3-Oxoacyl-(Acyl-Carrier-Protein) Synthase: An enzyme of long-chain fatty acid synthesis, that adds a two-carbon unit from malonyl-(acyl carrier protein) to another molecule of fatty acyl-(acyl carrier protein), giving a beta-ketoacyl-(acyl carrier protein) with the release of carbon dioxide. EC 2.3.1.41.Acyl Carrier Protein: Consists of a polypeptide chain and 4'-phosphopantetheine linked to a serine residue by a phosphodiester bond. Acyl groups are bound as thiol esters to the pantothenyl group. Acyl carrier protein is involved in every step of fatty acid synthesis by the cytoplasmic system.Transferases (Other Substituted Phosphate Groups): A class of enzymes that transfers substituted phosphate groups. EC 2.7.8.Cerulenin: An epoxydodecadienamide isolated from several species, including ACREMONIUM, Acrocylindrum, and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.Pantetheine: An intermediate in the pathway of coenzyme A formation in mammalian liver and some microorganisms.Fatty Acids: Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)Fatty Acid Synthases: Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives.Acyltransferases: Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor, forming either esters or amides. (From Enzyme Nomenclature 1992) EC 2.3.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Fatty Acid Synthase, Type II: The form of fatty acid synthase complex found in BACTERIA; FUNGI; and PLANTS. Catalytic steps are like the animal form but the protein structure is different with dissociated enzymes encoded by separate genes. It is a target of some ANTI-INFECTIVE AGENTS which result in disruption of the CELL MEMBRANE and CELL WALL.ThiophenesPolyketide Synthases: Large enzyme complexes composed of a number of component enzymes that are found in STREPTOMYCES which biosynthesize MACROLIDES and other polyketides.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Acyl-Carrier Protein S-Malonyltransferase: This enzyme catalyzes the transacylation of malonate from MALONYL CoA to activated holo-ACP, to generate malonyl-(acyl-carrier protein), which is an elongation substrate in FATTY ACIDS biosynthesis. It is an essential enzyme in the biosynthesis of FATTY ACIDS in all BACTERIA.3-Oxoacyl-(Acyl-Carrier-Protein) Reductase: A 3-oxoacyl reductase that has specificity for ACYL CARRIER PROTEIN-derived FATTY ACIDS.Substrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Bacterial Proteins: Proteins found in any species of bacterium.Coenzyme ACrystallography, X-Ray: The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Pantothenic Acid: A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Genetic Complementation Test: A test used to determine whether or not complementation (compensation in the form of dominance) will occur in a cell with a given mutant phenotype when another mutant genome, encoding the same mutant phenotype, is introduced into that cell.Enoyl-(Acyl-Carrier-Protein) Reductase (NADH): An NAD-dependent enzyme that catalyzes the oxidation of acyl-[acyl-carrier protein] to trans-2,3-dehydroacyl-[acyl-carrier protein]. It has a preference for acyl groups with a carbon chain length between 4 to 16.Carbon-Sulfur Ligases: Enzymes that catalyze the joining of two molecules by the formation of a carbon-sulfur bond. EC 6.2.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Acylation: The addition of an organic acid radical into a molecule.Thiolester HydrolasesMalonyl Coenzyme A: A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.Isoenzymes: Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.Triclosan: A diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.Streptomyces: A genus of bacteria that form a nonfragmented aerial mycelium. Many species have been identified with some being pathogenic. This genus is responsible for producing a majority of the ANTI-BACTERIAL AGENTS of practical value.Saccharopolyspora: A genus of gram-positive bacteria whose spores are round to oval and covered by a sheath.Apoproteins: The protein components of a number of complexes, such as enzymes (APOENZYMES), ferritin (APOFERRITINS), or lipoproteins (APOLIPOPROTEINS).Acyl Coenzyme A: S-Acyl coenzyme A. Fatty acid coenzyme A derivatives that are involved in the biosynthesis and oxidation of fatty acids as well as in ceramide formation.Multienzyme Complexes: Systems of enzymes which function sequentially by catalyzing consecutive reactions linked by common metabolic intermediates. They may involve simply a transfer of water molecules or hydrogen atoms and may be associated with large supramolecular structures such as MITOCHONDRIA or RIBOSOMES.Anthraquinones: Compounds based on ANTHRACENES which contain two KETONES in any position. Substitutions can be in any position except on the ketone groups.Coriandrum: A plant genus of the family APIACEAE. The leaves are the source of cilantro and the seeds are the source of coriander, both of which are used in SPICES.Acyl-Carrier Protein S-Acetyltransferase: A enzyme that catalyzes the transfer of acetyl groups from ACETYL CoA to acyl-carrier protein to form COENZYME A and acetyl-acyl-carrier protein.MalonatesKinetics: The rate dynamics in chemical or physical systems.Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Lipid A: Lipid A is the biologically active component of lipopolysaccharides. It shows strong endotoxic activity and exhibits immunogenic properties.Acetyl Coenzyme A: Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.Peptide Synthases: Ligases that catalyze the joining of adjacent AMINO ACIDS by the formation of carbon-nitrogen bonds between their carboxylic acid groups and amine groups.Naphthacenes: Polyacenes with four ortho-fused benzene rings in a straight linear arrangement. This group is best known for the subclass called TETRACYCLINES.Protein Structure, Tertiary: The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Plants: Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.
... acyl-carrier-protein synthase activity]. • acyl-[acyl-carrier-protein hydrolase activity]. • hydrolase activity. • palmitoyl-[ ... fatty acid synthase activity. • myristoyl-[acyl-carrier-protein hydrolase activity]. • enoyl-[acyl-carrier-protein reductase ( ... acyl-carrier-protein dehydratase activity]. • protein homodimerization activity. • catalytic activity. • [acyl-carrier-protein ... identical protein binding. • oleoyl-[acyl-carrier-protein hydrolase activity]. • oxidoreductase activity. • 3-oxoacyl-[ ...
... acyl-carrier-protein] Thus, the two substrates of this enzyme are (Z)-hexadec-11-enoyl-[acyl-carrier-protein] and malonyl-[acyl ... The systematic name of this enzyme class is (Z)-hexadec-11-enoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-pr otein] C- ... acyl-carrier-protein], CO2, and acyl-carrier-protein. This enzyme belongs to the family of transferases, specifically those ... acyl-carrier-protein] + malonyl-[acyl-carrier-protein] ⇌ {\displaystyle \rightleftharpoons } (Z)-3-oxooctadec-13-enoyl-[acyl- ...
... acyl-carrier-protein] reductase, beta-hydroxyacyl-[acylcarrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase ... Fatty acid synthase. *Beta-ketoacyl-ACP synthase. *Β-Ketoacyl ACP reductase. *3-Hydroxyacyl ACP dehydrase ... Other names in common use include beta-ketoacyl-[acyl-carrier protein](ACP) reductase, beta-ketoacyl acyl carrier protein (ACP ... Prescott DJ, Vagelos PR (1972). "Acyl carrier protein". Adv. Enzymol. Relat. Areas Mol. Biol. 36: 269-311. doi:10.1002/ ...
... acyl-carrier-protein Thus, the two substrates of this enzyme are acyl-acyl-carrier-protein and malonyl-acyl-carrier-protein, ... acyl-malonyl(acyl-carrier-protein)-condensing enzyme, acyl-malonyl acyl carrier protein-condensing enzyme, beta-ketoacyl acyl ... The systematic name of this enzyme class is acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase ( ... beta-ketoacyl-acyl carrier protein synthetase, beta-ketoacyl-[acyl carrier protein] synthase, beta-ketoacylsynthase, condensing ...
... acyl-carrier-protein) synthase MeSH D08.811.913.050.625 --- phosphatidylcholine-sterol O-acyltransferase MeSH D08.811.913.050. ... acyl-carrier-protein) reductase (nadh) MeSH D08.811.682.660.390 --- enoyl-(acyl-carrier protein) reductase (nadph, b-specific) ... acyl-carrier protein s-acetyltransferase MeSH D08.811.913.050.134.060 --- acetyl-CoA C-acetyltransferase MeSH D08.811.913.050. ... acyl-carrier protein s-malonyltransferase MeSH D08.811.913.050.173 --- 1-acylglycerol-3-phosphate O-acyltransferase MeSH ...
... acyl-carrier-protein) synthase II EC 2.3.1.180: beta-ketoacyl-(acyl-carrier-protein) synthase III EC 2.3.1.181: lipoyl(octanoyl ... acyl-carrier-protein) S-acetyltransferase EC 2.3.1.39: (acyl-carrier-protein) S-malonyltransferase EC 2.3.1.40: acyl-(acyl- ... acyl-carrier protein) synthase EC 2.7.7.67: CDP-archaeol synthase EC 2.7.7.68: 2-phospho-L-lactate guanylyltransferase EC 2.7. ... acyl-carrier-protein) synthase EC 2.3.1.208: 4-hydroxycoumarin synthase EC 2.3.1.209: dTDP-4-amino-4,6-dideoxy-D-glucose ...
... acyl-carrier-protein) synthase III (FabH)". Biotechnology and Bioengineering. 112 (8): 1613-1622. doi:10.1002/bit.25583. ISSN ... acyl-carrier-protein) synthase III (FabH)". Biotechnology and Bioengineering. 112 (8): 1613-22. doi:10.1002/bit.25583. PMID ... and genetic studies of beta-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli". Journal of Biological ... "Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of ...
Price AC, Choi KH, Heath RJ, Li Z, White SW, Rock CO (March 2001). "Inhibition of beta-ketoacyl-acyl carrier protein synthases ... Middleton B (April 1973). "The oxoacyl-coenzyme A thiolases of animal tissues". Biochem. J. 132 (4): 717-30. PMC 1177647 . PMID ... Mammalian nonspecific lipid-transfer protein (nsL-TP) (also known as sterol carrier protein 2) is a protein which seems to ... or acyl carrier protein (ACP). All thiolases, whether they are biosynthetic or degradative in vivo, preferentially catalyze the ...
... acyl-carrier-protein) reductase (NADH) EC 1.3.1.10: enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific) EC 1.3.1.11: 2- ... pyruvate synthase EC 1.2.7.2: 2-oxobutyrate synthase EC 1.2.7.3: 2-oxoglutarate synthase EC 1.2.7.4: carbon-monoxide ... acyl-(acyl-carrier-protein) desaturase EC 1.14.19.3: linoleoyl-CoA desaturase EC 1.14.19.4: Delta8-fatty-acid desaturase EC ... long-chain acyl-(acyl-carrier-protein) reductase EC 1.2.1.81: sulfoacetaldehyde dehydrogenase (acylating) EC 1.2.1.82: beta-apo ...
The reaction proceeds as such: acyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] → a 3-oxoacyl-[acyl-carrier ... acyl-carrier protein] + CO2 + [acyl-carrier protein In Streptococcus pneumonia, for example, synthase II is used as an ... The reaction proceeds as such: (Z)-hexadec-11-enoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] → (Z)-3-oxooctadec- ... "BRENDA - Information on EC 2.3.1.41 - beta-ketoacyl-[acyl-carrier-protein] synthase I". www.brenda-enzymes.org. Retrieved 2016- ...
enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific) Ja 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Ja ... pyridoxal 5'-phosphate synthase Ja 1.4.3.13 protein-lysine 6-oxidase Ja ... Glycerol-3-fosfaatdehydrogenase (NAD+) Ja 1.1.1.9 Xylitol + NAD+ ⇌. {\displaystyle \rightleftharpoons }. D-xylulose + NADH + H+ ... R,R)-butaan-2,3-diol + NAD+ ⇌. {\displaystyle \rightleftharpoons }. (R)-Acetoïne + NADH + H+ (R,R)-butaanedioldehydrogenase ...
... acyl-carrier-protein synthase activity]. • acyl-[acyl-carrier-protein hydrolase activity]. • hydrolase activity. • palmitoyl-[ ... fatty acid synthase activity. • myristoyl-[acyl-carrier-protein hydrolase activity]. • enoyl-[acyl-carrier-protein reductase ( ... acyl-carrier-protein dehydratase activity]. • protein homodimerization activity. • catalytic activity. • [acyl-carrier-protein ... identical protein binding. • oleoyl-[acyl-carrier-protein hydrolase activity]. • oxidoreductase activity. • 3-oxoacyl-[ ...
... acyl-carrier-protein] reductase, beta-hydroxyacyl-[acylcarrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase ... Fatty acid synthase. *Beta-ketoacyl-ACP synthase. *Β-Ketoacyl ACP reductase. *3-Hydroxyacyl ACP dehydrase ... Other names in common use include beta-ketoacyl-[acyl-carrier protein](ACP) reductase, beta-ketoacyl acyl carrier protein (ACP ... Prescott DJ, Vagelos PR (1972). "Acyl carrier protein". Adv. Enzymol. Relat. Areas Mol. Biol. 36: 269-311. doi:10.1002/ ...
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex ... Acetyl-CoA + malonyl-[acyl-carrier-protein] = acetoacetyl-[acyl-carrier-protein] + CoA + CO2. UniProt ... Protein disorder predictions are based on JRONN (Troshin, P. and Barton, G. J. unpublished), a Java implementation of RONN * ... This protein in other organisms (by gene name): C5CAR9 - Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC ...
... acyl-carrier-protein] synthase 3. Q9F6D4. Details. Drug Relations. Drug Relations. DrugBank ID. Name. Drug group. ... acyl-carrier-protein] synthase 3. Details. Name. 3-oxoacyl-[acyl-carrier-protein] synthase 3. Kind. protein. Organism. ...
Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the ... Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP ... acyl-carrier-protein] synthase activity Source: InterPro. *beta-ketoacyl-acyl-carrier-protein synthase III activity Source: ... acyl-carrier-protein] synthase 3UniRule annotation. Manual assertion according to rulesi ...
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP ... acyl-carrier-protein] synthase 1 (EC:2.3.1.41*Search proteins in UniProtKB for this EC number. ... acyl-carrier-protein] synthase 1 OS=Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman) OX=652616 GN=kasA PE=2 SV ... acyl-carrier-protein] synthase 1. ). MYCTU. 416. Beta-ketoacyl-[acyl-carrier-protein] synthase II. Mycobacterium leprae 3125609 ...
... acyl-carrier-protein] synthase, mitochondrial. ... acyl-CoA metabolic process 30 medium-chain fatty acid ... acyl-carrier-protein] synthase, mitochondrial. Complete proteome 20,231 ...
... acyl-carrier-protein] synthase 3 - Escherichia coli (strain K12). Help ...
... acyl-carrier-protein] synthase 3. Prochlorococcus marinus (strain MIT 9515) ... acyl-carrier-protein (ACP)] synthase III. IPR013751PF08545. 246-334. 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C- ... acyl-carrier-protein] synthase 3 UniProtKBInterProSTRINGInteractive Modelling. 335 aa; Sequence (Fasta) ...
Acyl-Carrier-Protein) Synthase / metabolism * Actins * Animals * Antigens, Bacterial / genetics * Antigens, Bacterial / ... Thus, virulence-related protein secretion is localized in mycobacteria, suggesting new potential therapeutic targets, which are ...
... acyl-carrier-protein) synthase III. 0.253. 0.0013806. 0.52. 0.014. F-AGTTATCGGTGCAGAAGTTC, R-AAAGGGTGACGAAACAGC. ... Putative starch (bacterial glycogen) synthase. 12.283. 4.70E−06. SMU.935. Putative amino acid ABC transporter, permease protein ... Conserved hypothetical protein. 23.54. 3.40E−06. SMU.936. Putative amino acid ABC transporter, ATP-binding protein. 18.147. ... Hypothetical protein. 0.295. 0.0023821. SMU.1516. Putative histidine kinase CovS VicK homolog. 0.284. 0.0004549. 0.55. 0.017. F ...
... acyl-carrier-protein] synthase activity; IEA:HAMAP. DR GO; GO:0033818; F:beta-ketoacyl-acyl-carrier-protein synthase III ... acyl-carrier-protein] = CC acetoacetyl-[acyl-carrier-protein] + CoA + CO(2). CC -!- PATHWAY: Lipid metabolism; fatty acid ... acyl-carrier-protein] synthase III;AltName: DE Full=Beta-ketoacyl-ACP synthase III; (PROAS_1.PE1015). GN Name=fabH; ... acyl-carrier-protein] synthase 3; EC=2.3.1 DE 180;AltName: Full=3-oxoacyl-[ ...
... acyl carrier protein) synthase III, FabH (Xoo4209) from Xanthomonas oryzae pv. oryzae KACC10331 ... acyl carrier protein) synthase III, FabH (Xoo4209) from Xanthomonas oryzae pv. oryzae KACC10331; X-RAY DIFFRACTION 2.05 Å SMTL ... 3-oxoacyl-synthase III. Oligo-state. monomer. SMTL ID. 3fk5.2. Ligands. -. Polypeptides. 3-oxoacyl-synthase III. Oligo-state. ...
fabF; beta ketoacyl-acyl carrier protein synthase [KO:K09458] [EC:2.3.1.179] ... acyl carrier protein) synthase II [KO:K09458] [EC:2.3.1.179] ... envM; enoyl-[acyl-carrier-protein] reductase [KO:K00208] [EC: ... fabZ; (3R)-hydroxymyristol acyl carrier protein dehydrase [KO:K02372] [EC:4.2.1.59] ... The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin ...
... acyl-carrier-protein) synthase 2 [KO:K09458] [EC:2.3.1.179] ... beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [KO: ... The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin ... Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex. ... Biotin is covalently attached to biotin-dependent carboxylase by biotin protein ligase, also known as holocarboxylase synthase ...
Acyl-Carrier-Protein) Synthase. Not Available. 1. 1. Details. 4-Hydroxycoumarins. Substances found in many plants, containing ... Enzymes that transfer the ADP-RIBOSE group of NAD or NADP to proteins or other small mo... more. 1. 3. Details. ... Enzymes from the transferase class that catalyze the transfer of acyl groups from donor... more. 1. 0. Details. ... 3-Hydroxysteroid Dehydrogenases, antagonists & inhibitors. Not Available. 1. 4. Details. 3-Oxoacyl-( ...
Homologous to beta-keto-acyl-acyl-carrier protein synthase. PA0998. pqsC. 4.5. 0.0031. Homologous to beta-keto-acyl-acyl- ... Membrane protein component of ABC phosphate transporter. PA5368. pstC. 27.7. 3.9E−09. Membrane protein component of ABC ... Binding protein component of ABC phosphonate transporter. PA3384. phnC. 27.2. 2.5E−07. ATP-binding component of ABC phosphonate ... Probable chemotaxis protein methyltransferase. PA0176. aer2. 15.4. 0.0001. Aerotaxis transducer methyl-accepting chemotaxis ...
... acyl carrier protein) synthase; 4, acetyl-CoA acetyltransferase; 5, 3-hydroxyacyl-CoA dehydrogenase; 6, enoyl-CoA hydratase; 7 ... enoyl-(acyl carrier protein) reductase (NADH); 8, acetate CoA-transferase; 9, butyrate kinase; 10, citrate synthase; 11, ... protein plus protein, 16S plus 16S, metabolomics plus metabolomics, 16S plus protein, protein plus metabolomics, and 16S plus ... of protein were normalized as described below (42): Normalized. SC. i. =. ∑. j. =. 1. M. ∑. k. =. 1. N. SC. k. M. ∑. k. =. 1. N ...
... and ASTRAL compendium for protein structure and sequence analysis ... acyl-carrier-protein] synthase 3. Species: Escherichia coli [ ... acyl-carrier-protein] synthase 3. Species: Escherichia coli [TaxId:562]. Gene: fabH. Database cross-references and differences ... Description: Methanethiol-Cys 112 Inhibition Complex of E. Coli Ketoacyl Synthase III (FabH) and Coenzyme A. Class: transferase ... SCOPe: Structural Classification of Proteins - extended. Release 2.05 (updated 2016-01-14, stable release February 2015) ...
... and ASTRAL compendium for protein structure and sequence analysis ... acyl-carrier-protein] synthase III. Species: Escherichia coli [ ... Description: CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III WITH BOUND dichlorobenzyloxy-indole-carboxylic acid inhibitor ... SCOPe: Structural Classification of Proteins - extended. Release 2.06 (updated 2017-12-21, stable release February 2016) ...
... acyl-carrier-protein synthase activity]. • acyl-[acyl-carrier-protein hydrolase activity]. • hydrolase activity. • palmitoyl-[ ... fatty acid synthase activity. • myristoyl-[acyl-carrier-protein hydrolase activity]. • enoyl-[acyl-carrier-protein reductase ( ... acyl-carrier-protein dehydratase activity]. • protein homodimerization activity. • catalytic activity. • [acyl-carrier-protein ... identical protein binding. • oleoyl-[acyl-carrier-protein hydrolase activity]. • oxidoreductase activity. • 3-oxoacyl-[ ...
... acyl-carrier-protein] synthase i Enzyme Information. 2.3.1.179. Beta-ketoacyl-[acyl-carrier-protein] synthase II. ... Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier- protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein ... acyl-carrier-protein].. -!- Involved in the dissociated (or type II) fatty acid biosynthesis system that occurs in plants and ... CATH: Protein Structure Classification Database by I. Sillitoe, N. Dawson, T. Lewis, D. Lee, J. Lees, C. Orengo is licensed ...
... acyl-carrier-protein] synthase II of Streptococcus equi ssp. zooepidemicus which confers protective effects Li Yi , Weiping ... acyl-carrier-protein] synthase II of Streptococcus equi ssp. zooepidemicus which confers protective effects Li Yi , Weiping ... Identification of a novel protective antigen, 3-oxoacyl-[ ... Identification of a novel protective antigen, 3-oxoacyl-[ ...
... acyl-carrier-protein]reductase, fatty acid/phosphlipid synthesis protein, fatty acid-CoA ligase, and acetyl/propionyl-CoA ... probable acyl-CoA dehydrogenase, probable multi-domain beta keto-acyl synthase, and acetyl/propionyl-CoA carboxylase involved ... Enoyl-[acyl-carrier-protein] reductase (FabI). 4. 27 (23). P54616. Bacillus subtilis. Fatty acid biosynthesis. ... SsrA-binding protein. 4. 41 (25). Q83N13. Tropheryma whipplei. Protein biosynthesis. Foldase protein. 2. 24 (21). P24327. ...
... acyl-CoA synthetases (family 6), acyl-CoA dehydrogenases (family 8), enoyl-CoA hydratase/isomerase family proteins (family 11 ... 4B ). This cluster includes genes coding for two polyketide synthases (NbtB and -C), three nonribosomal peptide synthetases ( ... Antigen 85 family proteins of M. tuberculosis are known as fibronectin-binding proteins (19). M. tuberculosis has four proteins ... Comparison with other bacterial RpoB proteins suggested that the nocardial RpoB protein is sensitive to rifampin. In contrast, ...
... acyl-carrier-protein) synthase III. 1 (up). 58 (55). gi/83952158. Fatty acid biosynthesis. ... acyl-carrier-protein]reductase (FabI) and fatty acid-CoA ligase [11]. In our study, FabI and β-ketoacyl carrier protein ... 280 proteins were totally identified and 188 proteins were separated as acetate-related proteins in BL-4. Acetate was converted ... BL-4 proteins (15 μg). Arrows indicate different patterns of proteins on the gel. 1, molecular size marker; 2, acetate-fed ...
  • The chromosome of N. farcinica , unlike that of Streptomyces ( 13 , 14 ), has a circular topology ( Fig. 1 ) and encodes 53 tRNA genes, three copies of ribosomal RNA operons, and 5,674 predicted protein-coding sequences. (pnas.org)
  • After 3 days of treatment, analysis revealed that 3,410 genes were differentially expressed in response to at least one of the compounds. (frontiersin.org)
  • FabR represses expression of the two genes, fabA and fabB, required for unsaturated fatty acid synthesis and has been reported to require the presence of an unsaturated thioester (of either acyl carrier protein or CoA) in order to bind the fabA and fabB promoters in vitro. (nih.gov)
  • We have further analyzed these 446 genes by the protein sequence database to list some 96 genes whose products are possibly exposed on the pathogen surface. (oaji.net)
  • 0.05), which were similar to their protein expression levels, suggesting that they might be T. spiralis molting-related genes. (biomedcentral.com)
  • Sequence of a 28.6 kb region of yeast chromosome XI includes the FBA1 and TOA2 genes, an open reading frame (ORF) similar to a translationally controlled tumour protein, one ORF containing motifs also found in plant storage proteins and 13 ORFs with weak or no homology to known proteins. (ymdb.ca)
  • The product of four genes shows high identity to proteins involved in the biosynthesis of menaquinone via futalosine. (biomedcentral.com)
  • Johnson DR, Knoll LJ, Levin DE, Gordon JI: Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolism. (smpdb.ca)
  • Johnson DR, Knoll LJ, Rowley N, Gordon JI: Genetic analysis of the role of Saccharomyces cerevisiae acyl-CoA synthetase genes in regulating protein N-myristoylation. (smpdb.ca)
  • We report that FabR bound the intact promoter regions of both fabA and fabB in the absence of unsaturated acyl thioesters, but bound the two promoters differently. (nih.gov)
  • However, in contrast to E. coli, gel mobility shift assays indicated that neither E. coli nor V. cholerae FabRs bound the V. cholerae fabB promoter, although both proteins efficiently bound the V. cholerae fabA promoter. (nih.gov)
  • Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common . (jcvi.org)
  • In this study, Ralstonia eutropha was used to elucidate the protein regulations when the bacterial cells pre-cultivated on glucose were exposed to three representative short chain organic acids, acetic, propionic and levulinic acids. (ijbs.com)
  • The most extensively studied class of bacterial QS molecules are N -acyl homoserine lactones (AHLs). (frontiersin.org)
  • Bacterial cells were disrupted in a lysis buffer containing 30 mM Tris, 2 M thiourea, 7 M urea, 4% CHAPS, 2% IPG buffer pH 3-10 and protease inhibitors and then subjected to sonication in order to solubilize as much as possible the bacterial proteins. (bvsalud.org)
  • Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. (uniprot.org)
  • This analysis of the sequence supports the view that the erythromycin-producing polyketide synthase contains three multienzyme polypeptides, each of which accomplishes two successive cycles of polyketide chain extension. (nih.gov)
  • 3. The i and j are positions as given in the consensus sequence. (bakerlab.org)
  • We describe several protein sequence statistics designed to evaluate distinctive attributes of residue content and arrangement in primary structure. (oaji.net)
  • The computer program SEQUANA (statistical analysis of protein sequences) calculates all the statistics for any individual protein sequence input and is available for the WINDOWS environment through electronic mail on request to [email protected] (oaji.net)
  • Furthermore, we showed CaCO 3 that precipitates earlier in an experiment modifies membrane rigidity of YS11 strain via upregulation of branched chain fatty acid synthesis. (springer.com)
  • Thus, virulence-related protein secretion is localized in mycobacteria, suggesting new potential therapeutic targets, which are urgently needed. (nih.gov)
  • Despite the identification of several key adherence factors, including pneumococcal surface adhesin A (PsaA), pneumococcal serine repeat protein (PsrP), choline binding proteins (CbpA, CbpE), pilus protein (RrgA), plasminogen- and fibronectin-binding proteins (PfbA and PfbB), pneumococcal adherence and virulence factor A and B (PavA and PavB) [ 8 - 15 ], our understanding of the molecular mechanisms of pneumococcal adherence and invasion remains incomplete. (cdc.gov)
  • Bagnat M, Simons K: Lipid rafts in protein sorting and cell polarity in budding yeast Saccharomyces cerevisiae. (smpdb.ca)
  • Citrate (si)-Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
  • A collection of articles that focus on an array of different scientific topics such as pathways, cancer, transmembrane proteins. (cusabio.com)
  • The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. (mybiosource.com)
  • To fully address the effect of the genetically-recessive single mutation of W60G on regulatory function of FadR protein, we employed the in vitro and in vivo approaches including EMSA and transcriptional fusion. (nih.gov)
  • p>When browsing through different UniProt proteins, you can use the 'basket' to save them, so that you can back to find or analyse them later. (uniprot.org)
  • Insulin, glucose and AICAR (an activator of AMP-activated protein kinase) affected changes in hypothalamic FAS mRNA, which may be regulated via the SREBP1c dependent or independent pathway. (pku.edu.cn)
  • No cofactors are required as 1- O- trans- cinnamoyl-β- D -glucopyranose itself is an "energy-rich" (activated) acyl-donor, comparable to CoA-thioesters. (qmul.ac.uk)
  • C) The wild-type FadR protein (FadRWT) can bind to promoter regions covering the FadR-binding sites of fadBA and fadM, whereas FadRk113 does not. (nih.gov)
  • As we expected, the wild-type FadR protein (FadRWT) exhibited obvious binding to fadL (fadD) promoter (Fig. 3A and 3B), however the FadRK113 protein was not visualized to interact with them at the same protein level used in our trials (no more than 10 pmol). (nih.gov)
  • 2002. Fenton reaction is primarily involved in a mechanism of (-)-epigallocatechin-3-gallate to induce osteoclastic cell death. (scbt.com)
  • 1. Mock, H.-P., Strack, D. Energetics of uridine 5'-diphosphoglucose-hydroxy-cinnamic acid acyl-glucotransferase reaction. (qmul.ac.uk)