2-Aminoadipate Transaminase
L-Aminoadipate-Semialdehyde Dehydrogenase
2-Aminoadipic Acid
Alanine Transaminase
4-Aminobutyrate Transaminase
Transaminases
alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus. (1/6)
The extremely thermophilic bacterium Thermus thermophilus HB27 synthesizes lysine through alpha-aminoadipate (AAA). In this study, a T. thermophilus gene encoding the enzyme that catalyses transamination of AAA was cloned as a mammalian kynurenine/AAA aminotransferase (Kat2) gene homologue. A T. thermophilus mutant with disruption of the Kat2 homologue required a longer lag phase for growth and showed slower growth in minimal medium. Furthermore, addition of AAA or lysine shortened the lag phase and improved the growth rate. The Kat2 homologue was therefore termed lysN. LysN recognizes not only 2-oxoadipate, an intermediate of lysine biosynthesis, but also 2-oxoisocaproate, 2-oxoisovalerate and 2-oxo-3-methylvalerate, intermediates of leucine, valine and isoleucine biosyntheses, respectively, along with oxaloacetate, a compound in the TCA cycle, as an amino acceptor. These results suggest multiple roles of LysN in several cellular metabolic pathways including lysine and branched-chain amino acid biosyntheses. (+info)Purification and properties of kynurenine aminotransferase from rat kidney. (2/6)
Previous reports indicated that a single protein exhibits kynurenine aminotransferase (KAT) and alpha-aminoadipate aminotransferase (AadAT) activities. However, recently we discovered that KAT and AadAT activities are associated with two different proteins. KAT from rat kidney supernatant fraction was purified to electrophoretic homogeneity by (NH4)2SO4 fractionation, DEAE-Sephacel and hydroxyapatite chromatography. This procedure separated KAT from AadAT and improved the overall yield and the degree of purification over previously published methods. Some of the properties of purified KAT, such as Mr, subunit structure and the inhibition by dicarboxylic acids, were identical with those reported previously. However, the substrate specificity and pI of purified KAT were different from earlier reports. The same procedure can also be used to purify KAT from rat kidney mitochondria. These results support our earlier observation that KAT and AadAT activities are associated with two proteins and suggest that cytosolic KAT may be structurally similar to the mitochondrial enzyme. (+info)Alpha-aminoadipate and kynurenine aminotransferase activities from rat kidney. Evidence for separate identity. (3/6)
alpha-Aminoadipate aminotransferase and kynurenine aminotransferase activities from rat kidney are reportedly associated with the same protein. We observed that when the supernatant fraction was maintained at pH 4.5 for 75 min, 100% of kynurenine aminotransferase activity was lost, whereas only 40% of aminoadipate aminotransferase activity was lost. We purified alpha-aminoadipate aminotransferase and kynurenine aminotransferase from rat kidney supernatant fraction to electrophoretic homogeneity by ammonium sulfate fractionation, DEAE-Sephacel, and hydroxylapatite chromatography. Kynurenine aminotransferase activity was precipitated by pH treatment. The remaining aminoadipate aminotransferase activity was concentrated and injected into rabbits to raise antibodies that were used to prepare an affinity column. A mixture of aminoadipate aminotransferase and kynurenine aminotransferase activities obtained after hydroxylapatite chromatography was subjected to affinity chromatography. Aminoadipate aminotransferase and kynurenine aminotransferase activities resolved as separate peaks, providing evidence that the two activities are associated with two different proteins. (+info)Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I. (4/6)
(+info)Purification and properties of 2-aminoadipate: 2-oxoglutarate aminotransferase from bovine kidney. (5/6)
Previous studies with rat kidney preparations indicated that 2-aminoadipate aminotransferase (AadAT) and kynurenine aminotransferase (KAT) activities are properties of a single protein. We found that bovine kidney contains an appreciable amount of AadAT activity, but lacks KAT activity. AadAT from bovine and rat kidney extracts were purified to electrophoretic homogeneity. The purification procedure included fractionation with (NH1)2SO1, heat treatment, DEAE-cellulose chromatography and hydroxyapatite chromatography. Physical and kinetic properties, such as pH optima, Km for substrates, Mr, electrophoretic mobility and inhibition by dicarboxylic acids of bovine kidney AadAT, were similar to those of the rat kidney enzyme. However, bovine kidney AadAT differed from rat kidney AadAT in substrate specificity, amino acid composition and stability when stored. The titration curve of bovine kidney AadAT was also different from that of the rat kidney enzyme. The results suggest that bovine kidney AadAT may have some structural similarity to rat kidney AadAT and that the structural differences observed between the two enzymes may explain the absence of KAT activity in bovine kidney. (+info)Cloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney. (6/6)
Several aminotransferases with kynurenine aminotransferase (KAT) activity are able to convert L-kynurenine into kynurenic acid, a putative endogenous modulator of glutamatergic neurotransmission. In the rat, one of the described KAT isoforms has been found to correspond to glutamine transaminase K. In addition, rat kidney alpha-aminoadipate aminotransferase (AadAT) also shows KAT activity. In this report, we describe the isolation of a cDNA clone encoding the soluble form of this aminotransferase isoenzyme from rat (KAT/AadAT). Degenerate oligonucleotides were designed from the amino acid sequences of rat kidney KAT/AadAT tryptic peptides for use as primers for reverse transcription-polymerase chain reaction of rat kidney RNA. The resulting polymerase chain reaction fragment was used to screen a rat kidney cDNA library and to isolate a cDNA clone encoding KAT/AadAT. Analysis of the combined DNA sequences indicated the presence of a single 1275-base pair open reading frame coding for a soluble protein of 425 amino acid residues. KAT/AadAT appears to be structurally homologous to aspartate aminotransferase in the pyridoxal 5'-phosphate binding domain. RNA blot analysis of rat tissues, including brain, revealed a single species of KAT/AadAT mRNA of approximately 2.1 kilobases. HEK-293 cells transfected with the KAT/AadAT cDNA exhibited both KAT and AadAT activities with enzymatic properties similar to those reported for the rat native protein. (+info)
AADAT - Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial precursor - Homo sapiens (Human) - AADAT gene & protein
Sequence Similarity Search - BLAST
AADAT Antibody - Cat. No. 48-417 | ProSci
Q8N5Z0 | AADAT - Overview | canSAR Black
The α-aminoadipate pathway for lysine biosynthesis in fungi | SpringerLink
AADAT Fragment MS Protein Standard - Creative Proteomics
EC 2.6.1.105
Raxone 150 mg film-coated tablets | Patient Info | Chiesi Limited | Medicines.ie
KYAT1 (kynurenine aminotransferase 1) - KOMP (Knockout Mouse Project)
Olympian Labs Melatonin 5mg Fast Dissolve 60 Tab -- VitaGlo
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CH00115
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DLL1 | Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors
RNAP | Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors
Kynurenine aminotransferase 3/glutamine transaminase L/cysteine conjugate beta-lyase 2 is a major glutamine transaminase in the...
Lysine metabolism in mammalian brain: An update on the importance of recent discoveries<...
Measurement of the Activity of a Kynurenine-Converting Enzyme and/or a Kynurenic-Acid, Anthranilic-Acid and/or 3...
Glutaricaciduria I - NORD (National Organization for Rare Disorders)
Glutaric aciduria type I
Glutaric aciduria type I - ONA
Page 2 - Clinical Advisor
KEGG PATHWAY: Penicillin and cephalosporin biosynthesis - Reference pathway
Human Metabolome Database: Showing metabocard for Aminoadipic acid (HMDB0000510)
Test | Invitae Glutaric Acidemia Type I Test
RCSB PDB
for 1E5Q
3-methylglutaconic aciduria type I
Glutaric aciduria type 1 | definition of Glutaric aciduria type 1 by Medical dictionary
2017/18 ICD-10-CM Diagnosis Code E71.313: Glutaric aciduria type II
List of MeSH codes (D08)
... glycine transaminase MeSH D08.811.913.477.700.535 - leucine transaminase MeSH D08.811.913.477.700.550 - l-lysine 6-transaminase ... l-aminoadipate-semialdehyde dehydrogenase MeSH D08.811.682.657.163.812 - malonate-semialdehyde dehydrogenase (acetylating) MeSH ... beta-alanine-pyruvate transaminase MeSH D08.811.913.477.700.347 - d-alanine transaminase MeSH D08.811.913.477.700.470 - ... transaminases MeSH D08.811.913.477.700.100 - alanine transaminase MeSH D08.811.913.477.700.120 - 2-aminoadipate transaminase ...
List of EC numbers (EC 2)
... aspartate transaminase EC 2.6.1.2: alanine transaminase EC 2.6.1.3: cysteine transaminase EC 2.6.1.4: glycine transaminase EC ... D-amino-acid transaminase EC 2.6.1.11: acetylornithine transaminase EC 2.6.1.12: alanine-oxo-acid transaminase EC 2.6.1.13: ... UDP-N-acetylbacillosamine transaminase EC 2.6.1.35: glycine-oxaloacetate transaminase EC 2.6.1.36: L-lysine 6-transaminase EC ... glutamine-phenylpyruvate transaminase EC 2.6.1.65: N6-acetyl-β-lysine transaminase EC 2.6.1.66: valine-pyruvate transaminase EC ...
2-aminoadipate transaminase
... glutamic-ketoadipic transaminase, and glutamate-alpha-ketoadipate transaminase. This enzyme participates in lysine biosynthesis ... Matsuda M, Ogur M (1969). "Separation and specificity of the yeast glutamate-alpha-ketoadipate transaminase". J. Biol. Chem. ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ... Other names in common use include alpha-aminoadipate aminotransferase, 2-aminoadipate aminotransferase, 2-aminoadipic ...
Lysine-pyruvate 6-transaminase
In enzymology, a lysine-pyruvate 6-transaminase (EC 2.6.1.71) is an enzyme that catalyzes the chemical reaction L-lysine + ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ... 49 (2): 203-206. doi:10.1111/j.1574-6968.1988.tb02716.x. Portal: Biology v t e (EC 2.6.1, Enzymes of unknown structure, All ... L-2-aminoadipate 6-semialdehyde + L-alanine Thus, the two substrates of this enzyme are L-lysine and pyruvate, whereas its two ...
L-lysine 6-transaminase
... belongs to the aminotransferase class-III family. Crystal structures of L-lysine 6-transaminase reveal ... In enzymology, a L-lysine 6-transaminase (EC 2.6.1.36) is an enzyme that catalyzes the chemical reaction L-lysine + 2- ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. This ... Other names in common use include lysine 6-aminotransferase, lysine epsilon-aminotransferase, lysine epsilon-transaminase, ...
AADAT
It converts alpha-aminoadipate to alpha-ketoadipate. It is also one of the Kynurenine-oxoglutarate transaminases. GRCh38: ... Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, also known as alpha-aminoadipate aminotransferase and kynurenine ... PDBe-KB provides an overview of all the structure information available in the PDB for Human Kynurenine/alpha-aminoadipate ... "Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT)". Molecular Genetics and Metabolism. 76 ...
Kynurenine-oxoglutarate transaminase
Han Q, Cai T, Tagle DA, Robinson H, Li J (August 2008). "Substrate specificity and structure of human aminoadipate ... Han Q, Cai T, Tagle DA, Robinson H, Li J (August 2008). "Substrate specificity and structure of human aminoadipate ... In enzymology, a kynurenine-oxoglutarate transaminase (EC 2.6.1.7) is an enzyme that catalyzes the chemical reaction L- ... This enzyme belongs to the family of transferases, to be specific, the transaminases, that transfer nitrogenous groups. The ...
Kynurenic acid
It is formed from L-kynurenine in a reaction catalyzed by the enzyme kynurenine-oxoglutarate transaminase. KYNA has been ... "Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II". Bioscience Reports ... 92 (1-2): 203-9. doi:10.1016/j.physbeh.2007.05.025. PMID 17573079. S2CID 46156877. Erhardt S, Schwieler L, Engberg G (2003). " ... 330 (2): 265-72. doi:10.1016/0006-8993(85)90685-7. PMID 2985194. S2CID 24345638. Hilmas C, Pereira EF, Alkondon M, Rassoulpour ...
Biosynthesis
There are two distinct lysine biosynthetic pathways: the diaminopimelic acid pathway and the α-aminoadipate pathway. The most ... "MetaCyc: L-lysine biosynthesis I". PETERKOFSKY, B; GILVARG, C (May 1961). "N-Succinyl-L-diaminopimelic-glutamic transaminase". ... This reaction that removes the 2'-OH of the ribose sugar to generate deoxyribose is not affected by the bases attached to the ... 10 (2): 113-127. doi:10.1038/nrm2838. PMC 4461372. PMID 20094052. Green, Rachel; Harry F. Noller; et al. (1997). "Ribosomes and ...
Finding step lysJ for L-lysine biosynthesis in Desulfovibrio vulgaris Hildenborough
Curated proteins matching [LysW]-aminoadipate semialdehyde transaminase. *Curated proteins matching [LysW]-aminoadipate ... LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 35%. 81%. 150.6. glutamate-1-semialdehyde 2,1- ... Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 33%. 57%. 99. ... Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.-; EC 2.6.1.118 (characterized, see ...
B6db activities : 2 6 1 105
EC 2.6.1.62, adenosylmethionine 8-amino-7-oxononanoate transaminase).. The second product of the reaction, (S)-2-amino-6- ... Lysine--8-amino-7-oxononanoate transaminase. Alternative names. DAPA aminotransferase (ambiguous);. bioA (gene name) (ambiguous ... L-lysine + 8-amino-7-oxononanoate = (S)-2-amino-6-oxohexanoate + 7,8-diaminononanoate.. ...
HOMD :: SEQF3145
2-aminoadipate transaminase. 64. SEQF3145,RYFV01000011.1. SEQF3145_00065 jb [NA] [AA] 957/318. 77403-78359. D-alanine--D- ... Acyl-CoA thioesterase 2. 99. SEQF3145,RYFV01000012.1. SEQF3145_00100 jb [NA] [AA] 1698/565. 32130-30433. Phosphoenolpyruvate- ... 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase. 24. SEQF3145,RYFV01000011.1. SEQF3145_00024 jb [NA] [AA] 600/ ... tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase. 173. SEQF3145,RYFV01000013.1. SEQF3145_00181 jb [NA] [AA] 1077/358. ...
Model Search | BioModels
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (3) * V-type proton ATPase subunit D (3) ... Probable kynurenine--oxoglutarate transaminase BNA3 (3) * Cystathionine gamma-synthase (3) * Thioredoxin-3, mitochondrial (3) ... Dolichyl-phosphate-mannose--protein mannosyltransferase 2 (4) * 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate ... 1-phosphatidylinositol 3-phosphate 5-kinase FAB1 (2) * Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W (2 ...
Enzyme
Alanine transaminase. Alanine--glyoxylate transaminase. Alanine--oxo-acid transaminase. Alanine--oxomalonate transaminase. ... Aminoadipate-semialdehyde dehydrogenase. Aminobenzoate decarboxylase. Aminobutyraldehyde dehydrogenase. Aminocarboxymuconate- ... Asparagine--oxo-acid transaminase. Asparagine--tRNA ligase. Asparaginyl-tRNA synthase (glutamine-hydrolyzing). Asparagusate ... Aspartate transaminase. Aspartate--ammonia ligase. Aspartate--ammonia ligase (ADP-forming). Aspartate--phenylpyruvate ...
MMTB
2.6.1.5 tyrosine transaminase 2.6.1.51 serine---pyruvate transaminase 2.6.1.58 phenylalanine(histidine) transaminase - - - - - ... 2.6.1.2 alanine transaminase 2.6.1.44 alanine---glyoxylate transaminase 2.6.1.7 kynurenine---oxoglutarate transaminase - - - - ... 2.6.1.18 beta-alanine---pyruvate transaminase 2.6.1.2 alanine transaminase 2.6.1.4 glycine transaminase 2.6.1.40 (R)-3-amino-2- ... 2.6.1.51 serine---pyruvate transaminase 2.6.1.84 arginine---pyruvate transaminase 2.6.1.9 histidinol-phosphate transaminase - - ...
Protein CCNA 00620 in Caulobacter crescentus NA1000
Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.-; EC 2.6.1.118 (characterized, see ... Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.-; EC 2.6.1.118 (characterized, see ... Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.-; EC 2.6.1.118 (characterized, see ... Succinylornithine transaminase; SOAT; Succinylornithine aminotransferase; EC 2.6.1.81. 49%. 341.7. L-proline biosynthesis. argD ...
MMTB
1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase 1.2.1.48 long-chain-aldehyde dehydrogenase 1.2.1.5 aldehyde dehydrogenase [ ... 2.6.1.18 beta-alanine---pyruvate transaminase - BRENDA: BS422438 benzaldehyde + 2-oxoglutarate <=> (5R)-5-hydroxy-4-oxo-5- ... S)-2-nitro-1-phenylethanol <=> Nitromethane + benzaldehyde + (R)-2-nitro-1-phenylethanol 4.1.2.47 (S)-hydroxynitrile lyase - ... benzaldehyde + acetaldehyde <=> (R)-benzoin + (S)-2-Hydroxypropiophenone 4.1.1.7 benzoylformate decarboxylase - BRENDA: ...
L-proline biosynthesis in Sinorhizobium meliloti 1021
... glutamate semialdehyde transaminase. SMc02138. SM_b21186. lysK. [LysW]-lysine hydrolase / [LysW]-ornithine hydrolase. ... LysW]-2-aminoadipate 6-phosphate reductase / [LysW]-glutamylphosphate reductase. lysZ. [LysW]-2-aminoadipate 6-kinase / [LysW]- ... there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, ...
i5k - EOG8RNDVB
transaminase activity. 4. GO:0047536. 2-aminoadipate transaminase activity. 1. GO:0003700. transcription factor activity, ...
Protein 3607958 in Dinoroseobacter shibae DFL-12
LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 31%. 94%. 193.7. beta-alanine-pyruvate transaminase ... LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 31%. 94%. 193.7. beta-alanine-pyruvate transaminase ... LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 31%. 94%. 193.7. beta-alanine-pyruvate transaminase ... beta-alanine-pyruvate transaminase (EC 2.6.1.18). 65%. 568.5. L-proline biosynthesis. argD. lo. Acetylornithine ...
YJR139C 267.488705 INESSENTIAL HOM6 "Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase),5-amino-6-(5...
... "aminoadipate-semialdehyde dehydrogenase small subunit (alpha-aminoadipate reductase), amino acid biosynthesis, aminoadipate- ... "phosphoserine transaminase,phosphoserine aminotransferase," YHR025W 143.39381 INESSENTIAL THR1 "homoserine kinase,homoserine ... transaminase (4-aminobutyrate aminotransferase),4-aminobutyrate aminotransferase, " YGR072W 8.896687 INESSENTIAL UPF3 "involved ... "Branched-Chain Amino Acid Transaminase,branched-chain amino acid aminotransferase," YEL065W -0.945446 INESSENTIAL SIT1 " ...
Aspartate Aminotransferases | Profiles RNS
Transaminase, Glutamic-Oxaloacetic. *L-Aspartate-2-Oxoglutarate Aminotransferase. *Aminotransferase, L-Aspartate-2-Oxoglutarate ... Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L- ... Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation decreases ... attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2- ...
Tryptophan Transaminase | Profiles RNS
"Tryptophan Transaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Tryptophan Transaminase" by people in this website by year, ... Below are the most recent publications written about "Tryptophan Transaminase" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Tryptophan Transaminase". ...
ISMARA results: LHX6
aminoadipate aminotransferase. chr3_+_108541545. 0.13. ENST00000295756.6. TRAT1. T cell receptor associated transmembrane ... LIM domain only 2 (rhombotin-like 1). chr11_+_67798090. 0.13. ENST00000313468.5. NDUFS8. NADH dehydrogenase (ubiquinone) Fe-S ... thymidine kinase 2, mitochondrial. chr14_+_104182105. 0.07. ENST00000311141.2. ZFYVE21. zinc finger, FYVE domain containing 21 ... NudC domain containing 2. chr12_+_95611569. 0.08. ENST00000261219.6. ENST00000551472.1. ENST00000552821.1. VEZT. vezatin, ...
Curated BLAST
Dsui_2708: succinyldiaminopimelate transaminase. is similar to:. PaperBLAST. ArAT1 / D7F4K3: aromatic amino acid transaminase ( ... ARO8_YEAST / P53090: Aromatic/aminoadipate aminotransferase 1; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; ... tyrB / GB,AAC77024.1: aromatic-amino-acid transaminase TyrB; EC 2.6.1.57 from Escherichia coli. tyrB / P04693: tyrosine ... tyrB / GB,AAC77024.1: aromatic-amino-acid transaminase TyrB; EC 2.6.1.57 from Escherichia coli. tyrB / P04693: tyrosine ...
KEGG ORTHOLOGY: K05830
2.6.1 Transaminases. 2.6.1.118 [amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase. K05830 lysJ, argD; [ ... and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through alpha-aminoadipate. ... Aminotransferase (transaminase). Class III. K05830 lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L- ... Ontology (5) KEGG BRITE (3) COG (2) Pathway (14) KEGG PATHWAY (12) KEGG MODULE (2) Chemical reaction (6) KEGG ENZYME (2) KEGG ...
Aligments for a candidate for lysN in Pseudomonas fluorescens FW300-N1B4
Transaminase A; EC 2.6.1.1; EC 2.6.1.39 (characterized) to candidate Pf1N1B4_4425 Aspartate aminotransferase (EC 2.6.1.1) ... Align Aspartate aminotransferase; AAT; AspAT; Putative 2-aminoadipate transaminase; ... 2 Number of sequences better than 1.0e-02: 1 Number of HSP's gapped: 1 Number of HSP's successfully gapped: 1 Length of query: ... there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, ...
Model Search | BioModels
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (3) * V-type proton ATPase subunit D (3) ... Probable kynurenine--oxoglutarate transaminase BNA3 (3) * Cystathionine gamma-synthase (3) * Thioredoxin-3, mitochondrial (3) ... Dolichyl-phosphate-mannose--protein mannosyltransferase 2 (4) * 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate ... 1-phosphatidylinositol 3-phosphate 5-kinase FAB1 (2) * Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W (2 ...
L-arginine biosynthesis in Sinorhizobium meliloti 1021
... glutamate semialdehyde transaminase. SMc02138. SM_b21186. lysK. [LysW]-lysine hydrolase / [LysW]-ornithine hydrolase. ... LysW]-2-aminoadipate 6-kinase / [LysW]-glutamate kinase. SMc01726. Confidence: high confidence medium confidence low confidence ... 2-aminoadipate/glutamate carrier protein. lysY. [LysW]-2-aminoadipate 6-phosphate reductase / [LysW]-glutamylphosphate ... there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, ...
L-lysine biosynthesis in Phaeobacter inhibens BS107
... lysZYJ convert LysW-aminoadipate to LysW-lysine, and lysK releases lysine. ... glutamate semialdehyde transaminase. PGA1_c24230. PGA1_c28750. ... Comment: 2-oxoglutarate and acetyl-CoA are converted to ... 2-aminoadipate-LysW ligase. lysY. [LysW]-2-aminoadipate 6-phosphate reductase / [LysW]-glutamylphosphate reductase. PGA1_c17050 ... LysW]-2-aminoadipate 6-kinase / [LysW]-glutamate kinase. PGA1_c02050. Confidence: high confidence medium confidence low ...
DeCS
Glutamine fructose 6-phosphate transaminase (isomerizing) [D08.811.913.477.700.500] Glutamine fructose 6-phosphate transaminase ... aminoadipate aminotransférase 2-aminoadipate: 2-oxoglutarate aminotransférase AadAT alpha-Aminoadipate aminotransférase ... aminoadipate aminotransférase. 2-aminoadipate: 2-oxoglutarate aminotransférase. AadAT. alpha-Aminoadipate aminotransférase. ... 2-aminoadipato transaminasa. Note dapplication:. Enzima que contiene PIRIDOXAL FOSFATO que cataliza la transferencia del grupo ...
i5k - EOG8RNDVB
Aligments for a candidate for lysN in Pseudomonas fluorescens FW300-N1B4
Transaminase A; EC 2.6.1.1; EC 2.6.1.39 (characterized) to candidate Pf1N1B4_4425 Aspartate aminotransferase (EC 2.6.1.1) ... Align Aspartate aminotransferase; AAT; AspAT; Putative 2-aminoadipate transaminase; ... 2 Number of sequences better than 1.0e-02: 1 Number of HSPs gapped: 1 Number of HSPs successfully gapped: 1 Length of query: ... there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, ...
ISMARA results: LHX6
aminoadipate aminotransferase. chr3_+_108541545. 0.13. ENST00000295756.6. TRAT1. T cell receptor associated transmembrane ... LIM domain only 2 (rhombotin-like 1). chr11_+_67798090. 0.13. ENST00000313468.5. NDUFS8. NADH dehydrogenase (ubiquinone) Fe-S ... thymidine kinase 2, mitochondrial. chr14_+_104182105. 0.07. ENST00000311141.2. ZFYVE21. zinc finger, FYVE domain containing 21 ... NudC domain containing 2. chr12_+_95611569. 0.08. ENST00000261219.6. ENST00000551472.1. ENST00000552821.1. VEZT. vezatin, ...
DeCS 2011 - December 22, 2011 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2014 - December 16, 2014 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2011 - December 22, 2011 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2014 - December 16, 2014 version
DeCS 2011 - December 22, 2011 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2016 - July 28, 2016 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2009 - February 20, 2009 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Fluoro-2-deoxyglucose use Fluorodeoxyglucose F18 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10- ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Oxoisovalerate Dehydrogenase (Lipoamide) use 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) 2-PAM Compounds use ...
DeCS 2010 - February 12, 2010 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-Glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2009 - February 20, 2009 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Fluoro-2-deoxyglucose use Fluorodeoxyglucose F18 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10- ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Oxoisovalerate Dehydrogenase (Lipoamide) use 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) 2-PAM Compounds use ...
DeCS 2012 - February 22, 2012 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2013 - July 15, 2013 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2013 - December 17, 2013 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
DeCS 2012 - February 22, 2012 version
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
MMTB
2.6.1.74 cephalosporin-C transaminase - BRENDA: BS356888 D-Aspartate + 2-oxoadipate <=> oxaloacetate + 2-Aminoadipate 2.6.1.74 ... 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase - - BRENDA: BS396383 D-serine + 2-oxoadipate <=> Hydroxypyruvate + 2- ... ATP + 2-Aminoadipate + L-cysteine <=> ADP + phosphate + DL-aminoadipyl-L-cysteine 6.3.2.2 glutamate---cysteine ligase - ... 2-piperidone-6-carboxylate + ATP + H2O <=> 2-Aminoadipate + phosphate + ADP 3.5.2.9 5-oxoprolinase (ATP-hydrolysing) - ...
MMTB
2.6.1.5 tyrosine transaminase 2.6.1.51 serine---pyruvate transaminase 2.6.1.58 phenylalanine(histidine) transaminase - - - - - ... 2.6.1.2 alanine transaminase 2.6.1.44 alanine---glyoxylate transaminase 2.6.1.7 kynurenine---oxoglutarate transaminase - - - - ... 2.6.1.18 beta-alanine---pyruvate transaminase 2.6.1.2 alanine transaminase 2.6.1.4 glycine transaminase 2.6.1.40 (R)-3-amino-2- ... 2.6.1.51 serine---pyruvate transaminase 2.6.1.84 arginine---pyruvate transaminase 2.6.1.9 histidinol-phosphate transaminase - - ...
Tryptophan Transaminase | Colorado PROFILES
"Tryptophan Transaminase" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Tryptophan Transaminase" by people in this website by year, ... Below are the most recent publications written about "Tryptophan Transaminase" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Tryptophan Transaminase". ...
Human Metabolome Database: HMDB0000978 (4-(2-Aminophenyl)-2,4-dioxobutanoic acid) Protein Associations
Kynurenine--oxoglutarate transaminase 1. Q16773 CCBL1. 9q34.11. Enzyme. Not Available. HMDBP03053. Aminoadipate ... Kynurenine--oxoglutarate transaminase 3. Q6YP21 CCBL2. 1p22.2. Enzyme. Not Available. Displaying all 5 metabolite protein links ... Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial. Q8N5Z0 AADAT. 4q33. Enzyme. Not Available. HMDBP00464. ...
Tryptophan Transaminase | Profiles RNS
"Tryptophan Transaminase" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Tryptophan Transaminase" by people in this website by year, ... Below are the most recent publications written about "Tryptophan Transaminase" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Tryptophan Transaminase". ...
List of EC numbers (EC 2)
EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of ... alanine transaminase. *: cysteine transaminase. *: glycine transaminase. *: tyrosine transaminase. *: leucine transaminase. *: ... thyroid-hormone transaminase. *: tryptophan transaminase. *: tryptophan-phenylpyruvate transaminase. *: diamine transaminase. ... b-alanine-pyruvate transaminase. *: 4-aminobutyrate transaminase. *: deleted. *: D-amino acid transaminase. *: (S)-3-amino-2- ...
KEGG ORTHOLOGY: K05830
2.6.1 Transaminases. 2.6.1.118 [amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase. K05830 lysJ, argD; [ ... and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through alpha-aminoadipate. ... Aminotransferase (transaminase). Class III. K05830 lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L- ... Ontology (5) KEGG BRITE (3) COG (2) Pathway (14) KEGG PATHWAY (12) KEGG MODULE (2) Chemical reaction (6) KEGG ENZYME (2) KEGG ...
DeCS 2008 - May 16, 2008 version
4-Aminobutyrate Transaminase. 4-Aminobutyric Acid use gamma-Aminobutyric Acid. 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- ... 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester ... 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
B6db references : 91350058
The levels of glutamate-alpha-ketoadipate transaminase, an enzyme responsible for the conversion of alpha- aminoadipate to ... Use of alpha-aminoadipate and lysine as sole nitrogen source by Schizosaccharomyces pombe and selected pathogenic fungi. ... ketoadipate and alpha-aminoadipate-delta-semialdehyde when grown in medium containing alpha-aminoadipate and lysine, ... Also, 14C-alpha-aminoadipate was converted to 14C-alpha-ketoadipate in vivo. In the ammonium sulfate medium, S. pombe cells ...
YOR184W 2167.216480 INESSENTIAL SER1 phosphoserine transaminase,phosphoserine aminotransferase
... alpha-aminoadipate reductase), amino acid biosynthesis, aminoadipate-semialdehyde dehydrogenase, cytoplasm YOR303W 1230.967166 ... YOR184W 2167.216480 INESSENTIAL SER1 phosphoserine transaminase,phosphoserine aminotransferase, YJR109C 1533.292175 INESSENTIAL ... transaminase (4-aminobutyrate aminotransferase),4-aminobutyrate aminotransferase, YBR094W -0.939813 INESSENTIAL biological_ ... 2.258234 INESSENTIAL BAT2 Branched-Chain Amino Acid Transaminase,branched-chain amino acid aminotransferase, YDR109C -2.259435 ...
Aspartate Aminotransferases | Profiles RNS
Transaminase, Glutamic-Oxaloacetic. *L-Aspartate-2-Oxoglutarate Aminotransferase. *Aminotransferase, L-Aspartate-2-Oxoglutarate ... Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L- ... Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation decreases ... attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2- ...
Alpha-aminoadipate8
- The fission yeast Schizosaccharomyces pombe and pathogenic fungi Candida albicans, Filobasidiella neoformans and Aspergillus fumigatus grew in the medium containing alpha-aminoadipate as the sole nitrogen source. (unipr.it)
- When grown in the alpha-aminoadipate medium, only S. pombe accumulated a significant amount of alpha-ketoadipate in the culture supernatant. (unipr.it)
- Also, 14C-alpha-aminoadipate was converted to 14C-alpha-ketoadipate in vivo. (unipr.it)
- In the ammonium sulfate medium, S. pombe cells converted 14C- alpha-aminoadipate to lysine. (unipr.it)
- The levels of glutamate-alpha-ketoadipate transaminase, an enzyme responsible for the conversion of alpha- aminoadipate to alpha-ketoadipate, and alpha-aminoadipate reductase, an enzyme required for the conversion of alpha-aminoadipate to lysine, were similar in S. pombe cells grown in the alpha-aminoadipate or ammonium sulfate medium. (unipr.it)
- However, the level of homoisocitrate dehydrogenase, an enzyme before the alpha-ketoadipate step, was twelvefold lower in S. pombe cells grown in the alpha-aminoadipate medium compared to the level in cells grown in the ammonium sulfate medium. (unipr.it)
- Pathogenic fungi used in this study did not accumulate alpha- ketoadipate and alpha-aminoadipate-delta-semialdehyde when grown in medium containing alpha-aminoadipate and lysine, respectively, as sole nitrogen source. (unipr.it)
- However, only pathogenic fungi used both lysine and alpha-aminoadipate as sole nitrogen source. (unipr.it)
Mitochondrial1
- Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization. (musc.edu)
Enzyme1
- A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of amino group of L-2-aminoadipate onto 2-oxoglutarate to generate 2-oxoadipate and L-GLUTAMATE. (bvsalud.org)
Transferases1
- This list contains a list of EC numbers for the second group, EC 2 , transferases , placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology . (en-academic.com)
Biosynthesis1
- For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. (lbl.gov)
Minor topic1
- This graph shows the total number of publications written about "Tryptophan Transaminase" by people in this website by year, and whether "Tryptophan Transaminase" was a major or minor topic of these publications. (ucdenver.edu)
Conversion1
- Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. (musc.edu)
People1
- Below are the most recent publications written about "Tryptophan Transaminase" by people in Profiles. (ucdenver.edu)