1-Naphthylamine
Naphthalenes
Organic Chemistry Phenomena
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Carcinogenicity Tests
Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.
Compact Disks
Fluorescence studies of the carboxyl-terminal domain of smooth muscle calponin effects of F-actin and salts. (1/241)
The fluorescence parameters of the environment-sensitive acrylodan, selectively attached to Cys273 in the C-terminal domain of smooth muscle calponin, were studied in the presence of F-actin and using varying salt concentrations. The formation of the F-actin acrylodan labeled calponin complex at 75 mm NaCl resulted in a 21-nm blue shift of the maximum emission wavelength from 496 nm to 474 nm and a twofold increase of the fluorescent quantum yield at 460 nm. These spectral changes were observed at the low ionic strengths (< 110 mm) where the calponin : F-actin stoichiometry is 1 : 1 as well as at the high ionic strengths (> 110 mm) where the binding stoichiometry is a 1 : 2 ratio of calponin : actin monomers. On the basis of previous three-dimensional reconstruction and chemical crosslinking of the F-actin-calponin complex, the actin effect is shown to derive from the low ionic strength interaction of calponin with the bottom of subdomain-1 of an upper actin monomer in F-actin and not from its further association with the subdomain-1 of the adjacent lower monomer which occurs at the high ionic strength. Remarkably, the F-actin-dependent fluorescence change of acrylodan is qualitatively but not quantitatively similar to that earlier reported for the complexes of calponin and Ca2+-calmodulin or Ca2+-caltropin. As the three calponin ligands bind to the same segment of the protein, encompassing residues 145-182, the acrylodan can be considered as a sensitive probe of the functioning of this critical region. A distance of 29 A was measured by fluorescence resonance energy transfer between Cys273 of calponin and Cys374 of actin in the 1 : 1 F-actin-calponin complex suggesting that the F-actin effect was allosteric reflecting a global conformational change in the C-terminal domain of calponin. (+info)Cysteine-scanning mutagenesis of an eukaryotic pore-forming toxin from sea anemone: topology in lipid membranes. (2/241)
Equinatoxin II is a cysteineless pore-forming protein from the sea anemone Actinia equina. It readily creates pores in membranes containing sphingomyelin. Its topology when bound in lipid membranes has been studied using cysteine-scanning mutagenesis. At approximately every tenth residue, a cysteine was introduced. Nineteen single cysteine mutants were produced in Escherichia coli and purified. The accessibility of the thiol groups in lipid-embedded cysteine mutants was studied by reaction with biotin maleimide. Most of the mutants were modified, except those with cysteines at positions 105 and 114. Mutants R144C and S160C were modified only at high concentrations of the probe. Similar results were obtained if membrane-bound biotinylated mutants were tested for avidin binding, but in this case three more mutants gave a negative result: S1C, S13C and K43C. Furthermore, mutants S1C, S13C, K20C, K43C and S95C reacted with biotin only after insertion into the lipid, suggesting that they were involved in major conformational changes occurring upon membrane binding. These results were further confirmed by labeling the mutants with acrylodan, a polarity-sensitive fluorescent probe. When labeled mutants were combined with vesicles, the following mutants exhibited blue-shifts, indicating the transfer of acrylodan into a hydrophobic environment: S13C, K20C, S105C, S114C, R120C, R144C and S160C. The overall results suggest that at least two regions are embedded within the lipid membrane: the N-terminal 13-20 region, probably forming an amphiphilic helix, and the tryptophan-rich 105-120 region. Arg144, Ser160 and residues nearby could be involved in making contacts with lipid headgroups. The association with the membrane appears to be unique and different from that of bacterial pore-forming proteins and therefore equinatoxin II may serve as a model for eukaryotic channel-forming toxins. (+info)ATP-induced opposite changes in the local environments around Cys(697) (SH2) and Cys(707) (SH1) of the myosin motor domain revealed by the prodan fluorescence. (3/241)
To obtain a consistent view of the nucleotide-induced conformational changes around Cys(697) (SH2) and Cys(707) (SH1) in skeletal myosin subfragment-1 (S-1), the two thiols were labeled with the same environmentally sensitive fluorophore, 6-acyl-2-dimethylaminonaphthalene group, using 6-acryloyl-2-dimethylaminonaphthalene (acrylodan, AD) and 6-bromoacetyl-2-dimethylaminonaphthalene (BD), respectively. The resultant fluorescent derivatives, AD-S-1 and BD-S-1, have the same fluorophore at either SH2 or SH1, which was verified by inspections of changes in the ATPases and the localization of fluorescence after tryptic digestion and CNBr cleavage for the two derivatives. Especially, AD was found to be a very useful fluorescent reagent that readily reacts with only SH2 of S-1. Measurements of the nucleotide-induced changes in fluorescence emission spectra of AD-S-1 and BD-S-1 suggested that during ATP hydrolysis the environment around the fluorophore at SH2 is very distinct from that around the fluorophore at SH1, being defined as that the former has the hydrophobic and closed characteristics, whereas the latter has the hydrophilic and open ones. The KI quenching study of the fluorescence of the two S-1 derivatives confirmed these results. The most straightforward interpretation for the present results is that during ATP hydrolysis, the helix containing SH2 is buried in hydrophobic side chains and rather reinforced, whereas the adjacent helix containing SH1 moves away from its stabilizing tertiary structural environment. (+info)Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles. (4/241)
Using the sectioning effect of the two-photon fluorescence microscope, we studied the behavior of phospholipid giant unilamellar vesicles (GUVs) composed of pure diacylphosphatidylcholine phospholipids during the gel-to-liquid crystalline phase transition. We used the well-characterized excitation generalized polarization function (GP(ex)) of 6-dodecanoyl-2-dimethylamine-naphthalene (LAURDAN), which is sensitive to the changes in water content in the lipid vesicles, to monitor the phase transition in the GUVs. Even though the vesicles do not show temperature hysteresis at the main phase transition, we observed different behaviors of the vesicle shape, depending on how the GUV sample reaches the main phase transition. During the cooling cycles, we observed an increase in the vesicle diameter at the phase transition ( approximately 0.5-1%), followed by a decrease in the diameter when the vesicle reached the gel phase. During the heating cycles and close to the phase transition temperature, a surprising behavior is observed, showing a sequence of different vesicle shapes as follows: spherical-polygonal-ellipsoidal. We attribute these changes to the effect of lipid domain coexistence on the macroscopic structure of the GUVs. The "shape hysteresis" in the GUVs is reversible and largely independent of the temperature scan rate. In the presence of 30 mol% of cholesterol the events observed at the phase transition in the GUVs formed by pure phospholipids were absent. (+info)Hydration of lipoplexes commonly used in gene delivery: follow-up by laurdan fluorescence changes and quantification by differential scanning calorimetry. (5/241)
Lipoplexes, which are formed spontaneously between cationic liposomes and negatively charged nucleic acids, are commonly used for gene and oligonucleotide delivery in vitro and in vivo. Being assemblies, lipoplexes can be characterized by various physicochemical parameters, including size distribution, shape, physical state (lamellar, hexagonal type II and/or other phases), sign and magnitude of electrical surface potential, and level of hydration at the lipid-DNA interface. Only after all these variables will be characterized for lipoplexes with a broad spectrum of lipid compositions and DNA/cationic lipid (L(+)) mole (or charge) ratios can their relevance to transfection efficiency be understood. Of all these physicochemical parameters, hydration is the most neglected, and therefore the focus of this study. Cationic liposomes composed of DOTAP without and with helper lipids (DOPC, DOPE, or cholesterol) or of DC-Chol/DOPE were complexed with pDNA (S16 human growth hormone) at various DNA(-)/L(+) charge ratios (0.1-3.2). (DOTAP=N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium chloride; DC-Chol=(3beta-[N-(N',N'-dimethylaminoethane)-carbamoyl]-cholester ol; DOPC=1, 2-dioleoyl-sn-glycero-3-phosphocholine; DOPE=1, 2-dioleoyl-sn-glycero-3-phosphoethanolamine). The hydration levels of the different cationic liposomes and the DNA separately are compared with the hydration levels of the lipoplexes. Two independent approaches were applied to study hydration. First, we used a semi-quantitative approach of determining changes in the 'generalized polarization' (GP) of laurdan (6-dodecanoyl-2-dimethylaminonaphthalene). This method was recently used extensively and successfully to characterize changes of hydration at lipid-water interfaces. Laurdan excitation GP at 340 nm (GP(340)DOTAP. The GP(340) of lipoplexes of all lipid compositions (except those based on DC-Chol/DOPE) was higher than the GP(340) of the cationic liposomes alone and increased with increasing DNA(-)/L(+) charge ratio, reaching a plateau at a charge ratio of 1. 0, suggesting an increase in dehydration at the lipid-water interface with increasing DNA(-)/L(+) charge ratio. Confirmation was obtained from the second method, differential scanning calorimetry (DSC). DOTAP/DOPE lipoplexes with charge ratio 0.44 had 16.5% dehydration and with charge ratio 1.5, 46.4% dehydration. For DOTAP/Chol lipoplexes with these charge ratios, there was 17.9% and 49% dehydration, respectively. These data are in good agreement with the laurdan data described above. They suggest that the dehydration occurs during lipoplex formation and that this is a prerequisite for the intimate contact between cationic lipids and DNA. (+info)Electrostatic properties of membranes containing acidic lipids and adsorbed basic peptides: theory and experiment. (6/241)
The interaction of heptalysine with vesicles formed from mixtures of the acidic lipid phosphatidylserine (PS) and the zwitterionic lipid phosphatidylcholine (PC) was examined experimentally and theoretically. Three types of experiments showed that smeared charge theories (e.g., Gouy-Chapman-Stern) underestimate the membrane association when the peptide concentration is high. First, the zeta potential of PC/PS vesicles in 100 mM KCl solution increased more rapidly with heptalysine concentration (14.5 mV per decade) than predicted by a smeared charge theory (6.0 mV per decade). Second, changing the net surface charge density of vesicles by the same amount in two distinct ways produced dramatically different effects: the molar partition coefficient decreased 1000-fold when the mole percentage of PS was decreased from 17% to 4%, but decreased only 10-fold when the peptide concentration was increased to 1 microM. Third, high concentrations of basic peptides reversed the charge on PS and PC/PS vesicles. Calculations based on finite difference solutions to the Poisson-Boltzmann equation applied to atomic models of heptalysine and PC/PS membranes provide a molecular explanation for the observations: a peptide adsorbing to the membrane in the presence of other surface-adsorbed peptides senses a local potential more negative than the average potential. The biological implications of these "discreteness-of-charge" effects are discussed. (+info)Two photon fluorescence microscopy of coexisting lipid domains in giant unilamellar vesicles of binary phospholipid mixtures. (7/241)
Images of giant unilamellar vesicles (GUVs) formed by different phospholipid mixtures (1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1, 2-dilauroyl-sn-glycero-3-phosphocholine (DPPC/DLPC) 1:1 (mol/mol), and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine/1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPE/DPPC), 7:3 and 3:7 (mol/mol) at different temperatures were obtained by exploiting the sectioning capability of a two-photon excitation fluorescence microscope. 6-Dodecanoyl-2-dimethylamino-naphthalene (LAURDAN), 6-propionyl-2-dimethylamino-naphthalene (PRODAN), and Lissamine rhodamine B 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine (N-Rh-DPPE) were used as fluorescent probes to reveal domain coexistence in the GUVs. We report the first characterization of the morphology of lipid domains in unsupported lipid bilayers. From the LAURDAN intensity images the excitation generalized polarization function (GP) was calculated at different temperatures to characterize the phase state of the lipid domain. On the basis of the phase diagram of each lipid mixture, we found a homogeneous fluorescence distribution in the GUV images at temperatures corresponding to the fluid region in all lipid mixtures. At temperatures corresponding to the phase coexistence region we observed lipid domains of different sizes and shapes, depending on the lipid sample composition. In the case of GUVs formed by DPPE/DPPC mixture, the gel DPPE domains present different shapes, such as hexagonal, rhombic, six-cornered star, dumbbell, or dendritic. At the phase coexistence region, the gel DPPE domains are moving and growing as the temperature decreases. Separated domains remain in the GUVs at temperatures corresponding to the solid region, showing solid-solid immiscibility. A different morphology was found in GUVs composed of DLPC/DPPC 1:1 (mol/mol) mixtures. At temperatures corresponding to the phase coexistence, we observed the gel domains as line defects in the GUV surface. These lines move and become thicker as the temperature decreases. As judged by the LAURDAN GP histogram, we concluded that the lipid phase characteristics at the phase coexistence region are different between the DPPE/DPPC and DLPC/DPPC mixtures. In the DPPE/DPPC mixture the coexistence is between pure gel and pure liquid domains, while in the DLPC/DPPC 1:1 (mol/mol) mixture we observed a strong influence of one phase on the other. In all cases the domains span the inner and outer leaflets of the membrane, suggesting a strong coupling between the inner and outer monolayers of the lipid membrane. This observation is also novel for unsupported lipid bilayers. (+info)A further cohort study of workers employed at a factory manufacturing chemicals for the rubber industry, with special reference to the chemicals 2-mercaptobenzothiazole (MBT), aniline, phenyl-beta-naphthylamine and o-toluidine. (8/241)
OBJECTIVES: To investigate mortality and cancer morbidity in workers from a factory manufacturing chemicals for the rubber industry. METHODS: The mortality (1955-96) and cancer morbidity experience (1971-92) of a cohort of 2160 male production workers from a chemical factory in north Wales were investigated. All subjects had at least 6 months employment at the factory and some employment in the period 1955-84. Detailed job histories were abstracted from company computerised records and estimates of individual cumulative exposure to 2-mercaptobenzothiazole (MBT) and its derivatives were obtained, with a job exposure matrix derived by a former factory hygienist. Durations of employment in the aniline, phenyl-beta-naphthylamine (PBN) and o-toluidine departments were also calculated. Two analytical approaches were used, indirect standardisation and Poisson regression. RESULTS: Based on serial rates for the general population of England and Wales, observed mortality for the total cohort was close to expectation for all causes (observed (obs) deaths 1131, expected (exp) deaths 1114.5, standardised mortality ratio (SMR) 101), and for all cancers (obs 305, exp 300.2, SMR 102). There was a significant (p < 0.05) excess mortality from cancer of the bladder in the 605 study subjects potentially exposed to one or more of the four chemicals being investigated (obs 9, exp 3.25, SMR 277, 95% confidence interval (95% CI) 127 to 526). This excess was dependent primarily on deaths occurring > 20 years after first exposure in those who started employment before 1955 (obs 7, exp 1.25, SMR 560, 95% CI 225 to 1154, p < 0.001). There were 30 subjects in the total study cohort who, on the basis of death certificates or cancer registration particulars, had had malignant bladder cancer. In separate analyses of the four exposure history variables (after adjustment for age), Poisson regression showed significant positive trends for risk of notification of bladder cancer increasing with cumulative duration of employment in the PBN (p < 0.001) and o-toluidine departments (p < 0.01); similar findings were not obtained for cumulative exposure to MBT or for duration of employment in the aniline department. In a simultaneous analysis of all four chemical exposure variables, a significant positive trend remained for duration of employment with exposure to PBN (p < 0.05). Further analyses of all cases of bladder cancer (malignant and benign diagnoses) used employment histories lagged by 15 years; similar findings were obtained. CONCLUSIONS: It seems likely that some members of this cohort have had occupational bladder cancer. Confident interpretation is difficult because of small numbers in the exposed subcohorts, relatively crude measures of exposure assessment for the four chemicals under study, and presence of unconsidered potential chemical confounders. The simplest interpretation of the findings about bladder cancer may be that PBN (or a chemical reagent or chemical intermediate associated with its production at this factory in the 1930s and 1940s) is a bladder carcinogen. Priority should be given, however, to obtaining information on the cancer experience of other working populations exposed to PBN or to o-toluidine. (+info)Phase-fluorometry study on dielectric relaxation of acrylodan-labeled human serum albumin<...
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2-Naphthylamine
Naphthalene Naphthol 1-Naphthylamine 1,8-Bis(dimethylamino)naphthalene NIOSH Pocket Guide to Chemical Hazards. "#0442". ... When reduced by sodium in boiling amyl alcohol solution, it forms tetrahydro-3-naphthylamine, which exhibits the properties of ... 2-Naphthylamine was previously used as a dye precursor and rubber antioxidant in the 1930s, 40s and 50s. Dupont stopped using ... 2-Naphthylamine is found in cigarette smoke and suspected to contribute to the development of bladder cancer. It is activated ...
Bladder cancer
86 (2): 289-94. doi:10.1002/(sici)1097-0215(20000415)86:2. 3.0.co;2-m. PMID 10738259. Yan H, Ying Y, Xie H, Li J, Wang X, He L ... 3 (2): e26. doi:10.14440/bladder.2016.89. PMC 5336315. PMID 28261632. Zhang L, Wu B, Zha Z, Qu W, Zhao H, Yuan J (July 2019). " ... 105 (2): 123-38. doi:10.1016/0304-3835(96)04284-x. PMID 8697435. Chaudhary KS, Lu QL, Abel PD, Khandan-Nia N, Shoma AM, el Baz ... 3.0.CO;2-Q. PMID 10931463. van Osch FH, Jochems SH, van Schooten FJ, Bryan RT, Zeegers MP (June 2016). "Quantified relations ...
Prodan (dye)
"N,N-Dimethyl-6-propionyl-2-naphthylamine". Merck. Sigma-Aldrich. Retrieved 22 October 2019. Safety Data Sheet. Life ... 6-Propionyl-2-Dimethylaminonaphthalene)". Thermo Fisher Scientific. Retrieved 22 October 2019. "Prodan". PubChem. National ...
Aptiganel
1-Naphthylamine is reacted with cyanogen bromide to give 2. Treatment of this intermediate with 3-ethyl-N-methylaniline leads ... 37 (2): 260-7. doi:10.1021/jm00028a009. PMID 8295213. Muir KW, Grosset DG, Gamzu E, Lees KR (July 1994). "Pharmacological ... 37 (2): 260-7. doi:10.1021/jm00028a009. PMID 8295213. WO 9112797, Weber, Eckard & Keana, John F. W., "Tri- and tetra- ... 4 (2): 131-6. doi:10.2174/1566524043479248. PMID 15032709. Staff, Boston Business Journal. May 7, 1998. CNSI appoints new ...
Naphthylamine
... can refer to either of two isomeric chemical compounds: 1-Naphthylamine 2-Naphthylamine This set index page lists ...
NOBIN
Naphthylamines). ... NOBIN is prepared by oxidative cross coupling of 2-naphthol and ... NOBIN (2-amino-2'-hydroxy-1,1'-binaphthyl) is an organic molecule used for asymmetric catalysis. NOBIN is related to BINOL and ... 2;499-545 (Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, Chemical articles ... 2-naphthylamine. The oxidative source is metal ions in solution such as Fe2+ or a Cu2+ amine complex. Once racemic NOBIN is ...
N-(1-Naphthyl)ethylenediamine
However, it is a weaker bidentate ligand as the nitrogen atom in the naphthylamine group is weakly coordinating due to the ... This compound can be prepared by the reaction of 1-naphthylamine with 2-chloroethanamine. It is commercially available as the ... N-(1-Naphthyl)ethylenediamine undergoes most reactions typical to naphthylamine and primary amines such as diazotation. Similar ...
2-Amino-1,2-dihydronaphthalene
2-Amino-1,2-dihydronapthalene (2-ADN), also known as 2-aminodilin (2-AD), is a stimulant drug. It is a rigid analogue of ... 2-Aminoindane 2-Aminotetralin 2-Naphthylamine Hathaway BA, Nichols DE, Nichols MB, Yim GK (May 1982). "A new, potent, ... It is closely related to 2-aminotetralin (2-amino-1,2,3,4-tetrahydronaphthalene), which also substitutes for amphetamine, and ... 2-dihydronaphthalene". Journal of Medicinal Chemistry. 25 (5): 535-8. doi:10.1021/jm00347a011. PMID 6123601. (Articles with ...
Otto Michael Ludwig Leichtenstern
2-NA) was involved in human bladder tumorigenesis. With Adolph Strümpell (1853-1925), the eponymous "Strümpell-Leichtenstern ... In 1898 he suspected that the compound 2-naphthylamine ( ...
Pyrrolidonyl-β-naphthylamide
Naphthylamines, All stub articles, Heterocyclic compound stubs). ... it is broken down to pyroglutamic acid and 2-naphthylamine. To ...
Solvent Black 3
Sudan Black is formed by coupling of diazotized 4-phenylazo-1-naphthylamine with 2,3-dihydro-2,2-dimethyl-1H-perimidine. ... Therefore, the main product expected was 2,3-dihydro-2,2dimethyl-6-[(4-phenylazo-1-naphthalenyl)-azo]-1H-perimidine. However ... 3-dihydro-2,2-dimethyl-4-[(4-phenylazo-1-naphthalenyl)-azo]-1H-perimidine. Hunger, Klaus; Mischke, Peter; Rieper, Wolfgang; et ...
Orange B
... specifically 2-naphthylamine). The only supplier in the United States, the William J. Stange Company, subsequently stopped ...
Chlornaphazine
Naphthylamines, Nitrogen mustards, Chloroethyl compounds, Withdrawn drugs, 2-Naphthyl compounds). ... N,N-Bis(2-Chloroethyl)-2-Naphthylamine (Chlornaphazine), International Agency for Research on Cancer (ECHA InfoCard ID from ... Chlornaphazine, a derivative of 2-naphthylamine, is a nitrogen mustard that was developed in the 1950s for the treatment of ... Videbaek, A.; Kaae, S. (1954). "2-Naphthylbis(chloroethyl)amine in the treatment of malignant diseases, particularly Hodgkin's ...
3-Dimethylaminoacrolein
The amidine formed with 2-naphthylamine and the dimethyl sulfate adduct can be cyclized with sodium methoxide to give benzo[f] ... The use of 3-dimethylaminoacrolein for the synthesis of 2-chloronicotinic acid (2-CNA) is of industrial interest as an ... The resulting esters of 2-chloropyridine carboxylic acid can be hydrolyzed smoothly to 2-chloronicotinic acid. It reacts weakly ... 496-504, doi:10.1002/ange.19760881503 S. Makhseed; H.M.E. Hassaneen; M.H. Elnagdi (2007), "Studies with 2-(Arylhydrazono) ...
Kenneth Koe
4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotonin". The Journal of Pharmacology and ... Grohol, John M.; Founder, Psy D.; read, Editor-in-Chief Last updated: 8 Jul 2018 ~ 2 min (2017-10-12). "Top 25 Psychiatric ... Koe, BK (September 1983). "Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3, ...
Tametraline
4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotonin". The Journal of Pharmacology and ... 2.2.2]octane) JNJ-7925476 Lometraline Nefopam Sertraline Koe BK, Weissman A, Welch WM, Browne RG (September 1983). "Sertraline ...
Development and discovery of SSRI drugs
4-Tetrahydro-1-Naphthylamine, a New Uptake Inhibitor with Selectivity for Serotonin" (PDF). The Journal of Pharmacology and ... 41 (2): 58-85. PMID 18668017. (CS1 maint: multiple names: authors list, Wikipedia neutral point of view disputes from June 2016 ... Table 2 Comparison of the chemical properties of SSRI drugs Compounds containing an aryloxypropylamine motif in their structure ... 454 (2-3): 183-188. doi:10.1016/s0014-2999(02)02557-8. PMID 12421645. Koe, B. Kenneth; Weissman, Albert; Welch, Willard M.; ...
Benzidine
ISBN 0-471-60180-2. Shine, H. J.; Zmuda, H.; Park, K. H.; Kwart, H.; Horgan, A. G.; Collins, C.; Maxwell, B. E. (1981). " ... As with some other aromatic amines such as 2-naphthylamine, benzidine has been significantly withdrawn from use in most ... First, the nitrobenzene is converted to 1,2-diphenylhydrazine, usually using iron powder as the reducing agent. Treatment of ... 2. It is an aromatic amine. It is a component of a test for cyanide. Related derivatives are used in the production of dyes. ...
C10H9N
... or 4-methylquinoline 1-Naphthylamine 2-Naphthylamine Quinaldine This set index page lists chemical structure articles ...
Arylamine N-acetyltransferase
Other names in common use include arylamine acetylase, beta-naphthylamine N-acetyltransferase, 4-aminobiphenyl N- ... 2-naphthylamine N-acetyltransferase, arylamine acetyltransferase, indoleamine N-acetyltransferase, N-acetyltransferase, p- ...
IARC group 1
November 2, 2009 ‐‐ IARC has updated the cancer assessments of several personal habits and household exposures that cause ... 4-diium-2-yl)methylideneamino]carbamate) - GHS Category 1B Carcinogen Chlornapazine (N,N-Bis(2-chloroethyl)-2-naphthylamine) ... 2-Naphthylamine Nickel compounds 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) N-Nitrosonornicotine (NNN) 2,3,4,7,8- ... 2-chloroaniline) (MOCA) MOPP and other combined chemotherapy including alkylating agents Mustard gas (Sulfur mustard) ...
Control of Substances Hazardous to Health Regulations 2002
Supply is prohibited, during the course of work or for use at work, of (reg.4(3), (4)/ Sch.2, item.11): Any of the substances ... Regulation 9(2) [Various authors] (2007). Tolley's Health and Safety at Work Handbook 2008. London: Butterworths. ISBN 978-0- ... Use of the following substances is prohibited for the purposes specified (reg.4(1)/ Sch.2): The following are excluded from the ... The assessment must include consideration of any information provided by the supplier of a substance (CHIPS) (reg.6(2)(b)) and ...
Nile blue
This might take only 1-2 minutes. Then the sample is thoroughly rinsed in water (for one to two hours). Afterwards, the stained ... 3.0.CO;2-N. (Webarchive template wayback links, Chemical articles with multiple compound IDs, Chemicals using indexlabels, ... Alternatively, the product of an acid-catalyzed condensation of 4-nitroso-N,N-dialkylaniline with 2-naphthol (a salt of 9-( ... 2.0.CO;2. PMID 11202363. S2CID 198157623. Kanitz, Andreas; Hartmann, Horst (1999). "Preparation and Characterization of Bridged ...
Pyroglutamyl-peptidase I
791 (2): 117-122. doi:10.1016/0167-4838(84)90001-3. Awadé AC, Cleuziat P, Gonzalès T, Robert-Baudouy J (September 1994). " ... amino acid generally not being Pro PGPEP1 Pyrrolidonyl-beta-naphthylamide P-Dimethylaminocinnamaldehyde Pyroglutamic acid 2- ... Naphthylamine Panosian KJ, Edberg SC (March 1989). "Measurement of constitutive L-pyrrolidonyl peptidase activity from ...
List of MeSH codes (D04)
1-naphthylamine MeSH D04.615.638.845.800 - sertraline MeSH D04.615.638.850 - 2-naphthylamine MeSH D04.615.638.870 - 1- ... 25-hydroxyvitamin d 2 MeSH D04.808.247.808.489 - fusidic acid MeSH D04.808.247.808.607 - lanosterol MeSH D04.808.247.808.756 - ... 8-hydroxy-2-(di-n-propylamino)tetralin MeSH D04.615.638.960.492 - levobunolol MeSH D04.615.638.960.585 - mibefradil MeSH ... 25-hydroxyvitamin d 2 MeSH D04.808.247.222.537 - ergosterol MeSH D04.808.247.222.857 - sitosterols MeSH D04.808.247.808 - ...
Robert A. Kehoe
2, Winter 1999, at 95. Loeb (1999) Peterson, M (2007). "The precautionary principle should not be used as a basis for decision- ... Retrieved April 2, 2020. The smelter building for the most part could only be described as incredibly dirty, poorly ventilated ... 78 (2): 71-8. doi:10.1006/enrs.1997.3808. PMID 9719610. Jamie Lincoln Kitman (2000-03-20). "The Secret History of Lead". The ... 78 (2): 79-85. doi:10.1006/enrs.1997.3807. PMID 9719611. Kehoe RA (1953). "Experimental Studies on the Inhalation of Lead by ...
2-Methylnaphthalene-1,4-diamine
Naphthylamines, Vitamin K, Substances discovered in the 1920s). ... Veselý V, Kapp J (1925). "Sur les dérivés nitres du méthyl-2- ... 2-Methylnaphthalene-1,4-diamine was first synthetized in 1925. In 1942 two different research groups noted the vitamin K ... 11 (2): 175-183. doi:10.1023/A:1011237019082. ISSN 1573-742X. PMID 11406734. S2CID 975055. v t e (Articles without InChI source ... 2-Methylnaphthalene-1,4-diamine and its dihydrochloride can be made from 2-methylnaphthalene or its close analogs. ...
IARC group 3
... pyrene 1-Naphthylamine 1-Naphthylthiourea (ANTU) Nithiazide 5-Nitro-ortho-anisidine 9-Nitroanthracene 7-Nitrobenz[a]anthracene ... 2 HC Red No. 3 HC Yellow No. 4 Hepatitis D virus Hexachlorobutadiene Hexachlorophene Human T-cell lymphotropic virus type II ... 9 Dapsone Decabromodiphenyl oxide Deltamethrin Diacetylaminoazotoluene Diallate 1,2-Diamino-4-nitrobenzene 1,4-Diamino-2- ... nitrobenzene 2,5-Diaminotoluene Diazepam Diazomethane Dibenz[a,c]anthracene Dibenz[a,j]anthracene Dibenzo-p-dioxin Dibenzo[a,e] ...
Bucherer reaction
The Bucherer reaction in organic chemistry is the reversible conversion of a naphthol to a naphthylamine in the presence of ... The enamine eliminates sodium bisulfite with formation of naphthylamine 6. It is important to stress that this is a reversible ... C10H7-2-OH + NH3 ⇌ C10H7-2-NH2 + H2O The French chemist Robert Lepetit was the first to discover the reaction in 1898. The ... It is also useful for transamination reactions of 2-aminonaphthalenes. In the first step of the reaction mechanism a proton ...
Griess test
This diamine is used in place of the simpler and cheaper 1-naphthylamine because the latter is a potent carcinogen and moreover ... The detection limit of the Griess test generally ranges between 0.02 and 2 μM, depending on the exact details of the specific ...
Ivan Ostromislensky
He also proposed organic additions to rubber, such as toluidine and naphthylamine, in order to improve its properties. Those ... 2 H2O This process was used in the United States to produce government rubber during World War II, and remains in use today in ...
Evans blue (dye)
Naphthylamines). ...
Induline
... rosinduline from benzene-azo-α-naphthylamine and aniline and naphthinduline from benzene-azo-α-naphthylamine and naphthylamine ... Isorosinduline is obtained from quinone dichlorimide and phenyl-β-naphthylamine; ... The indulines may be subdivided into the following groups: (1) benzindulines, derivatives of phenazine; (2) isorosindulines; ...
Congo red
Naphthylamines, Biphenyls, Organic sodium salts). ...
Textile industry in Bangladesh
... regarding exposure to textile dyes and occupational bladder cancer due to aniline dye intermediates such as beta-naphthylamine ... 35 (1-2): 45-51. PMID 18516877. Metgud, D C; Khatri, S; Mokashi, M G; Saha, P N (2008). "An ergonomic study of women workers in ... Latifee, Enamul Hafiz (2 February 2016). "RMG sector towards a thriving future". The Daily Star. Paul, Ruma; Quadir, Serajul (4 ... 12 (2). Uddin, Anam. "Garment Industry in Bangladesh: An Era of Globalization and Neo-Liberalization". Middle East Journal of ...
List of designer drugs
November 2014). "Identification of N,N-bis(1-pentylindol-3-yl-carboxy)naphthylamine (BiPICANA) found in an herbal blend product ... 2C-B, "Siberia" 2C-B-AN, Brolphetaminil 2C-B-FLY 2C-C 2C-D, 2C-M 2C-E, "Europa" 2C-G 2C-iP, "Jelena" 2C-I 2C-P 2C-T-2 2C-T-4 2C ... "1-(2,3-Dihydro-1H-inden-5-yl)-2-(ethylamino)pentan-1-one". pubchem.ncbi.nlm.nih.gov. Gaspar H, Bronze S, Ciríaco S, Queirós CR ... "1-(2,3-Dihydro-1H-inden-5-yl)-2-pyrrolidin-1-ylbutan-1-one". pubchem.ncbi.nlm.nih.gov. "α-PBT". Cayman Chemical. Retrieved 27 ...
ACNA (company)
... notably including fabric dyes such as indigo and naphthylamine. It was discovered that the long standing deterioration of the ... 1 (2): 279-314. doi:10.1093/es/1.2.279. ISSN 1467-2227. JSTOR 23699775. Capanna, Saverio (2015). "L'ACNA di Cengio nel contesto ...
Amine
Anilines and naphthylamines form more stable diazonium salts, which can be isolated in the crystalline form. Diazonium salts ... RNH 2 + R 2 ′ C = O ⟶ R 2 ′ C = NR + H 2 O {\displaystyle {\ce {RNH2 + R'_2C=O -> R'_2C=NR + H2O}}} Reduction of these imines ... H − N , R 2 R 1 , : ⏟ amine + R 3 − C O ‖ − OH ⏟ carboxylic acid − > H − N + , R 2 R 1 , − H + R 3 − COO − ⏟ substituted- ... Secondary (2°) amines-Secondary amines have two organic substituents (alkyl, aryl or both) bound to the nitrogen together with ...
FDU-NNE1
... it is suspected that metabolic hydrolysis of the amide group of FDU-NNE1 will release 1-naphthylamine, a known carcinogen. 5F- ... 33 (2): 244-259. doi:10.1007/s11419-015-0268-7. PMC 4525202. PMID 26257833. v t e (Articles with short description, Short ...
Bechamp reduction
The reaction was first used by Antoine Béchamp to reduce nitronaphthalene and nitrobenzene to naphthylamine and aniline, ... Organic Reactions 2, 428 (1944) .Kahl, Thomas; Schröder, Kai-Wilfrid; Lawrence, F. R.; Marshall, W. J.; Höke, Hartmut; Jäckh, ... Mendenhall, P. M. G.; Smith, Peter A. S. (1966). "2-Nitrocarbazole". Org. Synth. 46: 85. doi:10.15227/orgsyn.046.0085. M. J. ... Mahood, S. A.; Schaffner, P. V. L. (1931). "2,4-Diaminotoluene". Org. Synth. 11: 32. doi:10.15227/orgsyn.011.0032. (Name ...
Mahmoud K. Muftić
Nature 201:622-623 Muftic MK (1964). N-acetyl-naphthylamine esterase activity as a virulence test in Mycobacteria. Zentralbl ... The Laryngoscope Volume 68, Issue 2, pp. 131-132. Muftic MK (1958). Advances in the pharmacological study of cerase-A new anti- ... British Journal of Diseases of the Chest, Volume 58, Issue 2, pp. 85-89. DOI: 10.1016/S0007-0971(64)80037-1. Muftić, M. (1964 ... Nigerian Journal of Islam, 1:2 (1971), pp. 23-28. Patents Kutzsche A, Muftic MK, Peissker H (1969). 3-methyl-5-isopropylphenyl ...
Laurdan
Naphthylamines, Tertiary amines). ... Because of a partial charge separation between the 2- ... Laurdan was first applied to study membrane fluidity of live cells with a 2-Photon fluorescence microscope in 1994 and it was ... 111 (2): 254-60. doi:10.1017/S0007114513002444. PMC 4327854. PMID 23962659. Wesołowska, O; Gąsiorowska, J.; Petrus, J.; Czarnik ... Weber, G.; F. J. Farris (1979). "Synthesis and spectral properties of a hydrophobic fluorescent probe: 6 propionyl-2-( ...
NNE1
It is suspected that metabolic hydrolysis of the amide group of NNE1 may release 1-naphthylamine, a known carcinogen, given the ... 365 (2): 437-446. doi:10.1124/jpet.117.246983. PMC 5932312. PMID 29549157. Blaazer AR, Lange JH, van der Neut MA, Mulder A, den ...
Malayan Emergency
N-Dimethyl-1-naphthylamine onto crops such as sweet potatoes and maize. Many Commonwealth personnel who handled and/or used ... The 2,4,5-T and 2,4-D (Agent Orange) were used to clear lines of communication and wipe out food crops as part of this strategy ... 9 (2): 286-305. doi:10.1017/s0217781100004713. Thousands of Orang Asli were escorted out of the jungle by the police and the ... 2 Squadron (replacing No. 1 Squadron) and CAC Sabres of No. 78 Wing carried out ground attack missions against the guerrillas. ...
Bechamp reaction
The Application of the Béchamp Reaction to α-Naphthylamine". J. Am. Chem. Soc. 56: 151. doi:10.1021/ja01316a047.. Grund, Sabina ... 2. doi:10.1002/0471264180.or002.10. ISBN 0471264180. P. Ehrlich & A. Bertheim (1907). "Überp-Aminophenylarsinsäure". Chemische ...
RTECS:QM2100000 - 2-Naphthylamine - The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH
beta-Naphthylamine. beta-Naphthylamine (ACGIH:OSHA). C.I. 37270. Fast Scarlet Base B. RCRA waste number U168. USAF CB-22. ... 6-Naphthylamine. beta-Naftalamin (Czech). beta-Naftilamina (Italian). beta-Naftylamin (Czech). beta-Naftyloamina (Polish). beta ... National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO beta-NAPHTHYLAMINE-air. Carcinogen ... 2 µg/plate (-enzymatic activation step). BECTA6 17,739,1977. mutation in microorganisms. /Bacillus subtilis. 5 gm/L (+enzymatic ...
Amine-function compounds; aromatic monoamines and their derivatives; 1-naphthylamine (alpha-naphthylamine), 2-naphthylamine ...
HS Code 292145: Amine-function compounds; aromatic monoamines and their derivatives; 1-naphthylamine (alpha-naphthylamine), 2- ... Amine-function compounds; aromatic monoamines and their derivatives; 1-naphthylamine (alpha-naphthylamine), 2-naphthylamine ( ... Amine-function compounds; aromatic monoamines and their derivatives; 1-naphthylamine (alpha-naphthylamine), 2-naphthylamine ( ... Amine-function compounds; aromatic monoamines and their derivatives; 1-naphthylamine (alpha-naphthylamine), 2-naphthylamine ( ...
N-Phenyl-1-naphthylamine | 90-30-2 suppliers - BuyersGuideChem
Get supplier listing of N-Phenyl-1-naphthylamine and equal product ... N-Phenyl-alpha-naphthylamine. Supplier of. N-Phenyl-alpha-naphthylamine. (CAS: 90-30-2) ... Merck Schuchardt OHG is supplier for N-Phenyl-1-naphthylamine. Country: Germany Phone: +49-8102-802 0 Telefax: +49-8102-802 175 ... is supplier for N-Phenyl-1-naphthylamine. In our R&D centre, we have a staff of skilled and experienced research chemists. This ...
CAS 90-30-2 | Phenyl Alpha Naphthylamine :: 주식회사 오티스 OTS
CypComp Database: Showing CypComp Card for CC01806: 2-Naphthylamine (CypBoM Training Set)
Butler MA, Iwasaki M, Guengerich FP, Kadlubar FF: Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proc Natl Acad Sci U S A. 1989 Oct;86(20):7696-700. doi: 10.1073/pnas.86.20.7696. [PubMed:2813353 ...
Substance Information - ECHA
Buy N-Acetyl-2-naphthylamine online-CAS 581-9-7--5,N-Acetyl-2-naphthylamine Prices from Green Stone
N-Acetyl-2-naphthylamine Suppliers,N-Acetyl-2-naphthylamine Manufacturers,N-Acetyl-2-naphthylamine Exporters on GREEN STONE - ... About N-Acetyl-2-naphthylamine prices,N-Acetyl-2-naphthylamine sales.Ciontact us,Email:[email protected] ...
NIOSHTIC-2 Search Results - Full View
In the British rubber industry, the use of b-naphthylamine ended in 1949 and was mainly replaced by N-phenyl- 2-naphthylamine ( ... In addition, antioxidants in the rubber industry such as PBNA and N,N0-di- 2-naphthyl-p-phenylenediamine have been shown to be ... PBNA), which contained 2NA (1-2%) as impurities up to the early 1960s until further purification steps were introduced (Weiss ...
5-Amino-o-cresol|5-Nitro-o-cresol| 4-Aminobenzonitrile|Pharmaceutical grade accelerator DM|Scarlet base G|2-Naphthylamine-6...
At present, our main products are 2-Naphthylamine-6-sulfonylmethylamine, 5-Amino-o-cresol, 4-chloro-2-aminodiphenylether, 2- ... amino-2-methyl Diphenyl ether, AE-active ester and 2,5-Dihydro-6-hydroxy-3-mercapto-2-methyl-5-oxo-1,2,4-triazine, etc. ... N,N-Di(2-hydroxyethyl)....... Tel:+86-716-4300061. Contact:Mr. Yao. Mobile:+86-15327688188. E-mail:[email protected] [email protected] ... 2-Naphthylamine-6-sul.... 2-Phenoxyaniline.... 4-chloro-2-aminodiphen.... 2-Nitro-4-methyl-5-met.... 2-(2-Amino-4-thiazolyl... ...
KEGG COMPOUND: C02227
Bladder Cancer: Practice Essentials, Background, Anatomy
2, 3] :. * Low-grade proliferative lesions that develop into non-muscle-invasive tumors; these account for approximately 80% of ... 2] Worldwide, however, SCC is the most common form of bladder cancer, accounting for 75% of cases in developing nations (see ... 53] In one series, 5-year survival rates for grade 1, 2, and 3 SCC was 62%, 52%, and 35%, respectively. [53] In the same study ... Table 2. Recurrence and Progression Rates at 5 Years for Ta, T1, and CIS TCC of the Bladder Treated With BCG ...
Tobacco and chemicals: MedlinePlus Medical Encyclopedia Image
Rule 3745-114-01 - Ohio Administrative Code | Ohio Laws
WHO EMRO | Biological activity resulting from exposure to aquatic environmental genotoxic pollutants in northern Egypt | Volume...
2-naphthylamine and benzidine) in the muscle tissue of fish. There were marked seasonal variations in the aromatic amine levels ... الخلاصـة: قاس الباحثون في بحيرة إدكو والبحر المتوسط، في منطقة المعدية، ثلاثة مركبات أمينية أروماتية هي (1-naphthylamine 2- ... High concentration of 1-naphthylamine and benzidine were found in Tilapia sp. in summer (Table 1) while high concentrations of ... the concentration of 1-naphthylamine was high in all seasons except spring, and high concentrations of 2-naphthylamine and ...
Erowid.org: Erowid Reference 6521 : Asymmetric synthesis of psychotomimetic phenylisopropylamines : Nichols DE, Barfknecht CF,...
Cas 1066-54-2,Trimethylsilylacetylene | lookchem
IARC Publications Website - Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1-42
1-Naphthylamine. * 2-Naphthylamine [superseded by Volume 99]. *1-Naphthylthiourea (ANTU). * Nickel and nickel compounds [ ... 1,2-Dibromo-3-chloropropane [superseded by Volume 71]. * ortho-Dichlorobenzene and para-dichlorobenzene [superseded by Volume ... N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornaphazine) [superseded by Volume 100A] ... 2,3,7,8-Tetrachlorodibenzo-para-dioxin (TCDD) [superseded by Volume 69] ...
Listar por autor "Saad, A.A."
NIOSHTIC-2 Publications Search - 00177506 - Current intelligence bulletins: summaries.
... metabolic precursors of beta-naphthylamine (91598), 2-nitropropane (79469), acrylonitrile (107131), 2,4-diaminoanisole (615054 ... Page last reviewed: September 2, 2020 Content source: National Institute for Occupational Safety and Health Education and ... 2,3,7,8- tetrachlorodibenzo-p-dioxin (1746016), 1,3-butadiene (106990), cadmium (7440439), monohalomethanes, dinitrotoluenes, ...
Chemical Database: 1-Naphthaleneacetamide (EnvironmentalChemistry.com)
1-Naphthylamine, N-acetyl-*2-(1-Naphthyl) acetamide*2-(1-Naphthyl) acetamide [BSI:ISO]*alpha-NAA amide*alpha- ... CAS Number: 86-86-2*Caswell Number: 588*Synonyms/Related:*.alpha.-Naphthaleneacetamide*.alpha.-Naphthaleneacetic acid amide*. ... CO2 Pollution and Global Warming*Compact Fluorescent Lights (CFLs): Are They Worth the Switch?*Global Trends in Energy ... 2, 2011. *US DOT Hazardous Materials Transportation Placards. Hazardous materials placards (DOT placards) are required when ...
What is Potassium stearate
... and N-phenyl-b-naphthylamine are sequentially added to the reactor, the reaction temperature is adjusted to 150-360 deg C, and ... 2. . Used to prepare graphene-modified glue Graphene is included in the existing glue to alter the high-temperature resistance ... Step 2: Mix talcum powder, silica fume along with potassium stearate as well as carboxylated styrene butadiene latex in a high- ... Step 2, adding polyurethane, chloroprene rubber, and polyacrylate into the reactor, the temperature is raised to 80-105 deg C, ...
Urinary Tract Obstruction Management in the ED Clinical Presentation: History, Causes
NIOSHTIC-2 Search Results - Full View
Banche Dati ~ Accredia
- Laboratori di prova
ISO 21527-2:2008. 0. Alimenti con aw,0.95/Food with aw,0.95, Mangimi con aw,0.95/Animal feeding stuffs with aw,0.95. Lieviti/ ... VDI 3866 Blatt 2:2001. 0. Miscela di frutta secca e fichi secchi/Mix dried fruit and dried figs, Uva di Corinto/Currants, Uva ... UNI EN 12457-2:2004, EPA 200.8 1994. 0. Fanghi/Sludges, Rifiuti/Wastes, Terreni (1)/Soils (1). -su eluati da test di cessione/- ... UNI EN 12014-2:2018. II. Acque naturali/Natural waters. Idrocarburi leggeri C,=12 espressi come n-esano/Light hydrocarbons C,= ...
DeCS
Code System Concept
Benzidine4
- 1993. Decrease of CD4-positive T lymphocytes in workers exposed to benzidine and beta-naphthylamine. (cdc.gov)
- الخلاصـة: قاس الباحثون في بحيرة إدكو والبحر المتوسط، في منطقة المعدية، ثلاثة مركبات أمينية أروماتية هي (1-naphthylamine 2-naphthylamine, benzidine) في أنسجة عضلات السمك. (who.int)
- We estimated pollution in Lake Edku and the Mediterranean Sea, El-Maadiya Region, with 3 aromatic amines (1-naphthylamine, 2-naphthylamine and benzidine) in the muscle tissue of fish. (who.int)
- Nous avons réalisé une estimation de la pollution dans le lac Edkou et en Méditerranée (région d'El-Maadiya), sur la base de trois amines aromatiques (1-naphthylamine, 2-naphthylamine et benzidine) dans les tissus musculaires de poissons. (who.int)
Derivatives1
- Synthesis and anticonvulsant properties of new 1-phenyl and 1-phenylamino-3-phenylpyrrolidine-2,5-dione derivatives. (chemchart.com)
Aromatic3
- Employees' exposure to benzo(a)pyrene (50328), other polynuclear-aromatic-hydrocarbons, beta-naphthylamine (91598), aliphatic and aromatic-hydrocarbons were not toxic at concentrations found. (cdc.gov)
- 1-Naphthylamine is an aromatic amine derived from naphthalene. (molbase.com)
- Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant, at least one catalyst, and certain aldehyde-suppressing additives. (justia.com)
Acid1
- We provide (S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic acid as well. (buyersguidechem.com)
Naphthol1
- Effects of genetic polymorphisms in metabolic enzymes on the relationships between 8-hydroxydeoxyguanosine levels in human leukocytes and urinary 1-hydroxypyrene and 2-naphthol concentrations. (cdc.gov)
Methyl2
- Manufacturing Pharma Raw Materials, 1,2-Di Methoxy Ethane (Monoglyme) 1,4-Dioxane 2,4-Dichlorobenzyl chloride 2-Methyl Dimethylaniline. (needsinfo.com)
- Methyl (2S,5R)-(+)-5-phenylpyrrolidine-2-carboxylate. (chemchart.com)
Sulfonyl1
- Manufacturer of 3,3-Diamino-Sulfonyl bis benzene (Cas No. 599-61-1), 2-Amino Sulfonyl bis benzene Dimethylaniline. (needsinfo.com)
Chemicals2
- Gihi Chemicals Co., Limited is supplier for N-Phenyl-1-naphthylamine. (buyersguidechem.com)
- Synthon-Chemicals GmbH & Co. KG is supplier for N-Phenyl-1-naphthylamine. (buyersguidechem.com)
Phenyl6
- Nation Ford Chemical Co. is supplier for N-Phenyl-1-naphthylamine. (buyersguidechem.com)
- Fanwood Chemical, Inc. is supplier for N-Phenyl-1-naphthylamine. (buyersguidechem.com)
- Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical) is supplier for N-Phenyl-1-naphthylamine. (buyersguidechem.com)
- Shanghai Mintchem Development Co., Ltd. is supplier for N-Phenyl-1-naphthylamine. (buyersguidechem.com)
- Xiamen Equation Chemical Co.,Ltd is supplier for N-Phenyl-1-naphthylamine. (buyersguidechem.com)
- In the British rubber industry, the use of b-naphthylamine ended in 1949 and was mainly replaced by N-phenyl- 2-naphthylamine (PBNA), which contained 2NA (1-2%) as impurities up to the early 1960s until further purification steps were introduced (Weiss et al. (cdc.gov)
Suppl1
- Paediatric and perinatal epidemiology 2001 Jul 15 Suppl 2 (): 63-77. (cdc.gov)
20161
- Gene 2016 Nov 593 (2): 277-83. (cdc.gov)
Biochemical1
- Synthesis and biochemical evaluation of analogues of aminoglutethimide based on phenylpyrrolidine-2,5-dione. (chemchart.com)
20021
- Mutation research 2002 Jan 513 (1-2): 37-48. (cdc.gov)
Means1
- Additionally, the Ab's specificity for the hapten dansyl and the convenient chemistry of dansyl provide a means to link IL-2 to virtually any molecule of interest without the complexities and uncertainties of making IL-2 fusions with each molecule individually. (elsevier.com)