4-Aminobenzoic Acid
meta-Aminobenzoates
ortho-Aminobenzoates
Aminobenzoates
Peroxidase
N-acetylation of the heterocyclic amine batracylin by human liver. (1/255)
Batracylin (8-aminoisoindolo[1,2-b]quinazolin-12(10 H)-one; BAT) is a heterocyclic amine that exhibits antitumor activity in a number of in vivo and in vitro models. The acetyl product has been implicated in BAT toxicity in animals, cells, and bacteria. The ability of human N-acetyltransferase (NAT) to form this product was investigated. Nine human liver samples were analyzed for NAT1 and NAT2 genotypes. Seven of the samples possessed at least one NAT1*4 allele. Three samples contained one or more NAT2*4 allele and were classified as rapid acetylators. The remaining six had two alleles associated with the slow phenotype. NAT activities were evaluated with BAT, sulfamethazine (SMZ), a preferential substrate for human NAT2, and p-aminobenzoic acid, a substrate for NAT1. BAT activities in the nine donor samples ranged from 14.9 to 0.56 nmol/min/mg. The mean apparent K(m) values in rapid acetylators for BAT, SMZ, and p-aminobenzoic acid were 6.59 +/- 3.21, 278 +/- 69.4, and 31.2 +/- 12.5 microM, respectively. The apparent K(m) values for slow acetylators did not differ from the rapid acetylator phenotype. However, a significant difference in the apparent V(max) for BAT and SMZ was observed between rapid and slow acetylators. Comparing the apparent intrinsic clearance (V(max)/K(m)) for BAT and SMZ, a significant correlation (r(2) = 0.97, p <.001) was observed. These data demonstrate that BAT N-acetylation is similar to SMZ, and suggests that BAT is a preferential substrate for human NAT2. Thus, rapid acetylators would be more likely to develop toxicity when exposed to this drug. (+info)Antagonism of 5-hydroxytryptamine(4) receptors attenuates hyperactivity induced by cocaine: putative role for 5-hydroxytryptamine(4) receptors in the nucleus accumbens shell. (2/255)
The localization of 5-hydroxytryptamine(4) (5-HT(4)) receptors suggests their role in the regulation of dopamine (DA) neurotransmission, a speculation that has been supported by neurochemical studies. Mesolimbic DA systems play a prominent role in mediating the behavioral effects of the abused psychostimulant cocaine, and the intent of the present study was to assess the role of 5-HT(4) receptors in the control of spontaneous and cocaine-induced activity. Systemic administration of the 5-HT(4) receptor partial agonist 1-(4-amino-5-chloro-2-methoxyphenyl)-3-[1-butyl-4-piperidinyl]1-propa none hydrochloride (RS 67333; 0.0001-1 mg/kg) or the 5-HT(4) receptor antagonist 4-amino-5-chloro-2-methoxy-benzoic acid-(diethylamino)ethyl ester hydrochloride (SDZ 205,557; 0.0001-1 mg/kg) did not significantly alter spontaneous activity, whereas SDZ 205,557 significantly attenuated cocaine-induced horizontal activity and rearing. To test the hypothesis that cocaine-elicited behaviors were modulated by 5-HT(4) receptors in the nucleus accumbens (NAc) shell, two separate groups of male rats were implanted with bilateral cannulas aimed at the NAc shell. Intra-NAc shell microinjections of either RS 67333 (1 or 3 microgram/0.2 microliter/side) or SDZ 205,557 (1-5 microgram/0.2 microliter/side) did not alter spontaneous activity observed after a systemic saline injection but did significantly attenuate the hyperactivity induced by systemic cocaine injection (10 mg/kg). These results support an involvement of 5-HT(4) receptors, particularly those in the NAc shell, in the locomotor stimulatory effects of cocaine. Furthermore, these data suggest that 5-HT(4) receptors may regulate behavioral processes dependent on mesolimbic DA pathways and may provide a novel target for the development of medications useful in the treatment of both drug dependence and psychiatric disorders. (+info)Increased levels of dihydrofolate reductase in rifampin-resistant mutants of Bacillus subtilis. (3/255)
Several independent, spontaneous rifampin-resistant mutants of Bacillus subtilis were isolated and found to have an increased resistance to trimethoprim, an inhibitor of dihydrofolate reductase. This increased resistance in the rif mutants was the result of a specific threefold increase in the activity of dihydrofolate reductase, since six other enzymes examined remained unchanged. This increased level of dihydrofolate reductase and the trimethoprim resistance were cotransformed (100%) with the rif marker. These results suggest that the RNA polymerase is altered in its recognition of the gene that specifies dihydrofolate reductase. (+info)N-Acetylation of paraphenylenediamine in human skin and keratinocytes. (4/255)
Skin is the major target of allergic reactions to paraphenylenediamine (PPD). Such small molecules require activation to become immunogenic. The balance between activation and/or detoxification processes is critical for immunogenic potentials of compounds. Therefore, we investigated N-acetylation (NAT) capacities of human skin for PPD to gain a better understanding of its mechanisms of action. PPD is acetylated to monoacetyl-PPD (MAPPD), which in turn is acetylated to N,N'-diacetyl-PPD (DAPPD). This was found using cytosolic fractions from human skin (n = 9) and cultured normal human epidermal keratinocytes (n = 7). The cutaneous activities for MAPPD formation ranged from 0.41 to 3.68 nmol/mg/min (9-fold variation) and DAPPD formation from 0.65 to 3.25 nmol/mg protein/min (5-fold), respectively. Similar results were obtained with keratinocytes. NAT activities toward both substrates, PPD and MAPPD, were correlated in keratinocytes (r = 0.930), suggesting that the reactions were catalyzed by the same enzyme. Formation of MAPPD and DAPPD was competitively inhibited in the presence of p-aminobenzoic acid (300 microM), a typical NAT1 substrate, but not by sulfamethazine. These kinetic characteristics suggest that the acetylation of PPD in human skin and keratinocytes is predominantly attributable to the polymorphic NAT1, although both mRNAs (NAT1 and NAT2) are synthesized in human skin and keratinocytes. The metabolism of PPD by NAT1 in human skin and keratinocytes as well as the virtual absence of NAT2 activity may have important toxicological implications. In the case of PPD, our results emphasize that N-acetylation status may be a susceptibility factor for the development of an allergy to PPD. (+info)Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells. (5/255)
Arylamine N-acetyltransferase-1 (NAT1) is a polymorphically expressed enzyme that is widely distributed throughout the body. In the present study, we provide evidence for substrate-dependent regulation of this enzyme. Human peripheral blood mononuclear cells cultured in medium supplemented with p-aminobenzoic acid (PABA; 6 microM) for 24 h showed a significant decrease (50-80%) in NAT1 activity. The loss of activity was concentration-dependent (EC(50) approximately 2 microM) and selective because PABA had no effect on the activity of constitutively expressed lactate dehydrogenase or aspartate aminotransferase. PABA also induced down-regulation of NAT1 activity in several human cell lines grown at confluence. Substrate-dependent down-regulation was not restricted to PABA. Addition of other NAT1 substrates, such as p-aminosalicylic acid, ethyl-p-aminobenzoate, or p-aminophenol to peripheral blood mononuclear cells in culture also resulted in significant (P <.05) decreases in NAT1 activity. However, addition of the NAT2-selective substrates sulfamethazine, dapsone, or procainamide did not alter NAT1 activity. Western blot analysis using a NAT1-specific antibody showed that the loss of NAT1 activity was associated with a parallel reduction in the amount of NAT1 protein (r(2) = 0.95). Arylamines that did not decrease NAT1 activity did not alter NAT1 protein levels. Semiquantitative reverse transcriptase polymerase chain reaction of mRNA isolated from treated and untreated cells revealed no effect of PABA on NAT1 mRNA levels. We conclude that NAT1 can be down-regulated by arylamines that are themselves NAT1 substrates. Because NAT1 is involved in the detoxification/activation of various drugs and carcinogens, substrate-dependent regulation may have important consequences with regard to drug toxicity and cancer risk. (+info)Sensitive and selective determination of tetracaine and its metabolite in human samples by gas chromatography-mass spectrometry. (6/255)
A sensitive and reliable method was developed for the determination of tetracaine and its metabolite, p-butylaminobenzoic acid, in human samples. Tetracaine and the metabolite, effectively extracted using a liquid-liquid extraction procedure from 0.5 g of sample, were analyzed by gas chromatography-mass spectrometry. Tetracaine was analyzed without derivatization, and the metabolite was analyzed after tert-butylolimethylsilyl derivatization. Dibucaine and p-dimethylaminobenzoic acid were used as internal standards for tetracaine and the metabolite, respectively. The calibration curve for each compound was linear in the concentration range from 10 to 1,000 ng/0.5 g, and the lower limits of detection were 10 ng/g for tetracaine and 0.6 ng/g for the metabolite in whole blood and tissues. The accuracy and precision of the method were evaluated in whole blood and brain at the concentrations of 50 ng/0.5 g and 500 ng/0.5 g for tetracaine and 10 ng/0.5 g and 100 ng/0.5 g for the metabolite. The coefficients of variation ranged from 0.8 to 3.0% for tetracaine and 2.4 to 9.8% for the metabolite. We used this method to determine tetracaine and its metabolite in human whole blood and tissues of an autopsied patient who died during spinal anesthesia induced by tetracaine. (+info)Inhibition of the development of the cellular slime mould Dictyostelium discoideum by omega-aminocarboxylic acids. (7/255)
Four omega-aminocarboxylic acids - epsilon-aminocaproic acid (EACA), trans-4-aminomethylcyclohexane-1-carboxylic acid (t-AMCHA), p-aminomethylbenzoic acid (PAMBA) and omega-aminocaprylic acid (OACA) -- prevented fruiting body formation of the cellular slime mould Dictyostelium discoideum. At concentrations of 40 mM, 75 mM, 10 mM and 5 mM, respectively, they allowed aggregation but prevented all further development at 24 degrees C. At lower concentrations, EACA allowed fruiting body formation but with a reduced number of spores per fruiting body. Only t-AMCHA had a significant inhibitory effect on the growth of myxamoebae. EACA affected development only if it was present between 8 and 16 h after the cells were deposited on the filters. Its effect was enhanced by high salt concentrations and by higher temperature, and was also dependent on the manner in which the cells were grown. Only strains capable of axenic growth displayed this sensitivity to EACA, although strains carrying only one of the genetic markers for axenic growth (axe A) were partially sensitive. (+info)The effect of epsilon-aminocaproic acid on biochemical changes in the development of the cellular slime mould Dictyostelium discoideum. (8/255)
epsilon-Aminocaproic acid (EACA) inhibited the development of Dictyostelium discoideum strain AX2 after the aggregation stage. Biochemical changes that occurred early in development (loss of cellular protein, RNA and carbohydrate; increase in the specific activity of N-acetylglucosaminidase, alpha-mannosidase, threonine deaminase and leucine aminopeptidase) were not affected by concentrations of EACA which blocked development; but biochemical changes that occurred later (synthesis of carbohydrate, increase in the specific activity of UDP-glucose pyrophosphorylase) were inhibited. Spores from fruiting bodies formed in the presence of low concentrations of EACA were larger, more spherical and less able to survive heat treatment than spores from fruiting bodies of control (no EACA) cells. (+info)
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4-Aminobenzoic acid
"Para-aminobenzoic acid". Medline Plus Medical Encyclopedia. United States National Institutes of Health. Retrieved 24 January ... Toxicity, Local Anesthetics: eMedicine Emergency Medicine "Aminobenzoic acid". Drug Information Portal. U.S. National Library ... "Synthesis of para-Amino Benzoic Acid-TiO2 Hybrid Nanostructures of Controlled Functionality by an Aqueous One-Step Process". ... "Synthesis of para-Amino Benzoic Acid-TiO2 Hybrid Nanostructures of Controlled Functionality by an Aqueous One-Step Process". ...
3-Aminobenzoic acid
... (also known as meta-aminobenzoic acid or MABA) is an organic compound with the molecular formula ... It consists of a benzene ring substituted with an amino group and a carboxylic acid. Aminomethylbenzoic acid Anthranilic acid 4 ... Aminobenzoic acid Arene substitution pattern Non-proteinogenic amino acids m-Carboxyaniline - Compound Summary, PubChem. 3- ... aminobenzoic acid, Medical Subject Headings database. Haynes, William M., ed. (2016). CRC Handbook of Chemistry and Physics ( ...
Aminomethylbenzoic acid
... (more precisely, 4-aminomethylbenzoic acid or p-aminomethylbenzoic acid, PAMBA) is an antifibrinolytic ... 4-Aminobenzoic acid Verstraete M (March 1985). "Clinical application of inhibitors of fibrinolysis". Drugs. 29 (3): 236-61. doi ...
Butamben
Brill HC (June 1921). "Esters of Aminobenzoic Acids". Journal of the American Chemical Society. 43 (6): 1320-1323. doi:10.1021/ ... that is mildly soluble in water (1 part in 7000) and soluble in alcohol, ether, chloroform, fixed oils, and dilute acids. It ... Morogina OK, Nasibulin AA, Klyuev MV (1998). "Liquid-Phase Hydrogenation of p-Nitrobenzoic Acid Esters on Palladium Catalysts ... Hosangadi BD, Dave RH (August 1996). "An efficient general method for esterification of aromatic carboxylic acids". Tetrahedron ...
Protomer
Examples in chemistry include tyrosine and 4-aminobenzoic acid. The former may be deprotonated to form the carboxylate and ...
4-Nitrobenzoic acid
"Safety data for p-nitrobenzoic acid". Retrieved 11 April 2010. "p-Nitrobenzoic acid". Archived from the original on 7 May 2010 ... "Material Safety Data Sheet - P-nitrobenzoic acid MSDS". Archived from the original on 7 August 2011. Retrieved 11 April 2010. ( ... "Dissociation Constants Of Organic Acids And Bases". Retrieved 11 April 2010. "Bordwell pKa Table (Acidity in DMSO)". Retrieved ... ISBN 3527306730.. O. Kamm; A. O. Matthews (1922). "p-Nitrobenzoic Acid". Org. Synth. 2: 53. doi:10.15227/orgsyn.002.0053. " ...
Myeloperoxidase
Hypochlorous acid and tyrosyl radical are cytotoxic, so they are used by the neutrophil to kill bacteria and other pathogens. ... However, this hypochlorous acid may also cause oxidative damage in host tissue. Moreover, MPO oxidation of apoA-I reduces HDL- ... MPO is a member of the XPO subfamily of peroxidases and produces hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) and ... MPO is most abundantly expressed in neutrophil granulocytes (a subtype of white blood cells), and produces hypohalous acids to ...
Anthranilic acid
IPCS Acton, Q. Ashton (2013). Aminobenzoic Acids-Advances in Research and Application (2013 ed.). Atlanta: ScholarlyEditions. p ... tolfenamic acid, flufenamic acid, and meclofenamic acid are derived from fenamic acid or anthranilic acid and are called " ... Fenamic acid is a derivative of anthranilic acid,: 235 which in turn is a nitrogen isostere of salicylic acid, which is the ... Anthranilic acid is an aromatic acid with the formula C6H4(NH2)(CO2H) and has a sweetish taste. The molecule consists of a ...
Diethylethanolamine
... is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging ... It can be reacted with 4-aminobenzoic acid to make procaine. DEAE can be used as a precursor for DEAE-cellulose resin, which is ...
Benzocaine
... is the ethyl ester of p-aminobenzoic acid (PABA). It can be prepared from PABA and ethanol by Fischer esterification ... ester of para-aminobenzoic acid as a local anaesthetic), Klinische Wochenschrift, vol. 39, pages 373-375. Guénette, SA; Giroux ... In industrial practice, the reducing agent is usually iron and water in the presence of a little acid. Benzocaine was first ... Benzocaine is sparingly soluble in water; it is more soluble in dilute acids and very soluble in ethanol, chloroform, and ethyl ...
Dimethocaine
27 (4): 647-50. doi:10.1016/0306-3623(95)02079-9. PMID 8853299. Blatt SL, Takahashi RN (April 1998). "Memory-impairing effects ... 58 (4): 220-8. CiteSeerX 10.1.1.327.1264. doi:10.1002/syn.20199. PMID 16206183. S2CID 15631376. TOKYO CHEMICAL INDUSTRY CO., ... When inhaled, dimethocaine starts working in 10-30 minutes, with highest effects at 60-120 minutes and until 4-6 hours there is ... 31 (4): 555-9. doi:10.1590/s0100-879x1998000400013. PMID 9698809. Greene, Shaun L. (2013). "Miscellaneous Compounds". Novel ...
Balsalazide
... obtained by coupling para-aminobenzoic acid and glycine. That product is then treated with nitrous acid to give the diazonium ... Reaction of this species with salicylic acid proceeds at the position para to the phenol to give balsalazide. "Colazide 750mg ... Balsalazide releases mesalazine, also known as 5-aminosalicylic acid, or 5-ASA, in the large intestine. Its advantage over that ... See Ex 4 for Balsalazide proper. Same protocol but uses β-Alanine. Starting material is 4-aminohippuric acid, ...
Bumetanide
Feit PW (May 1971). "Aminobenzoic acid diuretics. 2. 4-Substituted-3-amino-5-sulfamylbenzoic acid derivatives". Journal of ... Finally, reacting this with butyl alcohol in the presence of sulfuric acid, followed by treatment with sodium hydroxide to ... In the first stage of synthesis, it undergoes sulfonylchlorination by chlorosulfonic acid, forming 4-chloro-3- ... chlorosulfonylbenzoic acid, which is further nitrated with nitric acid to 4-chloro-3-chlorosulfonyl-5-nitrobenzoic acid. ...
N-acetyltransferase
Polymorphisms of NAT2 include the single amino acid substitutions R64Q, I114T, D122N, L137F, Q145P, R197Q, and G286E. These are ... of their amino acid sequence. Both also have an active site cysteine residue (Cys68) in the N-terminal region. Further, all ... Human NAT1 preferentially acetylates 4-aminobenzoic acid (PABA), 4 amino salicylic acid, sulfamethoxazole, and sulfanilamide. ...
Pterin
Folates are pterins that contain p-aminobenzoic acid connected to the methyl group at position 6 of the pteridine ring system ( ... Folic acid Molybdopterin Pteridine Tetrahydrobiopterin Tetrahydromethanopterin Wijnen, B.; Leertouwer, H. L.; Stavenga, D. G. ( ... The aromatic amino acid hydroxylases include phenylalanine hydroxylase, tyrosine hydroxylase, and tryptophan hydroxylases. They ... Substituted pteridines are intermediates in the biosynthesis of dihydrofolic acid in many microorganisms. The enzyme ...
Chorismic acid
Chorismate is transformed into para-aminobenzoic acid by the enzymes 4-amino-4-deoxychorismate synthase and 4-amino-4- ... 3-Dihydroxybenzoic acid (DHB) used for enterobactin biosynthesis The plant hormone salicylic acid Many alkaloids and other ... The name chorismic acid derives from a classical Greek word χωρίζω meaning "to separate", because the compound plays a role as ... Chorismic acid, more commonly known as its anionic form chorismate, is an important biochemical intermediate in plants and ...
Personal lubricant
41 (4): 400-4. PMID 8894797. Ellington J, Daughtery S. Prevalence of vaginal dryness in trying-to-conceive couples" Fertil ... Additionally, a commonly used numbing agent benzocaine can cause an allergic reaction in those with an allergy to PABA (4- ... aminobenzoic acid). Some lubricants are conveniently packaged for ease of application. Many of these products such as ... 79: 21-2. doi:10.1016/s0015-0282(03)00127-4. Steiner, AZ; Long, DL; Tanner, C; Herring, AH (Jul 2012). "Effect of vaginal ...
Procaine
Method for the prepareation of p-aminobenzoic acid alkamine esters]", published 1906-12-11, assigned to Höchst A.M. ; DE 194748 ... is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-amino benzoic acid (PABA), which ... Method for the prepareation of p-aminobenzoic acid alkamine esters]", published 1908-01-28, assigned to Höchst A.M. , ... the resulting acid chloride is then esterified with 2-diethylaminoethanol to give Nitrocaine. Finally, the nitro group is ...
Chloroprocaine
58 (4): 384-91. doi:10.1007/s12630-010-9450-x. PMID 21203878. S2CID 31870857. Gissen AJ, Datta S, Lambert D (July 1984). "The ... 59 (6): 452-4. doi:10.1213/00000539-198006000-00014. PMID 7189987. Förster JG, Kallio H, Rosenberg PH, Harilainen A, Sandelin J ... 151 (3): 322-4. doi:10.1016/0002-9378(85)90295-9. PMID 3970100. Chestnut: Obstetric Anesthesia, 3rd ed, p333. Hughes: ... The hydrochloride salt of 4-amino-2-chlorobenzoyl chloride is made by the reaction of 2-chloro-4-aminobenzoic acid with thionyl ...
Nitrobenzoic acid
2-Nitrobenzoic acid is prepared by oxidation of 2-nitrotoluene. 3-Nitrobenzoic acid is a precursor to 3-aminobenzoic acid, ... Nitrobenzoic acid[which?] can be prepared through the oxidation of styrene in boiling nitric acid. The salts and esters of ... Nitrobenzoic acids are derivatives of benzoic acid. Two are commercially important. They are about ten times more acidic than ... It can be prepared by nitration of benzoic acid. It also can be prepared by treating benzaldehyde under nitration conditions, a ...
6S)-6-Fluoroshikimic acid
Shikimic acid Davies GM, Barrett-Bee KJ, Jude DA, Lehan M, Nichols WW, Pinder PE, Thain JL, Watkins WJ, Wilson RG (1994). "(6S ... 6S)-6-Fluoroshikimic acid is an antibacterial agent acting on the aromatic biosynthetic pathway. It may be used against ... 6-Fluoro-Shikimic Acid". Antimicrobial Agents and Chemotherapy. 39 (1): 87-93. doi:10.1128/AAC.39.1.87. PMC 162490. PMID ... 6-Fluoroshikimic Acid, an Antibacterial Agent Acting on the Aromatic Biosynthetic Pathway". Antimicrobial Agents and ...
Padimate O
... yellowish water-insoluble oily liquid is an ester formed by the condensation of 2-ethylhexanol with dimethylaminobenzoic acid. ... 35 (4): 546-9. doi:10.1016/S0190-9622(96)90677-5. PMID 8859281. Kerr, Caroline (1998). "The effects of two UVB radiation- ... 9 (3-4): 323-334. doi:10.1016/1011-1344(91)80169-I. PMID 1919875. Bissett, Donald L; McBride, James F (1996). "Synergistic ... Padimate O is an organic compound related to the water-soluble compound PABA (4-aminobenzoic acid) that is used as an ...
Hilkka I. Kenttämaa
"Laser-Induced Acoustic Desorption/Electron Ionization of Amino Acids and Small Peptides". Journal of the American Society for ... 2 (4): 350-353. 1991-08-01. doi:10.1016/1044-0305(91)80027-5. ISSN 1044-0305. "News and Views" (PDF). American Society for Mass ... 4 (4): 2316-2322. doi:10.1021/acssuschemeng.5b01776. ISSN 2168-0485. Fingas, Merv, ed. (2022-05-23). The Chemistry of Oil and ... 4 (2): 806-813. doi:10.1039/C2SC21657D. ISSN 2041-6520. Parsell, Trenton; Yohe, Sara; Degenstein, John; Jarrell, Tiffany; Klein ...
Reed McNeil Izatt
pK, ΔHo, and ΔSo values for proton ionization from o-, m-, and p-Aminobenzoic Acids and their methyl esters at 25 °C. J. Phys. ... nucleic acid chemistry, metal cyanide chemistry, chemical separations, amino acid microspecies formation, and high- temperature ... Izatt, R. et al Sites and thermodynamic quantities associated with proton and metal ion interaction with ribonucleic acid, ... deoxyribonucleic acid, and their constituent bases, nucleosides, and nucleotides. Chem. Rev. 1971 vol 71 pp439-481. Oscarson, J ...
Procainamide
Other metabolites of procainamide include desethyl-N-acetylprocainamide, desethylprocainamide, p-aminobenzoic acid, which are ... These are aromatic carboxylic acid derivatives consisting of an amide with a benzamide moiety and a triethylamine attached to ... 4 (5): 507-11. doi:10.1111/j.1365-2125.1977.tb00777.x. PMC 1429167. PMID 911600. Uetrecht J, Zahid N, Rubin R (January 1988). " ... N-acetyl-4-aminobenzoic acid as well as N-acetyl-3-hydroxyprocainamide, N-acetylprocainamide-N-oxide and N-acetyl-4- ...
Tetramethylurea
... including acids such as acetic acid or bases such as pyridine and an excellent solvent for organic substances such as ε- ... caprolactam or benzoic acid and dissolves even some inorganic salts such as silver nitrate or sodium iodide. Due to its ... such as isophthalic acid) and aromatic diamines (such as 1,3-diaminobenzene (m-phenylenediamine)) to aramids such as poly (m- ... A modification of the Koenigs-Knorr reaction for building glycosides from 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide ( ...
Non-proteinogenic amino acids
... ic acid.) Most natural amino acids are α-amino acids in the L conformation, but some exceptions exist. Some non-α-amino acids ... Whereas glutamic acid possess one γ-carboxyl group, Carboxyglutamic acid possess two. Hydroxyproline. This imino acid differs ... and a carboxylic acid (-COOH) functional group is an amino acid. The proteinogenic amino acids are small subset of this group ... amino acids. Other amino acids are solely found in abiotic mixes (e.g. α-methylnorvaline). Over 30 unnatural amino acids have ...
List of local anesthetics
34 (4): 1002-1013. doi:10.1002/hlca.19510340404. S. M. McElvain and T. P. Carney, J. Amer. Chem. Soc, 68, 2592 (1946). K. ... 4-Aminobenzoic acid Amino amide Amino esters Anesthesia Anesthetic Brachial plexus block Cocaine analogues: local anesthetics ... Soc, 61, 1713 (1939). Clinton, R. O.; Salvador, U. J.; Laskowski, S. C.; Wilson, Mary (February 1952). "Derivatives of 4-Amino- ... 2-hydroxybenzoic Acid. II". Journal of the American Chemical Society. 74 (3): 592-598. doi:10.1021/ja01123a005. N. Lofgren, C. ...
PABA
... also known as para-aminobenzoic acid or PABA, an organic compound Barter Island LRRS Airport (ICAO: PABA) Paba Upazila, ... the governing body of baseball in the Philippines 4-Aminobenzoic acid, ...
Rubrivivax benzoatilyticus
The aromatic compounds that can be consumed as food for this bacteria are benzoic acid, 2-aminobenzoic acid (anthranilate), 4- ... aminobenzoic acid, 4-hydroxybenzoic acid, phthalate, phenylalanine, trans-cinnamate, benzamide, salicylate, cyclohexanone, ...
Competitive inhibition
... active site by mimicking the substrate para-aminobenzoic acid (PABA). This prevents the substrate itself from binding which ... Bacteria must synthesize folic acid because they do not have a transporter for it. Without folic acid, bacteria cannot grow and ... These fatty acids inhibitors have been used as drugs to relieve pain because they can act as the substrate, and bind to the ... Essential fatty acids form the prostaglandins; when this was discovered, it turned out that these were actually very good ...
Pyrimethamine
... an enzyme that participates in folic acid synthesis from para-aminobenzoic acid. Hence, sulfonamides work synergistically with ... Folinic acid (leucovorin) is a folic acid derivative converted to tetrahydrofolate, the primary active form of folic acid, in ... Pyrimethamine is classified as a folic acid antagonist. It works by inhibiting folic acid metabolism and therefore the making ... Tetrahydrofolic acid is essential for DNA and RNA synthesis in many species, including protozoa. It has also been found to ...
Controlled Drugs and Substances Act
2-acetamidobenzoic acid) and its salts Anthranilic acid (2-aminobenzoic acid) and its salts Ephedrine (erythro-2-(methylamino)- ... 2-thiobarbituric acid) Thiamylal (5-allyl-5-(1-methylbutyl)-2-thiobarbituric acid) Thiobarbituric acid (2-thiobarbituric acid) ... barbituric acid) Vinylbital (5-(1-methylbutyl)-5-vinylbarbituric acid) but not including: Barbituric acid (2,4,6(1H,3H,5H)- ... barbituric acid) Sigmodal (5-(2-bromoallyl)-5-(1-methylbutyl) barbituric acid) Talbutal (5-allyl-5-sec-butylbarbituric acid) ...
Actinic cheilitis
... para-aminobenzoic acid), or sun blocking agents (e.g. zinc oxide, titanium oxide) prior to sun exposure. This condition is ... Chemical peeling with 50% trichloroacetic acid has also been evaluated, but results have been poor. Healing usually takes 7-10 ... ISBN 978-1-60327-519-4. Wenig BM (7 May 2012). Atlas of Head and Neck Pathology. Elsevier Health Sciences. pp. 331-332. ISBN ... ISBN 978-0-7020-4948-4. Treister NS; Bruch JM (2010). Clinical oral medicine and pathology. New York: Humana Press. p. 121. ...
Aminodeoxychorismate synthase
It is part of a pathway for the biosynthesis of para-aminobenzoic acid (PABA); a precursor for the production of folates. ... can be converted to para-aminobenzoic acid by the enzyme 4-amino-4-deoxychorismate lyase (PabC). This enzyme belongs to the ... The chorismate binding site on PabB consists of amino acids residues that make up beta sheet core and the two key alpha helices ... Specifically, aminodeoxychorismate synthase is a transaminase that transfers an amino group to a keto acid. The systematic name ...
Sulfamethoxazole
... , a sulfanilamide, is a structural analog of para-aminobenzoic acid (PABA). They compete with PABA to bind to ... It prevents folic acid synthesis in the bacteria that must synthesize their own folic acid. Mammalian cells, and some bacteria ... Inhibiting the production of dihydrofolate intermediate interferes with the normal bacterial synthesis of folic acid (folate). ... and amino acids synthesis, including serine, glycine and methionine. Hence, blockage of folate production inhibits the folate- ...
Lactase persistence
Proposed mechanisms are: nutritional advantage of milk; low content of p-aminobenzoic acid compared to non-milk diets; intake ... 45 (4): 487-8. PMC 1683494. PMID 2518796. Murray RD, Ailabouni AH, Powers PA, McClung HJ, Li BU, Heitlinger LA, Sloan HR (July ... 94 (4): 496-510. doi:10.1016/j.ajhg.2014.02.009. PMC 3980415. PMID 24630847. "Why 65% of Humans Can't Drink Milk". Troelsen JT ... 4 (7): e6369. Bibcode:2009PLoSO...4.6369G. doi:10.1371/journal.pone.0006369. PMC 2711333. PMID 19629189. Cook, G C; al-Torki, M ...
Bentiromide
It is broken down by the pancreatic enzyme chymotrypsin, yielding p-aminobenzoic acid (PABA). The amount of PABA and its ... The resulting L-amide is selectively hydrolyzed by sequential use of dimsyl sodium (NaDMSO) and dilute acid to give bentiromide ... XLogP=3.201 H_bond_donor=4[citation needed] H_bond_acceptor=5[citation needed] It is synthesized by amide formation between ... 4). Chronic pancreatitis Bentiromide - Compound Summary, PubChem. Micromedex Detailed Consumer Information on bentiromide. P. L ...
Bernard Ogilvie Dodge
1946, "MUTANT STRAINS OF NEUROSPORA DEFICIENT IN PARA-AMINOBENZOIC ACID", MA Thesis, Stanford University Hollaender, A., ... Ultraviolet Irradiation", American Journal of Botany 32(4):226-235 Also: "Quantitative effects of radiation on mutation ...
Misuse of Drugs Act (Singapore)
10-didehydro-6-methylergoline-8-carboxylic acid N-acetylanthranilic acid also known as N-Acetyl-o-aminobenzoic acid Nitrazepam ... acid Methyl ethyl ketone also known as 2-Butanone Phenylacetic acid also known as Benzeneacetic acid or a-Toluic acid ... known as Acetic oxide Acetone also known as 2-Propanone or Dimethyl ketone Anthranilic acid also known as o-Aminobenzoic acid ... GHB Ketamine Lysergic acid diethylamide (LSD), and other lysergides MDMA (ecstasy) Mescaline Methamphetamine Methaqualone ...
Butacaine
"Dialkylaminoalkanol Esters of p-Aminobenzoic Acid". Journal of the American Chemical Society 59 (11): 2248-2252. doi:10.1021/ ... 4) gives CID:4588466 (5). The reduction of the nitro group completed the synthesis of butacaine (6). Isobucaine Burnett, W. B ...
Antimicrobial resistance
Alteration of metabolic pathway: for example, some sulfonamide-resistant bacteria do not require para-aminobenzoic acid (PABA ... an important precursor for the synthesis of folic acid and nucleic acids in bacteria inhibited by sulfonamides, instead, like ... Gever J (4 February 2011). "Pfizer Moves May Dim Prospect for New Antibiotics". MedPage Today. Archived from the original on 14 ... 4 (2): 95-111. doi:10.1016/j.ijpddr.2014.02.002. PMC 4095053. PMID 25057459. Visser BJ, van Vugt M, Grobusch MP (October 2014 ...
Niphates digitalis
5-di-nitro-benzoic acid and 3,5-di-nitro-salicylic acid". Acta Crystallogr E. 72 (3): 382-386. doi:10.1107/S205698901600267X. ... with the ring-substituted benzoic acid analogues 4-amino-benzoic acid, 3, ...
Local anesthetic
Allergic reactions to the esters is usually due to a sensitivity to their metabolite, para-aminobenzoic acid, and does not ... Gazourian A (4 April 1985). "Cocaine's use: From the Incas to the U.S." Boca Raton News. Retrieved 2 February 2014. López- ... 54 (4): 715-730. doi:10.1016/j.cden.2010.06.016. PMID 20831934. Shabazfar N, Daubländer M, Al-Nawas B, Kämmerer PW (2014). " ... 103 (4): 571-575. doi:10.14219/jada.archive.1981.0307. PMID 6945341. Smith GN, Walton RE, Abbott BJ (December 1983). "Clinical ...
4-aminobenzoic acid (CHEBI:30753)
An aminobenzoic acid in which the amino group is para to the carboxy group.. ... aminobenzoic acid (CHEBI:22495) 4-aminobenzoic acid (CHEBI:30753) is conjugate acid of 4-aminobenzoate (CHEBI:17836) ... Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Br. o. nsted base). ... benzoic acid (CHEBI:30746) 4-aminobenzoic acid (CHEBI:30753) has role Escherichia coli metabolite (CHEBI:76971) 4-aminobenzoic ...
4-Aminobenzoic acid - ZELLX®
4-Aminobenzoic Acid
- PlantMedia
Aminobenzoic acids their derivatives are important for the preparation of other pharmaceutical products, dyes, flavors, and ... It is a starting material in the manufacture of target esters, salts, folic acid, azo dyes and other organic compounds. It is ... This compound is a part of folic acid molecule and was called Vitamin BX as it is a component of pteroylglutamate. ... Aminobenzoic acids their derivatives are important for the preparation of other pharmaceutical products, dyes, flavors, and ...
4-AMINOBENZOIC ACID POTAS POWD
This site is not designed to and does not provide medical advice, professional diagnosis, opinion, treatment or services to you or to any other individual. Please consult a licensed healthcare professional or veterinarian about diagnosis and treatment. Information and statements on this site have not been evaluated by the Food and Drug Administration ...
Para-aminobenzoic acid: MedlinePlus Medical Encyclopedia
Para-aminobenzoic acid (PABA) is a natural substance. It is often used in sunscreen products. PABA is sometimes called vitamin ... Para-aminobenzoic acid (PABA) is a natural substance. It is often used in sunscreen products. PABA is sometimes called vitamin ... Para-aminobenzoic acid (also known as 4-aminobenzoic acid) can be harmful in large amounts. ...
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Polymyxin B Sulfate,Dorzolamide HCl,Tretinoin,Isotretinoin,4,6-Dichloropyrimidine, 3-Hydroxyacetophenone, p-aminobenzoic acid...
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Deciphering the label on your sunscreen bottle - Curious
Cas 497-18-7,Carbohydrazide | lookchem
Carbazic acid, hydrazide;carbazicacid,hydrazide;Carbodihydrazide;Carbonic acid, dihydrazide ... Reacts with nitrous acid to form the explosive carbonic dazide. When heated to decomposition it emits toxic fumes of NOx. ... Treasury: ventilation, low-temperature and drying; it should be stored separately from strong acids and strong oxidants. ... With hydrazine hydrate In water; acetic acid for 6h; hydrazinolysis; Heating;. A 45%. B n/a. ...
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Chemical Database: Benzoic acid, 4-chloro-2-((2-methoxyphenyl)amino)-, 2-(aminothioxomethyl)hydrazide (EnvironmentalChemistry...
This page contains information on the chemical Benzoic acid, 4-chloro-2-((2-methoxyphenyl)amino)-, 2-(aminothioxomethyl) ... amino) benzoic acid 2-(aminothioxomethyl) hydrazide*Benzoic acid, 4-chloro-2-((2-methoxyphenyl) amino)-, 2-(aminothioxomethyl) ... Benzoic acid, 4-chloro-2-((2-methoxyphenyl) amino)-, 2-(aminothioxomethyl) hydrazide. Identifications. *CAS Number: 195370-36-6 ... Chemical Database - Benzoic acid, 4-chloro-2-((2-methoxyphenyl)amino)-, 2-(aminothioxomethyl)hydrazide. EnvironmentalChemistry. ...
p-Aminobenzoic acid - Carbomer
Procain - Wicipedia
methyl 4-amino-3-methoxybenzoate 41608-64-4, China methyl 4-amino-3-methoxybenzoate 41608-64-4 Manufacturers, China methyl 4...
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Iheezo (chloroprocaine ophthalmic) dosing, indications, interactions, adverse effects, and more
4. This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty ... Clinically, the order of loss of nerve function is as follows: (1) pain, (2) temperature, (3) touch, (4) proprioception, and (5 ... hydrolysis results in beta-diethylaminoethanol and 2-chloro-4-aminobenzoic acid, which inhibit sulfonamides action ...
Megaloblastic Anemia: Practice Essentials, Pathophysiology, Etiology
Folic acid for the prevention of neural tube defects: U.S. Preventive Services Task Force recommendation statement. Ann Intern ... Cobalamin, folic acid, and homocysteine. Nutr Rev. 2009 May. 67 Suppl 1:S69-72. [QxMD MEDLINE Link]. ... Elevated methylmalonic acid (MMA) may be responsible. Cobalamin deficiency leads to reduced cofactor 5-deoxyadenosylcobalamin ... Dary O. Nutritional interpretation of folic acid interventions. Nutr Rev. 2009 Apr. 67(4):235-44. [QxMD MEDLINE Link]. ...
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Sunrise Yeast Media - Supplements, Additives and Raw Materials | Krackeler Scientific, Inc.
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Targeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolates - Fingerprint
...
Pendimethalin (Ref: AC 92553)
... amino)benzoic acid. M455H056. Animal. -. -. ... Rat 4 hr (nose only liquid aerosol). -. Other Mammal toxicity ... 7-amino-5-methyl-1-(pentan-3-yl)-1H-benzimidazole-6-carboxylic acid. M455H017-1. Animal. -. -. ... 4. A2 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III ... 4-(hydroxymethyl)-3-methyl-2,6-dinitrophenolate. -. Animal. -. -. 4-((1-hydroxypentan-3-yl)amino)-2-methyl-3,5-dintrobenzoic ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
D10.251.400.143 Butyric Acid D2.241.81.160.140 D2.241.81.114.750 D10.251.400.241.140 D10.251.400.143.500 Caffeic Acids D2.241. ... B5.80.750.450 Keto Acids D2.241.607 D2.241.755 Ketoglutaric Acids D2.241.607.465 D2.241.755.465 L-Selectin D23.50.301.264. ... D2.705.675 Phosphoric Acid Esters D2.705.673 D2.705.400 (Replaced for 2012 by Organophosphates) Phosphorous Acids D2.705.676 ... Aminoethylphosphonic Acid D2.705.50 D2.705.429.249 Aminohippuric Acids D2.241.223.100.120.67 D2.241.223.100.100.100 D2.241. ...
SMART: BCL domain annotation
... amino}benzoic acid. 4oq6. Crystal Structure of Human MCL-1 Bound to Inhibitor 4-hydroxy-4-propylbiphenyl-3-carboxylic acid. ... 2017) Nucleic Acids Res doi: 10.1093/nar/gkx922. Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937 ... Crystal structure of Bcl-Xl complex with 4-(5-butyl-3-(hydroxymethyl)-1-phenyl-1h-pyrazol-4-yl)-3-(3,4-dihydro-2(1h)- ... Crystal Structure of Human MCL-1 Bound to Inhibitor 4-(4-methylnaphthalen-1-yl)-2-{[(4-phenoxyphenyl)sulfonyl] ...
Effect of Dietary p-Aminobenzoic Acid on Murine Plasmodium yoelii Infection<...
Kicska GA, Ting LM, Schramm VL, Kim K. Effect of Dietary p-Aminobenzoic Acid on Murine Plasmodium yoelii Infection. Journal of ... Kicska, G. A., Ting, L. M., Schramm, V. L., & Kim, K. (2003). Effect of Dietary p-Aminobenzoic Acid on Murine Plasmodium yoelii ... Effect of Dietary p-Aminobenzoic Acid on Murine Plasmodium yoelii Infection. Gregory A. Kicska, Li Min Ting, Vern L. Schramm, ... Kicska, GA, Ting, LM, Schramm, VL & Kim, K 2003, Effect of Dietary p-Aminobenzoic Acid on Murine Plasmodium yoelii Infection ...
Pesquisa | Portal Regional da BVS
... amino] benzoic acid (L1), has been synthesized by the condensation reaction. It has been characterized by Fourier transform ... A doubling in uric acid was associated with an effect estimate of 0.57 (95% CI 0.49-0.65) and 0.77 (0.73-0.81) for ... RESULTS: In both studies, high uric acid was associated with lower risk of hospitalization as in-patient or out-patient with ... We tested the hypothesis that high levels of the antioxidant uric acid are associated with lower risk of hospitalization with ...
US9907751B2 - Composition and method of use of colchicine oral liquid - Google Patents
150000001413 amino acids Chemical class 0.000 description 3 * 229960004050 aminobenzoic acid Drugs 0.000 description 3 ... 229960005070 ascorbic acid Drugs 0.000 description 2 * UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Chemical compound data:image/svg+xml ... TYQCGQRIZGCHNB-JLAZNSOCSA-N L-ascorbic acid Chemical compound data:image/svg+xml;base64, ... KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound data:image/svg+xml;base64, ...
Development of Scaled-Up Synthetic Method for Retinoid X Receptor Agonist NEt-3IB Contributing to Sustainable Development Goals
JMIR Research Protocols - The Karlsruhe Metabolomics and Nutrition (KarMeN) Study: Protocol and Methods of a Cross-Sectional...
Completeness of the 24-hour urine was checked with the para-aminobenzoic acid (PABA) method [54]. For 24-hour urine collection ... amino acids, organic acids, sugars, sugar alcohols, other polyols, etc. Because some isomeric sugar species cannot be ... metabolites that can be detected include organic acids, amino acids, amines, sugars, sugar alcohols, and others. ... For this reason, we used a targeted GC-MS analysis method [61] to determine plasma fatty acids as methyl esters, with minor ...
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PABABenzoic acidAminoEthylCamphorFolicDerivativesMethylAminosalicylic AcidEsterSynthesisOrganicNiacinIngredientSodiumAceticReactionsChloroformSuppliersDonorBacteriaSynonymsBiotinProcaineAttached to the benzeneNicotinicBenzeneAromaticHydrazideSUNSCREENSFatty AcidsSaltsSynthesisButylAcetic AcidPhenylIntermediatesDerivativeFolateEstersAmino acidOleic AcidLactic AcidAnthranilic acidAscorbicComplexesMetabolismPowderInorganicOrganic compoundsFolic acid deficMandelicZincVitaminPuritySodium SaltBiomarkerGLUTAMIC ACID
PABA6
- 4-aminobenzoic acid, also known as para-aminobenzoic acid (PABA), is an aminobenzoic acid whereby the amino group is para to the carboxy group. (zellx.de)
- Para-aminobenzoic acid (PABA) is a natural substance. (medlineplus.gov)
- PABA stands for para-aminobenzoic acid. (science.org.au)
- Plasmodia species, unlike humans, can utilize p-aminobenzoic acid (PABA) for the de novo generation of folate. (elsevier.com)
- Hydrolysis of amino ester compounds yields para -aminobenzoic acid (PABA), a well-known allergen, as an intermediate metabolite. (medscape.com)
- PABA (pantothenic acid) can contribute to normal mental performance. (evonutrition.com)
Benzoic acid4
- Beantown Chemical Corporation manufactures 4-(Boc-amino)benzoic acid, 97% 5g, for sale through ChemDirect. (chemdirect.com)
- Save time and money when you buy 4-(Boc-amino)benzoic acid, 97% 5g online through ChemDirect. (chemdirect.com)
- We previously reported the retinoid X receptor (RXR) agonist 4-(ethyl(3-isobutoxy-4-isopropylphenyl)amino)benzoic acid (NEt-3IB, 1 ) as a small-molecular drug candidate to replace biopharmaceuticals for the treatment of inflammatory bowel disease. (go.jp)
- 1 Capsule Contains: Thiamine Nitrate 60mg, Calcium Pantothenate 60mg, Medicinal Yeast 100mg, Cystine 20mg, Keratin 20mg, P-Amino-Benzoic Acid 20mg, Indigotine (E132) and Other Excipients. (taneya.com)
Amino8
- An aminobenzoic acid in which the amino group is para to the carboxy group. (ebi.ac.uk)
- The specific sequence of amino acids determines the shape the polypeptide will take, during protein folding, and the function of the protein. (lecturio.com)
- The current knowledge about the genetics and physiology of glycerol uptake and catabolism in the versatile industrial biotechnology production host Saccharomyces cerevisiae has been mainly based on auxotrophic laboratory strains, and carried out in the presence of growth-supporting supplements such as amino acids and nucleic bases. (biomedcentral.com)
- Amino acids are basic building stones of the „hair" protein keratin, which forms the structure of hair and nails and decides about their quality. (vitar.eu)
- 4-Amino-3-hydroxybenzoic acid CAS 2374-03-0 is Yellow-brown to brown Crystalline Powder. (believechemical.com)
- Believe Chemical is a leading China 4-Amino-3-hydroxybenzoic acid CAS 2374-03-0 manufacturer, supplier and exporter. (believechemical.com)
- Adhering to the pursuit of perfect quality of products, so that our 4-Amino-3-hydroxybenzoic acid CAS 2374-03-0 have been satisfied by many customers. (believechemical.com)
- Vitality Liquid Multivitamin contains a full complex of vitamins, minerals, antioxidants, amino acids and a super greens blend, to balance the immune system and support overall health. (cbdnectarnurse.com)
Ethyl3
- Soluble in glacial acetic acid, chloroform and ethyl acetate. (plantmedia.com)
- Ethoxylated ethyl 4-aminobenzoic acid. (science.org.au)
- Hydrophilic interaction liquid chromatography of anthranilic acid-labelled oligosaccharides with a 4-aminobenzoic acid ethyl ester-labelled dextran hydrolysate internal standard. (ox.ac.uk)
Camphor2
- 4-Methylbenzylidene camphor. (science.org.au)
- 4-methylbenzylidene camphor (4MBC) - Sunscreen ingredient shown to cause coral bleaching. (badgerbalm.com)
Folic6
- This compound is a part of folic acid molecule and was called Vitamin BX as it is a component of pteroylglutamate. (plantmedia.com)
- It is a starting material in the manufacture of target esters, salts, folic acid, azo dyes and other organic compounds. (plantmedia.com)
- Vitamin B12 deficiency (eg, pernicious anemia), folic acid deficiency, and certain medications are the most common causes of megaloblastic anemia, a macrocytic anemia. (medscape.com)
- An aminobenzoic acid isomer that combines with pteridine and GLUTAMIC ACID to form FOLIC ACID . (bvsalud.org)
- Vitamin B12 and folic acid contribute to normal homo-cysteine metabolism, an important factor in heart health. (evonutrition.com)
- Vitamins B6, B12 and folic acid contribute to the normal function of the immune system. (evonutrition.com)
Derivatives3
- Aminobenzoic acids their derivatives are important for the preparation of other pharmaceutical products, dyes, flavors, and preservatives. (plantmedia.com)
- The unexplored bioactives belonging to the class of glycosides, flavones, xanthones, organic acids and other phenolic derivatives. (derpharmachemica.com)
- This compound belongs to the class of organic compounds known as tetrahydrofolic acids and derivatives. (drugbank.com)
Methyl2
- N-Methyl-2-pyrrolidinone(NMP) CAS 872-50-4 Buy N-Methyl-2-Pyrrolidinone(NMP) 99.9% CAS 872-50-4 from AECOCHEM, Your reliable partner in China N-Methyl-2-Pyrrolidinone(NMP) suppliers, factory & manufacturers. (aecochemical.com)
- Dissolve the sample in water, add 0.1 ml of methyl red solution, and titrate with 0.1 M hydrochloric acid until a red colour is obtained. (pharmacy180.com)
Aminosalicylic Acid1
- The abilities of liver cytosol fractions from the suncus and Sprague-Dawley (SD) rats to N-acetylate aniline, p-aminobenzoic acid, p-aminosalicylic acid and 2-aminofluorene (AF) were compared. (elsevier.com)
Ester1
- It contains a 4-carboxylic acid ester-substituted imidazole moiety, which is also present in a number of compounds that are structural variants of the triazolo and imidazolo benzodiazepines. (pharmacy180.com)
Synthesis1
- It plays a role as a plant growth regulator and an intermediate in the synthesis of tetrahydrofolic acid in a wide range of organisms such as bacteria and fungi. (zellx.de)
Organic2
- RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (noaa.gov)
- the properties of permeability and also the organic composition of its substrate 4-7 . (bvsalud.org)
Niacin1
- Together with vitamins B6, B12, B3 (niacin) and pantothenic acid help contribute to normal energy release and the reduction of tiredness and fatigue. (evonutrition.com)
Ingredient1
- The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in SUNSCREENS . (bvsalud.org)
Sodium2
- Salicylic acid salts (potassium, sodium and triethanolamine). (science.org.au)
- Dissolve the substance in methanol and add 1.0 ml of 0.1 M hydrochloric acid, and perform potentiometric titration, using 0.1 M sodium hydroxide. (pharmacy180.com)
Acetic2
- The studied of reaction of the oxidation of 4-aminotoluene ozone in acetic acid. (kharkov.ua)
- Dissolve the sample in anhydrous acetic acid and add aceticanhydride, titrate with 0.1 M perchloric acid and determine the end point potentiometrically. (pharmacy180.com)
Reactions1
- 4-Aminobenzoic_acid = 55 reactions were found. (tu-bs.de)
Chloroform1
- Dissolve the sample in water, add 2 ml of dilute sulphuric acid, and shake with chloroform. (pharmacy180.com)
Suppliers2
- o-Toluidine CAS 95-53-4 Buy o-Toluidine 99% CAS 95-53-4 from AECOCHEM, Your reliable partner in China o-Toluidine suppliers, factory & manufacturers. (aecochemical.com)
- Methacrylic acid(MAA) CAS 79-41-4 Buy Methacrylic acid 99.9% CAS 79-41-4 from AECOCHEM, Your reliable partner in China Methacrylic acid suppliers, factory & manufacturers. (aecochemical.com)
Donor1
- A molecular entity capable of accepting a hydron from a donor (Br o nsted acid). (ebi.ac.uk)
Bacteria1
- Assists growth of lactic and butyric acid bacteria. (dormer.com)
Synonyms2
- Dibucaine hydrochloride Dibucaine hydrochloride Synonyms: 2-butoxy-n-(2-(diethylamino)ethyl)-4-quinolinecarboxamidmonoh. (biosteroids.com)
- Dibucaine hydrochloride Dibucaine hydrochloride Synonyms: 2-butoxy-n-(2-(diethylamino)ethyl)-4. (biosteroids.com)
Biotin1
- Vitamins in the human body are not synthesized in such quantities as to meet physiological needs (in small quantities Escherichia coli, bifidobacteria and lactobacilli perform vitamin-forming function, participating in the synthesis and absorption of vitamin K and B vitamins, including thiamine riboflavin, nicotinic and pantothenic, as well as folic acids, pyridoxine, biotin, cyanocobalamin). (kiev.ua)
Procaine1
- Procaine is a substituted aniline and a tertiary amino compound, which derives from a 2-diethylaminoethanol and a 4-aminobenzoic acid. (whmulei.com)
Attached to the benzene2
- These are benzoic acids containing an amine group attached to the benzene moiety. (foodb.ca)
- Derivatives of BENZOIC ACID that contain one or more amino groups attached to the benzene ring structure. (lookformedical.com)
Nicotinic4
- The ligand was prepared by refluxing nicotinic acid hydrazide and 3-bromobenzaldehyde in ethanol, the complexes were synthezed by mixing ethanolic solutions of the metal salts with the hydrazone. (ikppress.org)
- Complexes of nicotinic and isonicotinic acid hydrazides with Ba2+, Pb2+ and VO2+ salts. (ikppress.org)
- Complexes of copper (II) with some hydrazones derived from nicotinic and isonicotinic acid hydrazides. (ikppress.org)
- A cerium(III) complex, [Ce2(NA)6(H2O)4] (1) and anerbium(III) complex, [Er2(2- AMB)6(H2O)4]∙3H2O (2), where NA = nicotinic acid and 2-AMB =2-aminobenzoic acid, have been prepared and characterized by IR spectroscopy, thermogravimetric analysis and X-ray crystallography. (lboro.ac.uk)
Benzene4
- Objectives: We focused on 1,2,4-benzenetriol (BT), a benzene metabolite that generates reactive oxygen species (ROS) by autoxidation, to investigate the toxicity of benzene leading to leukemogenesis. (nih.gov)
- Alternatively, by nonenzymatic rearrangement, benzene oxide is converted to phenol, which can be oxidized by CYP2E1 to 1,4-hydroquinone (HQ) and 1,4-benzoquinone ( Snyder and Hedli 1996 ). (nih.gov)
- Benzoic acids , salts, or esters that contain an amino group attached to carbon number 2 or 6 of the benzene ring structure. (lookformedical.com)
- Linear Alkyl Benzene Sulfonic Acid. (chemicalstore.com)
Aromatic6
- In particular, amino acids containing an aromatic bridge also show marked optical changes in the presence of potencies. (nih.gov)
- Four pairs of isomeric aromatic heterocyclic dyes 1 - 8, synthesized from the diazotization and subsequent coupling reactions between 4 or 2-aminobenzoic acid as the diazo component and different N-substituted pyridone precursors as the coupling component, have been characterized and compared including UV-Vis and 1H NMR spectra, X-ray single-crystal structures and related DFT computations. (idexlab.com)
- 4-Aminobenzoic acid and 2-aminobenzoic acid have been used as the diazo components to couple with different N-substituted pyridone precursors to produce four pairs of isomeric aromatic heterocyclic dyes, for which 1H NMR spectral, UV-Vis spectral and single-crystal structural comparisons have been made. (idexlab.com)
- Para tertiary butylphenol or 4-tert-butylphenol is an organic aromatic compound, specifically a substituted phenol. (madhuchemicals.co.in)
- Carboxylic acids can be saturated, unsaturated, or aromatic. (lookformedical.com)
- Aniline substitution happened selectively at 1062368-49-3 IC50 placement 4 through nucleophilic aromatic substitution (System 1). (bibr-1048.info)
Hydrazide3
- We also investigated how the cellular effects of BT were modified by hydrogen peroxide (H 2 O 2 ) scavenger catalase, hypochlorous acid (HOCl) scavenger methionine, and 4-aminobenzoic acid hydrazide (ABAH), a myeloperoxidase (MPO)-specific inhibitor. (nih.gov)
- Syed ST, Radha E. Synthesis, characterization and antimicrobial activity of transition metal complexes of schiff base derivatives from isonicotinic acid hydrazide. (ikppress.org)
- Preparation and spectroscopic characterization of 2-ethoxy isobutryl acid hydrazide and 2-ethoxy isobutrylacetohydrazone and its metal complexes with Co(II), Ni(II) and Cu(II). (ikppress.org)
SUNSCREENS1
- The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in SUNSCREENS . (nih.gov)
Fatty Acids4
- This group of compounds includes amino acids and fatty acids . (lookformedical.com)
- B-2 also is involved in the catabolism (breakdown) of fatty acids. (myshopify.com)
- Vitamin B-5 is a precursor to Coenzyme A which, in turn is involved in the synthesis/production of amino acids, fatty acids, ketone bodies ,cholesterol steroid hormones, and neurotransmitters (specifically acetylcholine). (myshopify.com)
- Scalar Light assembles and maintains the molecular bonds of all essential earth elements transmuting them into essential nutrients, minerals , and fatty acids, fortifying the entire body-mind-soul system. (scalarlight.com)
Salts6
- Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure. (lookformedical.com)
- Salts and esters of hippuric acid. (lookformedical.com)
- The salts or esters of salicylic acids , or salicylate esters of an organic acid. (lookformedical.com)
- Included under this heading are a variety of acid forms, salts, esters, and amides that contain the benzeneacetic acid structure. (lookformedical.com)
- solution) with 4-bromo-, 4-nitro-, and 4-carboxybenzenediazonium tetrafluoroborate salts in order to find conditions for maximum sel. (datapdf.com)
- Here we examine the reactions of electric arc produced CNTs (dispersed by a variety of surfactants and polymers in aqueous solution) with 4-bromo-, 4-nitro-, and 4-carboxybenzenediazonium tetrafluoroborate salts in order to find conditions for maximum selectivity. (datapdf.com)
Synthesis6
- Savanini L, Chiasserini L, Gaeta A, Pellerano C. Synthesis and anti-tubercular evaluation of 4-quinolylhydrazones. (ikppress.org)
- An efficient and convenient method for the synthesis of 6-(1′,2′,3′-triazol-2′-yl) pyridine-3-carboxylic acid (1) via N -arylation is described. (innspub.net)
- Synthesis of novel bioactive phthalimido-4-methyl pentanoateorganotin (IV) esters with spectroscopic investigation. (innspub.net)
- Impairment of thymidylate synthesis in patients with folic acid deficiency is thought to account for the defective deoxyribonucleic acid (DNA) synthesis that leads to megaloblast formation and megaloblastic and macrocytic anemias. (nih.gov)
- Unnatural Amino Acids - Sigma-Aldrich · PDF fileUnnatural Amino Acids Vol. 8, No. 7 (R)-Allylalanine: a versatile α,α-disubstituted amino acid for peptide synthesis. (fdocument.org)
- B-5 is involved in the metabolism of amino acids and lipids (fats), hemoglobin and in the synthesis of neurotransmitters (specifically nor-epinephrine, epinephrine and dopamine). (myshopify.com)
Butyl1
- Now, our Weifang base can annually produce 4,000 tons of 2-Amino benzoic acid, 2,000 tons of 2,2'-Dithiosalicylic acid (DTSA), 2,000 tons of Isatoic anhydride(dtbc) and 2,000 tons of Methyl anthranilate/ethyl anthranilate/butyl anthranilate. (sunlionchem.com)
Acetic Acid2
- Produce pharmaceuticals acetic acid and bile iodobenzene shadow acid reagents. (sunttoncn.com)
- Acetic acid, glacial, Ethanoic. (chemkits.eu)
Phenyl3
- However, different intramolecular and intermolecular hydrogen bonding interactions are observed because of the introduction of an electron-withdrawing carboxylic acid group at the ortho or para position in the phenyl ring. (idexlab.com)
- It was found that the Schiff base of thiadiazole-1,3,4-(Dimethylamino)benzylidineamino]- [4-2-phenyl]amino was effective in reducing the size and density of malignant cells. (preprints.org)
- Yoshihara S and Ohta S 1998) Involvement of hepatic aldehyde oxidase in conversion of 1-methyl-4-phenyl-2,3-dihydropyridinium MPDP) to1-methyl-4-phenyl- 5,6-dihydro-2-pyri- done. (forexinfolink.com)
Intermediates1
- Phenylacetic acid The clinical trial International Study of Phase 3 IV RigosErtib, or INSPIRE, was finalized following guidance received from the U.S. Food and Drug Administration and European Medicines Agency.Under the terms of the agreement, ICIG will purchase substantially all of the pharmaceutical intermediates business, excluding the drug delivery technologies portion of the business. (brenlabs.com)
Derivative1
- The effect of (1, 3, 4-thiadiazole derivative) on the activity of malignant cells was studied by using different types of cell lines [Breast cancer, and human prostate cancer]. (preprints.org)
Folate4
- 8. Characterization of the role of para-aminobenzoic acid biosynthesis in folate production by Lactococcus lactis. (nih.gov)
- 13. Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis. (nih.gov)
- Folic acid is readily soluble in dilute solutions of alkali hydroxides and carbonates, and solutions of the drug may be prepared with the aid of sodium hydroxide or sodium carbonate, thereby forming the soluble sodium salt of folic acid (sodium folate). (nih.gov)
- Folic acid is metabolized in the liver to 7, 8-dihydrofolic acid and eventually to 5, 6, 7, 8-tetrahydrofolic acid with the aid of reduced diphosphopyridine nucleotide (DPNH) and folate reductases. (nih.gov)
Esters2
- The great amount of adipic acid produced annually is used as monomer for the production of nylon by a polycondensation reaction with hexamethylene diamine forming 6,6-nylon.Other major applications also involve polymers: it is a monomer for production of Polyurethane and its esters are plasticizers, especially in PVC. (chemkits.eu)
- Benzoic acid or benzoic acid esters substituted with one or more nitro groups. (lookformedical.com)
Amino acid2
- Commonly added at the suggested g/L to a nitrogen source, sugar, and amino acid mixture. (sunrisescience.com)
- Considering it is an indispensable part of building protein, and nowadays people are attaching increasing importance to fitness, there is a huge need for amino acid supplements powder in the market. (initialnaturals.com)
Oleic Acid1
- Oleic acid is often used for making special soaps and as soldering flux for soldering lead came and lead parts. (chemicalstore.com)
Lactic Acid13
- They use great ingredients like squalene (a good retinol substitute) and lactic acid (a safe acid) in their products which make them super effective. (simplyandreea.com)
- Sunday Riley - Good Genes All-In-One Lactic Acid Treatment is fine to use, but make sure to avoid their retinoids! (simplyandreea.com)
- Lactic acid has great potential as a precursor for the production of bioplastics alternatives to conventional plastics. (biomedcentral.com)
- Efficient lactic acid fermentation from non-food lignocellulosic substrates requires pretreatment and saccharification to generate fermentable sugars. (biomedcentral.com)
- A fermentation process that requires little to no enzyme additions, i.e. consolidated bioprocessing would be preferred and requires lactic acid-producing organisms that have cellulolytic and/or hemicellulolytic activity. (biomedcentral.com)
- Subsequent screening for lactic acid production was carried out from C6 and C5 sugar fermentations and a selection of the best lactic acid producers was made. (biomedcentral.com)
- In fermentations on a mixture of glucose and xylose, a total of 20.3 g of lactic acid was produced with a yield of 0.94 g product/g sugar consumed. (biomedcentral.com)
- In addition, strain T12 is capable of direct conversion of beech wood xylan to mainly lactic acid in minimal media. (biomedcentral.com)
- We have demonstrated that G. thermodenitrificans T12 is genetically accessible and produces lactic acid as its main fermentation product on glucose, xylose and a mixture thereof. (biomedcentral.com)
- Strain T12 was additionally used for the direct conversion of xylan to lactic acid. (biomedcentral.com)
- The genetic accessibility of the T12 strain provides a solid basis for the development of this strain into a host for consolidated bioprocessing of biomass to lactic acid. (biomedcentral.com)
- Lactic acid is an organic acid that can be used as building block for poly lactic acid (PLA) [ 2 ]. (biomedcentral.com)
- Petrochemically produced lactic acid always yields a racemic mixture of both d - and l -lactic acid which results in a lower thermostability of the PLA polymer in comparison to its optically pure counterpart derived from microbial production. (biomedcentral.com)
Anthranilic acid4
- Recent Examples on the Web The blue fluorescence, seen only when the worms are under ultraviolet light, comes from anthranilic acid , an organic compound produced inside little granules that line the worm's intestine. (merriam-webster.com)
- Christopher Crockett, Scientific American , 2 Aug. 2013 The drop in pH amplifies the anthranilic acid 's natural fluorescence, generating a blue flash that follows the calcium wave. (merriam-webster.com)
- Christopher Crockett, Scientific American , 2 Aug. 2013 This initial investigation led them to the discovery that the anthranilic acid fluoresces and the calcium wave triggers the event. (merriam-webster.com)
- These example sentences are selected automatically from various online news sources to reflect current usage of the word 'anthranilic acid. (merriam-webster.com)
Ascorbic3
- Ascorbic Acid (C) ... 15 mgs. (nih.gov)
- Ascorbic acid also known as vitamin C is a strong anti ocidant used in production of pharmaceutical or as an additive to certain foods. (chemicalstore.com)
- Ascorbic acid is soluble in many alcohols including propylene glycol, glycerin and isopropyl alcohol. (chemicalstore.com)
Complexes2
- Infrared Multiple Photon Dissociation Spectra of Sodiated Complexes of the Aliphatic Amino Acids. (utah.edu)
- Each pack (11 tablets) contains a synergistic combination of mineral complexes, lipotropics, digestive enzymes, branched-chain amino acids, and pre-workout energizers. (puritan.com)
Metabolism1
- Their lack increases the sensitivity of the human body to the ionizing radiation, effect because the products of radiolysis disrupt the processes of utilization and metabolism of vitamins, their conversion into coenzyme forms, combination with apoenzymes and their absorption in the intestine [4, 5]. (kiev.ua)
Powder2
- Folic acid occurs as a yellow or yellowish-orange crystalline powder and is very slightly soluble in water and insoluble in alcohol. (nih.gov)
- We manufacture amino acids powder, an organic compound, and you can purchase them as a dietary supplement. (initialnaturals.com)
Inorganic1
- Inorganic compounds derived from hydrochloric acid that contain the Cl- ion. (lookformedical.com)
Organic compounds1
- Amino acids are organic compounds that combine to form proteins. (initialnaturals.com)
Folic acid defic1
- Vitamin B12 deficiency (eg, pernicious anemia), folic acid deficiency, and certain medications are the most common causes of megaloblastic anemia, a macrocytic anemia. (medscape.com)
Mandelic1
- Sub for glycolic, lactic, and mandelic acids (AHAs) that are all considered safe for pregnancy use. (simplyandreea.com)
Zinc1
- Three zinc(II) and one copper(II) coordination compounds with 4-aminobenzoic acid (HL) have been described. (uni-lj.si)
Vitamin3
- For several decades now, doctors and public health experts have been recommending that all women of child bearing age ensure that they get enough folic acid (Vitamin B9) through fortified foods and dietary supplements to protect against birth defects should they become pregnant. (fairhavenhealth.com)
- But, before your body can utilize folic acid, it must be converted to methylfolate - the bioactive form of Vitamin B9 that is used in the body for many vital processes and reactions. (fairhavenhealth.com)
- In gene transcription vitamin A, as retinoic acid, is converted into retinol, which is taken up by a cell, oxidized into retinal (by relevant enzymes). (myshopify.com)
Purity1
- While high purity sulfuric acid is clear, our product is technical grade and may be cloudy and amber color. (chemicalstore.com)
Sodium Salt1
- It may also be viewed as the sodium salt of hypochlorous acid. (madhuchemicals.co.in)
Biomarker2
GLUTAMIC ACID1
- An aminobenzoic acid isomer that combines with pteridine and GLUTAMIC ACID to form FOLIC ACID . (nih.gov)