A non-penetrating amino reagent (commonly called SITS) which acts as an inhibitor of anion transport in erythrocytes and other cells.
An inhibitor of anion conductance including band 3-mediated anion transport.
A class of organic compounds that contains a naphthalene moiety linked to a sulfonic acid salt or ester.
A subclass of purinergic P2 receptors that signal by means of a ligand-gated ion channel. They are comprised of three P2X subunits which can be identical (homotrimeric form) or dissimilar (heterotrimeric form).
Compounds that bind to and block the stimulation of PURINERGIC P2 RECEPTORS.
This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
A class of cell surface receptors for PURINES that prefer ATP or ADP over ADENOSINE. P2 purinergic receptors are widespread in the periphery and in the central and peripheral nervous system.
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
A colorimetric reagent for iron, manganese, titanium, molybdenum, and complexes of zirconium. (From Merck Index, 11th ed)
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
Organic compounds that contain 1,2-diphenylethylene as a functional group.
Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.
The composition, conformation, and properties of atoms and molecules, and their reaction and interaction processes.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
Derivatives of acetamide that are used as solvents, as mild irritants, and in organic synthesis.
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
The N-acetyl derivative of galactosamine.
Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The N-acetyl derivative of glucosamine.
Membrane transporters that co-transport two or more dissimilar molecules in the opposite direction across a membrane. Usually the transport of one ion or molecule is against its electrochemical gradient and is "powered" by the movement of another ion or molecule with its electrochemical gradient.
The sequence of carbohydrates within POLYSACCHARIDES; GLYCOPROTEINS; and GLYCOLIPIDS.
The characteristic 3-dimensional shape of a carbohydrate.
Protein or glycoprotein substances of plant origin that bind to sugar moieties in cell walls or membranes. Some carbohydrate-metabolizing proteins (ENZYMES) from PLANTS also bind to carbohydrates, however they are not considered lectins. Many plant lectins change the physiology of the membrane of BLOOD CELLS to cause agglutination, mitosis, or other biochemical changes. They may play a role in plant defense mechanisms.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
Carbohydrates consisting of between two (DISACCHARIDES) and ten MONOSACCHARIDES connected by either an alpha- or beta-glycosidic link. They are found throughout nature in both the free and bound form.
The giving of drugs, chemicals, or other substances by mouth.
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.
The rate dynamics in chemical or physical systems.
Substances that reduce the growth or reproduction of BACTERIA.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
... disulfonic acid MeSH D02.455.426.559.389.150.700.075 - bibenzyls MeSH D02.455.426.559.389.150.700.100 - chlorotrianisene MeSH ... isothiocyanatostilbene-2,2'-disulfonic acid MeSH D02.500.375.125 - 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid MeSH ... quinic acid MeSH D02.241.511.852 - shikimic acid MeSH D02.241.511.902 - sugar acids MeSH D02.241.511.902.107 - ascorbic acid ... edetic acid MeSH D02.241.081.038.455 - egtazic acid MeSH D02.241.081.038.581 - iodoacetic acid MeSH D02.241.081.038.581.400 - ...
... disulfonic Acid 26% * Arteries 25% * Emergencies 23% * Cerebral Hemorrhage 22% * Oral Pathology 22% ... isothiocyanatostilbene-2,2- ...
... disulfonic Acid Medicine & Life Sciences 73% * Cell Membrane Potential Chemical Compounds 59% ... isothiocyanatostilbene-2,2- ... 4 mV to 14±3 mV. The results suggest: (i) In the diluting ... This cell-voltage response was totally abolished by 10-3 mol/l SITS and significantly reduced by 10-4 mol/l acetazolamide or by ... This cell-voltage response was totally abolished by 10-3 mol/l SITS and significantly reduced by 10-4 mol/l acetazolamide or by ...
DISULFONIC ACID. Guna-dermo (Salt/Mix). AB00053279. HMS3370J20. AC1Q4F1X. I10-0345. Acetamide, N-[2-(5-methoxy-1H-indol-3-yl) ... ISOTHIO-CYANATOSTILBENE-2,2- ... N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide. Molecular weight ... Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-(9CI). J10164. Acetamide, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-}. KBioGR_ ... Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)- (9CI). IN1244. Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-(6CI,8CI). KBio3_ ...
... disulfonic Acid Medicine & Life Sciences 100% * Heart Rate Medicine & Life Sciences 69% ... isothiocyanatostilbene-2,2- ... Moreover, in CO2/HCO3--superfused muscles pretreated with SITS ... 4, 01.01.1996, p. 698-704.. Research output: Contribution to journal › Article › peer-review ... 2,7-bis-(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester Medicine & Life Sciences 56% ...
... disulfonic acid MeSH D02.455.426.559.389.150.700.075 - bibenzyls MeSH D02.455.426.559.389.150.700.100 - chlorotrianisene MeSH ... isothiocyanatostilbene-2,2-disulfonic acid MeSH D02.500.375.125 - 4,4-diisothiocyanostilbene-2,2-disulfonic acid MeSH ... quinic acid MeSH D02.241.511.852 - shikimic acid MeSH D02.241.511.902 - sugar acids MeSH D02.241.511.902.107 - ascorbic acid ... edetic acid MeSH D02.241.081.038.455 - egtazic acid MeSH D02.241.081.038.581 - iodoacetic acid MeSH D02.241.081.038.581.400 - ...
We also Provide Trading Suppliers & Manufacture for 27816-36-0 2-CHLOROPROPIONAMIDE. ... disulfonic Acid * 27816-82-6 3,4-DICHLOROPHENYLACETANILIDE * 27816-91-7 N-[4-(methylsulfanyl)phenyl]-3-phenylpropanamide ... isothiocyanatostilbene-2,2- ... Propanamide, 2-chloro-. Cas No: 27816-36-0. No Data. No Data. ... Propanamide, 2-chloro-. Cas No: 27816-36-0. No Data. No Data. No Data. Henan Tianfu Chemical Co., Ltd.. Contact Supplier ...
... exchange activity that was inhibited by DIDS but not by dibenzamidostilbene disulfonic acid (DBDS). AT-1 cell Cl(-)/HCO(3)(-) ... disulfonic Acid);酸碱平衡(Acid-Base Equilibrium);腺苷三磷酸(Adenosine Triphosphate);血管紧张素Ⅱ(Angiotensin II);动物(Animals);阴离子转运蛋白质类(Anion ... isothiocyanatostilbene-2,2- ... Disulfonic Acid);4-乙酰氨基-4-异氰酸芪-2,2-二磺酸(4-Acetamido-4- ... exchange activity that was inhibited by DIDS but not by dibenzamidostilbene
... disulfonic acid (SITS). The density of the Ca(2+)-activated chloride currents (I(Cl,Ca)) in left ventricular myocytes was ... APD alternans was suppressed by adding 1 microM ryanodine, 100 microM 4,4-diisothiocyanostilbene-2,2-disulfonic acid (DIDS), ... disulfonic acid (SITS). The density of the Ca(2+)-activated chloride currents (I(Cl,Ca)) in left ventricular myocytes was ... disulfonic acid (DIDS), and 100 microM 4-acetamido-4-isothiocyanostilbene-2,2- ...
... disulfonic Acid/analogs & derivatives; Allyl Compounds; Animals; Butanones/metabolism; Carcinogenesis; Carcinogens/metabolism; ... isothiocyanatostilbene-2,2- ... and its derivatives like nicotinamide and nicotinic acid. RNA- ... NNK drives metabolic changes including mitochondrial tricarboxylic acid (TCA) metabolites and pathways including Nicotine ... In this study, we treated the female A/J mice with CS carcinogen 4-[methyl(nitroso)amino]-1-(3-pyridinyl)-1-butanone (NNK) and ...
... disulfonic Acid, Disodium Salt Preferred Term Term UI T414318. Date05/15/2000. LexicalTag NON. ThesaurusID NLM (2001). ... isothiocyanatostilbene-2,2-disulfonic Acid Preferred Term Term UI T037911. Date05/12/1981. LexicalTag NON. ThesaurusID UNK ( ... disulfonic Acid, Disodium Salt Narrower Concept UI. M0329725. Registry Number. 51023-76-8. Terms. 4-Acetamido-4- ... disulfonic Acid Preferred Concept UI. M0019908. Registry Number. 27816-59-7. Related Numbers. 51023-76-8. Scope Note. A non- ...
... disulfonic Acid, Disodium Salt Preferred Term Term UI T414318. Date05/15/2000. LexicalTag NON. ThesaurusID NLM (2001). ... isothiocyanatostilbene-2,2-disulfonic Acid Preferred Term Term UI T037911. Date05/12/1981. LexicalTag NON. ThesaurusID UNK ( ... disulfonic Acid, Disodium Salt Narrower Concept UI. M0329725. Registry Number. 51023-76-8. Terms. 4-Acetamido-4- ... disulfonic Acid Preferred Concept UI. M0019908. Registry Number. 27816-59-7. Related Numbers. 51023-76-8. Scope Note. A non- ...
Disulfonic Acid N0000167056 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine N0000167084 4-(3-Butoxy-4- ... isothiocyanatostilbene-2,2-disulfonic Acid N0000006481 4-Aminobenzoic Acid N0000168376 4-Aminobutyrate Transaminase ... Neutral N0000006806 Amino Acids N0000011372 Amino Acids, Acidic N0000011248 Amino Acids, Aromatic N0000011332 Amino Acids, ... Acyclic N0000008269 Acids, Aldehydic N0000007628 Acids, Carbocyclic N0000007629 Acids, Heterocyclic N0000007630 Acids, ...
Excitatory amino acids have different effects on horizontal cells in eyecup and isolated retina. Miyachi, E. I., Lukasiewicz, P ... Margolis, T., Irvine, A. R., Hoyt, W. F. & Hyman, R., Jan 1 1988, In: Ophthalmology. 95, 7, p. 937-940 4 p.. Research output: ... Huang, A. J. W., Watson, B. D., Hernandez, E. & Tseng, S. C. G., 1988, In: Ophthalmology. 95, 2, p. 228-235 8 p.. Research ... Kass, M. A., Gordon, M., Morley, R. E., Meltzer, D. W. & Goldberg, J. J., 1987, In: American journal of ophthalmology. 103, 2, ...
... disulfonic Acid) Skull Base Neoplasms C4.588.443.840.830 Skull Neoplasms C4.588.443.840 Sleep Disorders, Circadian Rhythm ... isothiocyanatostilbene-2,2- ... Disulfonic Acid) Diffusion Chambers, Culture E5.909.262.387 ... E5.393.760.705.685 Periodic Acid-Schiff Reaction E5.909.262.607.790 E5.200.500.607.790 E5.909.262.620.670.620 E5.200.500.620. ... Replaced for 2001 by Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester) Erythroblasts A11.118.413.350.200 A11.118. ...
Disulfonic Acid. *4-Acetamido-4-isothiocyanatostilbene-2,2-disulfonic Acid. *Bibenzyls ...
... disulfonic Acid / analogs & derivatives Actions. * Search in PubMed * Search in MeSH ... isothiocyanatostilbene-2,2- ... Figure 2.. Mean Aggregate Quality Score and Mean Quality Bonus ... Figure 2.. Mean Aggregate Quality Score and Mean Quality Bonus Payment (QBP) for Plans in Puerto Rico and the US Mainland From ... 2 Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.. *3 Department of Health Care Policy, ...
... disulfonic acid derivatives. Representative acceptor fluorescent moieties, depending upon the donor fluorescent moiety used, ... isothio- cyanatostilbene-2, 2-disulfonic acid, 7-diethylamino-3- (4-isothiocyanatophenyl)-4- methylcoumarin, succinimdyl 1- ... Preferably, the target nucleic acids are on the same membrane. A nucleic acid molecule is deemed to hybridize to nucleic acids ... Positive control samples can amplify a nucleic acid control template (e. g., a nucleic acid other than the target nucleic acid ...
Disulfonic Acid 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone 4- ... isothiocyanatostilbene-2,2-disulfonic Acid 4-Aminobenzoic Acid 4-Aminobutyrate Transaminase 4-Aminopyridine 4-Butyrolactone 4- ... Amino Acids Amino Acids, Acidic Amino Acids, Aromatic Amino Acids, Basic Amino Acids, Branched-Chain Amino Acids, Cyclic Amino ... Acid Ceramidase Acid Etching, Dental Acid Phosphatase Acid Rain Acid Sensing Ion Channel Blockers Acid Sensing Ion Channels ...
  • This cell-voltage response was totally abolished by 10 -3 mol/l SITS and significantly reduced by 10 -4 mol/l acetazolamide or by omission of Na + from the extracellular perfusate. (mssm.edu)
  • Cultured AT-1 cells exhibited a substantial basal Na(+)-independent Cl(-)/HCO(3)(-) (but not Cl(-)/OH(-)) exchange activity that was inhibited by DIDS but not by dibenzamidostilbene disulfonic acid (DBDS). (wanfangdata.com.cn)
  • APD alternans was suppressed by adding 1 microM ryanodine, 100 microM 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), and 100 microM 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid (SITS). (pcom.edu)
  • Tobacco carcinogen 4-[methyl(nitroso)amino]-1-(3-pyridinyl)-1-butanone (NNK) drives metabolic rewiring and epigenetic reprograming in A/J mice lung cancer model and prevention with diallyl sulphide (DAS). (nih.gov)
  • In this study, we treated the female A/J mice with CS carcinogen 4-[methyl(nitroso)amino]-1-(3-pyridinyl)-1-butanone (NNK) and naturally occurring organosulphur compound, diallyl sulphide (DAS) for 2 and 4 weeks after NNK injection and examined the metabolomic and DNA CpG methylomic and RNA transcriptomic profiles in the lung tissues. (nih.gov)