Abortion, Habitual: Three or more consecutive spontaneous abortions.Heparin, Low-Molecular-Weight: Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.Thrombophilia: A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.Antibodies, Antiphospholipid: Autoantibodies directed against phospholipids. These antibodies are characteristically found in patients with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; related autoimmune diseases, some non-autoimmune diseases, and also in healthy individuals.Antiphospholipid Syndrome: The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).Anticoagulants: Agents that prevent clotting.Abortion, Induced: Intentional removal of a fetus from the uterus by any of a number of techniques. (POPLINE, 1978)Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)Enoxaparin: Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)Nadroparin: A heparin fraction with a mean molecular weight of 4500 daltons. It is isolated from porcine mucosal heparin and used as an antithrombotic agent. (From Merck Index, 11th ed)Poly A: A group of adenine ribonucleotides in which the phosphate residues of each adenine ribonucleotide act as bridges in forming diester linkages between the ribose moieties.Editorial Policies: The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Fagopyrum: A plant genus of the family POLYGONACEAE that is used as an EDIBLE GRAIN. Although the seeds are used as cereal, the plant is not one of the cereal grasses (POACEAE).Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Medical Staff: Professional medical personnel who provide care to patients in an organized facility, institution or agency.Life Tables: Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.Job Application: Process of applying for employment. It includes written application for employment or personal appearance.Turner Syndrome: A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.Amniocentesis: Percutaneous transabdominal puncture of the uterus during pregnancy to obtain amniotic fluid. It is commonly used for fetal karyotype determination in order to diagnose abnormal fetal conditions.Chorionic Villi Sampling: A method for diagnosis of fetal diseases by sampling the cells of the placental chorionic villi for DNA analysis, presence of bacteria, concentration of metabolites, etc. The advantage over amniocentesis is that the procedure can be carried out in the first trimester.Abortion, Legal: Termination of pregnancy under conditions allowed under local laws. (POPLINE Thesaurus, 1991)Chorion: The outermost extra-embryonic membrane surrounding the developing embryo. In REPTILES and BIRDS, it adheres to the shell and allows exchange of gases between the egg and its environment. In MAMMALS, the chorion evolves into the fetal contribution of the PLACENTA.Abortion, Spontaneous: Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.New YorkPrenatal Diagnosis: Determination of the nature of a pathological condition or disease in the postimplantation EMBRYO; FETUS; or pregnant female before birth.Materia Medica: Materials or substances used in the composition of traditional medical remedies. The use of this term in MeSH was formerly restricted to historical articles or those concerned with traditional medicine, but it can also refer to homeopathic remedies. Nosodes are specific types of homeopathic remedies prepared from causal agents or disease products.Metrorrhagia: Abnormal uterine bleeding that is not related to MENSTRUATION, usually in females without regular MENSTRUAL CYCLE. The irregular and unpredictable bleeding usually comes from a dysfunctional ENDOMETRIUM.Menorrhagia: Excessive uterine bleeding during MENSTRUATION.Food Coloring Agents: Natural or synthetic dyes used as coloring agents in processed foods.Medicine, Chinese Traditional: A system of traditional medicine which is based on the beliefs and practices of the Chinese culture.Dictionaries, MedicalGeranium: A plant genus of the family GERANIACEAE. Geranium is also used as a common name for PELARGONIUM.Dictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Urtica dioica: A plant species of the genus Urtica, family URTICACEAE. Roots have been used to treat PROSTATIC HYPERPLASIA. Leaves are edible after the stinging quality is eliminated by brief heating.Veratrum Alkaloids: Alkaloids with powerful hypotensive effects isolated from American or European Hellebore (Veratrum viride Ait. Liliaceae and Veratrum album L. Liliaceae). They increase cholinergic and decrease adrenergic tone with appropriate side effects and at higher doses depress respiration and produce cardiac arrhythmias; only the ester alkaloids have been used as hypotensive agents in specific instances. They have been generally replaced by drugs with fewer adverse effects.Viburnum: A plant genus in the family CAPRIFOLIACEAE. The common name derives from its traditional use for menstrual cramps. It is a source of viburnine, valerianic acid, vibsanin, and ursolic acid. Note that true cranberry is VACCINIUM MACROCARPON.Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Uterine Inertia: Failure of the UTERUS to contract with normal strength, duration, and intervals during childbirth (LABOR, OBSTETRIC). It is also called uterine atony.Flatulence: Production or presence of gas in the gastrointestinal tract which may be expelled through the anus.Colic: A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.Killer Factors, Yeast: Protein factors released from one species of YEAST that are selectively toxic to another species of yeast.Hypocreales: An order of fungi in the phylum ASCOMYCOTA that includes a number of species which are parasitic on higher plants, insects, or fungi. Other species are saprotrophic.
(1/515) Ganglioside GM2-activator protein and vesicular transport in collecting duct intercalated cells.

This study describes the molecular characterization of an antigen defined by an autoantibody from a woman with habitual abortion as GM2-activator protein. The patient showed no disorder of renal function. Accidentally with routine serum screening for autoantibodies, an immunoreactivity was found in kidney collecting duct intercalated cells. Three distinct patterns of immunostaining of intercalated cells were observed: staining of the apical pole, basolateral pole, and diffuse cytoplasmic labeling. Ultrastructurally, the immunoreactivity was associated with "studs," which represent the cytoplasmic domain of the vacuolar proton pump in intercalated cells. This pump is subjected to a shuttling mechanism from cytoplasmic stores to the cell membrane, which exclusively occurs in intercalated cells. Peptide sequences of a 23-kD protein purified from rat kidney cortex showed complete identity with corresponding sequences of GM2-activator protein. In the brain, GM2-activator protein is required for hexosaminidase A to split a sugar from ganglioside GM2. Because neither ganglioside GM2 nor GM1 (its precursor) is present in significant amounts in the kidney, the previous finding that this tissue contains the highest level of activator protein in the body was confusing. In this study, a novel role for GM2-activator protein in intercalated cells is proposed, and possible roles in the shuttling mechanism are discussed.  (+info)

(2/515) Factor V Leiden and antibodies against phospholipids and protein S in a young woman with recurrent thromboses and abortion.

We describe the case of a 39-year-old woman who suffered two iliofemoral venous thromboses, a cerebral ischemic infarct and recurrent fetal loss. Initial studies showed high levels of antiphospholipid antibodies (APAs) and a moderate thrombocytopenia. After her second miscarriage, laboratory diagnosis revealed that the woman was heterozygous for the factor V Leiden mutation and had a functional protein S deficiency as well as anti-protein S and anti-beta 2-glycoprotein I antibodies. The impairment of the protein C pathway at various points could well explain the recurrent thromboses in the patient and supports the role of a disturbed protein C system in the pathophysiology of thrombosis in patients with APAs.  (+info)

(3/515) Possible mechanisms of immunotherapy for maintaining pregnancy in recurrent spontaneous aborters: analysis of anti-idiotypic antibodies directed against autologous T-cell receptors.

We examined whether immunotherapy for recurrent spontaneous abortion (RSA) using paternal lymphocytes induces anti-T-cell receptor (TCR) idiotypic antibodies in RSA patients. The sera of these patients were assessed for inhibitory activity against mixed lymphocyte reactions (MLR) between maternal responder cells and paternal stimulator cells. Sera of four of the five women who maintained pregnancy successfully after immunotherapy showed significant MLR inhibition, whereas none of the five women who had unsuccessful pregnancies showed significant MLR inhibition. These sera inhibited the MLR of autologous responder T-cells, when stimulated with lymphocytes having the same HLA-DR antigens as the patient's husband, but not when stimulated with lymphocytes having unrelated HLA-DR antigens. This MLR inhibitory activity was absorbed by autologous maternal T-lymphoblasts induced by stimulation with lymphocytes having the paternal HLA-DR type but not by those induced by stimulation with lymphocytes having other HLA-DR types. The maternal serum inhibited the proliferation of autologous T-cells, but not of non-autologous T-cells, stimulated with paternal lymphocytes. These results indicate that anti-TCR idiotypic antibodies were induced in RSA patients by immunotherapy. These antibodies may contribute to maintaining pregnancy by negatively regulating maternal T-cells directed against HLA-DR antigens of the fetus.  (+info)

(4/515) Prevention of recurrent spontaneous abortion by intravenous immunoglobulin: a double-blind placebo-controlled study.

The aim of this study was to evaluate the therapeutic efficacy of intravenous immunoglobulin (IVIG) in the prevention of recurrent spontaneous abortion (RSA). In a double-blind, randomized, placebo-controlled study, 41 women with a history of unexplained recurrent spontaneous abortion were treated with IVIG or saline infusions during pregnancy. The birth of a child was considered a successful outcome. The overall success rate was 77% in the IVIG group compared with 79% in the placebo group. For women with primary RSA the success rates were 82 (IVIG) and 89% (placebo), and for women with secondary RSA the rates were 73 (IVIG) and 70% (placebo). We found no statistically significant difference in treatment results between IVIG and placebo.  (+info)

(5/515) Neospora caninum infection and repeated abortions in humans.

To determine whether Neospora caninum, a parasite known to cause repeated abortions and stillbirths in cattle, also causes repeated abortions in humans, we retrospectively examined serum samples of 76 women with a history of abortions for evidence of N. caninum infection. No antibodies to the parasite were detected by enzyme-linked immunosorbent assay, immunofluorescence assay, or Western blot.  (+info)

(6/515) Resection of uterine septum using gynaecoradiological techniques.

This paper presents further refinements in our technique for the resection of uterine septum. Fourteen patients [infertility (n = 9) and recurrent miscarriages (n = 5)] underwent in-office resection of a uterine septum under fluoroscopic control. The main outcome measure was complete resection of uterine septum. Resections were carried out using either hysteroscopic scissors in combination with a specially designed uterine balloon catheter, or microlaparoscopy scissors in conjunction with a cervical cannula. In all patients the septum was successfully resected without any intra-operative complications. We conclude that ambulatory gynaecoradiological resection of uterine septa is a safe and simple procedure. It avoids utilization of expensive operating room time, general anaesthesia, and some complications associated with hysteroscopic resection, such as fluid retention and electrolyte imbalance.  (+info)

(7/515) Endometriosis and unexplained recurrent spontaneous abortion: pathological states resulting from aberrant modulation of natural killer cell function?

The observation that natural killer (NK) cell activity is abnormally low in endometriosis patients and abnormally high in women with otherwise unexplained recurrent spontaneous abortion represents, at present, an intriguing curiosity. There is evidence suggesting that these conditions are associated with an opposite regulation of NK cell behaviour. This review discusses these observations and potential relationships.  (+info)

(8/515) Implications of sperm chromosome abnormalities in recurrent miscarriage.

PURPOSE: Our purpose was to assess the existence of sperm chromosome abnormalities in recurrent pregnancy loss in an assisted reproduction program. METHODS: In this prospective study, 12 sperm samples from couples undergoing in vitro fertilization with two or more first-trimester spontaneous abortions were analyzed. Diploidy and disomy in decondensed sperm nuclei were assessed for chromosomes 13, 18, 21, X, and Y using two- and three-color fluorescence in situ hybridization. RESULTS: Sex chromosome disomy in sperm samples from recurrent abortion couples was significantly increased compared to that from internal controls (0.84% vs 0.37%). In a subpopulation of seven couples who underwent oocyte donation, mean frequencies for sex chromosome disomy (1%) were even higher and diploidy (0.43%) was also significantly increased. CONCLUSIONS: These results suggest an implication of sperm chromosome abnormalities in some cases of recurrent pregnancy loss.  (+info)

*  Recurrent miscarriage
... , habitual abortion, or recurrent pregnancy loss (RPL) is three or more consecutive pregnancy losses. ...
*  3-dehydrosphinganine reductase
Assessment of five thrombophilic genetic polymorphisms among couples with habitual abortion]". Gaceta médica de México. 142 (2 ...
*  Anti-cardiolipin antibodies
... and anticardiolipin antibody in women with idiopathic habitual abortion. A controlled, prospective study of forty-four women". ... idiopathic spontaneous abortion, and systemic lupus erythematosus (SLE). They are a form of anti-mitochondrial antibody. In SLE ...
*  GroES
Gerhard I, Katzer E, Runnebaum B (1991). "The early pregnancy factor (EPF) in pregnancies of women with habitual abortions". ... Mesrogli M, Maas DH, Schneider J (1988). "[Early abortion rate in sterility patients: early pregnancy factor as a parameter]". ... "A study of early pregnancy factor activity in the sera of patients with unexplained spontaneous abortion". American Journal of ... "Early pregnancy factor as a marker for assessing embryonic viability in threatened and missed abortions". Gynecologic and ...
*  F13B
These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. F13B has been shown ...
*  Hydroxyprogesterone acetate
Indications: Secondary amenorrhea, functional uterine bleeding, in- fertility, habitual abortion, dysmen-orrhea and ... habitual abortion, dysmenorrhea, and premenstrual syndrome. OHPA is a progestogen and acts as an agonist of the progesterone ...
*  Coagulation factor XIII, A1 polypeptide
These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Coagulation factor ...
*  Miscarriage
Recurrent miscarriage ("recurrent pregnancy loss" (RPL) or "habitual abortion") is the occurrence of multiple consecutive ... An induced abortion may be performed by a physician for women who do not want to continue the pregnancy. Self-induced abortion ... Before the 1980s, health professionals used the phrase "spontaneous abortion" for a miscarriage and "induced abortion" for a ... Spontaneous abortion occurs in pregnant prairie voles when their mate is removed and they are exposed to a new male, an example ...
*  Wilson's disease
... and habitual abortion. The Wilson's disease gene (ATP7B) has been mapped to chromosome 13 (13q14.3) and is expressed primarily ...
*  Helge Stormorken
Stormorken, H; Gjemdal, T; Bjøro, K (1988). "Lupus anticoagulant: a unique case with lupus anticoagulant and habitual abortion ...
*  Medroxyprogesterone acetate
... and threatened and habitual abortion. Hartmann KE, Jerome RN, Lindegren ML, Potter SA, Shields TC, Surawicz TS, Andrews JC ( ...
*  17α-Methylprogesterone
... and has been heavily used for the treatment of habitual abortion. Subsequently, a series of events led to the exploitation of ...
*  Hydroxyprogesterone caproate
... and has been heavily used for the treatment of habitual abortion. International Agency for Research on Cancer (1979). Sex ...
*  Parent-offspring conflict
... and habitual abortion in humans. Intrauterine cannibalism The kinship theory of genomic imprinting Trivers, R.L. (1974). " ... Indeed, abortion of embryos is more common in out-crossing than in self-pollinating plants (seeds in cross-pollinating plants ... In some species, the maternal parent has evolved postfertilization abortion of few seeded pods. Nevertheless, cheating by the ... because the fetus will have a lower quality cut off point for spontaneous abortion than the mother. The mother's quality cut- ...
*  List of MeSH codes (C13)
... abortion, habitual MeSH C13.703.039.089.339 --- uterine cervical incompetence MeSH C13.703.039.093 --- abortion, incomplete ... abortion, septic MeSH C13.703.039.339 --- abortion, threatened MeSH C13.703.039.422 --- abortion, veterinary MeSH C13.703. ... abortion, septic MeSH C13.703.700.680 --- pregnancy complications, parasitic MeSH C13.703.700.715 --- puerperal infection MeSH ... MeSH C13.703.039.173 --- abortion, missed MeSH C13.703.039.256 --- ...
*  Progestin-induced virilisation
... habitual abortion and threatened abortion, and add pregnancy as a contraindication to their use because of the possibility of ... were effective in treating threatened abortion or preventing habitual abortion and withdrew approval for those indications. As ... some studies suggested that progesterone could prevent threatened abortion and might prevent habitual abortion, but oral ...
*  Abortion in Sweden
When assessing whether the offence is gross special consideration shall be given to whether the act was habitual or for profit ... Act (2005:294). Abortion in Sweden was first legislated by the Abortion Act of 1938. This stated that an abortion could be ... the length of the pregnancy at the time of abortion, method of abortion, and where the abortion was performed. One of the ... The number of abortions among teenagers was 22.5 per 1,000 women in 2009, this means that the abortion rate has decreased by ...
*  Carl-Heinz Rodenberg
... and habitual offenders", to create the basis for implementing legislative and administrative measures. Since 1941, Rodenberg ... Rodenberg denied his activities in the Reich Central Office for the Combating of Homosexuality and Abortion. He stated that ... and from 1943 was scientific director of the Reich Central Office for the Combating of Homosexuality and Abortion ( ... and also took the position of scientific director of the Reich Central Office for the Combating of Homosexuality and Abortion ( ...
*  Surrogacy in New Zealand
The Court of Appeal set a test whereby the habitual residence of a child could be decided upon. Broadly, test is to look at the ... Right to Life New Zealand Inc v Abortion Supervisory Committee [2012] NZSC 68. Punter v Secretary for Justice [2004] 2 NZLR 28 ... If a child was born overseas and was brought to New Zealand a temporary visa must be granted to the child and the habitual ... If the court concludes that the child is a habitual resident of New Zealand the Adoption Act 1955 applies, however if it ...
*  Religious views on masturbation
Williams, Daniel K. (2013). "5. Sex and the Evangelicals: Gender Issues, the Sexual Revolution, and Abortion in the 1960s". In ... "habitual masturbation". He argued that "nervous disorders, even madness, could be caused by another form of bodily excess - ... Contraception and abortion from the ancient world to the Renaissance. Cambridge, Mass.: Harvard University Press. p. 4. ISBN 0- ... masturbation is basically the same as abortion. Luther argues that marital act is a way to avoid the sin of masturbation: " ...
*  Human rights in Paraguay
Domestic violence must be "habitual" to be considered criminal. Domestic-violence charges were often withdrawn owing to family ... "restrictive abortion laws," the committee asked Paraguay to "take effective action to reduce infant and maternal mortality by, ... inter alia, revising its legislation on abortion ...and ensuring that contraceptives are available to the general public, ...
*  Die Psychologie des Verbrechers
Based on his results, he concluded that a habitual criminal can be seen as a regression of the human being to his very roots as ... As an example, he indicates child's murder or abortion to be hardly provable, whereas men could easily be found guilty for sex ... Moreover, Pollitz supports Lombroso's description of the habitual female criminal, whose physical built is supposedly very ...
*  ICD-10 Chapter XV: Pregnancy, childbirth and the puerperium
Medical abortion (O05) Other abortion (O06) Unspecified abortion (O07) Failed attempted abortion (O08) Complications following ... Pregnancy care of habitual aborter (O26.3) Retained intrauterine contraceptive device in pregnancy (O26.4) Herpes gestationis ( ... O00) Ectopic pregnancy (O01) Hydatidiform mole (O02) Other abnormal products of conception (O03) Spontaneous abortion (O04) ... abortion and ectopic and molar pregnancy (O10) Pre-existing hypertension complicating pregnancy, childbirth and the puerperium ...
*  List of ICD-9 codes 630-679: complications of pregnancy, childbirth, and the puerperium
634) Spontaneous abortion (635) Legally induced abortion (636) Illegally induced abortion (637) Unspecified abortion (638) ... Habitual aborter currently pregnant (646.4) Peripheral neuritis in pregnancy (646.5) Asymptomatic bacteriuria in pregnancy ( ... Failed attempted abortion (639) Complications following abortion and ectopic and molar pregnancies (640) Hemorrhage in early ... 630) Hydatidiform mole (631) Other abnormal product of conception (632) Abortion, missed (633.1) Ectopic pregnancy, tubal, no ...
*  Biology and political orientation
... abortion, school prayer, divorce, property taxes, and the draft. Twins were asked if they agreed or disagreed or were uncertain ... the part of the brain that detects conflicts between a habitual tendency and a more appropriate response. Liberals were ...
*  Race in the United States criminal justice system
United States portal Criminal justice portal Prisons portal Legalized abortion and crime effect Race and crime Race and ... CRAWFORD, CHARLES; CHIRICOS, TED; KLECK, GARY (August 1998). "RACE, RACIAL THREAT, AND SENTENCING OF HABITUAL OFFENDERS*". ... A 1998 study found that black defendants in Florida were significantly more likely to be sentenced as habitual offenders than ...
Background: Many factors have been implicated in the pathogenesis of unexplained recurrent spontaneous abortion (URSA). The current study was conducted to determine the possible role of antioxidant status and tumor necrosis factor-α (TNF-α) in URSA.. Methods: Reduced glutathione (GSH), glutathione reductase (GSH-R), glutathione peroxidase (GSH-PX), catalase (CAT), superoxide dismutase (SOD), nitric oxide (NO), malondialdehyde (MDA) and TNF-α were assayed in women suffering unexplained first-trimester abortions. Two groups were included, the first represented by 24 women with URSA (number of abortions 3-5) and the second included 16 women with URSA (number of abortions ,5). The control group included 20 women within their first trimester of pregnancy and 20 non-pregnant healthy females within their follicular phase.. Results: We observed that the antioxidant levels measured were significantly lower in URSA groups than in the control group (p,0.05 for each comparison). Higher TNF-α, MDA and NO ...
To explore the effectiveness of intravenous immunoglobulin (IVIG) in treating patients with unexplained recurrent spontaneous abortion (URSA) and the effect of IVIG on the level of soluble human leucocyte antigen G (sHLA-G). This prospective tr
Correction: Genetic Variants in MicroRNA Machinery Genes Are Associate with Idiopathic Recurrent Pregnancy Loss Risk. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
The EVE- technology is intended for determination of intolerance or sensitivity to female sex hormones among women with hormone-related conditions and for further treatment by desensitization procedure inducing a tolerance to the hormones the women are sensitive to.. This study is designed to evaluate the safety and the ability of the EVE- Skin-Test Panel to detect sensitivity to female sex hormones in subjects with Unexplained Recurrent Pregnancy Loss (URPL) and in Control parous, healthy women.. The Skin Test Panel includes four female hormones and three control solutions.. Hormones from the Skin Test Panel are injected intradermally during the luteal phase of the subjects menstrual cycle. The skin reactions are examined by physician for erythema and wheal after 20 minutes and 48 hours and self-assessed by the patient daily for the following month.. Skin response monthly data is analyzed and compared between unexplained recurrent pregnancy loss (UPRL) and healthy groups.. Following ...
??????????? ????????? , ??????? ????????? ??????? . ?????? ????? ????????? (habitual Abortion). ???????? ????? ????????? (habitual Abortion)
OBJECTIVE: To evaluate the potential role of measuring first-trimester maternal Pentraxin-3 levels in patients with primary unexplained recurrent pregnancy loss. STUDY DESIGN: A case control study was conducted in Ain Shams University Maternity Hospi
Th17 cells and Treg cells are recently discovered lymphocyte subsets, that are different from Th1 and Th2. Th17 cells are associated with chronic inflammation through the secretion of the inflammatory cytokines IL-17A (also known as IL-17), IL-17F, IL-6, IL-21, IL-22 and TNF-α, which play a major role in the development of organ transplant rejection (11,12). Normal pregnancy is similar to an allograft. Nakashima et al found that there were lower levels of Th17 cells in the peripheral blood of normal pregnant women (13). Recent studies reported that the proportions and concentrations of Th17 cells in the peripheral blood were increased in pregnant women with URSA than when compared to normal pregnant and non-pregnant women (6). This association correlated with the secretion of other inflammatory cytokines (14). To study the expression of IL-17 in women that have undergone abortion, we suggested that the activation of IL-17 could increase the expression of NF-κB, thereby reducing the number of ...
Recurrent pregnancy loss (RPL) isnt really a popular topic and not something I thought I would experience after having trouble getting pregnant. Who knew that getting pregnant was only a small step in the right direction?. Recurrent pregnancy loss is a distinct disease from infertility and is defined by two or more failed pregnancies. Some people experience both infertility and loss, like me, and others experience one or the other.. For me, recurrent pregnancy loss and infertility are one and the same. They are what kept me from bringing a baby home from the hospital for seven long years. I am infertile and while IVF helped me conceive, I miscarried every time. Recurrent loss is the ultimate problem for me.. Most miscarriages are due to an abnormal embryo - an unlucky accident, with no underlying medical issue, unless your specific issue is age-related or egg quality related. But, if you have miscarried three times, it is quite unlikely that this is due to three abnormal pregnancies, but rather ...
Recurrent miscarriage, habitual abortion, or recurrent pregnancy loss (RPL) is three or more consecutive pregnancy losses. Infertility differs because it is the inability to conceive. In many cases the cause of RPL is unknown. After three or more losses, a thorough evaluation is recommended by American Society of Reproductive Medicine. About 1% of couples trying to have children are affected by recurrent miscarriage. There are various causes for recurrent miscarriage, and some can be treated. Some couples never have a cause identified, often after extensive investigations. About 50-75% of cases of Recurrent Miscarriage are unexplained. Fifteen percent of women who have experienced three or more recurring miscarriages have some anatomical reason for the inability to complete the pregnancy. The structure of the uterus has an effect on the ability to carry a child to term. Anatomical differences are common and can be congenital. In the second trimester a weak cervix can become a recurrent problem. ...
1 % of all pregnancies end in habitual/recurrent abortion. In about half of women with habitual abortions (HAB) hereditary or acquired (antiphospholipid antibodies) thrombophilia are observed. The investigators wanted to test whether antithrombotic treatment (Low-Molecular Weight Heparin, LMWH, ASA or both combined)would prevent these women from a subsequent abortion. Depending on thrombophilic status the women included in one of the three sub-studies: HABENOX 1 (mild, single thrombophilia), HABENOX 2 (no known thrombophilia), HABENOX 3 (moderate to severe thrombophilia, with combined thrombophilia or moderate to high titer antiphospholipid antibodies).. Study design: Randomised placebo controlled multicenter study.. Number of patients per study: 90 patients per group, 270 altogether.. Timetable: Starting 2/2002, finishing 31.12.2007.. Time frame: ,37 weeks of gestation and ,24, but ,37 weeks of gestation (premature). Treatment started before 7. gw.. HABENOX 1 and 2:. Study groups:. Group 1 : ...
There were 578 miscarriages with chromosome results. Of the subjects, 18% were obese at the time of miscarriage. The mean maternal age at miscarriage was similar between the obese and nonobese groups. Due to the high rate of maternal cell contamination in the prior miscarriages, only subsequent miscarriages with chromosome results were included in the primary analysis. Of the 117 subsequent miscarriages, the frequency of an euploid miscarriage among obese women was 58% compared with 37% of nonobese women (relative risk = 1.63; 95% confidence interval 1.08-2.47).. Conclusion(s): ...
No aspect of the immunology of pregnancy is more controversial than the subject of recurrent pregnancy loss, or, as it will be called here, recurrent spontaneous abortion (RSAb). Nor is there any...
Repeated two to three spontaneous pregnancy loss is termed as recurrent miscarriage. Although the causes of recurrent miscarriage differ from the causes of spontaneous miscarriage, the symptoms remain the same like in most miscarriages.
Recurrent pregnancy loss (RPL) can be defined as more than two to three consecutive miscarriages before 24 weeks gestation. A literature review was done to provide an evidence-based approach to RPL, identifying the risk factors and causes and also looking at the various special investigations that form part of the work-up and trying to assess which have been proven to be effective or of negative impact, and which of the management options lead to a better outcome. We concluded that the following special investigations should be part of the work-up for all patients with RPL: (i) genetic counselling and karyotyping of the abortus; (ii) anticardiolipin antibodies and lupus anticoagulant testing must be done on two occasions, 6 - 8 weeks apart; (iii) all patients qualify for a pelvic ultrasound scan and hysteroscopy; (iv) syphilis testing must be done routinely; and (v) testing of thyroid function and glucose monitoring/glycosylated haemoglobin (HbA1c) measurement must be done in all patients with ...
Institut Marquès has developed specific tests to detect and treat repeated miscarriages and thus provide the best service to our patients.
The pathophysiology of recurrent pregnancy loss (RPL) is still unknown in 50% of the cases. Herein we measure the expression of beta3 integrin subunit, a well-known implantation marker, in women with or without RPL and correlate it with the histological dating of the endometrial tissue. LH-timed endometrial biopsies were obtained from cases (RPL; n = 21, age 33.9+/-4.7) and healthy controls (n = 29; age 29.8+/-4.1) during the mid-secretory phase (post ovulatory day: 8 to 10). Endometrial samples were timed histologically according to Noyes criteria and underwent immunohistochemical staining for beta3 integrin expression. For statistical analysis the semi-quantitative HSCORE was assessed. Type I (beta3 negative in an out-of-phase endometrium) and Type II defect (beta3 negative in an in-phase endometrium) were also analysed. Statistical analysis was done with Student t-test, Mann Whitney U test, ANCOVA and chi square for trend. Significance was set as P < 0.05. The mean (SD) age in controls was lower
Abstract Previous studies have revealed that women with unexplained recurrent spontaneous abortions have a limited repertoire of inhibitory KI receptors (inhKIRs) and that the inhK..
Pregnancy loss is the one of the most common obstetrical complications. The majority of pregnancy losses are random or isolated incidences that in many cases are related to genetic abnormalities. However, 2-5 % of reproductive age women experience recurrent miscarriages.1,2 Recurrent pregnancy loss is typically defined as two or three or more consecutive pregnancy losses. Genetic, hormonal, metabolic, uterine anatomical, infectious, environmental, occupational and personal habits, thrombophilia, or immune disorders were reported as possible etiologies.3-6 Despite the many etiologies, a majority of women with recurrent miscarriage have no discernible cause. It has been postulated that immunologic aberrations may be the cause in many of such cases. Immunopathological evaluation of placenta from women with recurrent pregnancy losses of immune etiologies often demonstrate increased inflammatory cell infiltration at the implantation site and increased fibrin deposition on deciduas and/or perivillous
Recurrent pregnancy loss (RPL) is generally defined as having had three or more consecutive pregnancy loses prior to 20 weeks gestation. RPL affects between 3% and 5% of couples. RPL becomes more prevalent with increasing female age, with an incidence of 10% to 15% in women in their twenties, rising to over 33% for women in their forties. In at least 50% of miscarriages, the fetus is chromosomally or genetically abnormal. It is natures way of preventing an abnormality. Genetic abnormalities of the embryo may occur due to chance or occasionally secondary to chromosome aberrations in the parents. Other causes of RPL include abnormalities in the shape of the uterus. These uterine abnormalities may be due either to an abnormality present at birth, or caused by benign tumors such as fibroids. Miscarriages may also occur as a result of intrauterine scarring caused by surgery and/or infections. In a small percentage of cases, antiphospholipid antibodies may be found in the maternal blood causing ...
Objective To study the local expression of membrane tissue CD4,CD8 immune cells and TM,PAI-1,F_(1+ 2),D-dimers coagulation related factors in unexplained recurrent spontaneous abortion patients and their relevance,so to provide help for the treatment of patients with unexplained abortion. Methods The CD4/CD8 cells were counted and the CD4/CD8 ratio was calculated by immunocytochemistry. Using enzymelinked immunosorbent assay and adsorption test method in 50 patients with unexplained abortion( experimental group,non-pregnant) for plasma thrombomodulin( TM),plasminogen activator inhibitor-1( PAI-1),prothrombin fragment F_(1+ 2),D dimer( D-dimer,D-D) and the normal pregnancy factor concentration,and 50 women( control group) as control,the expression of the above two groups factors in two groups were measured,and then compared the results. Results Compared with the control group,TM,PAI-1 and F_(1+ 2) were highly expressed,and the expression of D-D was low. The difference between the two groups was
According to the American Society for Reproductive Medicine (ASRM), recurrent pregnancy loss is when a woman has two or more miscarriages (clinical pregnancies) before 20 weeks gestation.. Possible Causes:. ...
This is all about avoiding success after recurrent pregnancy loss time that your body releases eggs from your ovaries, which normally happens in the middle of your pregnxncy. The main sources for this hub are the United States Department of Agriculture (USDA) Nutrition Program and WebMd. Though Prwgnancy think at 41 years of age, I can hang up the pram. Being a mother is truly a rewarding journey; pregnncy, trials and hardships can never be avoided as they are inevitable. and Zoosk, for example, offer mobile dating where you can log in securely from your smartphone. It may help kids that are suffering in foster homes and recurrrent that they are forgotten. You could also start your own family-oriented social group by inviting all your single-parent friends and their children to some event, such as a picnic or a day at the zoo. Headaches are the result of increased blood circulation caused by pregnancy hormones. Theres the option of displaying onscreen notices, or suspending play when these ...
Find valuable recurrent pregnancy loss information and solutions with Family Fertility in Lehigh Valley, PA - seek advice from an experienced gynecologist.
What are the effects of treatments for unexplained recurrent miscarriage? What are the effects of treatments for recurrent miscarriage caused by antiphospholipid syndrome?
Robertsonian translocation is one of the major chromosomal re-arrangements and constitutes 18% of all genetic abnormalities with an incidence of 1/1000 in the general population. Re-arrangements between homologous chromosomes are very rare and mainly manifest as monosomic or trisomic offspring. A couple was referred to our center with a history of eleven consecutive spontaneous abortions. The father was diagnosed as having 15;15 Robertsonian translocation. Fluorescence in situ hybridization analysis (FISH) was applied on sperm cells and resulted in only nullisomy and disomy for chromosome 15 that leads to monosomy or trisomy 15 in case fertilization occurs. Therefore the couple was counselled extensively on the risk of a future pregnancy. Furthermore they were informed that they would not benefit from preimplantation genetic diagnosis and sperm donation and adoption could be the only solution ...
Aspirin (acetylsalicylic acid) has been used ever since the Antiquity for its painkilling and anti-inflammatory effects. Its antiplatelet properties have then extended its indications to the field of coronaropathy and vascular cerebral disease, and finally to vascular placental disease. Aspirin has been widely prescribed since the 1980s to prevent pre-eclampsia, intra-uterine growth retardation and fetal death of vascular origin. It has also been proposed to prevent unexplained recurrent miscarriages. Its use during pregnancy is considered as safe, provided the daily doses do not exceed 100mg. Aspirin has been proven efficient to prevent pre-eclampsia and fetal growth restriction in high-risk patients. The benefits of prescribing aspirin have been demonstrated neither for vascular placental disease prevention in low risk patients, nor in cases of unexplained recurrent miscarriages.
Next article in issue: Should We Re-Examine the Status of Lymphocyte Alloimmunization Therapy for Recurrent Spontaneous Abortion? Next article in issue: Should We Re-Examine the Status of Lymphocyte Alloimmunization Therapy for Recurrent Spontaneous Abortion? ...
Principal Investigator:JUJI Takeo, Project Period (FY):1989 - 1990, Research Category:Grant-in-Aid for General Scientific Research (A), Research Field:Obstetrics and gynecology
Hi ladies, just going through my 4th MC. Its heart breaking but I have been referred to St Georges recurrent miscarriage clinic in Tooting. Has anyone had any experience of this clinic and any advice they would like to share? Im considering Dr Shehata but thought I would give my NHS clinic a go, especially as I can get an appt this Thursday. Many thanks
What is the best evidence-based treatment for recurrent miscarriages? The answer may surprise you!. Anyone who has struggled to become pregnant or stay pregnant knows how stressful it can be getting through the first trimester. It is so exciting to get that positive pregnancy test, but then you wait on pins and needles to make it through the first trimester, knowing that your chance for miscarriage drops dramatically once you do. Even then, for women who took a while to conceive or who have a history of pregnancy losses, it can be hard to let go of the worry and enjoy their pregnancy.. A paper published in the journal, BMC Complementary and Alternative Medicine, an open access, peer-reviewed journal, reviews the current evidence-base for commonly used treatments for recurrent miscarriage. It also makes a compelling argument for the use of acupuncture, not only in the case of recurrent miscarriage, but also in the case of a threatened miscarriage (light to heavy vaginal bleeding in early ...
The study, by medics at University Hospitals Coventry and Warwickshire (UHCW) NHS Trust and Warwick Medical School, pinpoints how body clock genes are temporarily switched off in the lining of the womb to allow an embryo to implant. Timing of this event is critical for pregnancy. The researchers examined endometrial cells from womb linings of healthy women, and also biopsies from women who had sadly suffered from recurrent pregnancy loss. The study has found that women suffering from recurrent miscarriages may be less able to regulate clock genes in the lining of the womb. The study also provides new insights into how night and shift work could affect female fertility. It is hoped that by identifying the causes behind recurrent miscarriages, that fertility experts will be able to help more prospective parents than ever before. It could have major implications for IVF, as the findings suggest that fertility specialists could, in future, target bio-rhythms in the womb to improve the environment ...
Among women who are aware of their pregnancy, the rate of spontaneous abortion-or miscarriage-is 15 to 20% and typically occurs during the first 7 weeks. Despite these troubling statistics, the cause of recurrent spontaneous abortion remains elusive. Now, a new study by Tavakoli et al. on the effects of vitamin D during early pregnancy may shed light on a new approach to the evaluation and management of women who suffer repeated miscarriages.. Researchers have identified several mechanisms behind spontaneous abortions, such as anatomical uterine abnormalities or the presence of specific maternal antibodies. However, women who do not display these conditions also struggle with recurrent and unexplained miscarriage, leaving this subset of infertility patients with few explanations and options. Attention has recently turned to the endometrial lining as a cause, specifically the interface between the early embryo and the cells programmed to assist in implantation. The authors examined the role that ...
Can PCOS contribute to a miscarriage?. Polycystic ovary syndrome (PCOS) has been shown to increase the rate of miscarriage in natural conceptions. By using infertility treatment to balance your hormones, the probability of miscarriage can be reduced.. What are the chances of getting pregnant after a miscarriage?. Your chances will vary. If you have been trying for over 6 to 12 months without success, you should consider infertility treatment. If you have had two or more consecutive miscarriages, you should go through a complete work-up to evaluate recurrent pregnancy loss. A high percentage of women who have had two miscarriages go on to conceive successfully.. Does the probability of having another miscarriage go up after one miscarriage?. Having one miscarriage does not necessarily mean you will have another one. The risk may be there but many causes can be overcome successfully with modern infertility treatment at leading fertility clinics, such as Pacific Reproductive Center in Los ...
The therapy depends on the cause. If the cause is uterine the therapy is surgical (elimination of fibroids or obstacles inside the uterus such as polyps, fibroids, malformations, internal scarring and adhesions; circleage in pregnancy); if the cause is hormonal the hormones that are lacking can be administered (sometimes there is a deficit of the thyroid hormones); if the cause is immunological the therapy can be based on cortisone, aspirin, and more rarely immunoglobulin. The results are often good.. ...
title:Role of Uterine Shape and Volume Abnormalities in Recurrent Pregnancy Loss (RPL). Author:Satyanarayana A Kongathi, Pratixa Z Chaudhari, Jigisha U Chauhan, Priyanka C Patel, Akshay M Chaudhari. Keywords:Uterine volume, Recurrent Pregnancy Loss, Sonography. Type:Original Article. Abstract:Background: Certain uterine factors like bicornuate, unicornuate and septate uterus being prime examples are more predictably associated and repeated pregnancy loss. These can be accurately investigated by HSG, 2D Transabdominal Sonography and Transvaginal Sonography. Methodology: The present study is a cross-sectional study conducted on the patients of Recurrent Pregnancy Loss (RPL) with history of two or more abortion with no live issue coming to the Outdoor Patient Department (OPD) of Sheth K.M.School of Post Graduate Medicine and Research, Ahmedabad. The study was based on the interview consisting of preformed questionnaire with the cases of RPL followed by the detail investigation by ...
What is the repeated miscarriages?. Spontaneous abortion means loss of pregnancy without external intervention, said by legalarmist before the fetus has reached viability. All pregnancy loss from the time of fertilization to 22 weeks of pregnancy, therefore, belong under the concept of length miscarriage. Repeated miscarriages is defined as three or more miscarriages in a row.. Involuntary abortion - also called spontaneous abortion-unfortunately happens quite often. Between 25 and 30 couples find that one or more pregnancies ends with a miscarriage. Although 15% of all identified pregnancies ending in miscarriage, so the total number is estimated to be closer to 50%. Most of the undiscovered abortions happening so early in the pregnancy, the woman has not yet reached to discover that she is pregnant. In 10-12% of all pregnancies occur abortion so late that a foster facility can be accessed by an ultrasound scan. In these cases it is most often necessary with medical induction of abortion or a ...
Abstract Prospective evaluation of 155 couples with two or more consecutive pregnancy losses disclosed uterine morphologic abnormalities in 27\%, chromosomal abnormalities in 21 in..
Recurrent Miscarriage: Definitions vary but most would agree it describes a situation where you have had four or possibly three consecutive miscarriages. The chance for any one pregnancy to miscarry is one in six, for two it is one in thirty-six. It can be tempting to rush into having detailed tests after two miscarriages, especially if you have not had any pregnancies that have resulted in a healthy baby. However the chance that a cause will be found is remote and the chance of a treatment being effective is even more remote. Many hospitals now run a recurrent miscarriage clinic. A figure often quoted is that if you have had four pregnancies and all have miscarried, you are still more likely to have a baby at term in the fifth pregnancy than another miscarriage ...
In a new trial which began last month, Dr Quenby plans to test these results by giving half of the women she recruits a dummy placebo and the rest a dose of the steroid. Prednisolones side effects include mood swings and increased appetite. However, most women would need to take it for just three months.". I suggest that it is important that any women who get prescribed for this problem be clearly informed that they need to cut out salt and salty food while taking this steroid drug, otherwise they are at great risk of fluid retention and consequent avoidable weight gain. - The fluid retention/weight gain is responsible for the mood swings and increased appetite and can be avoided by sticking to low salt intake. This would also lower the risk of developing many other health problems.. See Sodium in foods. and prescribed steroids and HRT. ...
Recurrent miscarriages or recurring pregnancy loss are a common occurrence for many who are trying to conceive. Ways to understand recurrent miscarriage include testing and a consultation with a doctor. An action plan and communicating with each other can help partners who experience recurring pregnancy loss cope with the psychological trauma of this event.
Chinese Medicine has always recognised that it is often the same sorts of imbalances that can cause difficulty in falling pregnant and difficulty in staying pregnant. The types of diagnoses a Chinese medicine practitioner makes in the case of recurrent miscarriages are very similar to those which describe different categories of subfertility.. Traditionally Chinese medicine would diagnose the nature of the recurrent miscarriage according to the constitution of the female partner. Nowadays, in light of new knowledge, the male partner will be assessed too. Ideally, we would treat the woman (and possibly her partner) for 3-6 cycles before she attempted to conceive again, but obviously there is frequently the pressure of time ticking by once the woman is late 30s or into her 40s.. The diagnoses are:. ...
Trying to get pregnant after a miscarriage is an emotional journey. If a woman has suffered several miscarriages, the journey has taken a toll on both her body and her spirit. Often, questions of why and how are being asked - is it because of my egg quality? is there a genetic incompatibility? is there something wrong with my uterus? what about immunological or blood clotting factors? endocrine or thyroid reasons? am I really "unexplainable"?. There is one more very important factor which is often overlooked - how is your Heart handling the ups and the downs of your pregnancies and your losses? have you put up an emotional shield of self-defence so that you do not feel the pain? do tears fall frequently and uncontrollably? how is your emotional stability during the day, and are you having any bad dreams? have you acknowledged and grieved for your loss? have you accepted the experience that youve had, and are you open and ready to invite a new experience in? are you able to forgive yourself? can ...
Scientists have discovered an enzyme that acts as a fertility switch, in a study published in Nature Medicine today. High levels of the protein are associated with infertility, while low levels make a woman more likely to have a miscarriage, the research has shown.. The findings have implications for the treatment of infertility and recurrent miscarriage and could also lead to new contraceptives. Around one in six women have difficulty getting pregnant and one in 100 women trying to conceive have recurrent miscarriages, defined as the loss of three or more consecutive pregnancies.. Researchers from Imperial College London looked at tissue samples from the womb lining, donated by 106 women who were being treated at Imperial College Healthcare NHS Trust either for unexplained infertility or for recurrent pregnancy loss.. The women with unexplained infertility had been trying to get pregnant for two years or more and the most common reasons for infertility had been ruled out. The researchers ...
The purpose of this study was to analyse whether the rate of pregnancy losses before the 24th week of gestation can be reduced by dalteparin treatment in
repeated second trimester loss...trying to find reasons. Questions about miscarriage and fertility deserve honest answers, so call Braverman IVF & Reproductive Immunology today!
We have done extensive testing with multiple specialists to try and solve this problem, but have had no luck. Weve tried everything from progesterone in all 3 forms (pills, suppository and injections) to heparin injections to chromosomal testing on both of us and on fetal tissue to an angiogram, etc, etc.. Through all this, we have received no answers. Nothing. Which is probably the most frustrating part of it all.. Miscarriage is something most women dont talk about, but when it happens over and over again, you need to talk about it. Its such a roller coaster of emotions and hormones that if you dont talk about it or have a great support system, you can feel so alone. I have been blessed to have such great support from Kyle, both of our families and a few close friends.. With each unsuccessful pregnancy, we wonder if we should shift our focus to preventing. I cant continue on this path much longer. Permanent contraception during the most fertile time in your life is not an easy decision to ...
Thirty-two women experienced recurrent spontaneous abortion (Table I.) Ultrasonographic finding of the 32 pregnancy losses included 15 (47%) empty embryonic gestational sacs or blighted ova and 17 (53%) intrauterine deaths after establishment of cardiac activity in the first trimester of pregnancy. Eight of the blighted ova occurred in women receiving IVIg and 17 in those receiving placebo. Of 17 intrauterine embryonic deaths, 3 (18%) occurred in women receiving IVIg and 14 (82%) in women receiving placebo. Among the 11 pregnancy losses occurring in women receiving IVIg, 8 (73%) were blighted ova, and 3 (27%) were intrauterine embryonic deaths. Twenty-one pregnancy losses occurred in women receiving placebo; 7 (33%) were blighted ova, and 14 (67%) were intrauterine embryonic deaths. The difference in intrauterine embryonic deaths between women receiving IVIg and placebo was significant (P,0.004, odds ratio 0.1). Complications. No reactions to study medications occurred. One infant was born with ...
Why do i only have bad back ache in the morning? I have bad back pains only in the mornings before getting out of bed. - Early pregnancy back ache when i get up in.Food, drug, insect sting allergy, and anaphylaxis Peanut, milk, and wheat intake during pregnancy is associated with reduced allergy and asthma in children.During early pregnancy a woman may feel exhausted and show lack of appetite but to keep one. A diet plan for pregnant women must be cleverly thought of and.. Prediction of early pregnancy maternal thyroid impairment in women affected with unexplained recurrent miscarriage. Human Reproduction, Jun 2011.Thyroid function in pregnancy. Screening for thyroid function in early gestation: should it be routinely performed on everyone? What tests are appropriate?.FRENCH RECOMMENDATIONS ON THE MANAGEMENT OF INVASIVE CERVICAL CANCER DURING PREGNANCY. Morice P1,. patients with early stage disease.OVIDAE AND CAPRIDAE CHAPTER 2.7.1. stage of pregnancy, but is more common in fetuses infected ...
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Purpose The vascular endothelial growth factor A (VEGFA) is crucial for normal vasculogenesis and angiogenesis during pregnancy, and alterations in the VEGFA gene expression were detected in women with idiopathic recurrent spontaneous abortion (IRSA) and spontaneously aborted conceptuses. Our aim was to evaluate whether there is an association between the functional −2549 insertion/deletion (I/D) polymorphism in the promoter region of the VEGFA gene and IRSA in reproductive couples. Methods We performed a case-control study involving 149 women and their 140 partners with three or more IRSA and 149 control women and men. Allele-specific polymerase chain reaction was used for genotyping. Results We found no association of the −2549 I/D polymorphism with IRSA in women. However, men with the DD genotype have a 1.75-fold increased risk of IRSA compared with men carrying the ID and II genotypes (95 % confidence interval (CI)=1.05-2.93, P=0.032). In addition, the D allele in men contributes to a ...
We retrospectively evaluated 66 patients younger than 40 years of age who presented with acute nonhemorrhagic cerebral infarction (n = 63) or transient ischemic attacks (n = 3) to determine the possible etiology and long-term outcome at a mean follow-up interval of 3 years after initial presentation. A probable cause for the stroke was identified in 24 patients (36%); this group included one woman with a history of recurrent spontaneous abortions and a positive test for the presence of the lupus anticoagulant. We performed detailed hemostatic investigations at follow-up in 38 (90%) of the remaining 42 patients in whom the cause of the stroke was unknown or uncertain; results of the basic hemostatic screening tests (including that for fibrinogen) were uniformly normal. All 38 patients demonstrated a normal fibrinolytic response as measured by tissue plasminogen activator release to a standard venous occlusion stress test; concentration of the inhibitor of tissue plasminogen activator was not ...
The American Journal of Reproductive Immunology (AJRI) is the official journal of the American Society for Reproductive Immunology. Its aim is the accurate and fast presentation of new data in reproductive immunology. The journal covers a variety of subspecialty topics, including fertility immunology, pregnancy immunology, immunogenetics, mucosal immunology, immunocontraception, endometriosis, recurrent spontaneous abortion, and autoantibodies.. 5 Year Impact Factor: 3.013 - Now Ranked in the Top 10 in Reproductive Biology ...
Like most hardworking people, you in all probability like beginning your day with a strong cup of coffee. Dumb I know and I am currently not working. I do know my body likes to over react and have nausea and bizarre eating habits……. Listed below are some things which may assist. Chance of successful pregnancy after recurrent miscarriage the books page for good e-book choices. Lower backaches are common early music headphones for pregnancy your pregnancy and as your child grows and you might be carrying extra weight, bubbling sounds in stomach during pregnancy pain might enhance. You may also expertise misgivings and bouts of weepiness or temper swings. Discomforts and Issues. Lower unfavorable suggestions off politely but instantly. Most others will cease after a fetal heartbeat is detected since hCG ranges differ enormously and doubling begins slowing down. But with every subsequent baby (there were 7!), I definitely bought wiser and discovered to waft. Effects of 1,2-propanediol and ...
Question - Prescribed etrogestan to take if pregnant, on heparin, aspirin. Any problems if taken together ?. Ask a Doctor about diagnosis, treatment and medication for Habitual abortion, Ask an OBGYN, Gynecologic Oncology
Gestanin (Allyloestrenol) is a progestogen structurally related to progesterone that has been given in threatened and habitual abortion, and to prevent premature labour.

Gestanin may al...
The Structural Causes of Recurrent Miscarriages include Uterine Septum and Fibroids. Our New York Fertility Surgeon can help you conceive.
Recurrent Miscarriage at SpringCreek Fertility Clinic. Dayton, Lima, Cincinnati and Columbus, OH, Northern KY and Eastern IN - Visit us today!
Dr. S.K.Biswas, Doctor for Heavy Bleeding and meopausal problem in Kolkata, specialist in recurrent Miscarriages, Menopausal problems, etc. now Practising at ruby General Hospital, Woodlands Hospital, Genesis Hospital, R.N.Tagore Hospital in Kolkata, India.
Inflammatory immune response plays a key role in reproductive failures such as multiple implantation failures (MIF), early pregnancy loss, and recurrent pregnancy losses (RPL). Cellular immune responses particularly mediated by natural killer (NK), and T cells are often dysregulated in these conditions. Excessive or inappropriate recruitment of peripheral blood NK cells to the uterus may lead to cytotoxic environment in utero, in which proliferation and differentiation of trophoblast is hampered. In addition, inadequate angiogenesis by uterine NK cells often leads to abnormal vascular development and blood flow patterns, which, in turn, leads to increased oxidative stress or ischemic changes in the invading trophoblast. T-cell abnormalities with increased Th1 and Th17 immunity, and decreased Th2 and T regulatory immune responses may play important roles in RPL and MIF. A possible role of stress in inflammatory immune response is also reviewed. ...
How Do I Start? - Instructions for ordering testing from Nora or for contacting Nora to discuss treatment alternatives. Please also participate in our discussion board if you would like to share with and learn from other interested people. An Overview of Recurrent Miscarriage Over a million women aged 15-44 suffer from recurrent miscarriage in the United States alone. We estimate that every year slightly fewer than 10% of those women are actively engaged in trying to conceive and bear children without success. For these women, miscarriage is a frustrating and repetitive outcome of pregnancy. Recurrent miscarriage is defined formally by the American College of Obstetrics and Gynecology (ACOG) as three or more miscarriages within the first 20 weeks of gestation, and not necessarily consecutive. The risk of miscarriage after two miscarriages is statistically very high; therefore ACOG recommends testing to determine the cause of the miscarriages after the second one, especially if the mother is over ...
SmileBaby IVF: Provides Pregnancy Loss Evaluation,Evaluating the Recurrent pregnancy loss by spontaneous abortions by Infertility Specialist In HRBR Layout.
Women who have had recurrent miscarriages should be checked for a tendency to develop blood clots as treating the condition halves their risk of further pregnancy loss, a new study has found.. Australian researchers followed 220 couples who had had at least three miscarriages.. They found that screening the women for thrombophilia, a tendency to develop blood clots, and giving them prophylactic anti-thrombotic therapy halved their future chances of losing a pregnancy.. Professor of obstetrics and gynaecology at the University of Adelaide, Gus Dekker, says the women were screened for thrombophilia, insulin resistance and elevated homocysteine levels. "We found that if you do nothing, these women can expect a 30% to 35% chance of a further miscarriage," he says. "But if you treat them, the pregnancy loss rate is halved to 15%. There is light on the horizon for women who have recurrent miscarriages as proper analysis and treatment can increase the chance of having a healthy baby from 70% to ...
PPAR Research is a peer-reviewed, Open Access journal that publishes original research and review articles on advances in basic research focusing on mechanisms involved in the activation of peroxisome proliferator-activated receptors (PPARs), as well as their role in the regulation of cellular differentiation, development, energy homeostasis and metabolic function. The journal also welcomes preclinical and clinical trials of drugs that can modulate PPAR activity, with a view to treating chronic diseases and disorders such as dyslipidemia, diabetes, adipocyte differentiation, inflammation, cancer, lung diseases, neurodegenerative disorders, and obesity.
Dr. Carson responded: Varies. Many causes including a clotting disorder (|a href="/topics/antiphospholipid-antibody" track_data="{
You probably know kudzu as a weedy vine, but it what to expect weekly pregnancy calendar a useful herbal drug as nicely. It offers a realistic account of what pregnancy is like from morning illness to birth and past. Going into premature labour would not at all times imply that your baby goes to pregnancy scan 7 weeks no heartbeat born there and then. Dont be upset if you arent getting pregnant the primary time. As well as, your infertility counselor could be an essential liaison when you have any questions, considerations, or points together with your therapy. Some women undergo repeated miscarriages, which are often as a result of immune problems, genetic problems, hormonal problems, or occasionally, a uterus thats slightly misshapen. Both placenta previa and placental abruption may cause heavy bleeding of vivid red blood from the vagina. Writing about these tales has been arduous work; every of my three books of chiropractic tales from the coalface took five years from inspiration to the ...
Preimplantation genetic screening (PGS) for aneuploidy was first reported by Verlinsky et al (1995) and Munne et al (1995). Both of these initial studies analysed polar bodies. The aim of the technique is to help determine the best IVF embryo for transfer on the grounds of the polar body or embryos chromosomes, by performing biopsy and analysis of the chromosomes using FISH (fluorescence in situ hybridisation). There have been hundreds of papers on the use of PGS. It is well known that for patients with advanced maternal age, there is an increased risk of chromosome abnormalities in the embryos they produce. Therefore this has been the main indication for PGS, but other indications include repeated IVF failure, repeated miscarriage (with normal karyotypes in the parents) and severe male factor infertility. As with many new technologies brought into the IVF clinic, there has been little evidence-based medicine to show that PGS increases delivery rates. At the late breaking news at the 2007 ...
Other sorts here of endoscopies utilized to analyze signs incorporate: bronchoscopy - used to look at the airways In case you have a persistent cough or youre coughing up blood hysteroscopy - used to look at the inside on the womb (uterus) if you will discover difficulties such as strange vaginal bleeding or repeated miscarriages cystoscopy - utilised to examine the inside of your bladder if youll find issues which include urinary incontinence or blood with your urine endoscopic ultrasound - utilized to develop photographs of internal organs, like the pancreas, and choose tissue samples Therapeutic ...
Factors in repeated miscarriages are more likely to Select. be. deal. grow. hormonal imbalance or an abnormality of the womb. The uterus may have two horns instead of one cavity and there is less room for baby to Select. be. deal. grow. . Previous womb infections or PID - pelvic inflammatory disease, where the genital organs are damaged and scarred, can also Select. be. deal. grow. a cause. Babies in the wrong place - in the confined space of a Fallopian tube, which normally conducts the egg from the ovary to the uterus - miscarry around six to ten weeks. This is an ectopic pregnancy. One in 140 pregnancies are ectopic and are more common in women over the age of 30. ...
For prenatal diagnostic testing, a chromosome analysis and a Fluorescent insitu Hybridisation or FISH test is performed.. FISH test: FISH provides a rapid result for confirmation or to determine if a pregnancy is affected by chromosome conditions such as Down syndrome, Edwards syndrome or Patau syndrome. Unlike chromosome analysis, FISH only looks at a small number of chromosome changes and results are available within 24-48 hours.. Chromosome analysis: A FISH test will always be followed by confirmatory testing either by a chromosome microarray or a conventional karyotype. These additional tests provide results in 8-14 days and can offer more information than the FISH test.. For the investigation of recurrent pregnancy loss and infertility a conventional chromosome analysis is performed. Results are typically available within 18 days.. ...
Moderated by Carolyn B. Coulam, MD Carolyn Coulam MD, specializes in helping those experiencing recurrent pregnancy loss and implantation failure. Dr. Coulam is a pioneer in the field of reproductive immunology. She is board certified in reproductive endocrinology and infertility. Dr. Coulam is a long-time advisor to INCIID and has been answering patient questions since INCIIDs inception. Dr. Coulams professional member profile is located here. Visit the Reproductive Medicine Institute (Chicago).
, who here has had surgery to remove a septum? I have had 2 children full term, followed by 3 consecutive miscarriages. After getting multiple different diagnosis on my uterine anomaly I finally sought help from a specialist. This dr. Tells me I have a slight fundal dip, with a 4cm septum and possible cervical septum. He reccomends corrective surgery for both issues and feels like this will have a positive effect. Can anyone share their stories about the procedure, good, bad and final pregnancy outcome?
Gregory KD, Ramos DE, Jauniaux ERM. Preconception and prenatal care. In: Gabbe SG, Niebyl JR, Simpson JL, et al, eds. Obstetrics: Normal and Problem Pregnancies. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 6.. Hobel CJ, Willaims J. Antepartum care. In: Hacker NF, Gambone JC, Hobel CJ, eds. Hacker & Moores Essentials of Obstetrics and Gynecology. 6th ed. Philadelphia, PA: Elsevier; 2016:chap 7.. Houry DE, Salhi BA. Acute complications of pregnancy. In: Marx JA, Hockberger RS, Walls RM, et al, eds. Rosens Emergency Medicine. 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 178.. Keyhan S, Muasher L, Muasher SJ. Spontaneous abortion and recurrent pregnancy loss. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 16. ...
Objective To compare live birth rates in women with recurrent pregnancy loss (RPL) and either autoantibodies or a coagulation abnormality, treated with low molecular weight heparin plus aspirin (LMWH/ASA) or ASA alone, and to place our results in context with other randomized clinical trials (RCT) with similar cohorts. Methods The HepASA Trial was an RCT including patients with a history of RPL and at least 1 of the following: antiphospholipid antibody (aPL), an inherited thrombophilia, or antinuclear antibody. Treatment groups were stratified by aPL status and history of early versus late pregnancy losses. Patients received either LMWH/ASA or ASA alone. The primary outcome was live birth; secondary outcomes included adverse events and bone loss at the spine and femoral neck. Literature over the past 20 years was reviewed to identify comparable RCT. Results Over 4 years, 859 women with RPL were screened: 88 (10.2%) fulfilled inclusion criteria, became pregnant and were randomized to receive ...
Consequences of reproductive aging include infertility, an increased likelihood of isolated spontaneous abortion (SAB), and likely an increased likelihood of recurrent pregnancy loss (RPL). ...
She explained how she came to the decision not to do heparin; doctors are split on using heparin when a patient presents as I do, with recurrent pregnancy loss but no history of blood clots. After consulting with other doctors in her clinic and the perinatologist (see previous post on finding out that bit of info), she feels that the benefits dont outweigh the risks of heparin at this point, since the literature and protocols dont point to it as the standard treatment. If I were homozygous (two affected genes) instead of heterozygous (one normal gene, one affected gene), the recommendation would be heparin. Or if I had two blood clotting abnormalities, heparin. Insurance wont cover heparin therapy at this point. She did say, though, that if I were to have another miscarriage, we would do heparin and insurance would cover. Of course we hope that the aspirin will do it. It stinks to go through the steps one at a time sometimes, but its helping us gain more information and rule things out at ...
So, Ive mostly been lurking with the occassional posting because I have a history of recurrent pregnancy loss and the early part of pregnancy is
Gynecologist consulting and Infertility specialist. Dr. DPankar Banerji is a qualified gynaecologist and IVF specialist and expert, completed his MBBS and Masters in Obstetrics and Gynecology from Medical College Jabalpur in 1989. He has special interest in reproductive endocrine and fetal medicine. He is managing 50-60 cycles of IVF and ICSI every month. He is working as medical director in this centre, specialised in reproductive endocrine and all IVF treatments since 1996 and has an expertise in treating recurrent pregnancy loss, endometriosis, menstrual disorders, fibroids and other reproductive problems.. He is member of Federation of Obstetric and Gynecological societies of India ( FOGSI), and European Society for Reproduction and Embryology(ESHRE), American Society of Reproductive medicine(ASRM), International Society of Ultrasound in Obstetrics and Gynecology(ISUOG) and life member of Indian Society of Assisted Reproduction(ISAR) and Indian society of Gynecological Endoscope. One of the ...
This study aimed to analyse the pregnancy outcomes in patients with TPO positivity after appropriate L-Thyroxin supplementation with close surveillance. All pregnant women attending the antenatal clinic at Milann-The Fertility Center, Bangalore, India- from Aug 2013 to Oct 2014 whose booking TSH was more than 2.5 mIU/L were included along with those pregnant women with prior hypothyroidism who were TPO positive. Those with TPO positive status were vigorously managed with appropriate thyroxin supplementation and the doses were readjusted every 3 to 4 weeks until delivery. Women with recurrent pregnancy loss were also tested for TPO positivity and if tested positive, were monitored serially with TSH and fT4 levels every 3 to 4 weeks and appropriately supplemented with thyroxin when the levels fluctuated. The testing was done after an informed consent in all these women. The statistical software namely SAS 9.2, SPSS 15.0, Stata 10.1, MedCalc 9.0.1, Systat 12.0 and R environment ver.2.11.1 were used ...
I called back and talked to the NP. She said my HCG levels had dropped to 16.8 and to stop all of my meds. She said I should get a period within 1-2 weeks, but perhaps sooner. I have to go back monday to get my HCG levels checked again. I asked about a RPL (Recurrent Pregnancy Loss) panel, but since this pregnancy is considered chemical, she didnt think insurance would cover the cost. She welcomed me to call the financial advisor to find out. She then said we could treat the next cycle as if I do have RPL issues. We will use Lovenox and probably add IV intralipids. Apparently these help to suppress the immune system ...
There are recommended lab tests after perinatal loss that a couple should consider if they have recently lost a baby and wanting to know why it occurred. Based on this is important to look at the causes of perinatal loss and provide results for recurrent pregnancy loss testing.
Expression of the mRNA of the inflammatory component of the immune response in the period of the expected window of implantation in women with recurrent pregnancy loss in the programs of assisted reproductive ...
Multiple miscarriage or recurrent miscarriage refers to the loss of two or more consecutive pregnancies. We look at what causes multiple miscarriages...
Miscarriages are awful things. The statistics on how many people have them are so high, its actually something like 1 in 3 (some women wouldnt even know). Its often not really talked about. For example, I mentioned it to the girls […]
Women who have had multiple miscarriages should see a doctor for testing for possible causes. Learn about the possible tests the doctor will perform.
I see Mr Akande ath the Bristol recurrent miscarriage clinic and he advised that the NHS do not fund this test. I have had it done privately now and they advised that you get the most accurate result by taking a biopsy from your womb at a certain time in your cycle. Mr Akande said that with the blook test for NK cells the results can vary due to lots of other factors and the only true result will be from a biopsy. Hope this helps x ...
Decidual Cast Miscarriage The miscarriage is a condition in which the fetus is pass out of body at the early stage of pregnancy i. "A woman will generally ovulate two to four weeks after a miscarriage, with a normal menstrual period occurring two weeks after ovulation," says Dr. Miscarriage Blood Clot Pictures by Pregnancy Weeks. Index Share. I had no symptoms of miscarriage, no cramping, no bleeding. I had a natural miscarriage in May 2010 at 11 weeks and a d/c in november 2010 at 9weeks. 20 Sep 2018- Stillborn babies, stillborn babies pictures, photos in loving memory baby loss ,our infants did exist if only for a short moment keeping their memories alive. The Edge radio host reveals miscarriage trauma. Your uploaded photos will appear here until they are carried into the folders above, to be held with babies of the same age. That our little man is going to be a big brother. I feel so overwhelmingly grateful that I am able to go on trips like this because of you guys!! So excited to share all ...
Dear Reader, Although nausea is a typical symptom of miscarriage, it typically doesnt last more than three days. In order to rule out any other health concerns that may be causing the nausea, its best to contact your health care provider. You havent mentioned whether or not a health care provider has diagnosed your miscarriage; if you havent yet sought care for your miscarriage, its strongly advised to seek out medical care as soon as possible to rule out any potential infections or other conditions that may be causing the nausea and vomiting. The variety of factors that cause miscarriages may contribute to the length of your symptoms as could some of the miscarriage treatments, so working with a professional to determine whats going on may help you figure out why youre still vomiting and feel better. Miscarriage is relatively common, with 15 to 20 percent of pregnancies estimated to end in miscarriage or a loss of the fetus before 20 weeks. One reason you may be feeling this way is that ...
If a woman miscarried several times before but never managed to give birth could be due to a lot of scar tissue or connective tissue at the site of attachment of the placenta. This happens because when the first child it was poorly cleaned. As a result, blood that is sent to the placenta is inadequate. Even before the developing fetus because they do not wilt or less get the food supply. Actually, the placenta was clever to find a good place and safe. But this trend may not occur and it becomes a problem. In addition, different problems will emerge during the first pregnancy when her mothers cervix rupture. Because, in the next pregnancy the cervix is not strong anymore fetal weight-bearing which is increasingly large. Such cases are usually resolved by way of the cervix with a suture hook Shirodkar - like a bag of money that way long ago closed by pulling the end of the rope. Pregnant women who have experienced this kind of action is not recommended to do coitus between husband and wife during ...
Carolyn B. Coulam, M.D., is an associate physician at Reproductive Medicine Institute and is Board Certified in the specialty of obstetrics and gynecology and in the subspecialty of reproductive endocrinology.
Has anyone been successful to prevent miscarriage using progrestrone pills? (of course for those who have had problems with recurrent miscarriage)
Lately, Ive seen a lot of discussion about miscarriages on a couple internet groups/boards Im a member of. Ladies asking about healing after miscarriage or discussing their fears of miscarriage or asking about symptoms of miscarriage. I keep thinking that I should share more about what happened to our family and how thats changed my point of view. Bear in mind, my point of view is very firmly grounded in my faith. If we had suffered this without our faith, Im fairly certain that I would not have made it through.}. My husband and I were married in April of 2010 and lost our first pregnancy to miscarriage in September 2010. We hadnt even been married six months and our relationship was being tested like nothing else. Losing a child, whether they are pre-born, still born, juvenile, or an adult can tear a marriage and a family apart. You tend to go into yourself and mourn. The world around you goes on but yours stops and you cant always understand why and how the rest of the world keeps ...
Anyone at my age trying to get pregnant again after a late miscarriage? I found out I was pregnant shortly after my 41st birthday. It was quite a shock but a nice one as I was told as I already had a healthy little girl aged 11 I was low risk but how wrong they wet. I had scans at 5,7,12,17 with every scan I questioned everything. Is my baby growing normally? Is everything where its supposed to be? I was assured every time baby id developing well and healthy. Even after being rushed in with a heavy bleed still baby scan said everything with baby is fine. My husband and I were excited going to our 20 week scan to find out if we would be buying blue or pink. after 20 mins we were told to go for a walk as baby was not in a good position to see every thing so I was scanned again then we were ushered into a side room where we were told some abnormalities had been detected and were refered to a specialist hospital. To our horror we were told our son was incompatable with life part of his brain was missing
A new study uses a special genetic sequencing technique to detect chromosomal abnormalities in couples with recurrent miscarriage.
Scientists in the UK have discovered a protein which helps embryos stick to the womb and improve treatments for recurrent miscarriages and pre-eclampsia, a pregnancy complication characterised by high blood pressure.
The disease Lupus is not well understood but having it can increase your risk of miscarriage. - Miscarriage and Lupus - Miscarriage at BellaOnline
ABSTRACT Introduction: To determine the relative frequency of gynecological pathologies in patients with recurrent pregnancy loss using combined hysteroscopy and laparoscopy, and to evaluate the potential of this combined strategy in the diagnosis of coexisting pathologies. Methods: Over 6 years, in a large referral infertility clinic and research centre in Tehran, 80 women with the diagnosis of recurrent pregnancy loss underwent hysteroscopy and laparoscopy. Results: Forty nine (61.3%) women had 3 episodes of miscarriage, 9 (11.3%) had 4 occurrence of pregnancy loss and 14 (17.5%) patients had experienced 5 abortions. Also, there were 4 (5%), 2 (2.5%) and 2 (2.5%) participants with 6, 7 and 8 miscarriages, respectively. Thirteen women (16.2%) had normal hysteroscopy, and in 52 (65%) participants laparoscopy did not reveal abnormal findings. Septate uterus and submucous myomas together, comprised 62 (77.5%) of the recognized pathologies in hysteroscopy. Of the 28 abnormalities found in ...
Background: Antiphospholipid syndrome (APS) is one of the causes of recurrent abortions and intrauterine death among pregnant women. This study was undertaken to find out the association between bad obstetric history (BOH) and anticardiolipin (aCL) antibody. Material and Methods: Blood samples were collected from women with BOH referred (recurrent abortion, intrauterine death, PIH) to a Tertiary Care Center in Chennai, Tamil Nadu. Blood samples from 100 pregnant women with BOH and 110 healthy pregnant women were collected and tested for the presence of aCL antibody by ELISA Method. Results: Among the 100 patients tested 21 (21%) were aCL positive; IgG was positive in 16 (76.19%) patients and IgM was positive in 5(23.80%) patients. Anticordiolipin antibody (aCL) positivity in BOH was statistically significant (p .0048) when compared to healthy pregnant women. There was a positive correlation (p 0.005) between IgG and BOH. The antibody titer was high in 12 (57.14%) and moderate in 6 (28.57%). ...
Selected Publications. Petri M., Rheinschmidt M., Whiting-OKeefe Q., Hellmann D., Corash L. (1987). The Frequency of Lupus Anticoagul-ant in Systemic Lupus Erythematosus: A Study of 60 Consecutive Patients by Activated Partial Thrombo-plastin Time, Russell Viper Venom Time, and Anticardiolipin Antibody. Ann Int Med, 106, 524-531.. Petri M., Golbus M., Anderson R., Whiting-OKeefe Q., Corash L., and Hellmann D. Antinuclear Antibodies, Lupus Anticoagulant, and Anticardiolipin Antibody in Idiopathic Habitual Abortion: A Controlled Prospective. Petri M., Spence D., Bone L.R., Hochberg M.C. (1992). Coronary artery disease risk factors in the Hopkins Lupus Cohort: prevalence, patient recognition, and preventive practices. Medicine, 71, 291-302.. Petri M, Perez-Gutthann S, Spence D, Hochberg MC. (1992). Risk factors for coronary artery disease in patients with systemic lupus erythematosus. Am J Med, 93, 513-519.. Petri M. (1995). Musculoskeletal Complications of Systemic Lupus Erythematosus in the ...
Pregnancies in women with systemic lupus erythematosus are recognized to result in excessive fetal morbidity and mortality. Maternal autoantibody status may explain some of these problems. Anti-cardiolipin antibody has been associated with recurrent pregnancy losses in some women with lupus, but the risk of these losses has not been defined. At...
This study investigated the association between the risk for spontaneous abortions and the job type of female semiconductor workers to assess their reproductive health. The risk for spontaneous abortion for female semiconductor workers was not significantly higher for FAB and PKG workers than for clerical workers according to their job held longest. However, when the analysis was stratified for the year of conception, we found significantly higher odds for spontaneous abortions (OR 2.21, 95% CI: 1.01-4.81) in PKG workers than clerical workers when the pregnancy occurred prior to 2008.. In this study, the spontaneous abortion rates for FAB and PKG workers were 12.6% and 14.5%, respectively; these were higher than the rate of 11.1% found in clerical workers. These spontaneous abortion rates for female workers involved in semiconductor production were higher than the spontaneous abortion rate of 11.1% reported for Korean domestic 15- to 44-year-old married women [18]. In 1988, Pastides et al. first ...
The second part describes the management of an incomplete evacuation of the uterus after misoprostol use for first trimester miscarriage. Although women with an incomplete evacuation are often relatively asymptomatic, a curettage is often performed. We conducted a randomized controlled trial, comparing curettage to expectant management. A cohort study was conducted alongside this trial following women who received treatment of their preference. These studies show, that although curettage is slightly more effective, expectant management is safe and also effective in at least 5 out of 6 women. Quality of life did not differ between randomized women, and in the cohort, women who underwent expectant management reported a slightly better quality of life. Furthermore, curettage does not seem cost effective over expectant management in women with an incomplete evacuation. In these studies we found no differences in subsequent pregnancy rates or pregnancy outcomes ...
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Results 215 pregnancies in 184 women were included and classified according to mothers autoimmune disease: 52 (24,2%) Primary Antiphospholipid Syndrome (PAPS), 26 (12,1%) with only Antiphospholipid Antibodies (APA), 27 (12,6%) Systemic Erythematosus Lupus (SLE), 28 (13%) SLE with APA, 44 (20,5%) Undifferentiated Connective Tissue Disease (UCTD) and 38 (17,7%) UCTD with APA. A total of 41 (19,06%) miscarriages were reported, 32 (14,8%) in the first 10 weeks of pregnancy and 9 (4.18%) beyond that 10th week. Risk factors for miscarriages in the univariate analysis were mothers age, lupus anticoagulant, IgG and IgM anticardiolipin antibodies, previous miscarriages and PAPS, while UCTD was a protective factor. In the multivariate model only mothers age (OR 0.9, IC 95% 0.8-0.98), lupus anticoagulant (OR 2.5, IC 95% 1.1-5.4), IgG anticardiolipin (OR 4.0, IC 95% 1.8-9.0) and previous miscarriages (OR 2.8, IC 95% 1.2-6.5) were predictors. A Miscarriage Risk Score ranging between 0 and 11 points was ...
The aim was to analyse reproductive outcome in pregnancy subsequent to a previous midtrimester pregnancy loss.. This was a retrospective case note review over a 4 year period. Patients who had a midtrimester pregnancy loss (,13 and,24 weeks gestation by ultrasound) were identified. A subgroup who achieved subsequent pregnancy formed the study group. The authors assessed their previous pregnancy loss, results of investigations and reviewed their care and outcome in next pregnancy.. Of the 86 patients who had midtrimester loss 56 (65%) had a subsequent pregnancy and formed the study group. Median age was 31 and 17 were nulliparous. Median gestation at midtrimester spontaneous abortion was 17 weeks. Pregnancy loss was classified as intrauterine fetal death (22), bleeding (11), fetal abnormality (9), cervical incompetence (6) and prelabour premature rupture of membranes (8). Investigation revealed two maternal thrombophilias, two fetal chromosomal abnormalities, two with two vessel cord and eight ...
Low Molecular Weight Heparin and/or Aspirin in Prevention of Habitual Abortion - Full Text View - ClinicalTrials.gov  Low Molecular Weight Heparin and/or Aspirin in Prevention of Habitual Abortion - Full Text View - ClinicalTrials.gov
1 % of all pregnancies end in habitual/recurrent abortion. In about half of women with habitual abortions (HAB) hereditary or ... Habitual abortion. recurrent abortion. hereditary and acquired. thrombophilia. preeclampsia. premature birth. miscarriage. ... Abortion, Habitual. Abortion, Spontaneous. Pregnancy Complications. Aspirin. Heparin. Heparin, Low-Molecular-Weight. Dalteparin ... Low Molecular Weight Heparin and/or Aspirin in Prevention of Habitual Abortion (HABENOX). The safety and scientific validity of ...
more infohttps://clinicaltrials.gov/show/NCT00959621
Recurrent Pregnancy Loss | Springer for Research & Development  Recurrent Pregnancy Loss | Springer for Research & Development
... recurrent spontaneous abortion (RSAb). Nor is there any... ... Unander AM, Olding LB: Habitual abortion: Parental sharing of ... Houwert-de Jong MH, Termijtelen A, Eskes TKAB, et al.: The natural course of habitual abortion. Eur J Ob Gyn Reprod Biol 1989; ... Cauchi MN, Tait B, Wilshire MI, et al.: Histocompatibility antigens and habitual abortion. Am J Reprod Immunol Microbiol 1988; ... Kleinhout J, Madan K: Repeated abortions and chromosome analysis, in Hafez ESE (ed): Spontaneous Abortion. Boston, MTP Press; ...
more infohttps://rd.springer.com/chapter/10.1007/978-1-4612-0361-2_6
Toxoplasmosis among women with habitual abortion  Toxoplasmosis among women with habitual abortion
Al Hamdani, Muna M. & Mahdi, Nadham K. (‎1997)‎. Toxoplasmosis among women with habitual abortion. EMHJ - Eastern Mediterranean ... The role of maternal toxoplasmosis as a risk factor for habitual abortion was investigated. The indirect haemagglutination test ... 2048 much more frequently in women with habitual abortion [‎18.5%]‎ than in the normal pregnancy group [‎5.9%]‎. The overall ... Determination of habitual physical activity by means of a portable R-R interval distribution recorder  Masironi, R.; ...
more infohttps://apps.who.int/iris/handle/10665/117384
Habitual Abortion or Recurrent Pregnancy Loss by Serageldin Ayman on Prezi  Habitual Abortion or Recurrent Pregnancy Loss by Serageldin Ayman on Prezi
Transcript of Habitual Abortion or Recurrent Pregnancy Loss. Habitual Abortion or Recurrent Pregnancy Loss. Definition. * ... Habitual Abortions or preterm labour.. *Any congenital malformations of the uterus.. McDonalds Operation. *The esthmus uteri ... Repeated Abortion: Repeated successive spontaneous abortion Maternal Causes. Immunological. Fetal Causes. Infections. ... Structural disorders maybe a cause 2nd trimestic abortion.. Syphilis. External Internal. Neoplastic. abdomen.. *Blow to the * ...
more infohttps://prezi.com/qb_im1ufnyb7/habitual-abortion-or-recurrent-pregnancy-loss/
Habitual abortion | definition of habitual abortion by Medical dictionary  Habitual abortion | definition of habitual abortion by Medical dictionary
... habitual abortion explanation free. What is habitual abortion? Meaning of habitual abortion medical term. What does habitual ... Looking for online definition of habitual abortion in the Medical Dictionary? ... Related to habitual abortion: incomplete abortion, threatened abortion, missed abortion, septic abortion ... habitual abortion. Recurrent abortion Obstetrics The loss of ≥ 3 consecutive pregnancies, or ≥ 3 spontaneous abortions with no ...
more infohttp://medical-dictionary.thefreedictionary.com/habitual+abortion
Progesterone Implantation in Habitual Abortion Archives | Hotze Health & Wellness Center  Progesterone Implantation in Habitual Abortion Archives | Hotze Health & Wellness Center
Braidwood Management, Inc. All Rights Reserved. The information on this website is provided for educational purposes only, and does not constitute any medical advice. By using this website you fully waive all legal claims based on any information contained herein, and fully agree to this disclaimer.. Copyright © 2018 Hotze Health & Wellnes Center. All Rights Reserved ...
more infohttps://www.hotzehwc.com/tag/progesterone-implantation-in-habitual-abortion/
Habitual Abortion and Group B Strep in Latest Research - Fertility Solution  Habitual Abortion and Group B Strep in Latest Research - Fertility Solution
Association of Habitual Abortion with Group B Streptococcus Genital-Tract Infection. Experiences with Intravenous Antibiotic ... It is suggested that Group B Streptococcus is one of the causes of habitual abortions. ... In habitual aborters, as of today, we have eleven successfully treated cases, where a normal pregnancy and normal delivery of a ... small series and does not establish a cause and effect relationship between Group B Streptococcus and habitual abortions, the ...
more infohttp://www.fertilitysolution.com/Latest-Research/Habitual-Abortion-and-Group-B-Strep.html
Habitual Abortion And Athraa : Tibb-e-Islami Dawakhana  Habitual Abortion And Athraa : Tibb-e-Islami Dawakhana
Habitual Abortion And Athraa. What is Habitual Abortion. Habitual abortion is a form of infertility. When miscarriage occurs ... Symptoms of Habitual Abortion. There are the two main symptoms of Habitual abortion. ... A woman who has suffered two or more terminations of this sort -consecutively is said to be a case of habitual abortion. ... Note: You can contact to Professor Hakim Dilshad Hussain for Further information about Habitual Abortion . ...
more infohttp://www.tibbislami.org/habitual-abortion-and-athraa/
Gravibinon Schering in the treatment of habitual abortion and prevention of abortion in uterus hypoplasticus]. - Semantic...  Gravibinon "Schering" in the treatment of habitual abortion and prevention of abortion in uterus hypoplasticus]. - Semantic...
... in the treatment of habitual abortion and prevention of abortion in uterus hypoplasticus]. by I Shurkalev et al. ... Gravibinon Schering in the treatment of habitual abortion and prevention of abortion in uterus hypoplasticus].. @article{ ... in the treatment of habitual abortion and prevention of abortion in uterus hypoplasticus].}, author={I Shurkalev and T Ananiev ...
more infohttps://www.semanticscholar.org/paper/%5BGravibinon-%22Schering%22-in-the-treatment-of-habitual-Shurkalev-Ananiev/afc6865baf8ddfe3901095d6c2c823775755ef0a
G.Georgopoulos Ob-Gyn - english protocol for  causes of Habitual Abortion Recurrent Pregnancy Loss RPL LIT  G.Georgopoulos Ob-Gyn - english protocol for causes of Habitual Abortion Recurrent Pregnancy Loss RPL LIT
Responsible for 50-60% of 1st TM abortion. ♦ Most common are aneuploidics, which are present m 80% of blighted ova and 5-10% ... RPL is defined as 3 or more consecutive spontaneous abortions before 20 wks of gestation or a fetal weight less than 500 gms ... The reproductive H/o patient is \ ery important as relative risk of abortion increases with no of previous pregnancy failures ... 2 Antiphosphohpid antibodies and investigation of recurrent Abortions M J Hewitt, S M Quenby, P N Baker ...
more infohttps://www.ob-gyn.gr/english-protocol-for-causes-of-Habitual-Abortion-Recurrent-Pregnancy-Loss-RPL-LIT.html
Infertility Glossary of Medical Terms  Infertility Glossary of Medical Terms
Habitual abortion:. A miscarriage occurring on two or more separate occasions. * Incomplete abortion:. ... Missed abortion:. A miscarriage in which a dead fetus and other products of conception remain in the uterus for four or more ... Complete abortion:. A miscarriage in which all of the products of conception have been expelled and the cervix is closed. * ... Selective abortion:. A term often used to refer to intentional termination of one or more gestational sacs within the uterus, ...
more infohttps://www.drmalpani.com/knowledge-center/resources/books/glossary
March 1959 - Volume 2 - Issue 1 : Clinical Obstetrics and Gynecology  March 1959 - Volume 2 - Issue 1 : Clinical Obstetrics and Gynecology
DIAGNOSIS AND TREATMENT OF THREATENING AND HABITUAL ABORTION. HASKELL, JACK G. HASKELL, JACK G. Less ... THE OUTCOME OF PREGNANCY COMPLICATED BY THREATENED ABORTION. NESBITT, ROBERT E. L. Jr. ... ENDOCRINE FACTORS IN THE ETIOLOGY OF SPONTANEOUS ABORTION. CORNER, GEORGE W. Jr. ... THE CONTROL OF THERAPEUTIC ABORTION IN A GENERAL HOSPITAL. McELIN, THOMAS W. ...
more infohttps://journals.lww.com/clinicalobgyn/toc/1959/03000
October 1956 - Volume 11 - Issue 5 : Obstetrical & Gynecological Survey  October 1956 - Volume 11 - Issue 5 : Obstetrical & Gynecological Survey
PATHOLOGY OF PREGNANCY SPONTANEOUS AND HABITUAL ABORTIONS. JAVERT, CARL T. JAVERT, CARL T. Less ...
more infohttps://journals.lww.com/obgynsurvey/toc/1956/10000
Homeopathy Medicines for A to Z Diseases  Homeopathy Medicines for A to Z Diseases
Homeopathy plays a very important role in treating habitual abortion Homeopathic treatment for habitual....... ... What is Habitual Abortion Habitual abortion is a form of infertility. When miscarriage occurs repeatedly at a certain period of ... For Treatment of Habitual Abortion in New Delhi Gurgaon Noida Faridabad NCR or Online Treatment of Habitual Abortion Contact Us ... Homeopathic Treatment of Habitual Abortion. Homeopathy plays a very important role in treating habitual abortion Homeopathic ...
more infohttps://ethoshealthcare.com/a_to_z_diseases/habitual-abortion/
Table of Contents - April 26, 1952, 1 (4764) | The BMJ  Table of Contents - April 26, 1952, 1 (4764) | The BMJ
Habitual Abortion Br Med J 1952; 1 :923 (Published 26 April 1952) ... Treatment of Septic Abortion Br Med J 1952; 1 :886 (Published 26 April 1952) ... Medico-Legal Aspects of Abortion Br Med J 1952; 1 :915 (Published 26 April 1952) ...
more infohttp://www.bmj.com/content/1/4764
Search of: tolonium chloride - List Results - ClinicalTrials.gov  Search of: tolonium chloride - List Results - ClinicalTrials.gov
Abortion, Habitual. Observational. *Northwell Health. Other. *Observational Model: Case Control. *Time Perspective: Cross- ...
more infohttps://clinicaltrials.gov/search/intervention=tolonium+chloride
Plus it  Plus it
... habitual abortions; parental exposure to mutagens or teratogens; decreased concentration of serum (alpha) fetoprotein in ... The rate of spontaneous abortion in the first trimester is estimated to be 99%, but this high rate of abortion can only ... We found a spontaneous abortion rate after amniocentesis of 8% (1% to 27%). If the rate of spontaneous abortions after ... induced abortion, spontaneous abortion, live birth). The register does not include information on the number of cells analysed ...
more infohttp://www.bmj.com/content/312/7022/16
The diagnosis - infertility | Sana-med  The diagnosis - infertility | Sana-med
Habitual abortion or impossibility of pregnancy bearing.. Regular pregnancy interruption is called the habitual abortion. ... Usually the abortion occurs during the period till 12 weeks, though, can also happen during later terms. Quite often the woman ... THE DANGER OF NOT DIAGNOSED ISTHMIK-CERVICAL INSUFFICIENCY IS THE RISK OF ABORTION ON LATER TERM - IN THE SECOND AND THIRD ... PREGNANCY BEARING BECOMES ALMOST IMPOSSIBLE DUE TO THE DAMAGE OF DEEP LAYERS OF ENDOMETRIUM AS A RESULT OF NUMEROUS ABORTIONS ( ...
more infohttps://sana-med.com.ua/en/diagnoz-besplodie.php
Recurrent Abortions Tips & Advice From Top Doctors | Lybrate  Recurrent Abortions Tips & Advice From Top Doctors | Lybrate
Experts Advice Around Recurrent Abortions. Read Articles on Recurrent Abortions from Top Doctors in India on Lybrate.com ... Abortion Habitual. Dr. Mrs Neeraj Gupta BHMS, Certificate in Gynaecology & Obestric, MD - Homeopathy, Ph.D Homeopathy ... Abortion is the expulsion of products of conception either fully or partially.. The causes of abortion vary from hormonal ... The right drug in the right dose and taken in the correct technique has higher success rate of a complete abortion. Incorrect ...
more infohttps://www.lybrate.com/topic/recurrent-abortions/health-feed/tips
  • While this has diminished the occurrence of septic abortions performed at the hands of unscrupulous abortionists and has improved the possibility of safe and uneventful physical recovery from an induced abortion, the issue remains controversial and charged with emotion. (thefreedictionary.com)
  • The objective of this study of patients with habitual abortion (HA), was to determine their autoimmune profile and to try to prevent new abortions using low-dose aspirin for 7 months with prednisone in the first trimester only, or with low-dose aspirin alone. (asklenore.info)
  • Abortions in the embryonic phase of fetal development were associated with a significantly higher incidence of maternal heterozygosity for FVL. (biomedsearch.com)
  • Usually the abortion occurs during the period till 12 weeks, though, can also happen during later terms. (sana-med.com.ua)
  • Women who have made a decision to have an abortion need a safe, non-judgmental environment to recover physically and emotionally from the procedure. (thefreedictionary.com)
  • The patient should know that other alternatives are available and that an abortion after 20 weeks is inadvisable for medical and other reasons. (thefreedictionary.com)