Abrus: A plant genus of the family FABACEAE. Members contain ABRIN.Abrin: A toxic lectin from the seeds of jequirity, Abrus precatorius L. Very active poison. Five different proteins have so far been isolated: Abrus agglutinin, the component responsible for: hemagglutinating activity, & abrins a-d, the toxic principals each consisting of two peptide chains are held together by disulfide bonds.Plant Lectins: Protein or glycoprotein substances of plant origin that bind to sugar moieties in cell walls or membranes. Some carbohydrate-metabolizing proteins (ENZYMES) from PLANTS also bind to carbohydrates, however they are not considered lectins. Many plant lectins change the physiology of the membrane of BLOOD CELLS to cause agglutination, mitosis, or other biochemical changes. They may play a role in plant defense mechanisms.Lectins: Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.Seeds: The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.Dictionaries, MedicalGlycyrrhiza: A genus of leguminous herbs or shrubs whose roots yield GLYCYRRHETINIC ACID and its derivative, CARBENOXOLONE.Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Education, Pharmacy, Continuing: Educational programs designed to inform graduate pharmacists of recent advances in their particular field.Famous PersonsInternet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Leishmania donovani: A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals and causes visceral leishmaniasis (LEISHMANIASIS, VISCERAL). The sandfly genera Phlebotomus and Lutzomyia are the vectors.Antiprotozoal Agents: Substances that are destructive to protozoans.Antiparasitic Agents: Drugs used to treat or prevent parasitic infections.Leishmania: A genus of flagellate protozoa comprising several species that are pathogenic for humans. Organisms of this genus have an amastigote and a promastigote stage in their life cycles. As a result of enzymatic studies this single genus has been divided into two subgenera: Leishmania leishmania and Leishmania viannia. Species within the Leishmania leishmania subgenus include: L. aethiopica, L. arabica, L. donovani, L. enrietti, L. gerbilli, L. hertigi, L. infantum, L. major, L. mexicana, and L. tropica. The following species are those that compose the Leishmania viannia subgenus: L. braziliensis, L. guyanensis, L. lainsoni, L. naiffi, and L. shawi.Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.Ribosome Inactivating Proteins, Type 2: Ribosome inactivating proteins consisting of two polypeptide chains, the toxic A subunit and a lectin B subunit, linked by disulfide bridges. The lectin portion binds to cell surfaces and facilitates transport into the ENDOPLASMIC RETICULUM.Cinnamomum camphora: A tree, Cinnamomum camphora (L.) J. Presl, known as the source of CAMPHOR.Plants, Genetically Modified: PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.IndiaShock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.National Institute for Occupational Safety and Health (U.S.): An institute of the CENTERS FOR DISEASE CONTROL AND PREVENTION which is responsible for assuring safe and healthful working conditions and for developing standards of safety and health. Research activities are carried out pertinent to these goals.Ricin: A protein phytotoxin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally.Pulmonary Edema: Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.Disaster Planning: Procedures outlined for the care of casualties and the maintenance of services in disasters.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Intellectual Property: Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)Access to Information: Individual's rights to obtain and use information collected or generated by others.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Confidentiality: The privacy of information and its protection against unauthorized disclosure.Privacy: The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)Licensure: The legal authority or formal permission from authorities to carry on certain activities which by law or regulation require such permission. It may be applied to licensure of institutions as well as individuals.Genetic Privacy: The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.Health Policy: Decisions, usually developed by government policymakers, for determining present and future objectives pertaining to the health care system.Counterfeit Drugs: Drugs manufactured and sold with the intent to misrepresent its origin, authenticity, chemical composition, and or efficacy. Counterfeit drugs may contain inappropriate quantities of ingredients not listed on the label or package. In order to further deceive the consumer, the packaging, container, or labeling, may be inaccurate, incorrect, or fake.Fraud: Exploitation through misrepresentation of the facts or concealment of the purposes of the exploiter.Drugs, Chinese Herbal: Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.China: A country spanning from central Asia to the Pacific Ocean.CambodiaMedicine, Chinese Traditional: A system of traditional medicine which is based on the beliefs and practices of the Chinese culture.Plants, Medicinal: Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.Rectal Prolapse: Protrusion of the rectal mucous membrane through the anus. There are various degrees: incomplete with no displacement of the anal sphincter muscle; complete with displacement of the anal sphincter muscle; complete with no displacement of the anal sphincter muscle but with herniation of the bowel; and internal complete with rectosigmoid or upper rectum intussusception into the lower rectum.Rectocele: Herniation of the RECTUM into the VAGINA.Surgical Stapling: A technique of closing incisions and wounds, or of joining and connecting tissues, in which staples are used as sutures.Plant Poisoning: Poisoning by the ingestion of plants or its leaves, berries, roots or stalks. The manifestations in both humans and animals vary in severity from mild to life threatening. In animals, especially domestic animals, it is usually the result of ingesting moldy or fermented forage.Plant Leaves: Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)Plant Proteins: Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.Plant Roots: The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)Datura stramonium: A plant species of the genus DATURA, family SOLANACEAE, that contains TROPANES and other SOLANACEOUS ALKALOIDS.Aconitum: A plant genus of the family RANUNCULACEAE. Members contain a number of diterpenoid alkaloids including: aconitans, hypaconitine, ACONITINE, jesaconitine, ignavine, napelline, and mesaconitine. The common name of Wolfbane is similar to the common name for ARNICA.Hippomane: A plant genus of the family EUPHORBIACEAE. The trees contain hippomanin A and the latex is a skin irritant.Datura: A plant genus of the family SOLANACEAE. Members contain TROPANES. The common name of trumpet flower is also sometimes used for GELSEMIUM.Mydriasis: Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.

Pulchellin, a highly toxic type 2 ribosome-inactivating protein from Abrus pulchellus. Cloning heterologous expression of A-chain and structural studies. (1/13)

Pulchellin is a type 2 ribosome-inactivating protein isolated from seeds of the Abrus pulchellus tenuiflorus plant. This study aims to obtain active and homogeneous protein for structural and biological studies that will clarify the functional aspects of this toxin. The DNA fragment encoding pulchellin A-chain was cloned and inserted into pGEX-5X to express the recombinant pulchellin A-chain (rPAC) as a fusion protein in Escherichia coli. The deduced amino acid sequence analyses of the rPAC presented a high sequential identity (> 86%) with the A-chain of abrin-c. The ability of the rPAC to depurinate rRNA in yeast ribosome was also demonstrated in vitro. In order to validate the toxic activity we promoted the in vitro association of the rPAC with the recombinant pulchellin binding chain (rPBC). Both chains were incubated in the presence of a reduced/oxidized system, yielding an active heterodimer (rPAB). The rPAB showed an apparent molecular mass of approximately 60 kDa, similar to the native pulchellin. The toxic activities of the rPAB and native pulchellin were compared by intraperitoneal injection of different dilutions into mice. The rPAB was able to kill 50% of the tested mice with doses of 45 microg x kg(-1). Our results indicated that the heterodimer showed toxic activity and a conformational pattern similar to pulchellin. In addition, rPAC produced in this heterologous system might be useful for the preparation of immunoconjugates with potential as a therapeutic agent.  (+info)

Structure-function analysis and insights into the reduced toxicity of Abrus precatorius agglutinin I in relation to abrin. (2/13)

Abrin and agglutinin-I from the seeds of Abrus precatorius are type II ribosome-inactivating proteins that inhibit protein synthesis in eukaryotic cells. The two toxins share a high degree of sequence similarity; however, agglutinin-I is weaker in its activity. We compared the kinetics of protein synthesis inhibition by abrin and agglutinin-I in two different cell lines and found that approximately 200-2000-fold higher concentration of agglutinin-I is needed for the same degree of inhibition. Like abrin, agglutinin-I also induced apoptosis in the cells by triggering the intrinsic mitochondrial pathway, although at higher concentrations as compared with abrin. The reason for the decreased toxicity of agglutinin-I became apparent on the analysis of the crystal structure of agglutinin-I obtained by us in comparison with that of the reported structure of abrin. The overall protein folding of agglutinin-I is similar to that of abrin-a with a single disulfide bond holding the toxic A subunit and the lectin-like B-subunit together, constituting a heterodimer. However, there are significant differences in the secondary structural elements, mostly in the A chain. The substitution of Asn-200 in abrin-a with Pro-199 in agglutinin-I seems to be a major cause for the decreased toxicity of agglutinin-I. This perhaps is not a consequence of any kink formation by a proline residue in the helical segment, as reported by others earlier, but due to fewer interactions that proline can possibly have with the bound substrate.  (+info)

Quantification of L-abrine in human and rat urine: a biomarker for the toxin abrin. (3/13)

Abrin is a toxic protein found in the jequirity seed. L-Abrine (N-methyl-tryptophan) is also found in the jequirity seed and can be used as a biomarker for abrin exposure. Analysis of L-abrine was added to an existing method for quantifying ricinine as a marker for ricin exposure in human urine and analytically validated. Accuracy and reproducibility were enhanced by including a newly synthesized (13)C(1)(2)H(3)-L-abrine internal standard. One-milliliter urine samples were processed using solid-phase extraction prior to a 6-min high-performance liquid chromatography separation. Protonated molecular ions were formed via electrospray ionization in a triple-quadrupole mass spectrometer and quantified via multiple reaction monitoring. Method validation included the characterization of two enriched urine pools, which were used as quality control materials. Endogenous levels of L-abrine were quantified in a reference range of 113 random urine samples at 0.72 +/- 0.51 ng/mL. Urinary concentrations of L-abrine were monitored in an intentional rat exposure study for up to 48 h. Comparing the results from the human reference range and the animal exposure study indicates that this method is suitable for quantifying L-abrine within 24 h post-exposure. Quantification of L-abrine beyond 24 h is limited by rapid excretion of the biomarker and the level of the L-abrine dose.  (+info)

A biophysical elucidation for less toxicity of agglutinin than abrin-a from the seeds of Abrus precatorius in consequence of crystal structure. (4/13)

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Attempted suicide, by mail order: Abrus precatorius. (5/13)

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A recombinant mutant abrin A chain expressed in Escherichia coli can be used as an effective vaccine candidate. (6/13)

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The role of the C-terminal region of pulchellin A-chain in the interaction with membrane model systems. (7/13)

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A new triterpenoid saponin from Abrus precatorius Linn. (8/13)

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Define Abrus precatorius. Abrus precatorius synonyms, Abrus precatorius pronunciation, Abrus precatorius translation, English dictionary definition of Abrus precatorius. or n , pl -ties 1. other names for Indian liquorice 2. the seed of the Indian liquorice n., pl. -ties. 1. the Indian licorice, Abrus precatorius, of the...
Gambar 2. Buah saga. Tumbuhan ini banyak tumbuh secara liar di hutan-hutan, ladang-ladang atau sengaja dipelihara di pekarangan. Tumbuh dengan baik pada daerah dataran rendah sampai ketinggian 1000 meter di atas permukaan laut.. 6. Penelitian mekanisme antikanker. Abrin and agglutinin-I from the seeds of Abrus precatorius are type II ribosome-inactivating proteins that inhibit protein synthesis in eukaryotic cells. The two toxins share a high degree of sequence similarity; however, agglutinin-I is weaker in its activity (Bagaria et al., 2006).. Abrus agglutinin (AAG), a hetero tetrameric gal beta (1-3) NAc gal specific lectin, is isolated from seeds of Abrus precatorius. In our previous studies we found that the protein could act as an immunomodulator and immunoadjuvant in native (NA) and heat denatured (HDA) conditions. An anticancer effect of the lectin is reported, but its mode of action is not clearly known (Gosh, 2007).. Daftar Pustaka. Inventaris Tanaman Obat Indonesia, 1994. Ashima ...
The EtOH extract of Abrus schimperi (Fabaceae), collected in Kenya, demonstrated significant activity against Leishmania donovani promastigotes with IC50 value of 3.6 microg/mL. Bioassay-guided fractionation of CHCl3 fraction using Centrifugal Preparative TLC afforded two antiparasitic isoflavanquinones, namely amorphaquinone (1) and pendulone (2). They displayed IC50 values of 0.63 microg/mL and 0.43 microg/mL, respectively, against L. donovani promastigotes. Both the compounds were also evaluated against L. donovani axenic amastigotes and amastigotes in THPI macrophage cultures. In addition, compounds 1 and 2 showed antiplasmodial activity against Plasmodium falciparum D6 and W2 strains, while 2 displayed antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureus (each IC50 1.44 microg/mL). The 1H and 13C data of 1, not fully assigned previously, were unambiguously assigned using 1D and 2D NMR HMBC and HMQC experiments. In addition, the absolute stereochemistry of ...
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Botanical Name : Abrus precatorius Family: Fabaceae Genus: Abrus Species: A. precatorius Kingdom: Plantae Order: Fabales Synonyms : Abrus minor and A.
Padhi, P (2014) Terminalia bellerica (baheda) inhibits protective autophagy and induces apoptosis in oral cancer cell lines. MSc thesis.. Panda, Madhusmita (2014) Concanavalin A induced autophagy switches to apoptosis. MSc thesis.. Panda, Prashanta Kumar (2017) Autophagy Dependent Cell Death, Senescence and Differentiation by Abrus Agglutinin in Cancer Therapeutics. PhD thesis.. Panda , Himadri Tanaya (2013) Elucidation of the anticancer property of Abrus agglutinin in oral cancer cell lines. MSc thesis.. Patel, Priti (2015) Synergistic Effect of Trichostatin a and Thymoquinone in Inducing Anticancer Activity in Breast Cancer. MSc thesis.. Pradhan, Naina (2011) DNA Methylation and Cancer. MSc thesis.. Pradhan, Sonali (2014) Deciphering the anti-cancer efficacy of azadirachta indica and its role in re-expression of e-cadherin in breast cancer via snail and hdacs. MSc thesis.. Prasad, Sneha (2012) Isolation and characterization of lectins from red seeds of Abrus precatorius. MSc ...
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Abrin is a highly toxic toxalbumin found in the seeds of the rosary pea (or jequirity pea), Abrus precatorius. It has a median toxic dose of 0.7 micrograms per kilogram of body mass when given to mice intravenously (approximately 31.4 times more toxic than ricin, being 22 micrograms per kilogram). The median toxic dose for humans ranges from 10 to 1000 micrograms per kilogram when ingested and is 3.3 micrograms per kilogram when inhaled. Abrin is a ribosome inhibiting protein like ricin, a toxin which can be found in the seeds of the castor oil plant. It is classed as a "Select Agent" under U.S. law. Abrin is a water-soluble lectin. Abrin in powdered form is yellowish-white. It is a stable substance and can withstand extreme environmental conditions. Though it is combustible, it does not polymerize easily and is not particularly volatile. Abrin is not known to have been weaponised. Abrin naturally occurs in the seeds of the rosary pea, a plant common to tropical regions that is occasionally ...
Hegde, Ramesh and Podder, Sunil K (1998) Evolution of tetrameric lectin Ricinus communis agglutinin from two variant groups of ricin toxin dimers. In: European Journal of Biochemistry, 254 (03). pp. 596-601. Hegde, Ramesh and Podder, Sunil K (1997) A- and B-Subunit Variant Distribution in the Holoprotein Variants of Protein Toxin Abrin: Variants of Abrins I and III Have Constant Toxic A Subunits and Variant Lectin B Subunits. In: Archives of Biochemistry and Biophysics, 344 (1). pp. 75-84. Hegde, Ramesh (1992) Coated pits,endosome CURLing and intracellular receptor--ligand trafficking. In: Current Science (Bangalore), 62 (8). pp. 555-564. Hegde, Ramesh and Podder, Sunil K (1991) Studies on the variants of the protein toxins ricin and abrin. In: European Journal of Biochemistry, 204 (1). pp. 155-164. Hegde, Ramesh and Podder, SK and Maitia, TK (1991) Purification and characterization of three toxins and two agglutinins from Abrus precatorius seed by using lactamyl-Sepharose affinity ...
(20S,22S)-3beta,22-dihydroxycucurbita-5(10),24-diene-26,29-dioic acid delta-lactone: triterpenoid from the leaves of Abrus precatorius (Leguminosae); structure in first source
EFFECTS OF SHORT-TERM (LESS THAN 8-HOURS) EXPOSURE: Abrin poisons the cells of the body by blocking (inhibiting) the formation (synthesis) of essential components of cells (proteins). Contact of abrin with the skin, eyes, lungs, or the moist lining of body passages and cavities (mucous membranes) can cause severe irritation, inflammation, and internal bleeding (hemorrhage). The health effects caused by abrin depend on the route of exposure and the amount of abrin to which the patient/victim is exposed. Ingestion of abrin produces severe vomiting (emesis) and diarrhea that may result in serious dehydration (hypovolemic shock) and multi-system organ failure affecting the gastrointestinal (GI) tract, kidneys, liver and pancreas; these effects are potentially fatal. In addition to cough and fever, inhalation of abrin may cause fluid accumulation in the lungs (pulmonary edema) and respiratory distress; these effects are potentially fatal. Illness resulting from exposure to abrin cannot be transmitted ...
EFFECTS OF SHORT-TERM (LESS THAN 8-HOURS) EXPOSURE: Abrin poisons the cells of the body by blocking (inhibiting) the formation (synthesis) of essential components of cells (proteins). Contact of abrin with the skin, eyes, lungs, or the moist lining of body passages and cavities (mucous membranes) can cause severe irritation, inflammation, and internal bleeding (hemorrhage). The health effects caused by abrin depend on the route of exposure and the amount of abrin to which the patient/victim is exposed. Ingestion of abrin produces severe vomiting (emesis) and diarrhea that may result in serious dehydration (hypovolemic shock) and multi-system organ failure affecting the gastrointestinal (GI) tract, kidneys, liver and pancreas; these effects are potentially fatal. In addition to cough and fever, inhalation of abrin may cause fluid accumulation in the lungs (pulmonary edema) and respiratory distress; these effects are potentially fatal. Illness resulting from exposure to abrin cannot be transmitted ...
Rebecca McCue has been with the Stanford School of Medicine since 2007. Before joining the Department of Medicine and SCCR, she worked in clinical research related to the fields of Pain Medicine, Neuroscience, and Psychology. She spent time in pediatric research in Philadelphia before moving to Stanford, and has a background in Biological Basis of Behavior from the University of Pennsylvania. In her current role as Associate Director with the SCCR, Rebecca focuses on infrastructure development, organizational efficiencies, community building and workforce satisfaction, and educational development. She is also a member of the Stanford Education and Planning Initiative (SEPI) and the Research Personnel Advisory Committee (RPAC). ...
Boumkaye is a traditional fermented millet-based drink (Pennisetum glaucum L.) produced in Casamance (region in Senegal). Unknown and circumcised beverage, it has therapeutic properties due to aqueous creeper extracts from Abrus pulchellus plant and naturally present during the process. The objective of this work was to investigate the fabrication process of a millet-based beverage as an alternative source of nutrients. The diagnosis of beverage production by monitoring its physical and chemical parameters during two months of storage at room temperature was studied. The established manufacturing process, composed by a production of aqueous extracts after maceration of the Abrus pulchellus vines, a preparation of millet slurry, and a fermentation step to obtain the Boumkaye, has several features. The study of aging process showed probable lactic and alcoholic fermentations. Further, the finished Boumkaye was characterized by a high acidity (pH of 3), an alcohol content of 5 g/100g and contains an
Toxalbumins are toxic plant proteins that disable ribosomes and thereby inhibit protein synthesis, producing severe cytotoxic effects in multiple organ systems. They are dimers held together by a disulfide bond and comprise a lectin (carbohydrate-binding protein) part which binds to the cell membrane and enables the toxin part to gain access to the cell contents. Toxalbumins are similar in structure to the toxins found in cholera, tetanus, diphtheria and botulinum; and their physiological and toxic properties are similar to those of viperine snake venom. Toxalbumins were first described in about 1890 by Ludwig Brieger (1849-1919) and Sigmund Fraenkel (1868-1939), associates of the organic chemist Eugen Baumann. Brieger first used the term toxin. Toxalbumins notably are present in the plant families Leguminosae and Euphorbiaceae, occurring for instance in Robinia pseudoacacia, Abrus precatorius, Jatropha curcas, Croton gratissimus and Ricinus communis. Typical toxalbumins are abrin and ricin. ...
At one end of the testa, there is a scar, called hilum. The hilum is the position of attachment of seed with its stalk, the funiculus. Near the hilum a small opening is present, called micropyle, through which water enters the seed. Sometimes a ridge is present beyond the hilum, opposite the micropyle, it is called raphe. It represents the base of the funiculus which becomes fused with integument. (The testa are of various natures: It may be tough and leathery in gram (Cicer arietinum) and pea (Pisum sativum) of Fabaceae; hard and horny in castor (Ricinus communis) of Euphorbiaceae; soft and fleshy in gourd (Cucurbita maxima) of Cucurbitaceae. The colour of the testa is gene-rally brown, but it may also be black in Indian shot (Canna indica) of Cannaceae; red in carbs eye (Abrus precatorius) of Fabaceae; whitish or yellow in pea (Pisum sativum) of Fabaceae etc. They also vary in appearance, such as smooth in pea, stria-ted in tobacco (Nicotiana tabacum) of Solanaceae; wrinkled in cumin seed ...
Angra - Acid Rain Lyrics. Miserebus Sanctus, Precatorius Ominmus Miserebus Sanctus, Precatorius Ominmus Miserebus Sanctus, Domine Deo Sabaoth! When the world had
Dr. Jean Lee studies the pathogenesis of infections caused by Staphylococcus aureus. A major focus of her laboratory has been the preclinical evaluation of S. aureus vaccine candidates in rodent models of staphylococcal disease. Her primary effort is directed toward the design and evaluation of a multicomponent S. aureus bioconjugate vaccine expressed in Escherichia coli by glyco-engineering technology. In addition, she has active collaborations (and funding) with laboratories in Chicago and Maryland for the development of other multicomponent S. aureus vaccine candidates. The Lee laboratory has developed and used animal models of S. aureus colonization and infection to study microbial interactions with the naïve host. In a rodent model of nasal carriage, bacterial factors that promote colonization have been identified, and one of these proteins (clumping factor B) was demonstrated to serve as an effective vaccine candidate to reduce colonization. The gastrointestinal tract is an important ...
Definition: a plant that produces wood as its structural tissue. Wood is a structural cellular adaptation that allows woody plants to grow from above ground stems year after year, thus making some woody plants the largest and tallest terrestrial plants. Wood is usually primarily composed of xylem cells with cell walls made of cellulose and ...
https://www.chemistryworld.com/podcasts/curare-and-ouabain/3008865.article Podcasts By Jamie Durrani6 April 2018 Jamie Durrani presents a pair of plant-based poisons Ben Valsler Weve got a killer double-bill this week, as Jamie Durrani presents a pair of poisons… Jamie Durrani While the hot black stuff is simmering down to about the volume of a pint, it must not be allowed to scorch. Guarding your hand with a thick green leaf, you anxiously remove individual embers from the fire or, if you think best, shove them closer to the pot and blow gently on them. It is your only means of temperature control in the most delicate and nerve-racking procedure in all the jungle. Illustration of Acokanthera schimperi flowers, leaves, fruit and seeds Source: Franz Eugen Köhler, Köhlers Medizinal-Pflanzen Acokanthera schimperi This is how the early 20th century explorer Richard Gill described how inhabitants of the Amazon rainforest produced the flying death - curare. This alkaloid is extracted from ...
o Osteoglossomorpha Greenwood, Rosen, Weitzman & Myers, 1966 (bony-tongue fishes and relatives; luukieliset) ,?- †Jiaohichthys pulchellus Ma, 1983 [Jiaohichthyidae] ,?- †Liaoxiichthys longicephalus Su, 1992 ,?- †Nierrkunia liae Su, 1992 ,?- †Suziichthys xinbinensis Su, 1992 ,?- †Ichthyodectiformes Bardeck & Sprinkle, 1969 ,?-o †Juiquanichthyidae Ma, 1984 , ,-- †Juiquanichthys liui Ma, 1984 , ,-- †Changma shenjiawanensis Ma, 1984 , `--o †Qilianichthys Ma, 1984 , ,-- †Q. hanxiaensis Ma, 1984 , `-- †Q. changmaensis Ma, 1984 ,-- †Lycopteridae Liu, Su, Huang & Chang, 1963 [Lycopteriformes] `--+?-o †Kuyangichthidae Liu, Ma & Liu, 1982 , ,-- †Kuyangichthys microdus Liu, Ma & Liu, 1982 , `-- †Pulinia baojiatunensis Ma, 1983 ,-- Hiodontiformes Taverne, 1979 (kuusilmäkalat) `--+--o †Paralycoptera Chang & Chou, 1977; U. Jur. EAs. , ,-- †P. wui Chang & Chou, 1977 , `-- †P. changi Ma & Sun, 1988 `--+-- †Jinanichthys longicephalus Ma & Sun, 1988 `--o Osteoglossiformes ...
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The aim of this study is to evaluate the antioxidant activity, α-amylase inhibition activity, estimation of total phenolic and flavonoid content and the toxicity in ten medicinal plants Woodfordia fructicosa, Tectaria coadunate, Prunus cerasoides, Abrus precatorius, Eclipta prostrate, Poranopsis paniculata, Chenopodium album, Oroxylum indicum, Curcuma caesia, and Butea monosperma collected from Gorkha District of Nepal. Methanolic extracts of all the plants showed the presence of different phytoconstituents such as alkaloids, polyphenols, flavonoids, terpenoids, saponins, glycosides, and quinones. The highest radical scavenging was observed in methanol extract of P. cerasoides with IC50 = 7.54±0.223 µg/ml. The potency of the radical scavenging effect of P. cerasoides was about six times greater than standard ascorbic acid (39.85±0.025 µg/ml) taken. P. cerasoides showed high phenol content (805.48±0.024 mg GAE/g extract) whereas total flavonoid content varied
The African crested rat is a thief, but its loot only becomes obvious if you take a bite out of it. Doing so would give you a mouthful of ouabain, a poison so strong that it can kill an elephant. The rat doesnt make the poison itself. Instead, it pilfers it from the local Acokanthera schimperi tree. It gnaws on the roots and bark, chews them up, and slavers a coarse toxic gel onto the special hairs on its flanks. Local people use the same poison to coat their arrowheads. The rat uses it as a chemical shield.. The crested rat is found throughout eastern Africa. It is normally sluggish but when threatened, it puts on a vivid display. It pulls its head back, turns sideways onto its attacker and parts the grey fur on its flanks using special muscles. These actions draw attention to a leaf-shaped crest of brown hairs on its side, which are encircled by a "target" of black and white. Its almost as if the rat is daring a predator to bite it.. Any animal that takes up the invitation is in for trouble. ...
Araneae - Spiders of Europe. An identification tool to European spiders with species descriptions, scientific drawings, distributions and other species related informations
be, Giovan Cosimo Bonomo, 1687. Christian Gottfried Ehrenberg( DE) catalogued the filtration besser as a likely polio for some uncertain patients. Konishi( JP) gave a photo of description, independently acquired adults( AucklandNew mercury), changed by Psychiatric ordinary Thousands approximately experiencing their sites( 3299).
Species: P. albifacies - P. calopterus - P. capitalis - P. fumifrons - P. latirostris - P. luluae - P. plumbeiceps - P. pulchellus - P. ruficeps - P. russatus - P. senex - P. sylvia. Name. Poecilotriccus Berlepsch, 1884. Reference. Journal für Ornithologie 32 p.298. ...
Build: Wed Jun 21 18:33:50 EDT 2017 (commit: 4a3b2dc). National Center for Advancing Translational Sciences (NCATS), 6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-435-0888. ...
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Abildgaardia ovata (Burm.f.) Kral Abrus canescens Welw. ex Baker Abrus melanospermus Hassk. Abrus precatorius L. Abutilon ...
Abrus precatorius L. Aeschynomene brasiliana (Poir.) DC. Aeschynomene evenia Whigh. Aeschynomene falcata (Poir.) DC. ...
"Abrus Lele Biography and Olympic Results". sport-reference.com. Retrieved 2010-01-24. ...
"Abrus Precatorius - Medicinal Uses, Benefits of Abrus". Planetayurveda.com. Retrieved 2015-06-16. Rietschel, Ernst T.; Westphal ... Abrus precatorius, Jatropha curcas, Croton gratissimus and Ricinus communis. Typical toxalbumins are abrin and ricin. Ingestion ...
Seeds of Abrus precatorius are traditionally used. Each player controls one of the rows. At her turn, the player takes all the ...
Hymenocardiaceae) Abrus precatorius Cissus populnea Flabellaria paniculata Cav., Morinda lucida, Parkia biglobosa (Jacq) Benth ...
... abrus (wd , gwp gwe g , in it p) MeSH B06.388.100.401.025 --- acacia (wd , gwp gwe g , in it p) MeSH B06.388.100.401.051 --- ...
Adults were reared from larvae found feeding on Abrus precatorius. funet.fi Exotic Microlep. 4: 348 Archived 2015-09-23 at the ...
... is a Rajasthani language word for Abrus precatorius / Jequirity. A married girl is climbing on chirmi plant waits for ...
isolated from tropical legumes, Sesbania rostrata and Abrus precatorius, respectively". Symbiosis. 34 (1): 53-68. Because no ...
Some of the plant species recorded here include: Abrus precatorius L. liana Abutilon indicum (L) Sweet. shrub Acacia ...
Abrus precatorius, Ormosia coccinea and Ormosia minor); also meaning something very beautiful, punqu door, pünqu (ü stand for a ...
They resemble the seeds of Abrus, snoutbeans (Rhynchosia), and Adenanthera, but are much larger than the former two. In ...
... (possibly from Aymara wayruru red and black seeds of a plant (Abrus precatorius, Ormosia coccinea and Ormosia minor ...
... is a highly toxic toxalbumin found in the seeds of the rosary pea (or jequirity pea), Abrus precatorius. It has a median ...
The larvae feed on the flowers and seedpods of various woody legumes, including Cassia brachiata, Abrus precatorius and ...
The temple gets its name from the Gunja tree (Abrus precatorious) that grows in the front of the main entrance. Sculptures in ...
Eggs are laid on Abrus precatorius, Falcataria moluccana, Acacia species, Aeschynomene species and numerous other Leguminosae, ...
The larva has been recorded as feeding on Pongamia glabra, Derris scandens, Abrus precatorius (Leguminosae), Xylia ...
He has worked on the toxicity of Abrus precatorius on the maternal and fetal tissues, Kyasanur forest disease and South Indian ...
This mythology has made the Gunjā (Abrus precatorius) seeds - the bright red seed of a fig tree - also a favourite for native ...
Invasive plant species that threaten the habitat include Brazilian pepper (Schinus terebinthifolius), rosary pea (Abrus ...
... (possibly from Quechua yuraq white, wayruru a type of tree, Aymara wayruru red and black seeds of a plant (Abrus ...
The new species included Abrus, Abelmoschus, Lablab, and Melochia, each of which are native to tropical areas and were ...
They include Abrus precatorius, Aloe vera, Annona squamosa, Bryonia lacinosa, Aegle marmelos, Madhuca indica, Ficus racemosa, ...
Abrus precatorius synonyms, Abrus precatorius pronunciation, Abrus precatorius translation, English dictionary definition of ... Abrus precatorius. or n , pl -ties 1. other names for Indian liquorice 2. the seed of the Indian liquorice n., pl. -ties. 1. ... It has been reported that Abrus abrin, isolated from the seeds of Abrus precatorius, showed in vitro and in vivo antitumor ... Abrus precatorius - definition of Abrus precatorius by The Free Dictionary https://www.thefreedictionary.com/Abrus+precatorius ...
Abrus aureus (Madagascar) Abrus baladensis (Somalia) Abrus bottae (Saudi Arabia, Yemen) Abrus canescens (Africa) Abrus ... Abrus pulchellus (Africa) Abrus sambiranensis (Madagascar) Abrus schimperi (Africa) Abrus somalensis (Somalia) Abrus wittei ( ... Abrus fruticulosus (India) Abrus gawenensis (Somalia) Abrus laevigatus (Southern Africa) Abrus longibracteatus (Laos, Vietnam) ... Abrus madagascariensis (Madagascar) Abrus parvifolius (Madagascar) Abrus precatorius L. - Jequirity (Africa, Australia, ...
click on a thumbnail to view an image, or see all the Abrus thumbnails at the Plants Gallery ...
Abrus precatorius leaves and flowers Abrus precatorius flowers Abrus precatorius seeds List of plants of Caatinga vegetation of ... 5. "Saga, Abrus precatorius Linn". StuartXchange. "Abrus precatorius subsp. africanus". www.plantzafrica.com. Retrieved 2016-05 ... Abrus precatorius L. Abrus precatorius Linn. Medicinal Plant Images Database (School of Chinese Medicine, Hong Kong Baptist ... Antibacterial and antifungal activity of methanolic extract of Abrus pulchellus Wall and Abrus precatorius Linn: A comparative ...
GlucoseGlucose: In streptozotocin-induced diabetic Wistar rats, administration of the aqueous extract of Abrus precatorius ( ... CholesterolCholesterol: In streptozotocin-induced diabetic Wistar rats, administration of the aqueous extract of Abrus ...
The best binders were specific for the Abrus agglutinin, showing minimal binding to purified abrin fractions or unrelated ... Abrus agglutinin (a protein related to abrin but with lower toxicity), ricin, and unrelated proteins. Isolated sdAb were also ... we determined that the commercial toxoid preparation used for the original immunizations contained a high percentage of Abrus ... Abrus agglutinin and distinguish between different crude preparations. ...
Abrus precatorius. L.. Abrus precatorius, known commonly as Jequirity, Crabs Eye, Rosary Pea, John Crow Bead, Precatory bean ... The toxin present in Abrus precatorius is a close relative to ricin called abrin. It is a dimer consisting of two protein ... The Tamils use Abrus precatorius seeds of different colors. The red variety with black eye is the most common, but there are ... The seeds of Abrus precatorius are much valued in native jewelry for their bright coloration. The third of the bean with the ...
The present study focuses on isolation and evaluation of the anti-cancer activity of compounds from the leaves of Abrus ... Bhardwaj DK, Bisht MS, Mehta CK (1980) Flavonoids from Abrus precatorius. Phytochemistry 19:2040-2041CrossRefGoogle Scholar ... Ghosal S, Dutta SK (1971) Alkaloids of Abrus precatorius. Phytochemistry 10:195-198CrossRefGoogle Scholar ... The present study focuses on isolation and evaluation of the anti-cancer activity of compounds from the leaves of Abrus ...
View Name Sources Download CSV Download BibTeX Bibliography for Abrus+repens by Page ...
Abrus precatorius L.. 1.2 Family Leguminosae. 1.3 Common name(s) Abrus seed. Aivoeiro. Arraccu-mitim. Buddhist rosary bead. ... They are abrus agglutinin (a haemagglutinin) and the toxic principles abrins [a] to [d].. Abrus agglutinin is a tetramer with a ... Abrus precatorius mature or immature seeds are chewed or ingested.. 5.2 Inhalation Unknown.. 5.3 Dermal Unknown.. 5.4 Eye Cold ... Abrus precatorius is a wild plant that grows best in fairly dry regions at low elevations.. 3.1.3 Distribution It grows in ...
Abrus precatorius (Rosary Pea) is also commonly known as Gunja. Here we are explaining its Uses, Benefits, Dosage and ... Rosary Pea (Abrus precatorius). Better known as Rosary pea, Crabs eye and popularly known as Gunja in Hindi, Abrus precatorius ... Abrus precatorius is a very strong herb and when given in a little bit of overdose, it may lead to severe vomiting and ... Recent Research on Abrus Precatorius. Ethanolic seed extracts of Gunja can help in delay the progression of cataract. ...
Key words: Abrus precatorius, Sephadex, Drangendoffs reagent, paracetamol. ... The therapeutic effect of an alkaloid-rich fraction of the chloroform-methanol extract of Abrus precatorius seeds on ... The therapeutic effect of an alkaloid-rich fraction of the chloroform-methanol extract of Abrus precatorius seeds on ... Therapeutic effect of an alkaloid-rich fraction of Abrus precatorius seed methanol extract on paracetamol-induced liver damage ...
Abrus precatorius L. - Determined By: O. K. Lakela, 1966. Determination History:. Abrus precatorius L. - Determined By: O. K. ...
Abrus precatorius L. - Determined By: D. Tabb, May-1974. Locality:. USA. Florida. Miami-Dade Co.: Near Pinelands Episcopal ...
Stock Images of Abrus precatorius; Rosary Pea; Jequirty; Crabs eye; Precatory bean; Mutual Love Bean; Xiang-si-dou;; Steven ... Abrus precatorius; Rosary Pea; Jequirty; Crabs eye; Precatory bean; Mutual Love Bean; Xiang-si-dou; ...
Song C, Hu Z (1998) Abruquinone A, B, D, E, F, and G from the root of Abrus precatorius. Acta Bot Sin 40:734-739Google Scholar ... Abrus precatorius Antifungal Isoflavanquinones Leishmania Neglected tropical diseases This is a preview of subscription content ... Bhardwaj D, Bisht M, Mehta C (1980) Flavonoids from Abrus precatorius. Phytochemistry 19:2040-2041CrossRefGoogle Scholar ... Xiao Z, Wang F, Sun A, Li C, Huang C, Zhang S (2012) A new triterpenoid saponin from Abrus precatorius Linn. Molecules 17:295- ...
One step Purification and Characterisation of Abrin Toxin from Abrus Precatorius Seeds * Swati Banger DRDO-Defence Research and ... In the present work, we have extracted and purified the abrin toxin from Abrus precatorius seeds. The toxin was purified using ... Abrin is a plant toxin obtained from Abrus precatorius seeds. It belongs to the type II ribosomal inactivating proteins (RIPs) ... One step Purification and Characterisation of Abrin Toxin from Abrus Precatorius Seeds. Defence Life Science Journal, 4(4), 231 ...
Anticancer Activity Of Petroleum Ether Extract Of Abrus Precatorius On Ehrlich Ascitis Carcinoma In Mice. ...
... ,Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India has indicated the use of ...
abrus_precatorius compound_leaves creeping_herb extensive_creeper Fabaceae Gunja Jequirity kuch Lalkuch Mahabharata Rokta ... Roti, Kuch or Jequirity (Abrus precatorius, family: Fabaceae) is a deciduous creeping woody herb. It grows naturally on fallow ...
This appears to be the first report of amorphaquinone (1) and pendulone (2) from the genus Abrus. ... The EtOH extract of Abrus schimperi (Fabaceae), collected in Kenya, demonstrated significant activity against Leishmania ...
Saga/Red Lucky Seed (Abrus precatorius Linn). Saga. /Red Lucky Seed (Abrus precatorius Linn) ... Abrus agglutinin (AAG), a hetero tetrameric gal beta (1-3) NAc gal specific lectin, is isolated from seeds of Abrus precatorius ... Abrus agglutinin (AAG), a hetero tetrameric gal beta (1-3) NAc gal specific lectin, is isolated from seeds of Abrus precatorius ... Abrin and agglutinin-I from the seeds of Abrus precatorius are type II ribosome-inactivating proteins that inhibit protein ...
Abrus precatorius, popularly known as kuch or rati&rsq.. ... Abrus precatorius, popularly known as kuch or rati, is used ... Abrus precatorius poisoning leading to hemorrhagic gastroduodenitis- a rare experience ... Abrus precatorius poisoning leading to hemorrhagic gastroduodenitis� a rare experience. Dibbendhu Khanra1*, Arunansu Talukdar1 ... Keywords: Abrus precatorius; kuch; Hemorrhagic gastroduodenitis; Supportive therapy. Subscription required. Please login to ...
A new pterocarpan from the leaves of Abrus precatorius L.. Citation:. Malele CN, Langat-Thoruwa CC, Guantai AN, Chhabra SC. "A ... compound 1) was isolated from the dichloromethane extract of the leaves of Abrus precatorius L. The. structure of the compound ... new pterocarpan from the leaves of Abrus precatorius L." Academic journals. 2015;9(27):749-754,.. Abstract:. A pterocarpan, 2,3 ...
Buy Abrus Precatorius Plant online at low price in India. Huge collection of plants and seeds only at Plants Guru. ✔ Free ... Abrus Precatorius Plant - Coral Bead Vine, Rosary Pea, Gunj. 0 reviews / Write a review ... Abrus Precatorius Plant - Coral Bead Vine, Rosary Pea, Gunj. Common Name(s):. Rosary Pea, Crabs Eyes, Jequirity. Category:. ... Abrus Precatorius Plant - Coral Bead Vine, Rosary Pea, Gunj. ... Product Code: pg-medicinal-plants-abrus-prectarios. * ...
  • This appears to be the first report of antileishmanial activity of compounds 1 and 2 from the genus Abrus against cutaneous leishmaniasis and validates the use of A. precatorius in treating dermatology diseases. (springer.com)
  • This appears to be the first report of amorphaquinone (1) and pendulone (2) from the genus Abrus. (ac.ke)
  • Abrus aureus (Madagascar) Abrus baladensis (Somalia) Abrus bottae (Saudi Arabia, Yemen) Abrus canescens (Africa) Abrus cantoniensis Hance (China) Abrus diversifoliatus (Madagascar) Abrus fruticulosus (India) Abrus gawenensis (Somalia) Abrus laevigatus (Southern Africa) Abrus longibracteatus (Laos, Vietnam) Abrus madagascariensis (Madagascar) Abrus parvifolius (Madagascar) Abrus precatorius L. - Jequirity (Africa, Australia, Southeast Asia) Abrus pulchellus (Africa) Abrus sambiranensis (Madagascar) Abrus schimperi (Africa) Abrus somalensis (Somalia) Abrus wittei (Zaire) Hartley, Martin R. (2010). (wikipedia.org)
  • Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi. (ac.ke)
  • citation needed] According to the 1898 King's American Dispensatory, Abrus seeds are the agents by which the Chamàr or "Native Skinner" caste of India carry on the felonious poisoning of cattle for the purpose of securing their hides. (wikipedia.org)
  • Abrus precatorius is a vine native to India and other tropical and subtropical areas of the world. (westjem.com)
  • Once Abrus precatorius plants have grown to maturity under favourable conditions, their deep roots are extremely difficult to remove, and the plants' aggressive growth, hard-shelled seeds, and ability to sucker, renders an infestation extremely difficult to eradicate and makes it very difficult to prevent re-infestation. (wikipedia.org)
  • H(100), leaves, roots of Abrus. (africamuseum.be)
  • We present a case of a man who survived an intentional ingestion of crushed Abrus seeds after he was treated with aggressive gastric decontamination and supportive care. (westjem.com)