Nucleotidases

5'-Nucleotidase

Apyrase

Cytidine Monophosphate

Haloferax volcanii

Pyrimidine Nucleotides

Steatitis

Anemia, Hemolytic

Uridine Monophosphate

Adenosine Monophosphate

Phosphoric Monoester Hydrolases

Adenosine Triphosphatases

Pyrophosphatases

Adenosine

Kinetics

Adenosine Diphosphate

Archaeal Proteins

Adenosine Triphosphate

Substrate Specificity

Erythrocytes

Nucleotides

Proteasome Endopeptidase Complex

Molecular Sequence Data

Microscopy, Electron

Hydrogen-Ion Concentration

Cell Membrane

Amino Acid Sequence

Molecular Weight

Electrophoresis, Polyacrylamide Gel

Liver

Mutation

Encyclopedias as Topic

Vertebrates

Phosphodiesterase I

Snake Venoms

Toxicity Tests

No-Observed-Adverse-Effect Level

Toxicity Tests, Chronic

Toxicity Tests, Acute

Legislation, Food

Functional Food

Toxicity Tests, Subchronic

Liver function tests

Inclusion body myositis

NT5C1A

NT5M

NT5E

NT5C

Herbert Zimmermann (neuroscientist)

Kuhl's maskray

NT5C3

Cholestasis

Nucleic acid metabolism

BAY 60-6583

Ornithodoros savignyi

Tubuloglomerular feedback

Alkaline phosphatase

Basophilic stippling

Lead(II) nitrate

Phosphatase

Annexin A2

Find-me signals

Laminin subunit alpha-1

Purinergic signalling

Legionella pneumophila

Nucleotide salvage

Hemolytic anemia

GUK1

Cladribine

DGUOK

SurE, survival protein E

5'-acylphosphoadenosine hydrolase

MiR-137

Evans blue (dye)

Đái Duy Ban

Carol Remmer Angle

Fluorodeoxyuridylate

SpoT

Purine metabolism

Indian cobra

5'-nucleotidase

Enzyme kinetics

Arterial calcification due to CD73 deficiency

Allosteric regulation

T-Cell Acute Lymphoblastic Leukemia

Regucalcin

List of diseases (0-9)

Chromosome 17

List of MeSH codes (D08)

CD7316

• Wolff G, Truse R, Decking U. Extracellular Adenosine Formation by Ecto-5'-Nucleotidase (CD73) Is No Essential Trigger for Early Phase Ischemic Preconditioning. (medscape.com)
• Alternative splicing of human NT5E in cirrhosis and hepatocellular carcinoma produces a negative regulator of ecto-5'-nucleotidase (CD73). (medscape.com)
• Novel, small molecule nucleotide derivatives have been developed containing either a purine or pyrimidine nucleobase that competitively block the enzyme CD73, or ecto-5'-nucleotidase. (nih.gov)
• Production of anti-inflammatory adenosine by ecto-5′-nucleotidase (CD73) helps maintain endothelial barrier function. (thelancet.com)
• CD73 (ecto-5'-nucleotidase) is a 69 kD GPI-anchored surface protein. (biolegend.com)
• CD73 is a 5'-nucleotidase anchored to the membrane by a glycosylphosphatidylinositol (GPI) structure. (beckman.com)
• In addition, CD73, a 5'-nucleotidase, can be used to release the 5'-phosphate from 5'-AMP to increase the assay sensitivity by two-fold. (rndsystems.com)
• The addition of the nucleotidase CD73 is optional. (rndsystems.com)
• Also known as ecto-5' nucleotidase or 5'-nucleotidase, CD73 is an anchored cell surface protein that plays a critical role in purinergic signaling by catalyzing the hydrolysis of AMP into adenosine and phosphate. (the-scientist.com)
• 2015). Deficits in Endogenous Adenosine Formation by Ecto-5′-Nucleotidase/CD73 Impair Neuromuscular Transmission and Immune Competence in Experimental Autoimmune Myasthenia Gravis . (up.pt)
• Prior research has focused largely on the two major ectonucleotidases, ectonucleoside triphosphate diphosphohydrolase 1/cluster of differentiation (CD)39 and ecto-5'-nucleotidase/CD73, which catalyze the breakdown of extracellular ATP into adenosine, and on the subsequent activation of different subtypes of adenosine receptors with mixed findings of antitumor and protumor effects. (utu.fi)
• Additionally, ≥ 95% of the MSCs population must positively express a cluster of differentiation superficial antigenic markers of hematopoietic differentiation called CDs (for cluster of differentiation) such as CD105 (endoglin), CD73 (ecto-5'-nuclease), and CD90 (Thy1), as measured by flow cytometry. (pocketdentistry.com)
• CD73, also known as 5′-nucleotidase (5′-NT), is commonly used to convert amp to adenosine. (immune-system-research.com)
• CD73, known as ecto-5′-nucleotidase (ecto-5′-NT, EC 3.1.3.5) is a glycosyl-phosphatidylinositol (GPI)-linked 70-kDa cell surface enzyme found in most tissues. (immune-system-research.com)
• Ecto-5'-nucleotidase as a glycosylphosphatidylinositol-anchored membrane protein which is defined as the lymphocyte differentiation antigen (CD73). (azpdf.org)
• The NT5E (CD73) molecule represents an ecto-5'-nucleotidase expressed on the cell surface of various cell types. (shengsci.com)

Adenosine17

• Holmes AP, Nunes AR, Cann MJ, Kumar P. Ecto-5'-Nucleotidase, Adenosine and Transmembrane Adenylyl Cyclase Signalling Regulate Basal Carotid Body Chemoafferent Outflow and Establish the Sensitivity to Hypercapnia. (medscape.com)
• In mammalian cells the enzyme is predominantly located in the plasma membrane and its primary role is in the conversion of extracellular nucleotides (e.g. 5'-AMP), which are generally impermeable, to the corresponding nucleoside (e.g. adenosine) which can readily enter most cells. (wikipedia.org)
• Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate. (ntu.edu.sg)
• 8,000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1.0 pmole of Adenosine 5-monophosphate to phosphate per minute per minute at pH 7.5 at 25°C. (prospecbio.com)
• In this method, Golgi-resident PAP-specific 3'-phosphatase (gPAPP) is used to release the 3'-phosphate from PAP, generating 5'-adenosine monophosphate (5'-AMP). (rndsystems.com)
• 8-Butylthio-2', 3'-isopropylidene − adenosineβ, γ -methylene 5'-triphosphate (14 ) 8-Butylthio-2′,3′-isopropylidene-adenosine (13) (100 mg, 0.25 mmol) was dissolved in dry trimethyl phosphate (1.5 mL), cooled to -15°C, and proton sponge was added (178.6 mg, 0.83 mmol, 3.3 eq). (dadospdf.com)
• Adenosine A2A Receptor Agonist, 2-p-(2-Carboxyethyl)phenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride hydrate (CGS21680), Inhibits Inflammation and Increases Fibroblast Growth Factor 2 (FGF-2) Tissue Expression in Carrageenan Induced Rat Paw Edema. (unina.it)
• Adenosine is the final product of ATP metabolism, mainly derived from the action of 5'- nucleotidase cleavage of AMP. (unina.it)
• The purpose of the present work was to investigate on the antinflammatory effect of systemic administration of the adenosine A2A agonist, 2-p-(2- Carboxyethyl)phenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride hydrate (CGS21680), in the rat model of carrageenan-induced paw edema. (unina.it)
• Results: Analgesia and increased ecto-5'-nucleotidase expression and adenosine content in the spinal cord were observed 1 h after electroacupuncture. (scielo.org)
• α,β-methyleneadenosine 5'-diphosphate was able to inhibit upregulation of adenosine content and electroacupuncture-induced analgesia. (scielo.org)
• Conclusions: Our results suggest that electroacupuncture at Zusanli can produce analgesia in chronic constriction injury rat models, possibly via the increased ecto-5'-nucleotidase expression induced through electroacupuncture, thus leading to increased adenosine expression in the spinal cord. (scielo.org)
• In addition, released ATP may be dephosphorylated by extracellular nucleotidases to form endogenous adenosine sequentially. (kw-6002.info)
• Ecto-5-nucleotidase (Ecto-5-NTase), the limiting enzyme of the ectonucleotidase pathway, plays an important role in regulating the rate of local adenosine production from adenine nucleotides. (kw-6002.info)
• The failure of ecto-5-nucleotidase inhibitors to modify [3H]ACh release during brief stimulation trains contrasts with the facilitatory effect of the exogenously added adenosine precursor AMP. (kw-6002.info)
• Alternatively, the postsynaptic localization of ecto-5-nucleotidase (Nitahara and models suggest that the balance between inhibitory adenosine A1 and facilitatory A2A receptors may be important in regulating intestinal motility. (kw-6002.info)
• Removing a phosphate group via nucleotidase to form adenosine followed by deamination (removal of a -NH2 amino group) to form inosine. (tigerfitness.com)

Cytosolic3

• 5'-nucleotidase, cytosolic II genotype, and clinical outcome in patients with acute myeloid leukemia with intermediate-risk cytogenetics. (cdc.gov)
• Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia. (cdc.gov)
• Cytosolic 5′-Nucleotidase 1A As a Target of Circulating Autoantibodies in Autoimmune Diseases" Arthritis Care & Research 68(1): 66-71 (2015). (abmgood.com)

Pyrimidine6

• Numerous studies have shown that erythrocyte pyrimidine 5′-nucleotidase activity is significantly lowered in patients with lead poisoning, and that pyrimidine 5′-nucleotidase activity can be used as an index of lead poisoning. (wikipedia.org)
• The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. (nih.gov)
• A) in NT5C3A associated with hereditary pyrimidine 5'-nucleotidase deficiency: two cases report and literature review]. (nih.gov)
• A New Homozygous Mutation (c.393-394del TA/c.393-394del TA) in the NT5C3 Gene Associated With Pyrimidine-5'-Nucleotidase Deficiency: A Case Report. (nih.gov)
• The intracellular pyrimidine 5'-nucleotidase NT5C3A is a negative epigenetic factor in interferon and cytokine signaling. (nih.gov)
• Lead also increases the rate of red blood cell destruction due to the profoundly depressed activities of erythrocyte pyrimidine 5′-nucleotidase (P5N) activities. (elsevier.com)

Protein11

• 5'-nucleotidase (5'-NT) is a protein produced by the liver. (medlineplus.gov)
• Ecto‑5'‑nucleotidase, also termed cluster of differentiation (CD)73, is a protein that is activated in several types of aggressive cancer and may promote cancer progression. (spandidos-publications.com)
• Ecto-5′-nucleotidase, also termed cluster of differentiation (CD)73, is a glycosyl phosphatidylinositol-linked membrane protein found on the surface of a variety of cell types ( 14 ). (spandidos-publications.com)
• Significant sequence homology between the E. coli 5'-nucleotidase and members of the Ser/Thr protein phosphatase family in the catalytic site has lead to 5'-nucleotidase being included in this protein family. (edu.au)
• The molecular weight of the mature protein was estimated as 58219 daltons, with a specific activity for 5'-AMP, in the presence of 4 mM Co2+ and 13 mM Ca2+ at pH 6.0, of 730 mmol/min/mg. (edu.au)
• Seven key catalytic site residues (Asp-41, His-43, Asp-84, His-117, Glu-118, His-217 and His-252) were selected on the basis of sequence conservation within the Ser/Thr protein phosphatases and 5'-nucleotidases. (edu.au)
• Is predicted to encode a protein with the following domain: Warthog protein 3/5. (wormbase.org)
• 5-hydroxytryptamine, ATP and Glu act through both G protein-coupled receptors (GPCRs), and ionotropic receptors, i.e., ligand gated ion channels. (frontiersin.org)
• 5-HT, Glu and ATP, taken as regulatory molecules, share being the endogenous agonists of two types of cell surface receptors: G protein-coupled receptors (GPCRs) and ionotropic receptors. (frontiersin.org)
• indicates that the protein contains two domains (at least), one of which performs the role Glutamate 5-kinase and the other which performs the role RNA-binding C-terminal domain PUA . (bv-brc.org)
• Laminin-332 (laminin-5) is a basement membrane heterotrimeric protein composed of alpha-3, beta-3 and gamma-2 laminin chains. (morulaivf.com)

Synonyms1

• Biomolecule/Target: NT5C3B Alternates names: NT5C3L, 7-methylguanosine phosphate-specific 5'-nucleotidase Synonyms: NT5C3L, 7-methylguanosine phosphate-specific. (telospub.com)

Serum3

• Serum levels of 5′-nucleotidase in disease. (medscape.com)
• Pathological jaundice in newborns should be suspected when the serum bilirubin level rises by more than 5 mg/dL per day, serum bilirubin more than the physiological range, clinical jaundice more than 2 weeks, and conjugated bilirubin (dark urine staining clothes). (wikipedia.org)
• The serum alkaline phosphatase (AP) is typically elevated four to five times the upper limit of normal, but elevations up to 20 times the pediatric upper reference limit (or 50 times the adult upper reference limit) have been described [ 5-7 ]. (houstonwehaveaproblemblog.com)

Alkaline3

• Laboratory tests for cholestasis include GGT, alkaline phosphatase, and 5′ nucleotidase, of which GGT and alkaline phosphatase are most widely used. (medscape.com)
• However, acid and alkaline phosphatase, NADH oxidase and 5′-nucleotidase showed no such specific location. (microbiologyresearch.org)
• In addition to AST and ALT, alkaline phosphatase, 5' nucleotidase, and gamma-glutamyl transpeptidase (GGT) are a few of the other enzymes located in the liver. (vaccinehealthcenter.com)

Enzyme9

• 5′-Nucleotidase (5NT) is an intrinsic membrane glycoprotein that is present as an enzyme in a wide variety of mammalian cells. (medscape.com)
• 5′-Nucleotidase (EC 3.1.3.5) is an enzyme which catalyzes the phosphorylytic cleavage of 5′-nucleotides. (wikipedia.org)
• The enzyme has a wide substrate specificity for nucleotides and has been shown to hydrolyze 5'nucleotides rapidly, ribose-5-phosphate slowly, and other phosphate esters extremely slowly (if at all). (wikipedia.org)
• Studies of mammalian 5′-nucleotidases have shown that there exist at least four different forms of the 5′-nucleotidase enzyme: one membrane-bound form and three soluble forms. (wikipedia.org)
• This is due to the fact that the enzyme activity is approximately 10-times higher for peripheral T cells than thymocytes, 5-6 times higher in adult peripheral B cells than fetal B cells, and largely absent in non-T cell and non-B cell lymphocytes. (wikipedia.org)
• MAF-treated cells were also found to lose 5′ nucleotidase activity faster than control cells in the presence of cycloheximide, suggesting such cells may have a higher membrane turnover of this enzyme. (elsevier.com)
• Escherichia coli 5'-nucleotidase is a periplasmically localised enzyme capable of hydrolysing a broad range of substrates, including all 5'-ribo- and 5'-deoxyribonucleotides, uridine diphosphate sugars, and a number of synthetic substrates such as bis (r-nitrophenyl) phosphate. (edu.au)
• This thesis describes the development of a rapid purification methodology for milligram quantities of 5'-nucleotidase, and the investigation of a number of physical and biochemical properties of the enzyme with the aim of comparing these properties to those of certain catalytic site mutants. (edu.au)
• Three plasma membrane-located enzyme activities were analysed: Mg2+-dependent ATPase, 5´-nucleotidase and adenylyl cyclase. (lu.se)

Nucleoside4

• This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. (nih.gov)
• Lymphocyte activity of purine nucleoside phosphorylase and 5'-nucleotidase (5NT) and erythrocyte activity of TPMT, key enzymes in thiopurine catabolism, were measured in 3 RA patients who had experienced AZA-related bone marrow toxicity and in 16 RA patients without signs of toxicity despite at least 6 months of treatment with AZA. (nih.gov)
• Nucleoside kinases catalyse the reverse reaction to 5-nucleotidase, and these reverse reactions have been suggested for almost all the nucleotideCnucleoside pairs [11]. (lde225.info)
• mRNAs were amplified and applied to a Focused DNA Array, which was restricted to well-known genes, including GEM sensitivity-related genes, deoxycytidine kinase (dCK), human equilibrative nucleoside transporter 1 (hENT1), hENT2, dCMP deaminase, cytidine deaminase, 5'-nucleotidase, ribonucleotide reductase 1 (RRM1) and RRM2. (fujita-hu.ac.jp)

Ecto13

• The role of ecto-5'-nucleotidase in endothelial dysfunction and vascular pathologies. (medscape.com)
• Studies of the soluble form of human ecto-5′-nucleotidase, without a GPI anchor, have shown that the C-terminal domain holds the substrate-binding pocket, and that the aromatic purine motif of the substrate is stacked between two phenylalanine residues. (wikipedia.org)
• The test may also be referred to as 5'NT Levels Blood Test, CDF73 Levels Blood Test, and Ecto-5'-Nucleotidase Levels Blood Test. (wikipedia.org)
• Physiopathological role of ecto-5`-nucleotidase - a new target for neuroprotection. (fct.pt)
• Objective: This study aimed to determine the role that ecto-5'-nucleotidase plays in EA-induced analgesia for neuropathic pain. (scielo.org)
• We observed the mechanical withdrawal threshold and thermal pain threshold and detected the expression of ecto-5'-nucleotidase in the spinal cord using Western blot. (scielo.org)
• Chronic constriction injury rat models were intraperitoneally injected with α,β-methyleneadenosine 5'-diphosphate, an ecto-5'-nucleotidase inhibitor, 30 min before electroacupuncture. (scielo.org)
• Objetivo: Este estudo teve como objetivo determinar o papel que a ecto-5'-nucleotidase desempenha na analgesia induzida por EA para dor neuropática. (scielo.org)
• Observamos o limiar de retirada mecânica e o limiar de dor térmica, e detectamos a expressão de ecto-5'-nucleotidase na medula espinhal usando Western blot. (scielo.org)
• Modelos de ratos com lesão de constrição crônica foram injetados intraperitonealmente com α, β-metilenadenosina 5'-difosfato, um inibidor de ecto-5'-nucleotidase, 30 min antes da eletroacupuntura. (scielo.org)
• Resultados: Analgesia e aumento da expressão de ecto-5'-nucleotidase e conteúdo de adenosina na medula espinhal foram observados 1 h após a eletroacupuntura. (scielo.org)
• Conclusões: Nossos resultados sugerem que a eletroacupuntura em Zusanli pode produzir analgesia em modelos de ratos com lesão de constrição crônica, possivelmente por meio do aumento da expressão de ecto-5'-nucleotidase induzida por eletroacupuntura, levando ao aumento da expressão de adenosina na medula espinhal. (scielo.org)
• Gustaffson induced by electrical stimulation (Begg the ecto-nucleotidase pathway activates facilitatory A2A receptors in a time-dependent manner. (kw-6002.info)

Extracellular1

• One of the soluble forms appears to be derived from the GPI-anchored ex-5'-nucleotidase and has an extracellular location. (wikipedia.org)

Monophosphate3

• Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. (nih.gov)
• Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP) (PubMed:24603684). (icr.ac.uk)
• Guanosine 3',5'-cyclic monophosphate (cyclic GMP or cGMP) is a second messenger that is biosynthesized from GTP by guanylate cyclases. (glpbio.cn)

Enzymes1

• Sulfotransferases are a large group of enzymes that transfer sulfate from the donor substrate 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to various acceptor substrates, generating 3'-phosphoadenosine-5'-phosphate (PAP) as a by-product. (rndsystems.com)

Glutamate1

• We have decided to put into perspective three examples with their analogies and differences, namely 5-hydroxytryptamine (5-HT), glutamate (Glu) and ATP. (frontiersin.org)

Dephosphorylation1

• This is then followed by dephosphorylation (removal of a phosphate group) by a nucleotidase to form inosine. (tigerfitness.com)

Source:HGNC Symbol1

• exophilin 5 [Source:HGNC Symbol;Ac. (gsea-msigdb.org)

Antibodies3

• Polyclonal and monoclonal antibodies against chicken gizzard 5 '-nucleotidase inhibit the spreading process of chicken embryonic fibroblasts on laminin substratum. (morulaivf.com)
• Polyclonal and monoclonal antibodies raised against chicken gizzard 5′-nucleotidase were tested in adhesion assays of embryonic chicken fibroblasts (CEF) for their ability to interfere with the adhesion process of these cells on either laminin or fibronectin substrata. (morulaivf.com)
• The initial attachment process of CEF on fibronectin and laminin substrata was not influenced by preincubating these cells with antibodies against chicken gizzard 5′-nucleotidase. (morulaivf.com)

20191

• av R De la Rosa · 2019 · Citerat av 3 - For cDNA synthesis, 1 µg of total RNA was digested with DNase and incubated at 37 °C for 30 min, and 1 µL of 5 mM EDTA was then added to stop reaction the first reaction, age group, gestation period when reaction/event was observed females in the last third of gestation, non-castrated bulls and bovines shipped Breed or mix between? (web.app)

Antibody1

• In vitro assays demonstrated a competition of laminin and this monoclonal antibody for the binding site on purified 5′-nucleotidase. (morulaivf.com)

Phosphodiesterase1

• relationship between the active sites of 2',3'-cyclic phosphodiesterase with 3'-nucleotidase activity purified from vibrio alginolyticus. (liverpool.ac.uk)

Gene1

• To better understand the complex family of nucleotidases in vegetation, we have cloned and characterised the gene encoding a new nucleotidase member of the HAD superfamily in sequence (Phvul.004G174200) was conducted in the NCBI database in the genome [24]. (lde225.info)

Recombinant1

• KEY RESULTS The compounds 8-BuS-AMP, 8-BuS-ADP and 8-BuS-ATP inhibit recombinant human and mouse NTPDase1 by mixed type inhibition, predominantly competitive with Ki values 95% purity) using solvent system II (60 mM ammonium phosphate (A) and 5 mM TBAP in 90% water/10% methanol (B), applying a gradient of 25% A to 75% A in 20 min), tR = 6 min (>97% purity). (dadospdf.com)

19851

• Br Med J. 1985;290: 744-5. (journalahrj.com)

Substrate2

• A novel method for analysing 5′ nucleotidase activity of rainbow trout, Oncorhynchus mykiss, head kidney macrophages was optimised for use with cell monolayers, with respect to the effect of cell numbers, temperature and substrate concentration. (elsevier.com)
• Maximal 5′ nucleotidase activity was found in the range 27-33°C and using a substrate concentration of ≥ 1·5 μmol AMP ml -1 for whole cells and ≥1·5 μmol AMP ml -1 for lysed cells. (elsevier.com)

Snake venom1

• Concanavalin A inhibits the interaction of snake venom 5'-nucleotidase and actin. (mpg.de)

Nucleotides2

• [ 1 ] It facilitates the hydrolysis of the phosphate group from 5'-nucleotides, resulting in corresponding nucleosides. (medscape.com)
• The first step in the catabolic pathway is the removal of the 5-phosphate group catalysed by a phosphatase that hydrolyses the nucleotides into nucleosides. (lde225.info)

Liver1

• In most cases there are elevations in both liver and bone isoenzymes, and (rarely) in intestinal isoenzymes [ 5,8 ]. (houstonwehaveaproblemblog.com)

Molecular2

• Molecular cloning and biochemical characterization of a 3'(2'),5'-bisphosphate nucleotidase from Debaryomyces hansenii. (princeton.edu)
• Novel 3'-phosphoadenosine-5'-phosphatases from extremely halotolerant Hortaea werneckii reveal insight into molecular determinants of salt tolerance of black yeasts. (princeton.edu)

Activity is significantly1

• 5'-Nucleotidase activity is significantly stimulated by the addition of particular divalent metal ions, most notably cobalt which results in a 30-50 fold increase in activity. (edu.au)

Serotonin1

• Although the compound has been studied extensively for its neuronal handling and synaptic actions, serotonin 5-HT receptors can be found extra-synaptically and not only in neurons but in many types of mammalian cells, inside and outside the central nervous system (CNS). (frontiersin.org)

Swissprot1

• Compositional properties of 5'-nucleotidase SurE (bottom) versus UniprotKB/SwissProt (top). (ucy.ac.cy)

Clinical1

• The clinical biochemistry of 5′-nucleotidase. (medscape.com)

Kinetic1

• The seven selected residues were modified by site-directed mutagenesis, and the effect of the amino acid substitutions upon the kinetic properties of 5'-nucleotidase activity was determined. (edu.au)

Vibrio1

• anion-activated 5'-nucleotidase in cell envelopes of a slightly halophilic vibrio alginolyticus. (liverpool.ac.uk)