Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.
Biocompatible materials placed into (endosseous) or onto (subperiosteal) the jawbone to support a crown, bridge, or artificial tooth, or to stabilize a diseased tooth.
Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.
Small containers or pellets of a solid drug implanted in the body to achieve sustained release of the drug.
Implants used to reconstruct and/or cosmetically enhance the female breast. They have an outer shell or envelope of silicone elastomer and are filled with either saline or silicone gel. The outer shell may be either smooth or textured.
Artificial substitutes for body parts and materials inserted into organisms during experimental studies.
Insertion of an implant into the bone of the mandible or maxilla. The implant has an exposed head which protrudes through the mucosa and is a prosthodontic abutment.
Rounded objects made of coral, teflon, or alloplastic polymer and covered with sclera, and which are implanted in the orbit following enucleation. An artificial eye (EYE, ARTIFICIAL) is usually attached to the anterior of the orbital implant for cosmetic purposes.
Devices, usually alloplastic, surgically inserted into or onto the jawbone, which support a single prosthetic tooth and serve either as abutments or as cosmetic replacements for missing teeth.
A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)
A prosthesis that gains its support, stability, and retention from a substructure that is implanted under the soft tissues of the basal seat of the device and is in contact with bone. (From Boucher's Clinical Dental Terminology, 4th ed)
Surgical insertion of an electronic hearing device (COCHLEAR IMPLANTS) with electrodes to the COCHLEAR NERVE in the inner ear to create sound sensation in patients with residual nerve fibers.
The plan and delineation of dental prostheses in general or a specific dental prosthesis. It does not include DENTURE DESIGN. The framework usually consists of metal.
Endosseous dental implantation where implants are fitted with an abutment or where an implant with a transmucosal coronal portion is used immediately (within 1 week) after the initial extraction. Conventionally, the implantation is performed in two stages with more than two months in between the stages.
A general term for the complete loss of the ability to hear from both ears.
Natural teeth or teeth roots used as anchorage for a fixed or removable denture or other prosthesis (such as an implant) serving the same purpose.
The plan and delineation of prostheses in general or a specific prosthesis.
Removable prosthesis constructed over natural teeth or implanted studs.
Surgical insertion of a prosthesis.
Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
Holding a DENTAL PROSTHESIS in place by its design, or by the use of additional devices or adhesives.
Devices implanted to control intraocular pressure by allowing aqueous fluid to drain from the anterior chamber. (Hoffman, Pocket Glossary of Ophthalmologic Terminology, 1989)
A ready-made or custom-made prosthesis of glass or plastic shaped and colored to resemble the anterior portion of a normal eye and used for cosmetic reasons. It is attached to the anterior portion of an orbital implant (ORBITAL IMPLANTS) which is placed in the socket of an enucleated or eviscerated eye. (From Dorland, 28th ed)
Chronic inflammation and granuloma formation around irritating foreign bodies.
Synthetic organosiloxane gels that are formed from synthetic polymers of silicone oxide with organic sidechains (polydimethylsiloxane) by lengthening the polymer chains. Unlike silicone elastomers, they are not treated with amorphous silica. They are used as fillers in breast implants.
An anabolic steroid used mainly as an anabolic agent in veterinary practice.
Absence of teeth from a portion of the mandible and/or maxilla.
A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
The process whereby an utterance is decoded into a representation in terms of linguistic units (sequences of phonetic segments which combine to form lexical and grammatical morphemes).
Inability or inadequacy of a dental restoration or prosthesis to perform as expected.
The shrinkage of the foreign body encapsulation scar tissue that forms around artificial implants imbedded in body tissues.
The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.
An inflammatory process with loss of supporting bone in the tissues surrounding functioning DENTAL IMPLANTS.
Procedures for correcting HEARING DISORDERS.
The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.
Replacement for a hip joint.
The plan and delineation of DENTAL IMPLANT fitting with DENTAL ABUTMENT.
Preprosthetic surgery involving rib, cartilage, or iliac crest bone grafts, usually autologous, or synthetic implants for rebuilding the alveolar ridge.
Characteristics or attributes of the outer boundaries of objects, including molecules.
Surgical insertion of an inert sac filled with silicone or other material to augment the female form cosmetically.
Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)

A new strategy for the surgical treatment of aortic coarctation associated with ventricular septal defect in infants using an absorbable pulmonary artery band. (1/490)

OBJECTIVES: We propose a new strategy using coarctation repair together with a polidioxanone absorbable pulmonary artery banding to limit operative risk and to spare infants with aortic coarctation subsequent operations. BACKGROUND: The alternative for the surgical management of aortic coarctation associated with ventricular septal defect (VSD) is single-stage repair versus coarctation repair with or without banding of the pulmonary artery. METHODS: Eleven infants (mean weight 2,560 +/- 1,750 g, range 1,320 to 3,800 g) underwent a coarctation repair with a polydioxanone banding. Seven had a trabecular and four a perimembranous VSD. The mean size of the VSD was 5 +/- 0.7 mm (range 4 to 7 mm). The systolic pulmonary pressure was >80% of the aortic pressure in all. The pulmonary band was tightened until the systolic pulmonary pressure fell below 50% of the aortic pressure. RESULTS: There were no hospital deaths. The reabsorption of the banding was complete after 5.7 months in all patients (3 to 6.5 months). The VSD closed completely in four infants and partially in six, in whom the pulmonary artery pressure was normal without evidence for significant left-to-right shunt. One patient with a large trabecular VSD underwent surgical closure of his defect after four months. Finally, a subsequent open-heart surgery could be avoided in 91% (10/11) of patients. CONCLUSIONS: Provided the VSD belongs to types prone to close spontaneously, this policy may reduce the number of surgical procedures per infant as well as in-hospital mortality and morbidity rates. It should be proposed as an alternative to more complex procedures.  (+info)

Rotational acetabular osteotomy using biodegradable internal fixation. (2/490)

We used biodegradable poly-L-lactide screws in rotational acetabular osteotomy in 41 hips of 41 patients, and studied the complications after an average follow-up of 4.9 years (range 1.0-7.7 years). There were 39 females and 2 males, their average age at the time of the operation was 32 years (range 12-55 years). A small subcutaneous abscess appeared around the non-absorbable sutures in 2 patients after surgery. There was 1 case of thrombophlebitis and 1 of local dermatitis. The small subcutaneous abscess resolved after the removal of the suture material in the 2 cases, and the thrombophlebitis resolved with aspirin. The local dermatitis persisted but was cured by local steroid therapy over 5.8 years. The incidence of local dermatitis after the use of biodegradable implants should be further investigated.  (+info)

Inhibition of neointima formation after experimental coronary artery stenting: a new biodegradable stent coating releasing hirudin and the prostacyclin analogue iloprost. (3/490)

BACKGROUND: To minimize acute stent thrombosis and development of restenosis, stents coated with biodegradable and nonbiodegradable polymers have been proposed to serve as sustained-release drug carriers. METHODS AND RESULTS: In both a sheep and a pig model, we examined the vascular response to standard and high-pressure implantation of coronary Palmaz-Schatz stents coated with a 10-microm layer of polylactic acid (MW 30 kDa) releasing recombinant polyethylene glycol (r-PEG)-hirudin and the prostacyclin analogue iloprost, both drugs with antithrombotic and potentially antiproliferative effects. Study observation time was 28 days. Between the corresponding stent groups, no differences were observed with regard to preplacement and postplacement implantation parameters. The morphometric analysis demonstrated that the coating was associated with a greater lumen diameter through a reduction in the mean restenosis area by 22.9% (P<0.02) in the standard-pressure model (sheep) and by 24.8% (P<0.02) in the overstretch pig model compared with uncoated control stents without inducing a local inflammatory response. CONCLUSIONS: The results from this study demonstrate beneficial effects of a polymeric stent coating with polylactic acid releasing r-PEG-hirudin and iloprost on the development of restenosis after coronary stent placement at 4 weeks, independent of the extent of vascular injury. Future studies are proposed to investigate the integration of other substances to further enhance the potential of the stent coating on reducing neointimal formation.  (+info)

In situ tumor vaccination with interleukin-12-encapsulated biodegradable microspheres: induction of tumor regression and potent antitumor immunity. (4/490)

An alternative technology for the local and sustained delivery of cytokines to tumors for cancer immunotherapy was evaluated and shown here to induce tumor regression, suppression of metastasis, and development of systemic antitumor immunity. Treatment of tumor-bearing BALB/c mice with a single intratumoral injection of biodegradable polylactic acid microspheres loaded with recombinant interleukin-12 (IL-12) promoted complete regression of the primary tumor and prevented the metastatic spread to the lung. Mice that experienced tumor regression after being treated rejected a subsequent challenge with live tumor cells, which indicated the development of systemic antitumor immunity. In situ tumor vaccination, ie., injection of IL-12 microspheres into existing tumors, was superior to vaccination of mice with mixtures of tumor cells (live or irradiated) and IL-12 microspheres in inducing systemic antitumor immunity. The sustained release of IL-12 from the microspheres was superior to bolus injection of free IL-12, and intratumoral delivery of microspheres was more effective than other routes of administration. These studies establish the utility of biodegradable polymer microspheres as a clinically feasible alternative to systemic cytokine therapy and cytokine gene-modified cell vaccines for the treatment of neoplastic disease.  (+info)

Soluble biodegradable polymer-based cytokine gene delivery for cancer treatment. (5/490)

Transgene expression and tumor regression after direct injection of plasmid DNA encoding cytokine genes, such as mIL-12 and mIFN-gamma, remain very low. The objective of this study is to develop nontoxic biodegradable polymer-based cytokine gene delivery systems, which should enhance mIL-12 expression, increasing the likelihood of complete tumor elimination. We synthesized poly[alpha-(4-aminobutyl)-l-glycolic acid] (PAGA), a biodegradable nontoxic polymer, by melting condensation. Plasmids used in this study encoded luciferase (pLuc) and murine interleukin-12 (pmIL-12) genes. PAGA/plasmid complexes were prepared at different (+/-) charge ratios and characterized in terms of particle size, zeta potential, osmolality, surface morphology, and cytotoxicity. Polyplexes prepared by complexing PAGA with pmIL-12 as well as pLuc were used for transfection into cultured CT-26 colon adenocarcinoma cells as well as into CT-26 tumor-bearing BALB/c mice. The in vitro and in vivo transfection efficiency was determined by luciferase assay (for pLuc), enzyme-linked immunosorbent assay (for mIL-12, p70, and p40), and reverse transcriptase-polymerase chain reaction (RT-PCR) (for Luc and mIL-12 p35). PAGA condensed and protected plasmids from nuclease degradation. The mean particle size and zeta potential of the polyplexes prepared in 5% (w/v) glucose at 3:1 (+/-) charge ratio were approximately 100 nm and 20 mV, respectively. The surface characterization of polyplexes as determined by atomic force microscopy showed complete condensation of DNA with an ellipsoidal structure in Z direction. The levels of mIL-12 p40, mIL-12 p70, and mIFN-gamma were significantly higher for PAGA/pmIL-12 complexes compared to that of naked pmIL-12. This is in good agreement with RT-PCR data, which showed significant levels of mIL-12 p35 expression. The PAGA/pmIL-12 complexes did not induce any cytotoxicity in CT-26 cells as evidenced by 3- inverted question mark4, 5-dimethylthiazol-2-yl inverted question mark-2,5-diphenyltetrazolium bromide assay and showed enhanced antitumor activity in vivo compared to naked pmIL-12. PAGA/pmIL-12 complexes are nontoxic and significantly enhance mIL-12 expression at mRNA and protein levels both in vitro and in vivo.  (+info)

Early in vivo experience with tissue-engineered trileaflet heart valves. (6/490)

BACKGROUND: Tissue engineering is a new approach in which techniques are being developed to transplant autologous cells onto biodegradable scaffolds to ultimately form new functional autologous tissue. Workers at our laboratory have focused on tissue engineering of heart valves. The present study was designed to evaluate the implantation of a whole trileaflet tissue-engineered heart valve in the pulmonary position in a lamb model. METHODS AND RESULTS: We constructed a biodegradable and biocompatible trileaflet heart valve scaffold that was fabricated from a porous polyhydroxyalkanoate (pore size 180 to 240 microm; Tepha Inc). Vascular cells were harvested from ovine carotid arteries, expanded in vitro, and seeded onto our heart valve scaffold. With the use of cardiopulmonary bypass, the native pulmonary leaflets were resected, and 2-cm segments of pulmonary artery were replaced by autologous cell-seeded heart valve constructs (n=4). One animal received an acellular valved conduit. No animal received any anticoagulation therapy. Animals were killed at 1, 5, 13, and 17 weeks. Explanted valves were examined histologically with scanning electron microscopy, biochemically, and biomechanically. All animals survived the procedure. The valves showed minimal regurgitation, and valve gradients were <20 mm Hg on echocardiography. The maximum gradient was 10 mm Hg with direct pressures. Macroscopically, the tissue-engineered constructs were covered with tissue, and there was no thrombus formation on any of the specimens. Scanning electron microscopy showed smooth flow surfaces during the follow-up period. Histological examination demonstrated laminated fibrous tissue with predominant glycosaminoglycans as extracellular matrix. 4-Hydroxyproline assays demonstrated an increase in collagen content as a percentage of native pulmonary artery (1 week 45.8%, 17 weeks 116%). DNA assays showed a comparable number of cells in all explanted samples. There was no tissue formation in the acellular control. CONCLUSIONS: Tissue-engineered heart valve scaffolds fabricated from polyhydroxyalkanoates can be used for implantation in the pulmonary position with an appropriate function for 120 days in lambs.  (+info)

Functional living trileaflet heart valves grown in vitro. (7/490)

BACKGROUND: Previous tissue engineering approaches to create heart valves have been limited by the structural immaturity and mechanical properties of the valve constructs. This study used an in vitro pulse duplicator system to provide a biomimetic environment during tissue formation to yield more mature implantable heart valves derived from autologous tissue. METHODS AND RESULTS: Trileaflet heart valves were fabricated from novel bioabsorbable polymers and sequentially seeded with autologous ovine myofibroblasts and endothelial cells. The constructs were grown for 14 days in a pulse duplicator in vitro system under gradually increasing flow and pressure conditions. By use of cardiopulmonary bypass, the native pulmonary leaflets were resected, and the valve constructs were implanted into 6 lambs (weight 19+/-2.8 kg). All animals had uneventful postoperative courses, and the valves were explanted at 1 day and at 4, 6, 8, 16, and 20 weeks. Echocardiography demonstrated mobile functioning leaflets without stenosis, thrombus, or aneurysm up to 20 weeks. Histology (16 and 20 weeks) showed uniform layered cuspal tissue with endothelium. Environmental scanning electron microscopy revealed a confluent smooth valvular surface. Mechanical properties were comparable to those of native tissue at 20 weeks. Complete degradation of the polymers occurred by 8 weeks. Extracellular matrix content (collagen, glycosaminoglycans, and elastin) and DNA content increased to levels of native tissue and higher at 20 weeks. CONCLUSIONS: This study demonstrates in vitro generation of implantable complete living heart valves based on a biomimetic flow culture system. These autologous tissue-engineered valves functioned up to 5 months and resembled normal heart valves in microstructure, mechanical properties, and extracellular matrix formation.  (+info)

Scleral plug of biodegradable polymers containing ganciclovir for experimental cytomegalovirus retinitis. (8/490)

PURPOSE: To evaluate the efficacy of a biodegradable scleral plug containing ganciclovir (GCV) in a rabbit model of human cytomegalovirus (HCMV) retinitis. METHODS: To develop a rabbit model for HCMV retinitis, HCMV solution was injected once into the vitreous cavity of pigmented rabbits. The treated animals were divided into three groups: group A received no treatment, group B was treated once with GCV solution, and group C was treated with a scleral plug containing GCV. Rabbits in group B received an intravitreal injection of GCV solution 1 week after HCMV inoculation. In group C, the scleral plug containing GCV was implanted in the vitreous of the rabbits 1 week after HCMV inoculation. Ophthalmoscopically, vitreoretinal findings in each group were graded from 0+ to 4+ every week for 4 weeks after HCMV injection. RESULTS: Eyes of group A rabbits showed whitish retinal exudates and vitreous opacities 3 days after HCMV inoculation. These materials increased gradually until 3 weeks after HCMV inoculation. Scores for vitreoretinal lesions were significantly lower in eyes of group B rabbits compared with those of group A at 1 week after GCV injection (P < 0.05). However, vitreoretinal inflammation in eyes of group B rabbits increased again thereafter, and no significant difference in inflammation between groups A and B was found 2 weeks after GCV injection. In eyes of group C, scores for vitreoretinal lesions were significantly lower compared with those in both group A and group B at 3 weeks after HCMV inoculation (P < 0.01). CONCLUSIONS: The results demonstrated that sustained release of GCV into the vitreous cavity with biodegradable scleral plugs was effective for the treatment of experimentally induced HCMV retinitis in rabbits.  (+info)

Absorbable implants are medical devices that are designed to be absorbed or degraded by the body over time, rather than remaining in the body indefinitely. These implants are typically made from materials such as hydrogels, polymers, and metals that are biodegradable or resorbable, meaning that they can be broken down and absorbed by the body's natural processes. Absorbable implants are used in a variety of medical procedures, including orthopedic surgery, dental surgery, and plastic surgery. They are often used as temporary scaffolds to support tissue growth and healing, and are then gradually absorbed by the body as the tissue becomes stronger and more stable. Examples of absorbable implants include absorbable sutures, which are used to close wounds and incisions, and absorbable screws and plates, which are used to stabilize fractures and other bone injuries. Absorbable mesh implants are also used in plastic surgery to repair soft tissue damage, such as hernias or breast reconstruction. Overall, absorbable implants offer a number of advantages over traditional, non-absorbable implants, including reduced risk of complications, improved patient comfort, and faster recovery times. However, they may not be suitable for all medical procedures, and their use should be carefully considered by medical professionals based on the specific needs of each patient.

Breast implants are medical devices that are used to enhance the size, shape, or contour of a woman's breasts. They are typically made of silicone or saline and are inserted into the breast tissue to create a fuller, more rounded appearance. Breast implants can be used for a variety of reasons, including to increase breast size after weight loss or pregnancy, to correct a breast deformity, or to enhance breast symmetry. They are typically placed during surgery and can be removed or replaced if necessary. It is important to note that breast implants are not without risks and complications, and patients should carefully consider the potential benefits and risks before deciding to undergo breast implant surgery.

Titanium is a metal that is commonly used in the medical field due to its unique properties, such as its high strength-to-weight ratio, corrosion resistance, and biocompatibility. It is often used in medical implants, such as hip and knee replacements, dental implants, and spinal implants, due to its ability to integrate well with the body and its durability. Titanium is also used in surgical instruments and medical equipment, such as pacemakers and defibrillators, due to its resistance to corrosion and its ability to withstand high temperatures. Additionally, titanium is sometimes used in the fabrication of prosthetic limbs and other medical devices.

Cochlear implantation is a surgical procedure that involves the placement of a small electronic device called a cochlear implant into the inner ear (cochlea) of a person with severe to profound hearing loss. The cochlear implant works by bypassing the damaged hair cells in the cochlea and directly stimulating the auditory nerve, which sends signals to the brain that are interpreted as sound. The cochlear implant consists of two main components: an external sound processor and an internal implant. The external sound processor captures sound and converts it into electrical signals, which are then transmitted through a skin-penetrating electrode array to the internal implant. The internal implant is surgically implanted into the cochlea and contains a receiver and an electrode array that stimulates the auditory nerve. Cochlear implantation is a complex procedure that requires specialized training and expertise. It is typically recommended for individuals with severe to profound hearing loss who have not responded to other forms of hearing therapy, such as hearing aids or speech therapy. The success of cochlear implantation depends on a variety of factors, including the severity of the hearing loss, the age at which the implant is received, and the individual's ability to learn and use the device.

Deafness is a medical condition characterized by a partial or complete inability to hear sounds. It can be caused by a variety of factors, including genetic mutations, exposure to loud noises, infections, and aging. In the medical field, deafness is typically classified into two main types: conductive deafness and sensorineural deafness. Conductive deafness occurs when there is a problem with the outer or middle ear that prevents sound waves from reaching the inner ear. Sensorineural deafness, on the other hand, occurs when there is damage to the inner ear or the auditory nerve that transmits sound signals to the brain. Deafness can have a significant impact on a person's quality of life, affecting their ability to communicate, socialize, and participate in daily activities. Treatment options for deafness depend on the underlying cause and severity of the condition. In some cases, hearing aids or cochlear implants may be used to improve hearing, while in other cases, surgery or other medical interventions may be necessary to address the underlying cause of the deafness.

In the medical field, dental abutments refer to the part of a dental implant that is visible in the mouth and serves as the connection between the implant and the dental prosthesis (such as a crown or bridge). Dental abutments are typically made of materials such as titanium or zirconia and are designed to be biocompatible with the surrounding tissue and bone. They are usually screw-shaped and are placed into the implant site after the implant has healed and integrated with the surrounding bone. The dental abutment serves as the anchor for the dental prosthesis, providing stability and support for the artificial tooth or teeth. It also helps to distribute the forces of biting and chewing evenly across the implant and surrounding bone, reducing the risk of implant failure. Overall, dental abutments play a critical role in the success of dental implants and are an important component of modern dental prosthetics.

Prosthesis failure refers to the malfunction or breakdown of a medical device or implant, such as a prosthetic limb, heart valve, or joint replacement, that is intended to replace or support a missing or damaged body part. Prosthesis failure can occur due to a variety of factors, including design flaws, manufacturing defects, inappropriate use or care, or the natural wear and tear of the device over time. Symptoms of prosthesis failure may include pain, swelling, infection, movement restrictions, or the device becoming loose or dislodged. Treatment for prosthesis failure may involve repairing or replacing the device, adjusting the device's fit or function, or administering medications or other therapies to manage symptoms or complications.

A foreign-body reaction is a type of immune response that occurs when the body recognizes a foreign substance, such as a foreign particle or implant, as a threat and mounts an inflammatory response to try to remove it. This response can lead to the formation of scar tissue around the foreign body, which can cause pain, swelling, and other symptoms. In some cases, the foreign body may also cause an infection or other complications. Foreign-body reactions can occur in response to a wide range of foreign substances, including medications, metals, plastics, and biological materials. They are a common occurrence in the medical field and can be managed with a variety of treatments, depending on the specific cause and severity of the reaction.

Silicone gels are a type of medical device that are used in various medical applications, including breast augmentation, scar revision, and hand reconstruction. They are made from silicone, a synthetic polymer that is biocompatible and non-toxic to the human body. Silicone gels are typically used as implants, either as standalone devices or as part of a larger implant system. They are available in a range of shapes, sizes, and textures, and can be customized to meet the specific needs of each patient. In breast augmentation, silicone gels are used to increase the size and shape of the breasts. They are typically placed behind the breast tissue or under the muscle, and can be filled with either a cohesive or non-cohesive silicone gel. In scar revision, silicone gels are used to reduce the appearance of scars. They are applied topically to the scar, and can help to soften and flatten the scar tissue over time. In hand reconstruction, silicone gels are used to restore the appearance and function of the hand. They are typically used in conjunction with other surgical procedures, such as skin grafts or tendon transfers, to help restore the appearance and function of the hand. Overall, silicone gels are a versatile and effective medical device that can be used in a variety of medical applications. They are safe, biocompatible, and can provide long-lasting results.

Trenbolone Acetate is a synthetic anabolic and androgenic steroid that is used in veterinary medicine to promote muscle growth and increase appetite in cattle. It is also used in some countries as a performance-enhancing drug in humans, particularly in bodybuilding and other forms of athletic competition. In the medical field, Trenbolone Acetate is not typically used for therapeutic purposes, as it can have serious side effects and is not approved by regulatory agencies for use in humans. However, it has been used in some research studies to investigate its potential effects on muscle growth and other physiological processes.

In the medical field, "Jaw, Edentulous, Partially" refers to a condition where a person has lost some, but not all, of their teeth in the upper or lower jaw. The term "edentulous" means toothless, so "Jaw, Edentulous, Partially" indicates that the person has some remaining teeth in the jaw. This condition is also known as partial edentulism. Partial edentulism can be caused by a variety of factors, including tooth decay, gum disease, injury, or aging. Treatment options for partial edentulism may include dental implants, bridges, dentures, or a combination of these. The specific treatment plan will depend on the individual's specific needs and the condition of their remaining teeth and gums.

Silicones are a group of synthetic polymers that are widely used in various medical applications due to their unique properties, such as biocompatibility, chemical stability, and thermal stability. They are typically composed of silicon, oxygen, and carbon atoms, and can be further modified to include other elements such as hydrogen, nitrogen, and fluorine. In the medical field, silicones are used in a variety of applications, including: 1. Implants: Silicones are commonly used in medical implants such as breast implants, artificial joints, and heart valves due to their biocompatibility and durability. 2. Wound dressings: Silicones are used in wound dressings due to their ability to prevent bacterial growth and promote healing. 3. Drug delivery systems: Silicones are used in drug delivery systems such as microspheres and nanoparticles to improve the delivery of drugs to specific areas of the body. 4. Medical devices: Silicones are used in medical devices such as catheters, syringes, and endoscopes due to their non-stick properties and ability to reduce friction. 5. Cosmetics: Silicones are used in cosmetics such as lotions, creams, and shampoos due to their ability to provide a smooth and silky texture. Overall, silicones are a versatile and important material in the medical field due to their unique properties and wide range of applications.

Biocompatible materials are materials that are designed to interact with living tissues in a way that is safe and non-toxic. These materials are used in a variety of medical applications, including implants, prosthetics, and drug delivery systems. Biocompatible materials must be able to withstand the harsh conditions of the human body, including exposure to bodily fluids, enzymes, and bacteria. They must also be able to integrate with the surrounding tissue and promote healing, rather than causing inflammation or rejection. Some examples of biocompatible materials include metals such as titanium and stainless steel, polymers such as polyethylene and polypropylene, and ceramics such as hydroxyapatite. These materials are often used in the manufacturing of medical devices and implants, such as hip replacements, dental implants, and pacemakers. It is important to note that while a material may be biocompatible, it may not be suitable for all medical applications. The choice of material depends on a variety of factors, including the intended use of the device, the patient's individual needs and health status, and the specific requirements of the medical procedure.

Implant Capsular Contracture is a condition that occurs after breast augmentation surgery, in which the scar tissue surrounding the breast implant becomes thickened and tight, causing the implant to become hard and distorted. This can cause discomfort, pain, and changes in the shape and appearance of the breast. The severity of capsular contracture can range from mild to severe, with Grade III being the most severe and requiring surgical intervention.

Durapatite is a synthetic bone substitute material that is used in orthopedic and dental surgeries. It is a type of calcium phosphate ceramic that is similar in composition to natural bone and is designed to promote bone growth and regeneration. Durapatite is typically used in procedures such as bone grafting, where it is placed in the body to help fill in gaps or defects in bone tissue. It can also be used as an alternative to autografts (bone taken from the patient's own body) or allografts (bone taken from a donor) in certain cases. Durapatite has several advantages over other bone substitute materials, including its ability to promote bone growth and its biocompatibility with the body. It is also relatively easy to shape and can be customized to fit the specific needs of each patient. Overall, Durapatite is a useful tool for surgeons and dentists who are looking for a safe and effective way to promote bone growth and regeneration in the body.

Peri-implantitis is a condition that affects the tissues surrounding dental implants. It is characterized by inflammation and infection of the gums and bone tissue surrounding the implant, which can lead to bone loss and eventually the failure of the implant. The condition is caused by the buildup of plaque and bacteria on the surface of the implant, which can lead to the formation of biofilms and the release of toxins that damage the surrounding tissues. Peri-implantitis can be treated with a combination of oral hygiene measures, antibiotics, and in some cases, surgical procedures to remove infected tissue and clean the implant surface. Early detection and treatment of peri-implantitis is important to prevent further damage and maintain the long-term success of the implant.

Correction of Hearing Impairment refers to the medical or surgical treatment aimed at improving the ability of an individual with hearing loss to perceive and understand sounds. This can be achieved through a variety of methods, including the use of hearing aids, cochlear implants, and other assistive devices, as well as through surgery to repair or replace damaged structures in the ear. The goal of correction of hearing impairment is to improve the individual's quality of life by allowing them to better communicate and participate in social and educational activities.

Alveolar ridge augmentation is a surgical procedure performed to increase the height and width of the alveolar ridge, which is the bony ridge that forms the roof of the mouth and supports the teeth. This procedure is typically performed to prepare the jawbone for dental implants, to increase the amount of bone available for dental implants, or to improve the aesthetics of the smile. There are several techniques that can be used to perform alveolar ridge augmentation, including bone grafting, which involves taking bone from another part of the body and transplanting it to the alveolar ridge, and guided bone regeneration, which involves using a barrier material to stimulate the growth of new bone. Alveolar ridge augmentation is typically performed under local anesthesia, and recovery time can vary depending on the technique used and the extent of the procedure. It is important to follow your dentist or oral surgeon's post-operative instructions to ensure a successful recovery.

Breast implantation is a surgical procedure in which silicone or saline-filled implants are placed behind the breast tissue or under the chest muscle to enhance the size, shape, or contour of the breasts. The procedure is typically performed to increase breast size after weight loss, pregnancy, or aging, or to correct breast asymmetry. Breast implantation can also be performed for reconstructive purposes after a mastectomy or other breast surgery. The implants can be placed through an incision in the breast fold, armpit, or around the areola. The choice of implant type, size, and placement depends on the patient's individual needs and preferences, as well as the surgeon's expertise and experience.

These materials include absorbable polymers, absorbable bioceramics, and absorbable metals. In this paper, we will provide a ... However, traditional implants made of metal or inert materials are not absorbable, leading to complications that affect ... Absorbable implants in sport medicine and arthroscopic surgery: A narrative review of recent development. ... Absorbable implants in sport medicine and arthroscopic surgery: A narrative review of rece ...
Absorbable Implants. *Aneurysm, Dissecting -- WG 580. *Aneurysm, False -- WG 580 *Aortic Aneurysm, Abdominal -- WG 410 ...
An innovative absorbable coating for the polybutester suture. J Long Term Eff Med Implants. 2001. 11(1-2):41-54. [QxMD MEDLINE ... Biomechanical performance of a braided absorbable suture. J Long Term Eff Med Implants. 1996. 6(3-4):169-79. [QxMD MEDLINE Link ... CAPROSYN*, another major advance in synthetic monofilament absorbable suture. J Long Term Eff Med Implants. 2004. 14(5):359-68 ... Absorbable buried suture. Absorbable buried sutures are used as part of a layered closure in wounds under moderate-to-high ...
... ranging from the fixation and osteointegration of permanent implants to the direct healing and fusion of bones without ... Absorbable Implants* * Animals * Biocompatible Materials / chemistry* * Bone Cements / chemistry* * Calcification, Physiologic ... ranging from the fixation and osteointegration of permanent implants to the direct healing and fusion of bones without ... unlocking the potential for adherence to metallic implants during surrounding bony incorporation. Finally, the bone adhesive is ...
ABSORBABLE IMPLANTS. IMPLANTES ABSORBIBLES. IMPLANTES ORBITÁRIOS. ORBITAL IMPLANTS. IMPLANTES ORBITALES. IMPLANTES PARA ...
MeSH Terms: Absorbable Implants*; Allografts; Animals; Biocompatible Materials/chemical synthesis; Bone Transplantation/ ...
Absorbable Implants Actions. * Search in PubMed * Search in MeSH * Add to Search ...
Absorbable Implants* Actions. * Search in PubMed * Search in MeSH * Add to Search ...
Absorbable Gelatin Dental Sponge ) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and ... When implanted in tissues, GELFOAM Dental Sponges are completely absorbed within four to six weeks without inducing excessive ... Our Gelfoam (absorbable gelatin dental sponge) Side Effects Drug Center provides a comprehensive view of available drug ... Gelfoam Dental Sponge (absorbable gelatin dental sponge) is a medical device indicated in oral and dental surgery as an aid in ...
To close the incision, you can use the absorbable sutures and/or the sterile adhesive surgical strips provided. To improve ... When inserting the implant into the cannula, DO NOT FORCE the implant. If resistance is felt, the implant should be removed and ... The recommended dose of SUPPRELIN LA is one implant every 12 months. Each implant contains 50 mg histrelin acetate. The implant ... Inserting the Implant It is suggested that insertion may be easier if a "pocket" for the implant is first created by blunt ...
See gorgeous before and after photos for correction of breast implant complications animation deformity from Dr. Becker in in ... After image shows following implant removal and reconstruction with absorbable mesh. « Previous Next » ... Correction Of Breast Implant Complications Animation Deformity Gallery. * Correction Of Breast Implant Complications Animation ...
7. A comparison of an absorbable nasal implant versus functional rhinoplasty for nasal obstruction.. Olson MD; Barrera JE. Am J ...
Medical implants, including heart valves, stents, and grafts; artificial joints, ligaments, and tendons; hearing loss implants ... Early testing with absorbable zinc stents have been promising.. Self-sufficient power supply for implantable biomedical devices ... They often are biodegradable, and some are bio-absorbable, meaning they are eliminated gradually from the body after fulfilling ... NIBIB-funded researchers are developing a bio-absorbable zinc stent that harmlessly erodes away over time, minimizing the ...
Group A: The capsule will be implanted and held with a permanent stitch on the white of the eye. The outside of the eye will be ... Group B: Doctors will make a small cut in the eye and place only the absorbable stitches. They will talk like they are doing ... To test if releasing CNTF from a small capsule implanted in the eye helps people with MacTel. ... the implant surgery. They may give a pretend injection.. -All participants will get eyedrops for infection and swelling and ...
If this is the case, a penile prosthesis (implant) is a treatment option that your urologist may suggest. ... The stitches used to close the incision are absorbable, meaning they do not need to be removed and will go away on their own. ... How is the implant placed?. Penile implant placement is often done on an outpatient basis so that you can go home the same day ... What is a penile implant (prosthesis)?. A penile implant is a device that is surgically placed in your penis to allow you to ...
To be implanted to reinforce soft tissue or bone where weakness exists. Intended to be used wherever temporary wound support is ... The absorbable protective film also may help minimize the potential for tissue attachment to the device in case of direct ...
The Latera is an absorbable polymer implant implanted by an otolaryngologist or a plastic surgeon to support the upper and ... Spirox is the owner of a fast-growing technology called the Latera Absorbable Nasal Implant, which was launched commercially ... and 70 percent of them could benefit from a lateral wall intervention using a Latera implant. ...
Implants may also be used to help reshape the skull. The jaws may be wired together to hold the new bone positions in place. To ... Small screws and plates made of titanium or a fixation device made of absorbable material may be used to hold the bones in ...
o New concepts and strategies for self-healing materials, e.g. auto- repair of fatigue cracks in structural implants. MECHANISM ... o New platforms of absorbable materials with controlled strength loss and mass absorption profiles. o Informatics and modeling ... implants or devices. We encourage multidisciplinary partnerships and partnerships between academic and industrial scientists. ... variety of medical devices and implants. In addition, ongoing advances in understanding cell biology, wound healing, and ...
Keywords: ACC Publications, Cardiology Magazine, Aging, Algorithms, Absorbable Implants, Amputation, Anesthesia, Angioplasty, ...
during Implant2,3. Attain Stability Quad™ LV Lead. Learn About ASQ ...
... bupivacaine implant), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation ... Studies conducted demonstrated that commonly used surgical materials (nonabsorbable surgical suture, delayed absorbable ... Implant Administration. Place halved implants into the surgical site dry; avoid contact of implant with liquids before ... Implant may become difficult to move once placed in surgical site and moistened; use care when moving implant after placement ...
ABSORBABLE IMPLANTS. IMPLANTES ABSORBIBLES. IMPLANTES ABSORVÍVEIS. ACIDIC GLYCOSPHINGOLIPIDS. GLICOESFINGOLIPIDOS ACIDICOS. ... ORBITAL IMPLANTS. IMPLANTES ORBITALES. IMPLANTES ORBITÁRIOS. ORGANISMS, TRANSGENIC. ORGANISMOS TRANSGENICOS. ORGANISMOS ... GLAUCOMA DRAINAGE IMPLANTS. IMPLANTES DE DRENAJE DE GLAUCOMA. IMPLANTES PARA DRENAGEM DE GLAUCOMA. ...
Bioabsorbable Implants Biodegradable Implants Implants, Absorbable Public MeSH Note. 99. History Note. 99. Date Established. ... Absorbable Implants Preferred Concept UI. M0029978. Scope Note. Implants constructed of materials designed to be absorbed by ... Absorbable Implants Preferred Term Term UI T060139. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1999). ... Implants, Absorbable Term UI T060138. Date02/25/1998. LexicalTag NON. ThesaurusID NLM (1999). ...
Bioabsorbable Implants Biodegradable Implants Implants, Absorbable Public MeSH Note. 99. History Note. 99. Date Established. ... Absorbable Implants Preferred Concept UI. M0029978. Scope Note. Implants constructed of materials designed to be absorbed by ... Absorbable Implants Preferred Term Term UI T060139. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1999). ... Implants, Absorbable Term UI T060138. Date02/25/1998. LexicalTag NON. ThesaurusID NLM (1999). ...
Absorbable implants for the fixation of fractures. J Bone Joint Surg Am. 1991B; 73(1): 148-53. * Google ...
ABSORBABLE IMPLANTS. IMPLANTES ABSORBIBLES. IMPLANTES ORBITÁRIOS. ORBITAL IMPLANTS. IMPLANTES ORBITALES. IMPLANTES PARA ...
ABSORBABLE IMPLANTS. IMPLANTES ABSORBIBLES. IMPLANTES ABSORVÍVEIS. ACIDIC GLYCOSPHINGOLIPIDS. GLICOESFINGOLIPIDOS ACIDICOS. ... ORBITAL IMPLANTS. IMPLANTES ORBITALES. IMPLANTES ORBITÁRIOS. ORGANISMS, TRANSGENIC. ORGANISMOS TRANSGENICOS. ORGANISMOS ... GLAUCOMA DRAINAGE IMPLANTS. IMPLANTES DE DRENAJE DE GLAUCOMA. IMPLANTES PARA DRENAGEM DE GLAUCOMA. ...
ABSORBABLE IMPLANTS. IMPLANTES ABSORBIBLES. IMPLANTES ORBITÁRIOS. ORBITAL IMPLANTS. IMPLANTES ORBITALES. IMPLANTES PARA ...
  • Absorbable sutures are used, so no stitch removal will be necessary! (ilovelyleback.com)
  • When the sutures are implanted in the subcutaneous tissue, it activates fibroblasts, which stimulates collagen production. (mooipraatjies.com)
  • The soft tissue covering the joint is sutured back together and the incision closed with absorbable sutures. (robertcaglemd.com)
  • Spirox is the owner of a fast-growing technology called the Latera Absorbable Nasal Implant, which was launched commercially last July following regulatory clearance from the U.S. Food and Drug Administration. (startribune.com)
  • The Latera is an absorbable polymer implant implanted by an otolaryngologist or a plastic surgeon to support the upper and lower nasal cartilage in a patient with a nasal airway obstruction. (startribune.com)
  • A joint news release from the companies Friday estimated that about 1 million people in a year in the U.S. get a surgical treatment for nasal obstructions, and 70 percent of them could benefit from a lateral wall intervention using a Latera implant. (startribune.com)
  • If yes, talk to your doctor about options to support your lateral nasal cartilage, which may include the LATERA implant. (bellavistaent.com)
  • Bella Vista ENT is now offering a better option to treat nasal obstruction called LATERA ® , an absorbable nasal implant that provides supports and stabilizes the collapsing lateral nasal cartilage. (bellavistaent.com)
  • Clinical research showed that the LATERA ® implant delivers significant relief from nasal obstruction symptoms. (bellavistaent.com)
  • Watch the video and learn more about Nasal Obstruction, Nasal Valve Collapse and the LATERA ® absorbable nasal implant. (bellavistaent.com)
  • LATERA ® is an absorbable nasal implant used to support the upper and lower cartilage inside the lateral (side) wall of your nose. (mysinusdoctor.com)
  • Other risks related to the LATERA implant included discomfort, infection, reaction to material, and need for device retrieval. (mysinusdoctor.com)
  • SUPPRELIN LA is available as a 50 mg histrelin acetate subcutaneous implant which delivers approximately 65 mcg histrelin acetate per day over 12 months ( 3 ). (nih.gov)
  • SUPPRELIN LA (histrelin acetate) subcutaneous implant is indicated for the treatment of children with central precocious puberty (CPP). (nih.gov)
  • These threads are implanted into the subcutaneous layer of the skin using small needles or cannulas. (foreveryoungmi.com)
  • What is a penile implant (prosthesis)? (oncolink.org)
  • A penile implant is a device that is surgically placed in your penis to allow you to get an erection. (oncolink.org)
  • Inflatable penile implant. (oncolink.org)
  • Penile implant placement is often done on an outpatient basis so that you can go home the same day. (oncolink.org)
  • Penile implant surgery is usually very safe. (oncolink.org)
  • The stitches used to close the incision are absorbable, meaning they do not need to be removed and will go away on their own. (oncolink.org)
  • Bioresorbable bone adhesives have potential to revolutionize the clinical treatment of the human skeletal system, ranging from the fixation and osteointegration of permanent implants to the direct healing and fusion of bones without permanent fixation hardware. (nih.gov)
  • Early surgical fixation initially was complicated by many obstacles, such as infection, poorly conceived implants and techniques, metal allergy, and a limited understanding of the biology and mechanics of fracture healing. (medscape.com)
  • Small screws and plates made of titanium or a fixation device made of absorbable material may be used to hold the bones in place. (medlineplus.gov)
  • Absorbable implants for the fixation of fractures. (bvsalud.org)
  • Implants such as suture anchors , interference screws, and endo-buttons are commonly used in these procedures . (bvsalud.org)
  • MINT PDO, is a sterile, absorbable suture with bi-directional barbs which anchor onto the soft tissue. (facialrejuvenationfl.com)
  • Absorbable implants in sport medicine and arthroscopic surgery: A narrative review of recent development. (bvsalud.org)
  • Gelfoam Dental Sponge (absorbable gelatin dental sponge) is a medical device indicated in oral and dental surgery as an aid in providing hemostasis . (rxlist.com)
  • They will talk like they are doing the implant surgery. (nih.gov)
  • CollaFirm, which develops collagen-based technologies and products for implants and surgical applications, is the latest endeavor for Batra, who until last March spent eight years with Providence-based Davol. (collafirm.com)
  • From 1992 to 1999 Batra oversaw regenerative product development at Integra, where he was involved in researching, developing, and obtaining FDA approval for absorbable collagen surgical products including INTEGRA Artificial Skin, Helitene, and BioMend. (collafirm.com)
  • 7. A comparison of an absorbable nasal implant versus functional rhinoplasty for nasal obstruction. (nih.gov)
  • They often are biodegradable, and some are bio-absorbable, meaning they are eliminated gradually from the body after fulfilling a function. (nih.gov)
  • The model was used to assess the cytotoxicity of five common alloying elements in biodegradable implant materials. (ox.ac.uk)
  • However, traditional implants made of metal or inert materials are not absorbable, leading to complications that affect treatment outcomes. (bvsalud.org)
  • The most common adverse reaction is implant site reaction (51.1%), including complications related to the insertion or removal of the implant ( 6 ). (nih.gov)
  • Group B: Doctors will make a small cut in the eye and place only the absorbable stitches. (nih.gov)
  • Our Gelfoam (absorbable gelatin dental sponge) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • Batra helped Davol develop Bard CollaMend, an all-natural biological implant for tissue repair, and the absorbable collagen hemostatic sponge, Avitene. (collafirm.com)
  • After image shows following implant removal and reconstruction with absorbable mesh. (beckermd.com)
  • Polydioxanone (PDO) is an absorbable material that's been used for years in Asia and Europe. (facialrejuvenationfl.com)
  • Polydioxanone (PDO) threads are thinner-than-hair medical grade absorbable threads that lift and tighten sagging skin tissues. (foreveryoungmi.com)
  • Although the cylinders expand in length and width, the erection that you get with an implant is often smaller than your natural erection before having erectile dysfunction (ED). The erectile bodies in some men do not extend fully into the tip of the penis. (oncolink.org)
  • To address this issue, absorbable materials with excellent mechanical properties, good biocompatibility, and controlled degradation rates have been developed and applied in clinical practice. (bvsalud.org)
  • Most often, Dr. Back prefers to perform a "behind the muscle" breast augmentation utilizing various types of both saline and silicone breast implants. (ilovelyleback.com)
  • 3) work aimed at the development of new strategies and approaches toward design optimization of new biomaterials, implants or devices. (nih.gov)
  • These materials include absorbable polymers , absorbable bioceramics, and absorbable metals . (bvsalud.org)
  • 4,5 During the procedure, Dr. Jourdy carefully determines the proper placement site for the implants to provide for optimal support to reduce collapse of the lateral nasal wall and nasal congestion. (mysinusdoctor.com)
  • Risks included temporary symptoms such as mild bruising and inflammation, awareness of the implant, and mild pain or irritation. (mysinusdoctor.com)
  • In this paper , we will provide a comprehensive summary of these absorbable materials from the perspective of clinicians, and discuss their clinical applications and related research in sport medicine . (bvsalud.org)
  • Implants constructed of materials designed to be absorbed by the body without producing an immune response. (nih.gov)
  • It is one of the safest materials that can be implanted in the body. (facialrejuvenationfl.com)
  • The bone adhesive also demonstrates chemical adhesion to titanium approximately twice that of its adhesion to bone, unlocking the potential for adherence to metallic implants during surrounding bony incorporation. (nih.gov)
  • The absorbable protective film also may help minimize the potential for tissue attachment to the device in case of direct contact with the viscera. (fda.gov)
  • 2017. Absorbable Implant to Treat Nasal Valve Collapse. (bellavistaent.com)
  • San Nicoló M, Stelter K, Sadick H, Bas M, Berghaus A. Absorbable implant to treat nasal valve collapse. (mysinusdoctor.com)
  • Technological advances in penile implants: past, present, future. (oncolink.org)
  • To be implanted to reinforce soft tissue or bone where weakness exists. (fda.gov)
  • Bone cement is placed in the holes and the glenoid implant is inserted. (robertcaglemd.com)
  • An implant does not change the feeling on the skin of the penis. (oncolink.org)
  • Genefill Soft Touch is an absorbable skin implant with a high level of purity. (hamadetrading.com)
  • The implants are then carefully placed under the skin on one or both side. (mysinusdoctor.com)
  • Implant Breakage: Have been observed during implant removal. (nih.gov)
  • The recommended dose of SUPPRELIN LA is one implant every 12 months. (nih.gov)
  • These prosthesis are, therefore, suggested only in cases where there are limitations of manual ability of the patient or there are issues related to the high costs of implant. (medicaltourismitaly.com)
  • This article does not talk about this type of implant. (oncolink.org)
  • Group A: The capsule will be implanted and held with a permanent stitch on the white of the eye. (nih.gov)