3,3'-Dichlorobenzidine
International Agencies
Carcinogenicity Tests
Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.
Carcinogens
Compact Disks
3,3'-Dichlorobenzidine
Dichlorobenzidine - Compound Summary, PubChem. NIOSH Pocket Guide to Chemical Hazards. "#0191". National Institute for ... Dichlorobenzidine is an organic compound with the formula (C6H3Cl(NH2))2. The pure compound is pale yellow, but commercial ... Dichlorobenzidine is prepared in two steps from 2-nitrochlorobenzene. The first step involves reduction with zinc in base to ... Dichlorobenzidine is considered a carcinogen. This compound has been shown to increase the incidence of tumors in animals. ...
Pigment Yellow 12
... dichlorobenzidine. It is closely related to Pigment Yellow 13, wherein the two phenyl groups are replaced by 2,4-xylyl. K. ... It is also classified as a diarylide pigment, being derived from 3,3'- ...
Pigment Yellow 13
... dichlorobenzidine. It is closely related to Pigment Yellow 12, wherein the two xylyl groups are replaced by phenyl. K. Hunger. ... It is also classified as a diarylide pigment, being derived from 3,3'- ...
Pigment Yellow 81
... dichlorobenzidine. K. Hunger. W. Herbst "Pigments, Organic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, ... This compound is then coupled to the bisdiazonium salt obtained from 3,3'- ...
Mirosław Jan Stasik
... dichlorobenzidine and derivatives of aniline, as well as ethylene oxide and formaldehyde. In the 1980s Stasik represented ... His research was focused on defining the carcinogenic potential of some aromatic amines, e.g. 3,3'- ...
Diarylide pigment
... dichlorobenzidine, a carcinogen that is listed in the U.S. EPA's Toxics Release Inventory. 3,3'-Dichlorobenzidine is ... 3. Edited by A. T. Peters & H. S. Freeman, Blackie Academic & Professional, Glasgow, 1995, xii + 245 pp. ISBN 0 7514 0209 5. ... Rodenburg, L. A.; Guo, J.; Du, S.; Cavallo, G. J., Evidence for Unique and Ubiquitous Environmental Sources of 3,3'- ... Dyes and Pigments 2002, 55, (2-3), 79-89. Savastano, D., The pigment report: although 2006 was a year of improvement, pigment ...
Benzidine
Dichlorobenzidine o-tolidine, 3,3'-dimethyl-4,4'-benzidine o-dianisidine (3,3'-dimethoxy-4,4'-benzidine, CAS# 119-90-4, m.p. ... These derivatives include, in order of scale, the following: 3,3'- ... 133 °C) 3,3',4,4'-Tetraamino-diphenyl, precursor to polybenzimidazole fiber. As with some other aromatic amines such as 2- ...
List of MeSH codes (D02)
... dichlorobenzidine MeSH D02.455.426.559.389.185.475 - losartan MeSH D02.455.426.559.389.185.600 - niclofolan MeSH D02.455. ... 5-amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole MeSH D02.640.600.290 - fanft MeSH D02.640.600.308 - furagin MeSH D02.640. ... 3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide MeSH D02.092.146.325 - p-dimethylaminoazobenzene MeSH D02.092. ... vitamin k 3 MeSH D02.455.849.291.850 - taxoids MeSH D02.455.849.291.850.777 - paclitaxel MeSH D02.455.849.365 - dolichol MeSH ...
IARC group 2B
Dichlorobenzidine 3,3'-Dichloro-4,4'-diaminodiphenyl ether 1,2-Dichloroethane 1,3-Dichloropropene (technical grade) 1,3- ... A-α-C (2-Amino-9H-pyrido[2,3-b]indole) Acetaldehyde Acetamide Acrylonitrile AF-2 (2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide) ... 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole) Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole) Trypan blue Uracil mustard ... 3',2'-d]imidazole) Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) Glycidaldehyde Griseofulvin HC Blue No. 1 Heptachlor ...
3,3'-Dichlorobenzidine | ToxFAQs™ | ATSDR
... dichlorobenzidine may cause sore throat, respiratory infections, stomach upset, headache, dizziness, burns, and dermatitis. It ... Dichlorobenzidine sticks to soils or sediments and can travel in air or water for long distances if it is not exposed to ... dichlorobenzidine?. *You may be exposed to 3,3-dichlorobenzidine if you work in a facility that produces or uses it. ... dichlorobenzidine?. There are tests to check for exposure to 3,3-dichlorobenzidine using blood and urine that can be sent by ...
3,3'-Dichlorobenzidine
Dichlorobenzidine, 3,3'- (2005-110) | NIOSH | CDC
Dichlorobenzidine, 3,3′-. CAS No: 91-94-1. NOTE:. (1) Efficacy of Medical Tests has not been evaluated.. (2) NIOSH references ... Dichlorobenzidine, 3,3′-. Editor(s). /Author(s). Specific Medical Test(s) or Examination(s). Reference(s). ... 3) OSHA mandated medical tests, if any, are provided in BOLD on a yellow background.. (4) This HTML page was created from DHHS ...
3,3'-Dichlorobenzidine
Toxicological Profile for 33-Dichlorobenzidine | Peer Review Agenda | ATSDR
Dichlorobenzidine (DCBZ). Subject of Planned Report: The ATSDR toxicological profile succinctly reviews the toxicologic and ... 3. Kenneth Rosenman. 3. Deziel, Nicole. Academic and Professional Credentials. MD. Board Certified:. American Board of Internal ... Anticipated Number of Reviewers: 3. Primary Disciplines or Expertise: Exposure assessment, toxicology, environmental and/or ...
Details for: 3,3'-Dichlorobenzidine. › WHO HQ Library catalog
Substance Information - ECHA
... dichlorobenzidine dihydrochloride. Regulatory process names 8 CAS names 1 IUPAC names 8 Trade names 9 Other identifiers 1 ... 7 and points 2 and 3 of the Annex to Directive 94/33/EC, to which young persons (under 18 years of age) may not be exposed at ... 3(8), and Annexes I and III. The listed substances meet the European Unions definitions as hazardous, as provided on: (1) ... This list contains a non-exhaustive inventory of substances originating from: (1) Table 3 of Annex VI to CLP (i.e., the list of ...
NIOSHTIC-2 Search Results - Full View
Rule 3745-114-01 - Ohio Administrative Code | Ohio Laws
dichlorobenzidine, 3,3-. 00091-94-1. dichlorodiphenyl trichloroethane, p,p- (DDT). 00050-29-3. ... Amplifies: 3704.03(F)(3)(c), 3704.03(F)(4) Five Year Review Date: 5/8/2025 Prior Effective Dates: 12/1/2006 ... 13463-39-3. nickel, as Ni; elemental; soluble inorganic compounds; insoluble inorganic compounds (NOS); nickel subsulfide, as ...
Toxicological Profiles | ATSDR
NDEE Publications
This guidance document is advisory in nature but is binding on an agency until amended by such agency. A guidance document does not include internal procedural documents that only affect the internal operations of the agency and does not impose additional requirements or penalties on regulated parties or include confidential information or rules and regulations made in accordance with the Administrative Procedure Act. If you believe that this guidance document imposes additional requirements or penalties on regulated parties, you may request a review of the document. ...
IARC Publications Website - Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1-42
Dichlorobenzidine. * Dichloromethane [superseded by Volume 71]. * 1,3-Dichloropropene (technical-grade) [superseded by Volume ... 1,2-Dibromo-3-chloropropane [superseded by Volume 71]. * ortho-Dichlorobenzene and para-dichlorobenzene [superseded by Volume ... 2,3,7,8-Tetrachlorodibenzo-para-dioxin (TCDD) [superseded by Volume 69] ...
SYNTHETIC ORG. CHEM. MFRS | 506 F.2d 385 (1974) | 6f2d3851846 | Leagle.com
... dichlorobenzidine (DCB) by employers who utilize it are similar to those raised in connection with EI - that is, the data ... 3. no monitoring requirements were included in the final regulation; and. 4. no specific tests were set forth as part of the ... 3. MOCA is the trade name utilized by duPont, although the same chemical is used by other industrial chemical concerns. We use ... Paragraph (3) provides that, if objections are filed to the proposed rule and a hearing is requested, notice of the hearing ...
US Patent for Thermoplastic polyurethane compositions having improved flame resistance Patent (Patent # 4,690,964 issued...
... dichlorobenzidine, 3,3-dinitrobenzidine and the like, alkanol amines such as, for example, ethanol amine, aminopropyl alcohol ... b is 0 or an integer from 1 to 3 and. A can denote C.sub.1 -C.sub.8 alkylene, C.sub.2 -C.sub.8 alkylidene, C.sub.5 -C.sub.6 ... b is an integer of from 0 to 3 and A denotes a C.sub.1 -C.sub.8 alkylene, C.sub.2 -C.sub.8 alkylidene, C.sub.5 -C.sub.6 ... sup.(3) A propoxylated sucrose having an OH number of 370. .sup.(4) Cabo-sil is the trade name of a brand of fumed silica. ...
Results of search for 'ccl=su:{Environmental Exposure} and au:Meek, M. E.' › WHO HQ Library catalog
DeCS
Dichlorobenzidine - Preferred Concept UI. M0023227. Scope note. A material used in the manufacture of azo dyes that is toxic to ... 3,3-diclorobenzidina Scope note:. Material utilizado en la fabricación de colorantes azoicos. Es tóxico para la piel y ... 1,1-Biphenyl)-4,4-diamine, 3,3-dichloro- Previous Indexing:. Aniline Compounds (1969-1974). Benzidines/AA (1975-1976). ... We invite you to complete a survey that will take no more than 3 minutes.. Go to survey ...
Code System Concept
Toxicological Profiles | ATSDR
Renal-Urinary System
... dichlorobenzidine. Two other aromatic amines, 4,4´-methylene dianiline (MDA) and 4,4´-methylene-bis-2-chloroaniline (MOCA) are ... Figure 3. Four biomarkers, G-actin, P-300, DD23 and DNA, in relation to tumour progression and response to surgical treatment ... Markers such as the cancer gene on chromosome 3 observed in cancer families and in von Hippel-Lindau disease may serve as ... Toxicity to the P-3 segment results in the release into the urine of enzymes, such as intestinal alkaline phosphatase, N-acetyl ...
waterquality.lcra.org
Toxicological Profile for Chlorine | Peer Review Agenda | ATSDR
Pesquisa | Portal Regional da BVS
3. Urinary levels of 30 metal/metalloids in the Brazilian southeast population: Findings from the Brazilian Longitudinal Study ... Concentrations in clothing were also used to evaluate the dermal exposure to AAs in 3 vulnerable population groups. The highest ... Lipid species (164 in total) belonging to 3 different lipid categories, glycerophospholipids, sphingolipids, and glycerolipids ... 3,3-dichlorobenzidine was associated with potential cancer risks for newborns and toddlers in Brazil. Given this topics ...
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Overv iew of Preventable Industrial Causes of
Dichlorobenzidine (0) Dichloroethyl ether 1 ,3-Dichloropropene Dieldrin Diesel exhaust Diglycidyl ether (DGE); class, glycidyl ... 3. Silverman DT, Levin LI, Hoover RN, Hartge P. Occupational risks of bladder cancer in the United States. I: White men. J Natl ... 3). Volume 103, Supplement 8, November 1995 Adapted from Rinsky et al. (10). 199 E. WARD mineral oils, 2 million to lubricating ... A total of 10 to 20% of lung cancers (2) and 21 to 27% of bladder cancers (3,4) are estimated to be related to occupational ...
View - NSW legislation
3 Land vested in the Crown or an authority (within the meaning of the Public Finance and Audit Act 1983) that:. (a) is used or ... 3) Exception for owner Subsection (1) (a) does not apply if a person who was an owner of the land at the relevant time:. (a) ... 3) This section has effect subject to the Independent Pricing and Regulatory Tribunal Act 1992.. s 74: Am 2001 No 56, Sch 1.19 ... 3) A notice under this Act to a government department or administrative office may be served:. (a) in the case of a notice of ...
40 CFR 131.38 - Establishment of numeric criteria for priority toxic pollutants for the State of California.
Dichlorobenzidine. 91941. a c s 0.04. a c t 0.077 79. Diethyl Phthalate. 84662. a s 23,000. a t 120,000 80. Dimethyl Phthalate ... 3. Beryllium. 7440417. ( n). ( n) 4. Cadmium b. 7440439. e i m w x 4.3. e i m w 2.2. i m 42. i m 9.3. ( n). ( n) 5a. Chromium ( ... g, 3. g, 1.3. a c 0.00013. a c 0.00014 103. alpha-BHC. 319846. a c 0.0039. a c 0.013 104. beta-BHC. 319857. a c 0.014. a c ... Indeno(1,2,3-cd) Pyrene. 193395. a c 0.0044. a c 0.049 93. Isophorone. 78591. c s 8.4. c t 600 94. Naphthalene. 91203. 95. ...
919411
- Of about 30 workers in the Pigments Department, four were involved in handling 3,3'-dichlorobenzidine (91941) (DCB). (cdc.gov)
Bladder cancer1
- 3,3'-Dichlorobenzidine exposure has been associated with an increased risk of bladder cancer in workers who have used 3,3'-dichlorobenzidine in manufacturing for long periods of time. (cdc.gov)
19982
- 1998). 3,3'-Dichlorobenzidine. (who.int)
- Am 1998 No 145, Sch 3 [1]. (nsw.gov.au)
Pigments1
- 3,3'-Dichlorobenzidine is a man-made chemical used in the production of dyes and pigments that are in textiles, plastics, rubbers, and leather. (cdc.gov)
Dyes2
DHHS1
- The U.S. Department of Health and Human Services (DHHS) has classified 3,3'-dichlorobenzidine as reasonably anticipated to be a human carcinogen (substance causing cancer), based on evidence from animal studies. (cdc.gov)
Urine1
- There are tests to check for exposure to 3,3'-dichlorobenzidine using blood and urine that can be sent by your doctor to appropiate laboratories for analysis. (cdc.gov)
Benzidine1
- Its featured products include salicylic acid series, 3-3 dichloro-benzidine hydrochloride (DCB), phenethyl alcohol, furfuryl alcohol, dimethyl furan, PE pipes, caustic soda & solid caustic soda and polyether polyols. (sdlxgroup.com)
Occupational Exposure1
- A total of 10 to 20% of lung cancers (2) and 21 to 27% of bladder cancers (3,4) are estimated to be related to occupational exposure. (cdc.gov)
Developmental1
- There is not enough information to determine if 3,3'-dichlorobenzidine leads to developmental effects in these animals after birth. (cdc.gov)
Assessment1
- Several agencies and organizations both in the United States and internationally have reviewed studies and made an assessment about whether 3,3'-dichlorobenzidine could cause cancer. (cdc.gov)
Cancers1
- Studies in animals that ate this chemical have shown that 3,3'-dichlorobenzidine can increase the risk of tumors and other cancers, and may result in mild-to-moderate liver injury. (cdc.gov)
Tests3
- The tests may only tell you if you have been recently exposed to 3,3'-dichlorobenzidine and will not predict if you will have health problems. (cdc.gov)
- 3) OSHA mandated medical tests, if any, are provided in BOLD on a yellow background. (cdc.gov)
- The contentions made here with respect to 3,3'-dichlorobenzidine (DCB) by employers who utilize it are similar to those raised in connection with EI - that is, the data derived from tests revealing carcinogenicity in animals were not properly extrapolated to human susceptibility. (leagle.com)
Medical test1
- Can I get a medical test to check for 3,3'-dichlorobenzidine? (cdc.gov)
Material1
- Material utilizado en la fabricación de colorantes azoicos. (bvsalud.org)
Chemical1
- 3,3'-Dichlorobenzidine can be found in the environment near facilities making or using the chemical, or in hazardous waste sites through industrial wastewater discharge. (cdc.gov)
Indeno1
- Two other polycyclic (polynuclear) aromatic hydrocarbons also are resolved better using the 0.18 mm ID column, indeno(1,2,3-cd)pyrene and dibenzo(a,h)anthracene. (restek.com)
Lipids4
- Covalent interaction of 3,3'-dichlorobenzidine with hepatic lipids. (nih.gov)
- dichlorobenzidine to rats resulted in the in vivo covalent binding of the compound to hepatic lipids. (nih.gov)
- dichlorobenzidine-bound microsomal lipids were not mutagenic to Salmonella TA98 in the Ames test. (nih.gov)
- To analyze cellular internalization of liposomes, in aliquots of liposomal formulations, DOTAP was mixed with the fluorescent NBD-DOTAP (1-oleoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-3-trimethylammonium propane chloride salt, Avanti Polar Lipids) in a mole ratio of 100:1 DOTAP:NBD-DOTAP. (medscape.com)
Show1
- The 30 m x 0.25 mm x 0.25 df column (Figure 3) and the 20 m x 0.18 mm x 0.18 df column (Figure 4) both show high efficiency for PAHs. (restek.com)
Comments1
- Send an original and 3 copies of written comments to W-98-24 Comment Clerk, Water Docket, MC 4104, US EPA, 401 M Street, S.W., Washington, D.C. 20460. (epa.gov)
Environmental1
- ACGIH is a 501(c)(3) charitable scientific organization that advances occupational and environmental health. (acgih.org)