An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.
An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
Sympathomimetic, vasoconstrictor agent.
Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.
Analogs or derivatives of AMPHETAMINE. Many are sympathomimetics and central nervous system stimulators causing excitation, vasopressin, bronchodilation, and to varying degrees, anorexia, analepsis, nasal decongestion, and some smooth muscle relaxation.
Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection.
A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.
Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.
The application of TOXICOLOGY knowledge to questions of law.
Drugs obtained and often manufactured illegally for the subjective effects they are said to produce. They are often distributed in urban areas, but are also available in suburban and rural areas, and tend to be grossly impure and may cause unexpected toxicity.
A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A general class of ortho-dihydroxyphenylalkylamines derived from tyrosine.
Experiments designed to determine the potential toxic effects of one-time, short-term exposure to a chemical or chemicals.
The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
A plant genus of the family RANUNCULACEAE. Members contain BERBERINE and other isoquinoline ALKALOIDS.
A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
Disorders related or resulting from use of amphetamines.
The period of history from 1601 of the common era to the present.
Inorganic and organic derivatives of sulfuric acid (H2SO4). The salts and esters of sulfuric acid are known as SULFATES and SULFURIC ACID ESTERS respectively.
Dissertations embodying results of original research and especially substantiating a specific view, e.g., substantial papers written by candidates for an academic degree under the individual direction of a professor or papers written by undergraduates desirous of achieving honors or distinction.
An infraorder of chiefly marine, largely carnivorous CRUSTACEA, in the order DECAPODA, including the genera Cancer, Uca, and Callinectes.
A cabinet department in the Executive Branch of the United States Government concerned with improving and maintaining farm income and developing and expanding markets for agricultural products. Through inspection and grading services it safeguards and insures standards of quality in food supply and production.
The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.
Control of drug and narcotic use by international agreement, or by institutional systems for handling prescribed drugs. This includes regulations concerned with the manufacturing, dispensing, approval (DRUG APPROVAL), and marketing of drugs.
A phenethylamine that is an isomer of EPHEDRINE which has less central nervous system effects and usage is mainly for respiratory tract decongestion.
Laws concerned with manufacturing, dispensing, and marketing of drugs.
The act or practice of literary composition, the occupation of writer, or producing or engaging in literary work as a profession.
Disturbances in the body's WATER-ELECTROLYTE BALANCE.
Educational institutions providing facilities for teaching and research and authorized to grant academic degrees.
An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.
Health services for college and university students usually provided by the educational institution.
Persons whose profession is to give legal advice and assistance to clients and represent them in legal matters. (American Heritage Dictionary, 3d ed)
A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It produces strychnine-like convulsions rather than narcosis. It may be habit-forming and is a controlled substance (opiate) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.12 (1985). (From Merck Index, 11th ed)
Persons who are enrolled in research studies or who are otherwise the subjects of research.
A synthetic hormone used for androgen replacement therapy and as an hormonal antineoplastic agent (ANTINEOPLASTIC AGENTS, HORMONAL).
A cabinet department in the Executive Branch of the United States Government concerned with administering those agencies and offices having programs pertaining to domestic national security.
Freedom of equipment from actual or potential hazards.
3 (1-2): 28. Retrieved 9 October 2013.. *^ Lancashire, Robert J. (13 October 2011). "Unit 9: Crime - Reagent Kits". University ... 2,5-Dimethoxy-4-bromoamphetamine (DOB). Olive Green - Yellow 2-FMA. Rapidly fizzes and dissolves. Colourless/Light yellow[ ... Final colors produced by Marquis Reagent with various substances[1]:3-6[8] Substance Color ... 3] in his magister dissertation in 1896;[4] and named after him,[5] and was tested for the first time at the University of ...
5-methylenedioxyamphetamine; 5-methoxy-MDA) is a psychedelic and entactogen drug of the amphetamine class. It is an analogue of ... 38 (3): 505-12. doi:10.1016/0091-3057(91)90005-M. PMID 1829838. S2CID 2740262. Zhang Z, An L, Hu W, Xiang Y (April 2007). "3D- ... 21 (4): 145-53. doi:10.1007/s10822-006-9090-y. PMID 17203365. S2CID 25343432. "Archived copy" (PDF). Archived from the original ... 3,4-Methylenedioxyamphetamine (MDA) Lophophine Trimethoxyamphetamine (TMA) McKenna DJ, Guan XM, Shulgin AT (March 1991). "3,4- ...
5-methylenedioxyamphetamine". PiHKAL • info. 10 November 2009. Retrieved 20 November 2011. Shulgin, A. T.; Sargent, T. (1967 ...
Methylenedioxy)amphetamine analogues alkylated on the dioxole ring". Journal of Medicinal Chemistry. 22 (10): 1264-7. doi: ... methylenedioxy)amphetamine (MDA) and its derivatives". Chemistry & Biodiversity. 3 (3): 326-36. CiteSeerX 10.1.1.688.5803. doi: ... 34 (3): 571-6. doi:10.1016/0091-3057(89)90560-1. PMID 2623014. Capela JP, Carmo H, Remião F, Bastos ML, Meisel A, Carvalho F ( ... 39 (3): 210-71. CiteSeerX 10.1.1.670.6897. doi:10.1007/s12035-009-8064-1. PMID 19373443. Sarkar S, Schmued L (August 2010). " ...
5-dimethoxy-4-methylamphetamine a.k.a. DOM), entactogens (e.g., 3,4-methylenedioxyamphetamine a.k.a. MDA), appetite ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 33 (2): 703-10. doi:10.1021/jm00164a037. PMID 1967651.. .mw- ... 28 (4): 345-55. doi:10.1002/hup.2298. PMID 23881883.. *^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug ... 9 (3-4): 299-312. PMID 8400010.. *^ Sprague JE, Johnson MP, Schmidt CJ, Nichols DE (October 1996). "Studies on the mechanism of ... 18 (4): 305-13. doi:10.1080/02791072.1986.10472362. PMID 2880944.. *^ Oberlender R, Nichols DE (December 1990). "(+)-N-methyl-1
ALPHA (alpha-ethyl-3,4-methylenedioxybenzylamine) is a lesser-known psychedelic drug and a substituted benzylamine. It is also ... It lasts about 3 hours. Very little data exists about the pharmacological properties, metabolism, and toxicity of ALPHA. ... 4-methylenedioxyamphetamine (MDA). ALPHA was first synthesized by Alexander Shulgin. In his book PIHKAL on the MDA page, the ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 33 (2): 703-10. doi:10.1021/jm00164a037. PMID 1967651.. ... Indane or indan is an organic compound with the formula C6H4(CH2)3. It is a colorless liquid hydrocarbon. It is a petrochemical ... Indene 1,3-indandione Hawley, Gessner G. (1977). The Condensed Chemical Dictionary. Van Nostrand Reinhold Company. p. 464. ISBN ... 4-methylindane and 5-methylindane (where one methyl group is attached to the benzene ring), and various dimethylindanes. Other ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 33 (2): 703-10. doi:10.1021/jm00164a037. PMID 1967651.. ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 33 (2): 703-10. doi:10.1021/jm00164a037. PMID 1967651. v t e ... Nichols DE, Brewster WK, Johnson MP, Oberlender R, Riggs RM (February 1990). "Nonneurotoxic tetralin and indan analogues of 3,4 ...
5-methylenedioxyamphetamine. 3 Trimethoxyamphetamine (TMA). X,X,X-Trimethoxyamphetamine. 3 ... 4-dimethoxyamphetamine) -CH3. -O-CH3. -O-CH3. 3,4,5-TMA (3,4,5-trimethoxyamphetamine, α-methylmescaline) -CH3. -O-CH3. -O-CH3. ... MDEA (3,4-methylenedioxy-N-ethylamphetamine) -CH2-CH3. -CH3. -O-CH2-O- ... EDMA (3,4-ethylenedioxy-N-methylamphetamine) -CH3. -CH3. -O-CH2-CH2-O- ...
... (MDAL or 3,4-methylenedioxy-N-allylamphetamine) is a lesser-known psychedelic drug. It is also ... 4-methylenedioxyamphetamine (MDA). MDAL was first synthesized by Alexander Shulgin. In his book PiHKAL, the minimum dosage is ...
1984;9(4):280-5. "Emedicine". "Likarstwo.ru". Dixon AK, Hill RC, Roemer D, Scholtysik G. Pharmacological properties of 4-(1- ... 1977 Oct;56(4):276-9. Banki CM. Clinical observations with pizotifene (Sandomigran) in the treatment of nonmigrainous depressed ... 2007 Aug 6;187(3):142-6. Barnes N, Millman G. Do pizotifen or propranolol reduce the frequency of migraine headache? Archives ... Pizotyline effectively attenuates the stimulus effects of N-methyl-3,4-methylenedioxyamphetamine (MDMA). Pharmacology ...
3,4-Methylenedioxy-N,N-dimethylamphetamine (MDDM) is a lesser-known psychedelic drug. It is also the N,N-dimethyl analog of 3,4 ... methylenedioxyamphetamine (MDA). MDDM was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have ... This compound is however occasionally encountered as an impurity in 3,4-methylenedioxy-N-methylamphetamine (MDMA) which has ...
ISBN 978-3-03788-700-4. Świst M, Wilamowski J, Zuba D, Kochana J, Parczewski A (May 2005). "Determination of synthesis route of ... 149 (2-3): 181-92. doi:10.1016/j.forsciint.2004.06.016. PMID 15749360. PiHKAL ("Phenethylamines i Have Known And Loved") by ... The base compound of the MDxx class is 3,4-methylenedioxyphenethylamine (MDPEA), and the prototypical agent of this class is 3, ... 4-cyclised amphetamine core common to the MDxx compounds, but have the 1,3-benzodioxole ring replaced by related heterocycles. ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 41 (6): 1001-5. doi:10.1021/jm9705925. PMID 9526575.. ... 5-Methyl-3,4-methylenedioxyamphetamine (5-Methyl-MDA) is an entactogen and psychedelic designer drug of the amphetamine class. ... InChI=1S/C11H15NO2/c1-7-3-9(4-8(2)12)5-10-11(7)14-6-13-10/h3,5,8H,4,6,12H2,1-2H3 Y ... "Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-( ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 41 (6): 1001-5. CiteSeerX 10.1.1.688.9559. doi:10.1021/ ... 6-Methyl-3,4-methylenedioxyamphetamine (6-Methyl-MDA) is an entactogen and psychedelic drug of the amphetamine class. It was ... In animal studies it substitutes for MBDB, MMAI, LSD, and 2,5-dimethoxy-4-iodoamphetamine (DOI), though not amphetamine, but ... and 3,4-methylenedioxy-N-methylamphetamine (MDMA). 6-Methyl-MDA has IC50 values of 783 nM, 28,300 nM, and 4,602 nM for ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 41 (6): 1001-5. CiteSeerX 10.1.1.688.9559. doi:10.1021/ ... methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700-6. doi:10.1021/jm00075a027. PMID 8246240. Parker MA ... 3 (1-2): 3-10. Archived from the original on 2009-03-17. Retrieved 2009-08-06. Monte AP, Marona-Lewicka D, Cozzi NV, Nichols DE ... 5-(2-Aminopropyl)-2,3-dihydro-1H-indene (5-APDI), also known as indanylaminopropane (IAP), IAP (psychedelic), 2-API(2- ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 41 (6): 1001-5. doi:10.1021/jm9705925. PMID 9526575. PIHKAL ... 5-Methyl-3,4-methylenedioxyamphetamine (5-Methyl-MDA) is an entactogen and psychedelic designer drug of the amphetamine class. ... 325 (3): 791-800. doi:10.1124/jpet.108.136200. PMC 2637348. PMID 18354055. Convention on Psychotropic Substances, 1971 §1308.11 ... "Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-( ...
... methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 41 (6): 1001-5. CiteSeerX 10.1.1.688.9559. doi:10.1021/ ... 2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen[citation needed] and psychedelic[citation needed] drug ... "Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-( ...
... methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700-6. doi:10.1021/jm00075a027. PMID 8246240. Nichols, ... 6-APDB is an analogue of 5-APDB where the 4-position oxygen has been replaced by a methylene bridge instead. 5-APDB was ... 29 (2): 302-4. doi:10.1021/jm00152a022. PMID 3950910. Nichols, DE; Snyder, SE; Oberlender, R; Johnson, MP; Huang, XM (1991). "2 ... 4 Jun 2013. Retrieved 2013-06-13. "'NBOMe' and 'Benzofury' banned". UK Home Office. 4 Jun 2013. Retrieved 2013-06-13.. ...
... methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700-6. doi:10.1021/jm00075a027. PMID 8246240. UK Home ... 5-APDB (3-Desoxy-MDA) is an analogue of 6-APDB where the 3-position oxygen has been replaced with a methylene instead. 6-APDB, ... It is an analogue of MDA where the heterocyclic 4-position oxygen from the 3,4-methylenedioxy ring has been replaced with a ... 6-(2-Aminopropyl)-2,3-dihydrobenzofuran (6-APDB, 4-Desoxy-MDA, EMA-3) is a stimulant and entactogen drug of the phenethylamine ...
... methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700-6. doi:10.1021/jm00075a027. PMID 8246240. "Temporary ... 5-MAPDB (1-(2,3-dihydrobenzofuran-5-yl)-N-methylpropan-2-amine) is a chemical compound which acts as an entactogenic drug. It ...
... methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700-6. doi:10.1021/jm00075a027. PMID 8246240. Ann ... This parallels Alexander Shulgin's finding that EDMA (the 1,4-benzodioxine analogue of 6-APT) is inactive, and appears to ...
... methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700-6. doi:10.1021/jm00075a027. PMID 8246240. US patent ... 5 (4): 270-6. doi:10.1002/dta.1451. PMID 23349125. Nichols DE, Hoffman AJ, Oberlender RA, Riggs RM (February 1986). "Synthesis ... 29 (2): 302-4. doi:10.1021/jm00152a022. PMID 3950910. Nichols DE, Snyder SE, Oberlender R, Johnson MP, Huang XM (January 1991 ... 35 (11): 2061-4. doi:10.1021/jm00089a017. PMID 1534585. Monte AP, Marona-Lewicka D, Cozzi NV, Nichols DE (November 1993). " ...
5-methylenedioxy amphetamine, a new psychotomimetic agent". Nature 201: 1120-1121. 29 ... ISBN 1-889725-01-3.. .. *. with Shulgin, Ann (1997). TIHKAL: The Continuation. Berkeley: Transform Press. ISBN 0-9630096-9-9.. ... ISBN 978-0-9630096-3-0.. .. *. with Perry, Wendy (2002). The Simple Plant Isoquinolines. Berkeley: Transform Press. ISBN 0- ... Pp 3-26. 65. *1971. "Preliminary studies of the synthesis of nitrogen analogs of Delta1-THC". Acta Pharm. Suec. 8: 680-681. 66 ...
323 (2-3): 173-80. doi:10.1016/S0014-2999(97)00044-7. PMID 9128836. Conway EL, Louis WJ, Jarrott B (December 1978). "Acute and ... 52 (3-4): 271-80. doi:10.1016/0014-2999(78)90279-0. PMID 729639. Welter J, Kavanagh P, Meyer MR, Maurer HH (February 2015). " ... 4 Jun 2013. Retrieved 2013-07-10. "Schedule I". Government Of Canada. 2014-12-12. Archived from the original on 2013-11-22. ... A study in rats indicated that the major metabolites of 5-MAPB are 5-APB and 3-carboxymethyl-4-hydroxymethamphetamine. 5-MAPB ...
52 (3-4): 271-80. doi:10.1016/0014-2999(78)90279-0. PMID 729639. Miller RT, Lau SS, Monks TJ (April 1997). "2,5-Bis-(glutathion ... 1991), demonstrated that the major metabolites alpha-methyldopamine (α-Me-DA or HHA) and 3-O-methyl-α-methyldopamine (3-O-Me-α- ... α-Methyldopamine (α-Me-DA), also known as 3,4-dihydroxyamphetamine (3,4-DHA or HHA), is a research chemical of the ... α-Methylnorepinephrine α-Methyltyramine McCann UD, Ricaurte GA (April 1991). "Major metabolites of (+/-)3,4- ...
Methylenedioxyamphetamine (MDA; Tenamfetamine) • Methylenedioxyethylamphetamine (MDEA) • Methylenedioxyhydroxyamphetamine (MDOH ... 5-chloro-1-(1-[3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl]piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one ... doi:10.1016/S0149-2918(98)80054-4. பப்மெட்:9663360. *↑ பாலூட்டும் பெண்களுக்கான டோம்பரிடோன் , கனடிய மெடிகல் அசோசியேசன் இதழ், ... 5-HT3 Antagonists. Alosetron • Azasetron • Bemesetron • Cilansetron • Clozapine • Dazopride • Dolasetron • Granisetron • ...
Primarily: MAO-B[3][4][5]. Other enzymes: MAO-A,[5][6] SSAOs (AOC2 & AOC3),[5][7] PNMT,[3][4][5] AANAT,[5] FMO3,[8][9] and ... Primarily: MAO-B[3][4][5]. Other enzymes: MAO-A,[5][6] SSAOs (AOC2 & AOC3),[5][7] PNMT,[3][4][5] AANAT,[5] FMO3,[8][9] and ... 11 (4): 481-524. PMID 9160.. *^ a b Berry, MD (July 2004). "Mammalian central nervous system trace amines. Pharmacologic ... 313 (3): 263-8. doi:10.1007/BF00505743. PMID 7432557.. *^ "EC 2.3.1.87 - aralkylamine N-acetyltransferase". BRENDA. Technische ...
EA 1298 - Methylenedioxyamphetamine (MDA), an analogue and active metabolite of MDMA. *EA 1475 - Methylenedioxymethamphetamine ... VP - (3-pyridyl 3,3,5-trimethylcyclohexyl methylphosphonate) [EA1511][3]. *VR - VR nerve agent (O-isobutyl S-(2-diethaminoethyl ... A CB weapon is an integrated device of (1) agent, (2) dissemination means, and (3) delivery system. ...
3-Methoxy-4-hydroxyphenylglycol(英語:3-Methoxy-4-hydroxyphenylglycol). *Dihydroxyphenylethylene glycol(英語:Dihydroxyphenylethylene ... 維基媒體基金會是在美國佛羅里達州登記的501(c)(3)免稅、非營利、慈善機構。. ... 人腦中兒茶酚胺&痕量胺的合成路徑[1][2][3] ... 4-甲基苯乙胺(英語:4-Methylphenethylamine). *β-甲基
4-Methoxyamphetamine. References[edit]. *^ a b c Shulgin, Alexander; Ann Shulgin (September 1991). PiHKAL: A Chemical Love ... History: 2,5-DMA was first synthesized in Tuckahoe, New York by Richard Baltzly and Johannes S. Buck in 1939.[3] ... History: Experiments on psychiatric patients who were given 3,4-DMA at dosages of 70 mg to 700 mg by IV injection took place at ... The isomers are 2,3-DMA, 2,4-DMA, 2,5-DMA, 2,6-DMA, 3,4-DMA, and 3,5-DMA. They were first collectively characterized by ...
... ("3,4-MDPEA" or just "MDPEA"), also known as homopiperonylamine, is a substituted ... 5-methylenedioxyamphetamine. *2C-B. *3C-BZ. *2C-C. *2C-D ... Retrieved from "https://en.wikipedia.org/w/index.php?title=3,4- ... InChI=1S/C9H11NO2/c10-4-3-7-1-2-8-9(5-7)12-6-11-8/h1-2,5H,3-4,6,10H2 ...
... ("MDEA"; also called "MDE" and colloquially, "Eve") is an empathogenic psychoactive drug ... 3,4-Methylenedioxy-N-ethylamphetamine. From Wikipedia, the free encyclopedia. (Redirected from 3,4-methylenedioxy-N- ... 106 MDE: MDEA; EVE; N-Ethyl-MDA; 3,4-Methylenedioxy-N-ethylamphetamine". Isomer Design. Retrieved 10 December 2014.. ... Freudenmann RW, Spitzer M (2004). "The Neuropsychopharmacology and Toxicology of 3,4-methylenedioxy-N-ethyl-amphetamine (MDEA ...
83 (3): 469-72. PMID 29319947.. *^ a b c d e f g Drug Enforcement Administration, Department of Justice (2018). "Schedules of ... 4-Chloro-alpha-pyrrolidinovalerophenone (4-chloro-α-PVP)[20] 1233 3-Fluoro-N-methylcathinone (3-FMC; 1-(3-fluorophenyl)-2-( ... N-(1-phenethylpiperidin-4-yl)-N-phenylpentanamide (valeryl fentanyl)[15] 9823 N-(4-fluorophenyl)N-(1-phenethylpiperidin-4-yl) ... Additional substances are added to the list by the Secretary of Health and Human Services pursuant to 21 CFR 1308.49.[4][5] ...
... (DOPR) is a psychedelic drug of the phenethylamine and amphetamine chemical classes. It was ... InChI=1S/C15H25NO2/c1-5-6-11-8-14(17-4)12(7-10(2)15)9-13(11)16-3/h8-10H,5-7,15H2,1-4H3 N ... The alternative structural isomer DOIP, with a 4-isopropyl substitution, is also known but is around ten times weaker than DOPR ... 5-methylenedioxyamphetamine. *2C-B. *3C-BZ. *2C-C. *2C-D ... 5-HT3. *Agonists: Alcohols (e.g., butanol, ethanol (alcohol), ...
InChI=1S/C12H19NO2/c1-9(13-2)7-10-8-11(14-3)5-6-12(10)15-4/h5-6,8-9,13H,7H2,1-4H3 Y ... 5-methylenedioxyamphetamine. *2C-B. *3C-BZ. *2C-C. *2C-D ...
... (MDMP), or 3,4-methylenedioxy-α,α,N-trimethylphenethylamine, is a lesser-known ... 5-methylenedioxyamphetamine. *2C-B. *3C-BZ. *2C-C. *2C-D ... 4-Methylenedioxy-N-methylphentermine. From Wikipedia, the free ... Retrieved from "https://en.wikipedia.org/w/index.php?title=3,4-Methylenedioxy-N-methylphentermine&oldid=846480831" ...
... (MDMEO, MDMEOA, or MDMeOA) is a lesser-known psychedelic drug and a substituted ... InChI=1S/C11H15NO3/c1-8(12-13-2)5-9-3-4-10-11(6-9)15-7-14-10/h3-4,6,8,12H,5,7H2,1-2H3 Y ... 5-methylenedioxyamphetamine. *2C-B. *3C-BZ. *2C-C. *2C-D ... Retrieved from "https://en.wikipedia.org/w/index.php?title=3,4- ... InChI=1/C11H15NO3/c1-8(12-13-2)5-9-3-4-10-11(6-9)15-7-14-10/h3-4,6,8,12H,5,7H2,1-2H3 ...
... is also a controlled substance in Argentina as well as 2C-B and 2C-I.[3] ... InChI=1S/C12H19NO2S/c1-4-16-12-8-10(14-2)9(5-6-13)7-11(12)15-3/h7-8H,4-6,13H2,1-3H3 Y ... Theobald, DS; R Staack; M Puetz; HH Mauer (September 2005). "New designer drug 2,5-dimethoxy-4-ethylthio-β-phenethylamine (2C-T ... As of October 31, 2016, 2C-T-2 is a controlled substance (Schedule III) in Canada.[4] ...
... methylenedioxyamphetamine 亞甲二氧甲基苯丙胺(MDMA). CH3. -O-CH2-O-. CH3. 3,4-methylenedioxy-N-methylamphetamine ... C(CH3)3. 3-chloro-N-tert-butyl-β-ketoamphetamine 芬氟拉明(氟苯丙胺,Fenfluramine). CH3. CF3. CH2CH3. 3-trifluoromethyl-N-ethyl- ... OCH3. CH3. OCH3. 2,5-dimethoxy-4-methylamphetamine 布苯丙胺(二甲氧基溴安非他明,DOB,Brolamfetamine,Bromo-DMA). CH3. OCH3. Br. OCH3. 2,5- ... 苯乙胺的注入會提升細胞外液中多
烏羽玉含有精神生物鹼,如麥司卡林(三甲氧苯乙胺[3])等,故被用在宗教致幻劑及多種宗教超越上,包括冥想及迷幻藥治療法等。美國原住民很久以前就已經使用烏羽玉作為儀式及醫藥用途。烏羽玉於3月至5月間開花,有時會開至9月。其花朵是粉紅色的,花藥有趨觸性。 ... 烏
0 1 2 3 4 5 6 7 8 9 • A Aa Ae Aj Ao At • B Ba Be Bj Bo Bt • C Ca Ce Cj Co Ct • D Da De Dj Do Dt • E Ea Ee Ej Eo Et • F Fa Fe Fj ... 5-methylenedioxyamphetamine. *Talk:2-Diphenylmethylpyrrolidine. *Talk:2-Fluorodeschloroketamine ...
MEPEA, or 3-methoxy-4-ethoxyphenethylamine, is a lesser-known psychedelic drug. MEPEA was first synthesized by Alexander ... InChI=1S/C11H17NO2/c1-3-14-10-5-4-9(6-7-12)8-11(10)13-2/h4-5,8H,3,6-7,12H2,1-2H3 Y ... 5-methylenedioxyamphetamine. *2C-B. *3C-BZ. *2C-C. *2C-D ... Retrieved from "https://en.wikipedia.org/w/index.php?title=3- ... InChI=1/C11H17NO2/c1-3-14-10-5-4-9(6-7-12)8-11(10)13-2/h4-5,8H,3,6-7,12H2,1-2H3 ...
MEE (2-methoxy-4,5-diethoxyamphetamine) is a lesser-known psychedelic drug of the amphetamine class. It is a diethoxy-methoxy ... InChI=1S/C14H23NO3/c1-5-17-13-8-11(7-10(3)15)12(16-4)9-14(13)18-6-2/h8-10H,5-7,15H2,1-4H3 Y ... 5-methylenedioxyamphetamine. *2C-B. *3C-BZ. *2C-C. *2C-D ...
5-methylenedioxyamphetamine (5-Methyl-MDA). *3,4-Ethylenedioxy-N-methylamphetamine (EDMA) ... doi:10.1016/S0028-3908(99)00023-4. PMID 10428424.. *^ a b Blough BE, Landavazo A, Decker AM, Partilla JS, Baumann MH, Rothman ... 9 (3-4): 299-312. PMID 8400010.. *. Marona-Lewicka D, Nichols DE (December 1997). "The Effect of Selective Serotonin Releasing ... The designer drug 4-methylaminorex, which is an SNDRA and 5-HT2B agonist, has been reported to cause this effect as well. ...
Low-moderate[3][4]. Routes of. administration. Common: by mouth[5]. Uncommon: snorting,[5] inhalation (vaporization),[5] ... "3,4-Methylenedioxymethamphetamine". Hazardous Substances Data Bank. National Library of Medicine. 28 August 2008. ശേഖരിച്ചത് 22 ... InChI=1S/C11H15NO2/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10/h3-4,6,8,12H,5,7H2,1-2H3 Y ... 5-methylenedioxyamphetamine. *2C-B. *3C-BZ. *2C-C. *2C-D ... 5-HT3. *Agonists: Alcohols (e.g., butanol, ethanol (alcohol), ...
InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1 Y. Key: QIVBCDIJIAJPQS- ... InChI=1/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1. Key: QIVBCDIJIAJPQS- ... Agonists: Lysergamides: ALD-52 • Ergometrine • Lisuride • Lysergic acid 2,4-dimethylazetidide • ال‌اس‌دی • LSD-Pip • Lysergic ... Tryptophan or (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... 4-Methyl-AMT • 5-Carboxamidotryptamine • 5-MeO-AET • 5-MeO-AMT ...
DOB was first synthesized by Alexander Shulgin in 1967.[2][3] Its synthesis and effects are documented in Shulgin's book PiHKAL ... The full name of the chemical is 2,5-dimethoxy-4-bromoamphetamine. DOB has a stereocenter and R-(-)-DOB is the eutomer. This is ... InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3 Y ... Shulgin, A.T.; Sargent, T.; Naranjo, C. (1971). "4-Bromo-2,5-Dimethoxyphenylisopropylamine, a New Centrally Active Amphetamine ...
5-methylenedioxyamphetamine). *DOB. *DOB-FLY(英语:DOB-FLY) ... DMT也存在于一些植物当中(例如死藤水[a]、相思樹的樹皮[2][3])。在部分领域当中,DMT被认为是一种可以打开人类潜能的物质[4]。 ... 5-MeO-4,N,N-TMT(英语:5-MeO-4,N,N-TMT) ... 4-Acetoxy-DALT(英语:4-AcO-DALT). *4-Acetoxy-DET(
Clinical Pharmacology of MDA [3,4-methylenedioxyamphetamine] (MDA). The safety and scientific validity of this study is the ... Clinical Pharmacology of MDA [3,4-methylenedioxyamphetamine] Brief Summary The purpose of this study is to investigate the ... Clinical Pharmacology of MDA [3,4-methylenedioxyamphetamine] Official Title ICMJE ... Investigating the mechanisms of hallucinogen-induced visions using 3,4-methylenedioxyamphetamine (MDA): a randomized controlled ...
3,4-Methylenedioxyamphetamine. Clinical Trials. Clinical Trials Not Available. Pharmacoeconomics. Manufacturers. Not Available ... 4764-17-4. Weight. Average: 179.2157 Monoisotopic: 179.094628665 Chemical Formula. C10H13NO2. InChI Key. NGBBVGZWCFBOGO- ... 3,4-Methylenedioxyamphetamine may decrease the sedative activities of Bamipine.. Experimental. Benmoxin. Benmoxin may increase ... 3,4-Methylenedioxyamphetamine may increase the analgesic activities of Levorphanol.. Approved. Lithium. Lithium may decrease ...
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5-methylenedioxyamphetamine · 2C-B · 3C-BZ · 2C-C · 2C-D · 2C-E · 3C-E · 2C-F · 2C-G · 2C-G-3 · 2C-G-4 · 2C-G-5 · 2C-G-N · 2C-H ... 2C-I · 2C-N · 2C-O · 2C-O-4 · 2C-P · CPM · 2C-SE · 2C-T · 2C-T-2 · 2C-T-4 · psi-2C-T-4 · 2C-T-7 · 2C-T-8 · 2C-T-9 · 2C-T-13 · ... 3-TE · 4-TE · 3-TIM · 4-TIM · 5-TIM · 3-TM · 4-TM · TMA · TMA-2 · TMA-3 · TMA-4 · TMA-5 · TMA-6 · 3-TME · 4-TME · 5-TME · 2T- ... AEM · AL · Aleph · Aleph-2 · Aleph-4 · Aleph-6 · Aleph-7 · Ariadne · Asymbescaline · Buscaline · Beatrice · Bis-TOM · BOB · BOD ...
We determined the prevalence and risk factors for 3,4-methylenedioxy-methamphetamine [‎MDMA, "ecstasy"]‎ use among college ...
Definition of 3,4-Methylenedioxyamphetamine in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... What is 3,4-Methylenedioxyamphetamine? Meaning of 3,4-Methylenedioxyamphetamine as a finance term. What does 3,4- ... are all methylenedioxyamphetamine derivatives (Fig.. Determination of the designer drugs 3,4-Methylenedioxymethamphetamine, 3,4 ... redirected from 3,4-Methylenedioxyamphetamine). Also found in: Dictionary, Medical, Acronyms, Encyclopedia, Wikipedia. MDA. See ...
Distribution Study of 3,4-Methylenedioxymethamphetamine and 3,4-Methylenedioxy-amphetamine in a Fatal Overdose Journal of ... "CASE REPORT: Distribution Study of 3,4-Methylenedioxymethamphetamine and 3,4-Methylenedioxy-amphetamine in a Fatal Overdose". ... In this study, regional tissue distributions of the amphetamine analogue 3,4-methylenedioxymethamphetamine (MDMA, �ecstasy�) ... 4-Methylenedioxy-amphetamine in a Fatal Overdose" Journal of Analytical Toxicology. 2002 Mar;26(2):113-8. ...
... and acute toxicity of some N-alkyl derivatives of 3,4-methylenedioxyamphetamine J Assoc Off Anal Chem 1987 70(6):981-6 ... A series of N-alkyl derivatives of 3,4-methylenedioxyamphetamine (MDA) was prepared in an effort to characterize these ... "Synthesis, identification, and acute toxicity of some N-alkyl derivatives of 3,4-methylenedioxyamphetamine". ... "Synthesis, identification, and acute toxicity of some N-alkyl derivatives of 3,4-methylenedioxyamphetamine" J Assoc Off Anal ...
De Souza EB 3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: ... 1987;242(3):911-6.. Battaglia G, Yeh SY, OHearn E, Molliver ME, Kuhar MJ, De Souza EB. "3,4-Methylenedioxymethamphetamine and ... This study examines the effects of repeated systemic administration (20 mg/kg s.c., twice daily for 4 days) of 3,4- ... "3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of ...
Definition of n-methyl-3,4-methylenedioxyamphetamine in the Definitions.net dictionary. Meaning of n-methyl-3,4- ... methylenedioxyamphetamine. What does n-methyl-3,4-methylenedioxyamphetamine mean? Information and translations of n-methyl-3,4- ... methylenedioxyamphetamine in the most comprehensive dictionary definitions resource on the web. ... Discuss these n-methyl-3,4-methylenedioxyamphetamine definitions with the community:. Word of the Day. Would you like us to ...
... and 3,4-methylenedioxyethylamphetamine in urine by solid-phase extraction and GC-MS: A method optimized for high-volume lab. ... and 3,4-methylenedioxyethylamphetamine in urine by solid-phase extraction and GC-MS: A method optimized for high-volume ... 2002). Rapid simultaneous determination of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 3,4- ... Rapid simultaneous determination of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 3,4- ...
3,4-Methylenedioxyamphetamine (MDA) and 3,4-methyl-enedioxymethamphetamine (MDMA, ecstasy) are widely abused amphetamine ... ABBREVIATIONS: MDA, 3,4-methylenedioxyamphetamine; MDMA, 3,4-methylenedioxymethamphetamine (ecstasy); 5-HT, 5-hydroxytryptamine ... Thioether Metabolites of 3,4-Methylenedioxyamphetamine and 3,4-Methylenedioxymethamphetamine Inhibit Human Serotonin ... Thioether Metabolites of 3,4-Methylenedioxyamphetamine and 3,4-Methylenedioxymethamphetamine Inhibit Human Serotonin ...
... methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700-3706. doi:10.1021/jm00075a027. PMID 8246240. Baggott ... 17 (4): 359-364. doi:10.1159/000137100. PMID 5631047. Yensen, R.; Di Leo, F. B.; Rhead, J. C.; Richards, W. A.; Soskin, R. A.; ... In addition to 3,4-methylenedioxyamphetamine, MDA is also known by other chemical synonyms such as the following: α-Methyl-3,4- ... 69 (4): 681-686. PMID 2875058. Mannich, C.; Jacobsohn, W.; Mannich, Hr. C. (1910). "Über Oxyphenyl-alkylamine und Dioxyphenyl- ...
... (MDA). In animal studies, MDAI effects are indistinguishable from 3 ... methylenedioxy)amphetamine (MDA). In animal studies, MDAI effects are indistinguishable from 3,4-(methylenedioxy) ...
Buy MDAI is an indane analog of 3,4-(methylenedioxy)amphetamine (MDA). In animal studies, MDAI effects are indistinguishable ... methylenedioxy)amphetamine (MDA). In animal studies, MDAI effects are indistinguishable from 3,4-(methylenedioxy) ...
Methylenedioxyamphetamine - HFBA Compound Information and Applications for GC (Gas Chromatography) and LC (Liquid ... Methylenedioxyamphetamine; 3,4-MDA HCl; Tenamfetamine; Phenethylamine, α-methyl-3,4-(methylenedioxy)-; 1,3-Benzodioxole-5- ... ethanamine, α-methyl-; α-Methyl-3,4-(methylenedioxy)phenethylamine; (.+/-.)-3,4-Methylenedioxyamphetamine ...
3 (1-2): 28. Retrieved 9 October 2013.. *^ Lancashire, Robert J. (13 October 2011). "Unit 9: Crime - Reagent Kits". University ... 2,5-Dimethoxy-4-bromoamphetamine (DOB). Olive Green - Yellow 2-FMA. Rapidly fizzes and dissolves. Colourless/Light yellow[ ... Final colors produced by Marquis Reagent with various substances[1]:3-6[8] Substance Color ... 3] in his magister dissertation in 1896;[4] and named after him,[5] and was tested for the first time at the University of ...
N-Formyl-3,4-methylenedioxyamphetamine. 50 mg. NMIAD498. Add to basket 1,2-Dimethoxy-4-(2-propenyl)-benzene. 25 mg. NMIAD885. ... 3,4-Methylenedioxybenzyl methyl ketoximine. 10 mg. NMIAD890. Add to basket alpha-Acetylphenylacetonitrile DRUG PRECURSOR. 20 mg ... bis-(1-(3,4-Methylenedioxyphenyl)-propan-2-yl)amine HCl (mix of isomers). 20 mg. NMIAD879. Add to basket ... bis-(1-(3,4-Methylenedioxyphenyl)-propan-2-yl)amine HCl (1 diastereoisomer). 20 mg. NMIAD896. Add to basket ...
DATES: Registered bulk manufacturer of the affected basic class(es), and applicants therefore, may file written comments on or objections to the issuance of the proposed registration on or before May 21, 2020. Such persons may also file a written request for a hearing on the application on or before May 21, 2020.. ADDRESSES: Written comments should be sent to: Drug Enforcement Administration, Attention: DEA Federal Register Representative/DPW, 8701 Morrissette Drive, Springfield, Virginia 22152. All requests for a hearing must be sent to: Drug Enforcement Administration, Attn: Administrator, 8701 Morrissette Drive, Springfield, Virginia 22152. All requests for a hearing should also be sent to: (1) Drug Enforcement Administration, Attn: Hearing Clerk/OALJ, 8701 Morrissette Drive, Springfield, Virginia 22152; and (2) Drug Enforcement Administration, Attn: DEA Federal Register Representative/DPW, 8701 Morrissette Drive, Springfield, Virginia 22152.. SUPPLEMENTARY INFORMATION: In accordance with 21 ...
The firm plans to manufacture the listed controlled substances to supply their customers.. Any other such applicant and any person who is presently registered with DEA to manufacture such substances may file comments or objections to the issuance of the proposed registration.. Any such comments or objections may be addressed, in quintuplicate, to the Deputy Assistant Administrator, Office of Diversion Control, Drug Enforcement Administration, United States Department of Justice, Washington, DC 20537, Attention: DEA Federal Register Representative (CCR), and must be filed no later than March 12, 2001.. Start Signature ...
In accordance with 21 CFR 1301.33(a), this is notice that on February 1, 2016, Sigma Aldrich Research Biochemicals, Inc., 1-3 ...
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4. The name of the prescribing practitioner.. 5. The name of the patient for whom, or of the owner and species of the animal ... 3) A person in charge of a hospital or laboratory or in the employ of this state or of any other state, or of any political ... 4) SCHEDULE IV.-A substance in Schedule IV has a low potential for abuse relative to the substances in Schedule III and has a ... 2) 1,4-Butanediol is excepted from scheduling pursuant to s. 893.03(1)(d)1. when that substance is in the possession of:. (a) A ...
14a) The term isomer means, except as used in G.S. 90-87(17)(d), G.S. 90-89(c), G.S. 90-90(1)d., and G.S. 90-95(h)(3), the ... 3) The provisions of this subsection may be utilized by the State only if:. a. The State notifies the defendant at least 15 ... 4-7; 1983, c. 18; c. 294, s. 6; c. 414; 1985, c. 569, s. 1; c. 675, ss. 1, 2; 1987, c. 90; c. 105, ss. 4, 5; c. 640, ss. 1, 2; ... 3) Limit or abridge the authority of a law enforcement officer to detain or take into custody a person in the course of an ...
The firm plans to produce small quantities of controlled substances for use in drug test kits.. Any other such applicant and any person who is presently registered with DEA to manufacture such substances may file comments or objections to the issuance of the proposed registration.. Any such comments or objectives may be addressed, in quintuplicate, to the Deputy Assistant Administrator, Office of Diversion Control, Drug Enforcement Administration, United States Department of Justice, Washington, DC 20537, Attention: Federal Register Representative, Office of Chief Counsel (CCD) and must be filed no later than February 2, 2004.. Start Signature ...
4) SCHEDULE IV.-A substance in Schedule IV has a low potential for abuse relative to the substances in Schedule III and has a ... 88-59; s. 3, ch. 89-281; s. 54, ch. 92-69; s. 1, ch. 93-92; s. 4, ch. 95-415; s. 1, ch. 96-360; ss. 1, 5, ch. 97-1; s. 96, ch. ... 3) SCHEDULE III.-A substance in Schedule III has a potential for abuse less than the substances contained in Schedules I and II ... 1-Butyl-3-(1-naphthoyl)indole, also known as JWH-073.. 50. 1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl) indole, also known as JWH ...
extract as antiestrogen receptor (-) breast cancer cell line 3,4-methylenedioxyamphetamine-MB-231 by molecular docking and 3-(4 ...
2008 Mar;38(3):464-73. Epub 2007 Nov 8. Cami J, Farré M, Mas M, Roset PN, Poudevida S, Mas A, San L, de la Torre R. Human ... Epub 2012 Dec 3. Dziobek I, Rogers K, Fleck S, Bahnemann M, Heekeren HR, Wolf OT, Convit A. Dissociation of cognitive and ... 2000 Aug;20(4):455-66. Dumont GJ, Verkes RJ. A review of acute effects of 3,4-methylenedioxymethamphetamine in healthy ... 1998 Oct;19(4):241-51. Liechti ME, Gamma A, Vollenweider FX. Gender differences in the subjective effects of MDMA. ...
doi: 10.1007/s00213-020-05548-2. Epub 2020 Jun 4. Feduccia AA, Jerome L, Yazar-Klosinski B, Emerson A, Mithoefer MC, Doblin R. ... N-Methyl-3,4-methylenedioxyamphetamine. Hallucinogens. Physiological Effects of Drugs. Psychotropic Drugs. Serotonin Agents. ... Columbia Suicide Severity Rating Scale (C-SSRS) [ Time Frame: Phone contact days 2 and 7 after experimental session 3 ]. A ... Randomized, Triple-Blind, Phase 2 Pilot Study Comparing 3 Different Doses of MDMA in Conjunction With Manualized Psychotherapy ...
4)(a) SCHEDULE IV.-A substance in Schedule IV has a low potential for abuse relative to the substances in Schedule III and has ... 88-59; s. 3, ch. 89-281; s. 54, ch. 92-69; s. 1, ch. 93-92; s. 4, ch. 95-415; s. 1, ch. 96-360; ss. 1, 5, ch. 97-1; s. 96, ch. ... 3) SCHEDULE III.-A substance in Schedule III has a potential for abuse less than the substances contained in Schedules I and II ... VII) RCS-4 C4 homologue (1-Butyl-3-(4-methoxybenzoyl)indole).. (VIII) AM-630 (1-[2-(4-Morpholinyl)ethyl]-2-methyl-6-iodo-3-(4- ...
  • In relation to other phenethylamines and amphetamines, it is the 3,4-methylenedioxy, α-methyl derivative of β-phenylethylamine, the 3,4-methylenedioxy derivative of amphetamine, and the N-desmethyl derivative of MDMA. (wikipedia.org)
  • We determined the prevalence and risk factors for 3,4-methylenedioxy-methamphetamine [‎MDMA, "ecstasy"]‎ use among college students in Astara, a northern border city of Iran. (who.int)
  • In this study, regional tissue distributions of the amphetamine analogue 3,4-methylenedioxymethamphetamine (MDMA, �ecstasy�) and its metabolite 3,4-methylenedioxyamphetamine (MDA) in a fatal overdose are presented. (erowid.org)
  • This study examines the effects of repeated systemic administration (20 mg/kg s.c., twice daily for 4 days) of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on levels of brain monoamines, their metabolites and on the density of monoamine uptake sites in various regions of rat brain. (erowid.org)
  • In contrast, neither MDMA nor MDA caused any widespread or long-term changes in the content of the catecholaminergic markers (i.e., norepinephrine, dopamine, 3,4 dihydroxyphenylacetic acid and homovanillic acid) or in the number of [3H]mazindol-labeled norepinephrine or dopamine uptake sites in the brain regions examined. (erowid.org)
  • 3,4-Methylenedioxyamphetamine (MDA) and 3,4-methyl-enedioxymethamphetamine (MDMA, ecstasy) are widely abused amphetamine derivatives that target the serotonin system. (aspetjournals.org)
  • In animal studies, MDAI effects are indistinguishable from 3,4-(methylenedioxy)methamphetamine (MDMA). (healthplusrc.com)
  • The drug 3,4 methylenedioxymethamphetamine (MDMA), also known as "ecstasy," is a "designer" drug that is becoming popular with American adolescents at dance halls known as "raves" and on college campuses. (aappublications.org)
  • In particular, neuroadaptations within corticolimbic brain structures that mediate incentive learning and motivated behavior have been demonstrated after chronic exposure to cocaine, d-amphetamine, and 3,4-methylenedioxymethamphetamine (MDMA). (nih.gov)
  • The cardiovascular and neuroendocrine effects and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") were assessed in a double-blind, randomized, crossover, and controlled (placebo and amphetamine) clinical trial. (aspetjournals.org)
  • Between 8 and 9% of the doses of MDMA appeared in plasma in the form of 3,4-methylenedioxyamphetamine. (aspetjournals.org)
  • MDMA (3,4-methylenedioxy-N-methylamphetamine) is an empathogenic drug of the phenethylamine and amphetamine classes of drugs. (pearltrees.com)
  • 3] MDMA can induce euphoria, a sense of intimacy with others, diminished anxiety, and mild psychedelia. (pearltrees.com)
  • Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder, anxiety associated with terminal cancer[4][5] and addiction. (pearltrees.com)
  • Ecstasy (MDMA, 3,4-methylenedioxymethamphetamine) is commonly used by college-aged individuals. (asnjournals.org)
  • Ecstasy (3,4-methylenedioxymethamphetamine [MDMA]) is a synthetic drug that has found widespread use in young adult populations ( 1 , 2 ). (asnjournals.org)
  • In 1985, the US Drug Enforcement Agency placed MDMA on schedule I of controlled substances, thereby restricting its use ( 4 ). (asnjournals.org)
  • This move was triggered from reports showing that the administration of a related analogue (a metabolite of MDMA, methylenedioxyamphetamine [MDA]) caused damage to serotonergic nerve terminals in rat brains and that the drug has a high abuse potential ( 4 ). (asnjournals.org)
  • 3,4-Methylenedioxymethamphetamine (MDMA) and related compounds on their effects on neurotransmitters and hormones. (asnjournals.org)
  • SAMHSA also established new testing criteria for the drug metabolites, adding hydromorphone, oxymorphone, and methylenedioxyamphetamine (MDA) (a metabolite of Ecstasy or MDMA). (thermofisher.com)
  • Subjective and hormonal effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans. (drugabuse.gov)
  • Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity. (drugabuse.gov)
  • The Nature of 3, 4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonergic Dysfunction: Evidence for and Against the Neurodegeneration Hypothesis. (drugabuse.gov)
  • The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA) is a drug of abuse and has been shown to be neurotoxic to 5-HT terminals in many species. (jneurosci.org)
  • Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy. (semanticscholar.org)
  • This review of chronic tolerance to MDMA (3,4-methylenedioxymetamphetamine) covers the empirical data on dosage escalation, reduced subjective efficacy and bingeing in recreational Ecstasy users. (semanticscholar.org)
  • Repeated adolescent 3,4-methylenedioxymethamphetamine (MDMA) exposure in rats attenuates the effects of a subsequent challenge with MDMA or a 5-hydroxytryptamine(1A) receptor agonist. (semanticscholar.org)
  • They refer to a group of drugs that have a common phenethylamine structural backbone and include drugs such as amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA) and 3,4-Methylenedioxymethamphetamine (MDMA). (myhealth.gov.my)
  • 3,4-Methylenedioxy methamphetamine (MDMA) is metabolised to 3,4-methylenedioxyamphe tamine (MDA). (myhealth.gov.my)
  • Safrole is the main precursor for producing the amphetamine-type stimulant (ATS) drug, N -methyl-3,4-methylenedioxyamphetamine (MDMA), also known as ecstasy. (mdpi.com)
  • In particular, the abuse of N -methyl-3,4-methylenedioxyamphetamine (MDMA), well known as ecstasy, has been growing rapidly [ 1 ], despite its serious unhealthy side effects [ 2 ]. (mdpi.com)
  • The substance 3,4-methylenedioxymethamphetamine (MDMA [ie, ecstasy, XTC, Adam, E, X, clarity, Stacy, Molly]) is an amphetamine derivative that has gained significant popularity in recent years and has become the recreational drug of choice for many adolescents and young adults. (medscape.com)
  • In 1985, published reports stated that MDMA and its demethylated metabolite 3,4-methylenedioxyamphetamine (MDA) had long-term neurotoxic effects in laboratory animals. (medscape.com)
  • The method, named PPy-ESI-MS, was optimized for analysis of 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA) in synthetic urine. (rsc.org)
  • Studies were designed to examine the effects of dietary fats on metabolic effects of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy). (pubmedcentralcanada.ca)
  • Numerous ecstasy-related compounds have been described: 3,4-Methylenedioxyethamphetamine (MDEA, or "eve") and 3,4-methylenedioxyamphetamine (MDA, or "ice") ( 8 , 9 ). (asnjournals.org)
  • Novice users generally take a single Ecstasy tablet, regular users typically take 2-3 tablets, whereas the most experienced users may take 10-25 tablets in a single session. (semanticscholar.org)
  • Simultaneous chiral separation of 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxyamphetamine , 3,4-methylenedioxyethylamphetamine, ephedrine, amphetamine and methamphetamine by capillary electrophoresis in uncoated and coated capillaries with native R-cyclodextrin as the chiral selector: preliminary application to the analysis of urine and hair. (thefreedictionary.com)
  • Sassafras (methylenedioxyamphetamine) and molly (3,4-methylenedioxymethamphetamine) have a lot of similarities beyond their almost identical chemical names. (healthline.com)
  • Hatzidimitriou G, McCann UD, Ricaurte GA. Altered serotonin innervation patterns in the forebrain of monkeys treated with (+/-)3,4-methylenedioxymethamphetamine seven years previously: factors influencing abnormal recovery. (drugabuse.gov)
  • Stimulant and hallucinogenic behavioral profiles of 3,4-methylenedioxymethamphetamine and N-ethyl-3,4-methylenedioxyamphetamine in rats. (drugabuse.gov)
  • Peroutka SJ, Newman H, Harris H. Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users. (drugabuse.gov)
  • Effects of repeated 3,4-methylenedioxymethamphetamine administration on neurotransmitter efflux and sensory-evoked discharge in the ventral posterior medial thalamus. (semanticscholar.org)
  • The effects of Methamphetamine generally last 2-4 hours and the drug has a half-life of 9-24 hours in the body. (drugalcoholtest.com)
  • Methamphetamine is generally detectable in the urine for 3-5 days, depending on urine pH level. (drugalcoholtest.com)
  • However, one of its major metabolites, Benzoylecgonine, is found in the urine from up to a few days to 3 weeks for heavy users. (thermofisher.com)
  • Elevated levels of urinary metabolites are found within hours of exposure and remain detectable for 3-10 days after smoking. (drugalcoholtest.com)
  • In addition to 3,4-methylenedioxyamphetamine, MDA is also known by other chemical synonyms such as the following: α-Methyl-3,4-methylenedioxy-β-phenylethylamine 1-(3,4-Methylenedioxyphenyl)-2-propanamine 1-(1,3-Benzodioxol-5-yl)-2-propanamine MDA is typically synthesized from essential oils such as safrole or piperonal. (wikipedia.org)
  • 3,4-Methylenedioxyamphetamine ( MDA ) is a psychedelic , stimulant , and empathogen-entactogen of the phenethylamine and amphetamine chemical classes . (thefullwiki.org)
  • 3] It is probably the main contributor to the stimulant effect of Catha edulis. (pearltrees.com)
  • MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a stimulant and psychedelic drug of the amphetamine class. (drugbank.ca)
  • MMDA , or 3- methoxy -4,5- methylenedi oxy amphetamine , is a stimulant , a psychedelic drug, an entheogen , and an entactogen . (wikidoc.org)
  • MDAI can be produced from 3-(3,4-methylenedioxyphenyl)propionic acid [1] which is converted to the acid chloride and then heated to produce 5,6-Methylenedioxy-1-indanone. (wikipedia.org)
  • Methylenedioxybutylamphetamine ( MDBU or 3,4-methylenedioxy- N -butylamphetamine ) is a lesser-known psychedelic drug . (rug.nl)
  • 3,4-methylenedioxyamphetamine and 3,4-methylenedioxy-N-methylamphetamine adopt a high-affinity binding mode consistent with a transportable substrate, whereas MDDMA and MDTMA adopt a low-affinity binding mode consistent with an inhibitor, in which the ligand orientation is inverted. (nih.gov)
  • 1,3-Benzodioxolyl-N-methylbutanamine (N-methyl-1,3-benzodioxolylbutanamine, MBDB) is an entactogen of the phenethylamine chemical class. (pearltrees.com)
  • Wacker oxidation of safrole to yield 3,4-methylenedioxyphenylpropan-2-one (MDP2P) followed by reductive amination or via reduction of its oxime. (wikipedia.org)
  • Precursors commonly used to produce amphetamine-like drugs include piperonal, safrole, and iso-safrole [ 3 ]. (mdpi.com)
  • The erroneous association is due to MDA, 3,4-methylenedioxyamphetamine, a close analogue studied for its antidepressive and appetite suppressant effects developed in 1949-1957 by Smith, Kline, and French. (medscape.com)
  • It is also the N -butyl derivative of 3,4-methylenedioxyamphetamine (MDA). (rug.nl)
  • 8. 4-methyl-2, 5-dimethoxyamphetamine. (onenet.net)
  • 18. 4 Bromo-2, 5-dimethoxyamphetamine. (onenet.net)
  • 3. A method for the treatment of arthritis as claimed in claim 1, in which the member selected comprises 3,4-methylenedioxyamphetamine hydrochloride. (google.com)
  • 8. A method for the treatment of symptoms accompanying cast dermatitis as claimed in claim 6, in which the member selected comprises 3,4-methylenedioxyamphetamine hydrochloride. (google.com)
  • It has been determined that the administration of 3,4-methylenedioxyamphetamine (MDA) and its non-toxic acid addition salts, such as MDA hydrochloride (3,4-methylenedioxyamphetamine hydrochloride) will prevent and relieve swelling and pain which is associated with arthritis, for example, as may occur with joint fractures. (google.com)
  • 3,4-Methylene​dioxy​amphetamine (MDA), known commonly as sass, is an empathogen-entactogen, psychostimulant, and psychedelic drug of the amphetamine family that is encountered mainly as a recreational drug. (wikipedia.org)
  • Molecular model of the psychedelic drug MMDA (C11.H15.N.O3), also known as 3-methoxy-4,5-methylenedioxyamphetamine. (sciencephoto.com)
  • The serum concentration of 3,4-Methylenedioxyamphetamine can be decreased when it is combined with Ammonium chloride. (drugbank.ca)
  • The separation was carried out with an isocratic elution using the mobile phase of 3:15:82 (v/v/v) acetonitrile-methanol-ammonium acetate buffer (containing 7.5 × 10 −4 M TBAB, 0.8% (v/v) TEA and 1.0 × 10 −4 M ammonium acetate, pH 3.65) at a flow rate of 1.0 ml/min. (chemweb.com)
  • Then, group 2 received Ip saline, group 3 received Ip 3,4 - methylenedioxyamphetamine and group 4 received Ip ammonium platinum chloride. (ezinelocater.com)
  • A series of N-alkyl derivatives of 3,4-methylenedioxyamphetamine (MDA) was prepared in an effort to characterize these potential drugs of abuse. (erowid.org)
  • What does n-methyl-3,4-methylenedioxyamphetamine mean? (definitions.net)
  • Here are all the possible meanings and translations of the word n-methyl-3,4-methylenedioxyamphetamine . (definitions.net)
  • Are we missing a good definition for n-methyl-3,4-methylenedioxyamphetamine ? (definitions.net)
  • What rhymes with n-methyl-3,4-methylenedioxyamphetamine ? (definitions.net)
  • 1-(1-methyl-2-phenylethyl)-4-(N-propanilido) piperidine). (flsenate.gov)
  • 36. 1-Methyl-4-Phenyl-4-Propionoxypiperidine (MPPP). (flsenate.gov)
  • 3-methyl-1-(2-phenylethyl)-4-piperidyl]-N-phenylpropanamide). (flsenate.gov)
  • 36. Desmethylprodine (1-Methyl-4-Phenyl-4-Propionoxypiperidine). (flsenate.gov)
  • The risk or severity of hypertension can be increased when MMDA is combined with 1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid. (drugbank.ca)
  • The risk or severity of adverse effects can be increased when MMDA is combined with 3-isobutyl-1-methyl-7H-xanthine. (drugbank.ca)
  • In this study, we addressed this question directly by generating a series of N-substituted 3,4-methylenedioxyamphetamine analogs that differ only in the number of methyl substituents on the terminal amine group. (nih.gov)
  • Investigating the mechanisms of hallucinogen-induced visions using 3,4-methylenedioxyamphetamine (MDA): a randomized controlled trial in humans. (clinicaltrials.gov)
  • Small doses of 3,4 - methylenedioxyamphetamine may inhibit the action agencies of carbinoxamine. (ezinelocater.com)
  • Acetazolamide may decrease the excretion rate of 3,4-Methylenedioxyamphetamine which could result in a higher serum level. (drugbank.ca)
  • Homo sapiens RAB11 family interacting protein 4 (RAB11FIP4), transcript variant 1, mRNA. (ucsc.edu)
  • This invention relates to treatments for arthritis and cast dermatitis by the administration to patients of 3,4-methylenedioxyamphetamine and its non-toxic addition salts. (google.com)
  • 1. A method for the treatment of arthritis comprising administering to arthritics for the relief of symptoms accompanying arthritis a member selected from the group consisting of 3,4-methylenedioxyamphetamine and its non-toxic acid addition salts in dosage amounts of approximately 0.2 to 1.5 milligrams per kilogram of body weight. (google.com)
  • Our results suggest that the 3,4-methylenedioxyamphetamine analogs bind at the monoamine transporter orthosteric binding site by adopting one of two mutually exclusive binding modes. (nih.gov)
  • 3) 'Bureau' means the Bureau of Narcotics and Dangerous Drugs, United States Department of Justice or its successor agency. (ncleg.net)
  • Since 2010, the quantity of drugs seized globally has averaged around 4-5 tons. (mdpi.com)
  • There are many conventional analytical methods for detecting drugs, which are mainly chromatographic-based, such as gas chromatography (GC), liquid chromatography (LC), and liquid chromatography coupled with mass spectrometry (LC-MS) [ 4 , 5 ]. (mdpi.com)
  • In the late 90s, Alexander Shulgin changed his opinion of the duration to 3-6 hours). (thefullwiki.org)
  • 4. Alphacetylmethadol (except levo-alphacetylmethadol, also known as levo-alpha-acetylmethadol, levomethadyl acetate, or LAAM). (flsenate.gov)
  • Vojnosanit Pregl ;73(3):234-8, 2016 Mar. (bireme.br)
  • Parallel studies with [ 3 H]dopamine reveal a high negative correlation between inhibition of catalysis and incorporation of tritium into the enzyme. (jneurosci.org)
  • Those reducing agents and antioxidants that protect TPH from inactivation are effective in preventing the labeling of TPH by [ 3 H]dopamine. (jneurosci.org)
  • This is reduced to the 2-aminoindan following a modification of Nichols' earlier method from a paper discussing DOM analogues, [2] using a Pd/C catalyst in glacial acetic acid with catalytic H 2 SO 4 . (wikipedia.org)
  • The risk or severity of adverse effects can be increased when MMDA is combined with 3,5-diiodothyropropionic acid. (drugbank.ca)
  • These effects included hyperthermia, expression of uncoupling protein (UCP1 and 3) in brown adipose tissue or skeletal muscle and plasma free fatty acid (FFA) levels. (pubmedcentralcanada.ca)
  • 3] The most common side effects are cardiovascular, such as fast or irregular heartbeat, and psychological, such as anxiety. (pearltrees.com)
  • 4) "Controlled substance" means any substance named or described in Schedules I-V of s. 893.03. (flsenate.gov)
  • 3a) 'Commission' means the Commission for Mental Health, Developmental Disabilities, and Substance Abuse Services established under Part 4 of Article 3 of Chapter 143B of the General Statutes. (ncleg.net)
  • 4) 'Control' means to add, remove, or change the placement of a drug, substance, or immediate precursor included in Schedules I through VI of this Article. (ncleg.net)
  • 3. The physical appearance of the tablets, capsules or other finished product containing the substance is substantially identical to a specified controlled substance. (ncleg.net)
  • Schedule V and VI drug possession could result in a fine of $250 to $500 and are classified as either a Class 3 or Class 4 misdemeanor. (virginia-criminallawyer.com)
  • 3,4-Methylenedioxyamphetamine may increase the analgesic activities of Alfentanil. (drugbank.ca)
  • The method is based on direct ultraviolet detection of 5-amino-4-imidazolecarboxamide (AICA) and 5-amino-4-imidazolecarboxamide riboside (AICAr) in untreated urine. (chemweb.com)
  • For the four QNs, the detection limits at a signal-to-noise of 3 ranged from 0.36 to 2.4 ng/ml. (chemweb.com)
  • Total analysis time is 3 min with the limits of detection of 3.6 μM and 4.5 μM for AICA and AICAr, respectively. (chemweb.com)