A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.
Long chain organic acid molecules that must be obtained from the diet. Examples are LINOLEIC ACIDS and LINOLENIC ACIDS.
A plant family of the order Taxales, class Pinopsida, division CONIFEROPHYTA.
FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds.
(2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)
An enzyme of the oxidoreductase class primarily found in PLANTS. It catalyzes reactions between linoleate and other fatty acids and oxygen to form hydroperoxy-fatty acid derivatives.
Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates. These products are then rapidly converted by a peroxidase to hydroxyeicosatetraenoic acids. The positional specificity of the enzyme reaction varies from tissue to tissue. The final lipoxygenase pathway leads to the leukotrienes. EC 1.13.11.- .
A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed)
An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.
Eighteen-carbon essential fatty acids that contain two double bonds.
A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes.
Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
20-carbon saturated monocarboxylic acids.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.
A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
... metabolize arachidonic acid to a set of products (the eicosatrienoic acid epoxides, abbreviated as EETs, which are classified ... Adrenic acid or 7(Z),10(Z),13(Z),16(Z)-docosatetraenoic acid, an abundant fatty acid in the adrenal gland, kidney, vasculature ... However, the CYP epoxygenases also metabolize other omega-6 fatty acids such as linoleic acid and the omega-3 fatty acids, ... 14Z-eicosatetraenoic acid. Certain CYP epoxygenases attack these double bounds to form their respective eicosatrienoic acid ...
Eicosatetraenoic acid, Heptadecane, He1adecanoic acid, methyl ester, Neophytadiene, n-He1adecanoic acid, Oleic Acid, Phytol, ... 15-Octadecatrienoic acid, 9,12-Octadecadienoic acid (Z,Z)-, methyl ester, 9-Nonadecene, Cholesterol, methyl ester, (all Z)- ... Phytol acetate, Stigmastan-3,5-diene, Tetracosanoic acid, methyl ester, Tetradecane, 2,6,10-trimethyl-, Tetradecanoic acid, Z-( ... 17-Octadecynoic acid, 1-Heptatriacotanol, 6,10,14-trimethyl- 2-Pentadecanone, 7,10-He1adecadienoic acid, methyl ester, (Z,Z,Z)- ...
It metabolizes arachidonic acid to the following eicosatrienoic acid epoxides (termed EETs): 5,6-epoxy-8Z,11Z,14Z-EET, 8,9- ... CYP2J2 also metabolizes linoleic acid to 9,10-epoxy octadecaenoic acids (also termed vernolic acid, linoleic acid 9:10-oxide, ... linoleic acid 12,13-oxide, or isoleukotoxin); docosahexaenoic acid to various epoxydocosapentaenoic acids (also termed EDPs); ... see epoxyeicosatrienoic acid, epoxydocosapentaenoic acid, and epoxygenase pages). Vernolic and coronaric acids are potentially ...
Mead acid, i.e. 5Z,8Z,11Z-eicosatrienoic acid, is an ω-9 fatty acid containing three cis double bonds, each located between ... Dihomo-gamma-linolenic acid (DGLA), 8Z, 11Z,14Z-eicosatrienoic acid is an ω-6 fatty acid with three cis double bonds, each ... Eicosapentaenoic acid (EPA), i.e.i.e. 5Z, 8Z,11Z,14Z,17Z-eicosapentaenoic acid is an ω-3 fatty acid with five cis double bonds ... Adrenic acid (AdA), 7,10,13,16-docosatetraenoic acid, is an ω-6 fatty acid with four cis double bounds, each located between ...
EETS are epoxide eicosatrienoic acid metabolites of arachidonic acid (a straight chain Eicosatetraenoic acid, omega-6 fatty ... 14Z-eicosatetraenoic acid. Cytochrome P450 epoxygenases attack these double bonds to form their respective eicosatrienoic acid ... 14Z-eicosatrienoic acid), 8,9-EET (i.e. 8,9-epoxy-5Z,11Z,14Z-eicosatrienoic acid), 11,12-EET (i.e. 11,12-epoxy-5Z,8Z,14Z- ... eicosatrienoic acid), or, as drawn in the attached figure, 14,15-EET (i.e. 14,15-epoxy-5Z,8Z,11Z-eicosatrienoic acid). The ...
18-dihydroxy-eicosatetraenoic acid (5,18-diHETE) or by a Δ6-reductase to form 5-oxo-18-hydroxy-eicosatrienoic acid (5-oxo-18- ... 19-dihydroxy-eicosatetraenoic acid (5,19-diHETE) or by a Δ6 reductase to 5-oxo-19-hydroxy-eicosatrienoic acid (5-oxo-19-HETrE ... Phospholipid-bound arachidonic acid → free arachidonic acid b) Free arachidonic acid + O2 → 5(S)-HpETE c) 5(S)-HpETE → 5(S)- ... and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid ...
sEH converts 17,18-EEQ isomers to 17,18-dihydroxy-eicosatrienoic acid isomers (17,18-diHETEs), 14,15-EEQ isomers to 14,15- ... see 20-Hydroxyeicosatetraenoic acid), i.e. 19-hydroxyhydroxyeicosatetraenoic acid and/or 20-hydroxyeicosatetranoic acid, take ... 13-epoxides isomers termed coronaric acids or isoleukotoxins. They metabolize the omega-3 fatty acid, docosahexaenoic acid, ... They metabolize the omega-6 fatty acids arachidonic acid, which possess four double bonds, to 8 different epoxide isomers which ...
"Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in ... Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω−6 fatty acid. (also called, cis,cis,cis-8,11,14-Eicosatrienoic acid) In ... Essential fatty acid Horrobin, D. F., 1990a. Gamma linolenic acid. Rev. Contemp. Pharmacother. 1, 1-45 Huang, Y.-S. and Mills, ... 1997). "Dietary supplementation with γ-linolenic acid alters fatty acid content and eicosanoid production in healthy humans". J ...
... sorbic acid MeSH D10.251.355.920 - trans fatty acids MeSH D10.251.400.092 - acetic acids MeSH D10.251.400.092.129 - acetic acid ... fatty acids, omega-6 MeSH D10.251.355.343.249 - gamma-linolenic acid MeSH D10.251.355.343.500 - linoleic acids MeSH D10.251. ... linolenic acids MeSH D10.251.355.310.640.400 - alpha-linolenic acid MeSH D10.251.355.310.640.425 - gamma-linolenic acid MeSH ... oleic acids MeSH D10.251.355.325.600.525 - oleic acid MeSH D10.251.355.325.600.780 - ricinoleic acids MeSH D10.251.355.325.919 ...
... eicosatrienoic acid and 13(R)-hydroxy-14(S),15(S)-epoxy-5(Z),8(Z),11(Z)-eicosatrienoic acid; these two products are novel ... 13E-eicosatetraenoic acid (15(R)-HpETE). Human cells release arachidonic acid (i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid) from ... a metabolite of arachidonic acid. Various cell types metabolize arachidonic acid to 15(S)-hydroperoxyeicosatetraenoic acid (15( ... Maas, R. L.; Turk, J; Oates, J. A.; Brash, A. R. (1982). "Formation of a novel dihydroxy acid from arachidonic acid by ...
오메가-6 지방산(영어: omega-6 fatty acid) 또는 ω−6 지방산(영어: ω−6 fatty acid) 또는 n−6 지방산(영어: n−6 fatty acid)은 공통적으로 n-6 위치에 탄소-탄소 이중 결합을 갖는 ... 그리고 세포 손상이 복구된 후, 염증의 해결 단계 동안 항염증성 분자(예: 리폭신 및 프로스타사이클린)의 생성으로 결국 이어진다.[4][5][6][7][8][9][10][11][12][13][14][15] ... 2007). "Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived ... "Effect of feeding systems on omega-3 fatty acids, conjugated linoleic acid and trans fatty acids in Australian beef cuts: ...
... eicosatrienoic acid) and b) hepoxilin B3 (10-hydroxy-11S,12Sepoxy-(5Z,9E,14Z)-eicosatrienoic acid) to trioxlin B3 (10,11,12- ... Since the hepoxilins are metabolites of arachidonic acid, hepoxilin-epoxide hydrolase participates in arachidonic acid ... eicosatrienoic acid, i.e. hepoxilin A3 and H2O, whereas its product is 8,11,12-trihydroxy-(5Z,9E,14Z)-eicosatrienoic acid, i.e ... eicosatrienoic acid. Soluble epoxide hydrolase (i.e. epoxide hydrolase 2 or EH2) sEH also appears to be the hepoxilin hydrolase ...
CAS Registry Number 1783-84-2. Eicosatrienoic acid (eicosatrienoic's, eicosatrienoic acid) has 20 carbons and is an 11,14,17- ... List of saturated fatty acids Carboxylic acid List of carboxylic acids Dicarboxylic acid Simopoulos, Artemis P. (2002). "Omega‐ ... Cervonic acid (or docosahexaenoic acid) has 22 carbons, is found in fish oil, is a 4,7,10,13,16,19-hexa unsaturated fatty acid ... β-eleostearic acid (beta-eleostearic's, beta-eleostearic acid) is a geometric isomer of α- eleostearic acid. IUPAC organization ...
12E-eicosatrienoic acid (i.e. 14,15-HxA3) and 13S/R)-hydroxy-14S,15S-epoxy-5Z,8Z,11Z-eicosatrienoic acid (i.e. 14,15-HxB3): ... those derived from the 22-carbon polyunsaturated fatty acid, docosahexaenoic acid, and the 18-carbon fatty acid, linoleic acid ... 5Z,8Z,11Z,14Z-eicosatetraenoic acid + O2 → 12S-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid → 8R/S-hydroxy-11,12-oxido-5Z,9E ... Finally, hepoxilin-like products of two other PUFAs, docosahexaenoic acid and linoleic acid, have been described. All of these ...
14Z-eicosatrienoic acid) to 15S-hydroperoxy-8Z,11Z,13E-eicosatrienoic acid and 15S-hydroxy-8Z,11Z,13E-eicosatrienoic acid (15S- ... gamma-linolenic acid, arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid when presented not only as free acids ... By metabolizing the ω-3 polyunsaturated fatty acids, eicosapentaenoic acid and docosahexaenoic acid, into 17-HpDHA, 17-HDHA, ... By metabolizing ω-3 polyunsaturated fatty acids, eicosapentaenoic acid and docosahexaenoic acid, into lipoxins and resolvins, ...
13-eicosatrienoic acid and prostaglandin E1. This is noteworthy because these compounds possess both anti-inflammatory and ... Arachidonic acid (AA) is a 20-carbon ω-6 essential fatty acid. It sits at the head of the "arachidonic acid cascade" that ... Essential fatty acid Omega-3 fatty acid Omega-6 fatty acid Ratios of Omega 3 to Omega 6 in different foods Eicosanoid ... In the arachidonic acid cascade, dietary linoleic acid (18:2 ω-6) is desaturated and elongated to form arachidonic acid (and ...
In particular, CYP2C9 metabolizes arachidonic acid to the following eicosatrienoic acid epoxide (EETs) stereoisomer sets: 5R,6S ... It likewise metabolizes docosahexaenoic acid to epoxydocosapentaenoic acids (EDPs; primarily 19,20-epoxy-eicosapentaenoic acid ... vernolic acid (also termed leukotoxin) and coronaric acid (also termed isoleukotoxin); these linoleic acid epoxides cause ... see 20-Hydroxyeicosatetraenoic acid, epoxyeicosatetraenoic acid, and epoxydocosapentaenoic acid sections on activities and ...
... hydroxy-eicosapentaenoic acid, 5(S)-hydroxy-eicosatrienoic acid, 5(S)-hydroxy-eicosadeinoic acid, 5(S)-hydroxy-eicosamonoenoic ... the 5-hydroxy fatty acids which they make or are presented with to 5-oxo fatty acids and rapidly reduce the 5-oxo fatty acids ... acid, 5(S)-hydroxy-octadecadienoic acid, 5(S),15(S)-dihydroxyeicosatetraenoic acid, and the 6-trans isomer of leukotriene B4 ( ... 14Z-eicosatetraenoic acid (i.e. 5-(S)-HETE; see 5-HETE) to its 5-keto analog, 5-oxo-eicosatetraenoic acid (i.e. 5-oxo-6S,8Z,11Z ...
11Z-eicosatrienoic acid (a 5-LO metabolite of mead acid); 5(S)-hydroxy-6E,8Z-octadecadienoic acid and 5(S)-oxo-6E,8Z- ... octadecadienoic acid (5-LO metabolites of sebaleic acid, i.e. 5Z,8Z-octadecadienoic acid); and 5(S)-hydroxy-6E,8Z,11Z,14Z,17Z- ... Eicosanoid receptor 5-Hydroxyicosatetraenoic acid and 5-oxo-eicosatetraenoic acid Niacin receptor 1 GRCh38: Ensembl release 89 ... principal receptor for the 5-Hydroxyicosatetraenoic acid family of carboxy fatty acid metabolites derived from arachidonic acid ...
Human cells synthesize LxA4 and LxB4 by serially metabolizing arachidonic acid (5Z,8Z,11Z,14Z-eicosatrienoic acid) with a) ... 16Z-docosapentaenoic acid or osbond acid) is an isomer of n-3 DPA (clupanodonic acid) differing form the latter fatty acid only ... SPM are metabolites of arachidonic acid (AA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), or n-3 DPA (i.e. 7,10Z, ... 16Z-docosapentaenoic acid, also termed osbond acid. Cells metabolize EPA (5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid) by a ...
14Z-eicosatrienoic acid): 12S-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid → 8R/S-hydroxy-11,12-oxido-5Z,9E,14Z- ... It metabolizes the omega-3 fatty acid, docosahexaenoic acid (DHA i.e., 4(Z),7(Z),10(Z),13(Z),16(Z),19(Z)-docosahexaenoic acid ... eicosatrienoic acid + 10R/S-hydroxy-11,12-oxido-5Z,8Z,14Z-eicosatrienoic acid Hepoxilins can promote certain inflammation ... 14Z-eicosatetraenoic acid) and O2 (i.e. oxygen) and its product is 12S-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid (i.e. ...
14Z-eicosatrienoic acids). However, this activity has not been characterized at the purified protein or gene level and recent ... However, sEH also metabolizes the epoxides of linoleic acid viz., Vernolic acid (leukotoxins) and Coronaric acids ( ... mEH also metabolizes certain epoxides of polyunsaturated fatty acids such as the epoxyeicosatrienoic acids (EETs) but its ... 14Z-eicosatrienoic acid) are metabolized to trioxilin A3s (8,11,12-trihydroxy-5Z,9E,14Z-eicosatrienoic acids) and hepoxilins ...
12E-eicosatrienoic acid and 13R-hydroxy-14S,15S-epoxy-5Z,8Z,11Z-eicosatrienoic acid ALOX15 appears capable of conducting both ... those derived from the 22-carbon polyunsaturated fatty acid, docosahexaenoic acid, and the 18-carbon fatty acid, linoleic acid ... 14Z-eicosatrienoic acid). This two-step metabolic reaction is illustrated below: 5Z,8Z,11Z,14Z-eicosatetraenoic acid + O2 → 12S ... 14Z-eicosatrienoic acid (trioxilin B3 or TrXB3). A third trihydroxy acid, 8,9,12-trihydroxy-5Z,10E,14Z eicosatrienoic acid ( ...
5S-hydroperoxy-eicosatetraenoic acid>5-Hydroxyeicosatetraenoic acid; the 5-oxo-eicosatrienoic and 5-oxo-octadecadienoic acid ... 12-Hydroxyeicosatetraenoic acid (S isomer)= 12-hydroperoxyeicosatetraenoic acid (S isomer)>15-Hydroxyeicosatetraenoic acid (S ... and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid". Biochimica et Biophysica Acta (BBA) - Molecular and ... BLT2 (Leukotriene B4 receptor 2) - LTB4R2; the receptor for 12-Hydroxyheptadecatrienoic acid, leukotriene B4, and certain other ...
14Z-eicosatrienoic acid) and HxB3 (i.e. 10R/S-hydroxy-11,12-oxido-5Z,8Z,14Z-eicosatrienoic acid) likewise activate TRPV1 and ... 14Z-eicosatetraenoic acid (see 20-Hydroxyeicosatetraenoic acid) and 12(S)-hydroperoxy-5Z,8Z,10E,12S,14Z-eicosatetraenoic acid ( ... are metabolites of the omega 3 fatty acids, eicosapentaenoic acid (for RvE1) or docosahexaenoic acid (for RvD2, NPD1, and Mar1 ... The metabolites of linoleic acid, including 13(S)-hydroxy-9Z,11E-octadecadienoic acid (13(S)-HODE), 13(R)-hydroxy-9Z,11E- ...
The epoxide, 5,6-epoxy-8Z,11Z,14Z-eicosatrienoic acid (5,6-EET) made by the metabolism of arachidonic acid by any one of ... Resolvin D1 (RvD1) and RvD2 (see resolvins) and maresin 1 are metabolites of the omega 3 fatty acid, docosahexaenoic acid. They ... 14Z-eicosatrienoic acid) and HxB3 (i.e. 10R/S-hydroxy-11,12-oxido-5Z,8Z,14Z-eicosatrienoic acid) (see Hepoxilin#Pain perception ... 14Z-eicosatetraenoic acid (i.e. 12S-HpETE; see 12-Hydroxyeicosatetraenoic acid) and the hepoxilins (Hx), HxA3 (i.e. 8R/S- ...
The protein FFA1 is activated by medium to long chain fatty acids. FFA1 is most strongly activated by eicosatrienoic acid (20:3 ... DHA makes up 30% and arachidonic acid, another fatty acid found in the brain, makes up 20% of the fatty acids in the brain. ... linoleic acid and oleic acid), as well as decreased neuronal response to fatty acids administered orally. GPR40 was discovered ... It has been found that certain fatty acids that are in abundance in the brain may be linked with FFA1. These fatty acids likely ...
13E-eicosatetraenoic acid 15-epi-LxB4: 5S,14R,15R-trihydroxy-6E,8Z,10E,12E-eicosatrienoic acid Note that the two LXs have their ... Lipoxins are derived enzymatically from arachidonic acid, an ω-6 fatty acid. Structurally, they are defined as arachidonic acid ... which are metabolites of the omega 3 fatty acids, eicosapentaenoic acid or docosahexaenoic acid, as well as a range of ... 13E-eicosatetraenoic acid LxB4: 5S,14R,15S-trihydroxy-6E,8Z,10E,12E-eicosatetraenoic acid 15-epi-LxA4: 5S,6R,15R-trihydroxy-7E, ...
14Z-eicosatrienoic acid (12(R)-HETrE) and to a lesser extent 12(S)-hydroxy-5Z,8Z,14Z-eicosatrienoic acid (12(S)-HETrE). The G ... 12-Hydroxyeicosatetraenoic acid (12-HETE) is a derivative of the 20 carbon polyunsaturated fatty acid, arachidonic acid, ... 14Z-eicosatrienoic acid] refer to a mixture of Diastereomers and⁄or Enantiomers derived from arachidonic acid.) Cultured RINm5F ... 12-oxo-ETE is metabolised by cytosolic NADH-dependent 12-oxoeicosinoid Δ10-reductase to 12-oxo-5Z,8Z,14Z-eicosatrienoic acid ( ...
ALOX5 metabolizes the omega-6 fatty acid, Arachidonic acid (AA, i.e. 5Z,8Z,11Z,15Z-eicosatrienoic acid), to 5- ... ALOX5 metabolizes the omega-3 fatty acid, Eicosapentaenoic acid (EPA, i.e. 4Z,8Z,11Z,14Z,17Z-eiosapentaenoic acid), to 5- ... Mead acid (i.e. 5Z,8Z,11Z-eicosatrienoic acid) is identical to AA except that has a single rather than double bond between its ... ALOX5 acts in series with ALOX15 to metabolize the omega 3 fatty acid, docosahexaenoic acid (DHA, i.e. 4Z,7Z,10Z,13Z,16Z,19Z- ...
Esculentic acid: CFN99059, Gallic acid: CFN99624, Salvianolic acid A: CFN99161, Actinidic acid: CFN98444, Pimaric acid: ... Gentisic acid (2-(2,5-dihydroxyphenyl)acetic acid) (Figure 1) is a quinonoid phenolic acid synthesized in plants. Genstisic ... Salicylic acid and gentisic acid induce RNA silencing-related genes and plant resistance to RNA pathogens. Plant Physiol ... CFN99382, Corosolic acid: CFN98685, Caffeic acid: CFN99190, Loganic acid: CFN98212). Compounds were dissolved in dimethyl ...
EETS are epoxide eicosatrienoic acid metabolites of arachidonic acid (a straight chain Eicosatetraenoic acid, omega-6 fatty ... 14Z-eicosatetraenoic acid. Cytochrome P450 epoxygenases attack these double bonds to form their respective eicosatrienoic acid ... 14Z-eicosatrienoic acid), 8,9-EET (i.e. 8,9-epoxy-5Z,11Z,14Z-eicosatrienoic acid), 11,12-EET (i.e. 11,12-epoxy-5Z,8Z,14Z- ... eicosatrienoic acid), or, as drawn in the attached figure, 14,15-EET (i.e. 14,15-epoxy-5Z,8Z,11Z-eicosatrienoic acid). The ...
오메가-6 지방산(영어: omega-6 fatty acid) 또는 ω−6 지방산(영어: ω−6 fatty acid) 또는 n−6 지방산(영어: n−6 fatty acid)은 공통적으로 n-6 위치에 탄소-탄소 이중 결합을 갖는 ... 그리고 세포 손상이 복구된 후, 염증의 해결 단계 동안 항염증성 분자(예: 리폭신 및 프로스타사이클린)의 생성으로 결국 이어진다.[4][5][6][7][8][9][10][11][12][13][14][15] ... 2007). "Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived ... "Effect of feeding systems on omega-3 fatty acids, conjugated linoleic acid and trans fatty acids in Australian beef cuts: ...
We used the patch-clamp technique to study the effect of arachidonic acid (AA) on epithelial Na channels (ENaC) in the rat ... 17-eicosatrienoic acid (EA), an unsaturated fatty acid. We followed the protocol of AA experiments and examined the ENaC ... eicosatrienoic acid; EET, epoxyeicosatrienoic acid; ENaC, epithelial Na channel; ETYA, 5,8,11,14-eicosatetraynoic acid; 20-HETE ... eicosatrienoic acid; EET, epoxyeicosatrienoic acid; ENaC, epithelial Na channel; ETYA, 5,8,11,14-eicosatetraynoic acid; 20-HETE ...
keywords = "Dihomogamma linolenic acid, Fatty acid desaturase, Global assessment of function, Neuroticism, Omega-3 fatty acids ... the predominant focus of this research has been on the n-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid ( ... the predominant focus of this research has been on the n-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid ( ... the predominant focus of this research has been on the n-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid ( ...
Arachidonic acid is metabolized to epoxyeicosatrienoic acids (EETs) by cytochrome P450 epoxygenase. Four EET regioisomers, 5,6 ... N2 - Arachidonic acid is metabolized to epoxyeicosatrienoic acids (EETs) by cytochrome P450 epoxygenase. Four EET regioisomers ... AB - Arachidonic acid is metabolized to epoxyeicosatrienoic acids (EETs) by cytochrome P450 epoxygenase. Four EET regioisomers ... abstract = "Arachidonic acid is metabolized to epoxyeicosatrienoic acids (EETs) by cytochrome P450 epoxygenase. Four EET ...
On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit liver microsomes. Fujita, V. S., Black, S. D., Tarr, G. E. ... Identification of rabbit cytochromes P450 2C1 and 2C2 as arachidonic acid epoxygenases. Laethem, R. M. & Koop, D. R., 1992, In ... P-450-dependent arachidonic acid metabolism in rabbit olfactory microsomes. Laethem, R. M., Laethem, C. L., Ding, X. & Koop, D ... Pharmacokinetic study of acid in multiple sclerosis: Comparing mice and human pharmacokinetic parameters. Yadav, V., Marracci, ...
... trioxilin C3 acid was isolated and identified as a novel biologically active arachidonic acid metabolite formed by rabbit aorta ... trioxilin C3 acid was isolated and identified as a novel biologically active arachidonic acid metabolite formed by rabbit aorta ... trioxilin C3 acid was isolated and identified as a novel biologically active arachidonic acid metabolite formed by rabbit aorta ... trioxilin C3 acid was isolated and identified as a novel biologically active arachidonic acid metabolite formed by rabbit aorta ...
12E-eicosatrienoic acid (i.e. 14,15-HxA3) and 13S/R)-hydroxy-14S,15S-epoxy-5Z,8Z,11Z-eicosatrienoic acid (i.e. 14,15-HxB3): ... those derived from the 22-carbon polyunsaturated fatty acid, docosahexaenoic acid, and the 18-carbon fatty acid, linoleic acid ... 5Z,8Z,11Z,14Z-eicosatetraenoic acid + O2 → 12S-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid → 8R/S-hydroxy-11,12-oxido-5Z,9E ... Finally, hepoxilin-like products of two other PUFAs, docosahexaenoic acid and linoleic acid, have been described. All of these ...
Cytochrome P450 (CYP) epoxygenases and their arachidonic acid (AA) metabolites, the epoxyeicosatrienoic acids (EETs), have been ... N2 - Cytochrome P450 (CYP) epoxygenases and their arachidonic acid (AA) metabolites, the epoxyeicosatrienoic acids (EETs), have ... AB - Cytochrome P450 (CYP) epoxygenases and their arachidonic acid (AA) metabolites, the epoxyeicosatrienoic acids (EETs), have ... abstract = "Cytochrome P450 (CYP) epoxygenases and their arachidonic acid (AA) metabolites, the epoxyeicosatrienoic acids (EETs ...
In this concept cloud, the sizes of the concepts are based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the same topic. The largest concepts are those that are most unique to this person ...
... eicosatrienoic acid Methyl ester is a product in category FAME with Epoxy. Buy online from Larodan Research Grade Lipids ... Hydroxy-14(S),15(S)-epoxy-5(Z),8(Z),11(Z)-eicosatrienoate, also known as 13(R)-Hydroxy-14(S),15(S)-epoxy-5(Z),8(Z),11(Z)- ... Products , Fatty Acid Methyl Esters (FAME) , FAME with Epoxy , Methyl 13(R)-Hydroxy-14(S),15(S)-epoxy-5(Z),8(Z),11(Z)- ... Methyl 13(R)-Hydroxy-14(S),15(S)-epoxy-5(Z),8(Z),11(Z)-eicosatrienoate - 100 ug. 300.00 €. ...
Other Agents. Other AA metabolites (e.g., isoprostanes, epoxy-eicosatrienoic acids, hepoxilins) have potent biological ... Lipoxygenase pathways of arachidonic acid metabolism. 5-LOX-activating protein (FLAP) presents arachidonic acid to 5-LOX, ... 17-eicosapentaenoic acid (EPA). In humans, AA, the most abundant precursor, is either derived from dietary linoleic acid (9,12- ... is a mixture of fatty acids but is enriched in arachidonic acid that may be metabolized to eicosanoids. CoA, coenzyme A. ...
On the other hand, L-ascorbic acid 2-phosphate magnesium and L-ascorbic acid 2-sulfate dipotassium salt, which do not produce ... Sodium-L-ascorbate, L-ascorbic acid, D-isoascorbic acid, sodium 5,6-benzylidene-L-ascorbate and sodium-6-beta-O-galactosyl-L- ... The rest was used for the quantification of the antioxidants ascorbic acid, uric acid, glutathione and cysteine by high ... Uric acid (micrograms/g fresh tissue) was significantly increased in neoplastic compared with non-neoplastic tissue, and levels ...
Arachidonic Acid, Bacterial Proteins, Chromatography, High Pressure Liquid, Cytochrome P-450 Enzyme System, Fatty Acids, ... The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3.. Capdevila JH, Wei S, Helvig C, ... Pentetic Acid, Rats, Rats, Sprague-Dawley, Spectrophotometry, Atomic. Added December 10, 2013 ... Unsaturated, Hydroxyeicosatetraenoic Acids, Mass Spectrometry, Mixed Function Oxygenases, Models, Molecular, NADP, NADPH- ...
... acid + [acyl-carrier_protein] + H+ 3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase - ...
triacylglycerol + H2O <=> diacylglycerol + fatty_acid + H+ 3.1.1.3 triacylglycerol lipase 3.1.1.34 lipoprotein lipase - - M ... CTP + diacylglycerol <=> CDP + phosphatidic_acid + H+ 2.7.1.174 diacylglycerol kinase (CTP) - MK ... diacylglycerol + H2O <=> monoacylglycerol + fatty_acid + H+ 3.1.1 3.1.1. 3.1.1.3 triacylglycerol lipase 3.1.1.79 hormone- ... diacylglycerol + H2O <=> sn-2-monoacylglycerol + fatty_acid + H+ 3.1.1.3 triacylglycerol lipase 3.1.1.34 lipoprotein lipase 3.1 ...
How To Pronounce Cis,cis,cis-9,12,15-octadecatrienoic acid. *How To Pronounce cis,cis,cis-9,12,15-octadecatriensyre ... How To Pronounce cis,cis,cis,cis-5,8,11,14-eikozāntetraēnskābe ... How To Pronounce Cis,cis-Muconic acid. *How To Pronounce cis, ...
Camelina has a seed yield of up to 2380 kg·ha−1 and contains around 45% fatty acids. Selection of a suitable site is critical ... and eicosatrienoic acids are also found [6,7]. Camelina oil has characteristics that distinguish it from other vegetable oils; ... Of these fatty acids, the main fatty acids are linolenic (27.9%-39.7%), linoleic (13.5%-18.7%), oleic (14.2%-17.5%) and gondoic ... above all, it has high α-linolenic acid content, which is an essential fatty acid and is added to foods [8]. However, camelina ...
Homo-γ-linolenic acid), N-Hexadecanoic acid (synonym: Palmitic acid) and Tridecanoic acid (synonym: Tridecylic acid) were the ... Palmitic acid is reported to possess antibacterial and cholesterolaemic effects27. In addition, palmitic acid and linoleic acid ... Acid values of oil samples on storage: Acid values of treated and untreated oil samples on accelerated storage are presented in ... Determination of acid value: The acid value were determined according to the AOAC19 official method using 0.5 N potassium ...
... mead acid is one marker of essential fatty acid deficiency (36). A plasma eicosatrienoic acid:arachidonic acid (triene:tetraene ... Wei J, Hou R, Xi Y, et al. The association and dose-response relationship between dietary intake of alpha-linolenic acid and ... Linoleic acid (LA), an omega-6 fatty acid, and α-linolenic acid (ALA), an omega-3 fatty acid, are considered essential fatty ... Humans can synthesize arachidonic acid (AA) from linoleic acid (LA) and eicosapentaenoic acid (EPA) and docosapentaenoic acid ( ...
... palmitoleic acid, n-9 eicosatrienoic acid, and dihomogammalinoleic acid in serum cholesterol esters (21), or total fatty acids ... FA, fatty acid; SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid; D9D, δ-9 ... Hyp, hypertension; AA, arachidonic acid; ALA, α-linolenic acid; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; BMI, ... Tsukamoto I and Tsukamoto I: Low levels of linoleic acid and α-linolenic acid and high levels of arachidonic acid in plasma ...
... fatty acid composition, and more for Dark Chocolate ... Essential Amino Acids. Essential amino acids are critical for ... Limiting Amino Acid: *Some foods that are a good source of include . ...
Dihomo-gamma-Linolenic Acid (20:3 n-6) (Polyunsaturated Fats). *Epoxyeicosatrienoic Acid, EET (20:3 n-3) (Polyunsaturated Fats) ... Linoelaidic Acid (18:2 t,t) (Polyunsaturated Fats). Also, when compared to all foods, it ranks quite high (Top 100) for 15 ... cis-Erucic Acid (22:1 c) (Monounsaturated Fats). Nutrient content compared to foods in the same category. A comparison between ... Eicosadienoic Acid (20:2 n-6 c,c) (Polyunsaturated Fats). Additionally, a comparison to foods in the same category shows that ...
... fatty acid composition, and more for Grain-Free Granola ... Essential Amino Acids. Essential amino acids are critical for ... CITRIC ACID, ASCORBIC ACID), ORGANIC COCONUT FLAKES, CASHEW BUTTER, ORGANIC RAW VIRGIN COCONUT OIL, ORGANIC CHIA SEEDS, ORGANIC ... Limiting Amino Acid: *Some foods that are a good source of include . ...
12-octadecenoic acid 12-octadecenoic acid, (cis)-isomer 12-octadecenoic acid, (trans)-isomer 12-octadecenoic acid, sodium salt ... 12-oxophytodienoic acid 12-PDDA 12-R-HETE 12-S-HETE 12-S-Hydroxyeicosatetraenoic Acid 12-sulfodehydroabietic acid 12- ... 12-oxo-10(E)-dodecenoic acid 12-oxo-cis-10, cis-15-phytodienoic acid 12-oxo-PDA 12-oxo-phytodienoic acid 12-oxophytodienoate ... 12-hydroxy-9-octadecenic acid 12-hydroxy-9-octadecenoic acid 12-hydroxy-ibogamine 12-hydroxyeicosatetraenoic acid receptor 12- ...
Eicosatrienoic Acid. ~. 20:3 n-3. ~. Dihomo-gamma-linolenic acid. ~. Arachidonic Acid. 0.0 mg. ...
Dihomo-gamma-Linolenic Acid (20:3 n-6) (Polyunsaturated Fats). *Eicosatrienoic Acid (20:3) (Polyunsaturated Fats) ... Brassidic Acid (22:1 t) (Monounsaturated Fats). Also, when compared to all foods, it ranks quite high (Top 100) for 10 ... Dihomo-gamma-Linolenic Acid (20:3 n-6) (Polyunsaturated Fats). Nutrient content compared to foods in the same category. A ... Secondly youll find a lipid (fat) profile that shows you the content of saturated, mono-, and polyunsaturated fatty acids. ...
  • However, the predominant focus of this research has been on the n-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). (elsevier.com)
  • A second group of less well studied hepoxilins, HxA4 , HxB4 , and their non-enzymatically formed isomers are nonclassical eicosanoids derived from the PUFA, eicosapentaenoic acid . (wikipedia.org)
  • The long-chain omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), can be synthesized from ALA, but due to low conversion efficiency, it is recommended to consume foods rich in EPA and DHA. (oregonstate.edu)
  • Gas chromatography (GC) analysis of F. oxysporum NRC 2017 biodiesel showed the presence of 2.2% palmitoleic acid, 11.1% oleic acid, 5.6% linoleic acid, 3.0% α-linoleic acid, 2.5% eicosatrienoic acid, 6.8% eicosapentaenoic acid, 16.1% erucic acid, 4.2% margaric acid, and 3.9% behenic acid. (springeropen.com)
  • During microbial insult or cellular injuries, arachidonic acids and other related polyunsaturated fatty acids, like eicosapentaenoic acids (EPA) and docosahexaenoic acids (DHA), are metabolized via three major metabolic pathways, Cyclooxygenase (COX), Lipoxygenase (COX), and CYP450, to produce hundreds of lipid species with diverse physiological activities. (frontiersin.org)
  • and HAM-D to negatively correlate with linoleic acid (LA) and positively correlate with fatty acid desaturase 2 (FADS2) activity, an enzyme responsible for converting LA to gamma-linolenic acid (GLA). (elsevier.com)
  • Finally, hepoxilin-like products of two other PUFAs, docosahexaenoic acid and linoleic acid , have been described. (wikipedia.org)
  • [3] [4] A hepoxilin-like derivative of linoleic acid is formed on linoleic acid that is esterified to a sphingosine in a complex lipid termed esterified omega-hydroxylacyl-sphingosin (EOS). (wikipedia.org)
  • Linoleic acid (LA), an omega-6 fatty acid , and α-linolenic acid (ALA), an omega-3 fatty acid, are considered essential fatty acids because they cannot be synthesized by humans. (oregonstate.edu)
  • The plasma level of linoleic acid (LA) in the subjects with hypertension (systolic BP ≥140 mmHg and/or diastolic BP ≥90 mmHg) was identified to be significantly higher than that in the healthy controls. (spandidos-publications.com)
  • A summary of the International Study of Macro/Micronutrients and Blood Pressure (INTERMAP) reported that total PUFA, linoleic acid (LA), total n-3 FA, and α-linolenic acid (ALA), were inversely associated with BP ( 10 ). (spandidos-publications.com)
  • Essential amino acids are critical for building protein. (prospre.io)
  • Fish protein powder is a highly absorbable source of predigested protein offering supreme palatability and a full spectrum of amino acids for proper growth, development, and maintenance. (modernk9.ca)
  • Protease (dried Bacillus subtilis fermentation product) is a digestive enzyme that breaks down peptide bonds found in proteins into the building blocks of amino acids, which can then be easily absorbed by the body through the intestinal walls. (modernk9.ca)
  • Sitagliptin significantly decreased polyunsaturated fatty acids, especially ω6 fatty acids, whereas voglibose altered serum levels of many kinds of fatty acids. (bmj.com)
  • 100% vs. 43% for compound A and 5% vs. 100% for compound B). Based on the mass spectra, peak 3 contained two metabolites identified as the methyl ester-trimethylsilyl ether derivatives of 8,11,12-trihydroxyeicosatrienoic acid (trioxilin A 3 ) and 8,9,12-trihydroxyeicosatrienoic acid (trioxilin C 3 ). (elsevier.com)
  • In all omega-6 (ω6 or n-6) fatty acids, the first double bond is located between the sixth and seventh carbon atom from the methyl end of the fatty acid. (oregonstate.edu)
  • Likewise, all omega-3 fatty acids (ω3 or n-3) have at least one double bond between the third and fourth carbon atom counting from the methyl end of the fatty acid. (oregonstate.edu)
  • Although humans and other mammals can synthesize saturated fatty acids and some monounsaturated fatty acids from carbon groups in carbohydrates and proteins , they lack the delta (Δ) 12 and Δ15 desaturase enzymes necessary to insert a cis double bond at the n-6 or the n-3 position of a fatty acid (1) . (oregonstate.edu)
  • The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of arachidonic acid by a specific subset of Cytochrome P450 enzymes termed cytochrome P450 epoxygenases. (wikipedia.org)
  • Determination of the role of the EETS in human diseases is made particularly difficult because of the large number of EET-forming epoxygenases, large number of epoxygenase substrates other than arachidonic acid, and the large number of activities, some of which may be pathological or injurious, that the EETs possess. (wikipedia.org)
  • EETS are epoxide eicosatrienoic acid metabolites of arachidonic acid (a straight chain Eicosatetraenoic acid, omega-6 fatty acid). (wikipedia.org)
  • The CYP epoxygenases can epoxidize any of the double bounds in arachidonic acid but most of them are relatively selective in that they make appreciable amounts of only one or two EETs with 11,12-EET and 14,15-EET accounting for 67-80% of the product made by the cited CYP epoxidases as well as the main EETs made by mammalian tissues. (wikipedia.org)
  • Arachidonic acid is metabolized to epoxyeicosatrienoic acids (EETs) by cytochrome P450 epoxygenase. (utmb.edu)
  • Cytochrome P450 (CYP) epoxygenases and their arachidonic acid (AA) metabolites, the epoxyeicosatrienoic acids (EETs), have been shown to produce reductions in infarct size in canine myocardium following ischemia-reperfusion injury via opening of either the sarcolemmal K ATP (sarcK ATP ) or mitochondrial K ATP (mitoK ATP ) channel. (elsevier.com)
  • Both dietary intake and endogenous metabolism influence whole body status of essential fatty acids. (oregonstate.edu)
  • To enjoy robust health, your cat should receive a high quality vitamin/mineral supplement, alongside essential fatty acids, digestive enzymes, and other nutrients. (modernk9.ca)
  • Lipase (dried Aspergillus oryzae fermentation product) is a digestive enzyme needed to help break down fats and form essential fatty acids needed to ensure viable cells. (modernk9.ca)
  • The notion that the inhibitory effect of AA is mediated by CYP-epoxygenase-dependent metabolites is also supported by the observation that application of 200 nM 11,12-epoxyeicosatrienoic acid (EET) inhibited ENaC in the CCD. (rupress.org)
  • Reduced levels of LA and P/S ratio, and elevated levels of palmitic acid and arachidonic acids (AA) in plasma cholesterol esters were associated with a higher risk of hypertension ( 23 ). (spandidos-publications.com)
  • Hepoxilins (Hx) are a set of epoxyalcohol metabolites of polyunsaturated fatty acids (PUFA), i.e. they possess both an epoxide and an alcohol (i.e. hydroxyl ) residue. (wikipedia.org)
  • HxA3 , HxB3 , and their non-enzymatically formed isomers are nonclassic eicosanoid derived from acid the (PUFA), arachidonic acid . (wikipedia.org)
  • Omega-6 and omega-3 fatty acids are polyunsaturated fatty acids (PUFA), meaning they contain more than one cis double bond (1) . (oregonstate.edu)
  • Animal studies have demonstrated that diets high in saturated fatty acid (SFA) increase BP ( 2 , 3 ), whereas diets enriched with n-3 polyunsaturated fatty acid (PUFA) protect against BP elevation ( 4 - 6 ). (spandidos-publications.com)
  • No significant correlations have been observed between hypertension and intakes of SFA and PUFA ( 7 , 8 ). (spandidos-publications.com)
  • Data from meta-analyses ( 11 , 12 ) and clinical trials ( 13 , 14 ) have indicated that n-3 PUFA supplementation dose-dependently reduces BP in hypertensive patients, but not in normotensive individuals. (spandidos-publications.com)
  • The serum/plasma levels of PUFA were significantly correlated with the intake of polyunsaturated fat ( 16 ), while its levels of 14:0, 16:0, 18:0, and monounsaturated FA may reflect a diet rich in saturated fat, due to their high correlations with saturated fat ( 19 ). (spandidos-publications.com)
  • Hypertensive men had lower C22:6/C20:5 [n-3 δ-6 desaturase (D6D) index], PUFA and polyunsaturated/saturated fatty acid (P/S) ratios in their serum free FA composition ( 24 ). (spandidos-publications.com)
  • Omega-3 (n-3) fatty acids have been implicated in mood disorders, yet clinical trials supplementing n-3 fats have shown mixed results. (elsevier.com)
  • Western blot analysis of proteins in the mitogen-activated protein (MAP) kinase signaling pathway showed that ERK1/2 phosphorylation was increased by gentisic acid treatment. (medsci.org)
  • Kelp is an excellent source of iodine and vitamin K, a very good source of B-vitamins, magnesium, iron, calcium, pantothenic acid, and a good source of lignans. (modernk9.ca)
  • only a relatively few of the active CYP genes code for EET-forming epoxygenases, i.e. protein enzymes with the capacity to attach atomic oxygen (see Allotropes of oxygen#Atomic oxygen) to the carbon-carbon double bonds of unsaturated long chain fatty acids such as arachidonic acid. (wikipedia.org)
  • Most of these lipids which were composed of long chain fatty acids were similar to conventional vegetable oils (Rude and Schirmer 2009 ). (springeropen.com)
  • Cytochrome P450 epoxygenases attack these double bonds to form their respective eicosatrienoic acid epoxide regioisomers (see Structural isomer, section on position isomerism (regioisomerism)) viz. (wikipedia.org)
  • Stearic acid, palmitoleic acid, n-9 eicosatrienoic acid, and dihomogammalinoleic acid in serum cholesterol esters ( 21 ), or total fatty acids, SFA, and LA in plasma PL were indicated to be associated with BP ( 22 ). (spandidos-publications.com)
  • Recently, 14,15-HxA3 and 14,15-HxB3 have been defined as arachidonic acid derivatives that are produced by a different metabolic pathway than HxA3, HxB3, HxA4, or HxB4 and differ from the aforementioned hepoxilins in the positions of their hydroxyl and epoxide residues. (wikipedia.org)
  • Endocannabinoids are all fatty acid derivatives. (researchgate.net)
  • the effect of sterilization on plastics and messenger, with high capture of pyridazinyl of block markers and action of organism flow oxidation Is in heart with the acid of full Cardiomyoplasty. (augenta.net)
  • Voglibose increased low-density lipoprotein-cholesterol levels and altered serum levels of several fatty acids, and increased Δ-5 desaturase activity. (bmj.com)
  • Measuring brain manganese and iron accumulation in rats following 14 weeks of low-dose manganese treatment using atomic absorption spectroscopy and magnetic resonance imaging. (vanderbilt.edu)
  • These data suggest that specific n-6 fatty acids and the enzymes that control their biosynthesis may be useful biomarkers in measurements of depressive disorders and burden of disease, and that they should be considered when investigating the roles of n-3s. (elsevier.com)
  • Genetic polymorphisms in fatty acid synthesizing enzymes can have a significant impact on fatty acid concentrations in the body. (oregonstate.edu)
  • These nonclassic eicosanoids are generally short-lived, being rapidly converted from epoxides to less active or inactive dihydroxy-eicosatrienoic acids (diHETrEs) by a widely distributed cellular enzyme, Soluble epoxide hydrolase (sEH), also termed Epoxide hydrolase 2. (wikipedia.org)
  • The 14,15-HxA3 and 14,15-HxB3 non-classical eicosanoids are distinguished from the aforementioned hepoxilins in that they are formed by a different metabolic pathway and differ in the positioning of their epoxide and hydroxyl residues. (wikipedia.org)
  • Second, the R , S versus S , R chirality of the epoxide residue in these earlier studies likewise goes undefined and given with, for example, HxB3 as 11,12-epoxide. (wikipedia.org)
  • For example, the scientific abbreviation for α-linolenic acid (ALA) is 18:3n-3. (oregonstate.edu)
  • Following adjustment for age, body mass index, physical activity, smoking status, alcohol consumption, salt intake, and serum levels of glucose and hemoglobin A1c, higher plasma levels of LA and α-linolenic acid (ALA), and lower levels of arachidonic acid (AA) were significantly associated with a lower prevalence of hypertension. (spandidos-publications.com)
  • for example, cytochrome P450 epoxidases metabolize arachidonic acid to a mixture of 14R,15S-EET and 14S,15R-EET. (wikipedia.org)
  • Moreover, inhibition of either cyclooxygenase (COX) with indomethacin or cytochrome P450 (CYP) ω-hydroxylation with N -methylsulfonyl-12,12-dibromododec-11-enamide (DDMS) failed to abolish the effect of AA on ENaC. (rupress.org)
  • Consequently, omega-6 and omega-3 fatty acids are essential nutrients. (oregonstate.edu)
  • Biodiesel is a long chain of fatty acid alkyl esters derived from renewable feedstock and it was used as a partial or full substitute for petrol diesel. (springeropen.com)
  • Thereafter, chemical properties of the oil samples including peroxide value, anisidine value, iodine value, acid value, saponification value as well as sensory evaluation was also conducted on monthly basis throughout the storage period. (scialert.net)
  • Biodiesel from F. oxysporum NRC2017 was blended with petroleum diesel in 5% "B5" and the physical properties results were density 0.84 g/ml, viscosity 2.55 mm 2 /s, cloud point 0 °C, iodine value 92.71 gI2/100 g, acid value 1.6 mg/g, and pour point − 1.3 °C. (springeropen.com)
  • First, molecular oxygen (O 2 ) is added to carbon 12 of arachidonic acid (i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid) and concurrently the 8 Z double bond in this arachidonate moves to the 9 E position to form the intermediate product, 12 S -hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid (i.e. 12 S -hydroperoxyeicosatetraenoic acid or 12 S -HpETE). (wikipedia.org)
  • We investigated the metabolism of 12-hydroperoxyeicosatetraenoic acid by aortic homogenates and microsomes. (elsevier.com)
  • Scientific abbreviations for fatty acids tell the reader something about their chemical structure. (oregonstate.edu)