3-Hydroxyanthranilate 3,4-Dioxygenase: An enzyme that catalyzes the conversion of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. It was formerly characterized as EC 1.13.1.6.3-Hydroxyanthranilic Acid: An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.KynurenineDioxygenases: Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS; GIBBERELLINS; and HYOSCYAMINE; and for degradation of AROMATIC HYDROCARBONS.ortho-Aminobenzoates: Benzoic acids, salts, or esters that contain an amino group attached to carbon number 2 or 6 of the benzene ring structure.Oxygenases: Oxidases that specifically introduce DIOXYGEN-derived oxygen atoms into a variety of organic molecules.Kynurenine 3-Monooxygenase: An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5.Nitrobenzoates: Benzoic acid or benzoic acid esters substituted with one or more nitro groups.Tryptophan: An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.4-Hydroxyphenylpyruvate Dioxygenase: An enzyme that catalyzes the conversion of 4-hydroxyphenylpyruvate plus oxygen to homogentisic acid and carbon dioxide. EC 1.13.11.27.Catechol 2,3-Dioxygenase: Catalyzes the oxidation of catechol to 2-hydroxymuconate semialdehyde in the carbazole and BENZOATE degradation via HYDROXYLATION pathways. It also catalyzes the conversion of 3-methylcatechol to cis, cis-2-hydroxy-6-oxohept-2,4-dienoate in the TOLUENE and XYLENE degradation pathway. This enzyme was formerly characterized as EC 1.13.1.2.Carboxy-Lyases: Enzymes that catalyze the addition of a carboxyl group to a compound (carboxylases) or the removal of a carboxyl group from a compound (decarboxylases). EC 4.1.1.Protocatechuate-3,4-Dioxygenase: An enzyme that catalyzes the oxidation of protocatechuate to 3-carboxy-cis-cis-muconate in the presence of molecular oxygen. It contains ferric ion. EC 1.13.11.3.Cysteine Dioxygenase: An enzyme that catalyzes the conversion of L-CYSTEINE to 3-sulfinoalanine (3-sulfino-L-alanine) in the CYSTEINE metabolism and TAURINE and hypotaurine metabolic pathways.Catechol 1,2-Dioxygenase: An enzyme that catalyzes the oxidation of catechol to muconic acid with the use of Fe3+ as a cofactor. This enzyme was formerly characterized as EC 1.13.1.1 and EC 1.99.2.2.Tryptophan Oxygenase: A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.Homogentisate 1,2-Dioxygenase: A mononuclear Fe(II)-dependent oxygenase, this enzyme catalyzes the conversion of homogentisate to 4-maleylacetoacetate, the third step in the pathway for the catabolism of TYROSINE. Deficiency in the enzyme causes ALKAPTONURIA, an autosomal recessive disorder, characterized by homogentisic aciduria, OCHRONOSIS and ARTHRITIS. This enzyme was formerly characterized as EC 1.13.1.5 and EC 1.99.2.5.Catechols: A group of 1,2-benzenediols that contain the general formula R-C6H5O2.Pseudomonas: A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.Biodegradation, Environmental: Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.
*  3-hydroxyanthranilate 3,4-dioxygenase
In enzymology, a 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) is an enzyme that catalyzes the chemical reaction 3- ... hydroxyanthranilate + O2 ⇌ {\displaystyle \rightleftharpoons } 2-amino-3-carboxymuconate semialdehyde Thus, the two substrates ... DECKER RH, KANG HH, LEACH FR, HENDERSON LM (1961). "Purification and properties of 3-hydroxyanthranilic acid oxidase". J. Biol ... The systematic name of this enzyme class is 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing). Other names in ...
*  List of MeSH codes (D08)
... dioxygenases MeSH D08.811.682.690.416.277 --- catechol 1,2-dioxygenase MeSH D08.811.682.690.416.305 --- catechol 2,3- ... 2-oxoglutarate 5-dioxygenase MeSH D08.811.682.690.708.673 --- procollagen-proline dioxygenase MeSH D08.811.682.690.708.715 --- ... cysteine dioxygenase MeSH D08.811.682.690.416.326 --- homogentisate 1,2-dioxygenase MeSH D08.811.682.690.416.328 --- 3- ... hydroxyanthranilate 3,4-dioxygenase MeSH D08.811.682.690.416.330 --- 4-hydroxyphenylpyruvate dioxygenase MeSH D08.811.682.690. ...
*  List of EC numbers (EC 1)
... sulfur dioxygenase EC 1.13.11.19: cysteamine dioxygenase EC 1.13.11.20: cysteine dioxygenase EC 1.13.11.21: now *EC 1.14.99.36 ... gibberellin 3b-dioxygenase EC 1.14.11.16: peptide-aspartate b-dioxygenase EC 1.14.11.17: taurine dioxygenase EC 1.14.11.18: ... 2-dioxygenase EC 1.14.12.11: toluene dioxygenase EC 1.14.12.12: naphthalene 1,2-dioxygenase EC 1.14.12.13: 2-chlorobenzoate 1,2 ... 2-dioxygenase EC 1.14.12.16: 2-hydroxyquinoline 5,6-dioxygenase EC 1.14.12.17: nitric oxide dioxygenase EC 1.14.12.18: biphenyl ...
岩木 宏明 - 化学生命工学部 生命・生物工学  岩木 宏明 - 化学生命工学部 生命・生物工学
2-dioxygenase.学術研究助成基金 200504-200603 ... KU-46株の2,4-ジニトロフェノール分解系遺伝子群の取得査読無その他共著高田健吾 (D);岩木宏明;長谷川喜衛;日本農芸化 ... KU-46株による2,4-ジニトロフェノールの分解査読無その他共
more infohttp://gakujo.kansai-u.ac.jp/profile/ja/f7c4d4dRdc88edf6Q06qH93_15.html
3-hydroxyanthranilate 3,4-dioxygenase - Wikipedia  3-hydroxyanthranilate 3,4-dioxygenase - Wikipedia
In enzymology, a 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) is an enzyme that catalyzes the chemical reaction 3- ... hydroxyanthranilate + O2 ⇌ {\displaystyle \rightleftharpoons } 2-amino-3-carboxymuconate semialdehyde Thus, the two substrates ... DECKER RH, KANG HH, LEACH FR, HENDERSON LM (1961). "Purification and properties of 3-hydroxyanthranilic acid oxidase". J. Biol ... The systematic name of this enzyme class is 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing). Other names in ...
more infohttps://en.wikipedia.org/wiki/3-hydroxyanthranilate_3,4-dioxygenase
haao - 3-hydroxyanthranilate 3,4-dioxygenase - Xenopus laevis (African clawed frog) - haao gene & protein  haao - 3-hydroxyanthranilate 3,4-dioxygenase - Xenopus laevis (African clawed frog) - haao gene & protein
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously ... 3-HAOUniRule annotation. ,p>Manual validated information which has been generated by the UniProtKB automatic annotation system ... Annotation score:3 out of 5. ,p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB ... 3-hydroxyanthranilate 3,4-dioxygenaseUniRule annotation. ,p>Manual validated information which has been generated by the ...
more infohttp://www.uniprot.org/uniprot/Q6P7I0
Recombinant Human 3-hydroxyanthranilate 3,4-dioxygenase, His-tagged HAAO-2403H - Creative BioMart  Recombinant Human 3-hydroxyanthranilate 3,4-dioxygenase, His-tagged HAAO-2403H - Creative BioMart
3hydroxyanthranilic acid dioxygenase; 3-HAO; 3-hydroxyanthranilate 3;3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid ... Recombinant Human 3-hydroxyanthranilate 3,4-dioxygenase, His-tagged. Download Datasheet See All HAAO Products. Bring this ... Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°Cor -70°C. Avoid repeated freezing ... dioxygenase;3HAO_HUMAN; 4-dioxygenase; haao; HAD; HAO; HAD; 3-hydroxyanthranilateoxygenase; 3-hydroxyanthranilic acid ...
more infohttps://www.creativebiomart.net/description_107313_8.htm
BNA1 - 3-hydroxyanthranilate 3,4-dioxygenase - Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage...  BNA1 - 3-hydroxyanthranilate 3,4-dioxygenase - Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage...
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously ... 3-HAOUniRule annotation. ,p>Manual validated information which has been generated by the UniProtKB automatic annotation system ... Annotation score:3 out of 5. ,p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB ... 3-hydroxyanthranilate 3,4-dioxygenase (BNA1). This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part ...
more infohttp://www.uniprot.org/uniprot/B2AAJ5
Nickel in the structure of The Crystal Structure of 3-Hydroxyanthranilate 3,4- Dioxygenase From Saccharomyces Cerevisiae (pdb...  Nickel in the structure of The Crystal Structure of 3-Hydroxyanthranilate 3,4- Dioxygenase From Saccharomyces Cerevisiae (pdb...
The Crystal Structure of 3-Hydroxyanthranilate 3,4- Dioxygenase From Saccharomyces Cerevisiae ... Dioxygenase From Saccharomyces Cerevisiae (pdb code 1zvf). This binding sites where shown with 5.0 Angstroms radius around ... Nickel binding site 3 out of 4 in 1zvf. Click to enlarge. Click to enlarge. Mono- and Stereo- picture of 5.0 Angstrom ... Nickel binding site 4 out of 4 in 1zvf. Click to enlarge. Click to enlarge. Mono- and Stereo- picture of 5.0 Angstrom ...
more infohttp://nickel.atomistry.com/pdb1zvf.html
Iron in the structure of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed With...  Iron in the structure of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed With...
Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed With 3-Hydroxyanthranilic ... The binding sites of Iron atom in the structure of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia ... Iron in the structure of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed With ... Metallidurans Complexed With 3-Hydroxyanthranilic Acid (pdb code 1yfy). This binding sites where shown with 5.0 Angstroms ...
more infohttp://iron.atomistry.com/pdb1yfy.html
SCOPe 2.07: Structural Classification of Proteins - extended  SCOPe 2.07: Structural Classification of Proteins - extended
Keywords: Complex structure, Dioxygenase, Mutant I142P, OXIDOREDUCTASE, 4-Cl-3-HAA. Deposited on 2018-04-19, released 2018-06- ... Compound: 3-hydroxyanthranilate 3,4-dioxygenase. Species: Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 ... Description: Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142P from Cupriavidus metallidurans in complex with 4- ...
more infohttp://scop.berkeley.edu/pdb/code=6d61
EC 1.13.11  EC 1.13.11
... 18 sulfur dioxygenase. EC 1.13.11.19 cysteamine dioxygenase. EC 1.13.11.20 cysteine dioxygenase. EC 1.13.11.21 now ... 5-dioxygenase. EC 1.13.11.9 2,5-dihydroxypyridine 5,6-dioxygenase. EC 1.13.11.10 7,8-dihydroxykynurenate 8,8a-dioxygenase. EC ... Other name(s): 10R-DOX; (10R)-dioxygenase; 10R-dioxygenase. Systematic name: linoleate:oxygen (10R)-oxidoreductase. Comments: ... EC 1.13.11.87 endo-cleaving rubber dioxygenase. EC 1.13.11.1. Accepted name: catechol 1,2-dioxygenase. Reaction: catechol + O2 ...
more infohttps://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC1/1311.html
HATADA METHYLATED IN LUNG CANCER UP  HATADA METHYLATED IN LUNG CANCER UP
DNA methylation in the promoter region of a gene is associated with a loss of that gene's expression and plays an important role in gene silencing. The inactivation of tumor-suppressor genes by aberrant methylation in the promoter region is well recognized in carcinogenesis. However, there has been little study in this area when it comes to genome-wide profiling of the promoter methylation. Here, we developed a genome-wide profiling method called Microarray-based Integrated Analysis of Methylation by Isoschizomers to analyse the DNA methylation of promoter regions of 8091 human genes. With this method, resistance to both the methylation-sensitive restriction enzyme HpaII and the methylation-insensitive isoschizomer MspI was compared between samples by using a microarray with promoter regions of the 8091 genes. The reliability of the difference in HpaII resistance was judged using the difference in MspI resistance. We demonstrated the utility of this method by finding epigenetic mutations in ...
more infohttp://software.broadinstitute.org/gsea/msigdb/cards/HATADA_METHYLATED_IN_LUNG_CANCER_UP.html
Genome-wide association study of reproductive traits in Nellore heifers using Bayesian inference | Springer for Research &...  Genome-wide association study of reproductive traits in Nellore heifers using Bayesian inference | Springer for Research &...
Table 4 Significant SNPs for age at first calving with chromosome number, percentage of phenotypic variance explained by the ... 4.. Shiotsuki L, Silva 2nd JAV, Tonhati H, Albuquerque LG. Genetic associations of sexual precocity with growth traits and ... 3.. Formigoni IB, Ferraz JBS, Silva JAIIV, Eler JP, Brumatti RC. Valores econômicos para habilidade de permanência e ... Table 3 Significant SNPs for heifer rebreeding with chromosome number, percentage of phenotypic variance explained by the SNP ...
more infohttps://rd.springer.com/article/10.1186/s12711-015-0146-0
HAAO - PCR Primer Pair - SYBR | PrimePCR | Bio-Rad  HAAO - PCR Primer Pair - SYBR | PrimePCR | Bio-Rad
3-Hydroxyanthranilate 34-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases ... HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is ...
more infohttp://www.bio-rad.com/en-us/prime-pcr-assays/assay/qhsacid0007210-primepcr-sybr-green-assay-haao-human
IMP: Integrative Multi-species Prediction  IMP: Integrative Multi-species Prediction
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide). 0.010 ... aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase). 0.014. ... leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like. 0.062. ... hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1. 0.027. ...
more infohttp://imp.princeton.edu/predictions/process/rat-context-global/9030/?gene=101432
Promoter hypermethylation of CIDEA, HAAO and RXFP3 associated with microsatellite instability in endometrial carcinomas  Promoter hypermethylation of CIDEA, HAAO and RXFP3 associated with microsatellite instability in endometrial carcinomas
3. Jones PA, Baylin SB. The epigenomics of cancer. Cell. 2007;128:683-92. [PMC free article] [PubMed] ... 4. Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet. 2007;8:286-98. [PubMed] ... 4. Methylation of HAAO CpG island and clinicopathologic covariates analyses in primary endometrial carcinomas. (A) Methylation ... 2). The detailed methylation level of each CpG unit (1-4 CpG sites per unit) was showed in Supplementary Fig. S1. These results ...
more infohttp://pubmedcentralcanada.ca/pmcc/articles/PMC2849881/?lang=en-ca
MODULE 181  MODULE 181
Copyright (c) 2004-2017 Broad Institute, Inc., Massachusetts Institute of Technology, and Regents of the University of California. All rights reserved ...
more infohttp://software.broadinstitute.org/gsea/msigdb/cards/MODULE_181.html
Shop by Manufacturer RAYBIOTECH | Lucerna-Chem AG  Shop by Manufacturer RAYBIOTECH | Lucerna-Chem AG
4-1BBL, Human recombinant Supplier: RayBiotech • Format: Lyophilized from 5 mM Tris,pH 8.0 + 75 mM NaCl. ... 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1, Human Recombinant Supplier: RayBiotech • Format: Sterile Filtered clear solution. ... 3-Ketodihydrosphingosine Reductase, Human Recombinant Supplier: RayBiotech • Format: The ,KDSR is supplied as a sterile ... 4-1BB Ligand, Human Recombinant Supplier: RayBiotech • Format: Sterile Filtered White lyophilized (freeze-dried) powder. ...
more infohttps://lucerna-chem.ch/shop/supplier/45/raybiotech
IMP: Integrative Multi-species Prediction  IMP: Integrative Multi-species Prediction
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group). 0.016. ... hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit. 0.023. ... membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific). 0.011. ...
more infohttp://imp.princeton.edu/predictions/process/human-context-global/3427/?gene=9991
EFNCRP00000009038 protein (Neurospora crassa) - STRING interaction network  EFNCRP00000009038 protein (Neurospora crassa) - STRING interaction network
... hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (180 aa) ... hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate ... hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate ... hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate ...
more infohttps://string-db.org/network/5141.EFNCRP00000009038
EC 1.13.11  EC 1.13.11
... 18 sulfur dioxygenase. EC 1.13.11.19 cysteamine dioxygenase. EC 1.13.11.20 cysteine dioxygenase. EC 1.13.11.21 now ... 5-dioxygenase. EC 1.13.11.9 2,5-dihydroxypyridine 5,6-dioxygenase. EC 1.13.11.10 7,8-dihydroxykynurenate 8,8a-dioxygenase. EC ... Other name(s): 10R-DOX; (10R)-dioxygenase; 10R-dioxygenase. Systematic name: linoleate:oxygen (10R)-oxidoreductase. Comments: ... EC 1.13.11.82 8'-apo-carotenoid 13,14-cleaving dioxygenase. EC 1.13.11.1. Accepted name: catechol 1,2-dioxygenase. Reaction: ...
more infohttp://www.sbcs.qmul.ac.uk/iubmb/enzyme/EC1/1311.html
Human Metabolome Database: Showing metabocard for 2-Amino-3-carboxymuconic acid semialdehyde (HMDB0001330)  Human Metabolome Database: Showing metabocard for 2-Amino-3-carboxymuconic acid semialdehyde (HMDB0001330)
2. 3-hydroxyanthranilate 3,4-dioxygenase. General function:. Involved in 3-hydroxyanthranilate 3,4-dioxygenase activity. ... 2-Amino-3-carboxymuconic acid semialdehyde. Description. 2-amino-3-carboxymuconic acid semialdehyde is an intermediate ... I. ENZYMIC FORMATION OF GLUTARIC ACID FROM 3-HYDROXYANTHRANILIC ACID. J Biol Chem. 1965 Feb;240:733-9. [PubMed:14275129 ] ... 2-Amino-3-carboxymuconic semialdehyde is enzymatically converted to 2-aminomuconate via 2-aminomuconic semialdehyde. (PMID: ...
more infohttp://www.hmdb.ca/metabolites/HMDB0001330
  • Although tumor suppressor genes can be inactivated by deletions and/or mutations in cancer cells, epigenetic mechanisms including aberrant methylation of CpG sites within the promoter region also contribute to gene silencing [ 3 , 4 ]. (pubmedcentralcanada.ca)
  • McpP has a CACHE-type LBD, and we present data indicating that CACHE-containing chemoreceptors of other species also mediate taxis to C 2 and C 3 carboxylic acids. (asm.org)
  • Brain tissue QUIN levels at 4 days postischemia exceeded blood concentrations, minimizing a role for breakdown of the blood-brain barrier. (fujita-hu.ac.jp)
  • Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Nickel in the PDB 1zvf. (atomistry.com)
  • Cluster I domains include the 4-helix bundle, GAF, PAS, CHASE, and CACHE domains ( 12 - 16 ). (asm.org)