5 amino 3 5 nitro 2 furyl vinyl 1 2 4 oxadiazole. Medical search

A nitrovinyl furan used as a schistosomicidal agent and proposed for trypanosomiasis, especially Chagas disease.

A gas that has been used as an aerosol propellant and is the starting material for polyvinyl resins. Toxicity studies have shown various adverse effects, particularly the occurrence of liver neoplasms.

Compounds having the nitro group, -NO2, attached to carbon. When attached to nitrogen they are nitramines and attached to oxygen they are NITRATES.

A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.

An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.

A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81)

The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.

The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.

A subclass of adenosine A2 receptors found in LEUKOCYTES, the SPLEEN, the THYMUS and a variety of other tissues. It is generally considered to be a receptor for ADENOSINE that couples to the GS, STIMULATORY G-PROTEIN.

Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)

Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).

Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.

Compounds that selectively bind to and block the activation of ADENOSINE A2 RECEPTORS.

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases, the latter causing neutrophils to reduce the dye; used to confirm diagnosis of chronic granulomatous disease.

Compounds that selectively bind to and activate ADENOSINE A2 RECEPTORS.

Enzymes which reduce nitro groups (NITRO COMPOUNDS) and other nitrogenous compounds.

Used formerly as antimicrobial food additive. It causes mutations in many cell cultures and may be carcinogenic.

Compounds that bind to and block the stimulation of PURINERGIC P1 RECEPTORS.

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

A polyvinyl resin used extensively in the manufacture of plastics, including medical devices, tubing, and other packaging. It is also used as a rubber substitute.

Flavoring agent and non-nutritive sweetener.

A class of cell surface receptors that prefer ADENOSINE to other endogenous PURINES. Purinergic P1 receptors are widespread in the body including the cardiovascular, respiratory, immune, and nervous systems. There are at least two pharmacologically distinguishable types (A1 and A2, or Ri and Ra).

Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.

The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.

Compounds that bind to and stimulate PURINERGIC P1 RECEPTORS.

A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.

Agents that reduce the frequency or rate of spontaneous or induced mutations independently of the mechanism involved.

Tumors or cancer of the URINARY BLADDER.

A plant genus of the family APIACEAE. It contains pungent oils and resins. It is used to flavor curries, as a carminative, and as cat and dog repellent. The occasionally used common name of 'giant fennel' should not be confused with true fennel (FOENICULUM).

A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed)

A stable adenosine A1 and A2 receptor agonist. Experimentally, it inhibits cAMP and cGMP phosphodiesterase activity.

Inflammation of the KIDNEY PELVIS and KIDNEY CALICES where urine is collected before discharge, but does not involve the renal parenchyma (the NEPHRONS) where urine is processed.

A 2,4,6-trinitrotoluene, which is an explosive chemical that can cause skin irritation and other toxic consequences.

A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.

Purine bases found in body tissues and fluids and in some plants.

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

A thermostable extracellular metalloendopeptidase containing four calcium ions. (Enzyme Nomenclature, 1992) 3.4.24.27.

The rate dynamics in chemical or physical systems.

The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.

A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)

Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran.

Inorganic compounds that contain nitrogen as an integral part of the molecule.

The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.

A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of tissues including the BRAIN and DORSAL HORN NEURONS. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.

A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.

A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).

Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.

A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell, especially a fluid containing fragrant natural oils extracted from flowers, woods, etc., or similar synthetic oils. (Random House Unabridged Dictionary, 2d ed)

The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

A genus of flagellate EUKARYOTES possessing three long anterior flagella.

Toxic chlorinated unsaturated hydrocarbons. Include both the 1,1- and 1,2-dichloro isomers. Both isomers are toxic, but 1,1-dichloroethylene is the more potent CNS depressant and hepatotoxin. It is used in the manufacture of thermoplastic polymers.

Antineoplastic agent that is also used as a veterinary anesthetic. It has also been used as an intermediate in organic synthesis. Urethane is suspected to be a carcinogen.

... oxadiazoles MeSH D03.383.129.462.580.200 - 5-amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole MeSH D03.383.129.462.580.400 - 4 ... vinyl)-1,2,4-oxadiazole MeSH D03.383.312.649.290 - fanft MeSH D03.383.312.649.308 - furagin MeSH D03.383.312.649.313 - ... alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid MeSH D03.383.129.385.162 - cycloserine MeSH D03.383.129.385.231 - ... 2,3,4,5-tetrahydro-8-chloro-3-methyl-5-phenyl-1h-3-benzazepin-7-ol MeSH D03.438.079.800 - 2,3,4,5-tetrahydro-7,8-dihydroxy-1- ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D03)

... vinyl)-1,2,4-oxadiazole. A nitrovinyl furan used as a schistosomicidal agent and proposed for trypanosomiasis, especially ... A phase 2 clinical trial to evaluate the the efficacy of different benznidazole regimens (300mg/day for 60 days, 150mg/day for ... Only benznidazole (Bnz) (1) and nifurtimox (Nfx) (2) are licensed for the treatment of Chagas disease although their safety and ...

https://www.bioportfolio.com/resources/pmarticle/2422162/Nanocarriers-For-Effective-Delivery-Of-Benznidazole-And-Nifurtimox-In-The-Treatment-Of.html

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D03)

Oxadiazoles (1972-1974). Vinyl Compounds (1972-1974). Public MeSH Note:. 2005; see SQ-19506 1991-2004; see NITROFURANS 1975- ... Nitro Compounds * Nitrofurans [D02.640.600] Nitrofurans * 5 Amino 3 ((5 nitro 2 furyl)vinyl) 1,2,4 oxadiazole [D02.640.600.200 ... 5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole - Preferred Concept UI. M0352073. ... CAS Type 1 Name:. 1,2,4-Oxadiazol-5-amine, 3-(2-(5-nitro-2-furanyl)ethenyl)-, (E)- ...

https://decs.bvsalud.org/en/ths/resource/?id=13569

D12 - AMINO ACIDS, PEPTIDES, AND PROTEINS. Adaptor Proteins. Adaptor Proteins, Vesicular Transport. ... vinyl)-1,2,4-oxadiazole. D03 - HETEROCYCLIC COMPOUNDS. Bay-K-8644. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro- ... 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone. Ro 4-1284. 2H-Benzo(a)quinolizin-2-ol 2-Ethyl-1,3,4,6,7,11b-hexahydro-3- ... Pregnancy-Specific beta 1-Glycoprotein. Pregnancy-Specific beta 1-Glycoproteins. Tissue Inhibitor of-Metalloproteinase-3. ...

http://decs2009.bvsalud.org/I/rep_i2005.htm

Nitro Compounds [D02.640]. *Nitrofurans [D02.640.600]. *Heterocyclic Compounds [D03]. *Heterocyclic Compounds, 1-Ring [D03.383] ... 5-Nitrofurans and Cancer: Teaching an Old Drug New Tricks. Cell Chem Biol. 2018 12 20; 25(12):1439-1440. ... vinyl)-1,2,4-oxadiazole. *FANFT. *Furagin. *Furazolidone ...

https://connects.catalyst.harvard.edu/Profiles/display/Concept/Nitrofurans

... vinyl)-1,2,4-oxadiazole S1P Receptor use Receptors, Lysosphingolipid ... SAP Kinase 3 use Mitogen-Activated Protein Kinase 12 SAP Kinase Extracellular Signal Regulated Kinase Kinase 1 use MAP Kinase ... SAP Kinase-3 use Mitogen-Activated Protein Kinase 12 SAP Kinase-Extracellular Signal-Regulated Kinase Kinase 1 use MAP Kinase ... S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid use Amifostine S-100 Calcium-Binding Protein beta Subunit use S100 ...

http://decs2017.bvsalud.org/I/DeCS2017_Alfab-S.htm

... vinyl]-1,3,4-oxadiazole. 2B. 7, Sup 7. 1987. ... A-alpha-C (2-Amino-9H -pyrido[2,3-è ]indole). 2B. 40, Sup 7. ... 3. 10, Sup 7. 1987. 27208-37-3. Cyclopenta[crf ]pyrene. 2A. Sup 7, 92. 2010. NB: Overall evaluation upgraded to Group 2A with ... 33229-34-4. HC Blue No. 2. 3. 57. 1993. 33419-42-0. Etoposide. 1. 76, 100A. 2012. NB: Overall evaluation upgraded to Group 1 ... 1-tert -Butoxypropan-2-ol. 2B. 88, 119. In prep.. 57117-31-4. 2,3,4,7,8-Pentachlorodibenzofuran. 1. 100F. 2012. NB: Overall ...

https://reformadoresdasaude.com/conhecimento/index.php?sis=374&per=SC1-E2012-E

... amino]ethyl}amino)ethanol; [0070] N-(3-methoxyphenyl)-4-propoxybenzamide; [0071] 2-(4-hydroxyphenyl)-3-phenyl-2,3-dihydro-4(1H ... vinyl]b- enzamide; [0054] 2-chloro-N-(3-chloro-4-methoxyphenyl)benzamide; [0055] 2,6-di-tert-butyl-4-(2,3-dihydro-1H-perimidin- ... furyl}-1H-isoindole-1,3(2H)-dione; [0068] N-(2,5-dimethylphenyl)-3-(4-methoxyphenyl)acrylamide; [0069] 2-({2-[(4-nitrophenyl) ... oxadiazole 38 ##STR00052## 272.1 C9 H7 Cl2 N5 O N-(3,4-dichlorophenyl)- N-4H-1,2,4-triazol-4- ylurea 52 ##STR00053## 475.9 C27 ...

http://www.patentsencyclopedia.com/app/20110212974

... an amino group having from 0 to 50 carbon atoms (e.g., amino, methylamino, diethylamino, diisopropylamino, anilino, or ... 4,960,681 and JP-A-62-245260, specifically, a homopolymer of vinyl monomer having --COOM or --SO3 M (wherein M represents a ... a nitro group, a carboxy group, a hydroxy group, a sulfo group, a mercapto group, an alkylsulfinyl group having from 1 to 50 ... an aliphatic amino group, an arylamino group, a heterocyclic amino group, an aliphatic oxycarbonylamino group, an ...

http://www.freepatentsonline.com/6265117.html

... vinyl)-1,2,4-oxadiazole/therapeutic use , Adult , Animals , Antimony/therapeutic use , Child , Cricetinae , Humans , Hycanthone ... It is administered intramuscularly at a dose of 1 ml per 10 kg body weight with a maximum of 5 ml every other day after 2 ... Southeast Asian J Trop Med Public Health ; 1976 Jun; 7(2): 348-50 ... Southeast Asian J Trop Med Public Health ; 1976 Jun; 7(2): 310-3 ... 1. Effects of ambilhar on the pregnant female rats and their ...

https://search.bvsalud.org/gim/?lang=en&q=mh:Niridazole/adverse+effects

3/4 Inch Concrete Chisel, 1 Inch Cold Chisel, 3 Inch Floor Chisel, 4 Inch Brick Chisel, 3 Pound Deadblow Hammer, & 3 Pound Club ... Vinyl cyclohexenedioxide),Vinyl cyclohexene dioxide (4-Vinyl-1-cyclohexene diepoxide),Vinyl fluoride,"Vinylidene chloride ,(1,1 ... nitro-N-nitrosoguanidine,N-Methylolacrylamide,N-Methylpyrrolidone,à-Methyl styrene (alpha-Methylstyrene),à-Methyl styrene ... amino]-2-oxazolidinone, MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone),Myclobutanil,beta-Myrcene,Nabam,Nafarelin ...

https://www.carbourtools.com/collections/current-promotions/products/6-pc-hardscapers-chisel-bundle-3-4-1-3-and-4-inch-chisels-with-deadblow-and-club-hammers-bundle-and-save

Vinyl cyclohexenedioxide),Vinyl cyclohexene dioxide (4-Vinyl-1-cyclohexene diepoxide),Vinyl fluoride,"Vinylidene chloride ,(1,1 ... nitro-N-nitrosoguanidine,N-Methylolacrylamide,N-Methylpyrrolidone,à-Methyl styrene (alpha-Methylstyrene),à-Methyl styrene ... amino]-2-oxazolidinone, MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone),Myclobutanil,beta-Myrcene,Nabam,Nafarelin ... Vinyl bromide,Vinyl chloride,4-Vinylcyclohexene,4-Vinylcyclohexene,4-Vinyl-1-cyclohexene diepoxide ( ...

https://www.carbourtools.com/products/ox-4-5-inch-stainless-steel-concrete-finishing-trowels

https://carbourtools.com/collections/all-brick-laying-masonry-hand-tools-from-carbour-tools/products/ox-8-5-8-x-3-5-8-inch-non-marking-brick-joint-roller-raker

Vinyl bromide, Vinyl chloride, Vinyl cyclohexene dioxide, Vinyl fluoride, Vinyl trichloride (1,1,2-Trichloroethane), Warfarin, ... nitro-N-nitrosoguanidine, N-Methylolacrylamide, N-Methylpyrrolidone, N-Nitroso-N-ethylurea, N-Nitroso-N-methylurea, N-Nitroso-N ... amino]-2-oxazolidinone, 5-Chloro-o-toluidine and its strong acid salts, 5-Methoxypsoralen with ultraviolet A therapy, 5- ... Vinyl bromide, Vinyl chloride, Vinyl cyclohexene dioxide, Vinyl fluoride, Vinyl trichloride (1,1,2-Trichloroethane), Warfarin, ...

https://oag.ca.gov/prop65/60-day-notice-search-results?field_prop65_report_year_value=&%3Bamp%3Bfield_prop65_id_value=&%3Bamp%3Bfield_prop65_plaintiff_value=&%3Bamp%3Bfield_prop65_defendant_value=&%3Bamp%3Bdate_filter%5Bmin%5D%5Bdate%5D=&%3Bamp%3Bdate_filter%5Bmax%5D%5Bdate%5D=&%3Bamp%3Bfield_prop65_product_value=children&%3Bamp%3Bsort_by=field_prop65_id_value&%3Bamp%3Bitems_per_page=20&%3Bamp%3Bpage=8&%3Bpage=5&page=8

... vinyl chloride/vinyl acetate copolymers, polyvinyl acetate, polyvinylidene chloride, polyarylate, polycarbonate, cellulose ... 6) amino groups substituted with an alkyl group, which have a formula, --N(R.sub.110) (R.sub.111). [0220] Specific examples of ... 0191] Specific examples of the heterocyclic ring groups include thienyl groups, benzothienyl groups, furyl groups, benzofuryl ... 0164] Specific examples of the positive-hole transport materials include oxazole derivatives, oxadiazole derivatives, imidazole ...

http://patents.com/us-20040185358.html

... nitro-2-furyl)-s-triazine- 2,4-diyl]bisacetamide ... amino]-2-imidazolidinone. 3775-55-1 2-amino-5-(5-nitro-2-furyl ... vinyl]-1,3,4-oxadiazole. 66-75-1 ... anti-4,5-dihydroxy-6,6a-epoxy-4,5,6,6a-tetrahydrobenzo[j] ...

http://sciencereview.silentspring.org/mamm_browse.cfm

... vinyl]-1,3,4-oxadiazole Office of Environmental Health Hazard Assessment. Proposition 65 No Significant Risk Levels (NSRLs) for ... amino]-2-imidazolidinone N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide Office of Environmental Health Hazard Assessment. ... Vinyl trichloride (1,1,2-Trichloroethane) a Where a source or product results in exposures by multiple routes, the total ... amino]-2-oxazolidinone MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone) Nickel refinery dust from the pyrometallurgical ...

http://drugstorepdfsearch.com/t/testrust.com1.html

Vinyl cyclohexene dioxide). n-vinyl pyrollidone. Vinyl trichloride (1,1,2-Trichloroethane) X. 2,6-Xylidine (2,6-Dimethylaniline ... N-Methyl-N-nitro-N-nitrosoguanidine (MNNG). N-Methyl-N-nitrosourea. N-Methylolacrylamide. Methylthiouracil. Metiram. ... amino]-2-oxazolidinone. Mustard gas N. Nafenopin. 1-Naphthylamine. 2-Naphthylamine. 3-Naphthylamine. Nickel and certain nickel ... oxadiazole. 7,12-Dimethylbenz(a)anthracene. 3,3-Dimethylbenzidine (ortho-Tolidine). 3,3-Dimethylbenzidine dihydrochloride. ...

http://www.ehso.com/carcinogens.php

... vinyl]-1,3,4- oxadiazole 7,12-Dimethylbenz(a)anthracene ... N-Methyl-N-nitro-N-nitrosoguanidine (MNNG) *N-Methyl-N- ... amino]-2-imidazollidinone *1-[(5-Nitrofurfurylidene)-N-[4-(5-Nitro-2-furyl)-2 thiazolyl]acetamide ... 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) (Lomustine) *1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl ... 3,3-Dimethoxybenzidine (ortho-Dianisidine) *3,3-Dimethoxybenzidine dihydrochloride (ortho-dianisidine dihydrochloride) para- ...

http://lehman.edu/administration/environmental-health-safety/carcinogens-chemicals.php

Vinyl bromide. Epichlorohydrin. Vinyl chloride. Ethyl acrylate. Vinyl cyclohexene dioxide. Ethylene dibromide. Vinylidene ... N-Methyl-N-nitro-N-nitrosoguanidine. Metronidazole. Mirex. Nickel. Nickel acetate. Nickel carbonate. Nickel carbonyl. Nickel ... furyl)acrylamide]. 1,2-Diethylhydrazine. Aflatoxin M1. Diglycidyl resorcinol ether. para-Aminoazobenzene. Dihydrosafrole. ortho ... Vinyl bromide. Diesel exhaust. Vinyl fluoride. Table 2: Các hóa chất có nguy cơ gây ung thư trong cơng nghiệp được liệt. kê bởi ...

https://toc.123doc.org/document/2674143-cac-hoa-chat-gay-ung-thu.htm

furyl)vinyl]-1,3,4-oxadiazole. 7,12-Dimethylbenz(a)anthracene 3,3-Dimethylbenzidine (ortho-Tolidine) 3,3-Dimethylbenzidine ... amino]-2-oxazolidinone. Mustard Gas MX (3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone). N. Nafenopin Nalidixic acid ... N-Methyl-N-nitro-N-nitrosoguanidine N-Methylolacrylamide Methylthiouracil Metiram Metronidazole Michlers ketone Mirex ... Vinyl cyclohexene dioxide) Vinyl fluoride Vinyl trichloride (1,1,2-Trichloroethane) X. 2,6-Xylidine (2,6-Dimethylaniline) Z. ...

https://www.organoderm.com/category-s/1831.htm

Methyl vinyl sulfone3680-02-2. Methyl(1S,3S,4R)-2-[(R) -1-phenylethyl]-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylate130194-96-6 ... 6-Amino-2,2-dimethyl-2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one1002726-62-6 ... 2R, 2S)-6-Fluoro-2-(2oxiranyl)chromane129050-26-6. (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile207557-35-5 ... Amino]-1,3-Thiazole-4-Carboxylate185105-98-0. Ethyl 2-[3-formyl-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylate161798 ...

https://www.viochemicals.com/products

Ethyl Phenyl Compounds Acid Ether Pyridine ACIDS Nitrofurans Alkyl Polymer Nitrogen 1974 Substituent 1988 Phosphine sulfide Proteins 1990 1987 Compound

5. The process of claim 4, wherein R.sup.1 is n-propyl, R.sup.2 is ethyl, and Z is 3-trifluoromethylphenyl. (patentgenius.com)
13. The process of claim 12, wherein R.sup.1 is n-propyl, R.sup.2 is ethyl, and Z is 3-trifluoromethylphenyl, namely 3-ethyl-1-propyl-8-{1-[(3-trifluoromethylphenyl)methyl]pyrazol-4yl}-1,3,7- -trihydropurine-2,6-dione. (patentgenius.com)
19. The process of claim 18, wherein R.sup.1 is n-propyl, R.sup.2 is ethyl, and Z is 3-trifluoromethylphenyl. (patentgenius.com)
4-(2-Chloroacetyl)Methanesulfonanilide Ethyl 2-(2-Aminothiazole-4-Yl)-2-Methoxyiminoacetate Ethyl 2-(2-Aminothiazole-4-Yl)-2-Hydroxyiminoacetate 5-Acetyloxindole. (twfta.com)

4. The process of claim 3, wherein R.sup.1 and R.sup.2 are independently lower alkyl, Y is methylene, and Z is optionally substituted phenyl. (patentgenius.com)
12. The process of claim 6, wherein R.sup.1 and R.sup.2 are independently lower alkyl, X is pyrazol-4-yl, Y is methylene, and Z is optionally substituted phenyl. (patentgenius.com)
18. The process of claim 17, wherein R.sup.1 and R.sup.2 are independently lower alkyl, X is pyrazol-4-yl, Y is methylene, and Z is optionally substituted phenyl. (patentgenius.com)

It is known that the compounds of the general formulas (I), (III) and (IV) of claim 2 have a nociceptin antagonism and are useful as the analgesic (International Publications WO01/72710, WO98/54168 and WO99/48492). (justia.com)
More specifically, they have found that the compound of the general formula (II) of claim 2 has a nociceptin antagonism and also has an antipruritic effect, and that the compounds of the general formulas (I), (III) and (IV) of claim 2 known to have a nociceptin antagonism have an antipruritic effect. (justia.com)
This invention relates to pyrazole compounds that inhibit or modulate the activity of cyclin dependent kinases (CDK) and glycogen synthase kinase-3 (GSK-3), to the use of the compounds in the treatment or prophylaxis of disease states or conditions mediated by cyclin dependent kinases and glycogen synthase kinase-3, and to novel compounds having cyclin dependent kinase or glycogen synthase kinase-3 inhibitory or modulating activity. (allindianpatents.com)
SUBSTANCE: compounds are suitable for use as kinase 1β-adrenergic receptor (βARK-1) inhibitors. (russianpatents.com)

20. The method according to claim 16, wherein said DOCK5 protein refers to a polypeptide comprising the DHR2 domain of the protein DOCK5 corresponding to the amino acid 1132 to 1661 of the DOCK5 protein from Mus musculus SEQ ID NO:1 and derivatives thereof. (patentsencyclopedia.com)
5. The electroconductive polymer composition according to claim 1, further comprising polystyrene sulfonic acid as dopant. (patents.com)
All of these receptors are broadly distributed in cells and tissues throughout the body, but SI Pi, SI P3 and S1P4 are predominantly expressed in lymphocyte and endothelial cell, SIP2 is predominantly expressed in vascular smooth muscle cell, and SIP5 is predominantly expressed in brain and spleen, and amino acid sequences thereof are well-conserved in human and rodent (Non-Patent Document 1). (allindianpatents.com)
For example, as a compound having SIPi agonist activity, a carboxylic acid derivative represented by the following formula has been known (Patent Document 1). (allindianpatents.com)

Bis(chloroethyl) ether is a chemical compound (an ether), which contains two 2-chloroethyl groups. (chemchart.com)

Pyridine was discovered in 1. (chemchart.com)

Cyclins are a family of proteins characterised by a homology region, containing approximately 100 amino acids, termed the "cyclin box" which is used in binding to, and defining selectivity for, specific CDK partner proteins. (allindianpatents.com)
The binding of Gβγ is approximately the area length of 100 amino acids, which is part of plastikowego homology (PH) domain, found in ARTICLE GRK2. (russianpatents.com)

5-Nitrofurans and Cancer: Teaching an Old Drug New Tricks. (harvard.edu)

In Formulae (I) to (IV), R.sup.1 to R.sup.12 each independently represent a hydrogen atom, an alkyl group, an aryl group or a heteroaryl group. (patents.com)

1. An electroconductive polymer composition comprising an electroconductive polymer having an electroconductivity of 10.sup. (patents.com)
6. The electroconductive polymer composition according to claim 1, further comprising water to be in a state of dispersion. (patents.com)
and a layer formed by using the electroconductive polymer composition according to claim 1 on or above the support. (patents.com)
4. A material according to claim 2 , characterized in that the onium cation is part of a recurring unit of a polymer. (google.com)

5. A material according to claim 2 , characterized in that the cation M is a cationic heterocycle with aromatic character, including at least one alkylated nitrogen atom in the cycle. (google.com)
Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions. (ctdbase.org)

Variation of Levodopa Metabolism with Gastrointestinal-Absorption Site," The Lancet, 1(7851):238-240 (1974). (patentgenius.com)
4 (1974) (corr. (who.int)

3. A material according to claim 2 , characterized in that the onium cation is part of the Y c or the substituent Q. (google.com)

5(9):587-591 (1988). (patentgenius.com)

NSRL (µg/day)a MADL (µg/day)a 2,3,7,8-Tetrachlorodibenzo- p -dioxin (TCDD) Tris(1-aziridinyl)phosphine sulfide (Thiotepa) Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) Vinyl trichloride (1,1,2-Trichloroethane) a Where a source or product results in exposures by multiple routes, the total exposure must be considered. (drugstorepdfsearch.com)

Many receptors bind to G proteins by stimulation of sphingosine-1-phosphate. (allindianpatents.com)
The Janus kinase (JAK) family of tyrosine kinases (JAK l, 2, 3, and Thy 1) is activated by interaction with other proteins (see O'shea, J.J. et al. (russianpatents.com)

7(4):384-387 (1990). (patentgenius.com)

14(3):201-240 (1987). (patentgenius.com)

1. A negative-working presensitized plate useful for preparing a lithographic printing plate having a negative-working photosensitive layer on an aluminum substrate, which comprises an intermediate layer comprising a compound having one diazonium group and a molecular weight of 1000 or less formed between said photosensitive layer and said aluminum substrate. (google.com.au)
As a compound having SI Pi agonist activity, an indane derivative represented by the following formula has been known (Patent Document 2). (allindianpatents.com)
As a compound having SIPi agonist activity, an oxadiazole derivative represented as follows has been known (following figure, Patent Documents 3, 4, 5, and 6). (allindianpatents.com)
the compound is further comprised of M as a hydroxonium, a nitrosonium NO + , an ammonium -NH 4 + , a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. (google.com)
Diethanolamine, often abbreviated as DEA or DEOA, is an organic compound with the formula HN(CH2CH2OH)2. (chemchart.com)
SUBSTANCE: invention relates to a compound, which is N3-1H-indol-5-yl-5-pyridin-4-ylpyrazine-2,3-diamine, or a pharmaceutically acceptable salt thereof, which can act as inhibitors of protein kinase, especially FLT3 tyrosine kinase. (russianpatents.com)

Anatomy1

Organisms2

Diseases4

Chemicals and Drugs48

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Phenomena and Processes7

Technology, Industry, Agriculture3

5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole

Oxadiazoles

Vinyl Compounds

Vinyl Chloride

Nitro Compounds

FANFT

Nitrofurans

Thiadiazoles

Quinoxalines

Guanylate Cyclase

Nitric Oxide Donors

Molecular Structure

Structure-Activity Relationship

Receptor, Adenosine A2A

Cyclic GMP

Magnetic Resonance Spectroscopy

Amino Acids

Adenosine A2 Receptor Antagonists

Antifungal Agents

Polyvinyls

Nitric Oxide

Nitroblue Tetrazolium

Thiazoles

Adenosine A2 Receptor Agonists

Nitroreductases

Furylfuramide

Purinergic P1 Receptor Antagonists

Enzyme Inhibitors

Polyvinyl Chloride

Saccharin

Triazoles

Receptors, Purinergic P1

Triazines

Sequence Homology, Amino Acid

Purinergic P1 Receptor Agonists

Polyvinyl Alcohol

Antimutagenic Agents

Urinary Bladder Neoplasms

Ferula

Phenethylamines

Adenosine-5'-(N-ethylcarboxamide)

Pyelitis

Trinitrotoluene

Acrylates

Adenosine

Xanthines

Carcinogens

Thermolysin

Kinetics

Amino Acid Substitution

Hemangiosarcoma

Furans

Nitrogen Compounds

Cloning, Molecular

Receptor, Adenosine A1

Urinary Bladder

Oxidation-Reduction

Neoplasms, Experimental

Perfume

Stereoisomerism

Tritrichomonas

Indazoles

Dichloroethylenes

Urethane

List of MeSH codes (D03)

NANOCARRIERS FOR EFFECTIVE DELIVERY OF BENZNIDAZOLE AND NIFURTIMOX IN THE TREATMENT OF CHAGAS DISEASE: A REVIEW.

List of MeSH codes (D03) - Wikipedia

DeCS

DeCS 2005 - Changed terms

Nitrofurans | Harvard Catalyst Profiles | Harvard Catalyst

DeCS 2017 - July 04, 2017 version

Tabla de agentes carcinógenos

METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS - Patent application

Color imaging element and method of forming color diffusion transfer image - Fuji Photo Film Co., Ltd.

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Application # 2004/0185358. Electrophotographic photoreceptor, method for manufacturing the electrophotographic...