samples at different temperatures, the twisted lamellae of chiral polylactides (poly(l-lactide) (PLLA) and poly(d-lactide) (PDLA)) display opposite handedness. The split-type Cotton effect on the C = O stretching motion of ...
Bioresorbable drug-eluting scaffolding appears to be safe and effective in patients with iliac and femoral artery lesions, based on six-month results in the first-in-man ESPRIT trial presented Jan. 22 at the International Symposium on Endovascular Therapy in Miami Beach, Fla.
The DESappear study is an important milestone in the pursuit of bringing innovative therapies with state-of-the-art bioresorbable technologies to treat a vulnerable population of patients with peripheral arterial disease," said Bosiers. "I am excited to be working with Akesys Medical with the goal to bring this vital product to the clinic.". DESappear investigator Andrew Holden, director of Interventional Services at Auckland City Hospital and associate professor of Radiology at Auckland University School of Medicine, implanted the first Prava in a 66-year-old patient with 45mm of disease in the mid-superficial femoral artery and 80% blockage.. "The diabetic patient with short distance leg claudication demonstrated 0% residual stenosis following the procedure with the Prava scaffold and has recovered well," said Holden. "The Prava scaffolds easy deliverability for treatment and its excellent structural support to the vessel without leaving behind a permanent metallic implant has the potential ...
Novel methods for assessing the electrochemical and micromechanical performance of modular tapers were evaluated, and self-reinforced composite materials were developed for their potential to prevent the onset of mechanically assisted corrosion in modular taper devices. A study of the seating and taper locking mechanics of modular taper samples was conducted, and the effect on taper engagement strength of seating load, loading rate, taper moisture, and taper design/material combination was studied. The load-displacement behavior was captured during seating, and the subsequent pull off load was correlated to seating displacement, seating energy, and seating load. The primary factor affecting taper engagement strength was seating load, and loading rate and design/material factors did not have a significant impact on the quality of the taper engagement. Next, the effect of variation of 7 different design, material, and surgical factors on the fretting corrosion and micromechanical behavior during
Vascular response after coronary angioplasty varies according to the technique. Acute response after balloon angioplasty is characterized by luminal gain in most cases, although dissection can occur during the procedure, putting coronary artery patency at risk. Arterial "elastic recoil" sometimes follows this acute luminal gain, resulting in some degree of restenosis.. Bare-metal stents represented a great advance because they overcame these 2 main limitations of balloon angioplasty. However, vascular damage created by bare-metal stent implantation can result in intense tissue proliferation around the struts, leading to another form of restenosis: proliferative rather than mechanical recoil. Drug-eluting stents (DES) were developed to overcome this limitation by incorporating antiproliferative drugs. First-generation DES changed the post-stenting healing process; however, the lack of coverage of a substantial amount of DES struts was shown to contribute substantially to stent thrombosis ...
Researchers for the DESolve study recommended testing the latest iteration of the device in a larger group of patients, based on results of a first-in-man-study published in the December issue of the Journal of the American College of Cardiology: Cardiovascular Interventions.
Corbion N.V, Evonik Industries Ag, Kls Martin Group, Poly-Med and Foster Corporation are some of the prominent players profiled in MRFR Analysis and are at the forefront of competition in the Global Bioresorbable Polymers Market.. Bioresorbable Polymers Market - Overview. Bioresorbable Polymers are gaining a huge traction over the past decade, owing to its augmented use in the Controlled drug delivery matrix. Get Free Sample Request @ https://www.marketresearchfuture.com/sample_request/969. Consecutively, the global Bioresorbable Polymers Market is exponentially gaining momentum attributed to the burgeoning Healthcare sector. Nowadays, people are inclined towards avoiding surgeries as long as possible and instead prefer controlled drug delivery matrix. Implants made from Bioresorbable Polymers dont need another operation to take implants out. Bioresorbable Polymers get completely biodegraded in the human body without causing any harm minimizing post-surgery risk to the patient and thus ...
This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience ...
Initial Experience of Bioabsorbable Polymer Everolimus-Eluting Synergy Stents in High-Risk Patients Undergoing Complex PCI With Early Discontinuation of Dual-Antiplatelet Therapy
To gain insight into the comparative clinical efficacy of the Orsiro bioabsorbable polymer stent versus an everolimus-eluting durable polymer stent ...
The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substant
Read "Supramolecular structure of polylactides: Influence of the crystallization parameters on the structure of film samples, Russian Journal of Applied Chemistry" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Achievement of final in-scaffold/stent residual stenosis of less than 30% by QCA (by visual estimation if QCA unavailable) with successful delivery and deployment of at least one assigned scaffold/stent at the intended target lesion and successful withdrawal of the delivery system for the target lesion without the occurrence of cardiac death, target vessel MI or repeat TLR during the hospital stay (maximum of 7 days). In dual target lesion setting, both lesions must meet clinical procedure success criteria to have a patient level procedure success.. Acute success (device success and procedure success) was determined based on the device randomized while the Per-Treatment-Evaluable Population (PTE) analysis must be based on the device actually received. Hence, device success and procedure success were provided for the ITT population only. ...
Wykrzykowska et al report a randomized clinical trial of metallic stent v bioresorbable vascular scaffold in routine percutaneous coronary intervention. They found significantly higher risk of device thrombosis with BVS. The editorial is available here. Summary BACKGROUND Bioresorbable vascular scaffolds were developed to overcome the shortcomings of drugeluting stents in percutaneous coronary intervention (PCI). We…
First-of-its-kind medical device, Absorb bioresorbable vascular scaffold opens clogged arteries to restore blood flow, then gradually dissolves in the body.. Loma Linda University Medical Center - Murrieta (LLUMC-Murrieta) announced that it is among the first hospitals in Southern California to begin using fully dissolving stents, a technology designed to restore blood vessels without leaving residual metal behind, as has been the case with conventional metal stents.. The Absorb Bioresorbable Vascular Scaffold stent is a technology manufactured by Abbott Vascular, a division of Abbott Laboratories located in Temecula, CA, just a few miles away from the hospital.. "This is a major milestone for the Cardiac Services program at Loma Linda University Medical Center- Murrieta," said Dr. Niraj V. Parekh, Cath Lab Medical Director. "We are now able to offer patients with coronary artery disease a new treatment option that literally disappears over time.". Dr. Steve Jin, an Interventional Cardiologist ...
While coronary stents have been used to treat CAD since the 1990s, a new stent technology - the SYNERGY Bioabsorbable Polymer Drug-Eluting Stent System - was approved by the U.S. Food and Drug Administration in October 2015, and is the first and only bioabsorbable polymer stent available in the U.S. Unlike traditional drug coated stents that feature permanent polymer coatings known to cause inflammation within the vessels, the SYNERGY stents coating dissolves and disappears after the stents drug has been released. This action enables quick healing of the blood vessel, leaving only the metal part of the stent in the body; ensuring that the blood vessel remains propped open and can deliver blood to the heart for life.. ...
- Clinical Results from 101 Patients Show Low MACE Rate, No Blood Clots and Low Late Loss - In a Sub-Analysis, Nearly All Patients Vessels Assessed for Vasomoto
Bioabsorbable vascular scaffolds are naturally dissolving scaffolds used in the treatment of coronary artery disease (CAD). These are the latest...
In medicine, a stent is any device which is inserted into a blood vessel or other internal duct in order to expand the vessel to prevent or alleviate a blockage. Traditionally, such devices are fabricated from metal mesh and remain in the body permanently or until removed through further surgical intervention. A bioresorbable stent, (also called biodegradable, or naturally-dissolving) serves the same purpose, but is manufactured from a material that may dissolve or be absorbed in the body. The use of metal drug-eluting stents presents some potential drawbacks. These include a predisposition to late stent thrombosis, prevention of late vessel adaptive or expansive remodeling, hindrance of surgical revascularization, and impairment of imaging with multislice CT. To overcome some of these potential drawbacks, several companies are pursuing the development of bioresorbable or bioabsorbable stents. Like metal stents, placement of a bioresorbable stent will restore blood flow and support the vessel ...
Drug-eluting stents (DES) have reached a high safety and efficacy profile, becoming the best option for percutaneous coronary interventions (PCI) based revascularization. However, despite their optimal performance, a few concerns remain regarding their use, mainly due to permanent caging of the vessels and its consequences, first of all late stent thrombosis (ST). Bioresorbable scaffolds (BRS) aim to overcome these issues. The results achieved in randomized controlled trials (RCT) by the first generation of poly-L-lactic acid (PLLA) based scaffolds were promising at 1 year, but the first long term reports (albeit flawed by non-optimal implantation technique) have been disappointing, showing, for instance, an increased risk of ST and target vessel myocardial infarction (TV-MI ...
Summary. GlobalDatas Medical Devices sector report, Bioabsorbable Stents - Medical Devices Pipeline Assessment, 2015″ provides an overview of Bioabsorbable Stents currently in pipeline stage.. The report provides comprehensive information on the pipeline products with comparative analysis of the products at various stages of development. The report reviews major players involved in the pipeline product development. It also provides information about clinical trials in progress, which includes trial phase, trial status, trial start and end dates, and, the number of trials for the key Bioabsorbable Stents pipeline products.. Browse Full Report With TOC at ...
Summary. GlobalDatas Medical Devices sector report, Bioabsorbable Stents - Medical Devices Pipeline Assessment, 2015″ provides an overview of Bioabsorbable Stents currently in pipeline stage.. The report provides comprehensive information on the pipeline products with comparative analysis of the products at various stages of development. The report reviews major players involved in the pipeline product development. It also provides information about clinical trials in progress, which includes trial phase, trial status, trial start and end dates, and, the number of trials for the key Bioabsorbable Stents pipeline products.. Browse Full Report With TOC at ...
A biodegradable, bioabsorbable medical device with a coating for capturing progenitor endothelial cells in vivo and delivering a therapeutic agent at the site of implantation. The coating on the medical device is provided with a biabsorbable polymer composition such as a bioabsorbable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive for controlling the rate of delivery of the therapeutic agent.
Improved aerodynamically light particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the aerodynamically light particles are made of biodegradable material and have a tap density of less than 0.4 g/cm3 and a mass mean diameter between 5 μm and 30 μm. The particles may be formed of biodegradable materials such as biodegradable polymers. For example, the particles may be formed of a functionalized polyester graft copolymer consisting of a linear α-hydroxy-acid polyester backbone having at least one amino acid group incorporated therein and at least one poly(amino acid) side chain extending from an amino acid group in the polyester backbone. In one embodiment, aerodynamically light particles having a large mean diameter, for example greater than 5 μm, can be used for enhanced delivery of a therapeutic agent to the alveolar region of the lung. The aerodynamically light particles incorporating a therapeutic agent
Improved aerodynamically light particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the aerodynamically light particles are made of biodegradable material and have a tap density of less than 0.4 g/cm 3 and a mass mean diameter between 5 μm and 30 μm. The particles may be formed of biodegradable materials such as biodegradable polymers. For example, the particles may be formed of a functionalized polyester graft copolymer consisting of a linear α-hydroxy-acid polyester backbone having at least one amino acid group incorporated therein and at least one poly(amino acid) side chain extending from an amino acid group in the polyester backbone. In one embodiment, aerodynamically light particles having a large mean diameter, for example greater than 5 μm, can be used for enhanced delivery of a therapeutic agent to the alveolar region of the lung. The aerodynamically light particles incorporating a therapeutic
The hose of the present invention comprises an all plastic multilayer hose having a reinforcement therein which is of a material which is flexible and stiff under normal working conditions and which has a flow temperature less than the flow temperature of the cover and liner layers and which forms spaced reinforcing elements incident to the manufacture of the hose. The present invention contemplates use of an apparatus and simplified method which permits the reinforced hose to be readily manufactured in predetermined lengths or continuously so as to provide a hose of indefinite lengths.
It is also one of the main competitors of polystyrene and polypropylene to manufacture packaging products and disposable tableware.. TPU scientists are convinced that the emergence of a simple and cheaper technology of monomer production in Russia will ensure the development of a strong national market of biodegradable polymers. It also provides the cheaper manufacturing of biodegradable implants and other medical devices compared to the foreign ones.. The developers say that if Russian manufacturers are interested in introducing the technology, it is possible to open a pilot industrial production of biodegradable plastics in 2022.. ...
480 Biomedical focuses on the development of a bioresorbable scaffold for treating occlusive disease in the superficial femoral artery (SFA). Its lead product, SFA scaffold, is a proprietary scaffold and delivery system for use in treating peripheral arterial disease in the SFA. The company was founded in 2011 and is based in Watertown, Massachusetts. ...
Results In total 100 patients underwent PCI with a SYNERGY during the one-year study period. The mean age was 72.3 years (10.0; range 41-92 years), 37% of the cohort was defined as elderly (age ,75 years) and 8% defined as very elderly (age ,85 years). Mean EuroSCORE was 11.37 (11.13, range 0.88-70.23). The indication for SYNERGY stent use was as follows; frail or elderly (16%), concurrent anticoagulation (28%) need for a non-cardiac procedure (10%), increased bleeding risk (31%), or other (15%). NSTEMI/STEMI was the presenting complaint in 32% of patients. The coronary disease was complex. Left main stem was involved in (13%), multi-vessel disease (36%), bifurcation disease requiring side-branch stenting (9%), and 37% required CTO intervention. Mean Syntax score was 22.7 (12.1, range 6-53). The mean stent length/ patient was 75.3 mm (41.5) with 1.44 (0.64) lesions treated and 2.67 (1.33) stents implanted per patient. DAPT discontinuation by 3 months has occurred in 52% to date (planned in ...
There is an ongoing clinical need for tissue-engineered small-diameter (,6 mm) vascular grafts since clinical applications are restricted by the limited availability of autologous living grafts or the lack of suitability of synthetic grafts. The present study uses our self-assembly approach to produce a fibroblast-derived decellularized vascular scaffold that can then be available off-the-shelf. Briefly, scaffolds were produced using human dermal fibroblasts sheets rolled around a mandrel, maintained in culture to allow for the formation of cohesive and three-dimensional tubular constructs, and then decellularized by immersion in deionized water. Constructs were then endothelialized and perfused for 1 week in an appropriate bioreactor. Mechanical testing results showed that the decellularization process did not influence the resistance of the tissue and an increase in ultimate tensile strength was observed following the perfusion of the construct in the bioreactor. These fibroblast-derived ...
This patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results.
Barchart.com Inc. is the leading provider of real-time or delayed intraday stock and commodities charts and quotes. Keep tabs on your portfolio, search for stocks, commodities, or mutual funds with screeners, customizable chart indicators and technical analysis.
Future Market Insights on Global Bioabsorbable Stents Market Future Market Insights recently published a fully researched publication on "Global Bioabsorbable Stents Market: Industry analysis (2012-2016) and Opportunity Analysis (2017-2022)", which...
The FDA does not approve of any food item or drug until it has verified everything regarding its safety for human consumption. Today, it has given the go-ahead signal for the first-ever absorbable stent. It will come in handy in the treatment of coronary artery disease.. Get the Free Tracker App to find a Luvabella in Stock. Termed the Absorb GT1 Bioresorbable Vascular Scaffold System (BVS), it gives off the drug everolimus which retards the formation of scar tissue. Also the stent is absorbed by the body slowly and steadily over the course of three years. This approval by the FDA is of great significance since the absorbable stent is a novel treatment method for people who are ideal candidates for angioplasty.. The fact that the stent is absorbable means that those individuals who fear the interventionist scheme of having a foreign metal stent in their bodies would prefer this new method of prophylaxis.. Coronary heart disease (CHD) claims as many as 370,000 lives every year in the United ...
BARCELONA, Spain, May 20, 2009 - Six months outcome of Sahajanand Medical Technologies Supralimus-Sirolimus Eluting stent with Bioabsorbable Polymer was presented at EuroPCR 2009. This analysis was performed as a part of the prospective of E-Series Multicenter Registry. The dataset demonstrates excellent results in high risk patients with complex coronary lesions, including high procedural success rate (> 97%), and sustained safety.. Presented by Dr. Ricardo A. Costa, of Cardiovascular Research Center, Brazil, Preliminary clinical results at 6 months (60%) from Multicenter E-Series Registry demonstrate clinical effectiveness of Supralimus in preventing revascularization, with only 2% TVR (Target Vessel Revascularization) rate. There were no thrombosis events and no TVR/TLR in the Supralimus treated patients in-Hospital. The stent thrombosis rate (definite/probable, ARC) up to 6 months was less than 1%.. Out-of Hospital adverse events (N=718) included only 2% Cardiac Death, 0.5% MI (Myocardial ...
This study is investigating the effect of everolimus drug-eluting stent [Xience Prime] versus everolimus bioresorbable vascular scaffold [Absorb] on vasomotor
An entirely absorbable implant is currently under development.. *^ Kleinman HK, Luckenbill-Edds L, Cannon FW, Sephel GC ( ...
"Evaluation of absorbable poly(ortho esters) for use in surgical implants", J. Appl. Biomaterials 5 (1): pp. 51-64, doi:10.1002/ ... Such drug implants are particularly suitable for applications on the eye, where no sudden release occurs by diffusion (initial ... Implants made of polyorthoester type IV show surface erosion while being highly biocompatible with degradation times from days ... Polyorthoesters are used as hydrophobic implant materials for drug depots for continuous drug delivery by surface erosion. The ...
"Improved postoperative outcome of segmental fasciectomy in Dupuytren disease by insertion of an absorbable cellulose implant". ... After the excision and a careful hemostasis, the cellulose implant is placed in a single layer in between the remaining parts ... The same procedure is used in the segmental fasciectomy with cellulose implant. ...
Different materials, such as synthetic graft materials, xenografts, fibrin glue, synthetic absorbable implant and acrylic ... implant denture, removal of a large cyst or resection of large tumour involving maxilla, development of tumour causing bone ...
Schwarz F, Olivier W, Herten M, Sager M, Chaker A, Becker J. "Influence of implant bed preparation using an Er:YAG laser on the ... Er:YAG lasers can be used in laser aided cataract surgery but owing to its water absorbable nature Nd:YAG is preferred more. ... Bone surgery applications have been found in oral surgery, dentistry, implant dentistry, and otolaryngology. Er:YAG lasers are ... osseointegration of titanium implants: a histomorphometrical study in dogs". J. Oral Rehabil. 2007;34:273-281. Lewandrowski KU ...
... development and marketing of highly innovative bio-absorbable metal implants, i.e. a second surgery to remove implants would no ...
In development are stents with biocompatible surface coatings which do not elute drugs, and also absorbable stents (metal or ... Guidelines recommend a stress test before implanting stents, but most patients do not receive a stress test. While ... In addition to intervascular stents he also developed the first stent-supported porcine valve that can be implanted ...
The OSI incorporates Bio-absorbable implants for sports medicine surgery- These are usually constructed of plastic and are ...
The portion of traditional bone wax which departs the implant site is most likely carried away through the action of the ... Modern day bone wax is commercially available in substantially non-absorbable formulations similar to Horsley's original ... Hemasorb Resorbable Hemostatic Bone Putty is a sterile, soft, moldable, biocompatible, absorbable material of putty-like ... composition, as well as in absorbable/resorbable formats. Most of these waxes are available as a firm wax in stick form that ...
... absorbable implants MeSH E07.695.050 --- artificial limbs MeSH E07.695.075 --- auditory brain stem implant MeSH E07.695.100 ... implanted MeSH E07.296.319.074 --- auditory brain stem implants MeSH E07.296.319.150 --- cochlear implants MeSH E07.296.319.175 ... dental implants MeSH E07.695.185.185 --- dental implants, single-tooth MeSH E07.695.190 --- dental prosthesis MeSH E07.695. ... auditory brain stem implant MeSH E07.814.458.150 --- cochlear implants MeSH E07.858.082 --- artificial organs MeSH E07.858. ...
The aorta is then transplanted onto the pulmonary root, using either absorbable or permanent continuous suture. The aortic ... the circumflex coronary artery will be distorted if the pair are not implanted higher than normal on the neo-aorta, and in some ... and a continuous absorbable suture is then used to anastomose each coronary "button" into the prepared space. In most cases, ... cases they may need to be implanted above the aortic commissure, on the native aorta itself. The circumflex coronary artery may ...
Motoyama S, Laoag-Fernandez JB, Mochizuki S, Yamabe S, Maruo T (May 2003). "Vaginoplasty with Interceed absorbable adhesion ... Handelsman DJ, Conway AJ, Boylan LM (November 1992). "Suppression of human spermatogenesis by testosterone implants". J. Clin. ... Jackson ND, Rosenblatt PL (December 1994). "Use of Interceed Absorbable Adhesion Barrier for vaginoplasty". Obstet Gynecol. 84 ...
In 1986, Puel and Sigwart implanted the first coronary stent in a human patient. Several trials in the 1990s showed the ... The German company, Biotronik, developed a magnesium absorbable stent and published clinical results in 2007. The first company ... Like all invasive medical procedures, implanting stents in the coronary arteries carries risk. For the newer drug-eluting ... who said that more than half of patients with stable coronary artery disease were implanted with stents without even trying ...
1962 The first synchronous cardiac pacemaker co-developed by Cordis is implanted in a patient. 1970s Cordis introduces the ... 2010 EXOSEAL® an innovative vascular closure device with extravascular bio absorbable plug placement and excellent clinical ...
When the breast implant will be emplaced to a subglandular implant pocket, the hypodermic needle penetrates un-resisted into ... and reinforced with strips of absorbable adhesive tape (butterfly stitches) applied to maintain the wound closed. Post- ... into the implant pocket, or is partially deflated. For the subglandular emplacement of breast implants, the technique is ... and malposition of the breast implant in the implant pocket. Therefore, a mastopexy-augmentation procedure features increased ...
The following year, Biotronik released Orsiro to the market-the world's first hybrid drug-eluting stent with a bio-absorbable ... subscription required) "Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised ... Since its start, more than 19 million BIOTRONIK devices in over 100 countries have been implanted. In 1976, the company moved ... In 2007, Biotronik was given the EuroPCR 2007 Novelty Award for its innovative absorbable metal stents (AMS) by the European ...
Ideally, these implants should be strong enough to survive mechanical loads and actions of whichever body area they become a ... Some types of mesh combine permanent and temporary meshes such as Vipro, which includes both re-absorbable vipryl, made from ... Surgical mesh is implanted to strengthen tissue repair and minimize the rate of recurrence. The surgery can be performed ... Any mesh that is implanted in the pelvic area must be strong enough to withstand these loads. Mesh implantation will naturally ...
Permanent implant brachytherapy is a popular treatment choice for patients with low to intermediate risk features, can be ... A new method to reduce rectal radiation injury in prostate cancer patients involves the use of an absorbable spacer placed ... The risk of exposure to others from men with implanted seeds is generally accepted to be insignificant. However, men are ...
It is technically more difficult than an implant and has more swelling and recovery than a simple chin implant. Also, there is ... The layers of tissue in the knee are stitched together, usually with absorbable sutures. A fall or torque to the leg during the ... As opposed to putting an implant on top of the chin bone to bring it forward, an alternative approach is to cut the chin bone ... It can also be used to lengthen the chin (which is more difficult with an implant) or to shorten or narrow a chin. (which is ...
With surgery (for example native tissue repair, biological graft repair, absorbable and non-absorbable mesh repair, colpopexy, ... "Women Implanted with Transvaginal Mesh Suffer from Painful, Permanent Injuries". Parker Waichman LLP. Retrieved 23 June 2015. ...
Smart, Neil J.; Bloor, Stephen (September 2012). "Durability of biologic implants for use in hernia repair: a review". Surgical ... there exists one synthetic totally absorbable mesh, Tigr Matrix, manufactured by Novus Scientific, on the US market (510(k) ... Removal of the implanted mesh, in combination with bisection of regional nerves, is commonly performed to address such cases.[ ... "No-mesh inguinal hernia repair with continuous absorbable sutures: A dream or reality? (a study of 229 patients)". Saudi ...
showed the in vivo degradation of silk via aqueous 3-D scaffolds implanted into Lewis rats. Enzymes are the means used to ... A special manufacturing process removes the outer sericin coating of the silk, which makes it suitable as non-absorbable ... or lower than collagen and PLA when implant rat MSCs with silk fibroin films in vivo. Thus, appropriate degumming and ... there is no need of surgery in order to remove the scaffold implanted. Wang et al. ...
... cartilage substitutes or as implant materials: L. Bhattacharyya, J. Rohrer, ed. (2012), Appendix 1: DISSOCIATION CONSTANTS (pKa ... "Absorbable polyalkylene diglycolates" ...
"Augmentation procedures for the rehabilitation of deficient edentulous ridges with oral implants". Clin Oral Implants Res. 17 ... Non-absorbable ePTFE membranes are still used clinically on a regular basis, and long-term studies suggest that bones regrown ... Collagen absorbable barrier membranes do not require surgical removal, inhibit migration of epithelial cells, promote the ... An experimental study in a canine model". Clin Oral Implants Res. 15 (4): 435-42. doi:10.1111/j.1600-0501.2004.01029.x. PMID ...
In the United States, 45% of the 250,000 valve replacement procedures performed annually involve a mechanical valve implant. ... Pillai, C. K. S.; Sharma, C. P. (2010). "Review Paper: Absorbable Polymeric Surgical Sutures: Chemistry, Production, Properties ... Pillai CK, Sharma CP (Nov 2010). "Review paper: absorbable polymeric surgical sutures: chemistry, production, properties, ... or may be bioactive with a more interactive functionality such as hydroxy-apatite coated hip implants. Biomaterials are also ...
When the breast implant will be emplaced to a subglandular implant pocket, the hypodermic needle penetrates un-resisted into ... and reinforced with strips of absorbable adhesive tape (butterfly stitches) applied to maintain the wound closed. ... into the implant pocket, or is partially deflated. For the subglandular emplacement of breast implants, the technique is ... and malposition of the breast implant in the implant pocket. Therefore, a mastopexy-augmentation procedure features increased ...
EXTEND is an absorbable synthetic punctal implant that provides occlusion up to three months. It is packaged 20 implants per ... EXTEND is an absorbable synthetic punctal implant that provides occlusion up to three months. It is packaged 20 implants per ... BioScrew® Bio-Absorbable Interference Screws. 9. TwinFix AB Absorbable Suture Anchor. 10. INSTAT Collagen Absorbable Hemostat. ... Surgicel Nu-Knit Absorbable Hemostat. 6. PHANTOM Absorbable Cannulated Interference Screws. 7. ABSOLUTE Absorbable Cannulated ...
... avoiding the need for open-heart surgery or metal implants. ... British scientists have created a novel bio-absorbable implant ... Scientists Create Bio-absorbable Implant to Seal Hole in Heart. by VR Sreeraman on August 13, 2007 at 6:03 PM General Health ... British scientists have created a novel bio-absorbable implant that uses the bodys natural building materials to seal a hole ... During the trials, the new bio-absorbable implant effectively sealed holes in more than 50 patients without causing any side ...
... absorbable, bend testing, bone plates, bone screw, conditioning, dimensions, insertion, pullout, shear, torsion,, ... 17 Standard Specification and Test Methods for Absorbable Plates and Screws for Internal Fixation Implants , ... F2902 Guide for Assessment of Absorbable Polymeric Implants. F3160 Guide for Metallurgical Characterization of Absorbable ... 4.1 Absorbable devices are intended to degrade and absorb over time once they are implanted into the body. This makes a removal ...
Absorbable, open-pored implants minimize these risks. Synthetic bone implants are typically made of ceramics, bioglass or ... Development of Sponge Structure and Casting Conditions for Absorbable Magnesium Bone Implants. ... Development of Sponge Structure and Casting Conditions for Absorbable Magnesium Bone Implants. In: TMS T. (eds) TMS 2017 146th ... In order to adapt the degradation behavior to the bones ingrowth behavior, the implant material has to be alloyed and coated. ...
CEENTA ENT doctors offer the LATERA Absorbable Nasal Implant for patients who suffer from nasal airway obstruction caused by ... CEENTA ENT doctors offer the LATERA Absorbable Nasal Implant for patients who suffer from nasal airway obstruction caused by ... What does the LATERA implant treat, and how does it work?. The implant is designed to treat a collapse of the lateral/side wall ... The implant can be performed by itself under local anesthesia, or the procedure can be done simultaneously with nasal turbinate ...
... 0-9. A. B. C. D. E. F. G. H. ... suppression of spermatogenesis by injectable testosterone undecanoate alone or with levonorgestrel implants in chinese men  ...
Comparison Between Absorbable and Non Absorbable Scleral Implants in Deep Sclerectomy (T-Flux and SK-Gel) - Mid-Term Results ... Comparison Between Absorbable and Non Absorbable Scleral Implants in Deep Sclerectomy (T-Flux and SK-Gel) - Mid-Term Results ... Comparison Between Absorbable and Non Absorbable Scleral Implants in Deep Sclerectomy (T-Flux and SK-Gel) - Mid-Term Results. ... 81 patients received T-Flux implants (group 1) and 35 patients received SK-Gel implants (group 2). Examinations were carried ...
Drug Eluting Absorbable Nasal Implant Devices, Non-Drug Eluting Nasal Implants Devices), By Material Type (Polymer, Carboxy ... Global Absorbable Nasal Implant Devices Market: By Product Type ( ... Absorbable implants are commonly preferred over non-absorbable ... Absorbable Nasal Implant Devices Market. Absorbable nasal implant devices preferred over non-absorbable nasal implant devices ... Absorbable Nasal Implant Devices Market by Product Type (Drug Eluting Absorbable Nasal Implant Devices, Non-Drug Eluting Nasal ...
Recently, good results have been reported for absorbable implants which complement the disadvantages of metal implants. This ... When absorbable implants and screws are used for maxillary fractures, no additional surgery to remove the metal plate is ... Absorbable Implants , Complement System Proteins , Cyanoacrylates , Foreign-Body Reaction , Fractures, Bone , Fractures, ... Open reduction of the bone fragments was performed, after which absorbable implants were accurately molded and fixed by screws ...
These implants are ideal for the transient dry eye associated with LASIK or other ocular surgeries. Extend implants can also be ... Extend Absorbable Synthetic Implants provide occlusion for up to 3 months for patients experiencing short-term dry eye symptoms ... Extend 180 Absorbable Synthetic Implants 0.4mm X 2.0mm Extend Absorbable Synthetic Implants provide occlusion for up to 6 ... Extend 180 Absorbable Synthetic Implants 0.5mm X 2.0mm Extend Absorbable Synthetic Implants provide occlusion for up to 6 ...
Find Quality Implants & Interventional Materials Products, Implants & Interventional Materials Manufacturers, Implants & ... Duzey Surgical Partially Absorbable Composite Mesh PGA/PCL-POLYPROYLENE DUZEY MEDIKAL CIHAZLAR SANAYI TICARET LIMITED SIRKETI ... India-silicone implants , India-orthopaedic implants , Israel-silicone implants , Israel-orthopaedic implants are provided. ... dermal implant e guardian orthopedic implants orthopaedic equipment smd led stent shoulder implants folding stents a ...
The coatings comprise a biologically absorbable poly(ester amide), which is a polymeric product of a reaction between a diol- ... Medical implant. US20110151104 *. 28 Feb 2011. 23 Jun 2011. Advanced Cardiovascular Systems, Inc.. Poly(ester amide)-based drug ... Drug eluting medical implant. US8889172. 30 Apr 2008. 18 Nov 2014. Abbott Cardiovascular Systems Inc.. Amorphous or semi- ... Medical implants. US9067000. 18 Nov 2013. 30 Jun 2015. Abbott Cardiovascular Systems Inc.. End-capped poly(ester amide) ...
Absorbable Implants. *Aneurysm, Dissecting -- WG 580. *Aneurysm, False -- WG 580 *Aortic Aneurysm, Abdominal -- WG 410 ...
Clip for implant deployment device. US9398944. Dec 19, 2012. Jul 26, 2016. Covidien Lp. Lock bar spring and clip for implant ... Absorbable fasteners 10 are preferably made of medical grade absorbable materials, for example, Polyglycolic Acid (PGA) and ... 1 and 2, an absorbable surgical fastener apparatus for connecting objects to body tissue, such as absorbable fastener 10 ... More particularly, the present disclosure relates to an absorbable surgical fastener and apparatus for applying the absorbable ...
Bioerodible articles useful as implants and prostheses having predictable degradation rates. US4938949. 12 Sep 1988. 3 Jul 1990 ... Synthetic absorbable surgical devices of poly-dioxanone. US4130639. 28 Sep 1977. 19 Dec 1978. Ethicon, Inc.. Absorbable ... Coumarin endcapped absorbable polymers. US20030158598. 14 Jan 2003. 21 Aug 2003. Control Delivery Systems, Inc.. System for ... Copolymers of the absorbable polymers of the present invention can be prepared by preparing a pre-polymer under melt ...
Medical implant. US8162816. 7 Mar 2002. 24 Abr 2012. Boston Scientific Scimed, Inc.. System for implanting an implant and ... GB-A-l,008,l93 teaches nonabsorbable fabrics used as surgical implants which are coated with absorbable collagen fibrils for ... System for implanting an implant and method thereof. US8632453. 15 Jul 2008. 21 Ene 2014. Boston Scientific Scimed, Inc.. ... WO 86/00533 discloses surgical composite structures comprising a non-absorbable material made of a fabric of fibers which is ...
Absorbable orthopedic implants. US20050209703 *. Apr 29, 2005. Sep 22, 2005. Fell Barry M. Surgically implantable prosthetic ... Active Implants LLC. Meniscus prosthetic device. US9326863. Jul 29, 2011. May 3, 2016. Active Implants LLC. Meniscus prosthetic ... When implanting the prosthesis 200, it may be necessary to first cut the bridge 216 so that the anterior cruciate ligament 218 ... Implant rehydration packages and methods of use. US20070088438 *. Nov 14, 2006. Apr 19, 2007. Cauthen Iii Joseph C. Spinal disc ...
... specifications and methods of tests for all types of implants, and for the materials both basic and composite used in their ... Standardization in the field of implants for surgery 1) and their required instrumentation, covering terminology, ... Absorbable metal implants. Working group. ISO/TC 150/WG 14 Models of tissues for mechanical testing of implants. Working group ... Cardiovascular implants and extracorporeal systems. Sub committee. ISO/TC 150/SC 4. Bone and joint replacements. Sub committee ...
... and then to separate the implant from the retention element when the implant has been passed out of the microcatheter and into ... The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a ... Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down ... To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been ...
The foot/ankle implant comprises a composite structure having a ceramic component with a macroprosity and a polymer component ... Absorbable ankle fusion device. EP2449985B1. 7 Nov 2011. 3 Aug 2016. Tornier. Orthopaedic reamer for bone preparation, in ... The precision implant 100 a can be used, for example, to correct varus and arch deformities. The precision implant 100 a can be ... the precision implant 100 b is shown implanted into the osteotomy opening 152 between the two bone portions 151 of the medial ...
A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is ... The embodiments of the present post-biopsy cavity treatment implant may be selectively biodegradable and/or bio-absorbable such ... show the implant 1506 as shaped as a right cylinder, the implant 1506 may be molded into most any shape, to accommodate most ... The pre-implanted state of the post-biopsy cavity treatment implant 802 is preferably a state in which the post-biopsy cavity ...
implant, absorbable, (scleral buckling methods) Absorbable implant (scleral buckling met... 886.3300. 2. ...
A layer of the multi-layered implant can also consist of a film. Resorbable and non-resorbable substances are considered as ... A multi-layered implant has at least two layers, of which at least two have a different porosity. A woven or knitted mesh, e.g ... Mesh implant with an interlocking knitted structure. US8329211. 17 May 2010. 11 Dic 2012. Ethicon, Inc.. Reinforced absorbable ... The invention relates to a multi-layered implant.. Conventional, homogeneous implants are implanted into the body during an ...
Development of agent-eluting bio-absorbable scaffold suitable for animal implant. Micro-chip implantation provides a reliable, ... However, the formation of tumors and inflammation at the micro-chip implant sites has been observed in companion animals as ... need for alternative material to coat or encapsulate the micro-chips to control the inflammatory reaction after the implant and ...
The synthetic materials used can be absorbable, non-absorbable or a combination of absorbable and non-absorbable materials. ... More in Hernia Surgical Mesh Implants. Hernia Surgical Mesh Implants: Information for Patients Hernia Surgical Mesh Implants: ... Non-absorbable mesh will remain in the body indefinitely and is considered a permanent implant. It is used to provide permanent ... These animal-derived mesh are absorbable. The majority of tissue used to produce these mesh implants are from a pig (porcine) ...
  • Covered devices are fabricated from one or more hydrolytically degradable polymer (from this point on referred to as "absorbable") resins or resin composites. (astm.org)
  • Comprised of the synthetic absorbable polymer, polydioxanone, the Comfortear® Lacrisolve™ Absorbable Punctum Plugs are medium-term implants designed to be inserted into the canaliculus in order to block tear drainage through the lacrimal drainage system. (send2press.com)
  • Major products used in these procedures include injectables, silicone or polymer implants, energy based equipment such as lasers, ultrasound and radiofrequency devices. (medgadget.com)
  • In polycondensation small molecules are formed (in this case of ethanol), which have to be removed from the equilibrium to achieve the necessary molar mass of the polymer for the use as an implant material. (wikipedia.org)
  • Such drug implants are particularly suitable for applications on the eye, where no sudden release occurs by diffusion (initial burst release) but the release follows the continuous polymer degradation. (wikipedia.org)
  • The outcome can be inadequate tissue strength, which can even lead to complications if the implant consists of a non-resorbable material and thus itself ensures some mechanical stability. (google.es)
  • The vast majority of these implants did their job without causing complications, but since they remained inside the body, there was always a risk. (sfexaminer.com)
  • Major complications can occur, such as the implant - made from the same material as drinks bottles - shrinking or degrading, cutting through organs and tissue and leading to infection . (netdoctor.co.uk)
  • Oroantral communications (OAC) are rare complications in oral surgery, which recognize upper molars extraction as the most common etiologic factor (frequencies between 0.31% and 4.7% after the extraction of upper teeth 1 ), followed by maxillary cysts, tumors, trauma, osteoradionecrosis, flap necrosis and dehiscence following implant failure in atrophied maxilla. (medsci.org)
  • The most common adverse reaction is implant site reaction (51.1%), including complications related to the insertion or removal of the implant ( 6 ). (nih.gov)
  • NEW ORLEANS, LA-Adjunctive use of a fully-absorbable mesh envelope that elutes antimicrobials may be an important tool in reducing infection risk in patients who receive cardiac implantable electronic devices (CIEDs), the WRAP IT study suggests. (tctmd.com)
  • 11. The post-biopsy cavity treatment implant of claim 1 , wherein the core portion further includes at least one of a polyanhydride, PEG, cellulose, a gelatin, a lipid, a polysaccharide, a starch and a polyorthoester. (google.co.uk)
  • 3 . The implant of claim 1 , wherein the at least one tissue fragment is obtained from a connective tissue type selected from the group consisting of cartilage, meniscus, tendon, ligament, dermis, bone, fat, and combinations thereof. (google.se)
  • 4 . The implant of claim 1 , wherein the at least one tissue fragment comprises autogeneic tissue, allogeneic tissue, xenogeneic tissue, and combinations thereof. (google.se)
  • 7 . The implant of claim 6 , wherein the granules comprise an aliphatic polyester selected from the group consisting of homopolymers or copolymers of lactides, glycolides, ε-caprolactone, p-dioxanone (1,4-dioxan-2-one), trimethylene carbonate (1,3-dioxan-2-one), and combinations thereof. (google.se)
  • If they consist of a porous or resorbable material, tissue grows into the pores or in the place of the implant during the healing process and thus forms a new tissue structure. (google.es)
  • With non-resorbable implants having cavities or guiding structures, a physiological cell increase can no longer take place at a specific point in time because the non-resorbable implant does not permit complete regeneration. (google.es)
  • The several layers of the implant according to the invention can consist of various materials, resorbable and non-resorbable, which in turn can be degraded at different speeds. (google.es)
  • In a separate set-up, we connect a sensor to an implanted (but only partially resorbable) data-communication system, proving the principle that there is no need for any percutaneous wiring. (nih.gov)
  • Over the past 20 years, the field of absorbable, or "resorbable," implants has grown. (sfexaminer.com)
  • The coatings comprise a biologically absorbable poly(ester amide), which is a polymeric product of a reaction between a diol-diamine and a dicarboxylic acid. (google.com.au)
  • In April 2016, Stryker announced that they had acquired Stanmore Implants Worldwide Limited for 35.6 million pounds. (openpr.com)
  • The Large-Joint Reconstructive Implants report also illustrates the CAGR values for the historic year 2018, the base year 2018, and the forecast for the year 2020-2026. (openpr.com)
  • Animal models of cochlear implants can advance knowledge of the technological bases of treating permanent sensorineural hearing loss with electrical stimulation. (jove.com)
  • Cochlear implants (CIs) are neuroprosthetic devices that can provide a sense of hearing to deaf people. (jove.com)
  • 6. The implant of claim 1, wherein said plurality of internal voids are dimensioned and configured to be packed with bone graft material and said plurality of posterior windows are dimensioned and configured for visibility and additional packing of bone graft material. (freepatentsonline.com)
  • The principal advantage of the use of autologous bone graft with an expanded polytetrafluoroethylene titanium-reinforced membrane (Gore-Tex ®) to guide the bone regeneration is that it assures a predictable healing and allows a possible following implant-prosthetic rehabilitation. (medsci.org)
  • The results of this pilot study indicate that the insertion of ACS after elevating the Schneiderian membrane, simultaneously with implant placement, can significantly increase the volume of the augmentation. (bvsalud.org)
  • The role of non-resorbed hydroxyapatite remnants for implant placement is unclear and requires further investigation. (biomedsearch.com)
  • Breast augmentation is a surgical procedure in which the size and shape of a woman's breasts are enhanced, usually through the placement of an implant behind each breast. (docshop.com)
  • Breast implants can be placed in pockets made either beneath the pectoral muscle (the submuscular placement method) or in front of the pectoral muscle, immediately behind the breast tissue (the subglandular or submammary placement method). (docshop.com)
  • For a right-maxillary central incisor with localized advanced chronic periodontitis a tooth extraction followed by reconstructive procedures and delayed implant placement was proposed and accepted by the patient. (hindawi.com)
  • This ridge reconstruction technique enabled preserving both hard and soft tissues and counteracting vertical and horizontal bone resorption after tooth extraction and allowed for an ideal three-dimensional implant placement. (hindawi.com)
  • the placement of an early-loaded, Morse taper connection implant in the grafted site was effective to create an excellent clinical aesthetic result and to maintain it along time. (hindawi.com)
  • As such, prior to implant placement, an advanced bone defect needs reconstructive procedures to restore the original anatomy, for a predictable long-term aesthetic outcome [ 6 , 7 ]. (hindawi.com)
  • After the extraction of a severely compromised tooth in the anterior maxilla, a local reduction of the vertical and horizontal dimensions of the alveolar ridge may occur, leaving the patient with insufficient bone to allow implant placement [ 6 - 8 ]. (hindawi.com)
  • In these contexts and following tooth extraction, regenerative techniques have been recommended to allow for ridge augmentation, which improves soft and hard tissue volume for the implant placement [ 11 , 12 ]. (hindawi.com)
  • Patients with partially edentulous maxillae were clinically and radiographically evaluated for implant placement. (ovid.com)
  • The production of microstructured surfaces in magnesium alloys, containing zinc as the major alloying element, in particular in absorbable implants such as. (patents.com)
  • A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. (google.ca)
  • Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. (google.ca)
  • and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. (google.ca)
  • To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site. (google.ca)
  • Upon entering the vascular site, the implant expands in situ substantially to fill the vascular site. (google.ca)
  • A flexible, tubular deployment element is used to pass the implant and the retention element through the microcatheter, and then to separate the implant from the retention element when the implant has been passed out of the microcatheter and into the vascular site. (google.ca)
  • 5. The method of claim 1 wherein the step of providing a vascular implant comprises providing an implant that is visible by imaging techniques used for imaging the vascular site. (google.ca)
  • 6. The method of claim 1 wherein the step of providing a vascular implant comprises molding the vascular implant. (google.ca)
  • expanding the implant within the interior volume of the vascular site. (google.ca)
  • 11. The method of claim 7 wherein the step of expanding the implant comprises expanding the implant to a size approximately the same size as the interior volume of the vascular site. (google.ca)
  • DREAMS, a novel treatment concept designed to eliminate the long-term risks associated with a permanent implant, opens a new area of vascular restoration therapy. (drugs.com)
  • The implant can be performed by itself under local anesthesia, or the procedure can be done simultaneously with nasal turbinate reduction. (ceenta.com)
  • Since 2005, we have performed arthroscopic transosseous rotator cuff repairs without using implants, this procedure being inexpensive and having good clinical outcomes. (ghrnet.org)
  • Large-joint reconstructive implants can be termed as the procedure of repairing the damaged joints of the human body by introducing an implant and reconstructing the structure of the joints that have been damaged. (openpr.com)
  • Check out our Infographic on Breast Augmentation , the procedure, types of implants, and risks. (docshop.com)
  • Single implant is a valid treatment procedure, to restore aesthetics in the anterior maxilla, at least in situations where an adequate bone volume is present [ 3 - 5 ]. (hindawi.com)
  • However, metal implants pose a risk of palpation, protrusion, and foreign body reaction, and they may require an additional operation for removal. (bvsalud.org)
  • Recently, good results have been reported for absorbable implants which complement the disadvantages of metal implants. (bvsalud.org)
  • 5. The post-biopsy cavity treatment implant of claim 1 , wherein the core portion is configured to biodegrade at a first controlled rate and the collagenous shell portion is configured to biodegrade at a second controlled rate that is higher than the first controlled rate when the implant is placed in the biological fluid environment. (google.co.uk)
  • 16. The post-biopsy cavity treatment implant of claim 15 , wherein the internal reservoir is configured to deliver the at least one of dye, pigment and therapeutic agent through elution when the implant is placed in a biological fluid environment. (google.co.uk)
  • The implant is biological and absorbable. (fiercebiotech.com)