An enzyme that catalyzes the hydrolysis of nitrophenyl phosphates to nitrophenols. At acid pH it is probably ACID PHOSPHATASE (EC 3.1.3.2); at alkaline pH it is probably ALKALINE PHOSPHATASE (EC 3.1.3.1). EC 3.1.3.41.
Yeast-like ascomycetous fungi of the family Saccharomycetaceae, order SACCHAROMYCETALES isolated from exuded tree sap.
Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.
Organized activities related to the storage, location, search, and retrieval of information.
Rare congenital X-linked disorder of lipid metabolism. Barth syndrome is transmitted in an X-linked recessive pattern. The syndrome is characterized by muscular weakness, growth retardation, DILATED CARDIOMYOPATHY, variable NEUTROPENIA, 3-methylglutaconic aciduria (type II) and decreases in mitochondrial CARDIOLIPIN level. Other biochemical and morphological mitochondrial abnormalities also exist.
A plant genus of the family CELASTRACEAE that is a source of triterpenoids and diterpene epoxides such as triptolide.
Voluntary cooperation of the patient in taking drugs or medicine as prescribed. This includes timing, dosage, and frequency.
A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Financial support of research activities.
A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.
Those individuals engaged in research.
A plant genus of the family POLYGONACEAE that is used as an EDIBLE GRAIN. Although the seeds are used as cereal, the plant is not one of the cereal grasses (POACEAE).
A specified list of terms with a fixed and unalterable meaning, and from which a selection is made when CATALOGING; ABSTRACTING AND INDEXING; or searching BOOKS; JOURNALS AS TOPIC; and other documents. The control is intended to avoid the scattering of related subjects under different headings (SUBJECT HEADINGS). The list may be altered or extended only by the publisher or issuing agency. (From Harrod's Librarians' Glossary, 7th ed, p163)
Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium.
Databases devoted to knowledge about specific genes and gene products.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
Sequential operating programs and data which instruct the functioning of a digital computer.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
Specific languages used to prepare computer programs.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
The portion of an interactive computer program that issues messages to and receives commands from a user.
Macromolecular molds for the synthesis of complementary macromolecules, as in DNA REPLICATION; GENETIC TRANSCRIPTION of DNA to RNA, and GENETIC TRANSLATION of RNA into POLYPEPTIDES.
The distinctly human attributes and attainments of a particular society.
An enzyme that catalyzes the oxidation of L-2-aminoadipate 6-semialdehyde to L-2-aminoadipate (alpha-aminoadipic acid). It is involved in the biosynthetic pathway of LYSINE.
An enzyme that catalyzes the biosynthesis of cysteine in microorganisms and plants from O-acetyl-L-serine and hydrogen sulfide. This enzyme was formerly listed as EC 4.2.99.8.
An enzyme that catalyzes the conversion of L-glutamate and water to 2-oxoglutarate and NH3 in the presence of NAD+. (From Enzyme Nomenclature, 1992) EC 1.4.1.2.
A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
A genus of ascomycetous fungi, family Sordariaceae, order SORDARIALES, comprising bread molds. They are capable of converting tryptophan to nicotinic acid and are used extensively in genetic and enzyme research. (Dorland, 27th ed)
A species of ascomycetous fungi of the family Sordariaceae, order SORDARIALES, much used in biochemical, genetic, and physiologic studies.

Hyperaldosteronemia in rabbits inhibits the cardiac sarcolemmal Na(+)-K(+) pump. (1/86)

Aldosterone upregulates the Na(+)-K(+) pump in kidney and colon, classical target organs for the hormone. An effect on pump function in the heart is not firmly established. Because the myocardium contains mineralocorticoid receptors, we examined whether aldosterone has an effect on Na(+)-K(+) pump function in cardiac myocytes. Myocytes were isolated from rabbits given aldosterone via osmotic minipumps and from controls. Electrogenic Na(+)-K(+) pump current, arising from the 3:2 Na(+):K(+) exchange ratio, was measured in single myocytes using the whole-cell patch clamp technique. Treatment with aldosterone induced a decrease in pump current measured when myocytes were dialyzed with patch pipette solution containing Na(+) in a concentration of 10 mmol/L, whereas there was no effect measured when the solution contained 80 mmol/L Na(+). Aldosterone had no effect on myocardial Na(+)-K(+) pump concentration evaluated by vanadate-facilitated [(3)H]ouabain binding or by K(+)-dependent paranitrophenylphosphatase activity in crude homogenates. Aldosterone induced an increase in intracellular Na(+) activity. The aldosterone-induced decrease in pump current and increased intracellular Na(+) were prevented by cotreatment with the mineralocorticoid receptor antagonist spironolactone. Our results indicate that hyperaldosteronemia decreases the apparent Na(+) affinity of the Na(+)-K(+) pump, whereas it has no effect on maximal pump capacity.  (+info)

Alphabeta protomers of Na+,K+-ATPase from microsomes of duck salt gland are mostly monomeric: formation of higher oligomers does not modify molecular activity. (2/86)

The distance that separates alphabeta protomers of the Na(+), K(+)-ATPase in microsomes and in purified membranes prepared from duck nasal salt glands was estimated by measuring fluorescence resonance energy transfer between anthroylouabain bound to a population of alphabeta protomers and either N-[7-nitrobenz-2-oxa-1, 3-diazol-4-yl]-6-aminohexyl ouabain or 5-(and-6)-carboxyfluorescein-6-aminohexyl ouabain bound to the rest. Energy transfer between probes bound in the microsomal preparation was less than in the purified membranes. The efficiency of energy transfer between anthroylouabain and N-[7-nitrobenz-2-oxa-1, 3-diazol-4-yl]-6-aminohexyl ouabain was 29.2% in the microsomes compared with 62.6% in the purified preparation. Similar results were obtained with 5-(and-6)-carboxyfluorescein-6-aminohexyl ouabain as acceptor. We calculate that either the protomer bound probes were on the average 13 A farther apart in the microsomes than in the purified membranes, or that 53% of the protomers are monomeric in the microsome preparation. Microsomes prepared in the presence of phalloidin (a toxin that binds to F actin and stabilizes the actin-based cytoskeleton) showed less quench than those prepared in its absence. The data support the hypothesis that protomers are kept apart by their association with the cytoskeleton. The turnover rate while hydrolyzing ATP is the same in the microsomal and purified preparations; higher oligomer formation has no significant effect on the enzyme reaction mechanism.  (+info)

HMG CoA reductase inhibition reduces sarcolemmal Na(+)-K(+) pump density. (3/86)

OBJECTIVES: HMG CoA reductase inhibitors reduce cellular availability of mevalonate, a precursor in cholesterol synthesis. Since the cholesterol content of cell membranes is an important determinant of Na(+)-K(+) pump function we speculated that treatment with HMG CoA reductase inhibitors affects Na(+)-K(+) pump activity. METHODS: We treated rabbits and rats for 2 weeks with the HMG CoA reductase inhibitor lovastatin and measured Na(+)-K(+) pump current (I(p)) in isolated rabbit cardiac myocytes using the whole cell patch-clamp technique, K-dependent p-nitrophenyl phosphatase (p-NPPase) activity in crude myocardial and skeletal muscle homogenates, and vanadate-facilitated 3H-ouabain binding in intact skeletal muscle samples from rats. RESULTS: Treatment with lovastatin caused statistically significant reductions in I(p), myocardial and skeletal muscle K-dependent p-NPPase activity and 3H-ouabain binding in the myocardium and skeletal muscle. The lovastatin-induced decrease in I(p) was eliminated by parenteral co-administration of mevalonate. However, this was not related to cardiac cholesterol content. CONCLUSIONS: Treatment with lovastatin reduces Na(+)-K(+) pump activity and abundance in rabbit and rat sarcolemma.  (+info)

Structural and immunological similarities between high molecular weight zinc ion-dependent p-nitrophenylphosphatase and fructose-1,6-bisphosphate aldolase from bovine liver. (4/86)

High molecular weight zinc ion-dependent acid p-nitrophenylphosphatase (HMW-ZnAPase) was purified from bovine liver to homogeneity as judged by native and sodium dodecyl sulfate polyacrylamide gel electrophoresis. The partial sequence of the purified enzyme electroblotted on PVDF membrane reveals a 95% sequence homology with human and bovine liver fructose-1,6-bisphosphate aldolase isozyme B (FALD B). FALD B was isolated from bovine liver using an affinity elution from phosphocellulose column. FALD B from bovine liver shows a native and subunit molecular weight that is indistinguishable from that of HMW-ZnAPase. In addition, an affinity purified antiserum raised in rabbits against purified HMW-ZnAPase cross-reacts with bovine liver FALD B and rabbit muscle isozymes. Despite these similarities, HMW-ZnAPase does not show FALD activity and bovine liver FALD does not display any zinc ion-p-nitrophenylphosphatase activity. These results suggested the existence of structural and immunological similarities between bovine liver HMW-ZnAPase and FALD B. Differences in some amino acid residues in enzyme activity indicate that they may be involved in different biochemical functions.  (+info)

p-Nitrophenylphosphatase activity catalyzed by plasma membrane (Ca(2+) + Mg(2+)ATPase: correlation with structural changes modulated by glycerol and Ca(2+). (5/86)

The plasma membrane (Ca(2+) + Mg(2+))ATPase hydrolyzes pseudo-substrates such as p-nitrophenylphosphate. Except when calmodulin is present, Ca(2+) ions inhibit the p-nitrophenylphosphatase activity. In this report it is shown that, in the presence of glycerol, Ca(2+) strongly stimulates phosphatase activity in a dose-dependent manner. The glycerol- and Ca(2+)-induced increase in activity is correlated with modifications in the spectral center of mass (average emission wavenumber) of the intrinsic fluorescence of the enzyme. It is concluded that the synergistic effect of glycerol and Ca(2+) is related to opposite long-term hydration effects on the substrate binding domain and the Ca(2+) binding domain.  (+info)

Characterization of a novel mammalian phosphatase having sequence similarity to Schizosaccharomyces pombe PHO2 and Saccharomyces cerevisiae PHO13. (6/86)

p34, a specific p-nitrophenyl phosphatase (pNPPase) was identified and purified from the murine cell line EL4 in a screen for the intracellular molecular targets of the antiinflammatory natural product parthenolide. A BLAST search analysis revealed that it has a high degree of sequence similarity to two yeast alkaline phosphatases. We have cloned, sequenced, and expressed p34 as a GST-tagged fusion protein in Escherichia coli and an EE-epitope-tagged fusion protein in mammalian cells. Using p-nitrophenyl phosphate (pNPP) as a substrate, p34 is optimally active at pH 7.6 with a K(m) of 1.36 mM and K(cat) of 0.052 min(-1). Addition of 1 mM Mg(2+) to the reaction mixture increases its activity by 14-fold. Other divalent metal ions such as Co(2+) and Mn(2+) also stimulated the activity of the enzyme, while Zn(2+), Fe(2+), and Cu(2+) had no effect. Furthermore, both NaCl and KCl enhanced the activity of the enzyme, having maximal effect at 50 and 75 mM, respectively. The enzyme is inhibited by sodium orthovanadate but not by sodium fluoride or okadaic acid. Mutational analysis data suggest that p34 belongs to the group of phosphatases characterized by the sequence motif DXDX(T/V).  (+info)

Transepithelial potential in mesonephric nephrons of 7-day-old chick embryos in relation to the histochemically detected sodium pump. (7/86)

In order to obtain basic information on the transport properties of differentiating embryonic nephrons, we examined the 7-day-old chick mesonephros by measuring the transtubular epithelial potential difference (TPD) and by histochemical detection of Na,K-ATPase activity. TPD as an indicator of the electrogenic transport was measured in individual segments of superficial nephrons in vivo. Their electric polarity was always lumen-negative. TPD was reduced by addition of 10 mM KCN applied to the mesonephric nephrons from the outside. In the proximal tubules, TPD was significantly lower (mean+/-SD: -1.0+/-0.5 mV) than in the distal and collecting tubules (-2.2+/-1.0 mV, p< or =0.05). Activity of the sodium pump was evaluated histochemically by detection of ouabain-sensitive potassium-dependent p-nitrophenyl phosphatase in cryostat sections of the mesonephros. The enzyme activity was demonstrated only in distal tubules and in the collecting ducts, but not in the proximal tubules. These findings have revealed significant differences between embryonic nephron segments: the distal tubule, in contrast to the proximal one, is supplied by the sodium pump and is able to generate higher TPD. Therefore, we consider that it is only the distal nephron, which possesses the ability of active transport.  (+info)

Cytochemistry of protein kinase C and Na-K-ATPase in rabbit ciliary processes treated with phorbol ester. (8/86)

Immunocytochemical localization of protein kinase C (PKC) in rabbit ciliary processes was investigated using anti-PKC monoclonal antibodies (MAbs) against rabbit Types 1, 2, and 3 PKC. Specific immunolabeling was observed in nonpigmented epithelial (NPE) cells and in the capillaries of the ciliary processes with anti-Types 2 and 3 MAbs. No apparent staining was seen with anti-Type 1 MAbs. Immunoelectron microscopy of Types 2 and 3 MAbs revealed a diffuse distribution of immunoreactive PKC in the cytoplasm, in the nucleus, and on the plasma membrane in the NPE cells. When incubated with phorbol 12-myristate 13-acetate (PMA), the distribution of PKC was basically similar to that of the untreated group. However, the labelling density on the plasma membrane at basolateral interdigitation increased considerably for anti-Types 2 and 3 PKC MAbs. In addition, the enzyme cytochemical activity of Na-K-ATPase (ouabain-sensitive K-NPPase) and its change after PMA administration in the ciliary processes were observed. An intense reaction was seen on the basolateral plasma membrane of the NPE cells. In the PMA-treated group, the enzyme activity of Na-K-ATPase apparently was decreased. These findings provide evidence that PKC plays a crucial role in the function of the NPE cells of the ciliary processes, possibly in aqueous humor production.  (+info)

1. These experiments examined the effects of a high NaCl diet on (Na+, K+)-ATPase in kidney, heart and cerebral cortex, on the level of circulating inhibitor of (Na+, K+)-ATPase in plasma, and on stimulation of (Na+, K+)-ATPase by treatment with dextro (d)-amphetamine.. 2. High salt diet increased indices of (Na+, K+)-ATPase activity (K+-activated p-nitrophenylphosphatase activity and ouabain binding) in kidney medulla, prevented stimulation by amphetamine in cerebral cortex and reduced amphetamine stimulation in heart.. 3. High NaCl feeding increased the plasma level of circulating inhibitor of (Na+, K+)-ATPase.. 4. Amphetamine alone had no effect on inhibitor level but amphetamine administration reduced the increase in inhibitor with high NaCl feeding.. ...
The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. While NIPSNAP3B is highly expressed skeletal muscle, NIPSNAP3A mRNA levels are low. NIPSNAP3A protein is associated with plasma membrane and partially localized in rafts. NIPSNAP proteins have been suggested to be important in vesicular transport. At least two isoforms of NIPSNAP3A are known to exist. NIPSNAP3A antibody is predicted to not cross-react with any other members of the NIPSNAP protein family. ...
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Story includes research items about: centronuclear myopathy; Duchenne, limb-girdle, and Emery-Dreifuss muscular dystrophies; and spinal muscular atrophy.Missing or reduced levels of an enzyme known as neuronal nitric oxide synthase (nNOS) at its normal location on muscle-fiber membranes prevents blood vessels that supply active muscles from relaxing normally, leading to exercise-associated fatigue, says a team of researchers from the University of Iowa in Iowa City, the University of Michigan in Ann Arbor, and the University of Washington School of Medicine in Seattle.. Read More ...
Crimson blood cells from mink ( em Mustela vison /em ) were characterized regarding their electrolyte content material and their cell membranes regarding enzymatic activity for cation transport. an inside-negative membrane potential in mink erythrocytes. Regardless of a steep calcium mineral gradient over the crimson cell membrane, neither a calmodulin-activated Ca2+-ATPase activity nor an ATP-activated Ca2+-pNPPase activity had been detectable in the plasma membrane small percentage. The origin of the supposed principal Ca2+ gradient for sustaining of osmotic stability thus appears uncertain. strong course=kwd-title Keywords: erythrocytes, plasma, electrolytes, crimson cell, mink crimson cells, Na+,K+-ATPase, membrane potential, osmotic stability, PM-CaATPase Launch The plasma membrane-embedded (Na++K+)-turned on ATPase (Na,K-ATPase, EC 3.6.1.37) of mammalian cells is normally supposed to have got an essential function in counterbalancing passive ionic leakages and oncotic pushes from ...
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1. Homogenates were prepared from sphaeroplasts of aerobically grown glucose-de-repressed Saccharomyces carlsbergensis and the distributions of marker enzymes were investigated after differential centrifugation. Cytochrome c oxidase and cytochrome c were sedimented almost completely at 105g-min, and this fraction also contained 37% of the catalase, 27% of the acid p-nitrophenyl phosphatase, 53 and 54% respectively of the NADH- and NADPH-cytochrome c oxidoreductases. 2. Zonal centrifugation indicated complex density distributions of the sedimentable portions of these enzymes and of adenosine triphosphatases and suggested the presence of two mitochondrial populations, as well as a bimodal distribution of peroxisomes and heterogeneity of the acid p-nitrophenyl phosphatase-containing particles. 3. Several different adenosine triphosphatases were distinguished in a post-mitochondrial supernatant that contained no mitochondrial fragments; these enzymes varied in their sensitivities to oligomycin and ...
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BioAssay record AID 88393 submitted by ChEMBL: In vitro inhibition of Hematopoietic protein-tyrosine phosphatase using p-nitrophenyl phosphate as substrate..
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Quite right, Donnachadh. And in those days everyone smelt like a decomposing kipper and I doubt very much if LOreal shifted a whole lot of product either. Why do these soap-dodging greenies want to take us back to being neanderthal cave dwellers? I wonder if they really fancy the whole authentic experience. How about a world with no antibiotics or anaesthetics? There you are, in your cave, nibbling on an old bit of tofu, shivering in the freezing cold and youve got a raging toothache and a streptococcal infection that could scare the shit out of vancomycin. As you lay there in absolute agony, all you can smell is the fetid armpits of Ugg sat next to you. Is that the sort of world these people really want us to live in? It cant be long before they call for mandatory limits on the number of showers we can take ...
Distinguish between (i) Peptic and oxyntic cells (ii) Lipases and peptidases (///) Villi and microvilli (iv) Sucrose and maltose (v) Extracellular and intracellular digestion.
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Researchers at the Stanford Human Genome Center have developed a powerful new computer program that can map thousands of genetic markers at once. Using this program, called Mapper, scientists have obtained one of the most accurate views yet of the humangenome as a whole.
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ENDOTOXINE (TOXIKOLOGIE); BACILLUS THURINGIENSIS (MIKROBIOLOGIE); IN-VITRO UNTERSUCHUNGEN (TOXIKOLOGIE); ENDOTOXINS (TOXICOLOGY); BACILLUS THURINGIENSIS (MICROBIOLOGY); IN VITRO STUDIES (TOXICOLOGY ...
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They fused the sequence for Bt toxin Cry1Ac with that of the nontoxic B-chain subunit of ricin (RB) in a recombinant plasmid. RB is a leptin that binds with galactose as well as N-acetylgalactosamine residues with high affinity, the latter of which are key components of Bt toxin-binding receptors. Then embryonic callus from mature maize seeds were bombarded with this BtRB fusion. The researchers tested their fusion toxin against stem borer Chilo suppressalis, a pest normally susceptible to Cry1Ac, and found that maize producing low levels of BtRB killed 75 per cent of larvae, compared with 17 per cent in Bt-only plants. Similar trials with the cotton leaf worm Spodoptera littoralis, which is resistant to Bt delta endotoxins, showed that after 4 days, nearly 78 per cent of larvae died on BtRB maize, compared with less than 20 per cent on Bt-only or nontransformed maize. In the leafhopper Cicadulina mbila, which like other homopterans was ordinarily not affected by Bt toxins, 95 per cent of ...
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1963 Porsche 356 Coupe. The T-6 body style spanned the 356 B and the 1964 model year 356 C. There is only one visible exterior difference between the 356 C...
Bullfrog tadpole stomachs of various metamorphic stages were examined to determine the fine-structural development of oxyntic cells and to correlate observed morphological development with the capacity to secrete HCl. It was found that in vitro tadpole stomachs can consistently be stimulated to secrete acid by stage XXIV of metamorphosis, when tail reabsorption is nearly complete. Concomitant with the appearance of HCl secretion, identifiable oxyntic cells were found in the gastric glands.. Prior to stage XXIV (stages XXI and XXII) the majority of cells present in the developing gastric glands exhibit features of cytological organization characteristic of undifferentiated cells: large nuclei, relatively scantry cytoplasm, and numerous ribosomal particles within the cytoplasmic matrix. The newly differentiated oxyntic cells of stage XXIV tadpole stomachs are recognizable by the accumulation of tubular members of the smooth-surfaced endoplasmic reticulum in the apical portion of the cells. These ...
2-(p-Nitrophenyl)adenine | C11H8N6O2 | CID 5486769 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
AP is purified from calf intestine by affinity chromatography. AP is an important label in enzyme immuno assays for substrates like pNPP and BCIP
Thioglycosides have proved to be useful, enzymatically stable analogs of glycosides for structural and mechanistic studies and their synthesis is considerably simplified through the use of thioglycoligases. As part of an investigation into the use of thioglycosides as potential pharmacological chaperones, and as components of glycoproteins and glycolipids, the syntheses of p-nitrophenyl 3-thio-β-D-galactopyranoside, phenyl 1,4-dithio-β-D-glucopyranoside, p-nitrophenyl 4-thio-β-D-mannopyranoside and p-nitrophenyl 2-acetamido-2-deoxy-4-thio-β-D-mannopyranoside are described.
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TY - JOUR. T1 - Cloning, Expression, and Catalytic Mechanism of the Low Molecular Weight Phosphotyrosyl Protein Phosphatase from Bovine Heart. AU - Wo, Yu Yuan P.. AU - Zhou, Ming Ming. AU - Stevis, Panayiotis. AU - Davis, June P.. AU - Zhang, Zhong Yin. AU - Van Etten, Robert L.. PY - 1992/2/1. Y1 - 1992/2/1. N2 - The first representative of a group of mammalian, low molecular weight phosphotyrosyl protein phosphatases was cloned, sequenced and expressed in Escherichia coli. Using a 61-mer oligonucleotide probe based on the amino acid sequence of the purified enzyme, several overlapping cDNA clones were isolated from a bovine heart cDNA library. A full-length clone was obtained consisting of a 27-bp 5ʹ3ʹ noncoding region, an open reading frame encoding the expected 157 amino acid protein, and an extensive 3 nontranslated sequence. The identification of the clone as full length was consistent with results obtained in mRNA blotting experiments using poly(A)+ mRNA from bovine heart. The coding ...
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4-beta-glucosidase MeSH D08.811.277.450.420.200.600 - glucan endo-1,3-beta-d-glucosidase MeSH D08.811.277.450.420.375 - glucan ... map kinase kinase 4 MeSH D08.811.913.696.620.682.700.565.500 - map kinase kinase 5 MeSH D08.811.913.696.620.682.700.565.600 - ... map kinase kinase 4 MeSH D08.811.913.696.620.682.725.200.500 - map kinase kinase 5 MeSH D08.811.913.696.620.682.725.200.600 - ... type 4 MeSH D08.811.913.696.620.682.725.400.050 - proto-oncogene proteins c-kit MeSH D08.811.913.696.620.682.725.400.075 - ...
EC 3.2.1.91: cellulose 1,4-b-cellobiosidase EC 3.2.1.92: peptidoglycan b-N-acetylmuramidase EC 3.2.1.93: a,a-phosphotrehalase ... 4-b-xylosidase EC 3.2.1.38: b-D-fucosidase EC 3.2.1.39: glucan endo-1,3-b-D-glucosidase EC 3.2.1.40: a-L-rhamnosidase EC 3.2. ... 4-a-glucosidase EC 3.2.1.4: cellulase EC 3.2.1.5: deleted EC 3.2.1.6: endo-1,3(4)-b-glucanase EC 3.2.1.7: inulinase EC 3.2.1.8 ... 4-b-xylanase EC 3.2.1.137: mannan exo-1,2-1,6-a-mannosidase EC 3.2.1.138: now EC 4.2.2.15 EC 3.2.1.139: Alpha-glucuronidase EC ...
Other names in common use include nitrophenyl phosphatase, p-nitrophenylphosphatase, para-nitrophenyl phosphatase, K-pNPPase, ... Attias J, Bonnet JL (1972). "A specific alkaline p-nitrophenylphosphatase activity from baker's yeast". Biochim. Biophys. Acta ... Attias J, Durand H (1973). "Further characterization of a specific p-nitrophenylphosphatase from baker's yeast". Biochim. ... NPPase, PNPPase, Ecto-p-nitrophenyl phosphatase, and p-nitrophenylphosphate phosphohydrolase. This enzyme participates in gamma ...
NIPSNAP14-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1; Numb: Drosophila mutation that removes ... 1773 (4): 565-76. doi:10.1016/j.bbamcr.2007.01.001. PMID 17292493. Zhang SS, Xie X, Wen J, Luo KJ, Liu QW, Yang H, et al. ( ... 78 (4): 274-82. doi:10.1002/mrd.21303. PMID 21400627. S2CID 21140465. De Clercq K, Van den Eynde C, Hennes A, Van Bree R, Voets ... 57 (4): 427-50. doi:10.1124/pr.57.4.6. PMID 16382100. S2CID 17936350. Müller D, Hoenderop JG, Merkx GF, van Os CH, Bindels RJ ( ...
Other names in common use include nitrophenyl phosphatase, p-nitrophenylphosphatase, para-nitrophenyl phosphatase, K-pNPPase, ... Attias J, Bonnet JL (1972). "A specific alkaline p-nitrophenylphosphatase activity from bakers yeast". Biochim. Biophys. Acta ... Attias J, Durand H (1973). "Further characterization of a specific p-nitrophenylphosphatase from bakers yeast". Biochim. ... NPPase, PNPPase, Ecto-p-nitrophenyl phosphatase, and p-nitrophenylphosphate phosphohydrolase. This enzyme participates in gamma ...
Recombinant 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (C. Elegans) (NIPSNAP1) Protéine. ... 4 °C/-20 °C/-80 °C. * Détail du antigène (hide) Nom de la protéine. 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25- ... 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (C. Elegans) (NIPSNAP1) Type de proteíne. ... 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (C. Elegans) (NIPSNAP1) Protéine Protein ...
Recombinant 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (C. Elegans) (NIPSNAP1) Protéine ( ... 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (C. Elegans) (NIPSNAP1) Sujet. Full Gene Name: ... 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (C. Elegans) (NIPSNAP1) Type de proteíne. ... 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (C. Elegans) (NIPSNAP1) (AA 1-284) protein (GST ...
4-nitrophenylphosphatase. An enzyme that catalyzes the hydrolysis of nitrophenyl phosphates to nitrophenols. At acid pH it is ...
3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 3.1.3.87 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate ... 5775 PTPN4; protein tyrosine phosphatase non-receptor type 4 5780 PTPN9; protein tyrosine phosphatase non-receptor type 9 26095 ... 2070 EYA4; EYA transcriptional coactivator and phosphatase 4 84867 PTPN5; protein tyrosine phosphatase non-receptor type 5 5778 ... 1846 DUSP4; dual specificity phosphatase 4 1844 DUSP2; dual specificity phosphatase 2 1849 DUSP7; dual specificity phosphatase ...
... 26 4-phytase. EC 3.1.3.27 phosphatidylglycerophosphatase. EC 3.1.3.28 ADPphosphoglycerate phosphatase. EC 3.1.3.29 N- ... EC 3.1.3.40 guanidinodeoxy-scyllo-inositol-4-phosphatase. EC 3.1.3.41 4-nitrophenylphosphatase. EC 3.1.3.42 [glycogen-synthase- ... EC 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. EC 3.1.3.68 2-deoxyglucose-6-phosphatase. EC 3.1.3.69 ... EC 3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase. EC 3.1.3.58 sugar-terminal-phosphatase. EC 3.1.3.59 ...
EC 3.1.4: Phosphoric Diester Hydrolases. * EC 3.1.4.1: phosphodiesterase I * EC 3.1.4.2: glycerophosphocholine ... EC 3.1.3.66: phosphatidylinositol-3,4-bisphosphate 4-phosphatase * EC 3.1.3.67: phosphatidylinositol-3,4,5-trisphosphate 3- ... EC 3.2.1.141: [[4-a-D-((1(arrow to right)4)-a-D-glucano}trehalose trehalohydrolase]] ... EC 3.1.1.66: 5-(3,4-diacetoxybut-1-ynyl)-2,2-bithiophene deacetylase ...
1 3 4 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ... NF2 lnc-NEFH-1 lnc-NIPSNAP1-4 EWSR1 SF3A1 THOC5 NIPSNAP1 UQCR10 ... 1) SIMAP similar genes for NIPSNAP1 Gene using alignment to 4 proteins:. *NIPS1_HUMAN ... Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin ...
3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 3.1.3.87 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate ...
Proteinase K cleavage.Pig kidney membranes were incubated in 25/or 1 mM ADP, as indicated. The samples were treated with PK (PK/protein ratio ∼1∶50) and the
Effect of temperature, pH, and vanadate sensitivity of the CPZ treated enzyme.A. Pig kidney Na+,K+-ATPase activity was measured at four different temperatures,
cfi:Celf_0823 PHP domain protein K04477 240 110 ( 7) 31 0.321 112 -, 4 cro:ROD_25061 N-acetylmuramic acid 6-phosphate etherase ... aly:ARALYDRAFT_475563 large subunit of riblose-1,5-bisp K01601 479 375 ( 0) 91 0.266 410 -, 4 apak:AP3564_01620 2,3-diketo-5- ... srw:TUE45_02259 putative hydrolase YutF 342 122 ( 4) 34 0.318 195 -, 6 cfl:Cfla_2467 UBA/THIF-type NAD/FAD binding protein 497 ... psos:POS17_0309 dTDP-4-dehydrorhamnose reductase K00067 293 106 ( 3) 30 0.325 83 -, 2 saq:Sare_3653 aldo/keto reductase K05275 ...
4-nitrophenylphosphatase activity; ATP binding; ATPase activity, coupled to transmembrane movement of ions, phosphorylative ...
4-beta-glucosidase MeSH D08.811.277.450.420.200.600 - glucan endo-1,3-beta-d-glucosidase MeSH D08.811.277.450.420.375 - glucan ... map kinase kinase 4 MeSH D08.811.913.696.620.682.700.565.500 - map kinase kinase 5 MeSH D08.811.913.696.620.682.700.565.600 - ... map kinase kinase 4 MeSH D08.811.913.696.620.682.725.200.500 - map kinase kinase 5 MeSH D08.811.913.696.620.682.725.200.600 - ... type 4 MeSH D08.811.913.696.620.682.725.400.050 - proto-oncogene proteins c-kit MeSH D08.811.913.696.620.682.725.400.075 - ...
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1. 33. 24. 9.5. 8.4. 12 /14. 23. 26. NIPSNAP1. AJ001258. np. np. − ...
Powered by Pure, Scopus & Elsevier Fingerprint Engine™ © 2020 Elsevier B.V "We use cookies to help provide and enhance our service and tailor content. By continuing you agree to the use of cookies. Log in to Pure. ...
4. 59. Arachidonic acid metabolism (KEGG):00590. 7.13397324646485e-08. 4.51580506501225e-05. 4. 30. Linoleic acid metabolism ( ... 4. 289. Metabolism of lipids and lipoproteins (Reactome):REACT_22258. 0.000692868648311646. 0.0292390569587515. 3. 130. ... 4-hydroxyacetophenone monooxygenase activity. 0.020781869242664. GO:0015788. UDP-N-acetylglucosamine transport. ...
para Nitrophenyl Phosphatase para Nitrophenylphosphatase para-Nitrophenyl Phosphatase para-Nitrophenylphosphatase K-p NPPase - ... para Nitrophenyl Phosphatase. para Nitrophenylphosphatase. para-Nitrophenyl Phosphatase. para-Nitrophenylphosphatase. Tree ... Nitrophenyl Phosphatase. p NPPase. p Nitrophenylphosphatase. p-NPPase. p-Nitrophenylphosphatase. p-Nitrophenylphosphatase, K- ... K-Dependent p-Nitrophenylphosphatase p-Nitrophenylphosphatase, K-Dependent Nitrophenyl Phosphatase - Broader Concept UI. ...
Ontogeny of lactate dehydrogenase, acetyl cholinesterase, K+-stimulated p-nitrophenyl phosphatase & (Na+ + K+)ATPase in human ... 4-Nitrophenylphosphatase/metabolism , Acetylcholinesterase/metabolism , Female , Humans , L-Lactate Dehydrogenase/metabolism , ... 4-Nitrophenylphosphatase / Phosphoric Monoester Hydrolases / L-Lactate Dehydrogenase Language: English Journal: Indian J ... 4-Nitrophenylphosphatase / Phosphoric Monoester Hydrolases / L-Lactate Dehydrogenase Language: English Journal: Indian J ...
PFB0310c (MSP-4, MSP4) merozoite surface protein 4 *PFD1160w (SURFIN4.2, Surf4.2) surface-associated interspersed gene 4.2, ( ... PFD1120c (ETRAMP4, SEP4, Etramp 4, Etramp4) early transcribed membrane protein 4 *PF11_0302 (PV-1) parasitophorous vacuolar ... PFD1120c (ETRAMP4, SEP4, Etramp 4, Etramp4) early transcribed membrane protein 4 *PFD0310w (Pfs16) sexual stage-specific ... PFC0105w (SRPK1, CLK-4) serine/threonine protein kinase, putative *PFI0250c (Nup100) conserved Plasmodium membrane protein, ...
... p-nitrophenyl phosphatase (K+ pNPPase) were studied in the liver and kidney as histopathological biomarkers, to assess the ... and K+ p-nitrophenyl phosphatase (K+ pNPPase) were studied in the liver and kidney as histopathological biomarkers, to assess ... and K+ p-nitrophenyl phosphatase (K+ pNPPase) were studied in the liver and kidney as histopathological biomarkers, to assess ... and K+ p-nitrophenyl phosphatase (K+ pNPPase) were studied in the liver and kidney as histopathological biomarkers, to assess ...
Caspase-4 3.4.22.58 Caspase-5 3.4.22.59 Caspase-6 3.4.22.60 Caspase-7 3.4.22.61 Caspase-8 3.4.22.62 Caspase-9 3.4.22.63 Caspase ... 4-alpha-glucosidase 3.2.1.4 Cellulase 3.2.1.5 Deleted entry 3.2.1.6 Endo-1,3(4)-beta-glucanase 3.2.1.7 Inulinase 3.2.1.8 Endo-1 ... 4-beta-xylanase 3.2.1.9 Deleted entry 3.2.1.10 Oligo-1,6-glucosidase 3.2.1.11 Dextranase 3.2.1.12 Transferred entry: 3.2.1.54 ... 4-beta-xylosidase 3.2.1.38 Beta-D-fucosidase 3.2.1.39 Glucan endo-1,3-beta-D-glucosidase 3.2.1.40 Alpha-L-rhamnosidase 3.2.1.41 ...
1.3.4. Some insights into the development of the Drosophila NMJ 9 13 1.4. Work leading on to this project 14 1.5. Objectives of ... 3.4.4 Synaptic phenotype of eIF4AIII is suppressed in dlg mutant background 72 3.5 Analysis of cG4699/waharan 73 Index IV 3.5.1 ... 4.4.4. Potential genetic interactions of wah 119. Summary 123. Appendix I 125. 6.1 Different strategies to generate probes for ... 2.1.4 Embryo collection 17 2.1.5 Balancing the mutant stocks over green-balancer 17 2.1.6 Whole mount embryo preparation for in ...
Shah RL, Li Q, Zhao W, Tedja MS, Tideman JWL, Khawaja AP, Fan Q, Yazar S, Williams KM, Verhoeven VJM, Xie J, Wang YX, Hess M, Nickels S, Lackner KJ, Pärssinen O, Wedenoja J, Biino G, Concas MP, Uitterlinden A, Rivadeneira F, Jaddoe VWV, Hysi PG, Sim X, Tan N, Tham YC, Sensaki S, Hofman A, Vingerling JR, Jonas JB, Mitchell P, Hammond CJ, Höhn R, Baird PN, Wong TY, Cheng CY, Teo YY, Mackey DA, Williams C, Saw SM, Klaver CCW, Guggenheim JA, Bailey-Wilson JE. A genome-wide association study of corneal astigmatism: The CREAM Consortium. Mol Vis. 2018; 24:127-142 ...
4. Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard. ... Crystal structure of 4-nitrophenylphosphatase (TM1742) from Thermotoga maritima at 2.40 A resolution. To be published. ... The gene TM1742 from Thermotoga maritima encodes a 4-nitrophenylphosphatase EC:3.1.3.41. The enzyme was previously crystallized ... The enzyme catalyzes the hydrolysis of 4-nitrophenyl phosphate to form 4-nitrophenol. ...
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group). 0.193. ... pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2. 0.111. ... 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans). 0.028. ... solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4. 0.029. ...
4-lactone oxidase, involved in biosynthesis of D-erythroascorbic acid, which has a protective role against oxidative damage; ... 4-Dihydroxy-2-butanone 4-phosphate synthase; homodimeric enzyme of riboflavin biosynthesis; converts ribulose 5-phosphate to L- ... 3,4-dihydroxy-2-butanone 4-phosphate; transcription regulated on yeast-hypha switch; macrophage interaction Inositol phosphoryl ... Gcn4p-regulatedProtein abundance is affected by URA3 expression in the CAI-4 strain background; alkaline upregulated; Gcn4p- ...
4. Starvation 05/01/2013 - "Taken together this study provides evidence for mycorrhizal alkaline phosphatases playing a role in ... Campylobacter jejuni UDP-2,4-diacetamido-2,4,6-trideoxy-L-altrose hydrolase ...
X-ray diffraction data for the Crystal structure of a putative monooxygenase (YP_001095275.1) from Shewanella loihica PV-4 at ... X-ray diffraction data for the Crystal structure of 4-nitrophenylphosphatase (TM1742) from Thermotoga maritima at 2.40 A ...
  • We employed a modification of our previously reported cerium-based cytochemical method for ouabain-sensitive, K-dependent p-nitrophenylphosphatase (Na-K ATPase) activity to detect ouabain-insensitive, K-stimulated p-nitrophenylphosphatase (K-pNPPase) activity in rat gastric glands. (bocsci.com)
  • 4.The effect of ionic strength and specific anions on substrate binding and hydrolytic activities of Na,K-ATPase. (bocsci.com)
  • 2. High salt diet increased indices of (Na + , K + )-ATPase activity (K + -activated p -nitrophenylphosphatase activity and ouabain binding) in kidney medulla, prevented stimulation by amphetamine in cerebral cortex and reduced amphetamine stimulation in heart. (clinsci.org)
  • However, K(+)-phosphatase activity was not stimulated further by K(+) plus NH(4) (+) ions. (bocsci.com)
  • Surprisingly, as the Sulfolobus enzyme, the Human and Pseudomonas proteins display poly(ADP-ribose) polymerase activity, whereas a phosphatase activity was only present in [ncbi.nlm.nih.gov] The protein exhibited high esterase activity towards short chain esters like ethyl acetate and 4- nitrophenyl acetate. (symptoma.com)
  • A lipid phosphatase that acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. (rush.edu)
  • In enzymology, a 4-nitrophenylphosphatase (EC 3.1.3.41) is an enzyme that catalyzes the chemical reaction 4-nitrophenyl phosphate + H2O ⇌ {\displaystyle \rightleftharpoons } 4-nitrophenol + phosphate Thus, the two substrates of this enzyme are 4-nitrophenyl phosphate and H2O, whereas its two products are 4-nitrophenol and phosphate. (wikipedia.org)
  • Catalase was found exclusively in the supernatant fraction whilst NADH: cytochrome c oxidoreductase and p -nitrophenylphosphatase were found in all the fractions. (microbiologyresearch.org)
  • 4. The distribution of NADPH-cytochrome c oxidoreductase demonstrated that it cannot be used in S. carlsbergensis as a specific marker enzyme for the microsomal fraction. (biochemj.org)
  • M 3 mAChRs trigger similar signal transduction pathways that involve the heterotrimeric G protein Gq-mediated activation of phospholipase C (PLC) - β , which results in the generation of inositol 1,4,5-trisphosphate (IP 3 ) and 1,2-diacylglycerol (DAG). (aspetjournals.org)
  • The p-nitrophenylphosphatase and inorganic pyrophosphatase activities were inhibited, while 40% of the ATP-splitting enzyme activity remained under the assay condition used. (meta.org)
  • Using this principle, we constructed mesoporous structures on the surfaces of pure platinum electrodes responding even more sensitively to glucose than to common interfering species, such as L-ascorbic acid and 4-acetamidophenol. (biomedsearch.com)
  • A calmodulin kinase II inhibitor [(8)-5-isoquinolinesulfonic acid, 4-[2-(5-isoquinolinyl-sulfonyl)methylamino]-3-oxo-(4-phenyl-1-piperazinyl)-propyl]phenyl ester (KN-62)] decreased the pilocarpine-induced increase of AQP5 in the APM. (aspetjournals.org)
  • I. Properties and distribution of heat- and formaldehyde-stable liver acid p-nitrophenylphosphatase. (naver.com)
  • Changes in tissue and plasma heat- and formaldehyde-stable acid p-nitrophenylphosphatase. (naver.com)
  • Two new molecules (1E,3E)-1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene (1-Naph-DNB) and (2Z,4E)-2-methylsulfanyl-5-(1-naphthyl)-4-nitro-2,4- pentadienoate (1-Naph-NMCB) in previous studies showed interesting antiproliferative activity in vitro. (elsevier.com)
  • 2.Detection of ouabain-insensitive H(+)-transporting, K(+)-stimulated p-nitrophenylphosphatase activity in rat gastric glands by cerium-based cytochemistry. (bocsci.com)
  • Separation of large lysosomal vacuoles which contained p -nitrophenylphosphatase activity was obtained and these were clearly resolved from mitochondria by both highspeed and rate zonal centrifugation. (microbiologyresearch.org)
  • The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. (blogspot.com)
  • Effects of lead and a low-molecular-weight endogenous plasma inhibitor on the kinetics of sodium-potassium-activated adenosine triphosphatase and potassium-activated p-nitrophenylphosphatase. (semanticscholar.org)
  • The systematic name of this enzyme class is 4-nitrophenylphosphate phosphohydrolase. (wikipedia.org)
  • The preparation of 4-diphosphosphocytidyl-2C-methyl-D-erythritol 2-phosphate in multigram quantities is described for the first time. (labome.org)
  • The effect of the herbicide diclofop-methyl (methyl 2-[4-(2',4'-dichlorophenoxy)phenoxy]propanate) on physiological activities and on cell constituents of root tips isolated from untreated and herbicide treated seedlings of Z. mays was studied. (eurekamag.com)
  • Pretreatment of rat parotid tissue with the NO scavenger 2-(4carboxyphenyl)-4,4,5,5-tetramethyl-imidazoline-1-oxyl-3-oxide potassium inhibited both acetylcholine (ACh)- and pilocarpine-induced increases in AQP5 in the APM. (aspetjournals.org)
  • 4. Amphetamine alone had no effect on inhibitor level but amphetamine administration reduced the increase in inhibitor with high NaCl feeding. (clinsci.org)
  • Functional effects of caloxin 1c2, a novel engineered selective inhibitor of plasma membrane Ca(2+)-pump isoform 4, on coronary artery. (mcmaster.ca)
  • Pretreatment of the tissues with a myosin light chain kinase inhibitor [(5-chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine (ML-9)] inhibited a mAChR-stimulated increase in AQP5 levels in the APM. (aspetjournals.org)
  • Zusätzlich bieten wir Ihnen 3-Oxoacid CoA Transferase 1 Proteine (9) und 3-Oxoacid CoA Transferase 1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. (antikoerper-online.de)
  • Mitochondria were sedimented quantitatively at 10 4 g -min and accounted for approximately 10% of the total recovered protein. (microbiologyresearch.org)
  • UBXD8 (显示 FAF2 ELISA试剂盒 ) is necessary for sterol-stimulated dislocation of ubiquitylated HMGCR from the endoplasmic reticulum membrane en route to proteasomal degradation, a function dependent on its UBX domain. (antibodies-online.cn)
  • The electron transfer system catalysing reduction of fumarate by NADH under anaerobic conditions in membrane preparations of Bacteroides ruminicola strain B 1 4 was inhibited by 2-n-heptyl-4-hydroxyquinoline N -oxide. (microbiologyresearch.org)
  • In reconstructing the exposure, the author concluded that the lowest adverse effect level was approximately 5.3 mg in 3/4 fluid ounces or 10.65 mg of copper. (nih.gov)
  • Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. (meta.org)
  • Reduction of b -type cytochrome by NADH under anaerobic conditions was much slower than reduction of fumarate by NADH, and was more sensitive to 2-n-heptyl-4-hydroxyquinoline N -oxide inhibition. (microbiologyresearch.org)
  • Extraction of quinone from the membrane and subsequent reincorporation showed that menaquinone (vitamin K 2 ) is an obligatory intermediate in the reduction of both fumarate and b -type cytochrome by NADH, which is consistent with the 2-n-heptyl-4-hydroxyquinoline N -oxide inhibition results. (microbiologyresearch.org)
  • Renal and vascular effects of C-type and atrial natriuretic peptides in humans," American Journal of Physiology-Regulatory Integrative and Comparative Physiology , vol. 273, no. 4, pp. (hindawi.com)
  • Official investigations had revealed that 1.3 % of adults in Guadeloupe were exposed above the "no effect threshold dose" (the reference dose RfD) of 0.5 μg/kg/d [ 4 ]. (biomedcentral.com)
  • Our pilot study aimed to determine the effect of gestational lifestyle counseling on the offspring weight gain until 4 year. (biomedcentral.com)
  • An alternative transcript of HMGCS2 carrying a deletion of exon 4, and two alternative transcripts of HMGCL (zeige HMGCL Antikörper ) with deletions of exons 5 and 6, and exons 5, 6 and 7, respectively, were detected. (antikoerper-online.de)