Pichia: Yeast-like ascomycetous fungi of the family Saccharomycetaceae, order SACCHAROMYCETALES isolated from exuded tree sap.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Information Storage and Retrieval: Organized activities related to the storage, location, search, and retrieval of information.Barth Syndrome: Rare congenital X-linked disorder of lipid metabolism. Barth syndrome is transmitted in an X-linked recessive pattern. The syndrome is characterized by muscular weakness, growth retardation, DILATED CARDIOMYOPATHY, variable NEUTROPENIA, 3-methylglutaconic aciduria (type II) and decreases in mitochondrial CARDIOLIPIN level. Other biochemical and morphological mitochondrial abnormalities also exist.Tripterygium: A plant genus of the family CELASTRACEAE that is a source of triterpenoids and diterpene epoxides such as triptolide.Medication Adherence: Voluntary cooperation of the patient in taking drugs or medicine as prescribed. This includes timing, dosage, and frequency.Mice, Inbred mdx: A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Programming Languages: Specific languages used to prepare computer programs.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Templates, Genetic: Macromolecular molds for the synthesis of complementary macromolecules, as in DNA REPLICATION; GENETIC TRANSCRIPTION of DNA to RNA, and GENETIC TRANSLATION of RNA into POLYPEPTIDES.Civilization: The distinctly human attributes and attainments of a particular society.Sinorhizobium meliloti: A species of gram-negative, aerobic bacteria that causes formation of root nodules on some, but not all, types of sweet clover, MEDICAGO SATIVA, and fenugreek.Acyl-Butyrolactones: Cyclic esters of acylated BUTYRIC ACID containing four carbons in the ring.Quorum Sensing: A phenomenon where microorganisms communicate and coordinate their behavior by the accumulation of signaling molecules. A reaction occurs when a substance accumulates to a sufficient concentration. This is most commonly seen in bacteria.L-Aminoadipate-Semialdehyde Dehydrogenase: An enzyme that catalyzes the oxidation of L-2-aminoadipate 6-semialdehyde to L-2-aminoadipate (alpha-aminoadipic acid). It is involved in the biosynthetic pathway of LYSINE.Cysteine Synthase: An enzyme that catalyzes the biosynthesis of cysteine in microorganisms and plants from O-acetyl-L-serine and hydrogen sulfide. This enzyme was formerly listed as EC 4.2.99.8.Glutamate Dehydrogenase: An enzyme that catalyzes the conversion of L-glutamate and water to 2-oxoglutarate and NH3 in the presence of NAD+. (From Enzyme Nomenclature, 1992) EC 1.4.1.2.Amino Acids, Sulfur2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).Neurospora: A genus of ascomycetous fungi, family Sordariaceae, order SORDARIALES, comprising bread molds. They are capable of converting tryptophan to nicotinic acid and are used extensively in genetic and enzyme research. (Dorland, 27th ed)Neurospora crassa: A species of ascomycetous fungi of the family Sordariaceae, order SORDARIALES, much used in biochemical, genetic, and physiologic studies.Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.Lysine: An essential amino acid. It is often added to animal feed.NAD: A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)4-Nitrophenylphosphatase: An enzyme that catalyzes the hydrolysis of nitrophenyl phosphates to nitrophenols. At acid pH it is probably ACID PHOSPHATASE (EC 3.1.3.2); at alkaline pH it is probably ALKALINE PHOSPHATASE (EC 3.1.3.1). EC 3.1.3.41.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Caenorhabditis elegans: A species of nematode that is widely used in biological, biochemical, and genetic studies.Central Nervous System Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Nervous System Neoplasms: Benign and malignant neoplastic processes arising from or involving components of the central, peripheral, and autonomic nervous systems, cranial nerves, and meninges. Included in this category are primary and metastatic nervous system neoplasms.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.Reagent Kits, Diagnostic: Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Hydroxymethylglutaryl CoA Reductases: Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.Biosensing Techniques: Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Corpora Allata: Paired or fused ganglion-like bodies in the head of insects. The bodies secrete hormones important in the regulation of metamorphosis and the development of some adult tissues.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Micronesia: The collective name for islands of the Pacific Ocean east of the Philippines, including the Mariana, PALAU, Caroline, Marshall, and Kiribati Islands. (From Webster's New Geographical Dictionary, 1988, p761 & Room, Brewer's Dictionary of Names, 1992, p350)Immunoglobulin M: A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.NitrophenolsOrganophosphorus Compounds: Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.Salts: Substances produced from the reaction between acids and bases; compounds consisting of a metal (positive) and nonmetal (negative) radical. (Grant & Hackh's Chemical Dictionary, 5th ed)Potassium Compounds: Inorganic compounds that contain potassium as an integral part of the molecule.Potassium: An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.Alkaline Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.Alkanesulfonic Acids: Sulfonic acid derivatives that are substituted with an aliphatic hydrocarbon group.Phosphates: Inorganic salts of phosphoric acid.Phenylacetates: Derivatives of phenylacetic acid. Included under this heading are a variety of acid forms, salts, esters, and amides that contain the benzeneacetic acid structure. Note that this class of compounds should not be confused with derivatives of phenyl acetate, which contain the PHENOL ester of ACETIC ACID.Science: The study of natural phenomena by observation, measurement, and experimentation.
(1/86) Hyperaldosteronemia in rabbits inhibits the cardiac sarcolemmal Na(+)-K(+) pump.

Aldosterone upregulates the Na(+)-K(+) pump in kidney and colon, classical target organs for the hormone. An effect on pump function in the heart is not firmly established. Because the myocardium contains mineralocorticoid receptors, we examined whether aldosterone has an effect on Na(+)-K(+) pump function in cardiac myocytes. Myocytes were isolated from rabbits given aldosterone via osmotic minipumps and from controls. Electrogenic Na(+)-K(+) pump current, arising from the 3:2 Na(+):K(+) exchange ratio, was measured in single myocytes using the whole-cell patch clamp technique. Treatment with aldosterone induced a decrease in pump current measured when myocytes were dialyzed with patch pipette solution containing Na(+) in a concentration of 10 mmol/L, whereas there was no effect measured when the solution contained 80 mmol/L Na(+). Aldosterone had no effect on myocardial Na(+)-K(+) pump concentration evaluated by vanadate-facilitated [(3)H]ouabain binding or by K(+)-dependent paranitrophenylphosphatase activity in crude homogenates. Aldosterone induced an increase in intracellular Na(+) activity. The aldosterone-induced decrease in pump current and increased intracellular Na(+) were prevented by cotreatment with the mineralocorticoid receptor antagonist spironolactone. Our results indicate that hyperaldosteronemia decreases the apparent Na(+) affinity of the Na(+)-K(+) pump, whereas it has no effect on maximal pump capacity.  (+info)

(2/86) Alphabeta protomers of Na+,K+-ATPase from microsomes of duck salt gland are mostly monomeric: formation of higher oligomers does not modify molecular activity.

The distance that separates alphabeta protomers of the Na(+), K(+)-ATPase in microsomes and in purified membranes prepared from duck nasal salt glands was estimated by measuring fluorescence resonance energy transfer between anthroylouabain bound to a population of alphabeta protomers and either N-[7-nitrobenz-2-oxa-1, 3-diazol-4-yl]-6-aminohexyl ouabain or 5-(and-6)-carboxyfluorescein-6-aminohexyl ouabain bound to the rest. Energy transfer between probes bound in the microsomal preparation was less than in the purified membranes. The efficiency of energy transfer between anthroylouabain and N-[7-nitrobenz-2-oxa-1, 3-diazol-4-yl]-6-aminohexyl ouabain was 29.2% in the microsomes compared with 62.6% in the purified preparation. Similar results were obtained with 5-(and-6)-carboxyfluorescein-6-aminohexyl ouabain as acceptor. We calculate that either the protomer bound probes were on the average 13 A farther apart in the microsomes than in the purified membranes, or that 53% of the protomers are monomeric in the microsome preparation. Microsomes prepared in the presence of phalloidin (a toxin that binds to F actin and stabilizes the actin-based cytoskeleton) showed less quench than those prepared in its absence. The data support the hypothesis that protomers are kept apart by their association with the cytoskeleton. The turnover rate while hydrolyzing ATP is the same in the microsomal and purified preparations; higher oligomer formation has no significant effect on the enzyme reaction mechanism.  (+info)

(3/86) HMG CoA reductase inhibition reduces sarcolemmal Na(+)-K(+) pump density.

OBJECTIVES: HMG CoA reductase inhibitors reduce cellular availability of mevalonate, a precursor in cholesterol synthesis. Since the cholesterol content of cell membranes is an important determinant of Na(+)-K(+) pump function we speculated that treatment with HMG CoA reductase inhibitors affects Na(+)-K(+) pump activity. METHODS: We treated rabbits and rats for 2 weeks with the HMG CoA reductase inhibitor lovastatin and measured Na(+)-K(+) pump current (I(p)) in isolated rabbit cardiac myocytes using the whole cell patch-clamp technique, K-dependent p-nitrophenyl phosphatase (p-NPPase) activity in crude myocardial and skeletal muscle homogenates, and vanadate-facilitated 3H-ouabain binding in intact skeletal muscle samples from rats. RESULTS: Treatment with lovastatin caused statistically significant reductions in I(p), myocardial and skeletal muscle K-dependent p-NPPase activity and 3H-ouabain binding in the myocardium and skeletal muscle. The lovastatin-induced decrease in I(p) was eliminated by parenteral co-administration of mevalonate. However, this was not related to cardiac cholesterol content. CONCLUSIONS: Treatment with lovastatin reduces Na(+)-K(+) pump activity and abundance in rabbit and rat sarcolemma.  (+info)

(4/86) Structural and immunological similarities between high molecular weight zinc ion-dependent p-nitrophenylphosphatase and fructose-1,6-bisphosphate aldolase from bovine liver.

High molecular weight zinc ion-dependent acid p-nitrophenylphosphatase (HMW-ZnAPase) was purified from bovine liver to homogeneity as judged by native and sodium dodecyl sulfate polyacrylamide gel electrophoresis. The partial sequence of the purified enzyme electroblotted on PVDF membrane reveals a 95% sequence homology with human and bovine liver fructose-1,6-bisphosphate aldolase isozyme B (FALD B). FALD B was isolated from bovine liver using an affinity elution from phosphocellulose column. FALD B from bovine liver shows a native and subunit molecular weight that is indistinguishable from that of HMW-ZnAPase. In addition, an affinity purified antiserum raised in rabbits against purified HMW-ZnAPase cross-reacts with bovine liver FALD B and rabbit muscle isozymes. Despite these similarities, HMW-ZnAPase does not show FALD activity and bovine liver FALD does not display any zinc ion-p-nitrophenylphosphatase activity. These results suggested the existence of structural and immunological similarities between bovine liver HMW-ZnAPase and FALD B. Differences in some amino acid residues in enzyme activity indicate that they may be involved in different biochemical functions.  (+info)

(5/86) p-Nitrophenylphosphatase activity catalyzed by plasma membrane (Ca(2+) + Mg(2+)ATPase: correlation with structural changes modulated by glycerol and Ca(2+).

The plasma membrane (Ca(2+) + Mg(2+))ATPase hydrolyzes pseudo-substrates such as p-nitrophenylphosphate. Except when calmodulin is present, Ca(2+) ions inhibit the p-nitrophenylphosphatase activity. In this report it is shown that, in the presence of glycerol, Ca(2+) strongly stimulates phosphatase activity in a dose-dependent manner. The glycerol- and Ca(2+)-induced increase in activity is correlated with modifications in the spectral center of mass (average emission wavenumber) of the intrinsic fluorescence of the enzyme. It is concluded that the synergistic effect of glycerol and Ca(2+) is related to opposite long-term hydration effects on the substrate binding domain and the Ca(2+) binding domain.  (+info)

(6/86) Characterization of a novel mammalian phosphatase having sequence similarity to Schizosaccharomyces pombe PHO2 and Saccharomyces cerevisiae PHO13.

p34, a specific p-nitrophenyl phosphatase (pNPPase) was identified and purified from the murine cell line EL4 in a screen for the intracellular molecular targets of the antiinflammatory natural product parthenolide. A BLAST search analysis revealed that it has a high degree of sequence similarity to two yeast alkaline phosphatases. We have cloned, sequenced, and expressed p34 as a GST-tagged fusion protein in Escherichia coli and an EE-epitope-tagged fusion protein in mammalian cells. Using p-nitrophenyl phosphate (pNPP) as a substrate, p34 is optimally active at pH 7.6 with a K(m) of 1.36 mM and K(cat) of 0.052 min(-1). Addition of 1 mM Mg(2+) to the reaction mixture increases its activity by 14-fold. Other divalent metal ions such as Co(2+) and Mn(2+) also stimulated the activity of the enzyme, while Zn(2+), Fe(2+), and Cu(2+) had no effect. Furthermore, both NaCl and KCl enhanced the activity of the enzyme, having maximal effect at 50 and 75 mM, respectively. The enzyme is inhibited by sodium orthovanadate but not by sodium fluoride or okadaic acid. Mutational analysis data suggest that p34 belongs to the group of phosphatases characterized by the sequence motif DXDX(T/V).  (+info)

(7/86) Transepithelial potential in mesonephric nephrons of 7-day-old chick embryos in relation to the histochemically detected sodium pump.

In order to obtain basic information on the transport properties of differentiating embryonic nephrons, we examined the 7-day-old chick mesonephros by measuring the transtubular epithelial potential difference (TPD) and by histochemical detection of Na,K-ATPase activity. TPD as an indicator of the electrogenic transport was measured in individual segments of superficial nephrons in vivo. Their electric polarity was always lumen-negative. TPD was reduced by addition of 10 mM KCN applied to the mesonephric nephrons from the outside. In the proximal tubules, TPD was significantly lower (mean+/-SD: -1.0+/-0.5 mV) than in the distal and collecting tubules (-2.2+/-1.0 mV, p< or =0.05). Activity of the sodium pump was evaluated histochemically by detection of ouabain-sensitive potassium-dependent p-nitrophenyl phosphatase in cryostat sections of the mesonephros. The enzyme activity was demonstrated only in distal tubules and in the collecting ducts, but not in the proximal tubules. These findings have revealed significant differences between embryonic nephron segments: the distal tubule, in contrast to the proximal one, is supplied by the sodium pump and is able to generate higher TPD. Therefore, we consider that it is only the distal nephron, which possesses the ability of active transport.  (+info)

(8/86) Cytochemistry of protein kinase C and Na-K-ATPase in rabbit ciliary processes treated with phorbol ester.

Immunocytochemical localization of protein kinase C (PKC) in rabbit ciliary processes was investigated using anti-PKC monoclonal antibodies (MAbs) against rabbit Types 1, 2, and 3 PKC. Specific immunolabeling was observed in nonpigmented epithelial (NPE) cells and in the capillaries of the ciliary processes with anti-Types 2 and 3 MAbs. No apparent staining was seen with anti-Type 1 MAbs. Immunoelectron microscopy of Types 2 and 3 MAbs revealed a diffuse distribution of immunoreactive PKC in the cytoplasm, in the nucleus, and on the plasma membrane in the NPE cells. When incubated with phorbol 12-myristate 13-acetate (PMA), the distribution of PKC was basically similar to that of the untreated group. However, the labelling density on the plasma membrane at basolateral interdigitation increased considerably for anti-Types 2 and 3 PKC MAbs. In addition, the enzyme cytochemical activity of Na-K-ATPase (ouabain-sensitive K-NPPase) and its change after PMA administration in the ciliary processes were observed. An intense reaction was seen on the basolateral plasma membrane of the NPE cells. In the PMA-treated group, the enzyme activity of Na-K-ATPase apparently was decreased. These findings provide evidence that PKC plays a crucial role in the function of the NPE cells of the ciliary processes, possibly in aqueous humor production.  (+info)

*  4-nitrophenylphosphatase
Other names in common use include nitrophenyl phosphatase, p-nitrophenylphosphatase, para-nitrophenyl phosphatase, K-pNPPase, ... Attias J, Bonnet JL (1972). "A specific alkaline p-nitrophenylphosphatase activity from baker's yeast". Biochim. Biophys. Acta ... Attias J, Durand H (1973). "Further characterization of a specific p-nitrophenylphosphatase from baker's yeast". Biochim. ... NPPase, PNPPase, Ecto-p-nitrophenyl phosphatase, and p-nitrophenylphosphate phosphohydrolase. This enzyme participates in gamma ...
*  List of MeSH codes (D08)
... map kinase kinase 4 MeSH D08.811.913.696.620.682.700.565.500 --- map kinase kinase 5 MeSH D08.811.913.696.620.682.700.565.600 ... map kinase kinase 4 MeSH D08.811.913.696.620.682.725.200.500 --- map kinase kinase 5 MeSH D08.811.913.696.620.682.725.200.600 ... type 4 MeSH D08.811.913.696.620.682.725.400.050 --- proto-oncogene proteins c-kit MeSH D08.811.913.696.620.682.725.400.075 --- ... 4-beta-glucosidase MeSH D08.811.277.450.420.200.600 --- glucan endo-1,3-beta-d-glucosidase MeSH D08.811.277.450.420.375 --- ...
*  List of EC numbers (EC 3)
EC 3.2.1.91: cellulose 1,4-b-cellobiosidase EC 3.2.1.92: peptidoglycan b-N-acetylmuramidase EC 3.2.1.93: a,a-phosphotrehalase ... 4-b-xylosidase EC 3.2.1.38: b-D-fucosidase EC 3.2.1.39: glucan endo-1,3-b-D-glucosidase EC 3.2.1.40: a-L-rhamnosidase EC 3.2. ... 4-a-glucosidase EC 3.2.1.4: cellulase EC 3.2.1.5: deleted EC 3.2.1.6: endo-1,3(4)-b-glucanase EC 3.2.1.7: inulinase EC 3.2.1.8 ... 4-b-xylanase EC 3.2.1.137: mannan exo-1,2-1,6-a-mannosidase EC 3.2.1.138: now EC 4.2.2.15 EC 3.2.1.139: Alpha-glucuronidase EC ...
4-nitrophenylphosphatase - Wikipedia  4-nitrophenylphosphatase - Wikipedia
Other names in common use include nitrophenyl phosphatase, p-nitrophenylphosphatase, para-nitrophenyl phosphatase, K-pNPPase, ... Attias J, Bonnet JL (1972). "A specific alkaline p-nitrophenylphosphatase activity from baker's yeast". Biochim. Biophys. Acta ... Attias J, Durand H (1973). "Further characterization of a specific p-nitrophenylphosphatase from baker's yeast". Biochim. ... NPPase, PNPPase, Ecto-p-nitrophenyl phosphatase, and p-nitrophenylphosphate phosphohydrolase. This enzyme participates in gamma ...
more infohttps://en.wikipedia.org/wiki/4-nitrophenylphosphatase
EC 3.1.3  EC 3.1.3
... 26 4-phytase. EC 3.1.3.27 phosphatidylglycerophosphatase. EC 3.1.3.28 ADPphosphoglycerate phosphatase. EC 3.1.3.29 N- ... EC 3.1.3.40 guanidinodeoxy-scyllo-inositol-4-phosphatase. EC 3.1.3.41 4-nitrophenylphosphatase. EC 3.1.3.42 [glycogen-synthase- ... EC 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. EC 3.1.3.68 2-deoxyglucose-6-phosphatase. EC 3.1.3.69 ... EC 3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase. EC 3.1.3.58 sugar-terminal-phosphatase. EC 3.1.3.59 ...
more infohttps://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC3/1/3/
Proteinase K cleavage.Pig kidney membranes were incubat | Open-i  Proteinase K cleavage.Pig kidney membranes were incubat | Open-i
Proteinase K cleavage.Pig kidney membranes were incubated in 25/or 1 mM ADP, as indicated. The samples were treated with PK (PK/protein ratio ∼1∶50) and the
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4016139_pone.0096909.g006&req=4
Effect of temperature, pH, and vanadate sensitivity of  | Open-i  Effect of temperature, pH, and vanadate sensitivity of | Open-i
Effect of temperature, pH, and vanadate sensitivity of the CPZ treated enzyme.A. Pig kidney Na+,K+-ATPase activity was measured at four different temperatures,
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4016139_pone.0096909.g004&req=4
Recombinant Human ATP1A1 protein, MYC/DDK-tagged ATP1A1-293H - Creative BioMart  Recombinant Human ATP1A1 protein, MYC/DDK-tagged ATP1A1-293H - Creative BioMart
4-nitrophenylphosphatase activity; ATP binding; ATPase activity, coupled to transmembrane movement of ions, phosphorylative ...
more infohttps://www.creativebiomart.net/recombinant-human-atp1a1-protein-mycddk-tagged-467073.htm
KEGG BRITE: Enzymes - Zunongwangia profunda  KEGG BRITE: Enzymes - Zunongwangia profunda
3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 3.1.3.87 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate ...
more infohttp://www.genome.jp/kegg-bin/get_htext?zpr01000+ZPR_3185
KEGG SSDB Best Search Result: smi:BN406 06279  KEGG SSDB Best Search Result: smi:BN406 06279
cfi:Celf_0823 PHP domain protein K04477 240 110 ( 7) 31 0.321 112 -, 4 cro:ROD_25061 N-acetylmuramic acid 6-phosphate etherase ... aly:ARALYDRAFT_475563 large subunit of riblose-1,5-bisp K01601 479 375 ( 0) 91 0.266 410 -, 4 apak:AP3564_01620 2,3-diketo-5- ... srw:TUE45_02259 putative hydrolase YutF 342 122 ( 4) 34 0.318 195 -, 6 cfl:Cfla_2467 UBA/THIF-type NAD/FAD binding protein 497 ... psos:POS17_0309 dTDP-4-dehydrorhamnose reductase K00067 293 106 ( 3) 30 0.325 83 -, 2 saq:Sare_3653 aldo/keto reductase K05275 ...
more infohttp://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=smi:BN406_06279
Find Research Projects
             - University of Miamis Research Profiles  Find Research Projects - University of Miami's Research Profiles
Powered by Pure, Scopus & Elsevier Fingerprint Engine™ © 2019 Elsevier B.V. We use cookies to help provide and enhance our service and tailor content. By continuing you agree to the use of cookies. Log in to Pure. ...
more infohttps://miami.pure.elsevier.com/en/projects/?format=&page=7
ApiLoc  ApiLoc
PFB0310c (MSP-4, MSP4) merozoite surface protein 4 *PFD1160w (SURFIN4.2, Surf4.2) surface-associated interspersed gene 4.2, ( ... PFD1120c (ETRAMP4, SEP4, Etramp 4, Etramp4) early transcribed membrane protein 4 *PF11_0302 (PV-1) parasitophorous vacuolar ... PFD1120c (ETRAMP4, SEP4, Etramp 4, Etramp4) early transcribed membrane protein 4 *PFD0310w (Pfs16) sexual stage-specific ... PFC0105w (SRPK1, CLK-4) serine/threonine protein kinase, putative *PFI0250c (Nup100) conserved Plasmodium membrane protein, ...
more infohttp://apiloc.biochem.unimelb.edu.au/apiloc/apiloc/species/Plasmodium%20falciparum
List of MeSH codes (D08) - Wikipedia  List of MeSH codes (D08) - Wikipedia
... map kinase kinase 4 MeSH D08.811.913.696.620.682.700.565.500 --- map kinase kinase 5 MeSH D08.811.913.696.620.682.700.565.600 ... map kinase kinase 4 MeSH D08.811.913.696.620.682.725.200.500 --- map kinase kinase 5 MeSH D08.811.913.696.620.682.725.200.600 ... type 4 MeSH D08.811.913.696.620.682.725.400.050 --- proto-oncogene proteins c-kit MeSH D08.811.913.696.620.682.725.400.075 --- ... 4-beta-glucosidase MeSH D08.811.277.450.420.200.600 --- glucan endo-1,3-beta-d-glucosidase MeSH D08.811.277.450.420.375 --- ...
more infohttps://en.wikipedia.org/wiki/List_of_MeSH_codes_(D08)
1vjr - TOPSAN  1vjr - TOPSAN
4. Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard. ... Crystal structure of 4-nitrophenylphosphatase (TM1742) from Thermotoga maritima at 2.40 A resolution. To be published. ... The gene TM1742 from Thermotoga maritima encodes a 4-nitrophenylphosphatase EC:3.1.3.41. The enzyme was previously crystallized ... The enzyme catalyzes the hydrolysis of 4-nitrophenyl phosphate to form 4-nitrophenol. ...
more infohttp://beta.topsan.org/Proteins/JCSG/1vjr
IMP: Integrative Multi-species Prediction  IMP: Integrative Multi-species Prediction
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group). 0.193. ... pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2. 0.111. ... 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans). 0.028. ... solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4. 0.029. ...
more infohttp://imp.princeton.edu/predictions/process_ortho/zebrafish-context-global/10552/
S-table+3 (8-17-07).xls  S-table+3 (8-17-07).xls
4-lactone oxidase, involved in biosynthesis of D-erythroascorbic acid, which has a protective role against oxidative damage; ... 4-Dihydroxy-2-butanone 4-phosphate synthase; homodimeric enzyme of riboflavin biosynthesis; converts ribulose 5-phosphate to L- ... 3,4-dihydroxy-2-butanone 4-phosphate; transcription regulated on yeast-hypha switch; macrophage interaction Inositol phosphoryl ... Gcn4p-regulatedProtein abundance is affected by URA3 expression in the CAI-4 strain background; alkaline upregulated; Gcn4p- ...
more infohttp://medpdfarticles.com/c/candidagenome.org1.html
1734 projects  1734 projects
X-ray diffraction data for the Crystal structure of a putative monooxygenase (YP_001095275.1) from Shewanella loihica PV-4 at ... X-ray diffraction data for the Crystal structure of 4-nitrophenylphosphatase (TM1742) from Thermotoga maritima at 2.40 A ...
more infohttps://proteindiffraction.org/search/?show=100&q=resolution<
ENZYME: 3.-.-.  ENZYME: 3.-.-.
Caspase-4 3.4.22.58 Caspase-5 3.4.22.59 Caspase-6 3.4.22.60 Caspase-7 3.4.22.61 Caspase-8 3.4.22.62 Caspase-9 3.4.22.63 Caspase ... 4-alpha-glucosidase 3.2.1.4 Cellulase 3.2.1.5 Deleted entry 3.2.1.6 Endo-1,3(4)-beta-glucanase 3.2.1.7 Inulinase 3.2.1.8 Endo-1 ... 4-beta-xylanase 3.2.1.9 Deleted entry 3.2.1.10 Oligo-1,6-glucosidase 3.2.1.11 Dextranase 3.2.1.12 Transferred entry: 3.2.1.54 ... 4-beta-xylosidase 3.2.1.38 Beta-D-fucosidase 3.2.1.39 Glucan endo-1,3-beta-D-glucosidase 3.2.1.40 Alpha-L-rhamnosidase 3.2.1.41 ...
more infohttps://enzyme.expasy.org/EC/3.-.-.-
BIO-SYNTHESIS - Custom Antibody Custom Peptide Synthesis Custom SiRNA Synthesis: NIPSNAP3A Antibody  BIO-SYNTHESIS - Custom Antibody Custom Peptide Synthesis Custom SiRNA Synthesis: NIPSNAP3A Antibody
... elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel ...
more infohttp://bio-synthesis.blogspot.com/2011/04/nipsnap3a-antibody.html
KEGG SSDB Best Search Result: smeg:C770 GR4pD1209  KEGG SSDB Best Search Result: smeg:C770 GR4pD1209
bpec:110154344 sodium channel protein type 4 subunit al K04837 1831 112 ( 7) 31 0.313 83 ,-, 2 dat:HRM2_05270 Aor3 K03738 575 ... nca:Noca_0510 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1 K02551 537 118 ( 5) 33 0.315 130 -, 3 oas:101111152 elastin isoform X1 ... afs:AFR_01350 ABC transporter permease/ATP-binding prot K06147 566 116 ( 11) 32 0.307 176 -, 4 bsd:BLASA_4628 Glucose-methanol- ... spl:Spea_2588 Chorismate synthase K01736 364 112 ( 4) 31 0.310 100 -, 2 ssia:A7J05_08940 amino acid permease K03294 503 112 ( 7 ...
more infohttp://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=smeg:C770_GR4pD1209
Faculty Collaboration Database - Mesh term Phosphoric Monoester Hydrolases  Faculty Collaboration Database - Mesh term Phosphoric Monoester Hydrolases
4-Nitrophenylphosphatase. 6-Phytase. Acid Phosphatase. Alkaline Phosphatase. Fructose-Bisphosphatase. Glucose-6-Phosphatase. ...
more infohttps://fcd.mcw.edu/?module=search&func=showTerm&id=68010744
HMGCR ELISA & Assay Kits  HMGCR ELISA & Assay Kits
4. element-ABIN5071129. ABIN5071129. Colorimetric Plasma, Serum, Tissue Homogenate. Sandwich ELISA. 0.469 ng/mL. Log in to see ... 4-Hydroxyphenylpyruvate Dioxygenase-Like ELISA Kits * 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein ...
more infohttps://www.antibodies-online.com/ampk-signaling-pathway-15/hmgcr-elisa-kit-17140/
anti-3-Oxoacid CoA Transferase 1 Primary Antibodies  anti-3-Oxoacid CoA Transferase 1 Primary Antibodies
anti-4-Hydroxyphenylpyruvate Dioxygenase-Like Antikörper * anti-4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like ... Zusätzlich bieten wir Ihnen 3-Oxoacid CoA Transferase 1 Proteine (9) und 3-Oxoacid CoA Transferase 1 Kits (4) und viele weitere ... anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase Antikörper * anti-5-Azacytidine Induced ... anti-3-hydroxyanthranilate 3,4-Dioxygenase Antikörper * anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) ...
more infohttps://www.antikoerper-online.de/positive-regulation-of-peptide-hormone-secretion-pathway-33/oxct1-antibody-7399/
  • The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. (blogspot.com)
  • Zusätzlich bieten wir Ihnen 3-Oxoacid CoA Transferase 1 Proteine (9) und 3-Oxoacid CoA Transferase 1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. (antikoerper-online.de)
  • The preparation of 4-diphosphosphocytidyl-2C-methyl-D-erythritol 2-phosphate in multigram quantities is described for the first time. (labome.org)
  • 4. The distribution of NADPH-cytochrome c oxidoreductase demonstrated that it cannot be used in S. carlsbergensis as a specific marker enzyme for the microsomal fraction. (biochemj.org)
  • 4. Amphetamine alone had no effect on inhibitor level but amphetamine administration reduced the increase in inhibitor with high NaCl feeding. (clinsci.org)
  • An alternative transcript of HMGCS2 carrying a deletion of exon 4, and two alternative transcripts of HMGCL (zeige HMGCL Antikörper ) with deletions of exons 5 and 6, and exons 5, 6 and 7, respectively, were detected. (antikoerper-online.de)