A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of amino group of L-2-aminoadipate onto 2-oxoglutarate to generate 2-oxoadipate and L-GLUTAMATE.
An enzyme that catalyzes the oxidation of L-2-aminoadipate 6-semialdehyde to L-2-aminoadipate (alpha-aminoadipic acid). It is involved in the biosynthetic pathway of LYSINE.
A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC 2.6.1.2.
An enzyme that converts brain gamma-aminobutyric acid (GAMMA-AMINOBUTYRIC ACID) into succinate semialdehyde, which can be converted to succinic acid and enter the citric acid cycle. It also acts on beta-alanine. EC 2.6.1.19.
A subclass of enzymes of the transferase class that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Most of these enzymes are pyridoxyl phosphate proteins. (Dorland, 28th ed) EC 2.6.1.
Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. EC 2.6.1.1.

alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus. (1/6)

The extremely thermophilic bacterium Thermus thermophilus HB27 synthesizes lysine through alpha-aminoadipate (AAA). In this study, a T. thermophilus gene encoding the enzyme that catalyses transamination of AAA was cloned as a mammalian kynurenine/AAA aminotransferase (Kat2) gene homologue. A T. thermophilus mutant with disruption of the Kat2 homologue required a longer lag phase for growth and showed slower growth in minimal medium. Furthermore, addition of AAA or lysine shortened the lag phase and improved the growth rate. The Kat2 homologue was therefore termed lysN. LysN recognizes not only 2-oxoadipate, an intermediate of lysine biosynthesis, but also 2-oxoisocaproate, 2-oxoisovalerate and 2-oxo-3-methylvalerate, intermediates of leucine, valine and isoleucine biosyntheses, respectively, along with oxaloacetate, a compound in the TCA cycle, as an amino acceptor. These results suggest multiple roles of LysN in several cellular metabolic pathways including lysine and branched-chain amino acid biosyntheses.  (+info)

Purification and properties of kynurenine aminotransferase from rat kidney. (2/6)

Previous reports indicated that a single protein exhibits kynurenine aminotransferase (KAT) and alpha-aminoadipate aminotransferase (AadAT) activities. However, recently we discovered that KAT and AadAT activities are associated with two different proteins. KAT from rat kidney supernatant fraction was purified to electrophoretic homogeneity by (NH4)2SO4 fractionation, DEAE-Sephacel and hydroxyapatite chromatography. This procedure separated KAT from AadAT and improved the overall yield and the degree of purification over previously published methods. Some of the properties of purified KAT, such as Mr, subunit structure and the inhibition by dicarboxylic acids, were identical with those reported previously. However, the substrate specificity and pI of purified KAT were different from earlier reports. The same procedure can also be used to purify KAT from rat kidney mitochondria. These results support our earlier observation that KAT and AadAT activities are associated with two proteins and suggest that cytosolic KAT may be structurally similar to the mitochondrial enzyme.  (+info)

Alpha-aminoadipate and kynurenine aminotransferase activities from rat kidney. Evidence for separate identity. (3/6)

alpha-Aminoadipate aminotransferase and kynurenine aminotransferase activities from rat kidney are reportedly associated with the same protein. We observed that when the supernatant fraction was maintained at pH 4.5 for 75 min, 100% of kynurenine aminotransferase activity was lost, whereas only 40% of aminoadipate aminotransferase activity was lost. We purified alpha-aminoadipate aminotransferase and kynurenine aminotransferase from rat kidney supernatant fraction to electrophoretic homogeneity by ammonium sulfate fractionation, DEAE-Sephacel, and hydroxylapatite chromatography. Kynurenine aminotransferase activity was precipitated by pH treatment. The remaining aminoadipate aminotransferase activity was concentrated and injected into rabbits to raise antibodies that were used to prepare an affinity column. A mixture of aminoadipate aminotransferase and kynurenine aminotransferase activities obtained after hydroxylapatite chromatography was subjected to affinity chromatography. Aminoadipate aminotransferase and kynurenine aminotransferase activities resolved as separate peaks, providing evidence that the two activities are associated with two different proteins.  (+info)

Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I. (4/6)

 (+info)

Purification and properties of 2-aminoadipate: 2-oxoglutarate aminotransferase from bovine kidney. (5/6)

Previous studies with rat kidney preparations indicated that 2-aminoadipate aminotransferase (AadAT) and kynurenine aminotransferase (KAT) activities are properties of a single protein. We found that bovine kidney contains an appreciable amount of AadAT activity, but lacks KAT activity. AadAT from bovine and rat kidney extracts were purified to electrophoretic homogeneity. The purification procedure included fractionation with (NH1)2SO1, heat treatment, DEAE-cellulose chromatography and hydroxyapatite chromatography. Physical and kinetic properties, such as pH optima, Km for substrates, Mr, electrophoretic mobility and inhibition by dicarboxylic acids of bovine kidney AadAT, were similar to those of the rat kidney enzyme. However, bovine kidney AadAT differed from rat kidney AadAT in substrate specificity, amino acid composition and stability when stored. The titration curve of bovine kidney AadAT was also different from that of the rat kidney enzyme. The results suggest that bovine kidney AadAT may have some structural similarity to rat kidney AadAT and that the structural differences observed between the two enzymes may explain the absence of KAT activity in bovine kidney.  (+info)

Cloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney. (6/6)

Several aminotransferases with kynurenine aminotransferase (KAT) activity are able to convert L-kynurenine into kynurenic acid, a putative endogenous modulator of glutamatergic neurotransmission. In the rat, one of the described KAT isoforms has been found to correspond to glutamine transaminase K. In addition, rat kidney alpha-aminoadipate aminotransferase (AadAT) also shows KAT activity. In this report, we describe the isolation of a cDNA clone encoding the soluble form of this aminotransferase isoenzyme from rat (KAT/AadAT). Degenerate oligonucleotides were designed from the amino acid sequences of rat kidney KAT/AadAT tryptic peptides for use as primers for reverse transcription-polymerase chain reaction of rat kidney RNA. The resulting polymerase chain reaction fragment was used to screen a rat kidney cDNA library and to isolate a cDNA clone encoding KAT/AadAT. Analysis of the combined DNA sequences indicated the presence of a single 1275-base pair open reading frame coding for a soluble protein of 425 amino acid residues. KAT/AadAT appears to be structurally homologous to aspartate aminotransferase in the pyridoxal 5'-phosphate binding domain. RNA blot analysis of rat tissues, including brain, revealed a single species of KAT/AadAT mRNA of approximately 2.1 kilobases. HEK-293 cells transfected with the KAT/AadAT cDNA exhibited both KAT and AadAT activities with enzymatic properties similar to those reported for the rat native protein.  (+info)

Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).
hsa:51166 K00825 kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39] , (RefSeq) AADAT, KAT2, KATII, KYAT2; aminoadipate aminotransferase (A) MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKT IQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQG LCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKP EDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNK FRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQ LMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKV KGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQL IKESL ...
AADAT Antibody (Cat. No. 48-417) can be used to detect Gibbon, Gorilla, Human, Monkey AADAT Antibody in IHC and other applications.
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This review provides a description of the biochemistry and enzymology of the α-aminoadipate pathway for lysine biosynthesis in fungi. The α-aminoadipate pathway is unique to fungi and is thus a potential target for the rational design of antifungal drugs. The present state of knowledge of the mechanisms of the seven enzymes in the pathway is presented, as well as detailed information with respect to structures and mechanisms of homocitrate synthase, saccharopine reductase, and saccharopine dehydrogenase. ...
AADAT Fragment MS Protein Standard, is a protein fragment containing a 50-150 amino acid sequence identical to part of a human AADAT protein target. The fragment MS Protein Standard represents a new category of using heavy isotope labeled (15N, 13C) Lysine and Arginine residues resulting in more than 99% isotope incorporation, as internal MS standards offering distinct advantages to existing products for relative and absolute quantification.
Accepted name: lysine-8-amino-7-oxononanoate transaminase. Reaction: L-lysine + 8-amino-7-oxononanoate = (S)-2-amino-6-oxohexanoate + 7,8-diaminononanoate. Glossary: (S)-2-amino-6-oxohexanoate = L-2-aminoadipate 6-semialdehyde = L-allysine. Other name(s): DAPA aminotransferase (ambiguous); bioA (gene name) (ambiguous); bioK (gene name). Systematic name: L-lysine:8-amino-7-oxononanoate aminotransferase. Comments: A pyridoxal 5-phosphate enzyme [2]. Participates in the pathway for biotin biosynthesis. The enzyme from the bacterium Bacillus subtilis cannot use S-adenosyl-L-methionine as amino donor and catalyses an alternative reaction for the conversion of 8-amino-7-oxononanoate to 7,8-diaminononanoate (cf. EC 2.6.1.62, adenosylmethionine-8-amino-7-oxononanoate transaminase).. Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:. References:. 1. Van Arsdell, S.W., Perkins, J.B., Yocum, R.R., Luan, L., Howitt, C.L., Chatterjee, N.P. and Pero, J.G. Removing a bottleneck in ...
The Summary of Product Characteristics (SPC or SmPC) is a specific document, the wording of which has been agreed with the regulatory authority as part of the medicine approval process. It is required before any medicine is allowed on the market in Europe. It is designed to assist doctors and pharmacists in prescribing and supplying the product ...
The KOMP Repository is located at the University of California Davis and Childrens Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at [email protected], US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors [email protected] or +1-510-450-7917 ...
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Rabbit polyclonal antibody raised to a synthetic peptide corresponding to residues 1-22 of Kynurenine Aminotransferase II (KAT II); the epitope for the antibody was derived from human protein sequence that shows homology to mouse protein sequence. ...
Ab Aadat Hogayi Hai Lockdown Ki, says Mehran. Even if I wanted to, I couldnt relate to him. The lockdowns that Mehran and I are used to are quite different. I was forced to stay indoors, to keep myself safe from a deadly virus. I was privileged, safe, with my family. I worked from home using my laptop and high speed-WiFi. I used the same network to conduct virtual Netflix Parties with my friends and video call them for hours. We challenged each other to upload photographs on Instagram and whip the perfect Dalgona Coffee. People like me went on virtual dates and attended paid online events. Once in a while, we drove our cars an extra kilometre, when we stepped out to buy essentials.. Mehran couldnt relate to my version of a lockdown ...
Background/Purpose: The chance of upper gastrointestinal blood loss (UGIB) increases in patients with coronary artery disease (CAD) because of the frequent usage of antiplatelets. had been significantly old, and had more often utilized antiplatelets and warfarin than in non-CAD individuals. Weighed against non-CAD, the CAD individuals had considerably higher GlasgowCBlatchford rating, complete and pre-endoscopic Rockall rating and complete. Peptic ulcer in CAD individuals was identified more regularly than in non-CAD individuals. UGIB individuals with CAD and non-CAD got similar outcomes in regards to to mortality price, re-bleeding, medical procedures, embolization, and loaded erythrocyte transfusion. Nevertheless, CAD individuals had longer length of hospital remains than non-CAD individuals. Two CAD individuals passed away from cardiac arrest after endoscopy, whereas three non-CAD individuals passed away from pneumonia and severe renal failure throughout their hospitalization. Summary: In ...
Data Availability StatementThe data used to support the results of the research are included within this article. wound healing, and transwell assays, indicating that miR-486-5p is an HCC suppressor. We employed four miRNA databases to predict the target genes of miR-486-5p and verified retrieved genes using qPCR and western blotting. The E3 ubiquitin ligase CBL was significantly downregulated by miR-486-5p overexpression in HCC cell lines at both mRNA and protein level, and overexpression of CBL counteracted the inhibitory effects of miR-486-5p on HCC cell proliferation and migration. Moreover, CBL expression was negatively correlated with miR-486-5p expression in HCC tissues. Collectively, our results suggest that miR-486-5p may S/GSK1349572 cell signaling act as a tumor suppressor gene in HCC by downregulating CBL expression. 1. Introduction Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third leading cause of cancer-related mortality [1]. Although ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
TY - JOUR. T1 - Lysine metabolism in mammalian brain. T2 - An update on the importance of recent discoveries. AU - Hallen, André. AU - Jamie, Joanne F.. AU - Cooper, Arthur J L. PY - 2013/12. Y1 - 2013/12. N2 - The lysine catabolism pathway differs in adult mammalian brain from that in extracerebral tissues. The saccharopine pathway is the predominant lysine degradative pathway in extracerebral tissues, whereas the pipecolate pathway predominates in adult brain. The two pathways converge at the level of δ1-piperideine-6-carboxylate (P6C), which is in equilibrium with its open-chain aldehyde form, namely, α-aminoadipate δ-semialdehyde (AAS). A unique feature of the pipecolate pathway is the formation of the cyclic ketimine intermediate δ1-piperideine-2- carboxylate (P2C) and its reduced metabolite l-pipecolate. A cerebral ketimine reductase (KR) has recently been identified that catalyzes the reduction of P2C to l-pipecolate. The discovery that this KR, which is capable of reducing not only ...
0026]1. Okuno E, Nishikawa T, M Nakamura, (1996) Kynurenine aminotransferases in the rat. Localization and Characterization. Recent Advances in Tryptophan Research, edited by Graziella Allegri Filipini et al., Plenum Press, New Your, 1996.2. B. Kepplinger, H. Baran, A. Kainz, H. Ferraz-Leite, J. Newcombe and P. Kalina (2005) Age-related increase of kynurenic acid in human cerebrospinal fluid: Positive corratio with IgG and Sa-microglobulin changes. Neurosignals, 14(3), 126-135.3. Kepplinger B, Baran H, Kainz A, Zeiner D, Wallner J (2006) Cerebrospinal Fluid of Multiple Sclerosis patients exert significantly weaker inhibition of Kynurenine Aminotransferase I activity in rat liver homogenate. Multiple Sclerosis 2006; 12:S1-S228, P4964. H. Baran, B. Kepplinger, M. Draxler and H. Ferraz-Leite (2004) Kynurenic acid metabolism in rat, piglet and human tissues. In European Society for Clinical Neuropharmacology by ed L. Battistin, International Proceedings MEDIMOND S.r.1. E505R9004, 227-231.5. H. ...
TEXTBOOKS. Goodman SI, Frerman FE. Organic acidemias due to defects in lysine oxidation: 2-ketoadipic acidemia and glutaric acidemia. In: Scriver CR, Beaudet AL, Sly WS, et al. Eds. The Metabolic Molecular Basis of Inherited Disease. 7th ed. McGraw-Hill Companies. New York, NY; 1995:1451-60.. JOURNAL ARTICLES. Bahr O, Mader I, Zschocke J, et al. Adult onset glutaric aciduria type I presenting with leukoencephalopathy. Neurology. 2002;59:1802-04.. Kolker S, Ramaekers VT, Zschocke J, et al. Acute encephalopathy despite early therapy in a patient with homozygosity for E365K in the glutaryl-coenzyme A dehydrogenase gene. J Pediatr 2001;138:277-79.. Zafeiriou DI, Zschocke J, Augustidou-Savvopoulou P, et al. Atypical and variable clinical presentation of glutaric aciduria type I. Neuropediatrics. 2000;31:303-06.. Kafil-Hussain NA, Monavari A, Bowell R, et al. Ocular findings in glutaric aciduria type I. J Pediatr Ophthalmol Strabismus. 2000;37:289-93.. Busquets C, Coll MJ, Merinero B, et al. Prenatal ...
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OVERVIEW: What every practitioner needs to know Are you sure your patient has glutaric aciduria type I? What are the typical findings for this disease? Glutaric aciduria type I (GA-I) should be considered in any patient who has a history of dystonia/dyskinesia with macrocephaly. Prior to these overt chronic neurologic symptoms, there is usually a…. ...
Penicillins (Penams) and cephalosporins (cephems) are beta-lactam antibiotics containing 6-aminopenicillanate (6-APA) and 7-aminocephalosporanate (7-ACA) nuclei, respectively. 6-APA and 7-ACA are key intermediates for a variety of semisynthetic penicillin and cephalosporin derivatives. Penicillins are produced only by fungi, while cephalosporins (including cephamycins) are produced by fungi and bacteria. Both antibiotics are synthesized from L-2-aminoadipate, L-cysteine and L-valine through a common pathway. It starts with the condensation of these three amino acids by the non-ribosomal peptide synthetase to form the tripeptide delta-(L-2-aminoadipyl)-L-cysteinyl-D-valine (ACV). The linear ACV tripeptide is then converted to bicyclic isopenicillin N by isopenicillin N synthase, in which the beta-lactam ring is formed. Isopenicillin N is the branch point of penicillin [MD:M00672] and cephalosporin [MD:M00673] pathways ...
Aminoadipic acid (2-aminoadipate) is a metabolite in the principal biochemical pathway of lysine. It is an intermediate in the metabolism (i.e. breakdown or degradation) of lysine and saccharopine.(Wikipedia). It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-methyl-D-aspartate; (NMDA). Aminoadipic has also been shown to inhibit the production of kynurenic acid in brain tissue slices (PMID: 8566117 ). Kynurenic acid is a broad spectrum excitatory amino acid receptor antagonist. Recent studies have shown that aminoadipic acid is elevated in prostate biopsy tissues from prostate cancer patients (PMID: 23737455 ). Mutations in DHTKD1 (dehydrogenase E1 and transketolase domain-containing protein 1) have been shown to cause human 2-aminoadipic and 2-oxoadipic aciduria via impaired turnover of decarboxylation 2-oxoadipate to glutaryl-CoA, which is the last step in the lysine degradation pathway (PMID: 23141293 ). Aging, diabetes, sepsis and renal failure are known to ...
Genetic testing for the GCDH gene, which is associated with glutaric aciduria type I (GA1) and elevated C5-DC on newborn screening (NBS) or acylcarnitine analysis.
1E5Q: Crystal Structure of Saccharopine Reductase from Magnaporthe Grisea, an Enzyme of the Alpha-Aminoadipate Pathway of Lysine Biosynthesis
3-methylglutaconic aciduria type 1 (3MGA1) is a genetic disorder in which the body cannot get energy from a substance called leucine. Leucine is one of the amino acids, which are the building blocks of proteins in our bodies. Because people with 3MGA1 cant break down leucine for energy to support muscle function and growth, they have a variety of symptoms that are present at birth. These symptoms may include developmental delays, seizures, muscle twitches (dystonia), and muscle weakness.. 3MGA1 is caused by a mutation (change) to the AUH gene, which produces a protein to break down leucine. When there is a mutation to the AUH gene, this protein either isnt produced or isnt functional, so the body cant get energy from leucine. Under normal conditions, the protein is present in the part of the cell that produces energy (the mitochondria), so 3MGA1 is a type of mitochondrial disease. 3MGA1 is also an organic acid condition because it causes harmful 3-methylglutaconic acid build up in the ...
Looking for online definition of Glutaric aciduria type 1 in the Medical Dictionary? Glutaric aciduria type 1 explanation free. What is Glutaric aciduria type 1? Meaning of Glutaric aciduria type 1 medical term. What does Glutaric aciduria type 1 mean?
Free, official coding info for 2018 ICD-10-CM E71.313 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
... glycine transaminase MeSH D08.811.913.477.700.535 - leucine transaminase MeSH D08.811.913.477.700.550 - l-lysine 6-transaminase ... l-aminoadipate-semialdehyde dehydrogenase MeSH D08.811.682.657.163.812 - malonate-semialdehyde dehydrogenase (acetylating) MeSH ... beta-alanine-pyruvate transaminase MeSH D08.811.913.477.700.347 - d-alanine transaminase MeSH D08.811.913.477.700.470 - ... transaminases MeSH D08.811.913.477.700.100 - alanine transaminase MeSH D08.811.913.477.700.120 - 2-aminoadipate transaminase ...
... aspartate transaminase EC 2.6.1.2: alanine transaminase EC 2.6.1.3: cysteine transaminase EC 2.6.1.4: glycine transaminase EC ... D-amino-acid transaminase EC 2.6.1.11: acetylornithine transaminase EC 2.6.1.12: alanine-oxo-acid transaminase EC 2.6.1.13: ... UDP-N-acetylbacillosamine transaminase EC 2.6.1.35: glycine-oxaloacetate transaminase EC 2.6.1.36: L-lysine 6-transaminase EC ... glutamine-phenylpyruvate transaminase EC 2.6.1.65: N6-acetyl-β-lysine transaminase EC 2.6.1.66: valine-pyruvate transaminase EC ...
... glutamic-ketoadipic transaminase, and glutamate-alpha-ketoadipate transaminase. This enzyme participates in lysine biosynthesis ... Matsuda M, Ogur M (1969). "Separation and specificity of the yeast glutamate-alpha-ketoadipate transaminase". J. Biol. Chem. ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ... Other names in common use include alpha-aminoadipate aminotransferase, 2-aminoadipate aminotransferase, 2-aminoadipic ...
In enzymology, a lysine-pyruvate 6-transaminase (EC 2.6.1.71) is an enzyme that catalyzes the chemical reaction L-lysine + ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ... 49 (2): 203-206. doi:10.1111/j.1574-6968.1988.tb02716.x. Portal: Biology v t e (EC 2.6.1, Enzymes of unknown structure, All ... L-2-aminoadipate 6-semialdehyde + L-alanine Thus, the two substrates of this enzyme are L-lysine and pyruvate, whereas its two ...
... belongs to the aminotransferase class-III family. Crystal structures of L-lysine 6-transaminase reveal ... In enzymology, a L-lysine 6-transaminase (EC 2.6.1.36) is an enzyme that catalyzes the chemical reaction L-lysine + 2- ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. This ... Other names in common use include lysine 6-aminotransferase, lysine epsilon-aminotransferase, lysine epsilon-transaminase, ...
It converts alpha-aminoadipate to alpha-ketoadipate. It is also one of the Kynurenine-oxoglutarate transaminases. GRCh38: ... Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, also known as alpha-aminoadipate aminotransferase and kynurenine ... PDBe-KB provides an overview of all the structure information available in the PDB for Human Kynurenine/alpha-aminoadipate ... "Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT)". Molecular Genetics and Metabolism. 76 ...
Han Q, Cai T, Tagle DA, Robinson H, Li J (August 2008). "Substrate specificity and structure of human aminoadipate ... Han Q, Cai T, Tagle DA, Robinson H, Li J (August 2008). "Substrate specificity and structure of human aminoadipate ... In enzymology, a kynurenine-oxoglutarate transaminase (EC 2.6.1.7) is an enzyme that catalyzes the chemical reaction L- ... This enzyme belongs to the family of transferases, to be specific, the transaminases, that transfer nitrogenous groups. The ...
It is formed from L-kynurenine in a reaction catalyzed by the enzyme kynurenine-oxoglutarate transaminase. KYNA has been ... "Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II". Bioscience Reports ... 92 (1-2): 203-9. doi:10.1016/j.physbeh.2007.05.025. PMID 17573079. S2CID 46156877. Erhardt S, Schwieler L, Engberg G (2003). " ... 330 (2): 265-72. doi:10.1016/0006-8993(85)90685-7. PMID 2985194. S2CID 24345638. Hilmas C, Pereira EF, Alkondon M, Rassoulpour ...
There are two distinct lysine biosynthetic pathways: the diaminopimelic acid pathway and the α-aminoadipate pathway. The most ... "MetaCyc: L-lysine biosynthesis I". PETERKOFSKY, B; GILVARG, C (May 1961). "N-Succinyl-L-diaminopimelic-glutamic transaminase". ... This reaction that removes the 2'-OH of the ribose sugar to generate deoxyribose is not affected by the bases attached to the ... 10 (2): 113-127. doi:10.1038/nrm2838. PMC 4461372. PMID 20094052. Green, Rachel; Harry F. Noller; et al. (1997). "Ribosomes and ...
Curated proteins matching [LysW]-aminoadipate semialdehyde transaminase. *Curated proteins matching [LysW]-aminoadipate ... LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 35%. 81%. 150.6. glutamate-1-semialdehyde 2,1- ... Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 33%. 57%. 99. ... Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.-; EC 2.6.1.118 (characterized, see ...
EC 2.6.1.62, adenosylmethionine 8-amino-7-oxononanoate transaminase).. The second product of the reaction, (S)-2-amino-6- ... Lysine--8-amino-7-oxononanoate transaminase. Alternative names. DAPA aminotransferase (ambiguous);. bioA (gene name) (ambiguous ... L-lysine + 8-amino-7-oxononanoate = (S)-2-amino-6-oxohexanoate + 7,8-diaminononanoate.. ...
2-aminoadipate transaminase. 64. SEQF3145,RYFV01000011.1. SEQF3145_00065 jb [NA] [AA] 957/318. 77403-78359. D-alanine--D- ... Acyl-CoA thioesterase 2. 99. SEQF3145,RYFV01000012.1. SEQF3145_00100 jb [NA] [AA] 1698/565. 32130-30433. Phosphoenolpyruvate- ... 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase. 24. SEQF3145,RYFV01000011.1. SEQF3145_00024 jb [NA] [AA] 600/ ... tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase. 173. SEQF3145,RYFV01000013.1. SEQF3145_00181 jb [NA] [AA] 1077/358. ...
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (3) * V-type proton ATPase subunit D (3) ... Probable kynurenine--oxoglutarate transaminase BNA3 (3) * Cystathionine gamma-synthase (3) * Thioredoxin-3, mitochondrial (3) ... Dolichyl-phosphate-mannose--protein mannosyltransferase 2 (4) * 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate ... 1-phosphatidylinositol 3-phosphate 5-kinase FAB1 (2) * Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W (2 ...
Alanine transaminase. Alanine--glyoxylate transaminase. Alanine--oxo-acid transaminase. Alanine--oxomalonate transaminase. ... Aminoadipate-semialdehyde dehydrogenase. Aminobenzoate decarboxylase. Aminobutyraldehyde dehydrogenase. Aminocarboxymuconate- ... Asparagine--oxo-acid transaminase. Asparagine--tRNA ligase. Asparaginyl-tRNA synthase (glutamine-hydrolyzing). Asparagusate ... Aspartate transaminase. Aspartate--ammonia ligase. Aspartate--ammonia ligase (ADP-forming). Aspartate--phenylpyruvate ...
2.6.1.5 tyrosine transaminase 2.6.1.51 serine---pyruvate transaminase 2.6.1.58 phenylalanine(histidine) transaminase - - - - - ... 2.6.1.2 alanine transaminase 2.6.1.44 alanine---glyoxylate transaminase 2.6.1.7 kynurenine---oxoglutarate transaminase - - - - ... 2.6.1.18 beta-alanine---pyruvate transaminase 2.6.1.2 alanine transaminase 2.6.1.4 glycine transaminase 2.6.1.40 (R)-3-amino-2- ... 2.6.1.51 serine---pyruvate transaminase 2.6.1.84 arginine---pyruvate transaminase 2.6.1.9 histidinol-phosphate transaminase - - ...
Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.-; EC 2.6.1.118 (characterized, see ... Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.-; EC 2.6.1.118 (characterized, see ... Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; EC 2.6.1.-; EC 2.6.1.118 (characterized, see ... Succinylornithine transaminase; SOAT; Succinylornithine aminotransferase; EC 2.6.1.81. 49%. 341.7. L-proline biosynthesis. argD ...
1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase 1.2.1.48 long-chain-aldehyde dehydrogenase 1.2.1.5 aldehyde dehydrogenase [ ... 2.6.1.18 beta-alanine---pyruvate transaminase - BRENDA: BS422438 benzaldehyde + 2-oxoglutarate <=> (5R)-5-hydroxy-4-oxo-5- ... S)-2-nitro-1-phenylethanol <=> Nitromethane + benzaldehyde + (R)-2-nitro-1-phenylethanol 4.1.2.47 (S)-hydroxynitrile lyase - ... benzaldehyde + acetaldehyde <=> (R)-benzoin + (S)-2-Hydroxypropiophenone 4.1.1.7 benzoylformate decarboxylase - BRENDA: ...
... glutamate semialdehyde transaminase. SMc02138. SM_b21186. lysK. [LysW]-lysine hydrolase / [LysW]-ornithine hydrolase. ... LysW]-2-aminoadipate 6-phosphate reductase / [LysW]-glutamylphosphate reductase. lysZ. [LysW]-2-aminoadipate 6-kinase / [LysW]- ... there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, ...
transaminase activity. 4. GO:0047536. 2-aminoadipate transaminase activity. 1. GO:0003700. transcription factor activity, ...
LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 31%. 94%. 193.7. beta-alanine-pyruvate transaminase ... LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 31%. 94%. 193.7. beta-alanine-pyruvate transaminase ... LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.- (uncharacterized). 31%. 94%. 193.7. beta-alanine-pyruvate transaminase ... beta-alanine-pyruvate transaminase (EC 2.6.1.18). 65%. 568.5. L-proline biosynthesis. argD. lo. Acetylornithine ...
... "aminoadipate-semialdehyde dehydrogenase small subunit (alpha-aminoadipate reductase), amino acid biosynthesis, aminoadipate- ... "phosphoserine transaminase,phosphoserine aminotransferase," YHR025W 143.39381 INESSENTIAL THR1 "homoserine kinase,homoserine ... transaminase (4-aminobutyrate aminotransferase),4-aminobutyrate aminotransferase, " YGR072W 8.896687 INESSENTIAL UPF3 "involved ... "Branched-Chain Amino Acid Transaminase,branched-chain amino acid aminotransferase," YEL065W -0.945446 INESSENTIAL SIT1 " ...
Transaminase, Glutamic-Oxaloacetic. *L-Aspartate-2-Oxoglutarate Aminotransferase. *Aminotransferase, L-Aspartate-2-Oxoglutarate ... Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L- ... Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation decreases ... attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2- ...
"Tryptophan Transaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Tryptophan Transaminase" by people in this website by year, ... Below are the most recent publications written about "Tryptophan Transaminase" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Tryptophan Transaminase". ...
aminoadipate aminotransferase. chr3_+_108541545. 0.13. ENST00000295756.6. TRAT1. T cell receptor associated transmembrane ... LIM domain only 2 (rhombotin-like 1). chr11_+_67798090. 0.13. ENST00000313468.5. NDUFS8. NADH dehydrogenase (ubiquinone) Fe-S ... thymidine kinase 2, mitochondrial. chr14_+_104182105. 0.07. ENST00000311141.2. ZFYVE21. zinc finger, FYVE domain containing 21 ... NudC domain containing 2. chr12_+_95611569. 0.08. ENST00000261219.6. ENST00000551472.1. ENST00000552821.1. VEZT. vezatin, ...
Dsui_2708: succinyldiaminopimelate transaminase. is similar to:. PaperBLAST. ArAT1 / D7F4K3: aromatic amino acid transaminase ( ... ARO8_YEAST / P53090: Aromatic/aminoadipate aminotransferase 1; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; ... tyrB / GB,AAC77024.1: aromatic-amino-acid transaminase TyrB; EC 2.6.1.57 from Escherichia coli. tyrB / P04693: tyrosine ... tyrB / GB,AAC77024.1: aromatic-amino-acid transaminase TyrB; EC 2.6.1.57 from Escherichia coli. tyrB / P04693: tyrosine ...
2.6.1 Transaminases. 2.6.1.118 [amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase. K05830 lysJ, argD; [ ... and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through alpha-aminoadipate. ... Aminotransferase (transaminase). Class III. K05830 lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L- ... Ontology (5) KEGG BRITE (3) COG (2) Pathway (14) KEGG PATHWAY (12) KEGG MODULE (2) Chemical reaction (6) KEGG ENZYME (2) KEGG ...
Transaminase A; EC 2.6.1.1; EC 2.6.1.39 (characterized) to candidate Pf1N1B4_4425 Aspartate aminotransferase (EC 2.6.1.1) ... Align Aspartate aminotransferase; AAT; AspAT; Putative 2-aminoadipate transaminase; ... 2 Number of sequences better than 1.0e-02: 1 Number of HSP's gapped: 1 Number of HSP's successfully gapped: 1 Length of query: ... there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, ...
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (3) * V-type proton ATPase subunit D (3) ... Probable kynurenine--oxoglutarate transaminase BNA3 (3) * Cystathionine gamma-synthase (3) * Thioredoxin-3, mitochondrial (3) ... Dolichyl-phosphate-mannose--protein mannosyltransferase 2 (4) * 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate ... 1-phosphatidylinositol 3-phosphate 5-kinase FAB1 (2) * Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W (2 ...
... glutamate semialdehyde transaminase. SMc02138. SM_b21186. lysK. [LysW]-lysine hydrolase / [LysW]-ornithine hydrolase. ... LysW]-2-aminoadipate 6-kinase / [LysW]-glutamate kinase. SMc01726. Confidence: high confidence medium confidence low confidence ... 2-aminoadipate/glutamate carrier protein. lysY. [LysW]-2-aminoadipate 6-phosphate reductase / [LysW]-glutamylphosphate ... there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, ...
... lysZYJ convert LysW-aminoadipate to LysW-lysine, and lysK releases lysine. ... glutamate semialdehyde transaminase. PGA1_c24230. PGA1_c28750. ... Comment: 2-oxoglutarate and acetyl-CoA are converted to ... 2-aminoadipate-LysW ligase. lysY. [LysW]-2-aminoadipate 6-phosphate reductase / [LysW]-glutamylphosphate reductase. PGA1_c17050 ... LysW]-2-aminoadipate 6-kinase / [LysW]-glutamate kinase. PGA1_c02050. Confidence: high confidence medium confidence low ...
Glutamine fructose 6-phosphate transaminase (isomerizing) [D08.811.913.477.700.500] Glutamine fructose 6-phosphate transaminase ... aminoadipate aminotransférase 2-aminoadipate: 2-oxoglutarate aminotransférase AadAT alpha-Aminoadipate aminotransférase ... aminoadipate aminotransférase. 2-aminoadipate: 2-oxoglutarate aminotransférase. AadAT. alpha-Aminoadipate aminotransférase. ... 2-aminoadipato transaminasa. Note dapplication:. Enzima que contiene PIRIDOXAL FOSFATO que cataliza la transferencia del grupo ...
transaminase activity. 4. GO:0047536. 2-aminoadipate transaminase activity. 1. GO:0003700. transcription factor activity, ...
Transaminase A; EC 2.6.1.1; EC 2.6.1.39 (characterized) to candidate Pf1N1B4_4425 Aspartate aminotransferase (EC 2.6.1.1) ... Align Aspartate aminotransferase; AAT; AspAT; Putative 2-aminoadipate transaminase; ... 2 Number of sequences better than 1.0e-02: 1 Number of HSPs gapped: 1 Number of HSPs successfully gapped: 1 Length of query: ... there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, ...
aminoadipate aminotransferase. chr3_+_108541545. 0.13. ENST00000295756.6. TRAT1. T cell receptor associated transmembrane ... LIM domain only 2 (rhombotin-like 1). chr11_+_67798090. 0.13. ENST00000313468.5. NDUFS8. NADH dehydrogenase (ubiquinone) Fe-S ... thymidine kinase 2, mitochondrial. chr14_+_104182105. 0.07. ENST00000311141.2. ZFYVE21. zinc finger, FYVE domain containing 21 ... NudC domain containing 2. chr12_+_95611569. 0.08. ENST00000261219.6. ENST00000551472.1. ENST00000552821.1. VEZT. vezatin, ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Fluoro-2-deoxyglucose use Fluorodeoxyglucose F18 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10- ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Oxoisovalerate Dehydrogenase (Lipoamide) use 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) 2-PAM Compounds use ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-Glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Fluoro-2-deoxyglucose use Fluorodeoxyglucose F18 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10- ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Oxoisovalerate Dehydrogenase (Lipoamide) use 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) 2-PAM Compounds use ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
4-Aminobutyrate Transaminase 4-Aminobutyric Acid use gamma-Aminobutyric Acid 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ... 2,6-Dichlorophenolindophenol use 2,6-Dichloroindophenol 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase use Progesterone Reductase ...
2.6.1.74 cephalosporin-C transaminase - BRENDA: BS356888 D-Aspartate + 2-oxoadipate <=> oxaloacetate + 2-Aminoadipate 2.6.1.74 ... 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase - - BRENDA: BS396383 D-serine + 2-oxoadipate <=> Hydroxypyruvate + 2- ... ATP + 2-Aminoadipate + L-cysteine <=> ADP + phosphate + DL-aminoadipyl-L-cysteine 6.3.2.2 glutamate---cysteine ligase - ... 2-piperidone-6-carboxylate + ATP + H2O <=> 2-Aminoadipate + phosphate + ADP 3.5.2.9 5-oxoprolinase (ATP-hydrolysing) - ...
2.6.1.5 tyrosine transaminase 2.6.1.51 serine---pyruvate transaminase 2.6.1.58 phenylalanine(histidine) transaminase - - - - - ... 2.6.1.2 alanine transaminase 2.6.1.44 alanine---glyoxylate transaminase 2.6.1.7 kynurenine---oxoglutarate transaminase - - - - ... 2.6.1.18 beta-alanine---pyruvate transaminase 2.6.1.2 alanine transaminase 2.6.1.4 glycine transaminase 2.6.1.40 (R)-3-amino-2- ... 2.6.1.51 serine---pyruvate transaminase 2.6.1.84 arginine---pyruvate transaminase 2.6.1.9 histidinol-phosphate transaminase - - ...
"Tryptophan Transaminase" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Tryptophan Transaminase" by people in this website by year, ... Below are the most recent publications written about "Tryptophan Transaminase" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Tryptophan Transaminase". ...
Kynurenine--oxoglutarate transaminase 1. Q16773 CCBL1. 9q34.11. Enzyme. Not Available. HMDBP03053. Aminoadipate ... Kynurenine--oxoglutarate transaminase 3. Q6YP21 CCBL2. 1p22.2. Enzyme. Not Available. Displaying all 5 metabolite protein links ... Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial. Q8N5Z0 AADAT. 4q33. Enzyme. Not Available. HMDBP00464. ...
"Tryptophan Transaminase" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Tryptophan Transaminase" by people in this website by year, ... Below are the most recent publications written about "Tryptophan Transaminase" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Tryptophan Transaminase". ...
EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of ... alanine transaminase. *: cysteine transaminase. *: glycine transaminase. *: tyrosine transaminase. *: leucine transaminase. *: ... thyroid-hormone transaminase. *: tryptophan transaminase. *: tryptophan-phenylpyruvate transaminase. *: diamine transaminase. ... b-alanine-pyruvate transaminase. *: 4-aminobutyrate transaminase. *: deleted. *: D-amino acid transaminase. *: (S)-3-amino-2- ...
2.6.1 Transaminases. 2.6.1.118 [amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase. K05830 lysJ, argD; [ ... and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through alpha-aminoadipate. ... Aminotransferase (transaminase). Class III. K05830 lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L- ... Ontology (5) KEGG BRITE (3) COG (2) Pathway (14) KEGG PATHWAY (12) KEGG MODULE (2) Chemical reaction (6) KEGG ENZYME (2) KEGG ...
4-Aminobutyrate Transaminase. 4-Aminobutyric Acid use gamma-Aminobutyric Acid. 4-Aminohippuric Acid use p-Aminohippuric Acid ... 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- ... 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester ... 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
The levels of glutamate-alpha-ketoadipate transaminase, an enzyme responsible for the conversion of alpha- aminoadipate to ... Use of alpha-aminoadipate and lysine as sole nitrogen source by Schizosaccharomyces pombe and selected pathogenic fungi. ... ketoadipate and alpha-aminoadipate-delta-semialdehyde when grown in medium containing alpha-aminoadipate and lysine, ... Also, 14C-alpha-aminoadipate was converted to 14C-alpha-ketoadipate in vivo. In the ammonium sulfate medium, S. pombe cells ...
... alpha-aminoadipate reductase), amino acid biosynthesis, aminoadipate-semialdehyde dehydrogenase, cytoplasm YOR303W 1230.967166 ... YOR184W 2167.216480 INESSENTIAL SER1 phosphoserine transaminase,phosphoserine aminotransferase, YJR109C 1533.292175 INESSENTIAL ... transaminase (4-aminobutyrate aminotransferase),4-aminobutyrate aminotransferase, YBR094W -0.939813 INESSENTIAL biological_ ... 2.258234 INESSENTIAL BAT2 Branched-Chain Amino Acid Transaminase,branched-chain amino acid aminotransferase, YDR109C -2.259435 ...
Transaminase, Glutamic-Oxaloacetic. *L-Aspartate-2-Oxoglutarate Aminotransferase. *Aminotransferase, L-Aspartate-2-Oxoglutarate ... Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L- ... Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation decreases ... attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2- ...
  • The fission yeast Schizosaccharomyces pombe and pathogenic fungi Candida albicans, Filobasidiella neoformans and Aspergillus fumigatus grew in the medium containing alpha-aminoadipate as the sole nitrogen source. (unipr.it)
  • When grown in the alpha-aminoadipate medium, only S. pombe accumulated a significant amount of alpha-ketoadipate in the culture supernatant. (unipr.it)
  • Also, 14C-alpha-aminoadipate was converted to 14C-alpha-ketoadipate in vivo. (unipr.it)
  • In the ammonium sulfate medium, S. pombe cells converted 14C- alpha-aminoadipate to lysine. (unipr.it)
  • The levels of glutamate-alpha-ketoadipate transaminase, an enzyme responsible for the conversion of alpha- aminoadipate to alpha-ketoadipate, and alpha-aminoadipate reductase, an enzyme required for the conversion of alpha-aminoadipate to lysine, were similar in S. pombe cells grown in the alpha-aminoadipate or ammonium sulfate medium. (unipr.it)
  • However, the level of homoisocitrate dehydrogenase, an enzyme before the alpha-ketoadipate step, was twelvefold lower in S. pombe cells grown in the alpha-aminoadipate medium compared to the level in cells grown in the ammonium sulfate medium. (unipr.it)
  • Pathogenic fungi used in this study did not accumulate alpha- ketoadipate and alpha-aminoadipate-delta-semialdehyde when grown in medium containing alpha-aminoadipate and lysine, respectively, as sole nitrogen source. (unipr.it)
  • However, only pathogenic fungi used both lysine and alpha-aminoadipate as sole nitrogen source. (unipr.it)
  • Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization. (musc.edu)
  • A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of amino group of L-2-aminoadipate onto 2-oxoglutarate to generate 2-oxoadipate and L-GLUTAMATE. (bvsalud.org)
  • This list contains a list of EC numbers for the second group, EC 2 , transferases , placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology . (en-academic.com)
  • For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. (lbl.gov)
  • This graph shows the total number of publications written about "Tryptophan Transaminase" by people in this website by year, and whether "Tryptophan Transaminase" was a major or minor topic of these publications. (ucdenver.edu)
  • Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. (musc.edu)
  • Below are the most recent publications written about "Tryptophan Transaminase" by people in Profiles. (ucdenver.edu)